GO Monthly Release Notes for May 2005 ======================== Generated on Fri Jun 17 13:03:15 2005 Files used: gene_ontology.obo OLD: version 3.858, 29:04:2005 13:43 NEW: version 3.903, 27:05:2005 14:58 goslim_generic Key: |----1----||----2-----||-3--||4||----5----||-----------6-----------| GO:0009941 GO:0009536 TAIR D SF:575119 chloroplast envelope (obs) 1. GO ID number 2. GO-slim term(s) that new term was added under or "obs" if the term is obsolete. Terms with more than one GO-slim parent have further parents listed underneath the first parent. 3. Database that added term 4. indicates the existence of a definition for the term 5. the sourceforge request ID the term was added in response to 6. term name Columns are tab-delimited and can be imported into Excel for ease of reading. New terms in biological_process ontology (95 new terms) GO:0001952 GO:0007154 MGI D 1035336 regulation of cell-matrix adhesion GO:0001953 GO:0007154 MGI D 1035336 negative regulation of cell-matrix adhesion GO:0001954 GO:0007154 MGI D 1035336 positive regulation of cell-matrix adhesion GO:0031396 GO:0006464 MAH D 1191240 regulation of protein ubiquitination GO:0031397 GO:0006464 MAH D 1191240 negative regulation of protein ubiquitination GO:0031398 GO:0006464 MAH D 1191240 positive regulation of protein ubiquitination GO:0031399 GO:0006464 MAH D 1191240 regulation of protein modification GO:0031400 GO:0006464 MAH D 1191240 negative regulation of protein modification GO:0031401 GO:0006464 MAH D 1191240 positive regulation of protein modification GO:0031407 GO:0006629 MAH D 1198287 oxylipin metabolism GO:0031408 GO:0006629 MAH D 1198287 oxylipin biosynthesis GO:0009058 GO:0031412 GO:0006996 MAH D 1171962 gas vesicle organization and biogenesis GO:0031413 GO:0007582 MAH D 1171962 buoyancy regulation GO:0031424 GO:0009653 MAH D 1202738 keratinization GO:0030154 GO:0031425 GO:0006139 MAH D 1189818 chloroplast RNA processing GO:0031426 GO:0006139 MAH D 1189818 polycistronic mRNA processing GO:0031427 GO:0009628 MAH D 1035336 response to methotrexate GO:0043339 GO:0007010 JL D 1192419 establishment and/or maintenance of neuroblast polarity (sensu Nematoda and Protostomia) GO:0009653 GO:0043340 GO:0007010 JL D 1192419 establishment of neuroblast polarity (sensu Nematoda and Protostomia) GO:0009653 GO:0043341 GO:0007010 JL D 1192419 maintenance of neuroblast polarity (sensu Nematoda and Protostomia) GO:0009653 GO:0043342 GO:0007010 JL D 1192419 establishment and/or maintenance of neuroblast polarity (sensu Vertebrata) GO:0009653 GO:0043343 GO:0007010 JL D 1192419 establishment of neuroblast polarity (sensu Vertebrata) GO:0009653 GO:0043344 GO:0007010 JL D 1192419 maintenance of neuroblast polarity (sensu Vertebrata) GO:0009653 GO:0043345 GO:0007582 JL D 1192419 neuroblast division (sensu Vertebrata) GO:0009653 GO:0030154 GO:0043346 GO:0007582 JL D 1192419 neuroblast division (sensu Nematoda and Protostomia) GO:0009653 GO:0030154 GO:0043347 GO:0009653 JL D 1192419 neuroblast fate determination (sensu Nematoda and Protostomia) GO:0030154 GO:0043348 GO:0009653 JL D 1192419 neuroblast fate determination (sensu Vertebrata) GO:0030154 GO:0043349 GO:0008283 JL D 1192419 neuroblast proliferation (sensu Nematoda and Protostomia) GO:0009653 GO:0043350 GO:0008283 JL D 1192419 neuroblast proliferation (sensu Vertebrata) GO:0009653 GO:0043351 GO:0007582 JL D 1192419 neuroblast activation (sensu Nematoda and Protostomia) GO:0009653 GO:0043352 GO:0007582 JL D 1192419 neuroblast activation (sensu Vertebrata) GO:0009653 GO:0043353 GO:0030154 JL D 1192419 enucleate erythrocyte differentiation GO:0043354 GO:0009653 JL D 1192419 enucleate erythrocyte maturation GO:0016043 GO:0030154 GO:0043355 GO:0009653 JL D 1192419 epidermal cell differentiation (sensu Insecta) GO:0030154 GO:0043356 GO:0030154 JL D 1192419 epidermal cell fate specification (sensu Insecta) GO:0043357 GO:0030154 JL D 1192419 pigment cell differentiation (sensu Nematoda and Protostomia) GO:0043358 GO:0030154 JL D 1192419 pigment cell differentiation (sensu Vertebrata) GO:0043359 GO:0007582 JL D 1192419 glial cell migration (sensu Nematoda and Protostomia) GO:0007610 GO:0009653 GO:0043360 GO:0009653 JL D 1192419 glial cell differentiation (sensu Nematoda and Protostomia) GO:0030154 GO:0043361 GO:0009653 JL D 1192419 glial cell fate determination (sensu Nematoda and Protostomia) GO:0030154 GO:0043362 GO:0009653 JL D 1192419 nucleate erythrocyte maturation GO:0016043 GO:0030154 GO:0043363 GO:0030154 JL D 1192419 nucleate erythrocyte differentiation GO:0043366 GO:0009607 JL D 1156207 beta selection GO:0030154 GO:0043367 GO:0009607 JL D 1156207 CD4-positive T cell differentiation GO:0030154 GO:0043368 GO:0009607 JL D 1156207 positive T cell selection GO:0030154 GO:0043369 GO:0009607 JL D 1156207 CD4-positive or CD8-positive T cell lineage commitment GO:0030154 GO:0043370 GO:0009607 JL D 1156207 regulation of CD4-positive T cell differentiation GO:0030154 GO:0043371 GO:0009607 JL D 1156207 negative regulation of CD4-positive T cell differentiation GO:0030154 GO:0043372 GO:0009607 JL D 1156207 positive regulation of CD4-positive T cell differentiation GO:0030154 GO:0043373 GO:0009607 JL D 1156207 CD4-positive T cell lineage commitment GO:0030154 GO:0043374 GO:0009607 JL D 1156207 CD8-positive T cell differentiation GO:0030154 GO:0043375 GO:0009607 JL D 1156207 CD8-positive T cell lineage commitment GO:0030154 GO:0043376 GO:0009607 JL D 1156207 regulation of CD8-positive T cell differentiation GO:0030154 GO:0043377 GO:0009607 JL D 1156207 negative regulation of CD8-positive T cell differentiation GO:0030154 GO:0043378 GO:0009607 JL D 1156207 positive regulation of CD8-positive T cell differentiation GO:0030154 GO:0043379 GO:0009607 JL D 1156207 memory T cell differentiation GO:0030154 GO:0043380 GO:0009607 JL D 1156207 regulation of memory T cell differentiation GO:0030154 GO:0043381 GO:0009607 JL D 1156207 negative regulation of memory T cell differentiation GO:0030154 GO:0043382 GO:0009607 JL D 1156207 positive regulation of memory T cell differentiation GO:0030154 GO:0043383 GO:0009607 JL D 1156207 negative T cell selection GO:0030154 GO:0043385 GO:0009628 JL D 1035336 mycotoxin metabolism GO:0019748 GO:0043386 GO:0009058 JL D 1035336 mycotoxin biosynthesis GO:0009628 GO:0019748 GO:0043387 GO:0009056 JL D 1035336 mycotoxin catabolism GO:0009628 GO:0019748 GO:0043388 GO:0006259 JL D 1207105 positive regulation of DNA binding GO:0043389 GO:0009628 JL D 1035336 aflatoxin B metabolism GO:0019748 GO:0043390 GO:0009628 JL D 1035336 aflatoxin B1 metabolism GO:0019748 GO:0043391 GO:0009628 JL D 1035336 aflatoxin B2 metabolism GO:0019748 GO:0043392 GO:0006259 JL D 1207105 negative regulation of DNA binding GO:0043393 GO:0008150 JL D 1205888 regulation of protein binding GO:0048533 GO:0030154 JIC D 1186080 sporocyte differentiation GO:0048534 GO:0007275 JIC D 1185172 hemopoietic or lymphoid organ development GO:0048535 GO:0007275 JIC D 1185172 lymph node development GO:0048536 GO:0007275 JIC D 1185172 spleen development GO:0048537 GO:0007275 JIC D 1185172 mucosal-associated lymphoid tissue development GO:0048538 GO:0007275 JIC D 1185172 thymus development GO:0048539 GO:0007275 JIC D 1185172 bone marrow development GO:0048540 GO:0007275 JIC D 1185172 bursa development GO:0048541 GO:0007275 JIC D 1185172 Peyer's patch development GO:0048542 GO:0007275 JIC D 1185172 lymph gland development (sensu Arthropoda) GO:0048543 GO:0009058 JIC D 1207904 phytochrome chromophore biosynthesis GO:0019748 GO:0048544 GO:0007154 JIC D 1035336 recognition or rejection of self pollen GO:0007582 GO:0048545 GO:0009719 JIC D 1209738 response to steroid hormone stimulus GO:0048546 GO:0009653 JIC D 1209389 digestive tract morphogenesis GO:0048547 GO:0009653 JIC D 1209389 gut morphogenesis GO:0048548 GO:0006810 JIC D 1205241 regulation of pinocytosis GO:0048549 GO:0006810 JIC D 1205241 positive regulation of pinocytosis GO:0048550 GO:0006810 JIC D 1205241 negative regulation of pinocytosis GO:0048552 GO:0008150 JIC D 1205241 regulation of metalloenzyme activity GO:0048553 GO:0008150 JIC D 1205241 negative regulation of metalloenzyme activity GO:0048554 GO:0008150 JIC D 1205241 positive regulation of metalloenzyme activity GO:0051365 GO:0006950 AI D cellular response to potassium ion starvation GO:0007154 GO:0009605 GO:0051366 GO:0006464 AI D protein amino acid decanoylation GO:0051367 GO:0006464 AI D peptidyl-serine decanoylation GO:0051368 GO:0006464 AI D peptidyl-threonine octanoylation GO:0051369 GO:0006464 AI D peptidyl-threonine decanoylation New obsoletions in biological_process ontology GO:0006484, protein cysteine-thiol oxidation: represents a single activity. GO:0010156, sporocyte morphogenesis: was incorrectly defined. Term name changes in biological_process ontology GO:0000004: biological_process unknown --> biological process unknown GO:0001549: ovarian cumulus cell differentiation --> cumulus cell differentiation GO:0001710: mesoderm cell fate commitment --> mesodermal cell fate commitment GO:0001711: endoderm cell fate commitment --> endodermal cell fate commitment GO:0001714: endoderm cell fate specification --> endodermal cell fate specification GO:0001764: neuronal migration --> neuron migration GO:0001768: establishment of T-cell polarity --> establishment of T cell polarity GO:0001769: establishment of B-cell polarity --> establishment of B cell polarity GO:0001777: T-cell homeostatic proliferation --> T cell homeostatic proliferation GO:0001782: B-cell homeostasis --> B cell homeostasis GO:0001783: programmed cell death, B-cells --> programmed cell death, B cells GO:0001865: NK T-cell differentiation --> NK T cell differentiation GO:0001866: NK T-cell proliferation --> NK T cell proliferation GO:0001913: T-cell mediated cytotoxicity --> T cell mediated cytotoxicity GO:0001914: regulation of T-cell mediated cytotoxicity --> regulation of T cell mediated cytotoxicity GO:0001915: negative regulation of T-cell mediated cytotoxicity --> negative regulation of T cell mediated cytotoxicity GO:0001916: positive regulation of T-cell mediated cytotoxicity --> positive regulation of T cell mediated cytotoxicity GO:0001922: B-1 B-cell homeostasis --> B-1 B cell homeostasis GO:0001923: B-1 B-cell differentiation --> B-1 B cell differentiation GO:0001924: regulation of B-1 B-cell differentiation --> regulation of B-1 B cell differentiation GO:0001925: negative regulation of B-1 B-cell differentiation --> negative regulation of B-1 B cell differentiation GO:0001926: positive regulation of B-1 B-cell differentiation --> positive regulation of B-1 B cell differentiation GO:0006924: programmed cell death, activated T-cells --> programmed cell death, activated T cells GO:0007158: neuronal cell adhesion --> neuron adhesion GO:0007159: leukocyte cell adhesion --> leukocyte adhesion GO:0007282: cystoblast cell division --> cystoblast division GO:0007286: spermatid cell development --> spermatid development GO:0007294: oocyte cell fate determination (sensu Insecta) --> oocyte fate determination (sensu Insecta) GO:0007298: border cell migration (sensu Insecta) --> border follicle cell migration (sensu Insecta) GO:0007400: neuroblast cell fate determination --> neuroblast fate determination GO:0007425: tracheal cell fate determination (sensu Insecta) --> tracheal epithelial cell fate determination (sensu Insecta) GO:0007427: tracheal cell migration (sensu Insecta) --> tracheal epithelial cell migration (sensu Insecta) GO:0007493: endoderm cell fate determination --> endodermal cell fate determination GO:0007500: mesoderm cell fate determination --> mesodermal cell fate determination GO:0007501: mesoderm cell fate specification --> mesodermal cell fate specification GO:0008038: neuronal cell recognition --> neuron recognition GO:0008078: mesoderm cell migration --> mesodermal cell migration GO:0008101: dpp receptor signaling pathway --> decapentaplegic receptor signaling pathway GO:0008347: glia cell migration --> glial cell migration GO:0009563: synergid cell differentiation --> synergid differentiation GO:0009912: auditory hair cell fate commitment --> auditory receptor cell fate commitment GO:0009999: negative regulation of auditory hair cell fate specification --> negative regulation of auditory receptor cell fate specification GO:0010026: trichome cell differentiation (sensu Magnoliophyta) --> trichome differentiation (sensu Magnoliophyta) GO:0010198: synergid cell death --> synergid death GO:0016322: neuronal remodeling --> neuron remodeling GO:0019724: B-cell mediated immunity --> B cell mediated immunity GO:0030099: myeloid blood cell differentiation --> myeloid cell differentiation GO:0030183: B-cell differentiation --> B cell differentiation GO:0030217: T-cell differentiation --> T cell differentiation GO:0030221: basophil cell differentiation --> basophil differentiation GO:0030709: border cell delamination --> border follicle cell delamination GO:0030710: regulation of border cell delamination --> regulation of border follicle cell delamination GO:0030711: positive regulation of border cell delamination --> positive regulation of border follicle cell delamination GO:0030712: negative regulation of border cell delamination --> negative regulation of border follicle cell delamination GO:0030716: oocyte cell fate determination --> oocyte fate determination GO:0030846: transcription termination from Pol II promoter, RNA polyymerase(A) coupled --> transcription termination from Pol II promoter, RNA polymerase(A) coupled GO:0030847: transcription termination from Pol II promoter, RNA polyymerase(A)-independent --> transcription termination from Pol II promoter, RNA polymerase(A)-independent GO:0030888: regulation of B-cell proliferation --> regulation of B cell proliferation GO:0030889: negative regulation of B-cell proliferation --> negative regulation of B cell proliferation GO:0030890: positive regulation of B-cell proliferation --> positive regulation of B cell proliferation GO:0031295: T-cell costimulation --> T cell costimulation GO:0031296: B-cell costimulation --> B cell costimulation GO:0035099: hemocyte cell migration (sensu Arthropoda) --> hemocyte migration (sensu Arthropoda) GO:0035153: tracheal cell type specification --> tracheal epithelial cell type specification GO:0035167: lymph gland hemopoiesis --> lymph gland hemopoiesis (sensu Arthropoda) GO:0042055: neuronal lineage restriction --> neuron lineage restriction GO:0042098: T-cell proliferation --> T cell proliferation GO:0042100: B-cell proliferation --> B cell proliferation GO:0042102: positive regulation of T-cell proliferation --> positive regulation of T cell proliferation GO:0042103: positive regulation of T-cell homeostatic proliferation --> positive regulation of T cell homeostatic proliferation GO:0042104: positive regulation of activated T-cell proliferation --> positive regulation of activated T cell proliferation GO:0042110: T-cell activation --> T cell activation GO:0042113: B-cell activation --> B cell activation GO:0042129: regulation of T-cell proliferation --> regulation of T cell proliferation GO:0042130: negative regulation of T-cell proliferation --> negative regulation of T cell proliferation GO:0042491: auditory hair cell differentiation --> auditory receptor cell differentiation GO:0042492: gamma-delta T-cell differentiation --> gamma-delta T cell differentiation GO:0042661: regulation of mesoderm cell fate specification --> regulation of mesodermal cell fate specification GO:0042662: negative regulation of mesoderm cell fate specification --> negative regulation of mesodermal cell fate specification GO:0042663: regulation of endoderm cell fate specification --> regulation of endodermal cell fate specification GO:0042664: negative regulation of endoderm cell fate specification --> negative regulation of endodermal cell fate specification GO:0042667: auditory hair cell fate specification --> auditory receptor cell fate specification GO:0042668: auditory hair cell fate determination --> auditory receptor cell fate determination GO:0042669: regulation of auditory hair cell fate specification --> regulation of auditory receptor cell fate specification GO:0042722: alpha-beta T-cell activation by superantigen --> alpha-beta T cell activation by superantigen GO:0043029: T-cell homeostasis --> T cell homeostasis GO:0043158: heterocyst cell differentiation --> heterocyst differentiation GO:0043316: cytotoxic T-cell degranulation --> cytotoxic T cell degranulation GO:0043317: regulation of cytotoxic T-cell degranulation --> regulation of cytotoxic T cell degranulation GO:0043318: negative regulation of cytotoxic T-cell degranulation --> negative regulation of cytotoxic T cell degranulation GO:0043319: positive regulation of cytotoxic T-cell degranulation --> positive regulation of cytotoxic T cell degranulation GO:0045034: neuroblast cell division --> neuroblast division GO:0045058: T-cell selection --> T cell selection GO:0045059: positive thymic T-cell selection --> positive thymic T cell selection GO:0045060: negative thymic T-cell selection --> negative thymic T cell selection GO:0045061: thymic T-cell selection --> thymic T cell selection GO:0045062: extrathymic T-cell selection --> extrathymic T cell selection GO:0045065: cytotoxic T-cell differentiation --> cytotoxic T cell differentiation GO:0045066: regulatory T-cell differentiation --> regulatory T cell differentiation GO:0045067: positive extrathymic T-cell selection --> positive extrathymic T cell selection GO:0045068: negative extrathymic T-cell selection --> negative extrathymic T cell selection GO:0045196: establishment and/or maintenance of neuroblast cell polarity --> establishment and/or maintenance of neuroblast polarity GO:0045200: establishment of neuroblast cell polarity --> establishment of neuroblast polarity GO:0045201: maintenance of neuroblast cell polarity --> maintenance of neuroblast polarity GO:0045444: adipocyte differentiation --> fat cell differentiation GO:0045577: regulation of B-cell differentiation --> regulation of B cell differentiation GO:0045578: negative regulation of B-cell differentiation --> negative regulation of B cell differentiation GO:0045579: positive regulation of B-cell differentiation --> positive regulation of B cell differentiation GO:0045580: regulation of T-cell differentiation --> regulation of T cell differentiation GO:0045581: negative regulation of T-cell differentiation --> negative regulation of T cell differentiation GO:0045582: positive regulation of T-cell differentiation --> positive regulation of T cell differentiation GO:0045583: regulation of cytotoxic T-cell differentiation --> regulation of cytotoxic T cell differentiation GO:0045584: negative regulation of cytotoxic T-cell differentiation --> negative regulation of cytotoxic T cell differentiation GO:0045585: positive regulation of cytotoxic T-cell differentiation --> positive regulation of cytotoxic T cell differentiation GO:0045586: regulation of gamma-delta T-cell differentiation --> regulation of gamma-delta T cell differentiation GO:0045587: negative regulation of gamma-delta T-cell differentiation --> negative regulation of gamma-delta T cell differentiation GO:0045588: positive regulation of gamma-delta T-cell differentiation --> positive regulation of gamma-delta T cell differentiation GO:0045589: regulation of regulatory T-cell differentiation --> regulation of regulatory T cell differentiation GO:0045590: negative regulation of regulatory T-cell differentiation --> negative regulation of regulatory T cell differentiation GO:0045591: positive regulation of regulatory T-cell differentiation --> positive regulation of regulatory T cell differentiation GO:0045592: regulation of ovarian cumulus cell differentiation --> regulation of cumulus cell differentiation GO:0045593: negative regulation of ovarian cumulus cell differentiation --> negative regulation of cumulus cell differentiation GO:0045594: positive regulation of ovarian cumulus cell differentiation --> positive regulation of cumulus cell differentiation GO:0045598: regulation of adipocyte differentiation --> regulation of fat cell differentiation GO:0045599: negative regulation of adipocyte differentiation --> negative regulation of fat cell differentiation GO:0045600: positive regulation of adipocyte differentiation --> positive regulation of fat cell differentiation GO:0045607: regulation of auditory hair cell differentiation --> regulation of auditory receptor cell differentiation GO:0045608: negative regulation of auditory hair cell differentiation --> negative regulation of auditory receptor cell differentiation GO:0045609: positive regulation of auditory hair cell differentiation --> positive regulation of auditory receptor cell differentiation GO:0045637: regulation of myeloid blood cell differentiation --> regulation of myeloid cell differentiation GO:0045638: negative regulation of myeloid blood cell differentiation --> negative regulation of myeloid cell differentiation GO:0045639: positive regulation of myeloid blood cell differentiation --> positive regulation of myeloid cell differentiation GO:0045697: regulation of synergid cell differentiation --> regulation of synergid differentiation GO:0045698: negative regulation of synergid cell differentiation --> negative regulation of synergid differentiation GO:0045699: positive regulation of synergid cell differentiation --> positive regulation of synergid differentiation GO:0046006: regulation of activated T-cell proliferation --> regulation of activated T cell proliferation GO:0046007: negative regulation of activated T-cell proliferation --> negative regulation of activated T cell proliferation GO:0046013: regulation of T-cell homeostatic proliferation --> regulation of T cell homeostatic proliferation GO:0046014: negative regulation of T-cell homeostatic proliferation --> negative regulation of T cell homeostatic proliferation GO:0046629: gamma-delta T-cell activation --> gamma-delta T cell activation GO:0046630: gamma-delta T-cell proliferation --> gamma-delta T cell proliferation GO:0046631: alpha-beta T-cell activation --> alpha-beta T cell activation GO:0046632: alpha-beta T-cell differentiation --> alpha-beta T cell differentiation GO:0046633: alpha-beta T-cell proliferation --> alpha-beta T cell proliferation GO:0046634: regulation of alpha-beta T-cell activation --> regulation of alpha-beta T cell activation GO:0046635: positive regulation of alpha-beta T-cell activation --> positive regulation of alpha-beta T cell activation GO:0046636: negative regulation of alpha-beta T-cell activation --> negative regulation of alpha-beta T cell activation GO:0046637: regulation of alpha-beta T-cell differentiation --> regulation of alpha-beta T cell differentiation GO:0046638: positive regulation of alpha-beta T-cell differentiation --> positive regulation of alpha-beta T cell differentiation GO:0046639: negative regulation of alpha-beta T-cell differentiation --> negative regulation of alpha-beta T cell differentiation GO:0046640: regulation of alpha-beta T-cell proliferation --> regulation of alpha-beta T cell proliferation GO:0046641: positive regulation of alpha-beta T-cell proliferation --> positive regulation of alpha-beta T cell proliferation GO:0046642: negative regulation of alpha-beta T-cell proliferation --> negative regulation of alpha-beta T cell proliferation GO:0046643: regulation of gamma-delta T-cell activation --> regulation of gamma-delta T cell activation GO:0046644: negative regulation of gamma-delta T-cell activation --> negative regulation of gamma-delta T cell activation GO:0046645: positive regulation of gamma-delta T-cell activation --> positive regulation of gamma-delta T cell activation GO:0046646: regulation of gamma-delta T-cell proliferation --> regulation of gamma-delta T cell proliferation GO:0046647: negative regulation of gamma-delta T-cell proliferation --> negative regulation of gamma-delta T cell proliferation GO:0046648: positive regulation of gamma-delta T-cell proliferation --> positive regulation of gamma-delta T cell proliferation GO:0046845: branch cell fate determination (sensu Insecta) --> branched duct epithelial cell fate determination (sensu Insecta) GO:0048137: spermatocyte cell division --> spermatocyte division GO:0048142: cystoblast cell division (sensu Insecta) --> cystoblast division (sensu Insecta) GO:0048235: male gametophyte sperm cell differentiation --> sperm cell differentiation (sensu Magnoliophyta) GO:0048321: axial mesoderm cell differentiation --> axial mesodermal cell differentiation GO:0048322: axial mesoderm cell fate commitment --> axial mesodermal cell fate commitment GO:0048323: axial mesoderm cell fate determination --> axial mesodermal cell fate determination GO:0048324: regulation of axial mesoderm cell fate determination --> regulation of axial mesodermal cell fate determination GO:0048325: negative regulation of axial mesoderm cell fate determination --> negative regulation of axial mesodermal cell fate determination GO:0048326: positive regulation of axial mesoderm cell fate determination --> positive regulation of axial mesodermal cell fate determination GO:0048327: axial mesoderm cell fate specification --> axial mesodermal cell fate specification GO:0048328: regulation of axial mesoderm cell fate specification --> regulation of axial mesodermal cell fate specification GO:0048329: negative regulation of axial mesoderm cell fate specification --> negative regulation of axial mesodermal cell fate specification GO:0048330: positive regulation of axial mesoderm cell fate specification --> positive regulation of axial mesodermal cell fate specification GO:0048333: mesoderm cell differentiation --> mesodermal cell differentiation GO:0048334: regulation of mesoderm cell fate determination --> regulation of mesodermal cell fate determination GO:0048335: negative regulation of mesoderm cell fate determination --> negative regulation of mesodermal cell fate determination GO:0048336: positive regulation of mesoderm cell fate determination --> positive regulation of mesodermal cell fate determination GO:0048337: positive regulation of mesoderm cell fate specification --> positive regulation of mesodermal cell fate specification GO:0048342: paraxial mesoderm cell differentiation --> paraxial mesodermal cell differentiation GO:0048343: paraxial mesoderm cell fate commitment --> paraxial mesodermal cell fate commitment GO:0048344: paraxial mesoderm cell fate determination --> paraxial mesodermal cell fate determination GO:0048345: regulation of paraxial mesoderm cell fate determination --> regulation of paraxial mesodermal cell fate determination GO:0048346: positive regulation of paraxial mesoderm cell fate determination --> positive regulation of paraxial mesodermal cell fate determination GO:0048347: negative regulation of paraxial mesoderm cell fate determination --> negative regulation of paraxial mesodermal cell fate determination GO:0048348: paraxial mesoderm cell fate specification --> paraxial mesodermal cell fate specification GO:0048349: regulation of paraxial mesoderm cell fate specification --> regulation of paraxial mesodermal cell fate specification GO:0048350: positive regulation of paraxial mesoderm cell fate specification --> positive regulation of paraxial mesodermal cell fate specification GO:0048351: negative regulation of paraxial mesoderm cell fate specification --> negative regulation of paraxial mesodermal cell fate specification GO:0048371: lateral mesoderm cell differentiation --> lateral mesodermal cell differentiation GO:0048372: lateral mesoderm cell fate commitment --> lateral mesodermal cell fate commitment GO:0048373: lateral mesoderm cell fate determination --> lateral mesodermal cell fate determination GO:0048374: regulation of lateral mesoderm cell fate determination --> regulation of lateral mesodermal cell fate determination GO:0048375: negative regulation of lateral mesoderm cell fate determination --> negative regulation of lateral mesodermal cell fate determination GO:0048376: positive regulation of lateral mesoderm cell fate determination --> positive regulation of lateral mesodermal cell fate determination GO:0048377: lateral mesoderm cell fate specification --> lateral mesodermal cell fate specification GO:0048378: regulation of lateral mesoderm cell fate specification --> regulation of lateral mesodermal cell fate specification GO:0048379: positive regulation of lateral mesoderm cell fate specification --> positive regulation of lateral mesodermal cell fate specification GO:0048380: negative regulation of lateral mesoderm cell fate specification --> negative regulation of lateral mesodermal cell fate specification GO:0048392: intermediate mesoderm cell differentiation --> intermediate mesodermal cell differentiation GO:0048393: intermediate mesoderm cell fate commitment --> intermediate mesodermal cell fate commitment GO:0048394: intermediate mesoderm cell fate determination --> intermediate mesodermal cell fate determination GO:0048395: regulation of intermediate mesoderm cell fate determination --> regulation of intermediate mesodermal cell fate determination GO:0048396: negative regulation of intermediate mesoderm cell fate determination --> negative regulation of intermediate mesodermal cell fate determination GO:0048397: positive regulation of intermediate mesoderm cell fate determination --> positive regulation of intermediate mesodermal cell fate determination GO:0048398: intermediate mesoderm cell fate specification --> intermediate mesodermal cell fate specification GO:0048399: regulation of intermediate mesoderm cell fate specification --> regulation of intermediate mesodermal cell fate specification GO:0048400: positive regulation of intermediate mesoderm cell fate specification --> positive regulation of intermediate mesodermal cell fate specification GO:0048401: negative regulation of intermediate mesoderm cell fate specification --> negative regulation of intermediate mesodermal cell fate specification GO:0048515: spermatid cell differentiation --> spermatid differentiation GO:0050798: activated T-cell proliferation --> activated T cell proliferation GO:0050852: T-cell receptor signaling pathway --> T cell receptor signaling pathway GO:0050853: B-cell receptor signaling pathway --> B cell receptor signaling pathway GO:0050855: regulation of B-cell receptor signaling pathway --> regulation of B cell receptor signaling pathway GO:0050856: regulation of T-cell receptor signaling pathway --> regulation of T cell receptor signaling pathway GO:0050859: negative regulation of B-cell receptor signaling pathway --> negative regulation of B cell receptor signaling pathway GO:0050860: negative regulation of T-cell receptor signaling pathway --> negative regulation of T cell receptor signaling pathway GO:0050861: positive regulation of B-cell receptor signaling pathway --> positive regulation of B cell receptor signaling pathway GO:0050862: positive regulation of T-cell receptor signaling pathway --> positive regulation of T cell receptor signaling pathway GO:0050863: regulation of T-cell activation --> regulation of T cell activation GO:0050864: regulation of B-cell activation --> regulation of B cell activation GO:0050868: negative regulation of T-cell activation --> negative regulation of T cell activation GO:0050869: negative regulation of B-cell activation --> negative regulation of B cell activation GO:0050870: positive regulation of T-cell activation --> positive regulation of T cell activation GO:0050871: positive regulation of B-cell activation --> positive regulation of B cell activation GO:0050872: white adipocyte differentiation --> white fat cell differentiation GO:0050873: brown adipocyte differentiation --> brown fat cell differentiation GO:0051132: NK T-cell activation --> NK T cell activation GO:0051133: regulation of NK T-cell activation --> regulation of NK T cell activation GO:0051134: negative regulation of NK T-cell activation --> negative regulation of NK T cell activation GO:0051135: positive regulation of NK T-cell activation --> positive regulation of NK T cell activation GO:0051136: regulation of NK T-cell differentiation --> regulation of NK T cell differentiation GO:0051137: negative regulation of NK T-cell differentiation --> negative regulation of NK T cell differentiation GO:0051138: positive regulation of NK T-cell differentiation --> positive regulation of NK T cell differentiation GO:0051140: regulation of NK T-cell proliferation --> regulation of NK T cell proliferation GO:0051141: negative regulation of NK T-cell proliferation --> negative regulation of NK T cell proliferation GO:0051142: positive regulation of NK T-cell proliferation --> positive regulation of NK T cell proliferation New definitions for biological_process ontology terms (11 new definitions) GO:0007407, neuroblast activation GO:0008347, glial cell migration GO:0009585, red, far-red light phototransduction GO:0009588, UV-A, blue light phototransduction GO:0045058, T cell selection GO:0045059, positive thymic T cell selection GO:0045060, negative thymic T cell selection GO:0045061, thymic T cell selection GO:0045062, extrathymic T cell selection GO:0045067, positive extrathymic T cell selection GO:0045068, negative extrathymic T cell selection New term merges in biological_process ontology GO:0001679 has been merged into GO:0001841, neural tube formation GO:0006492 has been merged into GO:0006491, N-glycan processing GO:0042061 has been merged into GO:0045836, positive regulation of meiosis GO:0046652 has been merged into GO:0030217, T cell differentiation Term movements in biological_process ontology: Terms movements under GO Slim term 'development ; GO:0007275' + GO:0030097, hemopoiesis + GO:0035166, post-embryonic hemopoiesis + GO:0035172, hemocyte proliferation (sensu Arthropoda) + GO:0035206, regulation of hemocyte proliferation (sensu Arthropoda) + GO:0035207, negative regulation of hemocyte proliferation (sensu Arthropoda) + GO:0035208, positive regulation of hemocyte proliferation (sensu Arthropoda) Terms movements under GO Slim term 'physiological process ; GO:0007582' + GO:0007407, neuroblast activation Terms movements under GO Slim term 'morphogenesis ; GO:0009653' - GO:0001779, natural killer cell differentiation - GO:0001865, NK T cell differentiation - GO:0001923, B-1 B cell differentiation - GO:0001924, regulation of B-1 B cell differentiation - GO:0001925, negative regulation of B-1 B cell differentiation - GO:0001926, positive regulation of B-1 B cell differentiation - GO:0007516, hemocyte development - GO:0030097, hemopoiesis - GO:0030098, lymphocyte differentiation - GO:0030099, myeloid cell differentiation - GO:0030183, B cell differentiation - GO:0030217, T cell differentiation - GO:0030218, erythrocyte differentiation - GO:0030219, megakaryocyte differentiation - GO:0030220, platelet formation - GO:0030221, basophil differentiation - GO:0030222, eosinophil differentiation - GO:0030223, neutrophil differentiation - GO:0030224, monocyte differentiation - GO:0030225, macrophage differentiation - GO:0030316, osteoclast differentiation - GO:0030851, granulocyte differentiation - GO:0030852, regulation of granulocyte differentiation - GO:0030853, negative regulation of granulocyte differentiation - GO:0030854, positive regulation of granulocyte differentiation - GO:0035099, hemocyte migration (sensu Arthropoda) - GO:0035162, embryonic hemopoiesis - GO:0035163, embryonic hemocyte differentiation (sensu Arthropoda) - GO:0035164, embryonic plasmatocyte differentiation - GO:0035165, embryonic crystal cell differentiation - GO:0035166, post-embryonic hemopoiesis - GO:0035172, hemocyte proliferation (sensu Arthropoda) - GO:0035206, regulation of hemocyte proliferation (sensu Arthropoda) - GO:0035207, negative regulation of hemocyte proliferation (sensu Arthropoda) - GO:0035208, positive regulation of hemocyte proliferation (sensu Arthropoda) - GO:0042093, T-helper cell differentiation - GO:0042386, hemocyte differentiation (sensu Arthropoda) - GO:0042387, plasmatocyte differentiation - GO:0042492, gamma-delta T cell differentiation - GO:0042688, crystal cell differentiation - GO:0042689, regulation of crystal cell differentiation - GO:0042690, negative regulation of crystal cell differentiation - GO:0042691, positive regulation of crystal cell differentiation - GO:0043011, dendritic cell differentiation - GO:0045058, T cell selection - GO:0045059, positive thymic T cell selection - GO:0045060, negative thymic T cell selection - GO:0045061, thymic T cell selection - GO:0045062, extrathymic T cell selection - GO:0045063, T-helper 1 cell differentiation - GO:0045064, T-helper 2 cell differentiation - GO:0045065, cytotoxic T cell differentiation - GO:0045066, regulatory T cell differentiation - GO:0045067, positive extrathymic T cell selection - GO:0045068, negative extrathymic T cell selection - GO:0045577, regulation of B cell differentiation - GO:0045578, negative regulation of B cell differentiation - GO:0045579, positive regulation of B cell differentiation - GO:0045580, regulation of T cell differentiation - GO:0045581, negative regulation of T cell differentiation - GO:0045582, positive regulation of T cell differentiation - GO:0045583, regulation of cytotoxic T cell differentiation - GO:0045584, negative regulation of cytotoxic T cell differentiation - GO:0045585, positive regulation of cytotoxic T cell differentiation - GO:0045586, regulation of gamma-delta T cell differentiation - GO:0045587, negative regulation of gamma-delta T cell differentiation - GO:0045588, positive regulation of gamma-delta T cell differentiation - GO:0045589, regulation of regulatory T cell differentiation - GO:0045590, negative regulation of regulatory T cell differentiation - GO:0045591, positive regulation of regulatory T cell differentiation - GO:0045610, regulation of hemocyte differentiation - GO:0045611, negative regulation of hemocyte differentiation - GO:0045612, positive regulation of hemocyte differentiation - GO:0045613, regulation of plasmatocyte differentiation - GO:0045614, negative regulation of plasmatocyte differentiation - GO:0045615, positive regulation of plasmatocyte differentiation - GO:0045619, regulation of lymphocyte differentiation - GO:0045620, negative regulation of lymphocyte differentiation - GO:0045621, positive regulation of lymphocyte differentiation - GO:0045622, regulation of T-helper cell differentiation - GO:0045623, negative regulation of T-helper cell differentiation - GO:0045624, positive regulation of T-helper cell differentiation - GO:0045625, regulation of T-helper 1 cell differentiation - GO:0045626, negative regulation of T-helper 1 cell differentiation - GO:0045627, positive regulation of T-helper 1 cell differentiation - GO:0045628, regulation of T-helper 2 cell differentiation - GO:0045629, negative regulation of T-helper 2 cell differentiation - GO:0045630, positive regulation of T-helper 2 cell differentiation - GO:0045637, regulation of myeloid cell differentiation - GO:0045638, negative regulation of myeloid cell differentiation - GO:0045639, positive regulation of myeloid cell differentiation - GO:0045640, regulation of basophil differentiation - GO:0045641, negative regulation of basophil differentiation - GO:0045642, positive regulation of basophil differentiation - GO:0045643, regulation of eosinophil differentiation - GO:0045644, negative regulation of eosinophil differentiation - GO:0045645, positive regulation of eosinophil differentiation - GO:0045646, regulation of erythrocyte differentiation - GO:0045647, negative regulation of erythrocyte differentiation - GO:0045648, positive regulation of erythrocyte differentiation - GO:0045649, regulation of macrophage differentiation - GO:0045650, negative regulation of macrophage differentiation - GO:0045651, positive regulation of macrophage differentiation - GO:0045652, regulation of megakaryocyte differentiation - GO:0045653, negative regulation of megakaryocyte differentiation - GO:0045654, positive regulation of megakaryocyte differentiation - GO:0045655, regulation of monocyte differentiation - GO:0045656, negative regulation of monocyte differentiation - GO:0045657, positive regulation of monocyte differentiation - GO:0045658, regulation of neutrophil differentiation - GO:0045659, negative regulation of neutrophil differentiation - GO:0045660, positive regulation of neutrophil differentiation - GO:0045670, regulation of osteoclast differentiation - GO:0045671, negative regulation of osteoclast differentiation - GO:0045672, positive regulation of osteoclast differentiation - GO:0046632, alpha-beta T cell differentiation - GO:0046637, regulation of alpha-beta T cell differentiation - GO:0046638, positive regulation of alpha-beta T cell differentiation - GO:0046639, negative regulation of alpha-beta T cell differentiation - GO:0051136, regulation of NK T cell differentiation - GO:0051137, negative regulation of NK T cell differentiation - GO:0051138, positive regulation of NK T cell differentiation Terms movements under GO Slim term 'cell organization and biogenesis ; GO:0016043' + GO:0043131, enucleation New terms in cellular_component ontology (11 new terms) GO:0031410 GO:0005737 MAH D 1035336 cytoplasmic vesicle GO:0031411 GO:0005737 MAH D 1171962 gas vesicle GO:0031414 GO:0005737 MAH D 1200778 N-terminal protein acetyltransferase complex GO:0031415 GO:0005737 MAH D 1200778 NatA complex GO:0031416 GO:0005737 MAH D 1200778 NatB complex GO:0031417 GO:0005737 MAH D 1200778 NatC complex GO:0031421 GO:0005622 MAH D 1202745 invertasome GO:0031422 GO:0005622 MAH D 1202787 RecQ helicase-Topo III complex GO:0031428 GO:0005730 MAH D 1151181 box C/D snoRNP complex GO:0031429 GO:0005730 MAH D 1151181 box H/ACA snoRNP complex GO:0043384 GO:0005886 JL D 1156207 pre-T cell receptor complex Term name changes in cellular_component ontology GO:0008372: cellular_component unknown --> cellular component unknown GO:0016023: cytoplasmic vesicle --> cytoplasmic membrane-bound vesicle GO:0019815: B-cell receptor complex --> B cell receptor complex GO:0019816: B-cell receptor accessory molecule complex --> B cell receptor accessory molecule complex GO:0042101: T-cell receptor complex --> T cell receptor complex GO:0042105: alpha-beta T-cell receptor complex --> alpha-beta T cell receptor complex GO:0042106: gamma-delta T-cell receptor complex --> gamma-delta T cell receptor complex GO:0043005: neuronal cell projection --> neuron projection GO:0043075: pollen germ cell nucleus --> sperm cell nucleus (sensu Magnoliophyta) Term movements in cellular_component ontology: Terms movements under GO Slim term 'intracellular ; GO:0005622' + GO:0031234, extrinsic to internal side of plasma membrane New terms in molecular_function ontology (15 new terms) GO:0031402 GO:0005488 MAH D 1198232 sodium ion binding GO:0031403 GO:0005488 MAH D 1198232 lithium ion binding GO:0031404 GO:0005488 MAH D 1198232 chloride ion binding GO:0031405 GO:0005488 MAH D 1198280 lipoic acid binding GO:0031406 GO:0005488 MAH D 1198280 carboxylic acid binding GO:0031409 GO:0005488 MAH D 1198282 pigment binding GO:0031418 GO:0005488 MAH D 1201363 L-ascorbic acid binding GO:0031419 GO:0005488 MAH D 1201363 cobalamin binding GO:0031420 GO:0005488 MAH D 1202743 alkali metal ion binding GO:0031423 GO:0005515 MAH D 1202742 hexon binding GO:0043364 GO:0003824 JL D 1150045 catalysis of free-radical formation GO:0043365 GO:0003824 JL D 1150045 [formate-C-acetyltransferase]-activating enzyme GO:0043394 GO:0005515 JL D 1205528 proteoglycan binding GO:0043395 GO:0005515 JL D 1205528 heparan sulfate proteoglycan binding GO:0048551 GO:0030234 JIC D 1205241 metalloenzyme inhibitor activity Term name changes in molecular_function ontology GO:0004892: B-cell receptor activity --> B cell receptor activity GO:0004894: T-cell receptor activity --> T cell receptor activity GO:0005554: molecular_function unknown --> molecular function unknown GO:0030372: high molecular weight B-cell growth factor receptor binding --> high molecular weight B cell growth factor receptor binding GO:0030373: high molecular weight B-cell growth factor receptor activity --> high molecular weight B cell growth factor receptor activity GO:0042096: alpha-beta T-cell receptor activity --> alpha-beta T cell receptor activity GO:0042099: gamma-delta T-cell receptor activity --> gamma-delta T cell receptor activity GO:0042608: T-cell receptor binding --> T cell receptor binding GO:0043337: CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase --> CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity New definitions for molecular_function ontology terms (19 new definitions) GO:0004033, aldo-keto reductase activity GO:0005483, soluble NSF attachment protein activity GO:0005484, SNAP receptor activity GO:0008905, mannose-phosphate guanylyltransferase activity GO:0008969, phosphohistidine phosphatase activity GO:0008991, serine-type signal peptidase activity GO:0009003, signal peptidase activity GO:0009049, aspartic-type signal peptidase activity GO:0016848, carbon-halide lyase activity GO:0016854, racemase and epimerase activity GO:0016855, racemase and epimerase activity, acting on amino acids and derivatives GO:0016856, racemase and epimerase activity, acting on hydroxy acids and derivatives GO:0016857, racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016859, cis-trans isomerase activity GO:0016866, intramolecular transferase activity GO:0016867, intramolecular transferase activity, transferring acyl groups GO:0016868, intramolecular transferase activity, phosphotransferases GO:0016869, intramolecular transferase activity, transferring amino groups GO:0050486, intramolecular transferase activity, transferring hydroxy groups Term movements in molecular_function ontology: Terms movements under GO Slim term 'binding ; GO:0005488' - GO:0005102, receptor binding Terms movements under GO Slim term 'protein binding ; GO:0005515' + GO:0005102, receptor binding - GO:0017162, aryl hydrocarbon receptor binding - GO:0042809, vitamin D receptor binding - GO:0042974, retinoic acid receptor binding - GO:0046965, retinoid X receptor binding - GO:0046966, thyroid hormone receptor binding SourceForge items closed this month: SF id Resolution SF item title GO ids added, if any 1012888 Fixed mitotic cohesin complex [none] 1107867 Fixed missing parent internal side of plasma membrane [none] 1111856 Fixed Obsolete GO:0042061, since GO:0045836 exists? [none] 1150045 Accepted free radical generation GO:0043364-43365 1150233 Accepted def for snRNP term, GO:0030532 [none] 1150646 Accepted defs for other RNP terms: GO:0005732, GO:0030531 [none] 1151181 Accepted specific snoRNP complex terms GO:0031428-31429 1156207 Accepted Revision of T-cell differentiation node GO:0043366-43384 1156764 Fixed missing activity [none] 1169020 Works For Me EC 3.2.1.89 [none] 1171962 Accepted gas vasicle terms GO:0031411-31413 1174124 Fixed process in function: 6484 : protein cysteine-thiol oxidation [none] 1178763 None GO ids with number of genes in each [none] 1185117 Works For Me secretory pathway missing parentage? [none] 1185832 Rejected morphogenesis terms redefined [none] 1186080 Accepted sporocyte morphogenesis GO:0048533 1189818 Accepted ntr:chloroplast RNA processing GO:0031425-31426 1191014 Accepted chromatin silencing vs heterochromatin formation [none] 1191240 Accepted Regulation Terms for GO:0016567 GO:0031396-31401 1191648 Fixed def required N-linked glycoprotein maturation [none] 1192419 Accepted Changes to GO for alignment with cell ontology GO:0043339-43363 1195441 Fixed GO:0005178 integrin binding parentage [none] 1196601 Accepted add synonym [none] 1198160 Fixed RAN-binding protein [none] 1198232 Accepted Children of metal ion binding GO:0046872 GO:0031402-31404 1198280 Accepted New term: 'lipoic acid binding’ GO:0031405-31406 1198282 Accepted pigment binding GO:0031409 1198284 Fixed Phytochrome signaling pathway [none] 1198287 Accepted New Term: oxylipin biosynthesis GO:0031407-31408 1198288 Accepted New Term: 'response to methotrexate’ 1198289 Accepted ‘metalloenzyme inhibitor activity’ GO:0048551-48554 1198936 Rejected term merge? oluble NSF attachment protein/SNAP receptor? [none] 1199037 Works For Me query phosphatidylinositol transporter activity [none] 1200109 Accepted merge "neural tube formation" and "neurulation" [none] 1200778 Accepted acetyltransferase complex GO:0031414-31417 1201306 Accepted protein O-mannosyltransferase [none] 1201363 Accepted vitamin binding GO:0031418-31419 1202738 Accepted Keratinization GO:0031424 1202742 Accepted hexon binding GO:0031423 1202743 Accepted alkali metal ion binding GO:0031420 1202745 Accepted invertasome, nucleoprotein structure GO:0031421 1202746 Accepted atom binding [none] 1202748 Accepted synonym: ammonia transport [none] 1202787 Accepted ntr: RecQ helicase-Topo III complex GO:0031422 1203520 Accepted larval development [none] 1203547 Accepted synonym for IkappaB kinase complex [none] 1203713 Accepted organogenesis def [none] 1203722 Rejected Obsolete aldo-keto reductase activity [none] 1205241 Accepted regulation of pinocytosis GO:0048548-48560 1205528 Accepted proteoglycan binding ; GO: NEW GO:0043394-43395 1205888 Accepted regulation of protein binding GO:0043393 1206995 Accepted spelling errors? [none] 1207105 Accepted negative regulation of DNA binding GO:0043388 GO:0043392 1207904 Accepted Phytochrome chromophore biosynthesis GO:0048543 1208320 Rejected biosynthesis def [none] 1209738 Accepted response to steroid hormone stimulus GO:0048545 1209901 Duplicate germination [none] 680137 Fixed hemopoiesis [none] 913164 Out of Date protein (degradation) tagging activity alternatives? [none] 953912 Accepted photosynthesis defs [none] 991948 Out of Date children of signal transduction [none] Statistics: biological_process: 9706 terms, 97.1% defined (9424 terms defined) cellular_component: 1644 terms, 94.5% defined (1554 terms defined) molecular_function: 7502 terms, 90.9% defined (6818 terms defined) Total: 18852 terms, 94.4% defined (17796 terms defined) Term errors GO:0031382, mating projection biogenesis - moved from cellular_component ontology to biological_process.