PLK
PLK1
UniProt:P53350 PLK1
GWL
MASTL
THC2
UniProt:Q96GX5 MASTL
Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB
GOLGA2 phosphorylated by CDK1 is unable to promote fusion of ER to Golgi transport vesicles with cis-Golgi
Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65)
Activation of the Anaphase Promoting Complex (APC) by PLK1
PLK1 phosphorylates GORASP1
MAPK3-3 or MAPK1 phosphorylate GORASP2
GORASP1 phosphorylated by PLK1 and GORASP2 phosphorylated by MAPK3-3/MAPK1 are unable to promote Golgi cisternae stacking
CDK1 phosphorylates MASTL
MASTL (GWL) phosphorylates ARPP19
MASTL phosphorylates ENSA
p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D
CDK1:CCNB phosphorylates NEK9
PLK1 phosphorylates NEK9
NEK9 binds NEK6/NEK7 in the cytosol
NEK9 phosphorylates NEK6/NEK7
CDK1 phosphorylates NUP98
NEK6/NEK7 phosphorylates NUP98
VRK1/VRK2 phosphorylate BANF1
Mitotic Prophase
Golgi Cisternae Pericentriolar Stack Reorganization
MASTL Facilitates Mitotic Progression
Nuclear Envelope Breakdown
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly
Clearance of Nuclear Envelope Membranes from Chromatin