MBTPS2
label: S2P
label: UniProt:O43462 MBTPS2

KIAA0091
label: MBTPS1
label: S1P
label: SKI1
label: UniProt:Q14703 MBTPS1

Dissociation of ATF6-alpha:BiP Complex
type: GO_0003674
BFO_0000050: Activation of Chaperones by ATF6-alpha
directly activates: Translocation of ATF6-alpha to the Golgi

Translocation of ATF6-alpha to the Golgi
type: GO_0003674
BFO_0000050: Activation of Chaperones by ATF6-alpha
directly activates: Cleavage of ATF6-alpha by S1P
directly activates: Catalysis1626

Cleavage of ATF6-alpha by S1P
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: KIAA0091
type: GO_0004252
BFO_0000050: Activation of Chaperones by ATF6-alpha
directly activates: Cleavage of ATF6-alpha by S2P
directly activates: Catalysis1627

Cleavage of ATF6-alpha by S2P
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: MBTPS2
type: GO_0008237
BFO_0000050: Activation of Chaperones by ATF6-alpha
directly activates: Translocation of ATF6-alpha to the Nucleus

Translocation of ATF6-alpha to the Nucleus
type: GO_0003674
BFO_0000050: Activation of Chaperones by ATF6-alpha
directly activates: Expression of BIP (78 kDa Glucose-regulated protein, GRP78, HSPA5)
directly activates: Expression of CHOP (DDIT3, GADD153)
directly activates: Expression of Calreticulin
directly activates: Expression of HSP90B1 (Endoplasmin)
directly activates: Expression of Xbp1(S)
directly activates: TemplateReactionRegulation66
directly activates: TemplateReactionRegulation67
directly activates: TemplateReactionRegulation68
directly activates: TemplateReactionRegulation69
directly activates: TemplateReactionRegulation70
directly activates: TemplateReactionRegulation71
directly activates: TemplateReactionRegulation72
directly activates: TemplateReactionRegulation73
directly activates: TemplateReactionRegulation74
directly activates: TemplateReactionRegulation75

Activation of Chaperones by ATF6-alpha
type: GO_0008150

Activation of Chaperone Genes by ATF6-alpha
type: GO_0008150
BFO_0000050: Activation of Chaperones by ATF6-alpha

Expression of BIP (78 kDa Glucose-regulated protein, GRP78, HSPA5)
type: GO_0003674
BFO_0000050: Activation of Chaperone Genes by ATF6-alpha

Expression of CHOP (DDIT3, GADD153)
type: GO_0003674
BFO_0000050: Activation of Chaperone Genes by ATF6-alpha

Expression of Calreticulin
type: GO_0003674
BFO_0000050: Activation of Chaperone Genes by ATF6-alpha

Expression of HSP90B1 (Endoplasmin)
type: GO_0003674
BFO_0000050: Activation of Chaperone Genes by ATF6-alpha

Expression of Xbp1(S)
type: GO_0003674
BFO_0000050: Activation of Chaperone Genes by ATF6-alpha