Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4
type: GO_0003674
BFO_0000050: Signaling by Activin
directly activates: The SMAD2/3:SMAD4 complex transfers to the nucleus
directly activates: BiochemicalReaction325

The SMAD2/3:SMAD4 complex transfers to the nucleus
type: GO_0003674
BFO_0000050: Signaling by Activin
directly activates: BiochemicalReaction324
directly activates: BiochemicalReaction331
directly activates: BiochemicalReaction333
directly activates: BiochemicalReaction335
directly activates: BiochemicalReaction336
directly activates: BiochemicalReaction337
directly activates: BiochemicalReaction340
directly activates: BiochemicalReaction349
directly activates: BiochemicalReaction350
directly activates: BiochemicalReaction352
directly activates: Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXH1 Binds Activin Response Element
directly activates: BiochemicalReaction6282
directly activates: Catalysis115
directly activates: Catalysis123
directly activates: Control22
directly activates: Control356
directly activates: Degradation4

Activin A/AB/B Binds Activin Receptor ACVR2A/B:ACVR1B
type: GO_0003674
BFO_0000050: Signaling by Activin
directly activates: ACVR2A/B (ActRIIA/B) Phosphorylates ACVR1B (ActRIB, ALK4) in Response to Activin
directly activates: Catalysis1941

Activin AB/B Binds Activin Receptor ACVR2A/B:ACVR1C
type: GO_0003674
BFO_0000050: Signaling by Activin
directly activates: ACVR2A/B (ActRIIA/B) Phosphorylates ACVR1C (ActRIC, ALK7) in Response to Activin
directly activates: Catalysis1942

ACVR2A/B (ActRIIA/B) Phosphorylates ACVR1B (ActRIB, ALK4) in Response to Activin
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004674
BFO_0000050: Signaling by Activin
directly activates: Phosphorylation of SMAD2/3 by Activin:Activin Receptor
directly activates: Catalysis1943

ACVR2A/B (ActRIIA/B) Phosphorylates ACVR1C (ActRIC, ALK7) in Response to Activin
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004674
BFO_0000050: Signaling by Activin
directly activates: Phosphorylation of SMAD2/3 by Activin:Activin Receptor
directly activates: Catalysis1943

Phosphorylation of SMAD2/3 by Activin:Activin Receptor
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004674
BFO_0000050: Signaling by Activin
directly activates: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4

Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXH1 Binds Activin Response Element
type: GO_0003674
BFO_0000050: Signaling by Activin

FSTL3 binds Activin
type: GO_0003674
BFO_0000050: Antagonism of Activin by Follistatin

Follistatin (FST) binds Activin
type: GO_0003674
BFO_0000050: Antagonism of Activin by Follistatin

Signaling by Activin
type: GO_0008150

Antagonism of Activin by Follistatin
type: GO_0008150
BFO_0000050: Signaling by Activin