RH50
label: RHAG
label: UniProt:Q02094 RHAG

Carbonic Anhydrase IV Hydrates Carbon Dioxide to Form a Proton and Bicarbonate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004089
BFO_0000050: Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
directly activates: Carbonic Anhydrase IV Dehydrates Bicarbonate to Yield Water and Carbon Dioxide
directly activates: Catalysis3083
label: H2O + CO2 -> H+ + HCO3-

Passive Transport of Carbon Dioxide into the Cell by AQP1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0035379
BFO_0000050: Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
directly activates: Carbonic Anhydrase I/II Hydrates Carbon Dioxide
directly activates: Bohr Effect
directly activates: Catalysis3077

Passive Transport of Carbon Dioxide into the Cell by RhAG
type: Restriction
  on property: enabled by
  some values from: RH50
type: Restriction
  on property: enabled by
  some values from: RH50
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0035379
BFO_0000050: Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
directly activates: Carbonic Anhydrase I/II Hydrates Carbon Dioxide
directly activates: Bohr Effect
directly activates: Catalysis3077

Carbonic Anhydrase I/II Hydrates Carbon Dioxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004089
BFO_0000050: Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
directly activates: Exchange of Cytosolic Bicarbonate for Extracellular Chloride by Band 3 Anion Exchanger (AE1, SLC4A1)
directly activates: Catalysis3078

Exchange of Cytosolic Bicarbonate for Extracellular Chloride by Band 3 Anion Exchanger (AE1, SLC4A1)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005452
BFO_0000050: Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
directly activates: Carbonic Anhydrase IV Dehydrates Bicarbonate to Yield Water and Carbon Dioxide
directly activates: Catalysis3083

Bohr Effect
type: GO_0003674
BFO_0000050: Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
label: Protonation and Carbamation of Hemoglobin A Causes Release of Oxygen

Haldane Effect
type: GO_0003674
BFO_0000050: Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
directly activates: Carbonic Anhydrase I/II Dehydrates Bicarbonate
directly activates: Passive Transport of Carbon Dioxide out of the Cell by AQP1
directly activates: Passive Transport of Carbon Dioxide out of the Cell by RhAG
directly activates: Catalysis3080
directly activates: Catalysis3081
directly activates: Catalysis3082
label: Hemoglobin A Binds Oxygen and Releases Protons and Carbon Dioxide

Exchange of Cytosolic Chloride for Extracellular Bicarbonate by Band 3 Anion Exchanger (AE1, SLC4A1)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005452
BFO_0000050: Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
directly activates: Carbonic Anhydrase I/II Dehydrates Bicarbonate
directly activates: Catalysis3080

Carbonic Anhydrase I/II Dehydrates Bicarbonate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004089
BFO_0000050: Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
directly activates: Passive Transport of Carbon Dioxide out of the Cell by AQP1
directly activates: Passive Transport of Carbon Dioxide out of the Cell by RhAG
directly activates: Catalysis3081
directly activates: Catalysis3082

Passive Transport of Carbon Dioxide out of the Cell by AQP1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0035379
BFO_0000050: Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes

Passive Transport of Carbon Dioxide out of the Cell by RhAG
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: RH50
type: Restriction
  on property: enabled by
  some values from: RH50
type: GO_0035379
BFO_0000050: Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes

Carbonic Anhydrase IV Dehydrates Bicarbonate to Yield Water and Carbon Dioxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004089
BFO_0000050: Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
label: H+ + HCO3- -> H2O + CO2

O2/CO2 exchange in erythrocytes
type: GO_0008150

Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
type: GO_0008150
BFO_0000050: O2/CO2 exchange in erythrocytes

Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
type: GO_0008150
BFO_0000050: O2/CO2 exchange in erythrocytes