MAP2K6
label: MEK6
label: MKK6
label: PRKMK6
label: SKK3
label: UniProt:P52564 MAP2K6

CDO binds BOC
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: CDO binds promyogenic cadherins
directly activates: Neogenin:Netrin-3 binds CDO complex

CDO binds promyogenic cadherins
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Bnip2 interacts with CDO complex
directly activates: JLP interacts with CDO complex

Bnip2 interacts with CDO complex
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Interaction of Bnip-2 with Cdc42

Interaction of Bnip-2 with Cdc42
type: GO_0003674
BFO_0000050: CDO in myogenesis

JLP interacts with CDO complex
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Interaction of ABL1 with CDO complex

Interaction of ABL1 with CDO complex
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Interaction of p38 MAPK with JLP

Interaction of p38 MAPK with JLP
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Activation of p38 alpha/beta MAPK
directly activates: Catalysis3211

Activation of p38 alpha/beta MAPK
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: MAP2K6
type: GO_0004708
BFO_0000050: CDO in myogenesis
directly activates: Nuclear translocation of p38 MAPK

Nuclear translocation of p38 MAPK
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Phosphorylation of E proteins by p38 MAPK
directly activates: Phosphorylation of MEF2 proteins by p38
directly activates: Catalysis3212
directly activates: Catalysis3213

Phosphorylation of E proteins by p38 MAPK
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0004674
BFO_0000050: CDO in myogenesis
directly activates: Heterodimerization of E proteins with Myod

Heterodimerization of E proteins with Myod
type: GO_0003674
BFO_0000050: CDO in myogenesis
directly activates: Interaction of MyoD:E protein with MEF2

Phosphorylation of MEF2 proteins by p38
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0004674
BFO_0000050: CDO in myogenesis
directly activates: Interaction of MyoD:E protein with MEF2

Interaction of MyoD:E protein with MEF2
type: GO_0003674
BFO_0000050: CDO in myogenesis

Neogenin:Netrin-3 binds CDO complex
type: GO_0003674
BFO_0000050: CDO in myogenesis

CDO in myogenesis
type: GO_0008150