LIG1
UniProt:P18858 LIG1
FEN1
RAD2
UniProt:P39748 FEN1
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere
RFC binding displaces Pol Alpha on the C-strand of the telomere
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere
RFC dissociates after sliding clamp formation on the C-strand of the telomere
Formation of Processive Complex on the C-strand of the telomere
Formation of C-strand Okazaki fragments
Formation of the Flap Intermediate on the C-strand
RPA binds to the Flap on the C-strand
Recruitment of Dna2 endonuclease to the C strand
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand
Removal of remaining Flap from the C-strand
Joining of adjacent Okazaki fragments of the C-strand
Disassociation of Processive Complex and Completed Telomere End
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Removal of the Flap Intermediate from the C-strand