Gene Ontology Definition Changes
Files used:
- file 1 (old): 23:09:2011 13:54, cvs revision 1.2279
- file 2 (new): 30:09:2011 14:21, cvs revision 1.2291
- Database: unknown DB type, unknown DB release name
Terms with changed definitions
GO:0045039 : protein import into mitochondrial inner membrane
OLD: The import of proteins into the mitochondria inner membrane. Inner membrane proteins are first imported into the matrix space where the matrix-targeting sequence is removed; how these proteins then are incorporated into the inner membrane is not known.
NEW: The process comprising the import of proteins into the mitochondrion from outside the organelle and their insertion into the mitochondrial inner membrane. The translocase of the outer membrane complex mediates the passage of these proteins across the outer membrane, after which they are guided by either of two inner membrane translocase complexes into their final destination in the inner membrane.
GO:0045040 : protein import into mitochondrial outer membrane
OLD: The import of proteins into the outer membrane of the mitochondrion. Outer membrane proteins have a short matrix-targeting sequence followed by a long stretch of hydrophobic amino acids at the N-terminus. The hydrophobic sequence functions as a stop-transfer sequence that both prevents transfer of the protein into the matrix and anchors it as an integral protein in the outer membrane.
NEW: The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.