<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCS7</accession>
    <name>A0A010YCS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase chain I-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441333.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_549543_0_0_0"/>
    <dbReference type="OrthoDB" id="214158at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="507" mass="54557" checksum="29F0D9D44FBF7379" modified="2014-06-11" version="1">MIRVEISKCVGCKACEQVCPSGAIRVVDRKAVVNDNCVHCVTCIKYCKPGAISEDAVAENTLLCRNCGVKCRIPEGKEGACKRFRNENGGLALVRPLQIPTNTEITPEKTAIMKPVVSAVGAGAAYPDYKPAPYIVTEKRDDFDVVTVVTEAPVSYSSMMVKIDTNAHIGDEGALVRRSGRVVGIVTTEQYGSHILILGGVNKVKGPDGMYVVKTMAELGNKEKVTLTVDNGCTLELQVGEHPVINGVVDDKMRVGCGGACCGLFARSLAPLIDEAIILDHHITGLFTQHPAGAEQKPYSGVTPVGRLATNGRYFFEHGDGWGGTNIKDPIEAIRNIDMNIARPGMKILVAETTWRKIALFEVSSEGKPVPVAIPAELEAFRKMAAGCCEDSRVSAMYYAGVGGSARAGVTVDPIQITKAVHRGDANLTIAGAPTYLMPGGGITFLADVEKMIDHPFNYTASPAVLAPIEYTMTVENYEKIKGHVHAMRTKEDVLKEGRYEFTELKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCU5</accession>
    <name>A0A010YCU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase, beta-lactamase superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441343.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036012_0_0_0"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="273" mass="29945" checksum="CE57B1869617BB5E" modified="2014-06-11" version="1">MLDLTILTDNNTIIDRYYLGEPGLSFWLECGGKKFLFDTGYSDVFIRNAALMGIELTRMDGLIYSHGHNDHTWGTHSLVALFDRLAVERRPLLVAHPLAFENKVHGRLTIGVMMGAEALGNYFELALSAEPRELAPRLWWLGEIPAAVTPRRAVGKIKDSRGERGDYCLDDSALAYAGEDGLVIITGCSHSGICNIIERARDVTGERRVADVVGGFHLLSCSGGEMAEISAYMKMVGVTRLHPCHCTDFAAKAALARDFSVAEGGVGLRLNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCV6</accession>
    <name>A0A010YCV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytidylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709280.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.190"/>
    <dbReference type="HOGENOM" id="CLU_065155_3_1_0"/>
    <dbReference type="OrthoDB" id="1962890at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="202" mass="23296" checksum="A3BF9E311C31800A" modified="2014-06-11" version="1">MEKRIITISRQFGSGGHEVGMRLAKRLGVKFYDKELVDLLAKDGKYDVDFIEANEEKCSPPMCPIMPGFAMPVFYQDLPSDLIYKGQSKLIRSLAERGPCVVVGRCADYILRNMNPVDCFIYGSLDERINRKMSMIPEGLDFTREEIKKRIIDVDKKRAKYYEFYADRRWGKMEDYDLCISTDNIGVDGAVETIMAYLEHCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD19</accession>
    <name>A0A010YD19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytosine/adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0226</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441401.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107695_0_0_0"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="13"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="182" mass="20646" checksum="1FA1917801395F92" modified="2014-06-11" version="1">MNKPQLILKAIKESLIPLTEKEVAAGNHVFGGLVLDKESCQVITAGSNNRRENPIYHGEIDTIRRFFAAPGHPDPAKCIFVASHDPCSMCISAISWAGFHEIWVLFGYDDVEKEFGMPVDLMMYKELFGAEGATDDNKFFRKYYLKKEAAKQENAAELRKEIAEIEKLYGEMRVEDFDYPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDA1</accession>
    <name>A0A010YDA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441473.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.325"/>
    <dbReference type="HOGENOM" id="CLU_065103_0_1_0"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="271" mass="32105" checksum="D8B4DC2025F33A30" modified="2014-06-11" version="1">MKNYYKINEISKLYGIGVDSLRYYERLGILRPRRDVNGYRLYSLKEMYKLNIIRDLRRLDFSMAQIKEYLADQSVANTLELLRREQALLAERLRELLTREELIKERIAVLDNARNIRTGVFTVKDLPDRFCVRLSEHIARDEEMDFAVKKLHRQHEEKIRDFGNQIIGAFPSMENLRNGISNVYEAVFFILERRSPDYDFILPAGEYLSYFYGGGYGQNAKRMEELLAYAKEEGLRLSGEPFEMYEIDNRDTVREEEFLTEIQVRVAAPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDC2</accession>
    <name>A0A010YDC2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclophil_like2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484807.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099043_0_1_0"/>
    <dbReference type="OrthoDB" id="1961657at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041183">
        <property type="entry name" value="Cyclophilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18050">
        <property type="entry name" value="Cyclophil_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457847" description="Cyclophil_like2 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclophil_like2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="147" mass="15397" checksum="C6F26FD28E43BA41" modified="2014-06-11" version="1">MKKTTAAALLMLAFSAICCLTGDAGAAEKILLTAGGKSFTAELNDGPAAAALLKKMPFTLEMKDLNENEKFAYLDGALPAKASAPGTIRAGDIMLFGADCLVVFYKTFPTAYSYTPLGKIEGAETVSALSGKDGIKITFSRNKTKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDG3</accession>
    <name>A0A010YDG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441535.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067057_1_2_0"/>
    <dbReference type="OrthoDB" id="1307509at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458768" evidence="1">
        <location>
            <begin position="28"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="2">
        <location>
            <begin position="33"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="2">
        <location>
            <begin position="109"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="175" mass="19587" checksum="4457C00C69AB1FD6" modified="2014-06-11" version="1">MKKKIFQYAGVLFCAAYLIFGMTPACSEAVSLIGEERAKQIAFQHAGASESGARILKLGLDNDHEHTEYEIDFVFGDFKYEYGIDAVSGAVRKFGKKAGYGTAAHAQYIGPQAAEKIAFDHAKVKRGDVLYLRTKLDHDDGMVKYEVKFFCNGLKYEYDIEAKTGQILEFEQDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDM6</accession>
    <name>A0A010YDM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484821.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109336_0_0_0"/>
    <dbReference type="OrthoDB" id="1891112at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019271">
        <property type="entry name" value="DUF2284_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10050">
        <property type="entry name" value="DUF2284"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="181" mass="20473" checksum="3ABE73F374961C66" modified="2014-06-11" version="1">MNYSVIAYSTVCDVEDFVASCVDVPKFLGFCRECHNYGNNWMCPPFDFDPLDIWRSYEKIKLFGLRMTPAREGGEGKSAAERAKEIISKEKRRLIGELLEEEKKIPGSLSFFAGSCELCPVCAKVTNEPCRRPAMARHSIESLGANVSLAMKRYLGLDILWIKDDRLPEYLTLVAALLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDS4</accession>
    <name>A0A010YDS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2408046_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="92" mass="10099" checksum="A64D4026548E24DE" modified="2014-06-11" version="1">MSGLKQRVLEAISETDDVLLDVLCGNCPAKYLEKGATEGGLAIEPDEWTCPCSFEYGDPGCERCGDYKRIEELAGKLADEMERMEGAVSDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDS7</accession>
    <name>A0A010YDS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062999_3_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="161"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="307" mass="34990" checksum="B6DA621F6CFB390D" modified="2014-06-11" version="1">MMYTASEALRSSVPNLMEYRDEAAMKRQHAEMWQEVLVWMNKRFKDVRPEDLYDQQLLSLHAAMCMEEDCKYCIDVSQCPHSRAALVVCEEQERGRRAFMVRAKVCDFLSQHRQEARRHDLLEESGIPKARRGNSFQAFDTLGGSMVLQATKAKAQECFEKGRGLVLGGPVGCGKTHLAIAMGLAAVEQGQSVRFFLLPDLLEDLRSAMFDHREELLSEVKSCGWLILDDAGTERSTDWNDERLFVMIDHRCNHNLPVVVTTNAVGEDGLRRILDGDRGARTFSRLMGMTEQAWMVGVPDYRRKGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE22</accession>
    <name>A0A010YE22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rubrerythrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710299.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.618"/>
    <dbReference type="HOGENOM" id="CLU_095256_1_0_0"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01041">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003251">
        <property type="entry name" value="Rubrerythrin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02915">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="1">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="162" mass="17678" checksum="02BE5AFEA77613B0" modified="2014-06-11" version="1">MSTTQENFATAFAGESQANRKYLMFAEQAEKDGFAGIAKLFRATAAAETIHAFAEFKAKGGVGTTADNLQAGIDGETYEFSEMYPPMIEQAKAEGNKEAARIFHYANEAEKVHAKLYKEALADMSNTDSDYYLCPICGFIHKGETSSPCPICGAKPSIFQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE84</accession>
    <name>A0A010YE84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator with C-terminal CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441902.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.696"/>
    <dbReference type="HOGENOM" id="CLU_066192_18_4_0"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="39"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="98" mass="10719" checksum="BFF6DC0C33309FF3" modified="2014-06-11" version="1">MSEKAISPKGRSWSEVREQILTPEERGVSNLRVAMMVELAAARAEKGISQKKLEALSGVKQPVIARMEKGYTSPQLDTVLKVLAPLGKTLYIGDLPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEB2</accession>
    <name>A0A010YEB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0682</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441931.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.727"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="282" mass="30870" checksum="A7EC2F838AD2296E" modified="2014-06-11" version="1">MADTILKTEDVMIKFGGLTAVSGFTIEVERGSITSLIGPNGAGKTTCFNIITGFYKPTSGRVIFDGCDITPLEPHIVCKSGVARTFQNIRLFTGGTVLQNVMTACWVRQRAPWWSAPLYLPLFLREEREIRGRSMELLEAVGLDKLAGEVATGLPYGAQRRLEIARALATNPKLLLLDEPAAGMNPQESQDLMDFIRSIRDKFDVTILMIEHDMKVVMGVSEWIRVLDYGQLIAEGTPADIRSNPKVIEAYLGKDAARAGESPARRAASGGRPCEGEESDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEE5</accession>
    <name>A0A010YEE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441962.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.762"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_0"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="39"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="396" mass="43857" checksum="D4648B805D59E833" modified="2014-06-11" version="1">MTTKVKFPNSRMASISMSGGIREILTRADELERGGRSIVHMEIGRPDFDSPKCAKDRAIRALNEGNVHYTDMAGAYDLRCAVADKYRRENGMDYVEADKNVVITNGAMEALTATFLTLFEPGDEVIVPAPYFSAYADEIAIANAVLVPVPTRMENGFRLQAEELKKALSPKTKAILINSPNNPSGAVLTRKDLEAIAVFAIENDLWVISDECYEKFLYDGEHVSIASFPGMEERTVTVAAASKTWSMTGWRIGWVVAPASMRPYVNKCHQNLTTCANSFAQAGVVEAFANADGDVTAMVSEYKRRRDMVVKWLNDIEGFEAITPAGAFYAFPRISRLGMDGFKFCSWLLEEAGVSTVPGEVFGMQGHIRLAYCRSYDYIEEGMKRIKEAVEGRPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEN2</accession>
    <name>A0A010YEN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dissimilatory sulfite reductase (Desulfoviridin), alpha/beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0793</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_11_4_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="57" mass="5595" checksum="500921C6C7AC0C82" modified="2014-06-11" version="1">MAKASVDQSVCVGCEACVGVCPTSAISMEDGKAHVDGDTCVECGACVATCPVSAISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF49</accession>
    <name>A0A010YF49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mevalonate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442273.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041895_0_0_0"/>
    <dbReference type="OrthoDB" id="1383921at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458822" evidence="1">
        <location>
            <begin position="23"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="516" mass="58386" checksum="C2805A77E5F44DF7" modified="2014-06-11" version="1">MKKFMAVLAMVAVVAFAAPALAATNPFMDVPQGHWAYDAVGLLASRGIVSGYPDGAFKGAQPATRYEMASVVARALVAIDADKASKQDLELLKKLVMEFKDELDALGVKVDKLDKRVAVLEDGIGGWKIRGNFRFDAKFGGSDNDVNNYTANGEDNEFTKSRFRLFLTKQIDENTYFYAQYRTGSDSAGNKDGRGDLQHMRWSHLYVNTKLPYDVDLRVGRFAVDFEDEYGLYTDNDSIFGDYRTDGFQLSKKWNSFKATAIVGRNDNWGNDYAMDGTLGEGTYMNYALDLNWRPNEKFMLGATGYWFQEDSNFVDGDYDVNVYGFYAGFKFTPAVELKGIYYFQDLGSDVMTYGYGGVRAGDTEDSPKAWKAILDIKQDLLKFTGLWIEYSQQDNTFLGYENRYSIGGGNGNYDYVGRNMMYADPFGTSKWWFVKADQKWNDKWSSFVRFANVDYDTDYLDDATEWGLGVGYQYTPAIYFELAYDQVDHGDTNLLGFAGTQGKDHVVRFRTNVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF68</accession>
    <name>A0A010YF68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="8" type="ORF">Cloev_0995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1064"/>
    <dbReference type="HOGENOM" id="CLU_098841_0_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="121" mass="13386" checksum="89760723101819A7" modified="2014-06-11" version="1">MINNRSRNEMRELRHRRLRKHLSGTGERPRLAVFGSLKHMSAQIIDDEKGNTLVSASTIQDKFDDVKGTGNQEAAKAVGKLIAERALAHGITEVVFDRGGHVYHGRVKALAEAAREAGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF72</accession>
    <name>A0A010YF72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="10" type="ORF">Cloev_1000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442294.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1069"/>
    <dbReference type="HOGENOM" id="CLU_032354_1_2_0"/>
    <dbReference type="OrthoDB" id="1491686at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADK_lid" evidence="9">
        <location>
            <begin position="127"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="6">
        <location>
            <begin position="126"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="213" mass="22888" checksum="7A85B0C7EE44DF93" modified="2014-06-11" version="1">MRIILLGAPGAGKGTQADSIKGKYPVAHISTGDILRANVKAGSELGKSAKEYMDAGKLVPDEVIIGMMEKRLQEADCKDGFLLDGFPRTIGQAEALDVMLAKLGIKLDAVVSLAIDDDTVVGRLTARRVCRQCGEIYNTVLKPAAKEGVCDKCGGEVIQRDDDKESVIRNRLSVFHEQTSPLIDYYGDKGLLVTVDATGGKDAVLKILEQRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFF0</accession>
    <name>A0A010YFF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dimethyladenosine transferase (RRNA methylation)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_1113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711231.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1186"/>
    <dbReference type="HOGENOM" id="CLU_041220_0_0_0"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="7">
        <location>
            <begin position="23"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="291" mass="32859" checksum="7C56F3789EACB275" modified="2014-06-11" version="1">MADKRHFIHNTDIGQNFLIDRGVVEFILKRSEPAAGDVVLEIGPGDGILTRGLLTTPLAALYSVEVDDRLRDGIERIAAHDGRYRCFWGDAVRFDYVRELPEMPAKIIANLPYHITTPLMWAFLEQLVPDKTDYMLLMVQLESAERIASPAGHRERSPLGITVEAMGSAEIVRKIPPSAFNPQPRVNSALIEIKIERNRELANDRTWRGLLARSFTQRRKTLVNNWTAGYGGSGVTRETALEILAAHDLRATARAEELPLEKWFELAKVPEFHLKNKKSGERINKDVVESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS37</accession>
    <name>A0A010YS37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HIT family hydrolase, diadenosine tetraphosphate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034444901.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.21"/>
    <dbReference type="HOGENOM" id="CLU_056776_1_2_0"/>
    <dbReference type="OrthoDB" id="1934382at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="28"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="123"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="18815" checksum="4B1C8A7843B3AB2D" modified="2014-06-11" version="1">MDKIFAPWRMQYILSNSDNNDPQEKGCIFCNFPKLDEDEKRLIVERGRYCFVIMNAYPYNPGHLMVVPYRHTADVTSLSAEEFGEMTALVQKSVKALTALMQPHGFNIGMNLGKVAGAGIDQHLHMHVVPRWNGDTNFMPVIGEVRVVSESLASAYSRLKAIWPTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS50</accession>
    <name>A0A010YS50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor eIF-1/SUI1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484741.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.41"/>
    <dbReference type="HOGENOM" id="CLU_1767131_0_0_0"/>
    <dbReference type="OrthoDB" id="2078610at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="5">
        <location>
            <begin position="81"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="147" mass="15601" checksum="D6C7C6746F7B02BC" modified="2014-06-11" version="1">MKEKKNKKLTEGEGFSLSRQGPLGISLGALLGAEKTAEPAVSDAADSGTETKKASPPPAREKTQTETKISKVSLRRERAGRGGKTVTIVMLPQDYRGDTAALAKDLRKALGCGSAMEEGKIVLQGDIMERVEAWFLKKGAAKVTKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS53</accession>
    <name>A0A010YS53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441222.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.47"/>
    <dbReference type="HOGENOM" id="CLU_022426_1_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="158"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="550" mass="62984" checksum="4D5FA610813D91A5" modified="2014-06-11" version="1">MRALGAKIIESLEQERAKKASSQTLLFEPSVEEAEEGICRYERPVEDGAYIKISDMVNEATIIEGPMNAAEKLYDLLGLDHIFKSSAREMGKVSLLKQALANTMAHPSSKRGMVQWLREACRSEVSVDRMYRLMDTLCEREETVKRIIKSQTEGLFASKPTLILFDATTLYYESFKEDGLRQCGYSKDAKFKETQIIMALAATTEGLPLWYEIFPGKTWEGDSIKSFVSDWRRNVYEESGGVVVADSGMLTKENMAKLNEEGLNYIVGARLKSMKKSEKAEILELSSYTSFTAPVHCFDEADSVSDTENKRILKYKVMKLEGGRNLLVTWDSKRAEKDACDREELLTRLEKKLNGSGKVKGKNLIGNRGTSRFLKVAEGENEASYERDTVKIEQDGKWDGLHGIMTDLPLGTEEEIREALSRYHSLWKIEESFRISKSDLKIRPMYHWTESRIRGHIALCYISFAMMRQLQKRLLLQQQDQMSVKRIREALLGETSVIIRDKSNGRRLRVPMEQTSEMKKINKVLGIKRTTVPREITSMVQYRNRYNSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS66</accession>
    <name>A0A010YS66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein, putative amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0053</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the creatininase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441235.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.62"/>
    <dbReference type="HOGENOM" id="CLU_055029_0_0_0"/>
    <dbReference type="OrthoDB" id="984747at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="243" mass="26797" checksum="0319A5A2A40DD786" modified="2014-06-11" version="1">MTWKEIEAERGEMIALIVSGSVEQHGPHLPTGTDLYIAMGMADRIASLPGAGDVAGRLVMLPPLFHTYAKESDGWRGTLNFDGNTLTFVVRDIIKGLFRQGIKKVVLLNGHLESYSFILEGIELAAEGRDDVRVMSVNWWDFIGDELISELFADRWPGWVAEHAALTETSIMLALYPDLVRADLADAGVIPKPLPYKIFPQPQEVRPPSGMYAPAEGASAEIGERLVSEVVKGLVPIIRERFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSE3</accession>
    <name>A0A010YSE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Selenium-dependent molybdenum hydroxylase system protein, YqeB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441335.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.167"/>
    <dbReference type="HOGENOM" id="CLU_082089_1_0_0"/>
    <dbReference type="OrthoDB" id="1072730at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017695">
        <property type="entry name" value="Se-dep_Mo_hydrolase_YqeB"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03309">
        <property type="entry name" value="matur_yqeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="265" mass="27899" checksum="F197A7D65E2820D4" modified="2014-06-11" version="1">MRNGKTAVVRGGGDLATGIIYRLWRVGYSVLALETALPLVVRRTVSVASAVFDGRAKVEDMSAVLIGSMKEYDPASDVIQVLVDPEGRSIREVKPDILVDAVMAKKNIGTTKDMAPTVIAVGPGFSAPGDVDAVIETKRGHTLGRVIRDGSAIPNTGVPGIIKGYGTERLLRAPADGYLLPVRKIGDEVSVGEVVGYVGGVEVCARVDGVLRGLIHPRVRVTNGLKIGDVDPRGDPSHCWSITDKALAIAGGVLEVIMSRDSNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSL5</accession>
    <name>A0A010YSL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441405.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.249"/>
    <dbReference type="HOGENOM" id="CLU_029779_0_0_0"/>
    <dbReference type="OrthoDB" id="1513550at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458145" evidence="2">
        <location>
            <begin position="23"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="658" mass="74240" checksum="85729B406CEA09A6" modified="2014-06-11" version="1">MLTFLIASLIFLLTMTSDNAFAADGLRFDVAVIGAGTGGSAAAIQAARMGMDVALIEESDWIGGQMTGAAVSTMDDVRRTRTGIYNEFITRVRDYYAMRNTPVNVCYWGSDTIAFEPWVGRKILTDMIKESGKVTLFLEARVLKVKTEKNRVVSAVIESGGEKTTVTAKVFIDATETGDFIPLTGARYRVGNSIAPKIDKESVIQDITYVAVVKKYPDGLPPELKLTKRPPGYEDYLPHFRKVITKDGDWWPGEYPFNVPVHNAYRAMPDTTNPDREKIDGGVSSTWPLITRTGVNWANDYPGRKYGEAGMSVKYLEDKKFRREAERRAMAETLAFIFYMQTELGLEDWSVDDRQGYGKYFSNNWQEWKEMPDEFSSVLIHFPPFPYVRESRRIVGVTTMTVKDVERDRVLRRMLKTNPDSIALGEYPTDIHGLREPQYLDRDLGERADEIPADSEWKGGLFQIPLGVLVPEKVDGLLAAEKNISVSRIVNGSTRLQPVTMLTGQAAGALAAESVRQNTAPRKVRPLDVQWRLLGAKDKLSLFNFDDVPVESLWWRGVELSVIYDYMDPASETIYGVDQEMHWLEVRDAFRRAFGRLEFPAREYEATVTLDEFSGWLRELFGADAERYKSVLERFSGGEVMKKGQLAAAVAEIKLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSQ3</accession>
    <name>A0A010YSQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RND family efflux transporter, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484799.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_1_0"/>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="78"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="42384" checksum="411559E9B92B1E8E" modified="2014-06-11" version="1">MQNAGDKKNFELTGRPRSAWIKIALVAAVVAAAACGCKIAAKETTAGGQAPAGEPLVTVTSVGTADVSSQPSEYVGRVEAIQYVQVKPQISGEIAKVCFKEGALVRAGDLLFQIEPAPYQATVELRRAELERARATLAEAEKYHARVTAADARAVSAADRDTAESNLLQGRAALSQAKASLRLAEIDLGYCRITSPITGKIGAAAFTKGNYVTPQSGALASIVQMDPIRVSYSLPDRDYLDQLELFKKQGPVYKTKLVLSNGTSFEAAGERDFEDNVVERQTGTVLVRLRYANGDGMLIPGGMVRVFARPAKSRAAAVVPQSAVMADGEGDYVYLLNADDTVRAARVALGREMGQMREVKEGLSAGQKVVVSGIQSLSPGVKVRVGDAVAAQADPDGKEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSS8</accession>
    <name>A0A010YSS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441463.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="145"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="252" mass="27780" checksum="6CBB0E974676F286" modified="2014-06-11" version="1">MAADQAKILIVDDDRELRELIAETLSEYGYDSRAAKNGAELFAALEREAFDLILLDIMMPGEDGLSLCRRLRAPGAPHSAVPIIFLTALKDTTDKVVGLEIGGDDYLCKPFHARELIARIRALLRRSSFSGETGRVGLVGSGEADSALIFGSWKLNVMARHLIDEEGVIVPLSAAEFRLLMLLLSHPQQVVTRDMIMDYLAERSLNIYDRSIDAQVSRLRAKLRDKGANPGLIRTMRGDGYMLAAPVRKGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT20</accession>
    <name>A0A010YT20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LAO/AO transport system ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709095.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.442"/>
    <dbReference type="HOGENOM" id="CLU_043725_2_2_0"/>
    <dbReference type="OrthoDB" id="1134430at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="PTHR23408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="379" mass="40948" checksum="2D0DBA83D155CC3A" modified="2014-06-11" version="1">MRKNFRPDWQPENAGAEFACSVMPGVPLASDCNAEARAAPPAKAKAVLTADDYARGILAGDRVMLSRAITVIESNAPKHFELGQEIIQKILPHSGKAMRIGITGVPGAGKSTFIEAFGTYLCGEGCKVAVLAVDPSSSLSKGSILGDKTRMENLAREKNAFIRPSPSGGSLGGVTRKSRETMLLCEAAGYDAVLVETVGVGQSETMVRSMVDYFLVVVITGAGDDLQGIKKGIIELADSILVNKADGDNKMKAMMARADYDQILHYLRPATEGWKTRAYTCSSITGEGIPEMWSVIKDFRENVTASGIFSKRRKEQTIEWVRAMTAEYLQNRISQNAELTKCREDIERKVIAGAITPTVAAKAVIGSMERLLFTATDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT31</accession>
    <name>A0A010YT31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709117.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.458"/>
    <dbReference type="HOGENOM" id="CLU_017584_5_2_0"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="238" mass="28182" checksum="A462E94E21515A2F" modified="2014-06-11" version="1">MTCESQFTLKSLREQVYDYLRIQMNEGRIRAGSFLNLNDISRELGMSRTPLRDALFQLESEGFITIFPRRGVVVNALTLEKIRNIYEMLGALESAVLVLVAVRFRESDAELMERYNQQMSKALDQNNFSVFYDANLKFHNVYLEMSDNAEMLHSIKIHKERLYDFPRNKTFVKEWELHSLEEHKTMIEMLRNHDFNSAADYIRDVHWSFSVQERFIRKYYFAKHLDLDLSEEGIGAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTA0</accession>
    <name>A0A010YTA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type sugar transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709617.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.549"/>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_0"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="267"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="539" mass="58541" checksum="EBA8634A330AB55D" modified="2014-06-11" version="1">MSEKAPLLRIENIGKDYFGNCVLQDVTFSLKEGEIMGLVGENGAGKSTLMNILFGMPVIHQTGGYTGKIVMDGEEVCFKDPTDALNAGIGMVHQEFSLIPGFSATENILLNRESTKYNPLVEVFGDRLKTLDRADMKKRAESAIRTLGVDLKADTLISEMSVGHKQFTEIAREIDRSKTRLLVLDEPTAVLAESEAEVLISALKALAGQGIAIIFISHRLQEIIELCDKFVVLRDGRVIKESPAANSSVRQIASWMVERKTDGAEDISAKERTRTIGGVLLKTEHLWVDMPGETVRDASLEIHEGEIFGIGGLAGQGKVGISNGIMGLCAAGGKVYLRGKEIVLNDPQASLKEGMAFVSEDRRGVGLLLKEGIDWNIAFTALQVQEKFLRSFLSGLVKWRDDRAIEKCTREYISSLKIRCTGPKQRAIELSGGNQQKVCLAKAFAVAPDILFVSEPTRGIDVGAKKLVLDTLREANEKHGTTIIMTSSELEELRSVCDRIAVVNEGTVSGILPAQSPAEEFGLMMLGHAGVGSPESQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTJ8</accession>
    <name>A0A010YTJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="8">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cloev_0629</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8 11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8 11">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710369.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.674"/>
    <dbReference type="HOGENOM" id="CLU_023296_1_1_0"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="PTHR11822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="12">
        <location>
            <begin position="9"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="94"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="9">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="9">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG78503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="45140" checksum="75A3D265F0DCA6DB" modified="2014-06-11" version="1">MAKIQMKTPLVEMDGDEMTRILWKQIKDTLILPFVDLKTEYYDLGLKHRDETDDKITVESAEATKKYGVAVKCATITPNAQRVEEYSLKKQWKSPNGTIRAILDGTVFRAPIMVKGVSPTVRTWKKPLTIARHAYGDIYKDVEMNIPCAGTLKMTFEPSDGDAAKRQEEVVFEYKGPGVAMAMHNLEKSISSFARACFKYALDTKQDLWFSTKDTISKKYDQTFKLIFEDVFEKEFKAGFEKEGITYFYTLIDDAVARVIRSEGGFIWACKNYDGDVMSDMVATAFGSLAMMTSVLVSPDGVYEYEAAHGTVTRHYYQHLEGKATSTNPMATIFAWSGALRKRGELDGIDELVKFADKLEKASIETIESGQMTKDLYAIAEIPNKKSLTSAEFLDAIAKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTQ3</accession>
    <name>A0A010YTQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710471.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.725"/>
    <dbReference type="HOGENOM" id="CLU_039929_3_0_0"/>
    <dbReference type="OrthoDB" id="1529037at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="297" mass="32620" checksum="F2189BD060C38716" modified="2014-06-11" version="1">MTSDMMVQHFFNALMLGSLYGLIAIGYTMVYGILRLINFAHGDIFMISTYFVFLAITVMHLPWIPAVLLSILATAVFGVMIDRVAYQPLRNAPRISALISAIGVSFFIENLCLVIFTGVPKPMPRFEPLVRVMTLGNVRILPLAIFVPIISFVLVGALLWMLYRTKPGLAMRAISRDIETTRLMGVKVDRIIALTFAIGSALAACAGIMWALRYPQIHPFMGIFPGLKAFIAAVLGGIGSVQGAMIGGLLLGFMEIMLVAFFPALSGYRDAFAFVLLILILFYKPTGLMGEKLEDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTV5</accession>
    <name>A0A010YTV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441972.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046973_1_0_0"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028348">
        <property type="entry name" value="FAD-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038984">
        <property type="entry name" value="FAD_binding_protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="6">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="462" mass="49771" checksum="ABD43F8FD2A3E202" modified="2014-06-11" version="1">MTKRYDAIIVGAGPAGLFAAMELTDKGKKVIVIEKGRSIENRKCPMKLGSPECVQCRPCNVVCGWGGAGAFSDGKLTLTPEFGGNLEEYCGREKLLSLISEADEIYLRHGASKTLFEPSGDLAKKVITRALQAGLDIIPATIRHMGTDRSKYILGAMYETMKGNCDVMTGTPVDRVLLKQDGSAAGVALESGEEIFADNVLLAPGREGAAWMERTVHALGLEIESLPVDIGVRVEIPAAWAEDITDQFYEIKAILDTPTFDDRVRTFCMCPHGEVTTEFQSHHDILTVNGHSNRENDKKTGNTNFAILVSTKFTKPFKDPIGYGSHIARLANMLGGGILVQRLGDLRKGRRSTHDRIARGLVTPTLASAEPGDLACVLPYRHLVGIMEMLSALDNIIPGINGTHTLLYGVEVKFYSLKVALDRGLQSSIKGLYAAGDGAGVTRGVIQASASGLWAARSILGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU13</accession>
    <name>A0A010YU13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethanolamine utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.833"/>
    <dbReference type="HOGENOM" id="CLU_082122_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010424">
        <property type="entry name" value="EutQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36169">
        <property type="entry name" value="PTHR36169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06249">
        <property type="entry name" value="EutQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="172" mass="18972" checksum="0D03294EEF20DBF8" modified="2014-06-11" version="1">MPALCEGGCAGCPIAKQEAKKMENTSGMNVSEKMLREIVTEVVQSMAARQPATGGFTKIVDPSGIILIKSETVKCEPFHGEAGVKLKDVVTLEEAPRIGAGIMELDRTSFEWTLTYDEYDVVFEGVLEIEIDGRVVTGKPGDIIYIPKGSHIHFRTPDKARYAYFVYPANWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU18</accession>
    <name>A0A010YU18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgB</name>
        <name evidence="12" type="ORF">Cloev_0786</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710692.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.838"/>
    <dbReference type="HOGENOM" id="CLU_004245_3_2_0"/>
    <dbReference type="OrthoDB" id="227746at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="158"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="638" mass="72036" checksum="F449AB61F2BA1C33" modified="2014-06-11" version="1">MQNEIIYGPTLAGEEDVYLFREGTHRRIYDFLGAHPLEHEGRPGVLFALWAPGAKDVYVMGDFNSWDREGCPLSPRWDSSGIWEGFVPDAAPGHRYKYLIRTAGGGMLEKSDPLAFGTELPPASASVVCDPAHEWLDAEWMAKRAGRNAVDAPQSIYEMHAGSWRRGDGDGILSWRDLAGELPPYLEANGFTHVEFMPVMEHPFYGSWGYQTTGYFAPTSRYGSPEDFMALVDALHARGIGVILDWVPSHFPTDSYGLSRFDGTALYEHEDPRQGFHPDWKSAIFNYGRNEVRSFLISSAHYWLDRYHADGLRVDAVASMLYLDYSRRGGEWIPNKYGGKENIEAIAFLREMNGALYADFPGISVTAEESTSWPMVTKPVWLGGLGFGYKWNMGWMNDFISYMSQDPVYRKYRHDQLTFGMWYAYSENFVLPFSHDEVVYGKCSLLEKMPGDGWQKAANLRLMFGWMFGHPGKKLVFMGGEFGQSREWNHDRSLDWHELGDPRHAGIARWFADVNNFYRSRPELWELDSSPDGFEWIDCSDRDAGVVSFIRRDREGRSVVFAANFTPVVRYGYRVGLPAGGRWDEALNSDAEIYGGSGVGNMGGVEAEEVPFHGQDFSAALTLPPLGIIILRAPALCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU69</accession>
    <name>A0A010YU69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster biosynthesis protein, NifU-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710778.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.884"/>
    <dbReference type="HOGENOM" id="CLU_079283_0_1_0"/>
    <dbReference type="OrthoDB" id="1793654at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="164" mass="17567" checksum="FB47491617FC1DF3" modified="2014-06-11" version="1">MYNQKVVDYFMNPRNAGKLDDANAIGEVGNPTCGDVMKIYLKIDPGTEVIEDIRFETFGCAAAIATSSMVTELAKGKTIAEALKINNKDVAEALGGLPPVKLHCSLLAQEGIQAAVADYYLRRDGKLPEGLSFPGNCTACGGACGGHEEEEEERFVGEDHRVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUG5</accession>
    <name>A0A010YUG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442168.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.984"/>
    <dbReference type="HOGENOM" id="CLU_001681_2_1_0"/>
    <dbReference type="OrthoDB" id="117507at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="19"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="775" mass="84062" checksum="F84D13C9008E2A2A" modified="2014-06-11" version="1">MYSVIGKSHPLIDAVDKVTGRQIFGSDYSVEGMLFGSVLRSPFPHAYIRGIDASNAKAVKGVRAVVTGKDIEMPYYSVAGVSKLDEQILAFDKVRYVGDEVAVVAADTLDAAQEAASRIKVDYEEMPAVFDTEEAMRADAPIIHERFGSNIANVMNVSHGDIEMALGEAALVVTGEFTSGRIHHGYLEPNAGVASWIGDKITFWLPTQSPVLARMTYAKALGVRRDQVKVVQLPLGGGFGGKLEYKLHPLCALLSKFSGRPVKMVNTRQEEMTASLPRVPIKLRMQLALSAEGKFLGKKVRLVCDNGAYMNYGIGIQLSATTRNDNLYRIENIKTESYLVYTNSMPTGAFRGFGCPQSHFAQETLIDEAAVKLGIDPAGLRLMNASQKDDITPHNWWFGSCGFSDCIKQSVEAAKWSEKKKEYQLTHNDKWSKGIGIASCLHVSGNRTFLPFFDGSSALVRINEEGRVTIFPGEVDMGQGCKTVFAMIAAEELGIPVDWVSVADMDTETCPHGMGTFGDRVTTLGGNAVKNAAIDARRILFESAAKHLHSQLDQLSVKEGVIYSSNGELINFAEASELASYEQAGATIIGHGSFQPPNVSMVDPITKVGNVSCAYPFVTQIVELAVNRETGEIKLLNVVSSHDLGRAINPMMAEGQVHGAVAMGLGFALYESMIEKNGTVANQSFKHGSMPRMTDMPPLISLLIESDDPNGPYGAKGLGEPALTSIAPAVANAIYDAVGVRIRSLPITPEKMLAAIQEKIDSERDDDRYEEINVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUK9</accession>
    <name>A0A010YUK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">Cloev_0978</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710983.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1048"/>
    <dbReference type="HOGENOM" id="CLU_122625_1_3_0"/>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="101" mass="11377" checksum="78070782D2D3BC5A" modified="2014-06-11" version="1">MAKKIRIKLKAFDHRVLDASATQIADTAQRTGARVSGPVPLPTEVNRYCVLTSPHVDKDARDQYEIRTHKRLIDIIDPTQKTMEALMELNLPSGVDIQIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUM1</accession>
    <name>A0A010YUM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ORF">Cloev_0993</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711007.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1062"/>
    <dbReference type="HOGENOM" id="CLU_098428_0_1_0"/>
    <dbReference type="OrthoDB" id="1692188at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="134" mass="15162" checksum="8EB2C94195372098" modified="2014-06-11" version="1">MHITDPVADMLTRIRNANVVYHEMVDMPLSKMRLEMARILKEEGYIRNYKTITDAKQPMPILRLTMNYGPQKERVIQGLRRISKPGRRIYVGKDELPKVMGGLGIALISTSAGLMTDASARKRGLGGEVVCYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUQ1</accession>
    <name>A0A010YUQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proline-specific peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_1034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442333.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_15_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01250">
        <property type="entry name" value="pro_imino_pep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="31"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="298" mass="33812" checksum="B7C10381D4E336E4" modified="2014-06-11" version="1">MAVSMKTEYIDVPGGYLCLNVYGAEKNSNIPVLYIHGGPGGNIESFRPMAERIAEDRTVYLYNQLGCDENSHTGEESLWVPERYIESLNSIIAAIGVPKLHLIGRSWGAYLAAEHAIRSHNSPVISITMISPLVSTKIWIADAKQRLAELGEDCLEAVEQCEREHHFDGRYYQEIIKKYDDNFRYRLSTVTRAGHAATPLKPKTASGLRVYRHMWGPSEFTCEGVLKDIDITGSLCKIRVAVLLICGEFDQVRQPTCEYYRSLIPGSRMAVIPDSSQTSYLEQPHIFYWTLRNFYECF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUR0</accession>
    <name>A0A010YUR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde:ferredoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_1044</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AOR/FOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1116"/>
    <dbReference type="HOGENOM" id="CLU_020364_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.569.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.599.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.9.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013984">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013985">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013983">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036503">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001203">
        <property type="entry name" value="OxRdtase_Ald_Fedxn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036021">
        <property type="entry name" value="Tungsten_al_ferr_oxy-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01314">
        <property type="entry name" value="AFOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02730">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00790">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48310">
        <property type="entry name" value="SSF48310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56228">
        <property type="entry name" value="SSF56228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFOR_N" evidence="8">
        <location>
            <begin position="23"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="728" mass="82364" checksum="4A0593A5178999BE" modified="2014-06-11" version="1">MANAPMKLLAEWSFEPAKIHHGYSKETLYIGLGNKDGNYKFEQRPVSEDMIEKFTGGRGFGLKLLWDAVNEKTKWDDPENEIVIAGGPFCGITQYPGAGKCYSVFLSPATRQTYNSNAGGYFAPFLKFSGFDAMELQGKADRPVVVFIDGDNNKVQIFESTLEDINAYAVSEDLHEYFAKDEKDKNTISVVSSGIGARTSYWAGMNFSFYDVRRKAVRLKQAGRGGGGTVLCDKNVVALVVKRTHFTGLENDPVDIKTIQRAGASLHKRIHDLDDKQCKMRSAGTAHLTEVMDDYTLLPVNNYKFGRHKDIDNISSNSYIKLFTQGMADGCWYGCSLACAKAVDHFPLQTGPWKGKEVIVDGPEYETAAGLGSNLGIFDPLWTIEANFYADHYGLDTISLGTGMAFVCECFELGLINKENTHGLDLNFGSKHDIMELLHRIAHGSDEFAVACGKGIEVAREYFAEHYGADMKKMMKIGMVCQGLEASEYRCQESIAQWGGYFLTLKGPQHDEAWLIFMDMVNKQLPTYEDKAEALFFFPNFRLWFSLQGLCKLPWNDIEPADNGMKYKGIEAARVPEHLQNYLDIFEAITGKHLTRDGLIEQSEKVYNFERIFNLRMGKGTSKYHEAPDRGLGPVWEDEWNARPEYFDGRLKEFSVDIEGLSVREKIDLLQKHRREQWQMLKMAVYKRRGWNKNGIPTLATVRRLGIDYPDVVALLEKHLKPEDEFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUW7</accession>
    <name>A0A010YUW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_1111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484913.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1184"/>
    <dbReference type="HOGENOM" id="CLU_027579_2_2_0"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="369" mass="41925" checksum="32E755EAF486C891" modified="2014-06-11" version="1">MSCRSLYIHVPFCERKCNYCAFESAVPREGERELWLSMLEREFSLRLSSAERPRLATCYVGGGTPTTLTGPQWLALTELIERYFDFDQKAEVTVEANPNSLRAEHLLTWRDWRVTRVSIGVQSFDDAELSLMGRLHSPRQAHGAISAALASGFSVSADFIFGLPYQSFANWGRTLREAARCGLDHISLYQLSLEEGTPWGSLDEKILGDGYAAYRWAQWYLPRKGYAQYEVANFAKPGRESRHNINYWREGEYFGAGPGAAGYLSGLRYKNFGELRRYAAELTKGRLPVEEEERLPLEKSAREAAVLGLRMTSGIDRTAFTERYGEKALDSLTASLRKFPRDLYENDGRGIRLTRKGLRVANLIWSEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUY3</accession>
    <name>A0A010YUY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enoyl-(Acyl-carrier-protein) reductase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711258.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1199"/>
    <dbReference type="HOGENOM" id="CLU_038732_1_1_0"/>
    <dbReference type="OrthoDB" id="275153at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017569">
        <property type="entry name" value="Enoyl_ACP_red-II_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03151">
        <property type="entry name" value="enACPred_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="5"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="315" mass="32971" checksum="80AC13968D31008F" modified="2014-06-11" version="1">MFENNPVTKLLKIKYPIIQGGMAWVADADLAAAVSNGGGLGIIAAANMPPELLERQIIKIRTLTDKPFGLNIMLMSPTADDALELAARHNVPVVTTGAGLPGKVLEKLKPLGTTVIPVVASVSHAERIAKQGADAVIAEGTEAGGHIGEITTMNLVPQIVDAVDIPVIAAGGIADGRGAAAAFVLGASGVQVGTRFVCAEECNVHINYKQKIVKANDRATAVTGRSLGHPVRAIKNKFIKQYEELEKRGAPAEELEALGAGKLRLAVVEGDTEMGSLMSGQSAGLVRAIEPAAVIIESIVSQMNNIFSEMTRYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGX2</accession>
    <name>A0A010ZGX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="3">6.3.5.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cobyrinic acid a,c-diamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cbiA</name>
        <name evidence="6" type="ORF">Cloev_0078</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine = 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:26289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="ChEBI" id="CHEBI:58894"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 10/10.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CobB/CbiA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.11" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441257.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.92"/>
    <dbReference type="HOGENOM" id="CLU_022752_2_0_0"/>
    <dbReference type="OrthoDB" id="692368at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="9"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="247"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <feature type="site" description="Increases nucleophilicity of active site Cys" evidence="3">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="456" mass="48952" checksum="8D36EF09EEE96345" modified="2014-06-11" version="1">MSRSERPRLLIAATQSGSGKTTITSGIIAALAARGLRVHPYKVGPDYIDPGYLGLAAGGRADNLDTWLTGEAAMKKIFLSASEEADISIIEGVMGLYDGGRGGVSSTARIAKALGAPVLLVIDVRSMGESAAAIAKGFRDYDPEVDIRGVIINRYGSENHRAMCAEAIERAGLPVLGAVPRNKEAEVKERHLGLLPVEENSNREHIENIRKMIEPAVDLEALLKIAASAPPIAPEAAAAPRSEKKVKIAVARDEAFSFYYPESVAVLEAAGAEIIGFSPLNDEKIPDCHGLIFGGGFPEIFAARLAANASMKESIARAAAADMPIYAECGGFMYLTREIKDFDGAAHRMCGVIPMSCKMNDSLRTVGYVTAKALSDNVVAKKGEELRGHEFHFSSAEPDGEIPRAFLFTKNRTGEKYPGGWADKNILGSYLHLHFAGFPKAAELFVEKCKEFRDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH32</accession>
    <name>A0A010ZH32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441322.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.148"/>
    <dbReference type="HOGENOM" id="CLU_833420_0_0_0"/>
    <dbReference type="OrthoDB" id="556139at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025964">
        <property type="entry name" value="GGGtGRT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14057">
        <property type="entry name" value="GGGtGRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="336" mass="35388" checksum="912D0A6AE1A64CC0" modified="2014-06-11" version="1">MANFEGYERRIDKINSFLAGIGFDCLEEAQQLCLDKGVDVAAIVRGIQPIAFDNAVWAYTLGAANAIKSGSRTAAGAAEKIGEGLQAFCVPGSVADQRKVGLGHGNLAAMLLREDTKCFCFLAGHESFAAAEGAIGIARTANKVRKEPLRVILNGLGKDAAYIISRINGFTFVETLYNQYTGELEVTMEKPFSDGDKAKVKCYGANDVNEGVAIMRHEGVDVSITGNSTNPTRFQHPVAGTYKKWAVENGKKYFSVASGGGTGRTLHPDNMAAGPASYGMTDTMGRMHSDAQFAGSSSVPAHVDMMGLIGMGNNPMVGASVAVAVAVEEAAKAGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHJ0</accession>
    <name>A0A010ZHJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RND family efflux transporter, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0271</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441441.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_1_0"/>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="5">
        <location>
            <begin position="84"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="389"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="421" mass="45522" checksum="F125F40391A6AA55" modified="2014-06-11" version="1">MQNSEEKRNIELNSKQKSGWIKIALVVVIAAAAVYGYRTWSGGKAVQQQTAQAAEPLVIVKPVEKADSSSQPSEYVGRVEAIQTVQVKPQISGEIAKVSFKEGSIVKAGQLLFQIDPAQYQATVALRKAELEKAEATLAEAEKYHKRVMAANDQAVSAADRDTAESSVLQGKAAVSQAKANLRLAEINFGYCRITAPITGKIGIANLTKGNYVTPSSGALATIVQMDPVRVSYTLPDRDYLDQLELFKKEGSVYKTKLILSNGSELDVPGQRDFEDNTVDQMTGTVMMRLRYTNDSGMLIPGEMVRVFTQPVKSRIVNVIPQTAVMADAEGDYVYVVEADNSVRDVRVKLGREMGTLREVVSGLKDGQNVVVAGLQNLRPGTKVRIDTSASANEATSNSVLDETSGAEIINSGDTGTKEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHJ7</accession>
    <name>A0A010ZHJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441450.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116722_3_1_0"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="45"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="115" mass="12093" checksum="D4A33219EA60EF3F" modified="2014-06-11" version="1">MSSVSLIKQDGEPRTVSNIRGGDGEARIFASPLPARGPLTLASRIELAPGASIGPHRHDSDEEVYAILSGEGVYIYDGGECPALPGDIFTTKKGMSHALKNRGGEPLVFFAVVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHK4</accession>
    <name>A0A010ZHK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3268017_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="41" mass="4638" checksum="D04614E3A576AA46" modified="2014-06-11" version="1">MTSLFSLSGGNTKQFNDRLGRCVCLPRRDGNFLLKDFFIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHR2</accession>
    <name>A0A010ZHR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709016.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.369"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_0"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="393" mass="43074" checksum="11F7B69D25324EB0" modified="2014-06-11" version="1">MKDFTASRVCALTPSGIRKVNERALAMERAGERVIHFEIGRPDFDTPAYIKEAAIKSLRDGEVFYTSNFGMMELRETIAERLAKANGIPCAAENILVTAGLSEAVFDLLCTILNEGDELLIPDPVWINYLNVPALFNARPVSYSLTEENGFEPDLAEIKSKITPRTKAIVLLTPCNPTGGVLSRGTLEGIAELAKAHDLLVVSDEIYERLVYDGKRQTSIASLPGMADRTVTFNGLSKAYSMTGWRLGYAAAPKDLIIAMNKIHQHNTTCAPSFVQRAAITALRDEGDEVELMVREFERRRDYAVEAINKMEGASCVTPKGAFYIFINVKGLGRPCAEVAEYLLEEAKVALVPGNVFGRNGEGYLRMSFANSLDNIAEGCGKMKQAFAELSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHY7</accession>
    <name>A0A010ZHY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709124.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.464"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="317"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="8"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="424" mass="44971" checksum="35646FDD9C24655E" modified="2014-06-11" version="1">MITGILLFGSFALFLVLGVPIAMALGVATLLTLKVIYPELSLGIVTQRMFAAMDSVSIMAIPFFVLAGNLMTKGGISRRLVDFSNQIVGNVRGGMAAALVIACAFFAALSGSAPATVVAIGAMLYPDMVKLGYPKTRTAGLLVVSGGLGPIIPPSIIMIVYGTITGASISQMFKAGMYIGLMIVAALLVLVFIYARKENWPKNMEKFSLAKLVKTFFGAIPALMLPIIILGGIYSGLFTATEAAAVAVIWALVVGMFIYRELSFKDLWPIFLSSGKSATMVLFIIATSTAFAWLFTFSGLAQLMISSITAMHLSPTLYCLIVAIILLIFGTFLEGVATAVLLVPVLWPIANSLGVNIIHFGMIVSISNVIGTMTPPVAVNIFSAASVTHLKMGDIVKGEIPFFVGYTGVFFLVVLVAKISTFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIP8</accession>
    <name>A0A010ZIP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ORF">Cloev_0697</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445245.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.743"/>
    <dbReference type="HOGENOM" id="CLU_003601_3_3_0"/>
    <dbReference type="OrthoDB" id="177859at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="67"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="557" mass="59516" checksum="D2A084FBE93018AE" modified="2014-06-11" version="1">MAFLSDIEIAQQAKMEPIAEVAKKLDIDADDLELYGKYKAKVSFDLWNKVKDNKDGKLILVTAITPTPAGEGKTTTSVGLAQALAKLGKKVTLALREPSLGPVFGVKGGAAGGGYSQVVPMEDINIHFTGDFHAITSANNLLSAMVDNSVQQGNPLNIDPRKIVFKRVLDMNDRALRNVVIGLGGKPDGVPRQDGFDITVASEVMAILCLSTGIEDLKERLGNIIAAYTYDDKPVTAKELEAQGAMAMLLKDAIKPNLVQTLEHVPAFIHGGPFANIAHGCNSIMATKYGLKLADYFVTEAGFAADLGAEKFLDIKCRLAGLKPNAVVIVATIRALKMHGGVAKEDLGKVNMAALEAGIPNLEKHVENMLSFGLPVVVALNAFPTDTEEELKFIQEKCAKLGVPVVESDIWAKGGEGGIEMAEAVIKACDKENSFHYLYDEKLSPKEKIETIATKIYGADGVVFTDKAEKDLKKIHELGKDGLLICMAKTQASISDDASKKGRPTGFKLTVREVRLSAGAGFIIPITGAIMTMPGLPKRPAACSIDVDAQGKVTGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ07</accession>
    <name>A0A010ZJ07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0787</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.839"/>
    <dbReference type="HOGENOM" id="CLU_014132_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="518" mass="57637" checksum="5CBD751809F178AC" modified="2014-06-11" version="1">MEKGRRSGVLLHISSLPGAFGVGDFGPEAFAFADYLHGAGFSVWQILPLSPAISIFGYSPYSSPSAFAGNMLFISPRRLCAEGLITEAELSSHMLPAASAADFDAAGRCRRDLLSLSWKRFNGDPEAFSGLRGPFEDFRGRESFWLRDYALFTLLKERYGDRCWPEWPREFASRDEGALAAFAAKNEEALSFIEFTQFIFYRQLEALSEYCAARGVTLMGDLPIYVAWDSADVWSHPGAFDLDAEGRPRCVAGVPPDYFSATGQRWGNPLYNWEAMRADGFAWWRGRLAHSLKYCGLMRIDHFRGLCAYWEIPASERTAQNGCWRPAPGREMLEAFCSDLGAGAGELPFIAEDLGVITDDVRALMEEFSLPGMKVLMFAFGDGVADNPYAPHNIRPRSAVYTGTHDNDTAVGWWRGSSTVRERVNFAAYAGREVTRENVSRVMIQMALSSVADLAVIPAQDLLGLDGSCRMNRPAAARGNWSWRLLPAEFCSLLPGGHDFSERLRELNILYGRFKEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ71</accession>
    <name>A0A010ZJ71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442070.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.895"/>
    <dbReference type="HOGENOM" id="CLU_083486_0_1_0"/>
    <dbReference type="OrthoDB" id="1401910at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="6"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="168" mass="18645" checksum="7E0C06905E3D4109" modified="2014-06-11" version="1">MARFNVITKGGDKGTTSLANGERIAKDDRVVELYGTIDECQAALGMARAFCEDEKTARDIYFIEDYLFGAMAYYAKCDYPAPDPAIIENMAARITEALPEGGMTFVRPGDTRCGSALHLARTIARRAERTATPLFRDGKLEEKAYQFLNRLSDVIYLLSLKVDADAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ83</accession>
    <name>A0A010ZJ83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase</fullName>
            <shortName evidence="6">TDH</shortName>
            <ecNumber evidence="6">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tdh</name>
        <name evidence="8" type="ORF">Cloev_0853</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442077.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.909"/>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_0"/>
    <dbReference type="OrthoDB" id="972769at2"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00627">
        <property type="entry name" value="Thr_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004627">
        <property type="entry name" value="L-Threonine_3-DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00692">
        <property type="entry name" value="tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="7">
        <location>
            <begin position="16"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="290"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom" evidence="6">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="347" mass="38436" checksum="EECDAB7AE8E0EBBB" modified="2014-06-11" version="1">MKGKMLALVKEKPGVGLWMREVDIPQPGPNDVLIKIKKTSICGTDLHIYNWDEWSQKTIKTPMTIGHEYVGEIVELGSHVRGWKVGERVSGEGHIVCGECRNCLAGRRHYCPHTIGVGVNRDGAFAQYLSIPTTNVWRCAPEIPDDIISCFDPLGNATHTALQFDLIGEDVLITGAGPIGMMAAAICRHVGARNVVVSDLNDYRLDLAKRLGATRTVRADREDLRDVMRELGMKEGFDVGLEMSGSPQAFSGMVNAMHNSGKIALLGLVKPGTVIDWDKVIFNGLTIKGIYGREMYETWYKMTTMLQSGLNISEVITHRFDVRDFEKGFEAMNSGQSGKVVLDWQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJC8</accession>
    <name>A0A010ZJC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylglycerophosphatase A-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103734_1_2_0"/>
    <dbReference type="OrthoDB" id="1969080at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06971">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026037">
        <property type="entry name" value="PgpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036681">
        <property type="entry name" value="PgpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007686">
        <property type="entry name" value="YutG/PgpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36305">
        <property type="entry name" value="PTHR36305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04608">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006162">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101307">
        <property type="entry name" value="SSF101307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PgpA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="162" mass="17417" checksum="925DF2E886A95181" modified="2014-06-11" version="1">MILTPEMKTWYGMIATVGTLGRYSKMPGTLGSIAGTVLWLLFGGIPIWAIAAVAAIGCYAADKYEKAAGREDPGEAVIDEVVGVWISSWGFELTYAVVALFLFRIVDITKPFPVKEFEKLPGGIGIMADDIAGGVIVNLLLHFIHWLIFAGGLSTILELIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJG7</accession>
    <name>A0A010ZJG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrothymine dehydrogenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dihydrouracil dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0913</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydropyrimidine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442158.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042042_4_3_0"/>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044512">
        <property type="entry name" value="DPYD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073">
        <property type="entry name" value="PTHR43073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="335"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="368"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="406" mass="44212" checksum="90DA3184E9E624D1" modified="2014-06-11" version="1">MKPNLTVEYCGVKFKNPMVIASASPSKNGEYMRRCAESGAGGVIAKTYSPEPLAQKYVSPRFTVLHKKGWPNNYSNYSCEFLATYNTEEWMNEMAIAKKECDERNCTLVGSISGNSKESWIELAKRMEDLGLPMLELNFGCPHPKDLGYKSGQELGNSPEAAAEVTRIVCDAVKIPVFVKLTSEAVSIVDVAGRCKEAGAAGFTVVNRFSALDVDIETGRPLLHGGYAGVGGPWMRPITLKWIAKIAAATGMPISATNGIFSWEDVIKCIMCGATTVQTCTAIMYGPKQFAEVGNFLAGVEKYLADHNIDDINKLRGITLPQIITWDKVDREHTAISKVCQDKCVGCGLCPSWCFYDAIKIVDVEGKKKSYIAPDKCDGCGLCAALCPKDAIKMEGEVPVYLGDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJK7</accession>
    <name>A0A010ZJK7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 6">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="8" type="ORF">Cloev_0974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 6">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710980.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1044"/>
    <dbReference type="HOGENOM" id="CLU_104295_1_2_0"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="123" mass="13820" checksum="CD5F7AF857BA58B3" modified="2014-06-11" version="1">MPTISQLIRNGREEKRRRSSAPALQENPQRRGVCTRVYTVTPKKPNSALRKVARVRLTNGIEVTAYIPGVGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDCGGVENRRQSRSLYGARRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJN8</accession>
    <name>A0A010ZJN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">Cloev_1014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711034.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1083"/>
    <dbReference type="HOGENOM" id="CLU_052037_0_0_0"/>
    <dbReference type="OrthoDB" id="410781at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="347" mass="36820" checksum="F3C0633082735840" modified="2014-06-11" version="1">MWNRDIGIDLGTATVLVFVKGKGVVLREPSVVAMDQSTGKILSVGEDAKIMIGKTPGNVVAIRPLRDGVIADYTMTEVMLREFLKKTTSGMERIVRHRLMIGVPAGATDVERRAVLEAALEVGAKEAYLIEEPMAAAIGANMPVGEAVGNMVVDIGGGTTDIAIVSLGGLVVFESLRVGGDKFDEAIVRYMRKQYNLAIGEQTAEDVKKQIGACDPTKASPDKIMDIRGRDLVQGLPRQVTVNSVDVAKAIDEPVSSIIAGIKRVLEKTPPELSADVMDRGIILTGGGAYLRGLAELIMEETEINAVVAESAGECVALGTGIALESLDKLKETGAVYLATKKGFKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJU4</accession>
    <name>A0A010ZJU4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cloev_1084</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484908.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1153"/>
    <dbReference type="HOGENOM" id="CLU_016755_0_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="344"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="181"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXG78929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="468" mass="49839" checksum="1DAC38EE6A7C85F1" modified="2014-06-11" version="1">MDSYDLIIIGAGPGGYVGAVRAAQLGLKVCVIERRDVGGTCLNRGCIPTKSLLYTSELFAKANHDFELLGLHADNVSCDPVKMYDRKDQVVGRLRSGVEQLLKANGVVRLFGCGSVAGPGSVKFTSPDGEETMLTAKNILIASGSKPSRTQFPGCDLPGVITSDELLADSGVVKKKLLVFGAGVIAVEFATVFANLGCEVAMVVRSRLMRVWDDDISKNFGTVLKKRGIKVYGKSVVKEVVRAGDGLLCRFASDGKDFELEADSILVANGREPDTEGLYCGGFTLPMKNGCIEVNDSFETSVPGIYAIGDVIGGMQLAHLASAQAISVCERLAGEEPSVCLEFIPNCIYTAPEIASVGLTEAEAAERGRKVIIGKYMMMGNGKTIIENGERGFIKLVFDADTDVLLGAQLMCERATDMIAELATACVSRLTAEQLTRVVRPHPTFCEAVTEAVEAAHGRSIHSAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKX1</accession>
    <name>A0A010ZKX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaA</name>
        <name evidence="14" type="ORF">Cloev_0001</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441191.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.2"/>
    <dbReference type="HOGENOM" id="CLU_026910_3_1_0"/>
    <dbReference type="OrthoDB" id="219876at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="141"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="354"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="149"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG77907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="444" mass="50456" checksum="72076189E5681F09" modified="2014-06-11" version="1">MDLDIIWKEYYKYCMEKLGTEDKTAEIYLQTCMPLSLDDGVLTLDVATQFAMDQINSRYLARMRELLIETSFGTDVRLRVSSDQPEDTRVQEPQPKAQPPKPASGRNGLNPNYVFSTFVVGKSNRLPHAASLAVAESPGNTYNPFFIWGKVGLGKTHLMHAIGHHIEATNNNTKILYVSAEKFTNDLITAIRNNTNQEFRARYRELDVLMIDDVQFIAGKEQTQEEFFWTFNTLHDAKKQIIISADRPPKDIEGIADRLVSRFEWGLVTDIQPPDLETRVAILQKKAEMKKYMNIPEDVIMFIAQNIPSNIRELEGSLNRIVACSDLNHEPINIENASVWLKDLIKEHPVGTVSIGLIQQMTAEAFGFSVEELLSKKRTADLALARQAAMYVARNKTNEALIQIAYAFNKKDHTVVIHACRKIAELIKTDLRIRSFVDNIVNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL60</accession>
    <name>A0A010ZL60_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ORF">Cloev_0101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441296.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.115"/>
    <dbReference type="HOGENOM" id="CLU_054212_0_0_0"/>
    <dbReference type="OrthoDB" id="2029688at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00380">
        <property type="entry name" value="cobD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="313" mass="34171" checksum="243CEE8BEC4271E6" modified="2014-06-11" version="1">MQILAALLLDALFGDPKWPTHPVVLVGRLITFYEKIFYSPSDGKRRGVIFCAAVLFTVAAAVAAGMIVTGLIGKWAQTAFLIYLLYAAIAFKSLKDESLPVARALAAGDLERARRQVGRIVGRDTERLDAAGVTRAAVETIAESYIDGVVSVLFWMTVGSFFGHAAIFAWLFKAASTMDSMVGYDDERYRDFGWAAAKLDDLLNFIPARLGALIAVGAGALANMDYRRAWRVFLRDRLNHKSPNSAHGESVFAGLLGIRLGGGAFYGGEWEARPTLGDDLREPEPNDILRAHYIMDVSAALCAVLIFATERFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL73</accession>
    <name>A0A010ZL73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709197.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1822026_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458201" evidence="1">
        <location>
            <begin position="26"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="141" mass="15663" checksum="B3955C1A40E77067" modified="2014-06-11" version="1">MKKILFAALALTMLATVCLSQAAFAENFVEVDRTERNIAYLDTDSIKDNGGYLTAVTKIILRTPEERAKFKERSGLDAHYVLMTFAYNKAAREDQLLKAEVVYGYETAGNESNEFSAQGWRAVPENTIGAVIYDKIIGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL89</accession>
    <name>A0A010ZL89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441327.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059362_1_0_0"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458344" evidence="1">
        <location>
            <begin position="22"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="50"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="205" mass="22065" checksum="AC0DE8B099EED94D" modified="2014-06-11" version="1">MKKILSLTAALLLAAASAATAANIVLPEPDKTGGPSVMEAIPTRASAEQRDFSKEELSLKELSTILWAATGKNREPKGWTVPMAMGREPYVSVYVLLKSGGYLYNWEKNALMQQTAEKKLTSRAVTQDFAKSAPCILVFVSKGTMNVENYNYIATGAMSQNVFLAAEALGLKGRFLASFNKVNIEAALTLGPIMKITGVMAVGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLA4</accession>
    <name>A0A010ZLA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:flavin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484775.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_1_2_0"/>
    <dbReference type="OrthoDB" id="671513at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="4">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_FMN" evidence="4">
        <location>
            <begin position="114"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Fer4_20" evidence="6">
        <location>
            <begin position="346"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="444"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="824" mass="90897" checksum="A0B20D9100B7B6A1" modified="2014-06-11" version="1">MQRIGLFTPIKINSMELSNRVIMSPMFTNSAAPGGFVSKNTIKHYVDRARSGVGLIMTEHTSVSSHFIHAGLRLQISRDEHIDGFKKLIAAVHDEGCKIGLQIAHSIYGVGRKPHELTNEECYGIIDDFAAGARRAYEAGFDAIELHYAHTYTMADFISRRTNLRTDEFGGDIYGRMFMHLEILKKVRAIVGPDYPLFARISAEEFVLGGNTIVQSRIFAQELVKHGIDCMDVSAGVRFDDAPVKGYSDQRGKPTIEYPDGPNVYLAEEIKKCVDVPVVTVGKLGNPEFADNVIAEGRADMVALARPLIADPMWVRKAKDHRFDRITECLYCTECLYERHDPSAYIHCMRYTCQNACPANVEVPVYLDFARRGMYKEAYQVIQNENPLVLTCGRVCNHLCENMCNRVKIDEPIAIRGIKRFITDWLLEHDGKFPLPPMEPENGKRVAVVGSGPSGLSCAFYLRKKGYEVTVFEALDVVGGMLAVGLPEYRLPADKFAKELELFREMGIEFVTGTKIGEDISIKELRKQGYMAVYIAVGDHNDRKLGVEGEDSEGVTSGVSFLRSVKTGGGCDLRGKEVIVIGGGNVSMDCARTAIRLGAAKVSLFCLEKEDEMPAHPDEVREGKDEGLYVFNGWGPMAISAKEGRADGVTFKKCTAVFDASGRFNPSYDESAQMKVHADFVICAIGQALSREVAAGDEELVDIRGNVIKAAYRGTTATPWIFAGGDCATGPDSVVGGVNRGKEAASSIDRYLGGDGQVIAHKYIKREMSKPIDENPTPREKMPALSPEERKSCFCEVEKGFCEGQIAKEAGRCLRCDVLKVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLE9</accession>
    <name>A0A010ZLE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709308.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149135_0_0_0"/>
    <dbReference type="OrthoDB" id="1648191at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="144" mass="16175" checksum="5F24960F9C1A2DF9" modified="2014-06-11" version="1">MAAPMQISLEEIISMLLQRVESLSASDENSKTKQNIINRVLYKKGILTDEDILDSVKEEYRMLKELGVIQSEPDDAMYKTITDGVLQWIKGDVDGIKQSMADYEKKLQEYAREEASKKPKIEVAGANVLNQLDAAANKKGKLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLG4</accession>
    <name>A0A010ZLG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type metal ion transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709340.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.231"/>
    <dbReference type="HOGENOM" id="CLU_077375_0_1_0"/>
    <dbReference type="OrthoDB" id="1464674at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="9"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="211" mass="22247" checksum="3CCCF045FA568336" modified="2014-06-11" version="1">MGSELAAALWETLYMVAVSTLFSGIFGSGVAILMIITGPNGLKPNKAVYGVLDVAVNLLRSFPFIILLIAIIPLTRLIAGTSIGSTASIVPLTIAATPFVARLMEGSLLEVDRGVVEAARSFGASTAQIIFGVMIKEAMPAIVLNWAIVAINLLGYSAMAGVVGGGGLGDLAIKYGYNRFQTDVMVYSVAILIVIVQVIQYAGNYIYEKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLI7</accession>
    <name>A0A010ZLI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP-type C4-dicarboxylate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709391.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_1_2_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457982" evidence="2">
        <location>
            <begin position="24"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="333" mass="37572" checksum="F080E9CFCEB94F65" modified="2014-06-11" version="1">MKSFKNSLCVLMLLLFLAPCSDAAEVKLRFAGQFPEDHSAIKSMREIANGVREKTGGRVEIEVFPANRLGDYTIIYEDLMRGAVDMALISVPSQFDPRLELVYLNAFANYDVLKREFKPGSWLSKKMNEYNTRLGVKFLGFNIEGLTGIASKKPVREPLNPNINKGVLARVPFMNVYKSAAEAQGYRTISLPYSDIARSLQDGTCDAVSSISTGAALSELKGIMKYWYQLNYSQETESYLMSAKSWDKLSEDDLAAIYAEVAKASAKSFEQAQQNDRKNLEMMRKNGVQVFTYTDAELLPLRRAVMENWKQLDPTMGAQLMKEARKHFSIKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLJ4</accession>
    <name>A0A010ZLJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.258"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="407"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="491" mass="54142" checksum="D5DF8BF0290B5F75" modified="2014-06-11" version="1">MSSRLDIIIRDNLNRLPTEPFIWWQKTWWSRGAFLELIEECEERLRASNFKRGQRLALLMPNSPVLLATAVAVWRLGGAVVLIDFRSGYLPLIRQLRHADVFAALTYRGCEDLVQLISEEGIPCSVISLDTLEENIPGRPCAEESEETAVIFYTSGTTGEPKAVPLTHDNLLYCIEGCVEHIDMLNEDDVFLNALPNSNVFGFLCGALLPLVKATRQAILTSFMPVESSMDAIKHAEVTIATAVPTMIALMIGAVSRGATLSSSMRCILSGGDRLPARISARAERLLGVPVLQGYGLTEASSVVALPPSINAAKPGSVGTLLSCVEAEIRSDEGAVLPQGREGHLWIRGSSVAKCYYRNPELTAERFENGWFNTCDIAKFDDEGYLYLVGRACDVIFVGGFKVYAREVEKTLEEHPLVLEAAVIGVPRSISGEIVKAFVVLKKGERVSAKELIEYCKKKLSYYKVPRIIEFVTEMPRSAIGEIVKRKLSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLM0</accession>
    <name>A0A010ZLM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Histidine biosynthesis bifunctional protein HisIE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <shortName evidence="15">PRA-CH</shortName>
                <ecNumber evidence="15">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Phosphoribosyl-ATP pyrophosphatase</fullName>
                <shortName evidence="15">PRA-PH</shortName>
                <ecNumber evidence="15">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">hisI</name>
        <name evidence="15" type="synonym">hisIE</name>
        <name evidence="17" type="ORF">Cloev_0258</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 15">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 15">In the C-terminal section; belongs to the PRA-PH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 15">In the N-terminal section; belongs to the PRA-CH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="15"/>
    <dbReference type="EC" id="3.6.1.31" evidence="15"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A010ZLM0"/>
    <dbReference type="PATRIC" id="fig|866499.3.peg.279"/>
    <dbReference type="HOGENOM" id="CLU_048577_3_1_0"/>
    <dbReference type="OrthoDB" id="1842189at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01019">
        <property type="entry name" value="HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023019">
        <property type="entry name" value="His_synth_HisIE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 15" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 15 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRA-CH" evidence="16">
        <location>
            <begin position="31"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-AMP cyclohydrolase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-ATP pyrophosphohydrolase" evidence="15">
        <location>
            <begin position="119"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXG78152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="211" mass="23380" checksum="2870C513B55F995E" modified="2014-06-11" version="1">MMNIDLSLIKFDEKGLVPVVVQDAVTAEVLMTAWANAEALAETARCEEMVFWSRSRGELWHKGETSGSRMCLRELRVDCDGDTLLAIVEPLGPACHTGERSCFYRSLCGEADSTEATFLGRLWRYLNVRKDDDPKESYTARLLRSGLSRVAQKVGEEGVETALACATGDRDGFRYEAADLLYHLLTACIAAGVPFDEVLRELASRHKGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLU4</accession>
    <name>A0A010ZLU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt ABC transporter, permease protein CbiQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0322</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708992.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.352"/>
    <dbReference type="HOGENOM" id="CLU_056469_1_2_0"/>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012809">
        <property type="entry name" value="ECF_CbiQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02454">
        <property type="entry name" value="ECF_T_CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="270" mass="29244" checksum="326FA485609ACCD0" modified="2014-06-11" version="1">MADLRGSIYEIYSLEQLAGGGSAIHSLDPRVKIAGTLFYIAAVISFGRGELSGLAPFVFYPAVALSLADIPFGMIFRRSLAALPFCLFAGISSLFFERTVLFTVCGFGVTTGWVTLFAIVFRTLLCVSAVLILVAVTPFRKLTGGLRSLRLPGILISLFEMTYRYLGTLAGEALSMYTAYSLRGGGKKGVEMRDMGSFAGQLLLRSFDRAERVYQAMKCRGYGGAPPAAANGGRLTPNDLIFLVILCGSSLLFRLINFPRLIGRLIECLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM46</accession>
    <name>A0A010ZM46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709116.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.457"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_4_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="88"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="379" mass="43079" checksum="4540D9F5AF0B4517" modified="2014-06-11" version="1">MRIKAFKLERLFARYAEQAKYMLSQSSCESCSMKEILDMADPECKKLWENLSLGYTRPAGFAPLREAISQRYTSIRPSDILELTPEEGIFIFMNNMLEPGDEVIVMHPTLPSLYELPRTLGCKVIKWPLEVTSWGWRLDVNFLAENISPKTKLLIMNVPNNPTGYIPVRTEMDRILNLADRMGTWVFNEETYRGMEHDPAAALPSLADIYPRATVIGGLNKYGLPGTRMGWLVSKNRQIIEECAGYKDYTTYCNNAPGEILATIAMRNALDLLQRNHKIVLENLGIAEAFFKKHRDLFQWIQPNGGSTAFPRLLPPYDVTEMCERAMTEKKLLIIGERAFGLDTNHFRVGLGRLDFSKALAVFAEIADEIQVNRAETAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM71</accession>
    <name>A0A010ZM71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2631902_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="77" mass="8828" checksum="3D5CE3C3D19F7A41" modified="2014-06-11" version="1">MGRHYVYRGKEVAACQVDFRDSSAFCTFWKASDGSARRLRHPELPEQASRSAAQGDLDRFAELRKLKVLERSARLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM78</accession>
    <name>A0A010ZM78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0464</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441693.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.504"/>
    <dbReference type="HOGENOM" id="CLU_024927_2_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="339" mass="37752" checksum="C1F9FD00C718B8C9" modified="2014-06-11" version="1">MVYTGDAFEILSTMPGGSVNCIVTSPPYYALRDYGVEGQIGLEATPEEYISRLVSVFDEARRVLRGDGTLWLNLGDSYSGSGKGAATDPLNASLYKQGTNMGLLGSQILRTCGKPKNLLGIPWRVALALQERGWILRQDIIWNKPNPMPESVVDRCTKSHEYIFLFSKQQRYFFDAAAMKEPRVSDENANGFRGGSYIHDSPSKRKTVGNIRYGGQKYTENPDVFFRTKSGNLYDENYLLRNRRSVWTVATVPFKGAHFATFPPELIRPCVLAGCPVNGTVLDPFFGSGTVGVVCREENRYYVGIEINPEYVRIARRRIAATEGKGKLRMDVDGGAIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMD4</accession>
    <name>A0A010ZMD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709636.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.563"/>
    <dbReference type="HOGENOM" id="CLU_082080_0_2_0"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="149"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="201" mass="21876" checksum="750F5761DB665FCE" modified="2014-06-11" version="1">MQMILASTNRGKYREMKAQLEPLGIELLFGGDFEKPLDVDETGESYAENALLKARAWAEATGLPALADDSGLEAEALGGRPGIHSARAVEGSDSDRMYWLLGEMKDKSDRRGRFACAIAVVFPDKKEPLTVTKYCPGQITREPAGESGFGYDPIFVPDGFDKTFAELGGEIKNKISHRAMAVKGIAEMLIPVVQSYAVRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZME9</accession>
    <name>A0A010ZME9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709655.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_6_3_0"/>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="37"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="331" mass="36213" checksum="293AB6A2AF02F6B9" modified="2014-06-11" version="1">MKVSEFFTGKRILIAILVILIVGSSVAIYFKEKPKDKYVRASGTVEVTQVQLAPLAGGRIVELAVEESDHVRKGQFIARLSMDGADDELKMAEAALAGAKAQLDELKNGFRKEDISKAKAELAARRVQYEQARRDEKRFAALAADGVVAERDAELYSEAAKASRSAMQAASDQVRLLENGMRPEQIAAAEANVARAESAYRKAKTLVGYKEFYSPADGVVLTKNYQVGDVVNAGAPIATLGDMNDCWVKLYIPSTQLGLIKLGAKCSVYVDPFPKRAFEATVTEVNQQAEYNPRMSLTQNERANMVFWIKISINDTEGVIKPGMPADVTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMG5</accession>
    <name>A0A010ZMG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709691.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_0_0"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="253" mass="28655" checksum="BC8B66CA7D9AA7E7" modified="2014-06-11" version="1">MNDKRRQVIEKLLEKINSGEVVSQDKLLPERRLAEVVGETRPVVREGLIALEAMGVLDIRDRQGIYLSSTEENEAKMMLHKVRGWPADMLSRVMEVRQIVEPPATAIAAVRRDEKDLTKMRECLRNLRELVEEGGEEAAQQSLIWNTAFHTVIVESAENAYLSRLYEGIHAVAEHSLSLMRIRTSPEKEGGRRSVYQDHLKLFERIEARDSAGAELCAEEHLRHSINAMVELGQIVPASDLFGQKLIGQARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN49</accession>
    <name>A0A010ZN49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710702.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023978_1_1_0"/>
    <dbReference type="OrthoDB" id="724641at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="437" mass="50779" checksum="60CB7FFB8B213873" modified="2014-06-11" version="1">MDKTELFYWLIWWGWWLVQFVLYILLGALMCDGVYQIIVSLRGFWSQKKMPQAKRYRRFAVLVPAHNEAMVIVPLLKSLAGQNYPKNCYKVYASCDNCTDNTAELARENGAVALERFDDEHNGKTWNVRWALTKIPFEEYDALAMFDADNLAEHNFLMAMNNYMELHPEAEAIQGVLDVKNPDDNWLTRSYALAYWFTNRFWQLARGLWGLSCTLGGTGLVIRTATLERIGWNLQSLTEDLEMSTRLILSGSRVHWNDAAVIYDEKPQDMAVSKRQRTRWMQGHYWVFWTYGWDSLKAFFVTRRLQYLDLFLYLLAPAKSCLGIIIMIAGMAFTLVNNMVLYPSSDIPQSMLEWTLFFGLPIFSIIAFCLLCAIAGPSMHEKKFTLRYVKDTFAYFWFGLTWIPILFKAAFLAKDQGKWVKTEHTRGISLDDVKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNF1</accession>
    <name>A0A010ZNF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-asparaginase/GlutRNAGln amidotransferase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019134_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Asparaginase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="2">
        <location>
            <begin position="216"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="331" mass="35978" checksum="E550505C9E9BBAE3" modified="2014-06-11" version="1">MLPLPKLALVIAGNFSADEESADPGILLGYLPEDLARCCEIKEWSCQPSTHYSMPMTLAMEEMFESLIAEGYTGIITVCGSGVMEEMAYLVNLLWQHSEPVIFANLMVQGRAGLKEGLVNLHCSVLAAISPMARDKGVLLCSSGELFGADDVTLVDPGSPDSAFQSQERGSVGKMLNGEIKFFSEPRRPSFLARRPKELPCVEIMWASLGGGDGLLSFLAAHRELGGLVLAGFGAGNVPPLWVPPIRNILRRRIPVVITSRCFQCHVHKTNDFEGSFEKLTEMGVMSGGRLNPFKARIRLSLGISAGLTDNGLSLYMLNQPVSDDINTLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNI8</accession>
    <name>A0A010ZNI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.976"/>
    <dbReference type="HOGENOM" id="CLU_074521_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021269">
        <property type="entry name" value="DUF2848"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11010">
        <property type="entry name" value="DUF2848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="233" mass="26562" checksum="C40C33B2B3A07FB9" modified="2014-06-11" version="1">MKFKVLEKNGEERVIDFIPKHIINAGYTGRDQAAVQAHIDELKEEGIPAPDKTPVYFPKFTDKLTQSEEFEVLDETDHSGEAEFALFFDKSEIYVGVGSDHTDRKLETIDIPKAKQIYPNTISKELWKLSDVIDHWDDIIIRSWIKADGEKKLFQEAKLTAMLDAADLAERAKKLLCDPKDTEGLVVYSGTVASLFKADYSPYFETELEDPILGRRLGNVYEMTCKSSWYKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNK7</accession>
    <name>A0A010ZNK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lauroyl/myristoyl acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0952</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442237.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049421_4_2_0"/>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="300" mass="32462" checksum="DB82853404DB3361" modified="2014-06-11" version="1">MAQSQPLIWHSLNTFRKLVCALPHERAVALGGALGSLVGRFSHKKVSEAQERCAKILGVSRERALEIVLGSYGHFGRAAAEFARMPVMADKIDSLMHSSGQEHLFEAVKSGRGAILATAHIGNWEYAACWLAHLGLPINSLGADQRDERITELIKELRRAGGSKALGKASDLKSMMKALQNGEIVAVPVDQDAKELGVVSPFLGFAASTPVGPAKLAAKLGCDVIPGACVRRPDGISFELTLLPPMKGRGGEPFGKDMQASTDDLNAVISEMIRAHPDQWMWMYPRWESVERGIFGDRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNL7</accession>
    <name>A0A010ZNL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442256.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1032"/>
    <dbReference type="HOGENOM" id="CLU_762739_0_0_0"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="2">
        <location>
            <begin position="100"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="417" mass="44923" checksum="3C3C89E519E0258B" modified="2014-06-11" version="1">MEHIKENEVKIYSISANSAAALAARNAELSRRLAAGDDLCGLFDTEKFTNDSHRMAFAASGRTGVIESLKTFRAAAVKGQKLIFAMPGQGSSGPVPLEYLCASMPTFREYIERAQERLTGGGAPSVKEILSRGKARGSMEEQLFIFIYGTAMAMQYCEWGAKPDIVIAHSLGELAAMVVCGMASYEEMLGFVQRRAQIIDALAGAGAMVHVAADIRDTCRVAASYGGKLSVAAVNSRGSAVISGEIKALTAFERELDRLSLPHKRLRVPKAAHSAMMEPALAPIAALDFPSVRDGVYPLYSSVTGAMLSAREAETPAWRVRHCRGTARFDLALAALSAGLGGNEAVAVEFGVHRVLAAAAIKAMPRVKWYGASTMARYHDGRSPEYCFKRGILETLAALWECGRLPRVQSFPHAIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNQ0</accession>
    <name>A0A010ZNQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsZ</name>
        <name evidence="5" type="synonym">rpsN</name>
        <name evidence="6" type="ORF">Cloev_0992</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711004.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139869_3_0_0"/>
    <dbReference type="OrthoDB" id="2032609at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_B">
        <property type="entry name" value="Ribosomal_S14_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023053">
        <property type="entry name" value="Ribosomal_S14_Z"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="61" mass="7238" checksum="03338EB4D4527408" modified="2014-06-11" version="1">MARKSMVNKAKQEPKFKVRKYNRCPICGRPHGYMRKFDMCRCCFRKLAREGKIPGVVKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZP02</accession>
    <name>A0A010ZP02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">Cloev_1120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442429.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1193"/>
    <dbReference type="HOGENOM" id="CLU_020352_0_1_0"/>
    <dbReference type="OrthoDB" id="537106at2"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="208"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="285"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="333"/>
            <end position="337"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="402" mass="43394" checksum="0E92FA3ACE2B159D" modified="2014-06-11" version="1">MKILVLNCGSSSLKYQLIEMDGEKVLAKGLVERIGIEGSRIKHTKTGMDSVTREVPFPNHSAAIKYVLDILVDPELGVLKNLDELYATGHRIVHGGEKFTKSVLVTPEVVKGIEEVIPLAPLHNPANLQGLKAVMEALPGKPNVVVFDTAFHQTMPPKAFIYGTPYDCYEKDRVRRYGFHGTSHGYVAGRAAEILGKDIKDLKIITCHLGNGSSITAVDGGKSVDTSMGYGTAEGVLMGTRSGNVDVSVMIYLMERYGDVQKVSDIVHKQSGLLGVSGVSGVSSDLRDVEEAAANGNQRAKIAQDILITGVKKYIGSYAAEMGGVDVVVFTAGIGENGIGFRKEVCENMEFMGIKIDPEKNNCRGKEVIFSTPDSKVTVMVVPTDEEMAIARDTKRCAEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZP24</accession>
    <name>A0A010ZP24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442454.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1216"/>
    <dbReference type="HOGENOM" id="CLU_169492_1_0_0"/>
    <dbReference type="OrthoDB" id="2036672at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="89" mass="10272" checksum="4A0969B7E2224DEC" modified="2014-06-11" version="1">MVGYSIVYTKKAAADIPNLKASGLEFKARALIDIIRINPFQSPPPYEKLVGGMRGAYSRRINIKHRLVYEVNEENRTVKIISMWSHYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A798</accession>
    <name>A0A011A798_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate ABC transporter ATP-binding protein, PhoT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034444907.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.25"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="252" mass="28103" checksum="7969100D3BD049C6" modified="2014-06-11" version="1">MENCAEIRGLRVSFNGETVLHGITADIPRHGVTVLLGRSGSGKTTLLRALNRLNESFAGYEGEGEVRLAIMGGMRPIYGSGAPDLTRIRRSVGMVFQSPNPLPLSFRKNMTLPLELTLNLKKDEAELRMEKSLRDVGLWDEVKDRLNRHAASFSGGQQQRMCLARTLALEPDILLLDEPTASLDRKSAELIEEHLDRLKDRIPVIMVSHSLAQARKLGARFKILSDGRIINELERDELPRGEAAEAFLEELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7B3</accession>
    <name>A0A011A7B3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708557.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.44"/>
    <dbReference type="HOGENOM" id="CLU_000445_52_2_0"/>
    <dbReference type="OrthoDB" id="1327994at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="76"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="160" mass="17335" checksum="5D4450DD6B54D26D" modified="2014-06-11" version="1">MKCYAKYYFDGVGTLTLGEDDGKLTDLHFASSGTHPGGDLMMSETPLLAEACRQLGEYFTGERKSFELPLAPKGTPFQLRCWEALLRIPYGATTTYGDIARAVGSPKGFRAVGLANNRNPIAIIIPCHRVIGSDGKLVGFGGGLDVKSFLLMHEAQHLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7E8</accession>
    <name>A0A011A7E8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709832.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.89"/>
    <dbReference type="HOGENOM" id="CLU_016047_14_3_0"/>
    <dbReference type="OrthoDB" id="1915735at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="6"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG77976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="236" mass="26226" checksum="6533333AA8E4B3B2" modified="2014-06-11" version="1">MDWFPLYNSLRIAGISTFLTFFTGICAAYYISKTSKLTKGVLDCLLTLPMVLPPTVVGFFLLKTIGPLGPIGSVVLELFGFRLTMTWYSAIFATAIVTFPLMYRTVRGAFDGFDHNLTYSAQTLGLSNTYIFWHIMVPNCKDGILAATVLAFARALGEYGATTMVTGYIPGRTATISTTVYQLWREGNDAAAYKWVMVNLAISFIVLVAVNMLENSYRQPKGRAVNHTLSEEFERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7F3</accession>
    <name>A0A011A7F3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP:corrinoid adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441261.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.94"/>
    <dbReference type="HOGENOM" id="CLU_088595_2_0_0"/>
    <dbReference type="OrthoDB" id="1690483at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="168" mass="18065" checksum="6CDA48BD18474CEC" modified="2014-06-11" version="1">MFDGEERGKVQIYTGCGKGKSTAAFGLAMRAAGCGGRVFIIQFQKGLRCGEHESAEKLGIELAQCPKGRGSGPCASPCPLLAAARGILERGDADLLILDEIMAAMRYGCVTREEALSLLDARGEKTELVLTGRGAPAELIERADLVTEMKKIKHYYDDGLPARRGIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7M2</accession>
    <name>A0A011A7M2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484777.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045683_1_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005064">
        <property type="entry name" value="BUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042100">
        <property type="entry name" value="Bug_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42928">
        <property type="entry name" value="PTHR42928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03401">
        <property type="entry name" value="TctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="328" mass="36288" checksum="5D25CC1F0E32D99A" modified="2014-06-11" version="1">MKKLVVLSILVLSLLINVFAVPSRLSAAEWPQSKVTLLIPFKAGGSSDSMGRGLAKYWEKYLGVPIVIDNRDGASSQVGTTIYSRLPADGNTIYLGCQVYFSSNIITHNAKYKFDQFDVLNIQQEDAIEIVVLNNSQYKDAKSLFKAIKEKPGTLKCGYIAGGPQNIAASILRKEHGLDFKSVTYDNGNALRTALLGEHLDFMIGNSSGDISVAGKAKVLVILGVKRSGLFPGAPTFSEVFEGKQFPALSMSTFVAVHSDLKKKYPERYKKLLDTYQQALKDPDYKKFLVDSKQDPINQYIGPEKSKTVNKAIHELVEKYKDELVVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7N4</accession>
    <name>A0A011A7N4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uracil-xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441361.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.192"/>
    <dbReference type="HOGENOM" id="CLU_017959_8_0_0"/>
    <dbReference type="OrthoDB" id="1419334at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="439" mass="45398" checksum="5F858F52F65B8420" modified="2014-06-11" version="1">MSQSTRKILFELRGIPKFTEALPLAMQHVVAMIIGCITPAIVISVVANVSPEDTMLLIQASLVTAAIATFIQLYPVAGRVGAGIPVVMGVSFAYVPVLIAIGGSMGPPAILGAQIVGGFAAIIVGIFIRRLRPLFPPLVSGTVVFTIGLSLYPVAIRYMAGGAGMPGFGSALNWGVALFTLAAVSFFSFFTKGFTKLASVLLGMAAGYILAASLGMVSFERIIESQWFQLPQVNHFKIEFHVTAVVSMVIMYIVNSIQAIGDISATTAGAMDREPSDNELAGGIMGNGLSSMLSAFIGGLPTATFSQNVGIVTITKVINKFVIALAAAIILLAGLIPKFAALLTTIPLAVLGGATLTVFAAITMTGMKLLLSAKLTPRNSAVVGISVALGVGISQVANALGGPGMPSWAQEIFGSSSVIISTLAAVALNVIMPRDKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7W4</accession>
    <name>A0A011A7W4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0242</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709403.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="212" mass="23020" checksum="E4C79D6F961A23C8" modified="2014-06-11" version="1">MSISIVLADDHPLTREGIKGYLSKEPDFDIVGEYADGNSTWTGIQTHRPQVALLDIRMPGLDGIALARKVKEAGIPTASLMLTSYDANQYVMAALRAGARGYVLKTATMDTLSRAIRIAARGGFYLDSDVASAVEEGEDFVPEPVSVREREVLLLAARGLSGKEIASQLFISERTVQTHLASIYDKLGAKNKTEAMLLSLKYGIATMEELLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7Z4</accession>
    <name>A0A011A7Z4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441438.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_259416_0_0_0"/>
    <dbReference type="OrthoDB" id="1089791at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459437" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1326" mass="143310" checksum="0F96A39816B1C49C" modified="2014-06-11" version="1">MKIPSIKKLLAVCCLLASALASAVYVRAEDSTYYTDPLAGIYEHASVSPKQRLIVSYLNKDGSMRSYEVSGKNATDPGTAPERVTKLTDFGSLTQSDTCHVFSSAAAQGNILSTVHLQEPFAGATEIPSVPQGVQVNTYFVMENRNSKRTTTSAWIEMTNGDGRIGRMKITEFTPAYTVAWRGDTIRRHDPLIGSNINHDLIAYDWNGDGYSDYLLTFITATDNDGQNAKVRLAVIDGKGLYEYLTGSSQTRPSVRFLNGEKDTPFLTGDKKNLVGGGSFRKPPHSCRTAIGDFDGDGRAEIAVYFTKIRGGNITEALDNHLVVYKLDKNFSATKIYEIDGKPCGRWFLQGDSVGLAAGNLDGNTSGKDQLILLYARSSQNQKHTAINMSILSYQKYDAKNPDKTFSATVSEKELRGGFSPLHNMTGGARDTVSPLEVQIGDFDADGYKELAFTFADSGSERCKLTLNIFKWSDPTGNLDVNTGTLCAYNLNDNGIVMGTNGNAHHSFAAGRYSYAGTAASGGATVMDQLGVVAAAWSTYESQQLCSGIFTWNKTDGLDRKAFKIDPDMHGAYYCVPRAAAADIHKESMVLGTPLAIAVTDRVDLYSAIQAPPRHWDAVSADESSTLSRDENGNAIADVFYRLSGYSTKIDTSKSSSSMVTKSDTHEGSAGITTGMKVGQFNVNGSKADPNFAWSLSVANEHAKTKTSKKSFSVEMDTSATAALDDQLYANTCDATVWRYPVIWPEDLRMSAVSDDKGNNVKTQNFIQYVVPERVGGNLFPVSGRNASWYNPNHDNRNLFTYPRQLKQTKGYPGTMKDVWGDEPEDLTGLLLAEQDAVYFGNVDAASAACSINTAQHKEAMEKNKLSVTTSVYGGGDIKPKAVPIYVTIYAQLDGNYAWTHSCTTTSDISNTSGVSIHWPGAAGYVSKSGIAPEQLGFKGDFGIYTQDDGVLCASYAVRLLKDDNSGSLLWGPSSPYRKKADPALNLPNRWYSDGTRNTLRSGGYVRGLTFAVKNEAGVKIERSYSNTGTLLPTNAKIVGKLRVFNLSFKEAANVTLKVYREPTASVSGVVSDPDLSRAELINTVNIPSIPGRDSYDESGYLDNWTDREFEFKTSGEEKAYWLHFKLESAGEELSGDNNYGYIMIATQNEGEGTKKFAAELVDPDKLPDLALSGVTVRECDGDKPGLETTLAEQIPLAGKSFNVSGHAAFTAGHVGTTKCDIIHGVTVNVVADGSVIGSDFVPGIEDAYNFSLNFAIPEGYKTPKEIKLVALSSQIPSAYDKDPENNGVILYSSGGSSGGCSAAGFPALAALLATATMVLPRRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8Y2</accession>
    <name>A0A011A8Y2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_4_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018833">
        <property type="entry name" value="DUF2437"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10370">
        <property type="entry name" value="DUF2437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2437" evidence="2">
        <location>
            <begin position="9"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="260" mass="28590" checksum="68FC106FE23509D2" modified="2014-06-11" version="1">MAKKSAPVRYCRFMVDGRSYSGQLRGGSVDIVEGDPFSGIISQIRLSYPVERVKFLPPFAPKKLWCIGRNYVGHVKELEHDIPEEPMVFLKATSAIIGANDFIRIPAWAGVIHYEGELAVVIGKAGKNISEEDAYDHVLGYTIMNDVTARALQNKDGQWARAKSFDTFAPLGPALLLTKELPKETRVVTRLNGKVVQDGAIEQMIFPIPRLISHISRFAALEEGDIISTGTPQGVGEIKAGDLIEVEVEPIGMLKNICSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A910</accession>
    <name>A0A011A910_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Citrate lyase alpha chain</fullName>
            <shortName evidence="1">Citrase alpha chain</shortName>
            <ecNumber evidence="1">2.8.3.10</ecNumber>
            <ecNumber evidence="1">4.1.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Citrate (pro-3S)-lyase alpha chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Citrate CoA-transferase subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + citrate = (3S)-citryl-CoA + acetate</text>
            <dbReference type="Rhea" id="RHEA:19405"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57321"/>
            <dbReference type="EC" id="2.8.3.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>citrate = acetate + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:10760"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="EC" id="4.1.3.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.10" evidence="1"/>
    <dbReference type="EC" id="4.1.3.6" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441877.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.677"/>
    <dbReference type="HOGENOM" id="CLU_046521_2_0_0"/>
    <dbReference type="OrthoDB" id="1099538at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009346">
        <property type="term" value="C:ATP-independent citrate lyase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008815">
        <property type="term" value="F:citrate (pro-3S)-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008814">
        <property type="term" value="F:citrate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006472">
        <property type="entry name" value="Citrate_lyase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40596">
        <property type="entry name" value="PTHR40596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04223">
        <property type="entry name" value="CitF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009451">
        <property type="entry name" value="Citrt_lyas_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01584">
        <property type="entry name" value="citF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="520" mass="54672" checksum="D4D6C9821D2290F7" modified="2014-06-11" version="1">MKTAVNSLGRTVPLEVPGVGAFAPYSTPFGRISSLAGLYTKPRTIRAAMPCRDKRAASLRAAIEKSGLTDGMTISFHHHLRNGDAVIPMVLAELEAMGFKNLTFAPSSIPDSHDCVADYIKSGLIGRLYTSGVRGKLGKLLSSGEVDIPVIIRSHGGRARAVEEGSIKIDVAFLAAPACDCLGNINGTEGPSACGSLGYAITDAKNAAHVIAVTDNLVQYPLSPKISIPQYLVDQVVVVGSIGDPAKIATGAARITRSPVDLRIAQDSFRLMKAAGIVEPGFSFQMGVGGASLAAAVYLEEYMADKQITGSFGLGGVGGYMASMHDKGMFRTVFDVQSFDAAVTKSMISNPSHIEIDASWYANPFNAGALVNNLDCVILAALEVDTDFNVNVLTGNDGVLRGASGGHQDTAAGAKLSIIVCPSFRGGVPSVKDRVTTITTPGETVDAIVTERGICVNPRRAELLEAALKAKLPVTEITELKKEVEKLTGVPEPIEFDYGKLLAAVEYRDGTLIDGVYAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A951</accession>
    <name>A0A011A951_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Anaerobic ribonucleoside-triphosphate reductase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710467.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.723"/>
    <dbReference type="HOGENOM" id="CLU_078147_2_1_0"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012840">
        <property type="entry name" value="NrdG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01094">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02495">
        <property type="entry name" value="NrdG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="19"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="229" mass="24993" checksum="37089244CA6631DB" modified="2014-06-11" version="1">MEKTADTRAGGYLPASFLDWEGHVAAVIFTCGCNFRCPWCHNGELVTARAGELSIEKIIFDIKRRAKFLDGVVISGGEPTLWPGLRPLLEELKALGLSVKLDTNGTNPELLRGLIRDGLVEHVAMDVKAPLDAESYAKLTGVPVDIAKITESVGIIKESAASYEFRTTFVPALHGPDDMPAIRAQLGDDRHWVVQCFKPSGCLDGKFLEKEAADPEKLKKILPGVRIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A955</accession>
    <name>A0A011A955_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type branched-chain amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710477.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.728"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OrthoDB" id="1475841at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="234" mass="25408" checksum="CE49B12AD15883CE" modified="2014-06-11" version="1">MLKVENLSVNYGGIQALRGISLDVPIGKIVTLIGANGAGKSSTLRAIAGLVRNKSGSVTWKEKHLMGLQPEHVLERGIALCPEGRRIFPHLTVLENLKLGGYSCKNKDEEAAGIERAFTLFPRLRERSWQKGGTLSGGEQQMLAVGRALMSDPELIMFDEPSMGLAPILVEEVFNIIEQINKEGKTVLLVEQNAFAALKIADYAYVLEVGEITLQGPGDELLRDPRVVSAYLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A967</accession>
    <name>A0A011A967_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/proline symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441949.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_3_0"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="475" mass="50524" checksum="A32CA4A17E5D1F94" modified="2014-06-11" version="1">MHELQYVPAMLWVVIAYMLAMIAVGGYFYNKAKKAGNESKEDFLLAGRSLGKIVIIGTIFATYLGGGTVTGGGNSLAYNFGIWPGICFMLPPIFSLSVLYLLSEKIRESGCYTIAELLEKKFGSTARTIAAAIIAISFISIVSFQYRGLGFVLNTTTGLPITSCTIICAVIVIILAYSGGLKTVATTDAMSAFLMLIGIGAAVPMLLSKVGGIEWVRATATADQLSFLGGQSFWGWLGAYLPLTFLTIGDQNFYQRINAAKDLKTARAGLIGCLAASLVVMPLIACISFIGRLYFGSNIAAGQSLIATASLLPVFWGGLLLSAASAFIITTADSFLLSASSNFTVDIYTKVINPHASEREQMWATRLFIAGAGVLAYVILQFYPSILAVQYMSYTISGCAITPAVVSVLVWPKVTKFGGIASMVCGTFATVIWEVLKYPYGVQTIYVALPISIIVLLVGSLCTQPKTGACAADNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9T6</accession>
    <name>A0A011A9T6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR04076 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442139.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.958"/>
    <dbReference type="HOGENOM" id="CLU_160502_0_0_0"/>
    <dbReference type="OrthoDB" id="1825724at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023811">
        <property type="entry name" value="CHP04076"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04076">
        <property type="entry name" value="TIGR04076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="114" mass="12829" checksum="ADF26B761922B1BA" modified="2014-06-11" version="1">MKKVKITVLKTTLDKELAEEYGAEGLGPCPMLREGQTFHADYAKPEGFCDEAWKAIYQYVFALAHGSGNGLFYYGDWIRKPGVAICSCNDGLRPVIFKLEATDEDSRIDYEPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9Y4</accession>
    <name>A0A011A9Y4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710959.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2011279_0_0_0"/>
    <dbReference type="OrthoDB" id="2150991at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="123" mass="13493" checksum="21539F3C1F1C003A" modified="2014-06-11" version="1">MERTQKTLRYTALCLLASLMLFSIIGNFEGPNDPYRMAFGGSWAETASSVDTVIQNGGPVMLSALQSFVQTGRKMTKDGPGSFALSTICMEADPCQAGLRQPLFSAKNFSPEERYINTIKKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA13</accession>
    <name>A0A011AA13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsE</name>
        <name evidence="11" type="ORF">Cloev_0996</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711013.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1065"/>
    <dbReference type="HOGENOM" id="CLU_065898_2_2_0"/>
    <dbReference type="OrthoDB" id="1505038at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="10">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="172" mass="18595" checksum="DEF81BFBC5E4C18B" modified="2014-06-11" version="1">MARETQNTKSYSSRGLELSERIVSINRVSKVVKGGKRFRFSVLVVVGDGVSQVGLGMGKAKEISVAMKKGIEHAKKNMIDLKKTGHTLPHPIIGKFGAAEVLMRPAAPGTGVLAGSSVRPIMELGGIKDVIAKVTGRTSNPINIAYATMDAVKRLRTPEEIYRLRGKERKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCF4</accession>
    <name>A0A010YCF4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ORF">Cloev_0004</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441196.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.5"/>
    <dbReference type="HOGENOM" id="CLU_007831_2_2_0"/>
    <dbReference type="OrthoDB" id="146811at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="8"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="400"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG77910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="626" mass="69468" checksum="BB377EB33511D1C1" modified="2014-06-11" version="1">MRINDRYDVITIGAGHAGCEAALAAARMGARTLLICLYLDSIAMMPCNPSIGGPAKGHMVREIDALGGECAAAADDATRHLRWLNTSKGAAVRTLRAQCSPRRYSDHYRAALLSEKNLELHQAQAAELVIERGEARGVKIKTGQIFYADCVILATGTYLDSKIHIGMTCHKSGPLGMVASTEFARSLRKSGLEIGRLRTDTTPRLHFDTIDWDSLDCQRSIAEPQAFSHFGPKRVYDEMICGLTRTNAETHRIIKKYFSESPLYMGRLDTEGPRYCPSIDDKIMKFPEKDTHPIFLEPISSEGREVYVQNFSTSMCLEAQFESIKTIKGCEHAHILRPGYAIEYDFVIPTQLNPWLETKPVKNLFLAGQINGTSGYEEAAAQGLIAGVNAALRVKGEEPFVLRRDEAYIGVLIDDLVTKGTGEPYRMLTSRCEYRLLLRHDNAAARLCGAGRRVGLLSDEKYGRFRAMAEAGEAEEIRLEGLKIPPTAEVNEKLAAISSSPLDEGISAKNLLRRPEVSWAFIAALTGSELDPEYGEKIANELKYEGYISRQQRQVEKFRRMEQLKIPAYIDFGEIRGLSAEGCGKLEKIRPATLGQASRIPGVPPTDIQLLWVAIENGRRKQNEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCJ3</accession>
    <name>A0A010YCJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sodium/proline symporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Proline permease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the sodium-dependent uptake of extracellular L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28967"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708586.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_1_0"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005298">
        <property type="term" value="F:proline:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031402">
        <property type="term" value="F:sodium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015824">
        <property type="term" value="P:proline transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11475">
        <property type="entry name" value="SLC5sbd_PutP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011851">
        <property type="entry name" value="Na/Pro_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="523" mass="56355" checksum="8DDE096E10378F73" modified="2014-06-11" version="1">MNWALVSFFIYLAAICLVGVVTMRIGNTYEDFLIGGRRIGPWVSSFALITSYMSGYTYTAAPGLGYAGGYSVLWWATGDAPGNAMSFGLLGRRLRKYSELLGAITLPEYYEKRFNSPALRVIAALVILLTVSMHLVAQWTASGKLLSVVFGTEYFTGMLIGCVVVLLYTIMGGYLAVVYTDFIQGLLMFAGTQVLFWVALFKVGGFAALNDKLGAVNPALVTPWGPDMAYYGLLAAATPIILIIMGSFGMPHITIKHFSMRNPSTARQAMLITGVFVVLFSFVYYMTGSLARVILGEGLADVEQAGVKLWFSVLPPFWAGFLSSAAVASLMSTADSFLLLLVSTIAHDLLNRFSKHEIPEKKRLFISRVLVLLVAVLSFIVAMNPPALVFTIVIFVFGGMALAFGVPNLFSVFWKRTTAAGVIASMICSLFIYVGATLGNWNLLGLHPFIAGLVVAVAVLVVVSLFTEPPHKQTLALFDAASEYGDVPKAVAAGASAAVSCEARAAVNERREFFDKVLAPAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCL6</accession>
    <name>A0A010YCL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <shortName evidence="6">PBG</shortName>
            <ecNumber evidence="6">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="6">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemC</name>
        <name evidence="9" type="ORF">Cloev_0084</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="6">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441265.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.98"/>
    <dbReference type="HOGENOM" id="CLU_019704_1_0_0"/>
    <dbReference type="OrthoDB" id="1450400at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="7"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="8">
        <location>
            <begin position="225"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="6">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="299" mass="31909" checksum="4C39227267E8FEBE" modified="2014-06-11" version="1">MTDKRIIRFGSRRSALALAQTKLVMEAVALADPELEVALVAMDTSGDRNMKPFSEASDKFGIKGLFTQELEEALLSGAIDVAVHSLKDMPMNADPALPLVAYSKREDPRDALVLPEGEREVRGGVIGCSSARRRVQLAALYPGIRIEPVRGNVNTRLRKLGEGEFSALVLAAAGLKRLGLEGRIARYFDTDEMIPAPGQGILACQGRAGEDYYYLDAVRDREAAACAAAERAFSAALGGGCPAPVGAFASLAGEEIEIIGLYADESGKDIRRGSARGAVKESMIIATKLAQELSRGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCN3</accession>
    <name>A0A010YCN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441292.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_8_1_0"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="201" mass="22131" checksum="3F0A55C98B4BAC5E" modified="2014-06-11" version="1">MRICLIRHALSLANAENVWTGQRDVPLSPRGVAEQRAICARFAYPRAELYFSSPLARCTQSLELIYGREADYLPAALSECSLGVLEGRPYTNLDDDPNYTAWLAAPDRPVEGGESFNGFTERVCAGFEALLSRCRAAGVSTAAGTMHGNVMRALLHRFADRNIPHGEWRIPNGGMYVLDFKTDGSAALWSTAPDFLFAQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCY3</accession>
    <name>A0A010YCY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type uncharacterized transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040769_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="367" mass="39701" checksum="E3DDFB54B954558B" modified="2014-06-11" version="1">MIRLRFEPRLYNPPWVNVLIPVAAVIFGLFAGGVLFACLGVDPLRAYQEVIKGALGSSYGLSEIVTKAIPLTLTALGGLICYKMLIWNIGGEGQLCLGAIATVAVVRYFFVDNWAVMFVMMSAAGAVAGGLWCMLAGFLRARWNVNETITTLMLNYIGINLSEYFIYGPWKDPMSMGFPFTPNFPEAARLWIFGNTRIHGGIFIALAVALVFQVILKRSKWGYEISVIGENPRAARYAGINISRNILLVTFIGGAVAGLAGMSEMAGLYGRMSRGFSMGYGYTGILVAWLARLSPIYVPLVAFLMGVLLVGGDTLQVVMGLPLASLQILQGLILFSVLAAETLSRFKISMVHVEKESSALDGGRGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDF7</accession>
    <name>A0A010YDF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441524.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.371"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_0"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="318" mass="36295" checksum="6DBA42EF7EFAF7CF" modified="2014-06-11" version="1">MLKDIEYIYAVYQERSFSKAARRLFISQPSLSAAVKRIENELGLPLFNRSTNPVSLTEAGEYYINFADKIMETEREMQEHFAALAGGAPARLNVGSSMFFCSYVLPEIIEAFRARYANITATLSEGSSVALSERLREGALDFLLEAEQLDKNVFESVPWTVERIVLAVPASNPINEELSEFRYSFEEMAAESTDAPLKPAVPLERFAEEEFLILKKWNDIHRRSLAICKEAGFTPKVSMYLEQMMTAYYLVCEGRGIAFVRDTILDCLAPSDKVFFYRLDNSEASRGIYLSYKKSGVLSQVQRDFIDFMKTEKLSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDU6</accession>
    <name>A0A010YDU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441734.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_905210_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="307" mass="32925" checksum="8EFD3820F2F3F7B3" modified="2014-06-11" version="1">MGGYLKCVSPDSPNKYVVISEGDIGFYEDVNGSPKLATAITQLGLYSVTNGGTVRTEERFVTKYGMPQVFVSPRSVNIFNVNGIELDQEINIKSPVVAVDDAGRATFGVSGGLTKKTTGNGSLLVPRIEQRIWHDHNDFFDDFTSGEGYHDYVERFSAEWAVPVISAKSAVACARVYGNAMRTRLNPQQPTGWEYCTSSWNYSLRVGIGNGAGVFSWGTATTGVKPNNADPLLISASVSGSQSGSHVHVKVECSASQMNVITNSASFYSQWFGGNNPMIPLYVNCLPDEGDISASSSGGFTALVVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE02</accession>
    <name>A0A010YE02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xaa-Pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441802.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_4_2_0"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="148"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="368" mass="40334" checksum="44AAFE628333D917" modified="2014-06-11" version="1">MAAFGKMEQMVSLLKIAGCDAFFIAPSPDLEYICGLDCLPDERFKGLLVTNKGRFFFMTPKLYLEEMSAVAGDPSLCEVWEDHEGFVGAFINGCKKAGLESGKIAFNDAVRAVDMLKISAAMKGIVCCDGEELISPMRSVKSKEEISLLQKAAKVADDTLSEVVKHIRPGLSERQIAEKLTEIHDDLGKGICRHISHIVAAGPNAAMPHYNGCDRIIEDKDVVLIDFAGRYGGYFSDMTRTFFIGDPTEEEKNVYRIVLEAQTAGERAIRSGISAGEVDRIVRKVIEEAGYGERFPYRVGHGVGISVHETPFIKAFNKHILRPGNVFSIEPGIYLPGKFGVRIENLVAVADDGSALVLNKLPKSMLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE27</accession>
    <name>A0A010YE27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_6_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="211" mass="23881" checksum="50A9E3694557E425" modified="2014-06-11" version="1">MEIIILPTGVNNMIDKRASADHEITGLIAERWSPRAFSDRTIESDKVLSLFEAARWAPSAFNEQPWRFITASKGNPPEFEKMLSCLADSNQVWAKRAQLLMILVVKNSFDYNNKPNRWAMHDCGLALENLLLEAAAQGLQGHPMAGFSTEAVREYYGVPDGYEPLVAIAVGYVGEPSLLEGELKERELEKRERLPLDSFVFEGKWQQPREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE92</accession>
    <name>A0A010YE92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">Cloev_0662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441912.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.707"/>
    <dbReference type="HOGENOM" id="CLU_049382_0_1_0"/>
    <dbReference type="OrthoDB" id="1712450at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="290" mass="32228" checksum="1F56E9F7F2889667" modified="2014-06-11" version="1">MQNNDNYWWYITIKSEASQEDNLFSLADISESIGTELQELPDGNSRLRMYYRSNEEISVWRTKLIEAMMEFPGVEIEDWGKIENQPWNVAAEEAFPPLPVGRGLVVLAPWHKGTEPEDRLALYINPGSAFGTGYHESTQIVLELLEKYIRPGITTADIGTGSGILTIGALKMGAGRAYARDIDPTVIEEVRKNFELNDLDLENIDLATGDLLKDFDHTADILTANILLDPLTTMVADVPAVIGKEGVAIFSGMLEKEKPVFLEALAAAKMRVIEELVRGEWWGVAAKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEA6</accession>
    <name>A0A010YEA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribonucleoside-triphosphate reductase class III catalytic subunit</fullName>
            <ecNumber evidence="1">1.17.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.2" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.722"/>
    <dbReference type="HOGENOM" id="CLU_002707_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02487">
        <property type="entry name" value="NrdD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="707" mass="79713" checksum="600A341C870D1E68" modified="2014-06-11" version="1">MVEELMNNFGRQGHLFENKGESTDLALMVDALAQEERSPWDASRIRDALIIEAGTDPATAEGIALEVEDDLLKYGRSNVTTSIIREMVNVKLFQRGLEAKLADHSRIGLPVHDLETMMFNKNKENSNTSHNPESINLSIAEMVLKEYALTKVFSKDVADAHLKGDIHLHDLGMVNRPYCSGQSVAYTARYGLNIPSITSVSNPAKHADVLLAHMLKMTSVLQNHFAGAIGWDAVNMYFAPYTVGWDYDKYLQLAQQLIFEFNQLAGGRGGQVAFTDVNLYYEIPNHFRDVPAIGPGGKFTGKTYSEYDKESKMFLRALFDVYMRGDSRGQPFFFPKPLLHITDYFFKEEGWEECLDHACRLSSEKGNTYYVFDRGGVAKLSECCRLSFELTPEDLNEAKHPWKMRYCALQNITLNLPRAAYKANGDDGMLFDIIDEEMELAAKAHLQKRAFIKNILDLGVKGPLAALCVSHDDEPYLRMRKASHLIGILGLNEMVQAMTGAQLHESEEAETLGRAVIQYMDLKCQQLSERYGLKIVLEQTPAESTALRFAKLDLRAYPEIAKNYIKGNFESGEIYYTNSTHLNYKLVQDPIDKVTREGELHPMIKAGAITHVWMGEHKPDPKALASFVMKTFRHTENAQVAFSPEFTICNECSHMERGLSDHCELCGSEDVDGITRVTGYFTRTSSWNAGKRGELKDRARRPVEMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEQ8</accession>
    <name>A0A010YEQ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710763.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.875"/>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_0"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="29"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="389" mass="43964" checksum="2DC95D4EA396C729" modified="2014-06-11" version="1">MRDFICDKIKKIKPSGIRRLFDIANEIPDVISLGVGEPDFDTPWHIREEGIYSLHKGRTFYTSNAGLIELREEIGRFMKRKYDLTYDPKHEMILTVGGSEAIDIALRAILNPGDEVIYPEPCFVSYEPCILLSDGVPVSIELSAATEFRLQPEQLEAAITPKTKALLISYPNNPTGAIMEREDLEKLVPIIVKHDLLVISDEIYSELSYKDRHVSIASLPGMLERTIVINGFSKSYAMTGWRLGFACGPAHIMEYMLKIHQFGIMSAPTMSQYAAISALKNGDRDICTMAESYNQRRRFLMEAFREMGLPCFEPYGAFYVFPDISEFGMGSEEFCTKLLEAENVAVVPGSAFGACGDRHVRISYAYSIEELKEAMARIARFVERLRMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEZ4</accession>
    <name>A0A010YEZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442124.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.946"/>
    <dbReference type="HOGENOM" id="CLU_046404_0_1_0"/>
    <dbReference type="OrthoDB" id="714984at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="9"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="103"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="375" mass="42040" checksum="14B3E65EC37C4ADB" modified="2014-06-11" version="1">MNMQTSISQHFAILTDNRAENHIRHNLTDILTIVLCGVICGAEGFNDIELFAKCKQDFFESFLDLPNGIPSHDTMNRVMSALDPKQFSECFANWARSLSERLKGVIAIDGKTSRRSFKNTEHRDCLHMVSAWSSDNGIVLAQTATEAKSNEITAIPTLLDMLDIKNCTITIDAMGCQKAIADKIVSMKGNYLLALKGNQGGTLEMAEHLFKCEEKTDYAGVTHTSYATIEKSHGRIEKRNVAAIENNEKIDIAEFDKWKGLKSIIMVESTRESGTQSSVERRYYISSLPADAAEIGRSVRSHWGIENSLHWVLDVIFNEDAMRNRQKNSAANMAIIRHCAINLLKQDKSGKTSLRGKRLKAGWDNDYMIKLISEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF40</accession>
    <name>A0A010YF40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710957.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1420841_0_0_0"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="196" mass="22572" checksum="FD304A15A1618CC1" modified="2014-06-11" version="1">MAANSERIEMAELLDDEISSVRKPVNLFDKITVSFYSIVCFCMSMLLMLIISAATIMRYFLQMDLYGYEEWVKIFAFWLYFMGAGYGAFAGTHVSADLVQSYMRESRTKDAVIFIRTLITFSVTLLFTWYGWEFFIFGFMGPLGTFVALPRTVAWRIPLWSAYISIFLGLLSMSWYFMLEMIAAGKKLFLKGGNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF62</accession>
    <name>A0A010YF62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="12" type="ORF">Cloev_0985</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710991.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1055"/>
    <dbReference type="HOGENOM" id="CLU_058591_0_2_0"/>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="224" mass="25588" checksum="5F0EDEE08C7E56E7" modified="2014-06-11" version="1">MGQKVHPVGYRLGVIYDWESRWYADGKKYAKYLHKDLELRAWIKKRWAQAGVSRVEIERIGDVMRFTVWTARPGVVIGKQGAEIQAVREELQAMTGNRVMINIQEMKNPDVEAQVVAEGVASSLERRISFRRAMKQSIFRAMKSGAQGIKIQCAGRLGGAEIARTEWYLEGQLPLSTLRADIDYGFAEAHTIYGVIGIKVWIYKGEVMERKPIFEAEPVTKERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF83</accession>
    <name>A0A010YF83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative Fe-S oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711036.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125010_1_0_0"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="140" mass="16567" checksum="7831C04EDD619216" modified="2014-06-11" version="1">MHYWWERDGVRFECTACGRCCGGEPGSIWVTPAERARIAGELGIDEIALRKEYLTRREGRCSIKEMENYDCIFLERNSRRCKIYKVRPLQCRLFPFWPSILKDKKVWNFYANRCPGMNNGKYYSPEIIKKFLNLPSAEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFA6</accession>
    <name>A0A010YFA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="7" type="ORF">Cloev_1059</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711151.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1127"/>
    <dbReference type="HOGENOM" id="CLU_047155_1_1_0"/>
    <dbReference type="OrthoDB" id="1405357at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="6">
        <location>
            <begin position="28"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="82"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="198" mass="22340" checksum="E5FFC2069A6B0270" modified="2014-06-11" version="1">MAEITAAMVSELRARTSVGMMDCKKALVECAGDMEKACDYLREKGLAKAAKKAERTAAQGRMFTYVHNNAKLAVLLELDCETDFVARTEEFNTLGHEIAMHIAAANPTYIKPEDVPADVIEHEKTVIMAQAREEGKPEKMLEKIAEGRINKFYEENCLLEQKYIRNPDVKIKDLVVENIAKIGENIVVRRYARFMIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFE1</accession>
    <name>A0A010YFE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(FAD)-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711208.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1176"/>
    <dbReference type="HOGENOM" id="CLU_003291_1_2_0"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="463"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="543" mass="57165" checksum="C6A7D5F3783A87E9" modified="2014-06-11" version="1">MKILVIGGVAAGTKVAAKLKREDRGAEVRILVKDKDISYAGCGLPYYVGGVIADRGALIVNTPEKFSALTGAAVLTGKEAVSLDREAKLVTAVDTETGEREAYSYDKLVIATGASPVAPPFPGINLKNVFFMRKPEDAVSLRAAVDTGEIRRAVVCGGGFIGLEVAENLAAKGVRVSVIDMAEQILPGFDPEMAAYAERHLADHGIACFTGAKLEEIIGGEKVEKIRTDKRAMKADAVVLSLGIRPNTAFLAGSGIELAPGGTIKVDGQMRTNDPDVYAVGDCAMVTNRVTGAPAWSPMGSSANIEGRLAARVLAGEALSYPGVLGTGVCKLPELNVGRTGLTEAAAKEAGYDVVTVTAVVDDKAHYYPGASNFIVKMIADRQSGKFLGLQALGKGAVDKMVDIAVVALTLGASLHDLENMDLAYAPPFSTAIHPFAHTLNVLLNKISGGLDSFTPAEYAAGLADDYKIVDVSINPSLEGAPYVDLTKIAGPLPEYGTGDKLLLVCAKGKRAYLTQNRMKFYGYDNTKVLEAGHIFNEIDIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS69</accession>
    <name>A0A010YS69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484752.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="77"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="261" mass="28879" checksum="B9EE560CDBAFE065" modified="2014-06-11" version="1">MNKDKPACAAGGAQTADRALQILKYIAAEKGPVPIGLICQEFELNRTTAWRLLSTLVNNGFIDRDVSTKCYQLGLSSVLLCADAAAQNEPIIRHSRQAMEELAEITQESVLLAVPKYNCTVTIAQVQSPLSIRLRDYINTTSPLYGTSNGKMALSFLSEAELEKFLALPRPPFTPQTITDREQLIEEINKTRERGFGMILSELSESENGVSAPIIYDKRPVAFISVAGPSFRFTEKRMFEVAPALISACRRVEESFRVGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSC2</accession>
    <name>A0A010YSC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709214.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1966727_0_0_0"/>
    <dbReference type="OrthoDB" id="2128829at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="127" mass="13736" checksum="7FC1CC2D9E583998" modified="2014-06-11" version="1">MNESPRKRVWVVTRIDGGRAAAADVFDNGSDAENFAGEMSVDTNNLAGLFQVLESSLHSRDPEKYISVPESIEKLVGGLYNDLALGGGTGKAAEYIAAHKPELIDEAVRAARERIVEILKEKGLLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSE8</accession>
    <name>A0A010YSE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441341.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.174"/>
    <dbReference type="HOGENOM" id="CLU_022936_2_0_0"/>
    <dbReference type="OrthoDB" id="735109at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002823">
        <property type="entry name" value="DUF112_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01970">
        <property type="entry name" value="TctA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="497" mass="52787" checksum="37F5512D67878B4E" modified="2014-06-11" version="1">MDYTPFVEGFAVILAPKYIMYMFSGVFFGLILGALPGLTGTLGIALMLPFTYSMSPLTALVFLLSIYSGGLFGGAITAIMINTPGSPANIATMLDGYPMMKKGMASEALGLALTSSVIGGIIGCIFLLLITEPLATLSLKFGPAEMFMVAIFGLSVVGSLGNDPLKGIFSGLFGILLGTIGMNANGIERGTFGVLYLLDGIPLIPCLIGFLSLPEILSLISQQYVVSGKISNPSLLKILSAWKEIMKRPVQVISTSVLGVIVGIMPAAGATVASLLSYNQSKQLSKRRNLFGTGIPEGIIASETANNASEGGAMSTMLVLGIPGSASTAMLLGALMLQGWVPGPSLFIDHRDIIYASISSLFLQQFVMYIVGLLLCLCAAYVLKVPVRYLIPCVLMFMVLGAFANRNAFFDAGLMLVFGVLGYIMKANDFPVMPTVLGIILGPIADRELLRTVQMYSGNYFAAFQKPIVLVLLFISIASIVVPMILKHRDDRQGMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSI2</accession>
    <name>A0A010YSI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein UspA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441373.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_11_2_0"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="154" mass="17209" checksum="0DD559DED0F65EEE" modified="2014-06-11" version="1">MKMLIAVDFSPVGREAAFNGYHYAQRLGADVTFLHIVPAMASPLEGYNMHFYITPDARKTEEKVREAASQEVNKLTDEIKAKYGALPDGHKYDIRVNVADNPGSEIVRVADSDRYDIIVIGNKGYTTLERVILGSTALKVVNQAKCSVFLYRHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSQ8</accession>
    <name>A0A010YSQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydrophobe/amphiphile efflux-1 (HAE1) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441439.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.294"/>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_0"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="869"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="893"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="921"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="970"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1003"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1045" mass="113294" checksum="403279F3BDF25604" modified="2014-06-11" version="1">MFAKFFIDRPRFAMVISILMALAGVIAAFSLPVAQYPNVTPPQIQVSTTYRGADASTLANTVGAPLEEMVNGVEGMIYMNSTSSNNGQYQLTITFATGTDPDMALVRVQNRVSQVTPQLPSEVTAEGITVETSFSDTLGYLALLSPNGTYDELALMNYAYGNIRNTMKRVPGMGDVQVFGSKYSIRIWLDPARVASLGLSISDVAAAIQSQNKQASIGSIGATPGSDLNSPIVYSLQTRGRLSSIKEFDNIIVRTTEQGGLVKLRDIARIELGSETYNTHASVNGAPAAMISLSQAAGSNALDVMSAAKKTMEQLSQSMPKDMKLLINYDSTTYVKATIREILTTLIITFLLVVLVCYLFLQDWRVTLVPVAAIPISLLATFAGLAAMGYSINILSLFGLVLVIGTVVDNAIVVVERVTFIMDRDKCSPEAATIQAMKDVTAPMTATTLVFLAIFVPVGFMGGITGQIYKQFAVTISFSVVFSLIVALTLSPAMCAHMLREVKPAERGPLKWFNTTLAKTTRGYVRGATWLARRMIVTIVLLGAVIGACWLVSVTTPTSFIPDEDQGVIFAAVQLPEGATLPRTQAVVRPMATEIGKIKGVQDVMNIEGINIMGGNGENVASIVLPLKPWNERNSKELQLTSIVAQVRQIAAKYPQASTNVFTPPAIMGLGMASGLDMRLQSTMENNPERLAEVMKALLVELNQAPEFLYAFSSYTADTPHLYLDIDREKAELMNVQVGSIFSTLQTYFGSAYINDINIGTQVNRVMVQSEWNYRNNMDRIGGIFVRNANGEQVPLQSLMTLRKTLAPRAIDRYNLYPSAGITIVMKPGFSSGQGITRVAELSKKILPEGYSYDWSGMTYQEQNSKGDIIMVLAIALIFAYLFLVAQYESWSVPVPVILSLPVAMFGALGGLWVMGLSISVYAQLGILLLIGLAAKNAILIVEFAKEQREEHGLPLIQAAATAASERFRAVLMTAFTCVLGVLPMLFASGAGAASRKAVGTTMFFGMNAATIIGIFFIPALYVFFQGTRERVKGRVSNTVKREEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSS0</accession>
    <name>A0A010YSS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441458.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_28_1_0"/>
    <dbReference type="OrthoDB" id="1497607at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="158" mass="17433" checksum="530A448BA5F4C21F" modified="2014-06-11" version="1">MRKIIVKTERLRIVPLSIEELRLLHDGEPDDGMKQAYGEMMDAVRRSPGREEWGTYWNICLTSGTRVGGLCFKGAPDAEGGVEIGYGIDEAYRRNGYASEAVTGVIKWAAEQSGVRRVTAQTEEENAASEKVLLKSGFAKDGRGDEGPLYKIILVKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSU3</accession>
    <name>A0A010YSU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.334"/>
    <dbReference type="HOGENOM" id="CLU_072993_2_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="72"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="18253" checksum="08AB7F45A1EB007B" modified="2014-06-11" version="1">MMIKIIALSAILLSVLFTVAVREAKAEGREVPKVSPFPIGEENRGFAQYFSGRSWLAPLAADRRLNVPIFNVTFEPGCRNNWHVHTGGQVLIAAGGVGYYQERGKTARRLVPGDVVEIAPDVEHWHGAAPDSWFSHLAIECNPGSNKNTWLEPVTEEDYKAAAKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSU8</accession>
    <name>A0A010YSU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclophil_like2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708978.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.340"/>
    <dbReference type="HOGENOM" id="CLU_133050_0_0_0"/>
    <dbReference type="OrthoDB" id="1789664at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041183">
        <property type="entry name" value="Cyclophilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18050">
        <property type="entry name" value="Cyclophil_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458837" description="Cyclophil_like2 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclophil_like2" evidence="2">
        <location>
            <begin position="60"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="173" mass="18780" checksum="600E1AE072446E2C" modified="2014-06-11" version="1">MRKTFFSARLLSLLLVFAGCGVVGAACPAPAQAAPAPVKAQGAEKYSTRRIAGGTKVRLVVGDKVIPATLNDSRSAKELISRLPYTVSMSKYSHDYCGVMARPLSYDKKDVHNGWLNGDIDFATDGNYFTILYKDEDISKQFGFQVNIGVIDAPLSVMDTLPGSIEMRIELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSX3</accession>
    <name>A0A010YSX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441532.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.374"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_0"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="289" mass="32834" checksum="207024CEF4BF90C4" modified="2014-06-11" version="1">MNRYEVFVKVAECGSFTRAANELGYTQSAVSQMVHTLEEELSTVLLRREKGGVVLSADGEQYMPYIRSICAAHRELRVKCEEMRGLVGGNIRIGTFTSVSRSWLPKLMNEFKSIYPFVHFDLRQGDYRGIEEWISEGTVDFGFTCYDEVKGLVVTPLRKDEMLAALPPGHPLSGREYVTLGELSKEPLILLDEGEFSVALDAFRRENLEPDIHYRVTDDYTVISMVEQGLGVSVLYELVLKNEERSLAALHIEPPVERTTALAYRNKRTLSVAARRFIDFVLDHFRVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSX7</accession>
    <name>A0A010YSX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator-like protein with receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441541.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_14_3_0"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="268" mass="30109" checksum="58C870C8A2B8DB00" modified="2014-06-11" version="1">MKVIVVDDEELLLEDLLLQLQEVPSVISTVGFTDPEKALEYILHNEVHVAFLDINMCGMDGLTLAAHIQREKPAVSIIFLTGYGEYAVDAFKLRASGYIMKPANSEDIITELSNLRPVGPRHDLGRLRVQTFGCFEVFANGAPLRFSRSRSKELFAYLVDRRGASVSIAELASALWEERDFDKSLRNQIHTFMSDIVAALKAVGAAEVVIKHRNSFAVNVDGLECDYYRYLEGDPQAVKSFTGEYMANYSWAEYTTAQLVRNREEGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT06</accession>
    <name>A0A010YT06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Subtilisin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0379</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.416"/>
    <dbReference type="HOGENOM" id="CLU_011263_15_6_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458840" evidence="7">
        <location>
            <begin position="26"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="153"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="518" mass="54307" checksum="A10BEE8DC023DED9" modified="2014-06-11" version="1">MMKNYSISALILSLTILFFGSAASAADYAENQVIVLLRDSNAASSVMSASAKQSSAAKAASLAKSVGASALKSFPELTAGSGRSIALFSSEEKTADELISALKDTPEVIGVAKNYMRKALAEPNDPRWASQWGTKRIKAPEVWEAATTGSDAVYAAVLDTGVIYDHPDLAANISGKLPDGTYGKMFHDNGTVTDVVRSGTPSGDVTITNVNQVDYATVGDVGGHGTHVAGIIGAVGNNSIGVAGVNWKVKILPVGVFTVVEDKEEKSGWGTGAYDIDIIAALNYIVELKKTYGLNIRAANLSLGRWTEPVDQDKDPYAQAVKLAGDAGIIVCMAAGNEEQDIDAPTDPECVGKLSYPACFRFDNTISVGASNENDGLGKSSGSNYSTSGKWVDVMAPGDNIMSTTPFYSYAGSKDYHRDGYDSWSGTSMATPMVTGAAALLCAVYPDKTANEIKTMLMNGAENVLKDGYSKYGLLNVYNAYLLGRQEDSGSSSGGCSAGFAALALIVLLPLAMRGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT70</accession>
    <name>A0A010YT70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage terminase, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484833.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.510"/>
    <dbReference type="HOGENOM" id="CLU_064914_2_1_0"/>
    <dbReference type="OrthoDB" id="1645100at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038713">
        <property type="entry name" value="Terminase_Gp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005335">
        <property type="entry name" value="Terminase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03592">
        <property type="entry name" value="Terminase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="209" mass="22906" checksum="8E797D39CFCFBB87" modified="2014-06-11" version="1">MPEEVNLVRGKKLTPKQARFVEEYLVDLNATNAAKRAGYAAKTSYSIGQRLLKNVEVQNAINVAQRRRSIRTEISQDAVIKEIAKIAFGDPRAVMSWGPDGVKLKDSKEISDDAAAFVAEVSESTTESGGSLRLKTNDKLKALELLGKHFGMFKEQQPVQQSTNNLIFADSNALIYQAVLDTVRDTARAVREGAVLSGDPVREGDITEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT77</accession>
    <name>A0A010YT77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441717.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1445315_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="187" mass="20015" checksum="2D47E060F016A0CF" modified="2014-06-11" version="1">MSGFFEAGRKYRVRVTDLHSPDAVTFSVSLNNMTGRYYTNEDIEMPGELINVLLDATVPHEIIQMERGYPKIVGVKLRPRFSVTPLGMPAVPTADATLITPGVSAGTGVLGGEMPLPPSDDGVPLFDPHEGAEPEPEAEDGADRQAELTGMNKGALIEIAQGYGLRYTEKNNKSEMITGILAAEAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT95</accession>
    <name>A0A010YT95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="3">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709612.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.544"/>
    <dbReference type="HOGENOM" id="CLU_016755_1_2_0"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="6">
        <location>
            <begin position="4"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="5">
        <location>
            <begin position="342"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="455" mass="48839" checksum="F19B39F5675124C9" modified="2014-06-11" version="1">MEMYDVIVIGFGKGGKVLASTLAAQGQRVALVEKSDKMYGGTCPNVGCVPTKFLVHRAEISQIKGFPEFAQKAAFYRESILDKKELRKKILGKMFNMFDSNPNITLYTGTAKFVSPKEIEIRGKDFTAAATADRIVIDTGSVPFIPPIEGLGECGCAYTSEGMLDLEKLPERLVIIGGGNIGLEFASFYRQFGSEVTVLQDLPDFFPNEDADVAAAVKETMERQGVKFVFGVKVLSVKNDAEGAIVRYSAGGVEREAKGDAVLVSTGRIPNTRELNLAAAGVETTPRGAIAVDGNMRTSVSGIWAIGDVAGSPQFTYISQDDARIVMADFSGGGRTSAGRNVPYSIFLAPPLSRVGLTEKAALAQGYKTKTAVIPVTGLPRSHVLGRYTGLLKAVVDADSGLILGAALYCEESHELINIVTLAMNEKLHYTVLRDMIFTHPVMSEALNDLFGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTF9</accession>
    <name>A0A010YTF9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isoaspartyl dipeptidase</fullName>
            <ecNumber evidence="1">3.4.19.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 4">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Carboxylation allows a single lysine to coordinate two zinc ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.-" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710315.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.626"/>
    <dbReference type="HOGENOM" id="CLU_058216_0_0_0"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008798">
        <property type="term" value="F:beta-aspartyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010229">
        <property type="entry name" value="Pept_M38_dipep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001238">
        <property type="entry name" value="IadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01975">
        <property type="entry name" value="isoAsp_dipep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="53"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="266"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="69"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001238-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001238-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="390" mass="41291" checksum="2DABEEE4296DC811" modified="2014-06-11" version="1">MFVLIKNADVFAPEPLGISSILISHDKIAWLGKDFPAEKTLPDLEIIDAAGKIMIPGIVDGHVHVTGGGGEGGFATRTPELALSDMIKGGVTTVIGLLGTDDVTRSAGALIAKTNAIRAEGMSAWAMTGSYQLPVKSLCGGVRDDIALIEPFIGVGEVALSDHRSSQPTFEEFMRLAAAARVGGMLSGKAGVVNVHLGDAPSGLDYLFRAAKTEIPPSQFIPTHMNRNPELFKEACRYGAMGGYVDLTTSTTPQFLDEGEVECGRALSELLAAGVPARRISFSSDGQGSMPFFDEAGDFAGLTIGRVTSIFETFRSTVKNYDILFEDAVRVVSTTAADHCKLSGKGHIKEGCDADLILMDAGSLELDTLFARGRKMMSGGRPLVKGTFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU82</accession>
    <name>A0A010YU82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484876.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.894"/>
    <dbReference type="HOGENOM" id="CLU_017985_0_3_0"/>
    <dbReference type="OrthoDB" id="977094at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="54"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="440" mass="48347" checksum="F5BB6B2F142DC431" modified="2014-06-11" version="1">MAETSLFETGGEENISFEVPLAERMRPRTLDEYAGQGHILAPGRALRSMLDGGKAPSCILYGPPGVGKTTLVRLIARVTGRTLLEINAVSAKVETLRDLLERARGEKKLSGRSAIAFVDEIYHFNSKQQNVLLPAVETGDLILIGTTTENPWFEINKTLLSRMVVYTLEPLKNEDICGLLRRALDDTERGLGRFGVRAETETIERIAALAGGDARQALTRLEASVTAAAMGGGSLLTDEIVAESTGAATQRYDRNSNDHYAVISALIKSMRGSDPDAALYWLARMLEGGDDVRFITRRLCIFAAEDVGLADPMALVVTQNAAAAVDRVGMPEANLILGEAVIYLASAPKSNSAYLAIKAAQQNVREGKIMEVPSHLRNDGEGYVYPHDSPNHWVPQAYMPEVRRFYFPGKLGAEARIEDRLKRLWKRFSTEAEEKQDKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUF2</accession>
    <name>A0A010YUF2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="3">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Spermidine synthase</fullName>
            <shortName evidence="3">SPDS</shortName>
            <shortName evidence="3">SPDSY</shortName>
            <ecNumber evidence="3">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">speE</name>
        <name evidence="8" type="ORF">Cloev_0897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 6">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer or homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710892.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.960"/>
    <dbReference type="HOGENOM" id="CLU_048199_0_0_0"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="PTHR11558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="7">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="3">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Spermidine binding" evidence="3">
        <location>
            <begin position="155"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="283" mass="32711" checksum="BDD91BFCD4EA3E2C" modified="2014-06-11" version="1">MELWYTEEHTPTVRFSIKVKKQLFGGKSPFQQIDVFDSEEFGRFFTLDGLMMLTEKDEFIYHDMIVHVPMATNPDVRRVLVIGGGDGGTVRELTRYKTIEKIDMVDIDEMVVKVCRELLPFTSRKLGDPRVTLYFEDGLKFVRTASEKYDLIIVDSTDPFGPGEGLFTKEFYGNCFKALTDDGILVNQHENPYYDSYRASMKRAHQRIEDFFPVCRVYQAHIPTYPSGHWLFGFASKKFDPIKDLDAAAWNGLGLETRYYNTDLHVGAFMLPNYVKQALELKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUG9</accession>
    <name>A0A010YUG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar phosphate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.989"/>
    <dbReference type="HOGENOM" id="CLU_001265_62_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="410" mass="44874" checksum="DBF687FE682D47BF" modified="2014-06-11" version="1">MRKTNSDAINYFIYCLLAFSYFLACFLRTSSGVILPHVAASIVLTPSAIGLVSGMFFYGYTVTQPFCGKMCDEKGPLFIESCGLAIFAFGLFLFAIARSTTSLCFARFLIGIGAGPTFCGIMVFQAKAFSPSIFSKLMGYTIMLGHFGGVVSITPLGVAVDKYGYRAIHSTLAVLVLLIACSLYYLRRNFTISCAKAEKASGVLSGFMIICRFSQLRSILFLWSLGMLLQMNLIGLWGVTWIAKSGNIAVSSARFYMSMAGSGVLVGAFLCGRYGNDLVKSPKYIRWICLLLISILLSLTMCIDFCLAWPLLLSLSLCLGVILGMTNVLCNIYLYKIVGPDLVGTVTGANNVILFLAVLFSQWFSGVFIQEYDNLIDITYVSSYAAFFLIISMLGVFALHMLCKTSFNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUQ6</accession>
    <name>A0A010YUQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Shikimate kinase</fullName>
            <shortName evidence="7">SK</shortName>
            <ecNumber evidence="7">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroK</name>
        <name evidence="11" type="ORF">Cloev_1039</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035008_1_1_0"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="111"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="300"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="390"/>
            <end position="395"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="551" mass="60979" checksum="01C4B6C232227B8E" modified="2014-06-11" version="1">MLKEYREEIRELDEKILALIERRLEAARAIAEYKMDRNIPITDAAQEESVIDHVVSLAKREDDIPYIRRFWRMMLENSRAVQHKVVTGDNITGLWLREMIRAAARRKENPQVIYRGCEGSRGHEAAEAYFGGEARFGNAATYEKVCRSVKNGTADYAVLPLESNTAGAMAGVRELINKYGLCIAGEQNVRLDDCLAAPRGADIGEIREIYAHEQVLARCTAFLEDHPEIKAVPSLSSAKCVRKVAEEGSPRGAVITSGFAAEMSGLEVIAPYISDNPGSCTRFVILSNKFEISPGCNKVSIAFTVRHRAGALQRVLGVFADYHLNLSKIESVPVGGADFEYLFFADFAGDLAQANTQKALALVEQECDSLRVLGNYKSKRRNIVLVGMPGSGKNAVGKALALQIGMDYYDTDALIEEREGMSTTEIFAKKGEKYFRDAETEIAKEVSCLGGAVISTGGGTMMRQENARALRRTGYVFFVNRPVEEILASVDLSNRPLLAGDPKHIFKLYTDRLPTYREVSDYEVRNDGELSQAVNMLDSIIELLKGGYRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUR4</accession>
    <name>A0A010YUR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/pantothenate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_1057</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711142.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1124"/>
    <dbReference type="HOGENOM" id="CLU_018808_15_1_0"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10327">
        <property type="entry name" value="SLC5sbd_PanF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011849">
        <property type="entry name" value="Na/pantothenate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02119">
        <property type="entry name" value="panF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="492" mass="52590" checksum="315EAEAD43F2A145" modified="2014-06-11" version="1">MVDHTGMIIPLVLYFILIMGIALWGSRTAGKRSDTKGFMEEYFIGSRSMGGFVLAMAIITTYTSASSFVGGPGVAYNVGLGWILLSMIQVPTAFLTLGVLGKRFALIARRTDAVTITDFIRARYGSDAVVILASLALLVFFMASMLAQFIGGARLFESITGYSYQTGLLIFGFTVVVYTTVGGFRAVVLTDTIQGVMMLFASLAILYAVITAGGGVENIMQTLYSIDPRLLTPTGGGNAIPKPFILSFWVLVGIGILGLPQTTQKCLGYKDSRSMHNAMIIGTFVVGFTMLAMHLVGAMGRAVIPDITVGDLAVPTLTVRLMSPFWAGIFIAGPLAAIMSTVDSMLIMCSAAIVKDLYFHYVVKNDEARLSPKKVRGMSVIVTAVVGVLVFFAAMKPPSLLVWINLFAFGGLEAVFFCPTLFGLYWKRANSTGAVLSMICGASAFFWFNITKTSVGGTTAIVPTLAIAVAAFVAGSLLGRPESAEKLKMFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUU1</accession>
    <name>A0A010YUU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_1083</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442388.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1152"/>
    <dbReference type="HOGENOM" id="CLU_022986_0_1_0"/>
    <dbReference type="OrthoDB" id="871298at2"/>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="PTHR12561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00545">
        <property type="entry name" value="lipoyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="8">
        <location>
            <begin position="30"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="330" mass="36309" checksum="256EAE1BA83D0527" modified="2014-06-11" version="1">MINRAVFVIADGAVPYRNQAVEEYLMRTVEAGSCVLYLWQNQRTVVIGRNQNGRAECRVELLEKDGGYLARRLSGGGAVFHDLGNLNFSFIAADPDYSVARQQGVILAAVRSLGLSAELSGRNDITVGGRKFSGNAFMSSGRRHCHHGTLLISADTSDMAKYLNVDKDKLESKGVRSVRSRVVNLSELDGGITVETMTSALREAFGGEYDVEPENLAVSDLDEALLDSMTQKFASPEWRLEAEPDFVFRRKRRFDWGGAELCLTVSEGNVTAARLFTDALDPDFSETVEKTLTGAAFTTDSLRGALIGTNCREERERMLLDISSLLMEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUX7</accession>
    <name>A0A010YUX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-binding protein, possibly nucleic-acid binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484914.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1194"/>
    <dbReference type="HOGENOM" id="CLU_100236_1_1_0"/>
    <dbReference type="OrthoDB" id="1665714at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="194" mass="21833" checksum="9347023E2408D440" modified="2014-06-11" version="1">MEKYLEAAPKSWKHRLVLSAVPKDGAPYEDSFSVHLDRPVSYWDQIYTLLSDPLVKVESCRSEGRVVVIVSLRTEVGVPCARCLEPARSEIGGELRYIFSLRRDERQREESEEGQDGEEEMIVLDSWEDEIDLGQLIWEVLITALPGAVLCSPDCKGLCPQCGANLNKAPCGCKKESRDPRFDVLKNFMADNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUZ9</accession>
    <name>A0A010YUZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442457.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_1_3_0"/>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="132" mass="15287" checksum="5C5FF862C7D06896" modified="2014-06-11" version="1">MIMTRETDYAVRILRALSCGERMTVRQVCDLELVPVQFAYKILKKLAACGYVEVFRGQEGGCRLKADLNELSLYDLMRCINDDIFVNACMDPGYKCPWRRSHCGVCHFHSSLKGVQNEIEELLKRWYIGKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGR1</accession>
    <name>A0A010ZGR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441205.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015320_4_1_0"/>
    <dbReference type="OrthoDB" id="1808930at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459089" description="Ysc84 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84" evidence="2">
        <location>
            <begin position="104"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="232" mass="24009" checksum="538A00E9172342B1" modified="2014-06-11" version="1">MKFSRKIMIFALLALLVAGAAQAAFAETAHMRRIRLSADLINKMANEQDADALADVIKSGKGVAIFPAVTKAGLGIGGQTGEGVVFLRQSNGRWSGPAFMGISGASIGFQIGVQSVGLVLVITNEQGLRAFTGGNSFKLGADVAIAAGPVGRDASAATDGRAKASIYSYSMSKGLFAGISIDGSVINQNRDASKAYWGRDISAANALKKPATDKRVAPLIKALNNLVKKAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH55</accession>
    <name>A0A010ZH55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Citrate lyase acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709252.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158489_2_0_0"/>
    <dbReference type="OrthoDB" id="1966288at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006495">
        <property type="entry name" value="CitD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023439">
        <property type="entry name" value="Mal_deCO2ase/Cit_lyase_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06857">
        <property type="entry name" value="ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01608">
        <property type="entry name" value="citD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="92" mass="9758" checksum="BE96B5A32E58836E" modified="2014-06-11" version="1">MKTSQAGTLESMDCLVTLTEAESGAGIKITITGASAARFKSAMEKKITETLEELGVKDIEAAVQDNGALDIVLGARVEAAYKRLLKQKGEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHD1</accession>
    <name>A0A010ZHD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090588_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013668">
        <property type="entry name" value="RNase_R_HTH_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08461">
        <property type="entry name" value="HTH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FCD" evidence="4">
        <location>
            <begin position="127"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="256" mass="29121" checksum="8AF61CB9DACCDABB" modified="2014-06-11" version="1">MTGGCRILSAWAGYVTDMGVFDVLQSHDNVIYNILLFLKETNEPAGAGSVQRFLEKKGFSMAEATVGRVLRDMDCAGYTEKRSNQGRAISADGEKRLRELEEMRWHDKWTEGFLDVFERTDKNYLLDLLEARLPVETTVARLAARRASAEETEALRAVVKEQERLAKRGAPVSALDDEFHRTLAAASHNQILEAIVELLRKKEEYGRAFEKIRRDAGHIYNSEHRKIFEAIEARDPELAELTMKRHIANLIESVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHD8</accession>
    <name>A0A010ZHD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Co2+ transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709379.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_905209_0_0_0"/>
    <dbReference type="OrthoDB" id="959554at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019613">
        <property type="entry name" value="DUF4198"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10670">
        <property type="entry name" value="DUF4198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457921" evidence="2">
        <location>
            <begin position="34"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="307" mass="32664" checksum="8DF76215871BA12C" modified="2014-06-11" version="1">MERLFKMAAKYKSGAGALALICALFVCPPAADAHYFSVIPKVSRTGVGNEHSVIVSFTHITKQAQYDYSFMKLDPDADMLNGRLIYKDGTETDLTNLFAAYDDPDGDEVTGIDSRRAVAPIGKEGTVIAACRTNLNIPGQMVYTGYSKHIFNTAADGHSTKAAGGGEVAEIIPLSDLAMATVGVPIKFKLLYKGSPREGAEIEYGNETTPIVKGEEGPENLKKLETPSDKEGIFTYTPDSAGRNTVAAMLDLGNKTYCSTTLSFEAKERSGGGSGGCNAASALPALLVLLGLSLAPVIKKRIKNNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHT8</accession>
    <name>A0A010ZHT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integral membrane protein CcmA involved in cell shape determination</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441549.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1270459_0_0_0"/>
    <dbReference type="OrthoDB" id="1296777at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="PTHR35024"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="217" mass="23136" checksum="79DBDA121AFCF860" modified="2014-06-11" version="1">MDYRQNFKTALKEIFLLQKSQNREERPAEKQDIAAFVTEAETAAPKLALTQPRKNDRKKSDPSVISEDTAINGEVVSKGSLDIRGIIVGNVVTKGDIVISGSVEGNISGENIDLKACKITGDLAAEGTIKIGKDTEIVGSMMSKEIFVDGKVSGNISSSADAYFRQGAFVIGNVTTNMIAIERGGVICGEVTIGSAALNGDPQNRSEEARMRIQAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHV5</accession>
    <name>A0A010ZHV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4 5">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gpmA</name>
        <name evidence="6" type="ORF">Cloev_0380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4 5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441574.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.417"/>
    <dbReference type="HOGENOM" id="CLU_033323_1_1_0"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="249" mass="28205" checksum="DB70A1CBDC5969D7" modified="2014-06-11" version="1">MYKLVLIRHGESTWNKENRFTGWQDVPLSEKGLAEARAAGGLLKKEGYLFDKAYTSVLRRAIKTLWCVLEETDLMWIPVEKSWRLNERHYGALQGLNKAETAAQYGDEQVKIWRRSYATRPPLLTKEDERWPGHESRYASLSPDELPLGECLEDTVARVVPYWEKVVAPDVRSGKKLIIAAHGNSLRALVKYLDDVSEKDILELNIPTGVPLVYELDEDLRPLKHYYLGDAEAIAAAQAAVAKQGSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHY1</accession>
    <name>A0A010ZHY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycyl-radical enzyme activator family protein</fullName>
            <ecNumber evidence="9">4.2.1.30</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0416</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.30" evidence="9"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441624.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.459"/>
    <dbReference type="HOGENOM" id="CLU_058969_0_0_0"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046405">
        <property type="term" value="F:glycerol dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040074">
        <property type="entry name" value="BssD/PflA/YjjW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01118">
        <property type="entry name" value="activating_enzymes__group_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="16"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="301" mass="33119" checksum="23C6A695A51D6381" modified="2014-06-11" version="1">MSKTGIIFDIKKYSIHDGPGTRTTVHLKGCPLACWWCHNPESQSVMPTVLFRGEKCIGCGSCVRSCPHGAISARGGTLVTDDGLCDGCGKCCDVCPPEARELCGRRYTVEELMTQLHKDEIFFRDGGGVTFSGGEPFMQPEFLLEALDACGRAGYHRALDTCGFVSRSVIVDSVKRADLYLYDVKHMDPERHKEYTGVDNVVILENLRAISDAGAKINIRVPFMPGLNSGDENMHALGRFVRPLKGITGVNILPYHTVAKGKHDRWHMEYKLGDLLPPTENQTRHAAAILESYGLKVHIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHZ6</accession>
    <name>A0A010ZHZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441651.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2681168_0_0_0"/>
    <dbReference type="OrthoDB" id="2203416at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="74" mass="7814" checksum="E5A9FCBA1C343B86" modified="2014-06-11" version="1">MRDGTKNGIFFIDAIEGNTARLLPEKGGAVEFPASLLPAGAREGRRVEISAKLLCDSGDRAEIDSLLGELGDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI88</accession>
    <name>A0A010ZI88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0543</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441793.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.582"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="332" mass="36028" checksum="C0D72259E9F82A11" modified="2014-06-11" version="1">MPPVVVQTEHLTKKFGSFTAVDDINMSIEEGEVYGFLGPNGAGKSTTIRMLCGLLAPTSGKGLVLGLDLASNGQELKEKIGYMSQKFSLYPELSVLENLNLYSGLYGLTGAAKKKRIDEMLDLAGLVGRENEPTSALSGGWRQRLALGCAILHKPKILFLDEATSGVDPKARLLFWDIIYDLAADGTTVMVTTHFMDEAEHCNKVAFIYYGRLIADDSPDNLKKKIPGKLYEVTADDPMALLAKVQAGEDGPVIDSYFFGDKIHLLVSPDREITAEGIFAESKIERIEQSMEDVFVYLVKSHAGDDLGSGRISGIGNITTSQAKGAEKEGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIC3</accession>
    <name>A0A010ZIC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441833.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.627"/>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_0"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="258" mass="27452" checksum="5EC9653AC193FAB1" modified="2014-06-11" version="1">MQDKIVAVKKEGAVAWVTMNRPGSLNSLTAELCAALKQALAECEADDDVRVVVLAGEGKAFCAGGDLRTILELSDYEAARKYVRAAGEITAAVMRSRRPFIAMVGGAAAGAGFNIALACDFICASKRAKFTQAFSSIGLISDCGGNLLLPRLVGPHAAKRLMMLPATLSAEEAQALGLVTELAEEADLREKTAALAARLAKQPPLALAQTKKLLNDCEGLEKTLRNEEDIQAELIIGEDCKEGVRAFFEKREPGFKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIQ5</accession>
    <name>A0A010ZIQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710553.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.749"/>
    <dbReference type="HOGENOM" id="CLU_013985_21_0_0"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="147" mass="16929" checksum="69CA2A51DFECF326" modified="2014-06-11" version="1">MTITEITKRDEAAIQRVSFIWEKSVRATHLFLTEDDMLDISKDVDDALASVPTLLTAENENSEPVAFMGIDGDRLEMLFLLPEERGRGLGEKLLRHAIDKYSVSRLCVNEQNTSAFGFYEHMGFKVYKRTERDEQGHPFPLLYMKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIT1</accession>
    <name>A0A010ZIT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved protein of DIM6/NTAB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710603.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.771"/>
    <dbReference type="HOGENOM" id="CLU_059021_4_1_0"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="9"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="174" mass="19214" checksum="BFCD52FB2456E404" modified="2014-06-11" version="1">MGNIDMKALFSLTYGMYIVSTDLEGRLNGQIANTVMQITSEPVCVATCLNKANLTTDMVAKSGRFSVAILEQDVPMTFIGQFGFKSGRDIDKFENVKYSLAGAGTPLIEEWSVAAFDAKVVRTIEMPSHMLFIGEVEESVYFKEAPLLTYSDYHKIKKGKSPKTAPTFGFNTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ65</accession>
    <name>A0A010ZJ65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-glucan phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.890"/>
    <dbReference type="HOGENOM" id="CLU_285433_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011834">
        <property type="entry name" value="Agluc_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021923">
        <property type="entry name" value="DUF3536"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12055">
        <property type="entry name" value="DUF3536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02094">
        <property type="entry name" value="more_P_ylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="4">
        <location>
            <begin position="41"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1085" mass="121981" checksum="5A479B95AE6A5073" modified="2014-06-11" version="1">MINIAIHGHFYQPPREDPWTGTIPRDPTASPAHDWNERVCSECYLPNSCARILGTDGRIKTEINNYAKLSFNFGPTLHRWIEAHSPSLNKTLIESQSRAIAQAYNHVIMPLASERDRLTQTVWGTEDFKYRFGRAPKGMWLPETAVDIPTLETLAACGVEFTILAPHQCKAVIVDGSPILTSRGANLDVTRPYRCELPSGRSITIIFYHAGLAQGIAFGGLLNNGDLFKDAAVRSAAEGEDRLLVTATDGESYGHHHKFGEMALARMFEQMELDERINLPSIEGFLAEHPPTASCIIEENTSWSCAHGVERWQSDCGCHTGGEPGWNQKWRGPLREAFDNLAAKTDELFEEKISVYGDPWKLRNEAVDLYKCGLAPSAEERAERRRAFVTERFGDLSEKVSERIAGLIEMERMRMFAYTSCAWFFNDVAGVETRQVISYALRAAQIAEESSGRDFIRPLLEDLRKARGNTRERPTAAAVAIRDIMPRMREQSDMKTKGEQNTDGSEKMNGMNYGTNLANSLLATLEHDPAFRNTAYFSMEIALMPEIPTYSGGLGVLAGDILKSASDLGVPMVAMTLLYKKGYFAQKINREGRQTEYPVEWNPRDFMTQLPNRVTITMNGRPVTVGAWCYMLIGQTEHPLPIYFLDTDLPENLPEDRLLTAELYGGDNKYRLCQELILGICGLRLLRDMGYRNISTFHLNEGHAGFLTLELLREQGYGDIEKVRNQVIFTTHTPVAAGHDFFSYDLIDEVMDGDVAQILRQHIGGNGLSMTDLALKLSRYVNGVSHKHALVSRAMFGNESIDWITNGVHSTTWTSPSFANLYDARIPGWRNDPSRLMQALHIPDEEIWKAHQAAKMKLLAFVLEETGQQLDPDVLTIGFARRAATYKRADLVFSDIRRLVEIGKGKVQFVFSGKAHPHDEPGKDILQKINRIAKELGAELPVVFIENYNMGPAKFITSGVDIWLNTPIRPREASGTSGMKCVHNGVMNFSVLDGWWIEGCIEGRTGWAIGPEPTENGMVEYNEAEDAVDLYNKLEEKIIPAYYTDRKRWIGMMKFAIAVNASYFNTHRVVHEYCEKAYGTVFRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJI0</accession>
    <name>A0A010ZJI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442200.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020626_11_0_0"/>
    <dbReference type="OrthoDB" id="362657at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017895">
        <property type="entry name" value="HTH_IS408/IS1162_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50532">
        <property type="entry name" value="HTH_IS408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH IS408-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="131"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="516" mass="57905" checksum="5743FEFC2BCFE8FE" modified="2014-06-11" version="1">MTMYREILRLHFEGGLSQRDIAASCRCAHSTVKRILARAAELELDFNKIKELSDNSLARMIYPQAILPRIQKEPDYAYIHKELARSGVTLALLWNEYCAACQESGDIPYMYSQFSKNYKEYAAANSTSMHIAHKPAEVMEVDWAGTKILLRDAVAGKEIKASLFTACLPFSGYCYAEAFADEKLDSWLTAHIHAYAFFGGTAKILRPDNLKTGVVRSDKYDPEINSAYRELAEHYGAFVSPAKVRKPKDKPTVEGTVGMLTTHIIAAVRNVDYHSLKELNKDICLRFRQFNDRPFQKKEGSRSLLFSVQESRYLSPLPEFCYQIAHYKDAVVPANYHIQAEGGKYYSVPYECIRRKVTVRSTSSMIEVFCDGERVACHIRNRGAERYVTDSSHMPEAHRQLYAWNNDKFLEWGAEIGGGTLSVIQKILTRNGHSLPGYKFCMGLVSLSKNYAAQDIENACRALLALSSAPSLKSMKLALSAVTAKRNADDDSTQNDGPSVTGFRRGAGYYGGKSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJK3</accession>
    <name>A0A010ZJK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442271.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1039"/>
    <dbReference type="HOGENOM" id="CLU_1123368_0_0_0"/>
    <dbReference type="OrthoDB" id="1534863at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459067" evidence="2">
        <location>
            <begin position="27"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="252" mass="29018" checksum="7AABFCE5BBC812CE" modified="2014-06-11" version="1">MKKFTTFLIIIAALIFTLGDALPSDADTFGQVLQRWTKSRKHVDEDGANLEVRATYYSAEFIEALVQKEAKDNLWTQQETDDYKYKFLSSLKLDELIPIQIEFINNGPTMFLGPFDIMVKLRIAGKTYKPTDYDRRFNFKFQGKKEGLIFFPRFDEKTGKDLLKGVKNVSLEFVSAISPILEGKTISFIWDIDRDDPQALYRGKAADKLETERLLKRLEKLRKDKAEEEAKLASINGEISTIQARLDELAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJL3</accession>
    <name>A0A010ZJL3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="8" type="ORF">Cloev_0979</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710984.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1049"/>
    <dbReference type="HOGENOM" id="CLU_044142_4_1_0"/>
    <dbReference type="OrthoDB" id="1270636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="208" mass="22488" checksum="5F8B2CEFAD45839A" modified="2014-06-11" version="1">MSMGILGRKVGMTQVFDENGKAVPVTVIEAGPCTIVEIRTPEKNSYSAVQLGLGDVKPVKLTKPMKGYFEKQDVAPRRWLREFRVDSTADYQVGQEITVSLFQNGEVVDVIGVSKGKGTAGVMKRHGFGGTPASHGHSVTHRHPGSIGCSSFPGRVMKGRRMAGHMGSERVTTKNLKVFGIDEENNLILIEGPVPGARDSLVMIRKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJL9</accession>
    <name>A0A010ZJL9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">Cloev_0989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710998.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1059"/>
    <dbReference type="HOGENOM" id="CLU_095071_2_1_0"/>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="122" mass="13261" checksum="449F85B3D2C5AD79" modified="2014-06-11" version="1">MIQLRTVLNVADNSGAKKILCVQVKGGSFRKVGTVGDVIVGAVREAAPNGNIKKGDVVKAVIVRTKKEIRRKDGSYVRFDDNAAVVIDNNGDPKGTRIFGPVARELREKKYMRIVSLAPEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJN0</accession>
    <name>A0A010ZJN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">Cloev_1004</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1073"/>
    <dbReference type="HOGENOM" id="CLU_135723_6_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="41" mass="4913" checksum="44939010DCB7FD97" modified="2014-06-11" version="1">MKVRPSVKPICEYCRIIKRHGVVRVICSRNPRHKQRQGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJU9</accession>
    <name>A0A010ZJU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:ubiquinone oxidoreductase 24 kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1159"/>
    <dbReference type="HOGENOM" id="CLU_054362_2_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="160" mass="17882" checksum="E5716BDE15C22C8B" modified="2014-06-11" version="1">MTEKFDYALIDKILEEHESSGTAIIAILQDIQEHYRYLPREIFPYLSRKLRVPQARIYSVATFYENFSLNPKGKFVIKVCDGTACHVRKSIPILEQLRSELGLSDKKVTTDDLGFTVETVSCLGACGLAPVLTVNDKVYPAMTPDKASALLSALKEGLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKY1</accession>
    <name>A0A010ZKY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="8" type="ORF">Cloev_0011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034444894.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.14"/>
    <dbReference type="HOGENOM" id="CLU_024865_0_1_0"/>
    <dbReference type="OrthoDB" id="1009041at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="6">
        <location>
            <begin position="42"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="7">
        <location>
            <begin position="236"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="384"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="50"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG77917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="459" mass="49318" checksum="02B2AEC283C80A3E" modified="2014-06-11" version="1">MPAENLYYREEEGLVLPGSADRSETDMSYEAEPKSQAVFKKAIKVIAVGGGGGNALNHIISRGIEGVDMLAVNTDIRSLEMSLCDSKIILGEQVTKGLGAGAIPEIGARAALESLNDIRAYLKGTDMVYLAAGMGGGTGTGAIPIIARAAKEMGILTVAVVTKPFSFEGKRRRRYAEEGIERLFPEVDALIVVPNDRLLDISHRATPITESFSLADEILRQAVQGVTDLVTRPGLVNVDFADLKTVMKGAGRSVMGIGSASGEDCVIKAVKNALESPLMECSMCGAKGVLMNITYRGELPLYEISRAAELVEDVISDDSNFIWGCVSDPLIENDVEITVVAAGFDESPALDVIPQAAKEEKPAAAPEPALTKSVAVIYEEAEAAAPAKETAETAPEPRYERRRPIERDAHVPAWLLEEEPAEVKAADGRRPTNYTRPSAYEAYENPTFVRRGNSLKKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL11</accession>
    <name>A0A010ZL11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol dehydrogenase-like oxidoreductase</fullName>
            <ecNumber evidence="8">1.1.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0047</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.6" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441229.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.56"/>
    <dbReference type="HOGENOM" id="CLU_044754_1_0_0"/>
    <dbReference type="OrthoDB" id="717704at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008888">
        <property type="term" value="F:glycerol dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe-ADH" evidence="7">
        <location>
            <begin position="8"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="90"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="112"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG77952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="361" mass="38097" checksum="E8FC8C0283206F0C" modified="2014-06-11" version="1">MSNIIIAPGKYVQGKGELSKLGGYVEKLGSKPFILVSPSGMKRVKEPITKSFGATTPLFEEFCGECSKKEINRLIGKMGDCDVVIGVGGGKILDTVKAVAHYAKKPVVIVPTIASTDAPCSALSVIYSDEGVFEEYLFLPANPNLVLVDTDVVSAAPARLLVSGMGDALATYFEARAVKASDSGTCAGGKATNAAISLAKLCYDTLIENGLRAKLAVERHVCTRAVENVIEANTLLSGIGFESGGLAAAHAVHNGLTVLEASHQFYHGEKVAFGTLVQLVLEDAPTKEIEEVIDFCLDVDLPVCLEDIGITDPKPEEIMAAAEATCAPAETIHNMPFEVTPDKVYAAIMGADALGRFYKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL26</accession>
    <name>A0A010ZL26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn-dependent alcohol dehydrogenase, class III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441241.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.76"/>
    <dbReference type="HOGENOM" id="CLU_026673_14_0_0"/>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="12"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG77967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="372" mass="39623" checksum="E9F5CC199E05A23D" modified="2014-06-11" version="1">MKIKAAVMTAVGKPLEIREVELDKPKSNEVLVKILATAICHSDLNTLNDETTPIPQVLGHEGAGIVVETGESVKTCKKGDFVTLSWVPYCGTCAFCRAGKVNLCESAFGPMFGGTLMDGTSRLHLDGKPAYHMSLLSTFAEYTVVPEMSCIPMPEGMPAAPACMIGCGVATGYGAAVCAAQVRPASSVAVFGIGGVGINAIQGSRVCGASQIIACDIKDDNLELSKKYGATHTINTKNVADVPQAIRDLTEGLGVEYAIDCTGNTKVGAMAFMSTRKGATTVVIGAYPADGKLELPAGGFHRYGRILRGSFYGDVNPFQDFPRIGQLYLDGKYDLDSLLIKKIKLEDINEAFDAFHDPNAKNMGRYVIEFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLD4</accession>
    <name>A0A010ZLD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative xylanase/chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709288.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.199"/>
    <dbReference type="HOGENOM" id="CLU_084199_0_0_0"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="292" mass="32179" checksum="2CC1E8FD0EDE4FBD" modified="2014-06-11" version="1">MTRLAVKVDVDTLRGYLEGVPRMLALFKKTGIRASIFFSFGPDNSGKAIRRIFRPGFISKMMRTKAPSTYGLKTLMYGTLLPAPLIVPADPGIVRRASEEGHEVGVHAWDHVYVQDCLGKISKEEYLALYKRAEALYREICGRGPAEIAAPGWQVSHAVLEAEQELGLAYASDVRGYAPFMPVFEGVEYGVPQIPTTLPTMDEIYGLPGINDVTIPKAWLDGMDKDWNVLTVHAEMEGISKLTVFENFLNMAKALGVEFRTLGEYAREAPLPRGEIMIGTLTGRAGTLAVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLE3</accession>
    <name>A0A010ZLE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP-type C4-dicarboxylate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484785.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_1_2_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457979" evidence="2">
        <location>
            <begin position="32"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="345" mass="38657" checksum="50A0CF4F415D22E1" modified="2014-06-11" version="1">MLHRGFFKFLASPFALAVLVLLLCGARSAQAAPLVLKFAGQNPPDHFATVSMRDIAKEVEKNTNGRIQIKVFPANQLGDYSLVYEELVRGTIEMAAISFPSQFDSRMDLIYVHGYTGSYAQVAKVYAPNGWFFKKMDEFNKALGVKLLGMYLEGMVGMGTVKEMRDPLNPKVDHGVLLRIPNMDVFKTALEGSKYRTISIPFADVYQSMQTGVCDGDTGYSIVAAYTALGDVIKHWYNLNKNTECLGIMISAKVWDKLSNDDKKVLQAAVNKQTALSIKNAEANDKKFLELMRKKGIKVHTYTTEQLRPLMDAFAATWGQLDQSKGKELMDEFRKEMKRISDSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLM6</accession>
    <name>A0A010ZLM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydrophobe/amphiphile efflux-1 (HAE1) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441435.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.287"/>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_0"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="471"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="866"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="891"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="919"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="968"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1001"/>
            <end position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1041" mass="111714" checksum="3850BCDA4B23AAF7" modified="2014-06-11" version="1">MFAKFFIERPRFAMVICILLGLAGTIAAFSLPVAQYPDVTPPQIRVNTTYRGADASTIANTVGVPLEEMVNGVEGMIYMNSTSSNNGQYTLYVTFATGTDPDMALVRVQNRVSQVTPQLPSEVIDEGITVVTAFSDTLGLLALSSPNGTYSELELNNYAHSNIKNQMKRVYGMGEVVVFGSKYSIRVWLDPARIAALGLSTGDVAAAIQSQNKQASIGSVGAAPGNSDSPLVYSLQAKGRLSDVRDFENIIVRTTAQGGLVKLRDVARIELGAESYNMNSSENGGAAAAMMLSQAAGSNALDVMAGVKKTMAKISATLPKDMELRLPYDSTLYVQATIKEILTTLVLTFILVVLVCYLFLQDWRVTLVPVAAIPISLLATFIGLAAMGYSINILSLFGLVLVIGTVVDNAIVVVERVLFIMDRDGCTPREATLQAMDDVTGPMAATTLVFLAIFVPVGFMSGITGQIYKQFAVTISFAVVFSLVVALTLSPAMCAYLLRQVKPARRGPLKWFNNALAGATRGYVAGSVWLAGRVTVSLCALAAVIAACWAITVTTPTSFIPDEDQGAVFATIQLPEGATMPRTQKISRAMAKEALALPGVRDVMNIEGRNLLGGDGENVASLILSLKPWDQRKTKDTQLGYLVSRTNEIAAKYRGAKISVFTPPAISGIGMASGLDMRLQSAKDNDPAQLAEVMEKLLAEINKAPEFLYAFSTYTANTPHLYLDIDREKAEMMDVPVSSIFSTLQTYFGSAYINDVNIGTQVNKVMLQSDWGYRSNIDSIGGIFVENASGGQVPVRSLTTVRKTLAPRTIDRYNLYPSAGITIVMKPGYSTGQGIARVAGLAKSLPEGYTYEWSGMTYQEQDSRGGILLVLIIALVFAYLFLVAQYESWTVPVPVMLSLPVAMFGALGGLRMMGLSLSVYAQLGILLLIGLAAKNAILIVEFAKEQREEHRLPLIQAAATAASERFRAVLMTAFTCVLGVLPMLFASGAGAASRKAVGTTMFFGMSAASILGIFVIPALYVIFQGAREKIKGRMGSVKREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLV0</accession>
    <name>A0A010ZLV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0327</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441511.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.357"/>
    <dbReference type="HOGENOM" id="CLU_049002_1_0_0"/>
    <dbReference type="OrthoDB" id="1559099at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="297" mass="31306" checksum="5E5FD1D3B7AFD3A3" modified="2014-06-11" version="1">MIEYEFAYFSHCFITLFKDIAPFWGLGILMGSSISVFAKERIHGLLGAMRGARLGAAGVVPASLLGIASPLCMYGTIPIAASLSEKGMNDDWLAAFMMSSILLNPQLMIYSAALGMKALAVRTLSSFICGAAAGLCVRYLFRGGKFFNFSGFAEGENRDTDPDMAMRLLKNILRNIRATGPYFFAGVVLAAIFMCFVPQTAVAGLFGGDGGWGVIAAATAGVPLYVCGGGTVPLLAEWMQSGMGMGAAAAFMITGPATKVTNLGALKIVLGIKNFALYLLFAMIFAAVTGLLTDLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLW7</accession>
    <name>A0A010ZLW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative branched-chain amino acid permease (Azaleucine resistance)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0342</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441528.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.373"/>
    <dbReference type="HOGENOM" id="CLU_065777_3_2_0"/>
    <dbReference type="OrthoDB" id="1866750at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="240" mass="25331" checksum="BA402F4FF13D7FF9" modified="2014-06-11" version="1">MAKRDIYYFSKGMRDAIPILLGYIAVSFTLGIGAKNAGLSPFQALLSAVTQNASAGQFAGYSLIAAGAGYLEVVIMIIVANARYLLMSCAMSQKISPETPLRHRMLLAVDITDEIFGLSVAQPKRLNPFYTYGMVAAAAPGWALGTFLGVVVGNILPQNIVTALSVGLFGMFIAVIVPPARKNTVIALLIAVSMAASFALSRLSAVELSAGVRTIILTVAISGTAAFLFPLREERRTNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMW1</accession>
    <name>A0A010ZMW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AcnX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441959.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.758"/>
    <dbReference type="HOGENOM" id="CLU_018825_1_0_0"/>
    <dbReference type="OrthoDB" id="1159371at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007506">
        <property type="entry name" value="AcnX_catalytic_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04412">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcnX" evidence="1">
        <location>
            <begin position="1"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="405" mass="44763" checksum="DD1A8E202ABFD5ED" modified="2014-06-11" version="1">MYLTDEEKRILDGAEGAGKQKAMEMLYALGLTFDAEKLIPVKRAHVALSGQEGDTYWCELLVNGGATCVVPPTTNPYWDTAYLTKFFDVTKEELDLADRTGDAYRRIGAKLTYHCAPGVCSNVPFFGEHVAFSESSATPYVNGALGARSNRESSVSALAAAVIGKTPYYGYHLDENRYGDFLVDVDADLESCYDWGILGHCLGKIAGYRIPVLRFKKDIRPTQEDFLYFGAEAATSGAVAMYHMVGITPEAPTIEAAFGNRKIPAAECVLTNKDLKEREDMLTPATGKINLVMLGCPHYTYNQLLDVEKLLDGRHICNDTAFWILAESGAVELAERSHLRQRLELLGVRMVGDTCIDEPCWKSFEGALGVTDSPKCAYYRERRGQPFAIRRLSQCIDAAVKGRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMX1</accession>
    <name>A0A010ZMX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ORF">Cloev_0720</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.769"/>
    <dbReference type="HOGENOM" id="CLU_014271_4_2_0"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXG78592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="559" mass="59405" checksum="00EA5703055F31D4" modified="2014-06-11" version="1">MKYKSTRQLENMNFKEARALYKSMGCSDADLKGPVIGIANSWNELVTGHFNLRQVAEFVKKGIYRAGGAAVEFGMIGACDGLASGHGGMKYILPSRELIASDLESMARAHNLDGLVMLGSCDKIVPGMLMGAARLDIPAIMAVGGPMLGGVEFDGRKSDSTSLSEAVGMFEAGTIGEDELNRLEETSCPSCGSCSFYGTANSMGALAEAMGMSLPGSALIPAVYAERLRSSEEAGRRIVELVNKNITARSVITEASLENAAVVMLATGASTNCVMHLCAIAYEAGLDPKKIFAAIDALSERVPLVAKVNPAAQYDMEAFYRAGGVRQVMREVRSLLHLDAVTVNGRALGENIDDFRNPYGADLNVIRSVDEPFSREKGLCLLRGNLAPEGAVAKPAAMDPSMFCFTGPARVFDSEEEANRAILAKEIAPGSVVVVRYEGPKGGPGMREMFHAMKFLYGMGLAKKVALITDGRFSGTNNGCYVGHISPEAAEGGPLAALRDGDMITIDINKKEVSADLSGEEIASRLKDWRAPVPDAPDGWLKIYAKLAASATDGAMMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN02</accession>
    <name>A0A010ZN02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710636.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.801"/>
    <dbReference type="HOGENOM" id="CLU_120911_0_0_0"/>
    <dbReference type="OrthoDB" id="1757687at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="2">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="155" mass="16423" checksum="8A94BDDF75EDE2BD" modified="2014-06-11" version="1">MAEKRPGIIDLFVSGARRGFNISMTGMLPNVVMAFVIIRFLDMSGFLPLISKAAAPVMALFGLPGDAMIVLVTGFMSIGGGCGAAAALAAAGKLSMDNMTQLLPCVLLSGAMVQYMGRCLGTADARKKYWVLHCLISICNGLIALWIMKFVILAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN63</accession>
    <name>A0A010ZN63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA epimerase</fullName>
            <ecNumber evidence="4">5.1.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.1" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710724.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.851"/>
    <dbReference type="HOGENOM" id="CLU_046006_5_2_0"/>
    <dbReference type="OrthoDB" id="1335734at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="3">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="134" mass="14617" checksum="55FB6876C677180F" modified="2014-06-11" version="1">MEIKNVDHIGVAVKSIDEALKFWEDTLGVKCHGIEEVAEQRVKTAFLPIDDTEFELLEGTTEDSPVSKFIEKNGQGIQHVAVRVADIEAALAELKEKGVRLIDEKPRIGAGGAKIAFVHPKASGGVLLELCQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN87</accession>
    <name>A0A010ZN87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycerol dehydratase, cobalamin-independent, large subunit</fullName>
            <ecNumber evidence="6">4.2.1.30</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.30" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442049.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.872"/>
    <dbReference type="HOGENOM" id="CLU_009096_0_1_0"/>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046405">
        <property type="term" value="F:glycerol dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010098">
        <property type="entry name" value="PFL2/GDeHydtase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01774">
        <property type="entry name" value="PFL2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0556">Organic radical</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PFL" evidence="5">
        <location>
            <begin position="8"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="4">
        <location>
            <begin position="668"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="658"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2">
        <location>
            <position position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="790" mass="86851" checksum="CEA93FA977063C39" modified="2014-06-11" version="1">MVREESLKRINGMKERMITNCPTELLPERALLVTEAYKRYASEPPVLKRAYALKHILENMTLFIDDEELFVGHNSPRPRSPIACPELGARWILSDLDNFATRPADAIGVTEENKRILRECLEGWQDASLDSVTAALVPAEAKEAIAEAMITVGAQGTAHGNIAVNNKKLLEKGLRGIIYEIEAKLASFKPQCAADGNKVAFWRAAKISCEAVIAFARRYSGEALKRAAECPDPARREELYRIAETLKRVPEFPASNFREALQSVWLIYVATQIEADPHAMLLGRFDQYMYPYYKKDIADGRLTDEEAVELLAHIWIKCTAIIKLMDSVTTRTFAGFPLFQNITLGGQGPRGEDACNELTTLIMEAAAIARVPQPSLSFRYHNKVDPDALLKACETVKLGLGYPAVMNDNCIIPKHLIRGATLEEARGYCMNCVESDIEGACDSRSNGGYVNLPKAFLLALNDGADPATGRQVGPHTGKLAGFANFGGLMRAFESQVAYFVELIVRSYDLIDGAHAVHAPEPFTSALLDDCVETGLTRQEGGVRYNFSGIFGVGLASTADAMAAVRRVVFDDKSATPEELLSAIKNDFAGAAKLKKLCEEAPKFGNDDDYADLIARETSHIFCKEVVQYPCMRGGFYIPELHSVSTHVYFGELTGATPDGRPAGTPFSDGASPVGGRDRNGPTAAVRSMSKLDHMEVLQGVLYNQKFSPSVLSAPNSAALLADYVRAWCDLGGHHIQFNIVSSDDLKEAQRRPDDYRDLIVRVAGYSAYFAELNANTQNEIIARTEYEEMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNA0</accession>
    <name>A0A010ZNA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.883"/>
    <dbReference type="HOGENOM" id="CLU_122785_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="22"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="146" mass="15855" checksum="C1089BF8C013869F" modified="2014-06-11" version="1">MQNKKGRIIAVCSAPQKGMIKHEIGEGRLIEGIGLEGDAHAGFMHRQVSLISMEDIRTMMAKLPNLVPGSFAENLTTEGFDLGQLKIGDMLKVGETLLEVSQIGKECHSHCEVFKQTGECIMPKKGIFTKVIKGGKVKAGDTIEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNJ8</accession>
    <name>A0A010ZNJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442193.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062999_7_0_0"/>
    <dbReference type="OrthoDB" id="1792718at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028350">
        <property type="entry name" value="DNAC/ATP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003073">
        <property type="entry name" value="DNAC_TnpB_IstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="9"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="248" mass="28372" checksum="070F37C17E7B8409" modified="2014-06-11" version="1">MISQITLNQLRDMHLTSLAADIRERSESKGFTELTFDQQIEVLIDREWHRRKDNTACVHIREASFCYPSASALEIDYSEDRGLEKRKINELVECGYLLHGRNIIIMGATGVGKTYLACALGTAACRNRYTCKYIRMPNLLDELALAREDGSFSKTIQRLSKVSLLILDEWLLNRMSSNNITDIFELFEYRYTMHKSTIFCTQIDVSEWMAALGNGLISESLLDRIIHNSESMLIAGDSMRKRLASVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNY6</accession>
    <name>A0A010ZNY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711213.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_4_0"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="59" mass="6271" checksum="96C0BA96AFFE9028" modified="2014-06-11" version="1">MGIKVNLDDCIGCGVCFELCPQNFKLDEDEGKCMVISNEVNSSAKEAADSCPVSAITID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7D5</accession>
    <name>A0A011A7D5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent aldehyde dehydrogenase</fullName>
            <ecNumber evidence="5">1.2.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.99.3" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441239.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.75"/>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_0"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="27"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="496" mass="54387" checksum="0790ADD9737761FA" modified="2014-06-11" version="1">MSEFAPKREWAKEWLKDVKSLYIGGQWVKGHGNTFQSSNPATGEVNGTLAAASAEDVDAAARAARKAFEGDWTKSISNKERGIIMRKLAQLVRDHVSELATIETMDNGKLFSEACEDAVNVADFFDYYAGWTDKIYGEVNPVSNGYFSYTRREPVGVCAQIIPWNYPLDMAGYKLGPALAAGNTLIMKPSGITSFSLVRLYEIFDEAGVLPPGVMNLIVGRGAVGSLLTSHSDIDKAAFTGSTEVGRSLVRDSANSNLKTLSLELGGKSANIIFADAPDMAWAIERSFVAMFSGKGEKCSEPTRLFVERPVYKQVLEGLAEQYKKWKVGDPFNPENNQGAQVSEEHFNSIMKYIEIGKKEGGRVICGGGRNVEGANAKGFFIDPTIFADCTNEMRIAREEIFGPVLTVIPFDTEDEAVRMANDSTYGLAAGFWTNDVKRTQRVANALQAGQIFINKYGCYDPASPFGGYKESGWGRECGARSLELYTKAKAIWYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7F5</accession>
    <name>A0A011A7F5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="4">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441268.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.99"/>
    <dbReference type="HOGENOM" id="CLU_668512_0_0_0"/>
    <dbReference type="OrthoDB" id="1726104at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016994">
        <property type="term" value="F:precorrin-6A reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003723">
        <property type="entry name" value="Precorrin-6x_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36925">
        <property type="entry name" value="PTHR36925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02571">
        <property type="entry name" value="CbiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00715">
        <property type="entry name" value="precor6x_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51014">
        <property type="entry name" value="COBK_CBIJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG77986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="411" mass="44073" checksum="7206D2D9AF5B16A2" modified="2014-06-11" version="1">MKRRILLFGGTTEGRELTRFGLPLIYSVATAYGAELVRGAENTEIAVGRMDAAEMEKFIRESGIACVIDATHPYAREARENIRAACAASGTPLMRVQRRESAADEEVIRVKSAEEAARRLEETTGNALLTTGSKELEAFACVSARSRLFARVLPDPEVIKKCAACGFDSGHIIAMQGPFSLLMNEEMIRLTGARWLVTKDGGAAGGIEEKLEAARNCKARVIMIERPREEEEGHSCAEALLWARRILGLSRPPLFPLLTDMEGRRAVIAGGGGVAARRAATLVKCGAAVTVVSPAFAPEFRELKCSLLKKEWEPEDLEGAALAVAATDDGTVNAAVAAEAKARGIPVSVADNAAECSFFFPSLVTSGEVSASVSAGALSPALTRRLAERLRSVWGEWVKEERAALEDKNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7J4</accession>
    <name>A0A011A7J4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709212.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.140"/>
    <dbReference type="HOGENOM" id="CLU_025763_1_2_0"/>
    <dbReference type="OrthoDB" id="1184827at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="188"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="425" mass="46463" checksum="D811F94FC267D1F7" modified="2014-06-11" version="1">MAVQKRTSTNVLLHTALQNFYDAAEEMGLEDGLVEVLSRPERAICVSVPVQMDDGSVRVFNGYRVQHSTVCGPAKGGLRFHPDVNLEECEALASLMTWKCSLAGIPYGGGKGGISVDPFELSPREREMMTRTFAARIAPFIGDWTDVPAPDVNTGGPEMVWIMDTVSKLRGHLEPGVVTGKPIAYWGSKGRTAATGLGVSTCVLELLKTQHIDPKDATIIVQGFGNVGTYNALFLQEAGAKIVGISDITGGYYNPNGIDIKAAKAYVEKHPKRILDGYTEPGLVKMSGEDILEQECLVLSPCALEGVISEKNAGKLKCKYIVEGANGPTRPEGDKILDERGIIVVPDFLANSGGVIGSYFEWVQDLAGFFWTEEEYNNRLVPIMKDNFKRVWDYAQEHNVKMRRAAFLVAIKRVADGLKIKGFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7M6</accession>
    <name>A0A011A7M6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multidrug export protein MepA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0165</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441345.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.178"/>
    <dbReference type="HOGENOM" id="CLU_012893_0_1_0"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="472" mass="50663" checksum="910242AE0C1D5111" modified="2014-06-11" version="1">MLGHRSSAALGKEEQRRRMLSEPVGRLILSLGGPTTVIMAVTTIYLISNVFFISKLGTSANAAASVVFAIFAFFNAVGYTFGRGAESKIEISLSAGDDTEASRFASTSFYSVILIGTLTALLGIKYVEGLMRLLGATDSILPYAVDYSRHVLLSAPFACSAFVMNNILRAEGKAVYSMRGLLGGSLLNIVLTPVLIFPLKMGIAGAGAATLVSQCVSFVILYEYFLRGKSITRLTLAGVSRDPREYYDIFRIGSPSMTRQGFSSLSTAALNYAAGAYGDAAIAAMSVVSRVVMFLFAIVTGITQGFLPVAAYNYGAKQYARIRQGFWFTVRAGLLCMSVISLLTYIFAREIVTVFSYGDSAIIGVGTFALRCQAAVFILQPLFIVTEMMMQELGFAARASVLASLRQGIFFLPMLAVLPSFMGLDGVAVSQAAANVMTLFATLPFVYSFMKLLDTKEKAMPDSTETTASAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7Q9</accession>
    <name>A0A011A7Q9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441375.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_672554_0_0_0"/>
    <dbReference type="OrthoDB" id="1249079at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="425" mass="48026" checksum="81F66678B4669707" modified="2014-06-11" version="1">MENEDKMSGENIKCPDMVPEEQKGMTEEEREWSVKSPPRPRVPRYVFVTIALILLIAFGGGSWWYYRKNVLPEKYYLRATALMKEKEYARAEELYRRIMKIRPERRDVLYNIAYCKEETGDTAEAIRYYEEHLKTAKNDAKAMTRLGWLYMKGGEYERALRWLKEAASRDKKNDELWRLTAGAAVKAGDGEEAAKAWAHIATLYKEPDKIMECGKELLALKDYRRAIDVYVLAAKAAPGDNRPLHGMNAAKAMLGLPTEAKFVILPGKSLGLIKLDASKEEVKEEMGGKSPDAKIFGHVGGKSMMADHPVEIWLYNKDDPQRELRVIFIAGKVNEIETASPLYRTEEGLGLSNFLLAKNADKLKWRKEARNSALLCLAKGGGLTFFASGLNENGTEAADKRLRVHHGEVSIDNVDGFSLMRLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7W9</accession>
    <name>A0A011A7W9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lauroyl/myristoyl acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0247</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049421_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="316" mass="36479" checksum="47A470F1B3FF2501" modified="2014-06-11" version="1">MVPIISGPRYDGRPHYGRLKHLKEETRKKITDHQVRAFMAFARSIRPGWRANLLAGAFIPLLRLIGVRKDVARRNIMLCFPEKEKAEREKILAESYESMIWTGVEMLAWQHDPSLIDRMVLEVRGIEHVEKALKEGRGAVLFSAHLGSWELGAAWCSRHFPFYGLVRHSDSPFQRRLIETLRENSGLRTISKDSSMKHVATLLKDNTMIGFLADQHWGDDGMSVPFFGQNTSTASGPAAFSMLTGAPMIPVAFTRIEPFKFYLSFGKPIEHPQNMKRGEAVRSLTIRMNEEYERMIRENPGQWLWQHRRFREMITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A827</accession>
    <name>A0A011A827_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441466.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.321"/>
    <dbReference type="HOGENOM" id="CLU_038297_2_0_0"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459353" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="88"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="362" mass="39546" checksum="B47A218B85AC76A2" modified="2014-06-11" version="1">MNMMKRKSVLLLTTAIIVTIFAAAAAAAPLKSRPLMIEEQGSFAAGGSIVSSPGKFDPYKWNGDGQTLHGDHASVFYQIPVKARKLPLVFLHGAGQSGRTWETTPDGREGFQDIFLRRGFGIYLLDQPRRGSAGRSTVPMEVKAIPDEQLLFGIFRLGTWPNFYPNVQFSRNPRALEQFFRQATPNTGPYDAGVVSDAVSAVFDRIGEGVLVTHSQGGGPGWYSVMKNNKIRAVAAYEPGSDFIFPQGEEPAPMPSSAGTLKAVGVPLADFMKLTKIPIIVYYGDNIPGEPTDNPGQDNWRVRLAMARLWAKAVNEKGGDVTLVHLPEIGIRGNTHFPFSDLNNIEIADLLSKFLKEKGLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A869</accession>
    <name>A0A011A869_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441508.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.356"/>
    <dbReference type="HOGENOM" id="CLU_028523_1_0_0"/>
    <dbReference type="OrthoDB" id="1547060at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="271" mass="28691" checksum="8AD54E8D420C14A3" modified="2014-06-11" version="1">MRTLYLDCGMGAAGDMLTAALLELHPDPAAFLERMNALAIPGVEVSAAPCVKCGITGTRVTVTVNGEEEESAEGETCRDCREHHQAHAHEHAAHHHHEKEHSHAGMHEIEHLISHLDLPEKVRSDVIAVYALVAGAESKVHGRPVSEVHFHEVGAMDAVADITAVCLLLHELAPERIIASPVHVGSGHVRCAHGVLPVPAPAAAEILRGVPIYGGAVRGELCTPTGAALLKHFAADFAPLPVIKISGIGYGMGKKDFAWANCVRAMIGDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A880</accession>
    <name>A0A011A880_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-dependent hydrolase</fullName>
            <ecNumber evidence="1">3.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.9" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709011.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_3_0_0"/>
    <dbReference type="OrthoDB" id="831439at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="220" mass="24584" checksum="C37AE2F75163F7CD" modified="2014-06-11" version="1">MSKILDLSLELHEGMPTYPSPWHPVVDVKQMGRIDMEARRSYAVTLGSHTGTHMDSPAHMVKNGITIDMIPLETIVGTAKVIDFSNKSRGDKITLEEIKNCGTEIEKGDRLLIKTGWYKEWGSNAYYDRWPWITAEAARYIVDQGAIFVALDIPSPDDPLSDTGYGKHSPIHDIFLQNGVILVEYLNNTLDIDKDVIKLTALPLKVKGCDGFPARVIAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8G9</accession>
    <name>A0A011A8G9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidase, deaminating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441620.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_1_0"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="9"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="384" mass="41995" checksum="8CC539282FF400C9" modified="2014-06-11" version="1">MSDFPKTADVVVIGGGVVGTATAYYLAKSGRKNVHLVEKNTICSGSTGRCGAGIRAQWGLELNCLMALRCLETFEQLDEELGLPTGLNQGGYLLVAYQEHEWEQFKKNVVLQHKLGINSEIFEDKKRAQEICPGVAVDDALGFTFYQRDGHADPFLTTFAFQEAAKRCGAKFHKFTEVTGIDMKDGKITGVKTNRGTIETECVVNCAGSWAAEIGNMVGLNIPVRPERHEIIITEPVDPGVCPPMLMSFSGNYYIQQRPHGSIIAGESPVHDQPGIDYTSTVTSPASIAKTILKLLPRAKNIRVVRQWAGRYEMTPDAAPVLGKTEIPGFWLATGFSGHGFMLGPVAGQIMTALLNGEKPPFDPTIMDYKRFERGEMIVEPNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8I3</accession>
    <name>A0A011A8I3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tripartite ATP-independent periplasmic transporter solute receptor, DctP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709127.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.466"/>
    <dbReference type="HOGENOM" id="CLU_036176_1_3_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459456" evidence="2">
        <location>
            <begin position="24"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="329" mass="36307" checksum="A1B658F072CF0A5E" modified="2014-06-11" version="1">MKKLLAVLMVASLVFCFAGAASAAEPIKLKLGINDPDSSNYYKGAKAIADEVRKATNGRVEIAVFPSGQLGNEREMVEAAMMGTLDMWSAASSVLANFIPQMKILDIAFLWDNDRQANACVDGEMGKLIAAECEKKLNIKLLGWMESGFRDVFATRPVKEVKDFKGLKIRTMQNEYHMAAFNSFGAIATPMAYNDVLPALQQGTIDAAENAISNCIASGYYEVTRHVTRSHHAFVYIPVGVSMAAWNKIPADLREPFAKAVAKGCKIQRKYLIEANNDATKKLKELGVNIYDIDRAQLQKLYAPKKAEALKKMDPKYVALVEKAIKENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8I6</accession>
    <name>A0A011A8I6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441637.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.471"/>
    <dbReference type="HOGENOM" id="CLU_024540_4_2_0"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="180"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="187"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="483" mass="52225" checksum="E00C34194D62428D" modified="2014-06-11" version="1">MMKKADIGLIGLAVMGENLVMNMESRGFTVAVYNRTAERVDSFVKRRAGGKNIVGTKSLAELVSTLSLPRKIMLMVKAGPAVDSLLESLLPLLEPGDIIIDGGNSRYTDTIRRCAGVESNGLLYIGMGVSGGEEGALKGPALMPGGSPAAWPFVRPIFQAIAAKAGGEACCEWVGENGAGHFVKMVHNGIEYGDMQLICEAYSLLRVLLGMNAEEAADVFESWNKTELDSYLIEITKNILRYKDNDGAPLVGRILDAAGQKGTGKWTAVSALDEGVPLTLIGEAVFARSLSAMKDERVKASEAFAREKTPFDGCRESFIEDIRRALLASKIVSYAQGYMLMRAAAKSYGWNLNYGGIAQIWSGGCIIRSVFLGKIKEAFEAEPELANLLFAPYFRDKVKDLVPSWRRTAAAGVLHGVPLPAFTSALSWFDGYTSAALPANLLQAQRDYFGAHTYERTDRPRGEFFHTDWTGEGGATAAGNYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8P0</accession>
    <name>A0A011A8P0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441753.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_770986_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="359" mass="38135" checksum="B3B172BA0615724F" modified="2014-06-11" version="1">MAVYFAPRNSNRITINDILGMVGGRFLDSMMARDEAARQYKYRSRLDAEAAARSEAEKRGYIDMMRSGVDNNPNQQAGAADFLGGAVGAGANLQHLQNYWLPQMLTVDQGNQKTVAPAWSNGAVGDGRSYDMGVDPAKAQEMSDKLKMYNAGLAWDREQGLWERDYKNRALAQEASIRREGQRRQQPAQLMPDGKGGMVWVDPVSRSIVPAEGITPGSGGSMLESLFKASGAYKNFYGNNGGSSGQGVVDGGDGAAQPQMDPIKFLQVMGLLGNDGGVPFSDYKPLYESIGDGGLNAYSSALGGVGGPAAAGGAARSPQTAGSGGKRISMADIINEANIQNRLPADLVREAQESGFTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8U1</accession>
    <name>A0A011A8U1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding transcriptional activator of the SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441812.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_1_2_0"/>
    <dbReference type="OrthoDB" id="1405820at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="232"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="971" mass="111602" checksum="A195223BED7AC516" modified="2014-06-11" version="1">MKISLNLSGAPSVLKDGKRVVFPTKKAEAIFYYVALVGQVSKSALELIFWPELDQLGANKNLRNSIYYITKIFGRDVFKKDRGVLEFSDGVELELLTEPLGGEFMEGFYLKDCPDFNSFAEEYNKRQSMRLYNSAKGVFLDELAKGKLTGQQALGRIAALSKMDPYDEEVVLAVMERCFTEKRLDDLILLYRDFEKRLISDLMVEPRKELQNLYRTALMQKKAARGNTEPYFYGRREELKKIDGAHRNFSAGEPYANLIIAGGIGSGKTCLLNHYLRNNDVAGTTVISLVCYEAEAKIEYRILSLLTGKMLKALKIGTAALPESYRRIMLYFFPFMFNGGAQGEAPRIDKASLPLFELEDLFSELFGYLAARGKFVVVIDDIRFCDRRSLDFIQRVAVYKYCRRVLFIFSCHESWLGEYIKTFDKSVLQNIDIIELRNFERGEVESIAARSLKEPGAELVDSIYRESGGNPLYLFEIINNLKENKNVKSYKFFYLLENRLKTLSDHEQAVLYISSTFFSGIMPEAVASIVGVDYIKALELYEPLVRNGFLKEEIKDGRLTLLFAHEQFRSYIYQSQPLIKRKTIHMKIAEYLAAYGEKNGCLKDHIDNIIYHYGNAGQTTKYLHYKLMKAASIVSIDNDFPEFLTSFTQSFIDELEDEFSRQPVPVDLQYEFTLLKASFAIKACDYGRGLEYIEKLLEFDTDTRRLLKARKQLIYYGIQTRDYTMIKENAVEALRILKKIPDDVERADILKSYALAEINCRRYKNAKSMLLKSLSLLCSAPLNENVISIRACVFNYLAYEYKYAGEYERCIPLYRKAIELCLSANITNGLPLFYMNLGQALVKTGRLKEAKEYFLKFEILREQIYSALSTTIVKAYLAFIYSFEKNYRLSAKYLAEGFECSRLIKNPYEYAYLYKICALLKKNAAADGEAAAVIDSVLPESYEYYRERAAENFITIGLERELAELELPPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8U6</accession>
    <name>A0A011A8U6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">Cloev_0561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.601"/>
    <dbReference type="HOGENOM" id="CLU_035188_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="308"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="358" mass="39697" checksum="ACDB1EA992169BA2" modified="2014-06-11" version="1">MENNKALIAMSGGVDSSVAAFLTKEAGFDCTGATMKLFSNEDIGIEGESRCCSLDDVEDARSVANRLGIPFFVFNFSDNFRREVIERFITAYKNGETPNPCIDCNRFLKFEKFFLRARELDIGHIVTGHYAVICYDGAARRWGLKKGADESKDQSYVLYSLTQEQLAHTLLPLGGMTKAEVRAVAEANGFINAKKRESQDICFVPDGDYASFIERYTGEPNLAGQFVDKEGRALGEHRGFVRYTIGQRRGLGLSLREPLYVCAKCAARNTVVLGKESELFSKSLTATGINLIACDRLTAPLRIRAKVRYKQREQWATAEQTGDDRLRIEFDEPQRAVTPGQAVVMYDGDAVVGGGTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A923</accession>
    <name>A0A011A923_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2914317_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="61" mass="6551" checksum="EFFA9BC0FC88AB80" modified="2014-06-11" version="1">MTTPQHRMAQPLSTLEACKGCIHDCKISSLNGAALVCCPKYRAVKRRRTSQAADKAPHGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9B7</accession>
    <name>A0A011A9B7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710633.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.800"/>
    <dbReference type="HOGENOM" id="CLU_019748_3_0_0"/>
    <dbReference type="OrthoDB" id="319106at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="2">
        <location>
            <begin position="324"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="482" mass="52852" checksum="DF0AFC261C38619B" modified="2014-06-11" version="1">MDSLSNFKDRIRKKSLLSKIMSPEEASQYIQPNMLIGCSGFTPVGYPKVIPAALAKRAETEGPVPLTLWCGASSGREIDEELASSGCIKRRYPYQSNKVMRSMINEGKIEYSDIHLSMGGQNLRYGFYGKMDVALIEAAAITENGGIVPSTAVGDAAAYVRCANKVIIEINLTQPAELEGMHDIFIPQDPPYRKPLPLRSVRDRIGVPFIECGAGKILGIVPSSVPDCGVLYDKRCDPVSEKIAANVLNLLDLENKRPIIPINQLPLQFGVGRVANIVLSELAKTVRGDIKIYSEVLQDAVLDLIDAGKLAFASGTSLTMTKGGLQRLFQHLEDYKEKILLRSEEISNSPEIIRRLGVIAVNTALEADIFGNVNSSHNGYDIVNGIGGSGDFARNAYLTIFVCPSLYKTDGSSNIVFNCSHVDHTEHDVDVIITEYGVADLRGLTRTERAKEIIGKCAHPSHRCGLYKRLRSMRHCRRETGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9F5</accession>
    <name>A0A011A9F5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710688.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2630311_0_0_0"/>
    <dbReference type="OrthoDB" id="2055702at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="74" mass="8707" checksum="659FEEED8BBE3810" modified="2014-06-11" version="1">MSRAFVKEDDGERGNAVADIQFREEKVEWLRIQEKKLDTLLNDPKSKKIKPETLARWIKETEADITKTKKELGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9I1</accession>
    <name>A0A011A9I1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0814</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442041.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.866"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="345" mass="37835" checksum="2BF44EB477FEDD9A" modified="2014-06-11" version="1">MAENKSVLEIRDLHTSFFTHLGEVKAIRGIDLRIGSGETLGIVGESGSGKSVTSLSVMRLLLHPGRVVKGEILFKGEDLLKKAEHEMTKIRGNNIAMIFQDPMTSLNPVLRVGFQIEEALLQHQRLTKKEAAVKAIEMLETVGIPDAKRRAACYPHEFSGGMRQRAMIAMALSCRPELLIADEPTTALDVTIQAQIIRLIKELGQSTGTSTILITHDLGVVADICSRIDVMYAGLVMEEGKTDDVFFNPAHPYTMGLLRSIPNVATGARHRLIPIPGTPPDLLNPPQGCPFSPRCSFTMNICTRHCPGYYQVGEGHKAACWLLDEHAPRCGRYDAMKGGISSIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9I7</accession>
    <name>A0A011A9I7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycyl-radical enzyme activator family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442048.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.871"/>
    <dbReference type="HOGENOM" id="CLU_058969_1_1_0"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="16"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="253" mass="28252" checksum="09FB2FC39D115523" modified="2014-06-11" version="1">MAVKGRIFNIAHYAVHDGPGIRTTVFLKGCPARCLWCCSPQSQSFEIERSAGGEKIFGRDVTAAELFAEVRRDAPFWRRSGGGVTLSGGEVMAQPDFAVEFLDICRAHNVHTAIESCLLASYDAAMRIAERTDFIQFDLKAMDTKLHKRLTSRGNEDILENAMAVLRGGIPVLVRFPLVPGLNDAEENIRAMGSFLESGREGVSLEVLRYHRMGVGLYEELGRSYPLEDVDPPTDEEYARVKEILNNYRIRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9S8</accession>
    <name>A0A011A9S8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.947"/>
    <dbReference type="HOGENOM" id="CLU_762282_0_0_0"/>
    <dbReference type="OrthoDB" id="1857502at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040572">
        <property type="entry name" value="TackOD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18551">
        <property type="entry name" value="TackOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="247"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="363" mass="40924" checksum="C84EC8B4609D0B42" modified="2014-06-11" version="1">MIRFGLWLLVISFFCTKFLTFIDAFALAVIMEREPQTDETCYDCRDIRSYNRFVFDDKEMAAATKWIRNLQRRGYTEHTAIYDRIRLCPKCQTGHLNYVDVCPNCGSLNIAKKRMLHCFTCGNVAPESDFRRDFSLVCPRCDTKLRHIGSDYDHPLESYQCEDCGSSFVEADVKVSCLNCGSQSLPGELTINNFYGYRLGERGEEAVRTGIISEDFTLFGGTNVVSIQTFCSVVKWLSSFRGRYPDAGFSLLRVKLIGLSEAEDVIGAAELRKLIAELDTRIRASVRETDITTLDEDGTFWLILPRTSLDGGTALAKRLEEMSSLFGEQAAGKLRLSAKCFMVSDAVAKVPPQELLKKLAKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA80</accession>
    <name>A0A011AA80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable glycine dehydrogenase (decarboxylating) subunit 1</fullName>
            <ecNumber evidence="4">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glycine cleavage system P-protein subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine decarboxylase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine dehydrogenase (aminomethyl-transferring) subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gcvPA</name>
        <name evidence="5" type="ORF">Cloev_1081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvP family. N-terminal subunit subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445393.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1150"/>
    <dbReference type="HOGENOM" id="CLU_004620_0_2_0"/>
    <dbReference type="OrthoDB" id="870147at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00712">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006815">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="440" mass="47108" checksum="DA338F79795A8F47" modified="2014-06-11" version="1">MGSYVPSTMEQRLEMLKAVGVASFDELYADVPESMRLKEGALDLPDGMSEMEVLARMKEMAGKNKVFPSIFRGAGAYCHYIPSIVKRITSKEEFVTAYTPYQSEISQGILQSIFEYQTMICELTGMDASNASVYDGATAAAEAAAMCHDRKRSKVVVSGAAHPDVIKVMRTYCFGSNSECVVVPPKDGGTDLEALKAAMDDATSCVYVQQPSFSGILEDCTAAAEAAHAAGAKFIMGINPIAAAIVKTPAECGADIAVGEGQPLGIPMGFGGPYLGFMACTEKMQRKLPGRIVGQTSDAKGNRCFVLTLQAREQHIRREKASSNICSNEALCALTAAVYMAVMGPEGMRKTAEQCFAKAHYLAARITSLPGFKMVNPGEFFHEFVTTSPVCAKKLLDALEEKGILGGLPVEGGILWCATEMNGTEQIEELVSVLKEVSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAA5</accession>
    <name>A0A011AAA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Selenocysteine-specific elongation factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">SelB translation factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1109</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711222.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1182"/>
    <dbReference type="HOGENOM" id="CLU_023030_3_0_0"/>
    <dbReference type="OrthoDB" id="244339at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015190">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015191">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004535">
        <property type="entry name" value="Transl_elong_SelB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09106">
        <property type="entry name" value="SelB-wing_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09107">
        <property type="entry name" value="SelB-wing_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00475">
        <property type="entry name" value="selB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="5"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="636" mass="69308" checksum="971AC6BF6B870178" modified="2014-06-11" version="1">MANNEYPFVIGTAGHIDHGKTTLVKRLTDVDCDRLAEEKKRGMTIELGFAPFTLPSGQTISIVDVPGHEKFIRQMVAGAAGVDAVMLVIAADDGVMPQTREHLAILSLLGIKNGLTVINKIDLVDEEMLEMAVDDAKSLLADTFLADKPVIPVSAYTGAGIEELKKALQRMTETADAKSRKGAFFLPVDRAFHISGFGTVVTGTAINGEVREGDEVEVMPRSFPSKVRSIQVHGAPVSVATAGQRVAVNLAGISLSDVGRGDVVTAKDCFTASKCLDVSIRLLPSAEPLKHWQRLRLHVGTTDTVTRVSLLDREQILPGESAAAQLITEDPVVASMNSCFILRTYSPLVTVAGGKILMPAGERPKNRQSKTALLEYLDRLSEEPQLKERLLALINYKGLINAADAARMNEINIAELMRALSPLEARGEIGVIRGGSAVLLSKGKMEELGSGLAKALASFHREHPERKGMPAEECAKAIDLQDTKFTRELLTLFEKQGVIKFEDERARLANFEPFDEELFSANVTALKKYAVKMGYSMPSVEEAQAALGFTAEEMKRIIAYLKEKKELALITGAFLLFLEIEADFKEKLANISGDITLAAVRDATGSSRKYALPLLEYFDSKGITRRVGDKRILMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCL1</accession>
    <name>A0A010YCL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cobQ</name>
        <name evidence="6" type="ORF">Cloev_0079</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441259.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.93"/>
    <dbReference type="HOGENOM" id="CLU_019250_2_2_0"/>
    <dbReference type="OrthoDB" id="744477at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="258"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="512" mass="56107" checksum="F0CFCA6E1C635791" modified="2014-06-11" version="1">MKNCTGIMIQGTSSDAGKSFITTALCRIFSDMGYAVCPFKSQNMSNNSCVTPDGLEMGRAQGVQAEAARVEPRTYMNPILLKPRKDTSSEIVLMGKVFDAPCDKNYYRTFTMGKGLETLREALALIDEKYEVMVCEGAGSPAEVNLNAAEIVNMRVANEADIPVLLVADVDRGGAIASVVGTLELLGRDRRRVKGIIFNKFRGDLSLFEDAVAFTEKKTGVKVVGVMPWLTDIVIEGEDIMSINWTRGGDGQAGEKLRVGVVKFPRVSNHTDIEAFRFEPDVEIVELAAPAQTASLDAVILPGTKSTVLDMKYLLDSGLADGIRRFYRHGGTVYGLCGGYQMMGEEIDDRFLRDNDKIPAIEGLGLLPAATAFGEEKTTVRRRGHAIHPCFKGETPVEGYEIHFGETRPLRDEPGFAPLFELDGKPDGLADGELRAAGSYLHNAFHNDLFRAEWLNRLRKKRGLPERGPVSTTAAKEAAYDALAAQARKNLDIDYIVKEIMRLTKAPKEGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCM6</accession>
    <name>A0A010YCM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin-2 methylase</fullName>
            <ecNumber evidence="6">2.1.1.130</ecNumber>
            <ecNumber evidence="6">2.1.1.151</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0094</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.130" evidence="6"/>
    <dbReference type="EC" id="2.1.1.151" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441289.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.108"/>
    <dbReference type="HOGENOM" id="CLU_076014_2_1_0"/>
    <dbReference type="OrthoDB" id="1209876at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043781">
        <property type="term" value="F:cobalt-factor II C20-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030788">
        <property type="term" value="F:precorrin-2 C20-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11645">
        <property type="entry name" value="Precorrin_2_C20_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012382">
        <property type="entry name" value="CobI/CbiL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036427">
        <property type="entry name" value="Precrrn-2_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="230" mass="24955" checksum="230FF85734387DF8" modified="2014-06-11" version="1">MKFTVVGVGPGDPELVTLKALRIIKEADVVLTPYSPRGKFSVAEQIVRANLPDTETTPITFPMLTDAEEREKFLLGELERIGASWRGAKSAVLPVIGDSALYATGSYLFDAWKKIAPELELSLVPGISAHQLAASRIGSFLAMGEDIFSVVPCIDDREGIVAALRRADSAALYKPCILKEGLAGVVAEAGPWRRMARIDRAGLADEKIYEGEAALTPAEEYLSILLLWRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCP9</accession>
    <name>A0A010YCP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe2+ transport system protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709194.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.129"/>
    <dbReference type="HOGENOM" id="CLU_150646_12_4_0"/>
    <dbReference type="OrthoDB" id="2047422at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="76" mass="8283" checksum="36613B24746FF091" modified="2014-06-11" version="1">MRTLKEAKPGESVSVVKVHGAGALRRRLLDMGITKGSRIDILKAAPLGDPIEVTIRGYELSLRKSEGEMVEVEPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD31</accession>
    <name>A0A010YD31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RarD protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0236</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441412.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054508_1_0_0"/>
    <dbReference type="OrthoDB" id="1391352at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="153"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="299" mass="32950" checksum="700AF89E3C76FECF" modified="2014-06-11" version="1">MTIPQKGAAAAFLSYLWWGSMPLYWKALSSVSSSEILGHRVVWSAIFTFALIAVTGQWHKTTAFAVKNKRKTLWLFLGGYLITLNWGLYIWAVNAGRILETSLGYYINPLVSMFFGMLFFGEKLRRAQRIAIAIAAAGVCIQIITIREIPLVSLGLALSFGLYGVLKKAVSIEPSVALLIETLSAAPAALAYLCWLQHTGAANFPYSLTTDLLLAGTGVMTSVPLLLFAYAAQRIKLTTIGFIQYVSPTMTFLIGTFIYNEPLSIHRIITFACIWSALAVYSADTVVCAGRERRRLEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD36</accession>
    <name>A0A010YD36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Deoxycytidylate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709402.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.261"/>
    <dbReference type="HOGENOM" id="CLU_047993_2_3_0"/>
    <dbReference type="OrthoDB" id="1544522at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="159" mass="17423" checksum="7DCD8729D7A1DCB3" modified="2014-06-11" version="1">MTNRPEWDIYFLLMAQVAASRSTCLRRKVGAVLVRDRQILSTGYNGAPRGVSHCEQAGCLRERLGIASGERHEICRGSHAEINAIAQAAAAGTATAGSWLYCTHEPCIYCTKALINAGCEKVFFLYPYPDELARAVMAESGVESIWVDPQTLPKDIFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD54</accession>
    <name>A0A010YD54_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="6" type="ORF">Cloev_0256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709426.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_2_1_0"/>
    <dbReference type="OrthoDB" id="1278103at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="189" mass="20403" checksum="41578000A9E0536B" modified="2014-06-11" version="1">MIAEIIRNTKETQIELTLSDESRERSIDINCGFLSHMLDLLCHRTALGLVIKARGDVEVDSHHLAEDAGIALGQALRKIAAAAPIRRYGSALLPMDGSLARVALDFSGRGGLWWKGEFPSQKCGDFDMELVPEFFAGFAREAGLTLHIALLETDNSHHAAEAAFKGVGLALKEALAPAQTAPSTKGLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDL9</accession>
    <name>A0A010YDL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH:ubiquinone oxidoreductase 24 kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709064.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177584_0_0_0"/>
    <dbReference type="OrthoDB" id="1412344at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="82" mass="8769" checksum="DFC955C2D4C58A03" modified="2014-06-11" version="1">MTDVVICVGSSCHLKGARRVVEGLTKLVTERGLTEKVNLSGSFCMGRCEEAGVSVKVNGEIHFVDPDHIEMFFDDVIAGGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDT0</accession>
    <name>A0A010YDT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">VRR-NUC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441697.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129193_0_1_0"/>
    <dbReference type="OrthoDB" id="2021091at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00990">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="4">
        <location>
            <begin position="13"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="128" mass="13860" checksum="8F7692C3055761B3" modified="2014-06-11" version="1">MASSVALPVPKEHEEQKAFMTLAECLLPSEFRPLLWATPNAAKRSPKTASIMLAEGLKSGVPDLFLAIPCGGKAGLFIEMKRRRGGTVSAEQKAYLALLRKMGYRAEVCRGCDEALAVFKDYLGISDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDV0</accession>
    <name>A0A010YDV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484836.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171754_0_0_0"/>
    <dbReference type="OrthoDB" id="2017584at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="111" mass="11954" checksum="1272B14018C8F28E" modified="2014-06-11" version="1">MFKINLSPQVREDTLSVSVSGSTIIINGQTFDLEPLQDGATLPCDAFATEFIVSDVARSGDTIELTLLFPIPSNATEEQRFPKPVYVDASGQVIAIDELGAEDQAIEPEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE18</accession>
    <name>A0A010YE18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sugar diacid utilization regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0573</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441821.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.613"/>
    <dbReference type="HOGENOM" id="CLU_043769_1_1_0"/>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008599">
        <property type="entry name" value="Diacid_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05651">
        <property type="entry name" value="Diacid_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diacid_rec" evidence="2">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF_2" evidence="4">
        <location>
            <begin position="145"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="3">
        <location>
            <begin position="318"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="381" mass="42890" checksum="DD1491BEBF1FC952" modified="2014-06-11" version="1">MQFPKRSAMNIVQEIGDVIGEKINMMDSEGVIIASTDPARMKTFHAGAKKLVEERLDELVVRYDGEFDGARQGINLPITFEEKIVGVIGVTGPYEKVRKYGQIIKKMTEILILDIALSEQLGIENRARSRFLNDWVHASPAEVATLAESARSLHIDITIPRRVLLLSVVPLRNDGATETQVTIEGAERRVSEFCGAGKDIIVFKLESRIALLVPAQSDEGMLTFASGLKREVEGCCPVSLAIGIDAEYRGYQYMAAAFERAERALRTCLRSPSRQPRLYDSLNMEIFLGEIPDAVKAEYVKRIFRNCAPEEIAACISMLELYYECEGSVSEASKRLFIHKNTLQYRLRRLADTTGYDPRSIKFSSLYYNAIHFYRDISNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE50</accession>
    <name>A0A010YE50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase (GGDEF) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.654"/>
    <dbReference type="HOGENOM" id="CLU_772981_0_0_0"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="235"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="392" mass="44195" checksum="0B213CA230E6B074" modified="2014-06-11" version="1">MRKMTNPAELAENRPRQPDKLKKRVFSDNGHEISKINQRMLRSLSFVLSVLMPSLFFLSLRLPALNELDRPYAFFFLMSVLVYFASGELREGAVLPLIYLYFLSLVVFSVYGGIFLHVSHPPIFIFVTLLIFPMIVIDRRWRINMAIVFVCSVYCSLSFLYKPFSYSVAALINVTISSVLGIAIGRHLTAIKLENIETRRQLALQRDTDILTSLPNRRKLFEVLGEMELEDSLTPLTGVIMIDIDNFKNYNDFYGHVKGDECLSVVGSCLRLYSEKYAVAFFRYGGEEFIGLSTEYSYKEIGAIAESLRETIRGLDVRHRGSSLGVVTCSVGYAEKAVCASLGHEELIVMADRALYAAKSMGGDRAAGFLEATENEGGECLTLRRKTRGQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE68</accession>
    <name>A0A010YE68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Citrate lyase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710371.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.676"/>
    <dbReference type="HOGENOM" id="CLU_044864_0_0_0"/>
    <dbReference type="OrthoDB" id="1107373at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="5">
        <location>
            <begin position="5"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="294" mass="32091" checksum="DFD59B445D616665" modified="2014-06-11" version="1">MKASRSMLYIPGDAPGMIQHAPIFGADSVLLDLEDAVALTEKDGARRMVARFLKDFDFKDLFVTVRINAADTEFFEDDLKEIIPCAPEAVRLPKCNGPEDVVSADKRISAIEERCGMRHGAVKIHAMIETALGLEKAFDTASASPRVTALTIGGQDFTADMGVRKTKEGRELFYARCRVAAAAHAAGVDSYDTVWADLQDNEGLLRETKEIVGLGFTGKACIHPSQVSVIHKAFMPEEKELRKAMRVVEAAEKAKREGKGVIAVDGKMVDAPVIARSAHLLELAELYGFDREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE76</accession>
    <name>A0A010YE76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441889.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.687"/>
    <dbReference type="HOGENOM" id="CLU_001771_0_3_0"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="7">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="733" mass="78838" checksum="EBD62CFBF0B96702" modified="2014-06-11" version="1">MEEIKKTEQEIKWNFRVLGMTCTTCSRIVERALKKVPGVIFASVNLATESAFVLAEPGVREDALEAAVKKSGYEIVKDVPADLDEMRYREARRNLIEILVIGIPLSFLMLLHMFFGYHFPWYGPLEIVFGAAAIFWCGRKTIGGAWIALRHGHTNMDSLIALSAAASWLTAIFNIMGFAIPSFGTVGVMIMMLHLTGRYIESHLRDRAAKQVKTLLTLQPREARVMGDDGETIMVPIEAVKPETIMQVNPGERIPLDGVVIEGKSGVDESLLTGESLPVAKSEGSEVTGGALNTYGILTIRTTKVGEDTFLSKMLELVREAQGGKVPLQALADRLTLKFVPAVIGLAGLSAAAWYFFFPQLHALIAPLAAMMPWPTNLSTPAGAAAYAFIATLVIACPCALGLATPLALVVSTGEASRAGLLIRNAEAIQTLKDVNFAILDKTGTITKGEPKVTKWQAPEAALRYIYALESNSGHPLARAVTEAAGIHPADRADSLTETPGEGVTGKWGDTEWFVGRPLDRSRWSDASSLAVTLVEVRRNGEPVGYFAITDPIREDSPSAISELKKMGVTPMMATGDAKETALSIAKEAGIEDVRWEVRPEDKLSLVHEAQSEGRRVLMGGDGINDAAALKGAEVGIAMGGGMDLAVDSADIVIMRGGLSRIVAAIKISSKTWRVIRENLFGAFVYNIIAIPMAMAGLLHPIAAEFAMAASSITVILNSLRIAGSAENKKEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE88</accession>
    <name>A0A010YE88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdsB</name>
        <name evidence="3" type="ORF">Cloev_0657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441904.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.702"/>
    <dbReference type="HOGENOM" id="CLU_065038_0_1_0"/>
    <dbReference type="OrthoDB" id="1345588at2"/>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="240" mass="26370" checksum="DDC161FC52F0E4DE" modified="2014-06-11" version="1">MKTLAVIPARYSSTRLPGKPMIEIAGVPLVIRVLDNVSACASVDRVIVATDDERIAELVSRHGGEAVMTPPELPSGGDRVAYVSRIVPSDYVLNVQVDDPLVGADMIDPLVAALDGDSSVMLALLTKRIDDMDEVRANNIVKAVFDGDGRALYFSRSPIPYPRSEGGVWYKHIGPYGWRRDFLLEFAASEQTPLEKTESLEMLRVIELGHTIKCVTAARDTIEIDTPEDLLKIEKYFSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE97</accession>
    <name>A0A010YE97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid:ferredoxin oxidoreductase, gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710449.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.712"/>
    <dbReference type="HOGENOM" id="CLU_087284_0_1_0"/>
    <dbReference type="OrthoDB" id="1777574at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="14"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="187" mass="20129" checksum="0E428321D42EDB25" modified="2014-06-11" version="1">MTTFTRTLFCAGFGGQGVMVLGQLVAYGAIEEGRHVTWLPSYGPEMRGGTANCGVTISDGEISSPFVTRADVVVVLNQPSLDKYEPTVKKGGILIYNEDMASYHAARDDIRVIPVHAARIAESVGNERALNVVLLGVLTAVSDFIADETARNVIREKLGAKKPQFLESNLKAYEAGKELAKSLTAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEA1</accession>
    <name>A0A010YEA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable butyrate kinase</fullName>
            <shortName evidence="8">BK</shortName>
            <ecNumber evidence="8">2.7.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Branched-chain carboxylic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">buk</name>
        <name evidence="10" type="ORF">Cloev_0672</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + butanoate = ADP + butanoyl phosphate</text>
            <dbReference type="Rhea" id="RHEA:13585"/>
            <dbReference type="ChEBI" id="CHEBI:17968"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58079"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.7" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441924.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.717"/>
    <dbReference type="HOGENOM" id="CLU_048716_0_0_0"/>
    <dbReference type="OrthoDB" id="537106at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047761">
        <property type="term" value="F:butyrate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00542">
        <property type="entry name" value="Butyrate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011245">
        <property type="entry name" value="Butyrate_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060:SF3">
        <property type="entry name" value="PTHR21060:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036458">
        <property type="entry name" value="Butyrate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02707">
        <property type="entry name" value="butyr_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="358" mass="38367" checksum="C822B873271396F3" modified="2014-06-11" version="1">MRIFALNPGTTGIKAAMFEEARALWTENIDYPPGCAMGYASLDREAEEMIRGAILAFLASKSACIQDIAAFVGRGGLLHPISGGTWTVNEAMLADLRSNRYGSHASNLGAIMASRLADDAGGKPAFTVDPVVVDEMIPEARISGMPEIPRYSIFHALNQKAVARRAAAQLGKRVEECSFIVAHIGGGITVGAHRSGRVIDVNNALGGYGPMTPDRAGTLHMLDLVRMCFSGRYTFDEIKKKIVGGGGLRAYLGTNDFREIMALVKSGDERAALLVRALALQISGEIAARAAALCGRVEMIILTGGLAFDEDLCAMIEERVGWIAPLMRIPGEGEMQALAEGALRVLRGEEEALVYERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YED8</accession>
    <name>A0A010YED8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tripartite ATP-independent periplasmic transporter solute receptor, DctP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441958.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.756"/>
    <dbReference type="HOGENOM" id="CLU_036176_1_3_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457574" evidence="2">
        <location>
            <begin position="22"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="327" mass="36181" checksum="7DEC2BEB1286E92E" modified="2014-06-11" version="1">MKKLLAAVMFMAITAASAAFAAPEYTIKVGYIGSDTHPTMQAMKAFAKDVDTGSKGKIKVELYPNAQLGGDRELCEGVQMGTIQMAIPSTSALAGFDKRIQVLDLPYLFTTRKAAFDAVDGELGQKLNSYLAKKGFEVLGYQENGFRHVTNSKRPIKSPADLKGLKIRTMENPMHIAFFKELGANPTPMSWGELYTALQQGTVDAQENPYAMIDDGKFYEVQKYVSETGHVFSYEILIANKKFMDKLPADLRKVVVDAAHKAIMAQRASLEKEEAAFKAKVTKAGLKANELTPEQKKPFVEATKKVYAQFEKDLGKEIMDIARKVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEL2</accession>
    <name>A0A010YEL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ethanolamine utilization cobalamin adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710673.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.825"/>
    <dbReference type="HOGENOM" id="CLU_093470_1_0_0"/>
    <dbReference type="OrthoDB" id="1407310at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006580">
        <property type="term" value="P:ethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009194">
        <property type="entry name" value="AdoTrfase_EutT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012294">
        <property type="entry name" value="ATR_EutT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="90"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="254" mass="28992" checksum="F91DA5F2039F402A" modified="2014-06-11" version="1">MRVITEAMLRDELKRSEIAEYRVPAGMMLSPAAREYLQQRKIKIGRESASERPQAAAPAEKKPETALPPQAKYRDYETGALYLEKPEYMTQIEGDMLVVKNHPRIAFRGKLDSLQALIVLDQAILSEKAGYGKVIADLDDILGVLREIMRCDALNEPLRVEKIIGFTSAELRERSHAPMKFFHVKYMRLPDYKMGVAYALLNQLRAAVREAEVTAVNAFKNGTNYERQDILEIFNRLSSAVHIMMCLYLQENNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEM1</accession>
    <name>A0A010YEM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710687.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.835"/>
    <dbReference type="HOGENOM" id="CLU_042399_5_2_0"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457853" description="YkuD domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="32"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="178" mass="19736" checksum="9D73F6AE621D40B9" modified="2014-06-11" version="1">MKKIFIIALFLLFACAAAASAASPWSPKAGEYWIKVNKQQLRLTLFKGGEVVKSWPVSIGKGRGKVKSSRLDLITPTGTFTIYRVIPDATKLVFDPAWFDEPGKAAPGAYGSKLISFYNKWEIAIHGTNNPGSVGRWATHGCIRLKNPDIEDLVNYVKPKMKIVIVENNDIPFLKETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YES6</accession>
    <name>A0A010YES6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase, histidine kinase/DNA gyrase B/HSP90-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710793.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125323_0_0_0"/>
    <dbReference type="OrthoDB" id="1776812at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="183" mass="20110" checksum="FE631328F7E0D848" modified="2014-06-11" version="1">MLEDLSAHVLDISENSTMAGADEVEITINEDEREDLLLFSVKDNGRGMSPEFVAKVTDPFTTTRTTRRVGMGLPFLRQSAELCGGALVIDSAVGVGTTITATFRYGSVDRPPLGDMPATVMTLVMGSPNVHWKYRHIINGREFLLDTDEIIEALDGDREMLASPDVGLWLRDNIREELAALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YET7</accession>
    <name>A0A010YET7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative efflux protein, MATE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.905"/>
    <dbReference type="HOGENOM" id="CLU_012893_5_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="454" mass="48901" checksum="24F4B0DEDD0A9A93" modified="2014-06-11" version="1">MLLNKKYEIDMCSGAILPKMLLFAIPLMCSSILQLLFNAADIIVVGRYAGDNSLAAVGSNTPLIGLLTNLFIGLSIGTNVLAARYYGAKAEEDLAKTVHTSMVLGIVSGLFLSVAGIAGARRILIWMQTPEEVLGLATLYLVIYFLGMTAMMVYNFGSAILRAVGDTRRPLYYLVAAGIINVILNLFFVINLRLDVAGVAIATVISQCVSALLVVRCLLREGGGIRLVPSMMRIDRAKLAQILKIGLPAGIQGVLFSLSNVVIQSSINSFGAVVMAGNSAAANIELFVYFAMNAFYQAIISFTSQNYGAGRIKRIYKVLLRGQACIVVIGGLLGVLVVIFGRTLLGVYSSSGAVIDAGMQRLWILCSTYVLCGMMDGMVGTLRGLGYSVLPTVVTLLGACGLRLVWIATLFQAEAFHTVTTVYLSYPVSWAVTFGVHVLCFRWIMTKRLLVRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF53</accession>
    <name>A0A010YF53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="8" type="ORF">Cloev_0975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710981.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1045"/>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_0"/>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="7">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="156" mass="17582" checksum="04F9A2C89353403C" modified="2014-06-11" version="1">MPRKGHVKKRITPPDSVYANPAITKFINCLMLDGKKSTAERILYGALDLAGSRLNLEPAEVFEKAMTNVRPLVEVRPRRVGGATYQVPVEVKPDRAQALAIRWIINFSRSRKGIPMVERLARELGDACKGEGGSVKKREDTHRMAEANRAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF90</accession>
    <name>A0A010YF90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid:ferredoxin oxidoreductase, gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711055.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1095"/>
    <dbReference type="HOGENOM" id="CLU_087284_1_1_0"/>
    <dbReference type="OrthoDB" id="1603697at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="15"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="193" mass="20652" checksum="1F4B40BE8C948750" modified="2014-06-11" version="1">MKNNDTKSILLVGVGGQGTILASKILSEGLVRKGYDVKMSEIHGMSQRGGSVTTHVRYGSRVASPVVPEGEADVLVAFEKVEAARWLRYLKKGGTLVVNDFEIYSLPVLTGAAEYPEGVTDKLKAEVPNTKCFNAGKVAESLGNIKAQNVVLLGALVKAMGLEDLDWKAVLSETVPPKLLELNIRAFEAGLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFC2</accession>
    <name>A0A010YFC2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gcvH</name>
        <name evidence="6" type="ORF">Cloev_1080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442373.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1149"/>
    <dbReference type="HOGENOM" id="CLU_097408_2_2_0"/>
    <dbReference type="OrthoDB" id="1773485at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="125" mass="13524" checksum="8486687B9D6B9445" modified="2014-06-11" version="1">MNIQSDLKYTKSHEWVKDLGGNCALLGLDDYAQDQLGELVFINLPEVGDEVTAGEAFGDVESVKAVSDVFSGVTGKVAEANAELADKPQKVNEDPFGAWLIKVEDITAYGDLMDAKEYEAYCASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFF5</accession>
    <name>A0A010YFF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711241.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_2_1_0"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="145" mass="16510" checksum="7273DCB8E937A7D8" modified="2014-06-11" version="1">MKKGGMNVTYKTGLKNMDMARVRDMLSKTYWSPGIGLAEVTKAAQNSALVIGAFGEEGRQIGYGRVISDRTRFAYLTDFYVEEEYRGAGIAQEMIDRVLGAPELSDVYQWLLITKDAHGLYRKKGFVPTKRPQDLMEIRRPRPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS87</accession>
    <name>A0A010YS87_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 12">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0082</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 12"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709844.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.96"/>
    <dbReference type="HOGENOM" id="CLU_035731_0_0_0"/>
    <dbReference type="OrthoDB" id="677575at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG77983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="324" mass="35679" checksum="D3484922C6CA452A" modified="2014-06-11" version="1">MIVRPRRLRRNKIIRDMAAETRLSPSMLVYPVFIREGKDIIEEIPAMPGQRRCSPDTFPRILEEVRRAGVNSVLLFGIPEHKDERGSEAYNENGVIQQALRTGKKHFPEMCFIGDVCLCEYTSHGHCGLLKGETVDNDPTLELLAQTALSQAQAGADIVAPSDMMDGHVAAIRAKLDGAGMDDTLIFSYAVKYASAFYGPFREAAGSAPSFGDRKSYQMDPRNVREGIREALLDIEEGADMIMVKPGLPYLDVLRAVKEVSEVPVGAYCVSGEYSMIKAAAERGWLDEKRVIAESAVCLARGGADIIVSYFAPELAKMMKEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSD4</accession>
    <name>A0A010YSD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709236.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_626827_0_0_0"/>
    <dbReference type="OrthoDB" id="763845at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="256"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="449" mass="49341" checksum="F0F56211A286B136" modified="2014-06-11" version="1">MKIFKNGTVVTGDGKTVLEKANVIEVDGLVADVNLYYDENLESYAEEVVDCGGKCVMPGMINHHQHGVTFGTMFASGCVSYGREFILDHLDRSLLQGHTTVLNVDGFATMDEVEEAQKAHPIRIKTATTHAPINYHAGELCDGKGFLPKHKEMTVEKMLADGAVCIGEVGGGHTLGGGGQDYLYIPRAVKERKGKDIDYLQARAMKLSVLGRYIEESYYDRDRVAAALKEAKLDSFLTPEETKDIVYKTTLASVKVALDGYREAANLAKRYDVPLMIHNAPTSKYIVHEIAKMGLNTLICCHSNYLFTTEECVENGRYLKQFPGVVLDAAVHDPWGAKHLVATPDNLYAFYENDLIDVISTDFAAGHSDSMLEAIQHAALEKKLVGLAKAVRQGTSRVTEVLPLLAPNLGELKKGYTADIVVTEYPQLKNVERVYIGGKLVAKDGKVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSD9</accession>
    <name>A0A010YSD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709245.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.162"/>
    <dbReference type="HOGENOM" id="CLU_001681_2_1_0"/>
    <dbReference type="OrthoDB" id="117507at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="759" mass="83068" checksum="6D580200DBF9AF73" modified="2014-06-11" version="1">MEKFNSIGLKQSFVDAREKVTGSARYLDDLEFPGLLTGKILRSPYPHARILSIDTSAAEALPGVKAVITAKDCPQNKFGMEIADVDMLAVEKVRYVGDEVAAVAAENDEIAREALKLIKVEYEELPVVDDPVKAMEKDSPLVHEEKGTNVAREYHIQRGDIEADFASCDYVFEKEFSTHRVSGLYLEPFGAVAQWESNGRLTVWTGLQSAFQGRNEIAKALGIKPTQVTVKSPFIGGGFGAKIWIRNFHPIAAVLAKKTGRPVKILLTRDEEQLTTRPRIAPRMKVKLGMMKDGTMVCKQATIVADNGAYSWAAPKVLLNLSMRTDCLYRYKSSKCDSYLVYTNLIPTSGFRGYGNSQMHFAVESFIDECCRKVGLDPVEVRLKNCVHKGDMTLHRWHIKSCELSECIRIAAEKIKENRLPAEEQDGRIKRGIGVACMTHVSGNRGGDKFDGSSAMIRIHEDGEVFIFSGEADMGQGAKTVFAQIASERLGVPIGDITVMPLDTDVSPFGMGTYSSRVTTVGGKAVFLASEKVLDQVLTLAAEMSKRQRDTMYMENGLIKCSRDPSVLMTLKEVAAKAIRSRAGVPLTAYVTYDPPTEGADKDFYGDYSSAYSFGAHGVEVEVDTHTGKVKVLRVVAVHDVGKVINELGLHGQITGGVAQGIGWCLYENMLFKNGVPATNGLHGYTFMTIKDMPAVEGIAIESNDPIGPYGAKGVGEPTLIPTAPAIANAIEDACGVRMRDLPITPEKMYWALHSPKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSN2</accession>
    <name>A0A010YSN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative exonuclease of the beta-lactamase fold involved in RNA processing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441418.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.264"/>
    <dbReference type="HOGENOM" id="CLU_009673_5_2_0"/>
    <dbReference type="OrthoDB" id="580619at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="13"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="254"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="551" mass="61730" checksum="A758840A67B6BC04" modified="2014-06-11" version="1">MKLRILGAAGEVTGSNYMIETDGYKVLVDCGTHQGMDEEKHEEEKFPFSPADIDAVLLTHAHIDHSGKIPLLVKQGFKGKVYCTHATSQLIEILLRDSAHIMREDAEWRSRKNARKGLPKVEPLYSESDVEDALAFRHPIPYDEMVEIYPGLKVRYREAGHILGSAIIETWISEGEGQKPVKAVFSGDLGQFDGVIEKPPAIVEEADFVLIESTYGDRLHKSLEDTRAEFQSAMEDAIRSGGKMLVPTFVVDRAQRMLYEFKLLQKKLPDLKMPNIYLDSPMGVRTTEIYSAHTTLLSRELKELLMNGEDPFEPKGFSFVRSADESRAINDMAEGIVLAGSGMCSGGRIMHHLKHNLFKKDTHVFFVGYQAYGTLGRRLVDGAKSVRIAGEEISVKAKFHTLNGFSAHADRDDLLKWAGHFPKKAQFIIVHGEPKSAESLALGLKDSGYSTRIPAIGDEIDLLAPAPEKIAMPVISPRILDRIQFNSKDVEDLLNLISARTARMQQTVIQNEEQYKNIMPLLISARTLLEAAAALSDNRIEYKEEKREEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSV2</accession>
    <name>A0A010YSV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein, gamma-carboxymuconolactone decarboxylase subunit like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441493.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.347"/>
    <dbReference type="HOGENOM" id="CLU_070025_0_0_0"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="27"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="165"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="249" mass="27878" checksum="14D474BFAFC104F2" modified="2014-06-11" version="1">MAITAAAKEYHERMFPGYRSTFLDTDPEFIERFDNFAFDEVVNSDDLDGRTRMTAILASLVGCQGIDEYRAILPAALNFGVTPTEAKEMLYQAAAYLGIGRLYPFLRAANEILAERGVRLPLPGQSTTAAEERLAAGERAQIEIFGDGMKDFWRSGPEDSRHINRWLTDNCFGDWYTRGGLDLRRREMLTFCFLAAQGGCERQLASHIAANIRLGSGKEFLIKVISQCIPFIGYPRALNALDCINKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSZ6</accession>
    <name>A0A010YSZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiamine pyrophosphate-dependent enzyme, putative carboligase or decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441553.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.398"/>
    <dbReference type="HOGENOM" id="CLU_013748_3_1_0"/>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="192"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="394"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="574" mass="61720" checksum="B2B37F81D348A2E6" modified="2014-06-11" version="1">MKASKAILAMLRAYDVTDVFGLPGETTLALYEAWEEYPEIKYHLTRDERNSVFMADAYAKATGRVGVCEGPSVGATHMVPGVVEAFQSCVPLIVITTDIDLKTGPKNMLTGFDQSALFKSIAKDSFTVTDASEIPHLFRRAFRTATTGRPGPVHIRIPMNTLEGEAADGEIYAQSRYSTFPGCRNSAAAADVTEAAALLAAARRPVMICGQGVVHSGAWKEAAALSKMQEMPVGSTINAKGCLNEHEPLSLGVIGARGGREWNNRMVKEADVILFAATSTDSANTDGWKLPSPNSGQKFIQIDIAERELGNNYDALPLFGDARETLTALTAALAERPRPDRGAWAARCAEEKAAHEKKLEAIMARCGDEPHPLSLVRAIERLTPDTAFFAVDPGSPAIYSSCFLRIARAGRRAAYNFSMGALGYAIPAAIGARCGTAAEAPVVGLIGDGSFGFCGAELETAARLGLKIIYVLFNNGTFGWIRGTQRVHTGAEITRNFRQFTDFAKVDYVKFAESLGLTGCRAGSMSEFEEIFAKCLKADGPCLIDVPLKPEDEQLPPVPAWAAAKIAKDEDMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT08</accession>
    <name>A0A010YT08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441579.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_10_6_0"/>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457681" evidence="2">
        <location>
            <begin position="27"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="452" mass="48291" checksum="F0213D3CA462FB8A" modified="2014-06-11" version="1">MKRFFLFIALAAALALFVIAAGTASAASVKTETGGAALKLSMKEALSLALAQNVSVVNASEDVRRAAGESQSQSSALLPKIDLAGSAAGTSDNSAGTQNTDERTLGAQLSYTLYNGGKNRALSEQGKLGVAQAGDYLYDTRESIVLDVWKAYCETLYRASVVTAVKSALDYYERAVEEETKRVEVGVATNLDLSRMRQQRAGSQAEYISAKNDLDSARIALCRLLQLAPETRLELTDGLHDDLSLAGTPLPESISVREYHARALERRGDYKKLAAQRKIDEKEIVVAASALKPSVSFSGGYGYDYKDTSDKILESKDEWSAKLSLSVPLFDGGKGAGDVTAARSKLTQSVNSLCDKEEAILAEITDCRLSLASAAESAAAAVTEVSFAKESLGYAEVGYKEGVNSQLDVIQARSDLTDADKKLAGYLKEYRSALASLWRAGGELIEKTIGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT44</accession>
    <name>A0A010YT44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709138.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_1_0"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="68"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="247" mass="28083" checksum="ED0F5553054FB55E" modified="2014-06-11" version="1">MKEDSVRSVERAFSILKAFTRDDYKLTLSELAERIQLPVTTTLRLANTLENLNMLHRHSDRCYSLGNQLYLLGSVAKANFRPQQIIYPYMKQIRDETKEAVSLYGVIGEDRACFEHVESLLSMQCVMRVGDRLPLWAGAGGRALLAFLGEEIIEREIKKAHKITPTTLFEPDKLRIELSNVRTLGYSLSYGDREEGILSVAVPIFNRRGELAFSFSVAGPIQRFTEEQALNLVPKIQKMCREVATQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT88</accession>
    <name>A0A010YT88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441747.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1999924_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="124" mass="15006" checksum="5EDE4E2CDB0C1E85" modified="2014-06-11" version="1">MKVLTPRPFGWWMKRYLDRVGSSDCRFGEYEELFFDPLRGFMCWEVSPGMRELYVTKVCGDGRFWRDKAYEMFAWAKERYGVRYLCCCTRRGPEAFCRLFGGDVFKVEERDGRPLFWIRTKELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTC7</accession>
    <name>A0A010YTC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0542</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484840.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="308" mass="33734" checksum="BF144569A02FA7EC" modified="2014-06-11" version="1">MTAAAQERILSYRGVAKSFGAQRALDGVDLEIKRGEIFGFIGPDGAGKTTMMRIAMGIINPDGGECMLLGSADRRRARVMAGYVPQLFSLYMNMSVMENINLFGSLYGKPVSEVVARAEYILSRVGLWGFRDRFAGNLSGGMKQKLALAIGLLNTPEILLLDEPTTGVDPVARREFWALLYQFNHEGLTIVVSTPYMDEAELCTRKLFLNNGKILDVGTTGELLSRYPYKLLSLDSGGREVRGWLAGRPHIVDANMFGSKYHIVTDDACGARRSVEAAFREHGGTPPGLRDIDPGLEDLFVAFAGKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTD8</accession>
    <name>A0A010YTD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DMT(Drug/metabolite transporter) superfamily permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441816.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_21_3_0"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="150"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="296" mass="31270" checksum="7FDCBF4F7BBCA7E0" modified="2014-06-11" version="1">MQAKRKKMLIGDLAVLLVALIWGATNVVIRDALGDITPFWFCALRFIIAWTAVMLIFGKRAMSMDLRAKAAGTFTGMVFICAYLAGAVGLLYTTAGNQSFIISMSVVFVPLSVWLFTRKFPGWHVAAAVVLCTAGMAGLVLDGDLSVNVGDLLSAGAMLFVTAYILLVQKFVTGSDPCGLACWQAFGGMILACAAAFLFEPIPARLSGAAWAAVIYAGTIGFALTLVLQTAAQKYTASTHVAILLSTSGIFGSAIGVIFIGEPMTWRIFIASALILAGVMAVEAIPALKKRAPTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTM8</accession>
    <name>A0A010YTM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710415.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2045609_0_0_0"/>
    <dbReference type="OrthoDB" id="1823975at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458157" evidence="1">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="120" mass="13302" checksum="37D520A96FCE3829" modified="2014-06-11" version="1">MKKFTAALIIILCFATASFAAFGKKGFVPDGDPIAYKGLKVTENGVNIILMNKGDKTVVFNAALAFLNNRRQEIGDVYIEKTTIEPGGEAAFKDLFLKGDYKACRKAESLRWTIYELEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTQ8</accession>
    <name>A0A010YTQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441935.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.730"/>
    <dbReference type="HOGENOM" id="CLU_014801_4_2_0"/>
    <dbReference type="OrthoDB" id="715502at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="506" mass="55877" checksum="975674FE4FBE300B" modified="2014-06-11" version="1">MEIILTGNDLTVEKVWAIAVEGARAEISREAEAKLEAARTLVYDLARDETPVYGFNRGVGWNKDRKIEADQIDDFNRKLIYSHSLGIAPEASEAEVRAVMAVRLNCLLQGNTGIQPAIARRYAEFLNAGIHPVIPERGSVGEADITLLSHIGLAMIGEGDVNYKGRRISSAEAHKLAGLEPVKLGPKDGLAIVCSNSFSAGQAALALKELKDLADTGEIVSALALEGLNGNTSPLDPSALAARKYRGQQYSAERIRKYLEGSYIYQPDPRRPLQDPLCYRGAAHINGTLRDAVRYAEEALLTQINSTDDNPCVLTEERRMISVSNFEVTSLSTAFELLAIVLSHVSRASCYRMIKLANPELTGLPRFLSHDGGASHCFGTIQKTFTMMDTEIRLLSNPCSVDYMALAGAIEDHANNTPLVVQKLRKAIDNMKYIYGMEMMHACQAVELRKRGQELELGRGTKIAFSEFRKELKLYESDRPLSPDIRKAYEFIDGGVLLKEVRDKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTS0</accession>
    <name>A0A010YTS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445243.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.740"/>
    <dbReference type="HOGENOM" id="CLU_031812_1_0_0"/>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="171"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="393" mass="42784" checksum="7CFDEEE2B0E358F6" modified="2014-06-11" version="1">MIMSKEIFGKAQSHITERAGEMAAFSDYLAAHPELSEAEYETSRLMTEKLRAAGFEVEYPYLGLPTAFMAKKKNGADKPVVAVMVEYDALPEIGHACGHNLHGTMALYAGMAVGEAMGDVAGELRVIGTPAEETDGAKIRMAGEGVFDDVDFAVMFHSFAGESFADYRSLGIDGFDFAFTGQTSHSAASPWRGRSAQSGMLLFIDALNMLRIHMHDYCRLAAYITEVKGAVNIIPDRAVCRVEARAPRQDIQRELTAAVLECARGAATATRTEVSWENFEGSFAPMLPNLTAEKLAEETMAEYGVICTNGHPATGSTDVGNVSYRCPAIQPEFAITTRNLDLHTREFAAATTSEEGHEALVRGARIIADICLKVFTDEELRKKIKAEFEAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU33</accession>
    <name>A0A010YU33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3298 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.847"/>
    <dbReference type="HOGENOM" id="CLU_049430_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021729">
        <property type="entry name" value="DUF3298"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037126">
        <property type="entry name" value="PdaC/RsiV-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11738">
        <property type="entry name" value="DUF3298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457945" description="DUF3298 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3298" evidence="2">
        <location>
            <begin position="149"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="239" mass="26629" checksum="292627C2D9B4E76C" modified="2014-06-11" version="1">MKYLRGTAAAFAAALLLGAAMTASAKEADVRFETLSTYSSEFRGFEAKIVTPVVTGLAVSAVQNELNDSFMQRARKLTADYENDVGEMMKDDPEFQGHMGVVLDYKVRTDNGKVLAVDLYEMNIAGSSSTVHSFYNFDKRSGKLIELGELFNGKADYTKVINNYIIGEMRRRNKKEKGIFWIAPQDEQGFRSIKPKQNFFINDKGNIVICFDKYEVAPGAAGSPEFELPRKVVGPYLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUN4</accession>
    <name>A0A010YUN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">Cloev_1008</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711028.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1077"/>
    <dbReference type="HOGENOM" id="CLU_053084_0_1_0"/>
    <dbReference type="OrthoDB" id="662686at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="17"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="268"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG78863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="357" mass="39253" checksum="5AC9B02D992BFB86" modified="2014-06-11" version="1">MEHDRHEIIVQESTPSYGKITVEPLERGYGVTLGNSLRRVLLSSISGAAVVAVRVEGVLHEFSTVPGVKEDVIELLVNLKHIPVRCHSTAVRTLHLESKGPKVVTVSDIDPDSEVEFPDPEAYICTLEEGHTLSMDIYVATGTGYAPIDRPRASYLPVDALQTDALFSPVQRVKYDIQDKRMGQRTDYDSLTLEIWTNGVVTPESAVIQASRILKGYYASIVDSLAGPGTSALDEIIKNDEASRATAMGGKPGFDVHSGLSGFPMGENSIYSRPVRDLELSVRSENCLLRGGVHMIGELVSRTRDDLLKIRNLGKISLKEIEEKLAKFDLHLSGDISTPIDDDDEDLDDNEQNLKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUN8</accession>
    <name>A0A010YUN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">Cloev_1013</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711033.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1082"/>
    <dbReference type="HOGENOM" id="CLU_014673_0_2_0"/>
    <dbReference type="OrthoDB" id="1075262at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="8"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="144"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="252" mass="28662" checksum="EF877A8D2DDC0832" modified="2014-06-11" version="1">MNRYAAEVSYDGGKFFGWQIQPGLSTVQRSLEEAVSKINGRHTPVAGAGRTDAGVHARAQVCSFDMERPWEPRRLLLAVNAHLPEGVSLMRAAAVPGDFHARFSAREREYRYFIWNASAIYPHIKGKACWIKPQRYDWARAAEAAKELLGRHDFKNFCRLEGGEHSTVREITQIRLIDRRPLVILRIKGNGFLHNMVRIILGNLEMAALGQITPRQIKELLDTRGSTRSDGGRTFPACGLYLWQISYDEKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUV2</accession>
    <name>A0A010YUV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">Cloev_1094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711194.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1165"/>
    <dbReference type="HOGENOM" id="CLU_132825_2_0_0"/>
    <dbReference type="OrthoDB" id="1965002at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="10489" checksum="048F18EACCBC0118" modified="2014-06-11" version="1">MKLKPLGDRIVVKAAPNEEKTKGGLVLPDTVKEKPVEGIVVAVGAGKVLDNGQRQPMEVKVDDKVIYSKYSGTEVKVDDENYLIIGERDVLAIIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUY9</accession>
    <name>A0A010YUY9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnc</name>
        <name evidence="10" type="ORF">Cloev_1131</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711269.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1204"/>
    <dbReference type="HOGENOM" id="CLU_000907_1_3_0"/>
    <dbReference type="OrthoDB" id="1890943at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="11"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="161"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="230" mass="25683" checksum="AEAA62552BD8D4CA" modified="2014-06-11" version="1">MKTDKGREELLRAFQKKLRYQFNDTELLQEALTHSSYANENGVKFNERLEFLGDAVLELVTSDKLFSSYPDYDEGQLTRLRARIVCKNSLSLWASEMGLKNLIRIGKSLVKSGPTDSVAADCVEALFGAIFLDGGFPNAVEAVSNFLDTKPEISGAAVIKDPKTELQEYFQRQGMDVPCYETMERTGPEHALNFKVRLAMGNKILAEAWGASTKEAEFKAAEEALKKIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGZ3</accession>
    <name>A0A010ZGZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalamin biosynthesis protein CbiK, Co2+ chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.112"/>
    <dbReference type="HOGENOM" id="CLU_036584_1_1_0"/>
    <dbReference type="OrthoDB" id="1100154at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016852">
        <property type="term" value="F:sirohydrochlorin cobaltochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019251">
        <property type="term" value="P:anaerobic cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010388">
        <property type="entry name" value="Anaerobic_Co-chelatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06180">
        <property type="entry name" value="CbiK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033579">
        <property type="entry name" value="Anaer_Co_chel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457917" evidence="3">
        <location>
            <begin position="31"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR033579-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR033579-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG77999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="305" mass="33511" checksum="845C597CD2A3C00C" modified="2014-06-11" version="1">MIERMEIFLMKSFVIALVMLTLVMSGTAFAAAPKDKPDKKGILVVAFGTSMPEAKKAIDNLVDSTKKAFPDTEVRLAYTSNIIRRKIAKEQNLNIPTPTSALAQMNDEGFTHVYVMPMHIIPGEEYDDIAGLVNGFAAVKGKYEFRDLKLGSPYLSSAADCDLMADILIKRFAKDLAKKNTVIVLMGHGTPHHAANAMYSQLQLSLDKKAPGRFALGTVEAAPMIEDVIARLKHDKSVKTLVLSPLMIVAGDHANNDLADKDDPESWYSQLKAAGYKDVRTFLVGLGEDADMARVYVSKIKDMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH84</accession>
    <name>A0A010ZH84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methionyl-tRNA formyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709290.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.201"/>
    <dbReference type="HOGENOM" id="CLU_033347_2_0_0"/>
    <dbReference type="OrthoDB" id="2009156at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="2">
        <location>
            <begin position="26"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="3">
        <location>
            <begin position="205"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="291" mass="32415" checksum="0B1834EF3B57F0A7" modified="2014-06-11" version="1">MTRPRTVIFAYSEVGCLCLEELIKDGANVAAVFTHEDDPHENIWFRSVKEIAEKNGIPVRTPKKLEADEIEYFNSLAPELVLSFYYRALIPKAVLDAPRLGAYNLHGALLPKYRGRACVNWAVLNGERETGATLHVMTEKADRGDIVDRQAVPIEFTDTAYDVFMKVAEAARQIVARRLPELEAGSAPRRPQDESAATCFGRRRPEDGKIDWSKSAEEIYNLIRAVTHPFPGAFTELAGKKYYIWKARPIEGGAKPHTIVSENPPVIGTGDGLLEILRLQPEGGEEGETLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH97</accession>
    <name>A0A010ZH97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ABC-type transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0194</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709301.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.213"/>
    <dbReference type="HOGENOM" id="CLU_040769_1_1_0"/>
    <dbReference type="OrthoDB" id="1215743at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="309" mass="32776" checksum="9F1E2685BF668572" modified="2014-06-11" version="1">MEFLTVVLAAAVRSGTPVLYASLGEVVSERAGVMNLGLEGIMLVGAYAGFAVTMATGDPWFGIAASFAAGCAITLIHAFLCITLMCNQVVSGLAMVLTGYGLSALMGRSAIGQTIQGMKQMNLPLLADIPFIGPIFFQHNAMVYLSYILVVFLCWFIFFTRPGLNLRAVGENPRAADAMGLSVTKLRYFYCVFGGGLAGVGGGYLSVVYAQMWIEGMTAGRGWIAVALVIFGLWNPARAALGAYLFGGVEALQLRLQAMGSTISTSLLMTLPYIMTIIVLTIVSVRAGKGRLLGAPAALGVPFRREDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHE3</accession>
    <name>A0A010ZHE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Altronate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709387.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.250"/>
    <dbReference type="HOGENOM" id="CLU_084161_3_0_0"/>
    <dbReference type="OrthoDB" id="1994547at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11613">
        <property type="entry name" value="SAF_AH_GD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044144">
        <property type="entry name" value="UxaA/GarD_SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="2">
        <location>
            <begin position="15"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="10452" checksum="C30455667385B611" modified="2014-06-11" version="1">MAQIKIDAILISIRDSVATVNRSVKRGEVLAYMNGGDLMEITADDDIPIYHKIALVSVPKGAPVFKYGEKIGRATRDIPAGAHVHSHNLTDIGEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHM4</accession>
    <name>A0A010ZHM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FMN-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484804.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034450_0_0_0"/>
    <dbReference type="OrthoDB" id="396650at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458163" evidence="2">
        <location>
            <begin position="25"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="3">
        <location>
            <begin position="66"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="385" mass="41469" checksum="4F9AB432A3EE8697" modified="2014-06-11" version="1">MKIKFNRIAFLAAALLLIAAAAFNRDGKLLGVAPGDQKGGGTRTEWTAEDGSRVISTEGLAKDILGFGGGIPLHIYMKEGRVVRVEAQDNYETPPFFAQVESNILSAWNGLTAEEALNKEVAAVSGATISSNAVIGTFRRGMEYARGTAAEAPREGSRPGAGALAALAVALCGLFLPLFIRSPKYRPLQLLANTAVLGFWSGTFISLSLLTGFAANGVRSWNAAPALALLFAAFIMPLFGKKGHYCSWICPLGSLQELLGRIPVPKAKLPADAIKWLGRLREAVWMAMMLLMWLGVGFELMDYELFSAFLFRRAAWPVLVLAGVFFALSLVTPRPYCRFLCPTGTLIKFAQGDSSVCAASAPRALKLTMSAIFFVSSIMTLFRMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHU6</accession>
    <name>A0A010ZHU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441555.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.400"/>
    <dbReference type="HOGENOM" id="CLU_053110_1_0_0"/>
    <dbReference type="OrthoDB" id="678795at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIDA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA" evidence="1">
        <location>
            <begin position="276"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="429" mass="45514" checksum="28D60E5761CCE019" modified="2014-06-11" version="1">MSKIKIVVVGGGWGGCAAAIAAVKAGAEAVLLERTDMLLGTGLVGGIYRNNGRQTAAEEMTTLGGGDLFHVMDECAGHKNIEFPGHAHASLYNVYEIEPAVRKCLAGLGVKVVANASVVKIDKKEGKVLSVVTRDGAVYEADAFVDATGTSAVPGNCVKYGNGCAMCILRCHSFAPRVSICTLAGIEEWNGRKKDGSLGAMSGSCKLFKESLSENIVRKLNDTGVCVVPIPAAANMSEKLGMKACQQYATKDFAENIILLDTGPAKLMTPYFPLEKLRLVPGFEKARYEDPIAGGRGNSMRYFQFANCAHSLQARGEVDNIFCAGEKGGAMVGHTEAVVTGTLAGNNAVRLAAGKELVELPNGLAVGDFINHVTDEMKRDECRGTKYTFSGSVYFERMKELGLYVCDPSETAKKVEAAGLSGLFARKIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHW3</accession>
    <name>A0A010ZHW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BIG2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441593.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.431"/>
    <dbReference type="HOGENOM" id="CLU_363982_0_0_0"/>
    <dbReference type="OrthoDB" id="633672at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045829">
        <property type="entry name" value="PKD_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19408">
        <property type="entry name" value="PKD_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459100" description="BIG2 domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="442"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="767" mass="79055" checksum="B7E0E4FFB3BD2FD0" modified="2014-06-11" version="1">MKKSYSNKLYLLALALLLAFSALSPAAAAEFWKTDTSWYDGPAAAKGTVDDPYRIADAEGLAGFAALVNAGSDDFKDKYVTLTLDVDLAKKEWIPIGWMVAYGNLRGFAGHFDGGGHKITGMLISTGEYMPKGTGSKIDKNGTISNTTGLFGYLAATGTIQNVYVEGSVTNKVSSGAAGLVGWTDGYVYNCIVSCDLDASGQGNAYAGVVASLIGGGKVRNCVTYGSIKSSVGAAYSGGIAGFGYWYRGATENCVAMCSSIVSMADAGGIWGGFNSTTKYCVSTSDYVMGGQPNYTGGIVGAYGYGYTECYWLYAKEGQPEFGWGGSKTEGRVTDPALLPIASVVLTPDSFKTLKTGETRVIEAAAYPPTGDASALKYNWTVADGLTIVSGAGTSKITVRADKEGFYPVSASVTGILGVDAASTDIAVTPGGLLKVTSKTITVSEINISGNAEALTEGESRLFTAACKPSDAENQRVKWTISAASGGAQDSDIALVENADGSATVTLRRAGTTAAGYTLTATAEDGGASASVTITTSVIEGEEISSILPVGGVVTAETEAVKANGINSSQLATLVKTLGASMSSFKVNGNGVVYLEDSVAQKAIVNAISDDKVVLEKAVLLPLFKTQVSAAGATAVTAFIISGDKLMADTPQEVKLVKTRPDGTGTFLTYAAAAADYTDGHFTIQNMDDSVLAADGAIEASKSYKLVVYVKDGGAYDIDPTECSIVDPLALIKTSQKQSSSSGGCNGGFAVLALLAALPLLRRRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHY9</accession>
    <name>A0A010ZHY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lactate dehydrogenase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441634.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.469"/>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_0"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="17"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="114"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="318" mass="34309" checksum="13ED27DFD4E37CE1" modified="2014-06-11" version="1">MAKYKVIVTARSFGKTDSKARELLEEDGCSVIKLEEAGGPIYEQLKNELPDADAVIAGLDDYDERLLARGGKLKVISRYGVGYDRVDVGAASKFGIKVTVTPGANGDSVADLAVGLMLAAARNIPLMDAAMRAEAQKRPQGVEMFEKTLGVVGAGRIGQGVARRCRGFGMKILCYDVYQNEAFKDECRAEYVSFERLIRESDFITIHSPLTEETKNMFGEREFAVMKRDAIIVNTARGGIIDERALCAALRGGVIRGAALDATVSEPPYGEEILTLPNCIVTPHAGAATKEASAKMSLMSARNVLDVLTTGECKYAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI19</accession>
    <name>A0A010ZI19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional activator, adenine-specific DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484832.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1092833_0_0_0"/>
    <dbReference type="OrthoDB" id="1487464at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090304">
        <property type="term" value="P:nucleic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="254" mass="29181" checksum="6AACB3AA770141D2" modified="2014-06-11" version="1">MDVTLERSTCELYRTIYADPPWMERGGGKIKRGADRHYALMKTTEIASFLHDTGLESFIAPNAHLYLWVTNNFLTDGFRVMDAWGFSFKTVITWCKEGNIGLGQYFRGRTEHCLFGVRGMLPYKVKDGKRQQGVTGFTAPRGKHSEKPLFMRRMVEKVSYPPYLELFARQRFEGWDCYGTKEWCEMRCVDDCEFCAGIDWSGRSPAVECTCSGCEGRSIDPFAYCYFGKKRSVEEVRPVDPRQSSLFDSQGALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIH1</accession>
    <name>A0A010ZIH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710375.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136765_1_0_0"/>
    <dbReference type="OrthoDB" id="2000842at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012427">
        <property type="entry name" value="DUF1622"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38468">
        <property type="entry name" value="PTHR38468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07784">
        <property type="entry name" value="DUF1622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="123" mass="13709" checksum="9A5727023DF51C49" modified="2014-06-11" version="1">MLHDFAAISRTIIEFISILIIMCGVVVAIFRGCRLFFAMRSGSSLPRDAWIQLRLSFEDTLMLGLQFLMAADIIGTISDPDLQGVIVLSVIVLLRVILSFTLSREVAEMDRQKRESAAAPHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIM1</accession>
    <name>A0A010ZIM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="10" type="ORF">Cloev_0676</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710463.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.721"/>
    <dbReference type="HOGENOM" id="CLU_108412_0_0_0"/>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="50"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="158" mass="18172" checksum="2607736ADB944D23" modified="2014-06-11" version="1">MRCPVCGAPETRVIETRSSDEGRVNRRRRECPECQSRFTTYERLEEKSYLWVVKKDGRREAFDRDKLIRGFQHACEKLPVALDVLEAAAARIEERVRASGQGEVSTTRLGEMAAEELRGINKVAYVRFASVYREFTDVSSFTNEIARLLDDKEAHRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ32</accession>
    <name>A0A010ZJ32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arabinose efflux permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442036.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059146_0_0_0"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="43542" checksum="9F572774D87F7494" modified="2014-06-11" version="1">MNETKRILSPELGYIFIFFSITFISASMESGYYFLLPYLEGRGVAIGALGGVAMGICYGVSFFIRPFVPLFEQRFGDDKMLWGGYACFFMSAAGLALFSDAIGSIIVWRGISGLGLSMVGVSLTAYERRFIPEKIRGRSIALITTAYSLPSLIIVPAMEFLITRELYRCYIFFFPLLIALGTIAIRRLPKAGVGENAEAEEKDDARLSYTALLKKPQIILFAASAALFALTDAGQLTFVQLAGELGLAASYFFSVSAATALLFRILCGKLIDLLPRKICAAGATSVTAAMMLTMTAVSSPLALMLCGFLFGIGMGFGYPAFMCLILDLGGKRYVTRLAVVFGLIYSGFFFLTPVIMEFFIGITGSAALAYRIIYGSVLLATAVIVPASAKVYRKTNTIQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJQ0</accession>
    <name>A0A010ZJQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442326.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1100"/>
    <dbReference type="HOGENOM" id="CLU_012893_0_2_0"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="441" mass="46392" checksum="58EB995C5957808A" modified="2014-06-11" version="1">MKNSREFFSCVLPSLAAFALSGVYAVVDGFFVGNSIGDAGLAAINFAFPVTALLQAAGTGIGMGGAIRFAICAAQGDEKTARHYFSATLILLALCGALLSVLFFVSAGPLLKTLGARGATLPLGREYLIFIAAGALFQVFGTGLVPLIRNMGGSLYAMFAMSAGFIANIILDWLFIMVFGWGMAGAAVATVIGQAATALCAAFYFAVKRYPPSRPPVRMVLRLFSVILKIAISPFGITFSPMIGMMLMNRFSVLYGGEGAVACYACVGYIVTIVYLLLQGVGDGCQPLISRYYGSGRRADMRRVCLLAYMTAGALSLLSICALYLARGGVGELFGASEAVGRSVARVLPLFLAGVSFLAFTRITAASFYATEESRLSYILVYAEPLFLLAFLLLMPRFFGLTGVWLATPASQAATAAIASAARRKAKALNPSRAGRAEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJU0</accession>
    <name>A0A010ZJU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_1079</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442371.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1148"/>
    <dbReference type="HOGENOM" id="CLU_007884_10_2_0"/>
    <dbReference type="OrthoDB" id="282830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="7">
        <location>
            <begin position="7"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="8">
        <location>
            <begin position="276"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="363" mass="40062" checksum="05B3828625A488FC" modified="2014-06-11" version="1">MEHKTALYDRHVELGGKMVPFAGYMLPVQFKKGILEEHMIVREHVGMFDCSHMGEARLDGPDALKNVNNLFSNSFDSMKDGSCRYSIMLYEDGGCIDDLIVYRRSQDSYYVIINASNAAKDVGWIRDHLIGDVKLTDMCDGYSQIAVQGPEALKMNSIISGSPLPEKYYTFTEHVIIAGVDCFISRTGYTGSFGYELFMPNEGAVAVWNALLEIGVEPCGLGSRDTLRTEAALPLYGHEITEVIDPLTAGLNFAVKMDKPDFIGKSGLVKRGTPTKKRVGIKVVGRGVIRDHQDVYDGDKLVGFVSSGTFMAWINASAGMAFVEPDVAVEGKRLEVDVRGRRVPVEVVPLPFYNTAREVPVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJV9</accession>
    <name>A0A010ZJV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711207.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_0"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="306" mass="34844" checksum="1E24B0474A6ADA7E" modified="2014-06-11" version="1">MTLHHLRIFIAVAESGRMSAAARDHHLSQPTVSQIIRELEEYYSAALFERLSKRLHITEEGKRLLGYAREVISAYENLEYNMSPAVRRDTLRVGSSVTVGMCVMPAVVRKFSETRPDTDIYSYVNNTRTIEEMLLRSELDAAVVEGKIRNPDLLRFHLMDDYVALFCAKDHPFAGKKYVSLDELCRENFVMREHGSGTREIFENFIVEHKRKLKIKWEVACFDSTLRAVREEGCIGVASIRLLIPHLDAGGIRAICSGSGDWDRVFSLVYHKNKYMTEAMEAFIGTARGIKDAPLPDRGRMARLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKX7</accession>
    <name>A0A010ZKX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Desulfoferrodoxin ferrous iron-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the desulfoferrodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708502.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.8"/>
    <dbReference type="HOGENOM" id="CLU_118960_2_1_0"/>
    <dbReference type="OrthoDB" id="1496450at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002742">
        <property type="entry name" value="Desulfoferrodoxin_Fe-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036073">
        <property type="entry name" value="Desulfoferrodoxin_Fe-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01880">
        <property type="entry name" value="Desulfoferrodox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49367">
        <property type="entry name" value="SSF49367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00332">
        <property type="entry name" value="neela_ferrous"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Desulfoferrodox" evidence="6">
        <location>
            <begin position="11"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG77912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="131" mass="14517" checksum="5ADCDFE41CD1D5B8" modified="2014-06-11" version="1">MKIGEVMRDGDFKAEKHVPTIEAPEKVKLGEEALVKVMVGQEIKHPNTPLHHIRWIQLYFKPDDATPVIEVAKFDYSAHSDTMNPDMPGCAAADPASCVKVKLTKSGTFIAVSYCNIHGLWESAKKIEVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL02</accession>
    <name>A0A010ZL02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708558.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035605_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="313" mass="34115" checksum="519B43A63E51F134" modified="2014-06-11" version="1">MGGKKTELLQFQTEEGRKFELPVALVIGDAEGPDAVVTAGIHGGEFCGVLAAVKLFRELSPSDVKGSVKIITVCDTSAFESRRVSLSPLGGDNLNRNFPGRTKGDHRDMLAAKIFDEIKGADYHMDLHCGEVLERSAPFAIYHRGRKGDLNDRSHEMAYYYGLPNIMITETDGRWSDKGTCYASVYENIGIPSVLFQTGGLGIASADNVNTHTEGIKNVMRRFGSLRGSVQPVGRPQIFENMELVCTKGSGIHYRRVNVGDAVKRGQMIGMLTDYFGTPTEKILSPIDGKVLFISESSAMSERDFVAAIGVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL77</accession>
    <name>A0A010ZL77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, B subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441314.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.136"/>
    <dbReference type="HOGENOM" id="CLU_019942_4_1_0"/>
    <dbReference type="OrthoDB" id="1380130at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="227" mass="24431" checksum="78134EE67AC028D4" modified="2014-06-11" version="1">MFTFTEEEAKARIAKYIAREFDEMSEEHDLFVNLGVGIPTMVADYTASKRVFLQAENGMLGVGPVADEAHIDPLLINAGRAKVTETTGCSYMDSADSFGMIRGGHVDATVIGAFEVDEEGNVANWIIPNGKMLGVGGAMDLVSGAKKVYIAMQHVSKKGKSKLVHACSLPITGYSAVDTVVTEYAVFKFENGQMVLTAKAKEVSFDELKSVTEANYSVAPDLIDMAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL93</accession>
    <name>A0A010ZL93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hydro-lyase, Fe-S type, tartrate/fumarate subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709234.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041245_0_0_0"/>
    <dbReference type="OrthoDB" id="843731at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="286" mass="30792" checksum="A84632DA7F2C9DD4" modified="2014-06-11" version="1">MIDCREVTEKTADTLVRASTVFRPDQIAAYKRAAENEESPHARWVLNNILENAEIAESKVFPLCDDTGIPHLFLEVGEECVVPAGFYKAVEEGVAKGLRTLPGRPMAVMGNDAERISQSGGLSDDSGALAMAPIQTRHVPGKDIRLTVMMYGGGPEIRGKTLRVFHKHSVDTVIDEMIAWGAEGAKLLGCLPCVLVFGIGRSNYEAASLGMEAMAKGNFLVQSEMEKRITDAVNESGYGALGLGGKTTVLGTFVKVGPQRASGIRVVSMRLGCCFDPRRAECLFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL96</accession>
    <name>A0A010ZL96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484770.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076298_0_0_0"/>
    <dbReference type="OrthoDB" id="1394056at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="295" mass="31099" checksum="CA100FBC2EDC59AB" modified="2014-06-11" version="1">MNFQKYNVIQEGLVYIDHGPITMTLEARRNGCAFTEAAVAGAERVLEVFGESAVYLEYLRRPVEKISSLPDGTPLAVRKMTESVMMLEEGDFTPLAAVAGTTADFAVEAMAAHGADYALANNGGDIAWHISRGQSTPRDFLKVGLISDINGGRATHSLKIKSFGEIRGLATSGLGGRSLTRGIASAVTALAPDSSRADAAATAIANACYCDDPAIEQCLAEELDYGTDIRGLTVTKSVGCLRSGSAELALEAGCRRAETLIGKGMIFGAVLFVAGAMQIVKTKERVDLFEVAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLC1</accession>
    <name>A0A010ZLC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid/polyamine/organocation transporter, APC superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441358.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.185"/>
    <dbReference type="HOGENOM" id="CLU_020854_4_1_0"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022520">
        <property type="entry name" value="Glu/GABA_antiporter_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03813">
        <property type="entry name" value="put_Glu_GABA_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="501" mass="53797" checksum="DACA5179FC12E868" modified="2014-06-11" version="1">MSAENKPASGSKRGTIGVFTLAMMNVAAIVSLRGLPAEAEYGLSSVFYYIFAAVFFLIPVALAAAEMATAWPQKGGVFRWVGEAFGGRLGFVAIFLQWMQNTIWFPTVLTFAAVSVAYIGTNPGADSALAANKMYTLAIVLVFYWGSTLMNFRGMSLSGAISKWGTLIGTVIPAAILIVLGILYYVTGHPIYMSLHAGDLIPDLGNFSNLSLAVSIFLFYAGMEVSAVHVNEVENPEKNYPLAILISAGITVAIFVFGTLAIGFVIPQKDINLTQSLLVAYRNLFQAFGLEWLSPVVAICLALGVFAGVNTWIAGPSKGILAVGKAGYLPLILQKTNKHGVQVNILYFQSAIVTVLSVIFVLLPSVQAAYQILSALTVTMYLIMYMLMFGAFIKLRLKEPNTPRPFKVPGGELGMWLVGGVGLIGAFAAFIVGFIPPGQIPVGSPTEWVGLLIVGNLLAVGVPLLIYHSRKESWKTAEGADSFEPFSWQKKPDAPAQTKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLC6</accession>
    <name>A0A010ZLC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0177</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484780.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.194"/>
    <dbReference type="HOGENOM" id="CLU_000445_114_9_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457977" evidence="6">
        <location>
            <begin position="30"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="576"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="813"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="954"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="867"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1084" mass="119323" checksum="6AD564D46A0E7AEC" modified="2014-06-11" version="1">MRERRQTAGLVAGVIICFLLILCASPCAAAAHGQDLRTVRVGFFAFDGYHVTSGDGARSGYGYDLLQHMAGYTDWRYEYVGYGKGWGEMQRMLEKGEIDLLTSAQNTAERRKRFDFSDRPVGTSAAILTVKAGDKKFALKDYANWNGMRVGMIRRNSRNDDLAGFAAQKGFSYSTVYFDDTASMVKSLKTGGEIDAALTSNLRSIDDEWVLAQFASSPFYIMTRKGNRRLMAEVNEALEQLSNDEPELLTMLMNKYYTPDCGEEIAFTVEERAYIEAMRGVKLTALINPDRAPFSSFENGRPVGIISDIARMITERSGLNIQLIETGSREEYRRLAKSGKTDIRFDARYDYAEAEAMGCRLTAPYLDASVTRLYKRGGDGFSSAALLKDSDISAKYGEYLSDKRRDAVYYDTVAGAVGAVLSGKQSVTYLYRRSAELAAQNDETNRLMIEDLYGYNTSFAVAVSGRQSHLLFSILNKSVLSIKNEEIKAIDQRHASYTEKPFSFVGFIYGSPLVVSGIVAALFIMLGLAAFSVLLSRKRRREHAQLAEEKRRSGLLADALAAGERADAAKSQFLSRVSHEMRTPLNAIIGFITLARGAEPRQLEGYLTNTEVASKQLLLVINDVLDMSSIESGKMKIAHAPFDFRHMIHSVTSLYLAQCHQKGLLYETKLLTPVDDWFIGDQLRVNQILMNLLSNAVKFTTEGHVWLKISQRDASGNKAFIRIEVSDTGCGITKEMQARLFKPFEQESAAVAQKYGGSGLGLSIVKSLVSMMDGAICVESVSGKGTAFVVDLPFIKGEALLDAQMPAGIEKLRVLAVDDEPAEREYISVVLGRIGVRYACVGDGKAAIAELERCAGEDAPYNICLIDWKIPNMDGIEITKRIREKFNRNVIIIVVSAYEHNQAGESAVEAGANMFIPKPLFQSSLFDLFMTLTGGGVAGKKAAPAAPRDFSGKRVLLAEDNAMNRMVAEGLLGKFGLECDSVMDGRMAVDKFLASAPGYYDAILMDIQMPHMNGYEAARAIRCSAHPEAKTIQIIALTADAFNEDITKTLSNGMNGHVAKPIEPDVLAEALDTAFKAEQTRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLX9</accession>
    <name>A0A010ZLX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709027.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.384"/>
    <dbReference type="HOGENOM" id="CLU_130332_2_3_0"/>
    <dbReference type="OrthoDB" id="1868412at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="91" mass="10287" checksum="47480E466BE74262" modified="2014-06-11" version="1">MKECIESKNLHLRLRKVAGQVNAIERMIGEDVPCEDILIQINAAKNALHKIGQVILEGHLKHCVRRGIEQGDAEKTIADFVKTLEHFSRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM54</accession>
    <name>A0A010ZM54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pentulose/hexulose kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441629.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.467"/>
    <dbReference type="HOGENOM" id="CLU_009281_3_2_0"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="3"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="248"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="477" mass="52793" checksum="8F70EEE63579F987" modified="2014-06-11" version="1">MLILVLEASTTSAKAMLYNSDTHESKVLVKTYGKMYDDVTIHKAEQVFMEMAALGKELAQWQDVSVVSLSGTWHSILLCDKNMTPKTPVYLWSHTGAADICRGIRKDAAFVDSYYHKTGCMVNAIYPAYKLLMLRDRGYDLGGYYIMGQGSYNTYRLTGCRVITECLASGTGLLNIHEKRFERSILGEIGVGEDQLSELVSYSKTFPLSDEGAALLGIKAGIPVIPCNSDGGLNQVGVGALEEGVMTFSIGTSGAMRLTTPQALIPDVPSTWCYLSPKSWLSGAATSGCCNCIDWFRNSLLETRGSYAELDGEADAGADTPVFLPFLFGERCPGWDDERRGGFSDITPQMGRRDLYRGVQEGVLYNLYQCYQHLVKLNGKPKKIKLSGGILHSQNWTQMCADIFQEEMEIDKEKQGSLIGGAVLAMELLGVIGDAKDYRPEACERIKPDFQNAQLYAKKYRRYLDVYNENFCKGGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM92</accession>
    <name>A0A010ZM92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441713.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2536666_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="83" mass="8683" checksum="A5321DA29434EC6A" modified="2014-06-11" version="1">MTWPYEQEWLDYKAAAANVVVSETAFTSGTTKTTDAGFEDCKVGTLLITNVTASGGAATTTVYVVTAVAEDKIITGKQISNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMB0</accession>
    <name>A0A010ZMB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNF2 family protein,Eco57I restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.537"/>
    <dbReference type="HOGENOM" id="CLU_223764_0_0_0"/>
    <dbReference type="OrthoDB" id="47632at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040561">
        <property type="entry name" value="LPD38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041131">
        <property type="entry name" value="MuF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18857">
        <property type="entry name" value="LPD38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18819">
        <property type="entry name" value="MuF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="1936"/>
            <end position="2202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="847"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2737"/>
            <end position="2759"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3611"/>
            <end position="3638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="732"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="890"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="943"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2737"/>
            <end position="2753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="4346" mass="479286" checksum="319BC684E7BCB576" modified="2014-06-11" version="1">[encoded data, 4346 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMC9</accession>
    <name>A0A010ZMC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709629.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.558"/>
    <dbReference type="HOGENOM" id="CLU_029381_0_2_0"/>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="7"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="346" mass="37305" checksum="A5EA5BAB9F841202" modified="2014-06-11" version="1">MYHKIMDFRSDTVTKPSEEMRRAIAGAEVGDDIYGDDPSANALCKYAAEITGKEDALFACSGTMGNLLAFTTVGRHGESLLAGKRSHVWCAEVGGFSAVAGLCPYPLGDDDGIPDPAELAVASRADNDIHHPDTTILALENTHNYTGGIAVPPERFALTAREGRRLGFHVHLDGARIFNAAVRHGVDVRKYADEVDSVQFCLSKGLGAPLGSMLCGSRELIEGAKKWRKRLGGAQRQVGIAAAAGLYALKNNVARLAEDHANAALLVDMLKRGGVEVEERPNMTNMVFFPLKEGQVSDAEFEARCLEKGLLAHMISPRRARFVTHLDVGREDVERAAAIILEVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMI4</accession>
    <name>A0A010ZMI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441831.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.625"/>
    <dbReference type="HOGENOM" id="CLU_035307_0_0_0"/>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="501" mass="54250" checksum="62116A2809BBDE76" modified="2014-06-11" version="1">MAQNRTRWIPDTYIIIFFVVLFAALLTWAVPVGKFETHEIKYTMGSTEKSRNVLVPESFRYELDKEGKPIVKGVRLFEPYGETGILNYAFEGLVSGDKWGSAVGVVAFILIVGGAFGIVLRTGAVESGMKRMIKKTKGMDTLIIPVLFFLFSLGGAVFGMGEEAIPFVFIVVPVVIALGYDSIVAVMITYCATQIGFGASWMNPFSVAIAQGIAQIPVLSGSGFRLFMWFFFTLLGTLYTWRYAVKIRKNPDLSPVRASDQYFRDELAAAGDTDEKFGTGDILVILTIALGMVWTIWGVVEKGYYIPEIASQFFVMGLVSGVIGVVFKLNGMKVNDIAVSFRAGASDLLGAAIVVGMAKGIILVLGGDSPTEPTVLNTVLHNVGLMISGLSPVISAWLMYLFQSIFNFFVVSGSGQAALTMPLMAPLADIAGVTRQVAVLAFQLGDGFTNLIVPTSAVMMASIGAARIDWATWAKWQIKFQGVLFLFGSIFVIAAVMIGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMJ9</accession>
    <name>A0A010ZMJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol dehydrogenase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441856.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.647"/>
    <dbReference type="HOGENOM" id="CLU_044754_1_0_0"/>
    <dbReference type="OrthoDB" id="717704at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe-ADH" evidence="7">
        <location>
            <begin position="8"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="369" mass="40001" checksum="990CC99120CC7E8D" modified="2014-06-11" version="1">MLKMFISPGRYVQGAGAVKELGRHISVLRCKNALLVVDPIGIKAVGEGIYKSLENMDITCHTEEFRRECCQEEIDRIAESAKKYASDIVVAVGGGKTIDIAKAVSYKMETKLAVIPTIAATDAPCSALSVIYTKDGVFESFLVLPKNPDLVLVDTEVITKAPVRLFVSGMGDALSTWFEADTSFKSCTCGMQQTLSTLAAQSLARTCYETIITNGYEAKLAVERGVVTEAVERVTEANTLLSGLGFESGGLAAAHSFQDGVTVLEETHKYFHGEKVSFGVIFQLVLENRPEKEINEVLDFCLKVGLPVSLEDIGVVDIDKPRLWKVAVATAGPEETIHSEPFEVTPEKVFAALLVANALGKEAKNKFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMK4</accession>
    <name>A0A010ZMK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EAL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441863.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_50_0"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="65"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="202"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="453" mass="50792" checksum="B144BB45FE0AFDC4" modified="2014-06-11" version="1">MPADVLMLALILLAVMVIALTFASITKSRSMKRIKDLLYNDQLTGALSQAGFERGLRKRAASDADSLYIIDFDVYKFQIYNETFGREEGDLLLLEIAAVYRRYFADGGLLARIYADHFAALALCGGIDELRERIVSMTDELKRSLKERSIIVNYGIYPIDDRKMPADMMMDYAAAAKLTVKGNSEKYIGVFDGRIYKKLRENSELISGFDAAAAHGEFIPYIQAKYDGESGRISGGEALVRWKCPDGRIIPPARFISLFEKSGQITRLDFIILEQVCLLLRSVIDAGLTALPISVNFSRLHLHDADFVAKIREAAAKYDIPSRLIEIECTESVVAEDLNTIRQVFSELKKEGFSIALDDFGSGYSSLNTLISIPMDVIKLDRGFLLQRETDRASSEEVVETIISLAHKLSFKVVAEGVESRDQLDFLRRAGCDTIQGYYYARPVPPEEFVKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMK7</accession>
    <name>A0A010ZMK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Citrate lyase, gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158489_2_0_0"/>
    <dbReference type="OrthoDB" id="1966288at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023439">
        <property type="entry name" value="Mal_deCO2ase/Cit_lyase_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06857">
        <property type="entry name" value="ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="90" mass="9898" checksum="50484015A424A3B0" modified="2014-06-11" version="1">MQLFHTAHAGTLESSDCLVTVAPGEGFALDYRGANSVIFAKRTELLVRGMLEKHSLKEARVTIQDQGAIEITIMARLETALLRAAKEETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMX5</accession>
    <name>A0A010ZMX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710606.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239667_0_0_0"/>
    <dbReference type="OrthoDB" id="1589784at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="223" mass="25255" checksum="C5BD17DBCB07FB21" modified="2014-06-11" version="1">MINSVLPYWDQNIDLDIAPWVPYGKDYSPVTVNRLYDPLLGSLAGLALEMKSEFLYLRSFQSGNIGTMARQNMIDPGRNGGIELGFTMVFSYSEMLEHSVLPLLRQYPGLMAGLTLCDIWSENVLVDECKVLLLVNEDPFFNEGAFMESLYKSFQVFAGRENSNLSFFAEKFGYRRFSISYETDNLTQMRITQALFDMELDATKDVLGPVPELKIPPLPSIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN20</accession>
    <name>A0A010ZN20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethanolamine utilization protein, putative chaperonin protecting lyase from inhibition</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442020.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.817"/>
    <dbReference type="HOGENOM" id="CLU_046255_0_0_0"/>
    <dbReference type="OrthoDB" id="845924at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009377">
        <property type="entry name" value="EutA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06277">
        <property type="entry name" value="EutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012293">
        <property type="entry name" value="EutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="478" mass="50930" checksum="5ACFDF82544CB44B" modified="2014-06-11" version="1">MGGETITSVGIDVGTSTTQLIFSRIKIENRASSYTAPRISIVGKEVFYRSPIYFTPLLSSTEIDAEAVKRIVTEEYKRAGMTPAMVNTGAIIITGDTARKKNANQLLSALSALSGDFVVATAGPDLESVLSARGAGTDKISEDNRAVVANLDVGGGTSNIALYEKGSLRGVTCLDIGGRLVKVENDFITYVYPKIEKIAADNGLAVKAGERADAERLRSLCRLMAGYLAEAVGLLPRSESCRYLYTNDGKGLPEGLPAITGVTFSGGVADFVYSPSQGDLFRFGDIGVILGDEIRKQPAFSQVKLYTPAETIRATVVGAGTCATEISGSTIAYTPGILPIQNIPILRVPDEDEATPERVERSIKFQLPLFMPEGRQEQIAISLSGDRYKSFSAVQRLAEAVISGARTLIDGPFPLIVVVETDIGKALGHALNVKLDHKKPVICIDGIHSASGDYIDLGEPVFGGHVLPVVIKTLIFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN75</accession>
    <name>A0A010ZN75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484874.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.861"/>
    <dbReference type="HOGENOM" id="CLU_024867_1_2_0"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="500" mass="54492" checksum="97378AC70BEE0330" modified="2014-06-11" version="1">MEATVAKQVEAALEYIAWTVLWNKYFAVMFLLLGLYLTIGTRFFQFRRFGDIFYNTLGGLFRKKGPNVPDSKVTSFGAFATALGGTVGNGNIAGVASAIAIGGPGALFWMWMAAIVGMITKMSEIVLAQQYKQRYEDGTSYGSAAFYIHKALVEGKGWKWCKILSMLFTVTMIGSFYFAPGPYTIVEALQSAFKLPGSVAIMCAVAYTGVCYVIVLGGIPRIVKFAERAVPTMVLCYLAAGIFIIIKDIPATAAAIKSIFYYAFQPYAAVGGFAGVTVMKVVQVGVARSVYSNEAGWGSSPIIHAAVDVDHPGRQGLWGAMEVFMDTMVVCTITGLMVIITGAWQTGRGGAGSVGEALGIVFGGYAPHALAFFMIIFSLTTTTGWFSYLESIIVYCVSDKTHEQRMKYVKFVRYTGPMVPLCVSMFFFYHGTVPSIVWMMLDIQSALPVYVNVIALTLLSPVIFKLVREFEDKFLDPEKAARKALALNKAKNTAEEDAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNK4</accession>
    <name>A0A010ZNK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRAP transporter solute receptor, TAXI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442225.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1017"/>
    <dbReference type="HOGENOM" id="CLU_033215_4_1_0"/>
    <dbReference type="OrthoDB" id="991310at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458028" evidence="1">
        <location>
            <begin position="24"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="315" mass="33299" checksum="BFF0AF1FC570066D" modified="2014-06-11" version="1">MKNFIRLALVTALIASFAASASAATFINIGTGSTGGTYYPVGAAMAKVWNSSISGMKANAQSTGGTAQNLALLGKGEAEVIFADGLYFFAYGGKGAFEGKAMKNLRGLVPLYAEPIHFLVAKGSNIKSIKDLKGKRVSVGAVGSGTEVTVRTLLKANGIDPDKDIKAENLGLSDTASAFADKNIDAGLTVGALGIAGVVEIATLGTAELRDFEPEAIKKLCAELPYYLPFDIPANTYKGQTKPVKAMASWNVLITNDKLDAETAYQMTKALYEKKQDILNVSTRLASMSPENLKYIQVPIHPGALKYYKEIGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNV8</accession>
    <name>A0A010ZNV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dihydroorotase, multifunctional complex type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711164.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1134"/>
    <dbReference type="HOGENOM" id="CLU_015572_1_0_0"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="52"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="434" mass="47278" checksum="9D44E70C0DE40355" modified="2014-06-11" version="1">MEKFLFKDFKIFNGKEFIKEDCLLVEDGKVAGLGRDLACEGAEVVEGGGRLLTPGFIDLHAHFRDPGGEWNEDLNSGAHAGAAGGFTTLVAMPNTKPAVSEPALIEYVVSHGAAAKASRILPAGCVSKNREGKEICEMEKMTEAGAVFFTDDGAPVATSQLLRLALLYTGKKLPRVMEHPEEISLFKGGQVHEGRVSAMSGLKGIPGASEEIDVARGIALVRDTGGRIHFTHLSSAGAVELIRNAKRAGLDVTCDTTFHHLTLNENAVINSGYNSRFKVNPPLRSADDQRALWEGIKDGTIDAIVTDHAPWHMDEKDEPFQEAPFGIASLECAVAVLLDYRSRNYPDVPLELLFAKMTSAPASLLPEKWQGLGRIEAGAPADLTVIDEDRTRIVDCRTWKSKARCCPWEGVALTGWPVMTFVEGRRIWQDEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNY3</accession>
    <name>A0A010ZNY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Type II secretory pathway, component PulF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cloev_1099</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711203.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035032_2_1_0"/>
    <dbReference type="OrthoDB" id="1268170at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001992">
        <property type="entry name" value="T2SS_GspF/T4SS_PilC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00874">
        <property type="entry name" value="T2SP_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="11">
        <location>
            <begin position="81"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="11">
        <location>
            <begin position="286"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="415" mass="46087" checksum="BA514AADA9493100" modified="2014-06-11" version="1">MEFYYEAKDKSGKTVSGTRNEPGEPEVLSWIRGNGWVPLNVSQQLEISLSAPGDKLAADPKGKSEFWDLSPRIKLRDKLIFFRQLSTMIAAGIPVTSSLAILVDQTQNRRFRRVLTRVYKRVSAGTTLGSALAENPKCFDAITIPLVRSGEESGTLDMSLAKIASFMDDQDNLRKKIISAMTYPAVVIGIALLVLGVMVAVVIPQFEKAFSNLNIKLPALTLMTFKFGRWMEHNWYIIPLAVVAIVLLFSQLRKMKSMKLPLDSFMLRIPVFGDIAFKASLTRSFRTMGSLLRSGVPVLSALEMTADVAGNEKIKRGFLEMRDGAAMGRALNDVVREKKLFPPMIGHMIAVGEETGRTDEMLEKVADWYDAELSEKIKRLSSILEPVMVVFVGVIVGFMVLAIFLPIISAIQAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A782</accession>
    <name>A0A011A782_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708501.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1515349_0_0_0"/>
    <dbReference type="OrthoDB" id="1905150at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="177" mass="19629" checksum="F51FF40ABDE45623" modified="2014-06-11" version="1">MKKVDGARAAGDIFREVTKSGGRPAADSERWAQLSLSVKLAELEERWEEIAGSPLAQKSQLAVCEFAGEVMTLTVNVSEQSILSAVRFRRAQVEKRLAAFFGCKKIKVDFRVGPVIRHSQAQPPLPSYKRRAPVVLSEEDVEAEKRDFEESGLSGELALRMARVKLSLEKLSRRSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7E2</accession>
    <name>A0A011A7E2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Pyruvate:ferredoxin (Flavodoxin) oxidoreductase, homodimeric</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0070</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441249.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.84"/>
    <dbReference type="HOGENOM" id="CLU_002569_0_0_0"/>
    <dbReference type="OrthoDB" id="10483at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037112">
        <property type="entry name" value="Pyrv-flavodox_OxR_EKR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000159">
        <property type="entry name" value="NifJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="678"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="734"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="968"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="997"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="697"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="743"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="746"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="749"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="753"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="821"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="823"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="846"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1077"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG77971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1177" mass="129306" checksum="AD00B43CB506FDBE" modified="2014-06-11" version="1">MSEKKMVTLDGNEAAAHVAHAVNEVISIYPITPSSPMGEWSDQWSAESRPNIWGTVPLVEEMQSEAGASGAYHGALQAGALGTTFTASQGLLLMIPNMYKIAGELTSTVMHVTARSVAAHALSIFGDHSDVMAVRNTGWAMLSSATVQESMDNALIAQMATLEGKVPVLHFFDGFRTSHEEMKIEEIPYDAMRACIDDDLVREHRYNRLTPDAPFIRGTAQNPDVFFQSMEGRNRYYADMPDTVQQAMDKFAKTIGRQYHLFDYYGSPEAERVIIIMGSGAAVAREAVDRLNQEGEKVGLIIVRLFRPFDITRFTNALPGTVKKIAVLDRSKDPAANSEPLCADVKEALNGSGITIVGGRYGLSSKDFTPAMVKGVYDELRKLAPKDGFTIGIEDDVTYTSLPYDPSFDTENPKTVRCLFYGLGSDGTVGANKNSIKIIGQETDLYAQGYYSYDSKKSGGITVSHLRFGPDPIYASYLINKANFLACHVYSFLEKLDILKNAADGGTFLLNAPFGPEQIWDKLPKTYQQKIIDKHLKLYVIDAVKIAKQTGMGSRTNTIMQTCFFAISGILPQDKAIKAIKDSIIKSYTKKGQAIVDKNIKAVDETLANLYQVKVPAEATSAFDILPPVAEDAPEFVKQILGPMMIMEGDSLPVSALPEDGTYPSATTQYEKRNIAIDIPVWDPSLCIQCGKCVLVCPHAAIRAKVYAPEKLEQAPAAFRHAQAKFPNFKDYDFTIQTAPEDCTGCGLCAANCPINKTKAEDPHRPLIMRTQMPIRETEKANWNYFLSLPETDKAKLNTATVKDVQLLRPLFEFSGACAGCGETPYLKLLSQLFGDRAIIANATGCSSIYGGNLPTTPWAVNDQGRGPAWSNSLFEDAAEFGLGFRLTIDKHREYAAELLTKMTPELGEQTVREILDAPQTTGEQIKAVTDEIDRLKEQLCCIETQQAEELESVIDNLAKKSVWCVGGDGWAYDIGYGGLDHVIASGKNVNILVLDTEVYSNTGGQASKSTPRGAVAKFAAAGKRMGKKDLAMMAMSYGSVYVGKVALGANDAHTVKVFQEAEAYEGPSIIIAYCHCIAHGIDMVKGLDQQKKAVDSGHWMLMRYNPDLAKEGKNPLVIDSKEPSLPLEDYIYNEVRYKSLKATAPEEAAQLLEEEKKAIADRWRFYRHMAEMKMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7G2</accession>
    <name>A0A011A7G2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit,precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit</fullName>
            <ecNumber evidence="8">2.1.1.132</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.132" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484763.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.104"/>
    <dbReference type="HOGENOM" id="CLU_031955_1_2_0"/>
    <dbReference type="OrthoDB" id="1706318at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046025">
        <property type="term" value="F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11644">
        <property type="entry name" value="Precorrin-6Y-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012818">
        <property type="entry name" value="CbiE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014008">
        <property type="entry name" value="Cbl_synth_MTase_CbiT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02467">
        <property type="entry name" value="CbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02469">
        <property type="entry name" value="CbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="243"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG77991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="405" mass="42857" checksum="23303E2DDC7D31F6" modified="2014-06-11" version="1">MGNKLYVLGAGPGGREEVTPAVSAAIAASRAVACAARHLHIAAGHPNVIEMKNFQDTFRRLREELEQGDAAVVVSGDPGIFSLLPLIKKNFPSHGIVVLPGVSSLQSLCAKAGETWQEAVVLSGHGREIGTPRILDAVEHARAVIFFCDAQKGPAWLCARLCEAGLGEVEAVVGERLGAADERVSRGAAREFVNESFDALSIVLLINENFTERPPLLPEDADFIRGGAPMTREEVRAVITAKLRLTPDSVVWDLGAGTGSVSVAAARLCRELHAAEIDAEAAALVRANAEKFRLHNVTVHEGSALAVMEHLPDPDVVFIGGSGPELPAILERTAARGAGIRVVVSAVSLKTIVLCTEVLAGDKFENFDAAQVAVSRMKTVGKTQIWQAQNPVVIFSATTRAAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7H8</accession>
    <name>A0A011A7H8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709874.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.119"/>
    <dbReference type="HOGENOM" id="CLU_045089_0_0_0"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="193"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="355" mass="39834" checksum="CB27BF0EFABADA01" modified="2014-06-11" version="1">MKISSLELNNFMLFDKLSLRWSPKINIISGENSTGKTTLIKAMYAVLKGVSENRLDKMNKEEIEGSLVKKIQGVFRPDDDKIGRLVSRGSGGGRASLSLGIGGEDSVSVGFSGRQDRHADVSVNIGVAEDGTAPYFPVYIPPKEMISATEHFQSLYEAYHIDFEEMYYDLTKLLDRPLKKGGNTEQQNSVVESFGRIINGSVVQRDKKFYLKMKGKGEFEMGLVSEGYRKLATIIYLIYSGSLNENSILFWDEPETNMNPMMIKPIAEAVAKLAEMGVQVFITTHDYFVQQSFNLLSAYPAAGAAPPEIKFISLYKEDDRLLFEEGATVSELNHNSIMEEFDNLYDREQDLIYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A847</accession>
    <name>A0A011A847_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding domain-containing protein, AraC-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484806.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052345_4_3_0"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="223"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="319" mass="36247" checksum="8C456AD81A801436" modified="2014-06-11" version="1">MIIQFSQQDFAPRSFVASNSPENTAEQNCDGGRLEIPENIAGGRVAADAVSPGLSLICSEMSFAKDTFFREEYQDRDVLQIAFCLQGNCEWSYGNGARPHQLAPAECSLQCGVMRKCDSFFPRGPYRALSLSLGRERFADVIECLKDVRLLDSGDMIRTRVFAGTPHLRLLIRQLTECPPDYKLRKLFLEGKALELLSVFCSEVIGRKEKKGDVSREDRRCLRQARERIDEQFLLPLTISQIAKECHMSETKLKRGFKNCFGCTVYEYMVEKRMELAHSLLSSGKYKVKDVVWMAGYSNAGHFIKMFRKRYGLTPGEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8E2</accession>
    <name>A0A011A8E2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441561.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_4_0_0"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="766"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="829" mass="92215" checksum="76A0D160ECD59521" modified="2014-06-11" version="1">MRRGVGFKNNDGTYIPPQLIEKLGTMLTSPLTLIEAGSGFGKTTAVAEVLEDVQEQKANVYWHTFLGEPPEKAWQALCGLIAHADGKAAVWLGNLGRPSLSSLPDLASILRDIRCSKTTVIVLDNWQLAGFEISAQLIEALSLHRGKKLHIVVITQPAAAAARTTSNPRMALIGNDSFRYTRENIAEFFLHSRITLDEEQLDMLCDITEGWIAALRLQLSAYAENGRFETAGGISQLIETAVWNKLTEQEREENLRLSIPKNFTIEQAAAILRRPELSEDEIARLDNDPFVRRDANEGTYTFHSLKRAYLADKLSRRSREYQLDALRRAAEGYAARGDVGAAASCYARTRDYEAIFALPFGDAALSQSIRYARGESIDAIFDDCPKEILLRHPEIMLRAALEFFLKGDFEHFSRAFALAEESCELEERRGGERAINLRGELEFLKFFPAFNDVKAMCAAHEKAWKILRGPLKTLYFNDDTWTFGISSVVCMFWRESGSLREELKEVENGMPCYYKLRNGHGMGAPAAMAAETALMSGDDESAQNLAIKAIYSAEIKHQDSICFCGELVLARIAALRGESGKFSKTLAEMRARAFEGRDPYGVVTAELCRAHLGTMAGIGGLIPEWTLDARRIREKVFAAAVPFALIPLAKYLLDNDPVSFGALVGEFIDESRRFHMLLPEIYFRLYAVRHKQRSGESGEAETELNAALDLALPDKIYLPFAEQGSEIAPLLVALRPQIGDKQAVDAILALSQRLQYNISGIPDAGTQPGDKPLSAREREVARLLAEGLTTQEAAERLSITNNTVCTMKKSVYKKLKVRSRVELAKRCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8E9</accession>
    <name>A0A011A8E9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484819.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_2_0"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041612">
        <property type="entry name" value="YfiR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17922">
        <property type="entry name" value="TetR_C_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="211" mass="24248" checksum="13AEB0C6B4DC8CFE" modified="2014-06-11" version="1">MPKVNDVRREIMDKAIRERVFSESCRILKDDGWGGFTMEKLAAAVGVAKGTLYNYFKDKLDVIVFVNEQLFDEVAHDVEALFTAEGDCRDILRASMSRGLEKMTDFRFLRMVMIEMHMKSASKEEKKMFVRDPADRVRSAMVRFFKRGVDEGAFKPLPPETLEIFFTAAFDGLEVRSNFDQNFTPAVGGMFDDLMDMIIDGVSIHEKRDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8H2</accession>
    <name>A0A011A8H2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator with HTH domain and aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441623.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.456"/>
    <dbReference type="HOGENOM" id="CLU_017584_0_6_0"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="50"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="387" mass="43807" checksum="E5C4B90752D8AFE0" modified="2014-06-11" version="1">MRYSDRILSTPSSFIRDILKVTQDPSVTSFAGGLPNPISFPQEALKESACRIIDNEGGKVFQYSTTEGHLPLRRFVADKYNRNFGLNITPEDILITTGSQQALDLIAKVLLNKGDRVIIEEPGYLGAIQAFCMFEPEFMPVTLEDDGLNLEKLEEALKQERVKFAYVVPNFQNPTGLTYTKERREAVCALFDKYDTVLVEDDPYGELRFKGEKLPYIGAGKLAHSVLLGTFSKTVTPGMRLGFVITQDRELMHHLVTAKQSSDLHTNIFSQYMIADYLAHNEYQQHVDKITALYRTQAEAMLSAMREYFPAHVKYTEPEGGMFIWVTLPEGQSALDLFRKAMEKKVAFVPGDPFYAGKTNVNTFRLNYTNSTPEIIREGIRRLAEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8J3</accession>
    <name>A0A011A8J3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0438</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the auxin efflux carrier (TC 2.A.69) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709155.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056175_3_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="313" mass="33748" checksum="670808AE2A3DA3AC" modified="2014-06-11" version="1">MFGFFLVLPLVIIIITGNQLRARGFYSANDISALMKTLYWVILPPLLFRTTYIAGTEVLRQPNLLIASTLCYIITIIAAYAGSRAFAHKGDVRRTAVSVFSSFRSNNIYLGFPVIQLAMGEAGLHEASIYVAVTTVSFQLLSIAAGEAVLYGRPSARGILDMLRKLVLNPLIISCVLGVIAAASGFPIHFVFDEAMKLMSGAATAVALLALGGSLDLSRMGKIVKILSRTWFDTLIKLAVNPAIMYAVLLLFPIPKDLFNVTVMLSAMPNAVNCFILARGMGMDSEYAADLVAATTLLGIISIPAWAYILGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8K6</accession>
    <name>A0A011A8K6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDDEXK_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441685.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1183356_0_0_0"/>
    <dbReference type="OrthoDB" id="1206319at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="86"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="234" mass="26001" checksum="C15D35A8E31E5676" modified="2014-06-11" version="1">MSSKGLEKGPAKAAKAHIRYKTADGKVVPGVTTVLGVINKPALVKWANNLGLQGIDSSAYVDETARIGTLAHEMIQEYLGGPVVDRGAYTKDQIDAAENALISFFEWERHQEGAKMVTRAIELPLVSEAYRFGGTIDWYGEIGGRMWLVDIKSSKGLFTEHELQVAAYYKMLQENGYAVDGVRLLRVGRTEDEGFDDHVLSPVKLDAGWEVFENALRLYRTKQQYEAQARKGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8N6</accession>
    <name>A0A011A8N6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441743.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1841627_0_0_0"/>
    <dbReference type="OrthoDB" id="2223117at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="139" mass="14971" checksum="097E696B7826648A" modified="2014-06-11" version="1">MGNINWTKLDTPEMKFARAKEAKRRQIWAAGDAVLAEVKANYTEAEIESWRKQEQGAKDFAAGNTETEAAQFVAAIATTRGIETAVLVEKILANVAAYGALSASVIGKQQRLDTAVTAATTQAELDAITWEAANNDNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A928</accession>
    <name>A0A011A928_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3023980_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="55" mass="6273" checksum="1F2A84D4DA854EC0" modified="2014-06-11" version="1">MTENKKPYFMVRVDEHKASAFKSALKSHGQSAQFILEKAIDKYIEESKTVESPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A959</accession>
    <name>A0A011A959_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484860.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_2_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="22"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="758" mass="82562" checksum="58D1F04B9D70628B" modified="2014-06-11" version="1">MKENYSYAGRSYPINDAVYKTTGEMIYASDIRLPGMLYLELACSTHPHARIRAVDSRAARRLRGVVEVFSYENSPHKRYNNCRKTPLQQGVPEDKLLYTDRARYVGDVVAGVLAESREAAEEGARRLVIDYEDLPAAVSMSESTAPDACPVHDGGNILCNVDFSCGGGTEAGLTESGRCRSSLSSQQMNHITMETHAYLADYRNGELTIWTPTQGIYGVRTVVCDLFGLPYNMVRVVKVPMGGSFGGKQEFIYEPHAAYAALQSGRPVRLHLSRRQAIVSTTCRPSLETAIEMGFTKEGRITECHVLNDANAGAYAGNAVNLEDTMKAKMTRSYKFPSFHFKGRAIYTNTPIGGGMRGWGAPEMVTPLEIFLNAAARRLGLDPVELRLRNTYDPGDSEIAHGLSLGNCRGKDCLTIGAKEFSWDERRKRPREKGRLRRGIGVAYGGYQNGFYPRPSNLSVMTIKMNEDGSVCLQTSVHEVGCGTVRSLQIIAAEILSVAPDKIYVTEGDTKYTQFDLGSYGSRTTFIAGECARRAALALKDSLLKAAASLLGLPETELELRDEYVISASHPEVKMSYAEAASRALMEKGVALYDAVEWKGVSNPGSFVANFAEAEVDTLTGMVRVTDFLSVNDVGFALNRQMVENQVRGGIQMAAGYALCEDVAVDAAGNPKNDRLSRYHTLNSADMPRVRVVLVEEGGDEGPFGAKTIGEVCTIAGTAAIASAVSDALGKEITALPLTPERIVKWITTEGVPDDDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9E0</accession>
    <name>A0A011A9E0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbon dioxide concentrating mechanism/carboxysome shell protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442023.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.821"/>
    <dbReference type="HOGENOM" id="CLU_064903_0_2_0"/>
    <dbReference type="OrthoDB" id="1802372at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="3">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="188" mass="19972" checksum="44F12C1190554E62" modified="2014-06-11" version="1">MKALGLMEFLGYLPAVDGLDVALKAAGVRLQSCRRDGGGLVSLLITGEVAAVKASLSAVRAASGKALLSSSVIARPADQLAAMLEGMSPSPLRAPGAEKREAGADKSEKKSLLPAALPPEREEEAAPSKEPEKELKREESFVDKELGAMTLRELRALARRLGLSMGEEKIRTSNRKTLIAAIEREQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9V3</accession>
    <name>A0A011A9V3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442164.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962086_0_0_0"/>
    <dbReference type="OrthoDB" id="1017413at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="289" mass="31929" checksum="1294CA80B143E586" modified="2014-06-11" version="1">MRNFSYVKIKDTDELLQRLNERNGRIWAGGTDFMLKLKHNMTRPGIVFDISCVKELCNISSDGDYMRIGSCVKLAEIVNSKLIKDWAPLLVMFAGNIGSMEVRNVGTIGGNICASRANCGVCFLPGCRAMTGDRSTRPCRNAAYADMLLPLKAYGASVVIKSNAGERHVLIKDFFKGDGGIDLNVNEVLTEVLLQGMCKGHFGMAELRQPLKMGFPYISVIARRRSDSYDLTIGGSTKKIYSFQNVCRNNINSLCGEIEFVGTLKLSEGYRKKALPSVMQEAIDRAGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9Z8</accession>
    <name>A0A011A9Z8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fusA</name>
        <name evidence="8" type="ORF">Cloev_0976</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1046"/>
    <dbReference type="HOGENOM" id="CLU_002794_4_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="7"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="80"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="688" mass="75681" checksum="BC3484655501CE50" modified="2014-06-11" version="1">MQGIDLSTVRNIGIAAHIDAGKTTTTERILFYTGRKHKLGETHEGAATMDWMEQERERGITITSAATTCFWGDCLINIIDTPGHVDFTVEVERSMRVLDGAVSVFCAVGGVEPQSETVWRQADKYGVPRIAFVNKMDRVGADFFAVVDQMRKRLGAKAIPIQIPIGVEDGFTGMVDLVHEKAVIYDDTLGTEFHSADIPPQLEEEAALARMEMLEMLADYDDEMMELYLEGTDIPLDMVKRVIRKATISLDIVPVMCGSAFKNKGVQPLLDAVVAYLPSPLDMPHLVGVDPDDTAKEIEVKASADAPFAALAFKIMVDPFVGRLAFCRVYSGSIESGTSIYNTNTRRRERVGRILRMHANKREEMDGAQAGLIVAIPGLKQVRTGDTLCDEKHPVLLENLIFPEPVISLSVEPMSKADQIKLAKGLEALSEEDPTFRVSVNEDTGQTLISGMGELHLEIIVDRLRREFNVEVKVGRPQVAYREAIRKPARAQGKFVRQSGGKGQYGDVVLEVEPLEEGKGFEWVDKIVGGVVPKEYVPAAQKGVEEALNNGVLGGYPVIGIKVAIVDGSYHEVDSSEMAFRIAGSMAIKEALKKADPVLMEPVMNVEVVVPEEYMGDVIGDLSSRRGRVAEMGVRANARIVKAFVPLAEMFGYATDLRSKTSGRASYTMSFDHYEEVPRNVAEELLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA35</accession>
    <name>A0A011AA35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442319.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_456095_0_0_0"/>
    <dbReference type="OrthoDB" id="581937at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458620" evidence="2">
        <location>
            <begin position="25"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="592" mass="62974" checksum="C2E0407E809B0682" modified="2014-06-11" version="1">MRKFLVLLTAFAAAVFSLCPASYADVTLKAESLVFDGANDDLMGAGTATPDGTPDAVFTLTMTGAQAIREISLKNETTGVTWSTSNMKNLLLVKNSKGELLNKTGRMTITPVILAAQFTLMINDAAGAIPKDSTFIANVTLIDKAETSASTTVKAVAAKAGDKKGEDKKTDDAKKGPAKDEIVLFESRGVSEQDFAGEKKSVGTNGRNDYRFDAHFKLSTGIQVKGVKITAENGSQKAEWDTVPGSKAPLAVVIDESNNILNKTDGSLSFGGDVRCMLFLDDKQGILEKPKTSAKILVTLSDGRMLELKATEGKKAVAKDTVSVEYNGASKYDFVGQSKKFESNMTPDSFVKIAINAKGRITGVRVTNLKNGQLWDTIQGNDKSYLAAVLTPDGKRLNKANGSVAIDVDGTEELHIAFDEEKDQNTGPYRVTIVFEDGRLMEGATKAAAGKDKNESAVTKADRSVTFVSKKPESVAVDLVGKNKKKGANGAKDMALTVKAAGKGVIKAMVLADSGGAGWDTLAANNGRWLLGVREGGKFLNAANGTVKLNVNGTKTYQLLMQNNGKLNAKNGKLLLTVTWGDGEVTETELKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA67</accession>
    <name>A0A011AA67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ORF">Cloev_1065</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1133"/>
    <dbReference type="HOGENOM" id="CLU_043846_2_0_0"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="16"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="166"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="318" mass="35503" checksum="5A2ACCED97FB3A8C" modified="2014-06-11" version="1">MSAMLNEIGQMTWRHRSVIDLDCWTREELYFFLDQSRHMENVMDRPVKKVPALRGKMCVNLFFENSTRTRVSFELAEKMLSADVVNWSVSGSSAAKGETMRDTAWTLEAMGADIVVMRHGAVGAAQYLASKLKRGIVLNAGDGTHAHPTQALLDVYTAWKHFGDLEGRKIALVGDVLHSRVARSDVIAFKTMGCDVVLSGPPTLMPREIEQLGVKYDRDPRKAVEKADMVYLLRIQRERQQDGLFPSVDEYHRWWGADEELMKYANPGALAMHPGPINRGVEIASEVADGHQSVILEQVRSGVATRMALLYLCGGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAD0</accession>
    <name>A0A011AAD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442451.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1209"/>
    <dbReference type="HOGENOM" id="CLU_1123368_0_0_0"/>
    <dbReference type="OrthoDB" id="1534863at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459493" evidence="2">
        <location>
            <begin position="26"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="254" mass="29341" checksum="0A964B11E5F87018" modified="2014-06-11" version="1">MRKKIIPILLITALLSLLAIPFASADSFGQILDRWTKSRKYTGEDKLSNLEIKATYYSAEFIEAYIQKEAEANLWTKQEAEDYKYKFLSALKLDEMIPIQIEFNNNAETMHMGPFDIMVKLQIKNKSYKPVDYDKRLNFKFQGRKEGLVYFPRYDEKTGRDLLEGVKNVTLELRSAVAPTITKGQPTRFIWDVSDDAPQKLYQGTTAARIETDRLIKRLEKLRKDKAEEEAKLASINGEISTIQSRLDELAKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCF8</accession>
    <name>A0A010YCF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative manganese efflux pump MntP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mntP</name>
        <name evidence="9" type="ORF">Cloev_0009</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probably functions as a manganese efflux pump.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MntP (TC 9.B.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096410_3_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01521">
        <property type="entry name" value="MntP_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003810">
        <property type="entry name" value="Mntp/YtaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022929">
        <property type="entry name" value="Put_MntP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35529">
        <property type="entry name" value="PTHR35529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02659">
        <property type="entry name" value="Mntp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="187" mass="19578" checksum="D4185E70DE284D1B" modified="2014-06-11" version="1">MMFGEYLTLGATAASLAMDAFSVSICIGLCHERLRLREALILGAAFGFFQFFMPLLGGEIAEHLSGFFDIWTPWIAAALIIWVAVNMIKEARDCENGGKSCMSVTFKSVAVLALATSLDALAVGFSIESTGGSALTLAVLAGIITLSLSIFGALVGKRLGSTFGKKAEYLGGGVLLAIAAKIIFDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCH9</accession>
    <name>A0A010YCH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type cobalt transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441225.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="269" mass="29343" checksum="8203E7B044113B28" modified="2014-06-11" version="1">MIEFRNVSYSYGDGPLLSNISFHLADGSFTAVAGENGAGKSTLCRLAAALLRPTGGEIVSNGLCTSKEKGAAFAAFTGFLFQNPDRQICRATVYEEIMFGLRCISSNVKEAEHAAAEMIEEFGFSPDQEIFYMSRGERQMLALASVLARRPRILIADEPTSGLDCRQYGFVARKLREARERGATVLMVTHDMELAEETADEMLVVGGGAVRAHGPAAELLSDGELMERSSLRRTEMRELADILGGDFAKAGSVDEMAEIIKERKKRMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCJ7</accession>
    <name>A0A010YCJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441238.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.74"/>
    <dbReference type="HOGENOM" id="CLU_021594_4_0_0"/>
    <dbReference type="OrthoDB" id="734949at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="430" mass="46475" checksum="F40F2A590E4BA375" modified="2014-06-11" version="1">MANEKNAERKVLYGQQTKLNLENMSFSGERLSRFPEYISAAAKVKKACAMANDGAGFLPPEVAKNICSACDLLIGGEYNDQFPVDVFHGGGGIGINMNLNEVIASLAGGGTAPIDQVNLNQSTSDVCHSALHITIVNEIDRLIPILDDFAKTLRRKADDFTNITTIARTCWQDGLTASVGVLFSSCASALERNIGKIRALRNEFLKVNLGWTVIGTGSGADERYRKLVLGVLCRVTGLPLSWPEDKCDAAQYPDDIASLSSEIATTAAVLMKLSADLRLLSSGPETGLHELNLPAVQAGSSFFPGKVNPVVPEMMIQCGMLIEGNNAVVGRTVSMGEIHINLWEIMAGFLTLKNISMLGKAARLLNDRCLSGVTVNADVCERYAHSSIPTITAFKEKFGYQRISALVKEFGTQSAIEKLEQIEREEKGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCZ5</accession>
    <name>A0A010YCZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA/RNA helicase, superfamily II, SNF2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441380.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.224"/>
    <dbReference type="HOGENOM" id="CLU_000315_21_8_0"/>
    <dbReference type="OrthoDB" id="325071at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022138">
        <property type="entry name" value="Helicase_SWF/SNF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12419">
        <property type="entry name" value="DUF3670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="563"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="847"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1025" mass="115867" checksum="860F08BD05DDEBE3" modified="2014-06-11" version="1">MLILHTAFEQDQIYLWGESSFENKKLRNRERAGGNMLPWSAKPQQLRAALRECGVRHGRRTPADESFTASLLIPARGKTPLPSSPILGEVPDSGEPPALSAFYVDAVALSFTEFTQLLRIIRESGERLSFPGLLFADDFKFMCRALEYSAALVQRGAYIPDMEPRGDSFVSQWRPMILAKYQDEFSAYAAAMPPVLCAFSTDGPPAAPCPKRTGAMRLLECMTDMLIRSSQLGGTDRGRRVNAGNPHEIWLRSLIWQKAPLVKWNEEMASLYPQIRAWADSLKAVTAQPWRLFMRLEEPIGEGERDWILSWHLQSTQDPSLIIPAERVWSPTETERGWFDHTQTNPRRYMLQILGHLATRVPYIAKSLEVSYPCECVLSLDNLFDFLQNHLTSIMDQGIQVQFPSTWGQISDRPRLSVRAALHDGNAFAPGGQLHLSDMLDVDWSVALGDDLLTADELAMLTELKTPLTNIRGRWVILYRDEVEKITTALKKLPGKIERKEALLSSLRQEHMEAPLSDVTGSPWLANVRSLLLGAEPLEEMAAPEGFAGRLRPYQAKGLAWLARLVRLGMGACLADDMGLGKTVQTLALIKNLRILGERRPILLICPTSVMENWRRETERFVPGTKTLIHHGMKRNKKNLFTDEALAETLVISSYSLLYRDNSLFAKIEWAGIILDEAQNIKNPDTCQSRAARAVRADWHIALTGTPVENHVGDMWSIMEFLMPGLMPNRARFSREILRPVQAGEKKAMDKVRRMTAPFILRRLKTDKEIISDLPEKIESKEFCPLSREQATLYSAVTSSLERELEGTEGIKRKGMVLGAITALKQICDHPLLYLKDKSEIDNRSGKLARLAEIAEEMLASGDRALIFTQYAEMGELLKKYLQETFGREALFLHGGVPREKRDEMVRRFQEEEDGPPFFVLSLKAGGTGLNLTRANHVVMFDRWWNPAVEQQAVDRAYRIGQQNNVQVHYFCCRGTLEEKIESLIEAKRDLAEMLVGTGESWLSELSDSDLHELFSLEKEAVDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDF1</accession>
    <name>A0A010YDF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-glutamate cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441520.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.365"/>
    <dbReference type="HOGENOM" id="CLU_059759_0_0_0"/>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009906">
        <property type="entry name" value="D-Glu_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038021">
        <property type="entry name" value="Putative_hydro-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016938">
        <property type="entry name" value="UPF0317"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07286">
        <property type="entry name" value="DUF1445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029755">
        <property type="entry name" value="UCP029755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160920">
        <property type="entry name" value="SSF160920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="258" mass="28641" checksum="5A2AB66884EB1FD0" modified="2014-06-11" version="1">MSDFYFKSPGEARLFFRKSETAIPTAGLCPEYIQANLVILSDEDSPEFLEFAHMNPKPCPLLEVLCDGTPISKEMAPQSDVTTDIPKYSVYKNGVLVEEPLSVQQYWDKNMTGFLIGCSLTFEAALVNAGIRLKHYEENKRVPMYDTNIACAPTKKFFGNYVVSMRPIKKDLIDTAVEITSKMEYAHGAPVHIGDPSKIGITNVNCPDYGDALSINDDEVPVFWACGVTPQAVAKKAKPKMMIAHSPGYMLICDKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDL0</accession>
    <name>A0A010YDL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C4-dicarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709047.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.401"/>
    <dbReference type="HOGENOM" id="CLU_046665_1_0_0"/>
    <dbReference type="OrthoDB" id="646039at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="458" mass="48188" checksum="926C69C72B146B18" modified="2014-06-11" version="1">MVTELSVIHFIYVAVVFVCIALMLCRKDIVIVCVLGTLLIGAIHTGSAIEAIQVLFRALMVAGEDLFAIMLVISLMVAMLRVLNRMGADYLMFLPFKKVITGANQSYLFLGIVSYIAASLFWPTPATALVGTLLIPICIKAGLTPMAAAVAVNIFGHGMGLSGDLVIQGALKLSSTAANITVDDMYFKVALLSITTGVVAGFAGWLMLREELKTFKGSDEWKKYKETSEQEGSYKPCAVYFAVGVPVTFCCIIAAMIHYDIKGGDATALIGGTALIILTAGTVVNDAKKSFDDIVAFLKEGFLFGIKIFAPVIPIAAFFFLGANSVTEILGEGAPKCLFDVGNWLAYHLPMGRVPVAFGNLIVGMIAGIEGSGFTGLPLTGSLAQAIGGPLGLDVAYIASVGQMGSIWTGGGCLVPWAFGLAATAGIAGVNPIELARRNFIPVLCGLLVSTVLAIFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDR3</accession>
    <name>A0A010YDR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase (Metallo-beta-lactamase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484826.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010363_0_3_0"/>
    <dbReference type="OrthoDB" id="1796527at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
        <property type="entry name" value="ComA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457571" evidence="1">
        <location>
            <begin position="32"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="44"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="286" mass="31562" checksum="07C799BB3202CCBF" modified="2014-06-11" version="1">MKNKTKILPQVLLTMLLLAYALFSVVPAAGAAPPLRYYAVDVGQGDCSLFILPNGQTIVIDAGPEKNAKKTVRYLKSCGVKKVDLLVATHPHEDHIGGMRELLSAFPVEKIWDSGYNHGSRIQRDFYRAIKEGKIAFGRPKRGFSDKFGDVEVKVLAPVKQLKNTNSDANNNGLVLLVTYGDISFLMTGDMEREERATIAPLPRAVVLKAAHHGSRNGTDKRTLREVSPEIIVLSYAKGNSYGHPHKEVVRAIREAGVRRFDTADGAVKLRTDGKSITFERKRAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDT4</accession>
    <name>A0A010YDT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.512"/>
    <dbReference type="HOGENOM" id="CLU_1591663_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="19459" checksum="74C1ACB55B8823B4" modified="2014-06-11" version="1">MCKYVKRPVVVEAVKFEDSTECFDKLQALGLDPVRVNYADKDNPVIKIDTLEGEMTGQVGDYVIRGVNGEFYPCKPDIFEKTYAKEGSYPTKHLSFGAAFDYLKIGNVDYMRLPQWKEDVKIRIQRPDENSKMRAPYLYVESRFGRVPWKETMIELFSDEWEVGFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDX5</accession>
    <name>A0A010YDX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441764.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.561"/>
    <dbReference type="HOGENOM" id="CLU_084424_0_0_0"/>
    <dbReference type="OrthoDB" id="1944295at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="287" mass="33006" checksum="B259470C34328CC7" modified="2014-06-11" version="1">MRDSEGRQRHFVIRDKKDESYDSPSVRRRGVIKEREEEMEEALEEPRAPRQRKSLREREMEEEDEQNILRRGRGNKRIKEEEDYEEEEEENYGSKAPKVVRVFAWIALMIILFACGYLATNYFFSWSDKKGGERIGSVYGTGSEVKESAATEETAASNTKYTLYLPDGEGFQSRGIDITGGGTREEDIAKVMSMYVDSLKETKALDPAVSINEIFQSGDWLYLNMTPTFQSSLKSLGKAKAEKLLSGFTKTVQENFPPLKKVKFYVNSKEITDKNPVDLTQPWERTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE55</accession>
    <name>A0A010YE55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710355.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110735_6_0_0"/>
    <dbReference type="OrthoDB" id="1583204at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009936">
        <property type="entry name" value="DUF1468"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07331">
        <property type="entry name" value="TctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="146" mass="15453" checksum="5FB85D6A0EEC1690" modified="2014-06-11" version="1">MNGDIIVGIFSAVFSAAYVVAAWLLPDAAIGNPMAPKYFPLMVGLLALAFSLALIVRGAKKGCAAKKGRAPDPGHWVLIGGLIACCLAYAAILDNLGFLISTPLFLGAMLFLVNGVKGWKANVATALCFSFGVWYIFEKIFQITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEB7</accession>
    <name>A0A010YEB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710485.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.732"/>
    <dbReference type="HOGENOM" id="CLU_052511_3_1_0"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="155" mass="16702" checksum="C1135401D2F8D941" modified="2014-06-11" version="1">MMISFELNHKKYRMNVDPTKRLVDFLRDEMGLTGTKEGCGEGECGACTVILDKKAVHACLVLTGQINKKSLLTVEGLAQNGEPSPLQKAFIKHGAVQCGYCTPGMLMSASALLMENPRPTEAEVRLALAGNICRCGDYSAIVDAVLDAAEAEARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEF6</accession>
    <name>A0A010YEF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR02757 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.772"/>
    <dbReference type="HOGENOM" id="CLU_064298_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014127">
        <property type="entry name" value="CHP02757"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09674">
        <property type="entry name" value="DUF2400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02757">
        <property type="entry name" value="TIGR02757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="280" mass="31630" checksum="28005A8A242CFA28" modified="2014-06-11" version="1">MASTPSNSALKPLEETPARIASREIFEKIYDDYNKRIYVSPDPLQFLYDYEDTADREVVGLIASGLAYGKVAQILKSVRKVLDALGPHPAEYLKNSCRRDHEEKLCGFVHRFTDCGEMCGFLAATGEVLRRCGSLEELFVTGYKGDMGAAMENFADTFNRCAGRENMFLLPRPSKGSACKRMALFLRWMVRRDDVDPGGWRGISPAELLIPLDTHMFNITTTLGLCRSRSANGRAAAEITENFREICPGDPVKYDFALTRYGIREEMTVEELFAKWHLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEI4</accession>
    <name>A0A010YEI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445258.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.799"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_0"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="59"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="371" mass="40854" checksum="8697A07C3F8DF2AC" modified="2014-06-11" version="1">MKEIILKTELHRFKTCKEFAEDFALGRGDFIFTIRPIYEKYFAPLGLPLKSLFMEDFGAGEPTDVMTDEIIEAVTALGFERLIAVGGGSIVDIAKIVAASGGKKTDELYAAPSEIRRGRGFVIVPTTCGTGSEVTNISIVNRTRVGTKMGLVADALFADQAVLIPELLHDLPFDVFAASSIDALVHAVESALSPKATAFSKLLSCKAVEIIIKNYLKIAEEGRKARIPLLDSFLTAANYAGIAFGTAGCAAVHALSYPLGGKYHVPHGESNYAVFTGVMKNYIEIKEDGEIAEMMGFISSLLCCRKDDAWEALEDLLNKILPKKSLHEYGVEEEELEEFTDSVMQRQQRLMSNNFVPLDRDRVLKIYMELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEI9</accession>
    <name>A0A010YEI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442001.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1874404_0_0_0"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="137" mass="15448" checksum="1CD68BB6D66A03A4" modified="2014-06-11" version="1">MIGKEIIVRRKRMSLTQRELARLINVKSTTMHQYEVGLRKIPLEALGNIAKILQCSPEDLAFEEFGLPAPSETTAGDSEIKGSANDDGGKLIFADPLDNEIVALLKDLDQIAKEKVITYMRDQKVITGYYRAVRERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YER3</accession>
    <name>A0A010YER3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdenum-pterin binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710771.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.881"/>
    <dbReference type="HOGENOM" id="CLU_118993_0_1_0"/>
    <dbReference type="OrthoDB" id="1782925at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00638">
        <property type="entry name" value="Mop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mop" evidence="3">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Mop" evidence="3">
        <location>
            <begin position="74"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="142" mass="14609" checksum="BAD6FF1AFFD9F883" modified="2014-06-11" version="1">MFLSARNQLKATVASVKQGAVNNEVSLRLEKGTMLTSIITSTSCENLGLKEGGEAYAVIKASNVMIGECGGGLRLSARNQLKGVVKAVIEGAVNCEVEVTLEGGEEVTSIITMASAKKLALAPGKAVSAIVKASDVMVGVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF33</accession>
    <name>A0A010YF33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902261_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="308" mass="36784" checksum="BD01F868150CD4D1" modified="2014-06-11" version="1">MRRVKRIIDDMRRRCGYKRMLSQHPHEVDILFDVISKRLGREALIRQVKNKKDYYLIDIAFSYFQKADRNRQVGYRSGFCFRKPSFIYKELMFIIVHSPIMFSFFQQNFDYDVFRSILEKTGKYRDCNYMYYTIFNKNRDTKETFEISTESMDEFLKEIDLVESQYGFAKTVFSAKNSSKANLGNTYYLLIANKFTTENISEIIDISWDLFMWLYPSKPLFSRDATLNRSMRNIERKCEFHHIKNLPNFMTDIECEGVIQAAHIKPHHKGGSDKMENGLWLCEKHHRLTEGKISGRRNKTAIDVRYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF80</accession>
    <name>A0A010YF80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type cobalt transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442298.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1713578at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="276" mass="29821" checksum="9F76B3BDB3114F35" modified="2014-06-11" version="1">MIQERQFILKGAEFCYPNASEKILKGIDLEIRAGERVALLGSNGSGKSTLLKLLSALLIPTQGLCFVGGTDTSEAKGYELRGISAIVFQNPEDQIVASTVEEEVAFGPENLGCPPEEILARLEEALAATGLGDRREQLVASLSGGQKQRLALAGALAMHPKAILLDEAMSMLDPRSRRDFTEIIAAEHKKGLTIVEVTHRLDEIRGADRVIVLADGVISTDVSAKEFFKKSEAELLAMNLAKPPLDRLHERLVLDGLIPAETAASVEGIEEKLLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF86</accession>
    <name>A0A010YF86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711046.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1089"/>
    <dbReference type="HOGENOM" id="CLU_091233_3_0_0"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="159" mass="17183" checksum="5FC9375C5FCC37DB" modified="2014-06-11" version="1">MLSSKLLDDIGRQILRILQEDGRISFNELGRRVGLSSPAVAERVRRMEEAGIILGYRAVVDQSRVGYPIMAFIRLSIPVSFLAQADELAKAIPEVLECHHLTGSDGVILKVVVSSVGHLEEVISQMGSCGMTTTAIVLSSPVVSRPIDPIKQQTPPPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFG1</accession>
    <name>A0A010YFG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442433.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095708_0_0_0"/>
    <dbReference type="OrthoDB" id="1813646at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045717">
        <property type="term" value="P:negative regulation of fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017275">
        <property type="entry name" value="Transcription_factor_FapR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037733">
        <property type="entry name" value="Transcription_factor_FapR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="196" mass="21718" checksum="95D7473ADC77D6AE" modified="2014-06-11" version="1">MRSEGRKQRHKQLVNLIESNPLLTDEEISSALGVSLSTVRLDRGLLAIPELRERMRSMAEHATSRLKSLCADEVVGELVGLEPSKWALSMLSTNPDMAFRQTEMVGDYYIYAQAASLAIATIDAEMVVVATARLKYCRPAYLGEKIIARSKVGTHKGNKYVVSVHSRIGDREIFVGRFVVAALDAHNNEKLGDEIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFG5</accession>
    <name>A0A010YFG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_1128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442441.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1201"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_0"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="61"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="153"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="245" mass="25467" checksum="314EF93F55BADE52" modified="2014-06-11" version="1">MDKRIALVTGAGRGIGRAIALELAKDGCAVAVNYSRSEGPANEVAAEIRAMGGEAVAVKANVSDAAEVKEMFKLVAEQLGAVNILVCNAGITKDNLLMRMKESEWDDVIDTDLSSLFYCAKEAVRPMLKGRWGRIIAITSVNALRGGAGQCNYAAAKAGMIGFIKSLAREVAAKGITANAIAPGFIETDMTAVLSDELKGKFVESIPAGRAGTPRDVAGAAVFLASENASYIQGQVIAVDGGITM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFH4</accession>
    <name>A0A010YFH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATPase (AAA+ superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484919.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1214"/>
    <dbReference type="HOGENOM" id="CLU_041527_3_1_0"/>
    <dbReference type="OrthoDB" id="801313at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041682">
        <property type="entry name" value="AAA_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025420">
        <property type="entry name" value="DUF4143"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13173">
        <property type="entry name" value="AAA_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13635">
        <property type="entry name" value="DUF4143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_14" evidence="1">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4143" evidence="2">
        <location>
            <begin position="199"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="421" mass="47497" checksum="79794F125C9BFA58" modified="2014-06-11" version="1">MYIERAIEKSIIETDMSFPVVLLTGARQVGKTTVLKKLAQNSGRKYVTLDDPAARELASREPELFLQRYEPPVLIDEIQYAPDLMTHIKIYVDSHGDERGIFWLTGSQVFHLMRGVSESLAGRVGILNMAGLSNGEINGSVFSEFTTSPDILMTRLKSAVPMDLMQVYERIFRGSMPALYAADTDSEKFYYSYVQSYLQRDIRDLTQVADENSFYRFLCVAAARSGCMLNYEAMAREADVSAPTAKRWLSLLVTSGIVILIEPYFSNALKRAVKAPRMYFLDTGLCSHLTRWTSPENLEAGAMSGAIFETWVVSEIYKSFINTGRRPPLFYYRDSNSREVDLIIAKDNTLYPIEIKKSAHPVNASRHFKALLPEGEEKDSDNSGEIFAVQNFNLGEGAVICMSQDLLPINKHNWLVPAWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS73</accession>
    <name>A0A010YS73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline-glycine betaine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484760.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.81"/>
    <dbReference type="HOGENOM" id="CLU_010118_6_3_0"/>
    <dbReference type="OrthoDB" id="1217683at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG77968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="543" mass="60271" checksum="0FF3177EE70659B1" modified="2014-06-11" version="1">MKNIRSTVLFVPSAIFIIVLIAGFIDIKTFNSVLTGVFERLMVNMGWLVSLTMLVFVIFCLTMLFHPIGKIRIGGPNAKPKMTRWQWFAVSLCAGIGTGVVFWGAVEPLLFTMQPAPSLGIAPGSNEAVIWAMSTTFLHWTLTPYAIYVTFGVILAYVCGNMRKPFNPSSGFVPLIGDRALSRKFGDIVDTFSIFALAGGIAGSLGYGILQLSRGVDIIFGIPSSTFIYCLVAAAIVAFYTLTCISGLKKGIMWLGDQNGQIYMVLLFFMLVTGPTAYIFNLGTQSTGTYLQNFIERMTYTAPFNNAELWPQWWDMYWWVDWLSYGPIMGLFFVKLSYGRTIREFVTVNWLLPSIFGIVWFSIFGGTVLHAQLFEGADLFALYKAKGAEILTFAAFDYIPFSVFVKPFMLIVIAISFVTLANSMVATISLMSMRNNLGVEEGPTSLKIYWGLMLGSVSLLFTLSGGIDGIKMVKTFCGFPIMFMGLFMVYGFVKYMGKRPRDAYGNYLYEDAVADAPDSGEPMAKQSAVMRKLSKLFGIEIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSC6</accession>
    <name>A0A010YSC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.147"/>
    <dbReference type="HOGENOM" id="CLU_035307_0_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="473" mass="50237" checksum="9C6F1EF9CB6515F6" modified="2014-06-11" version="1">MENTSEKKTKLKALNPIVLLAIILVIAAIATYIVPAGVYERVMDPTTQREVVNPQSFKYIAQHPVGFFEFFMSITLGMQRAAYIIFFLFLVGGAFGVIEATGAMNACLASVVKRMDGRELVVIPVCMIIFGCGSAFAGNFEEYLVFVPLMIAVCVAMGFDSLTAIGVVFCAAASGYAGAMTNPFTVGVAQGISGLPMFSGIVFRAGVFIALITASIIYVMLYARKVKNNPELSSVHEIDLEYNSHTHAAIAEAQSKGMTTRHKLVLLTFVAAIAVLVYGVLKLGFYIDELAALFVIVGIVAGIAGGLKAGEIADAFLKGCDNMLFACMVIGLCNAVIIITENASIMDTIIHSLSRLLNGLPPAISACAMFVVQDIFNVLVPSGSGQAAITMPIMAPLADVIGVTRQTAVLAFQMGDSFTNVLAPTSGEVIAAIAMAKIPYGKWVKWLLPLFGIWCLIAFASLIIAVTVGYGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSF8</accession>
    <name>A0A010YSF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 7">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0173</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + L-glutamate = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709277.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.186"/>
    <dbReference type="HOGENOM" id="CLU_019582_2_2_0"/>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006536">
        <property type="term" value="P:glutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="PTHR43321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="463" mass="52229" checksum="432D7CB6A21D0FA9" modified="2014-06-11" version="1">MSLYQKEYEHREIDPTFGSAAMASLLPKNAFPEAEMKAQDAYQAVHNELVLDGNASQNLATFCQTWLDEETHKLMDECIDKNMIDKDEYPQTAELEARCVRMLGNLWNSPEEANTIGTSTTGSSEAAMLGGLAALWRWRKKRKAQGKPTDKPNIVTGAVQICWDKFARYWDIEHRQIPMKPGKYCMTPEEVGKYVDENTICVVPTLGLTFTLQYEPVKQVAEALDKLQKETGLDIPIHVDGASGGFIAPFIHRDLVWDFRIERVKSINASGHKFGLSPLGVGWVMWREVSDLPEELIFYVNYLGGNMPTFALNFSRPAGQIVSQYYNFIRLGREGYSKIQQECAETGQFLAGEIMKFGIFEMVYDGDGGVPGCTWKFRDDVKPGFSLYDLADKLRSRGWQVPAYSLPADAQNVVVQRILVRKGFNIDMASLLIEDMKRALAYFKTHPVAKPLTEAETGNFKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSG2</accession>
    <name>A0A010YSG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1060518_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="262" mass="30737" checksum="811CF314AF5C12E1" modified="2014-06-11" version="1">MKGLSIMSGRSCILWCSMIALFVFPAVPLASDTKPRLRASSFLCHDFSDAPQSRFVEMSDKAFGRECEKLRKELEDSYNAYYMMLDDGGRRELFESEVFWEKYLRCYQKNLCDTLDRPLLIFTGEAKSPVITNVYREIVTDILRWRINDLKRWEKGRYLSNANNSTEDIERKLSGERRRYTQLKSDAVLLRYVLYHYDRRNMDKTANLFGEKKLDFLENRTSDKRTLLCEQLEMRTRGNRVLEMISAGLRGVAPVIREEGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSH8</accession>
    <name>A0A010YSH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sugar diacid utilization regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0193</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441370.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.212"/>
    <dbReference type="HOGENOM" id="CLU_043769_1_1_0"/>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008599">
        <property type="entry name" value="Diacid_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05651">
        <property type="entry name" value="Diacid_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diacid_rec" evidence="2">
        <location>
            <begin position="3"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF_2" evidence="4">
        <location>
            <begin position="143"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="3">
        <location>
            <begin position="344"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="412" mass="46457" checksum="88E6B624AA53CACB" modified="2014-06-11" version="1">MLSKYAQEISEYLSSMMGRSIIITDINGIIIGSPAKERIGDFHPSSIPCVKYKKMSFDDAKAAKELGVWYPGSTVPLFYNGRVIGTAAIAGEPEVVMQFSLLVKNQIESMLREKILSPSLSSPQKKINELVRDIGVFDPNRDDHALLTKRAEQFGIELDQPHGVIAVFFSNFRGLGLEKNPVKISYESYSDPIEDEIDYSSMHGRVIVLLREIFPDPQNIIASVARDRFVVIRPCDIDEKHLEEDIEASCESAGEIYNKLKDASLETIIGVGHPAHNLFELPNAYRNAWDVVGIAEKLSMPPGAYTFDRLLLEEMLISVKPHFSLRFIEKRLAALGGDGDAHDLLDTFKVYCESFFSKQQAAEKLHLHRNTLSYRLQKIEERLGISMQDFKQVMAYYLALYMKELGNRGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSR6</accession>
    <name>A0A010YSR6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multidrug export protein MepA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.306"/>
    <dbReference type="HOGENOM" id="CLU_012893_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="460" mass="49301" checksum="FE7AEEA8778B081D" modified="2014-06-11" version="1">MINSAVSKEEQHRRMGSEPIPRLILSFALPAIIGMIAGAIYNIVDRIFVGRYVGSVGLAAITVSFPMMMMLMAFTLLICVGGASRVSILFGANRRRPAEQALTTTFVLLAIVGAASIAASFFAVDAMLRLSGASGEVLEMARPYLRIILLGAPLGLFGFGANFLVRASGNPRFAMCTQIVGAVSNVILDAFFIITLDMGVAGAAYGTVLAQAVSAVFGLSFFWRREAPLRIRAHFIGLPRWDVFKRICAVGSAPFFMELSFVCYMTLMNQLIIKYGGDAGLSAMGIFLSLDSLLFLPAMAIGEASQPIIGYNYGAGMPKRVIKAIYCALGMAVGFYVISFTLAEIFAGPMMRLFTNDEALLAIGVPGMRVGYIGLPFMGVTIVTNSALQGLGKGFASLALSFCRHVLCMFIPLIMLPRIFGLLGVWMSFPCGDVGGCVISLGFLVWTIRWLKSPAALAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSW0</accession>
    <name>A0A010YSW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441514.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.358"/>
    <dbReference type="HOGENOM" id="CLU_060077_8_3_0"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="140" mass="16187" checksum="725BB94E7E6F2981" modified="2014-06-11" version="1">MTISEAAEKTGLSADTLRYYERIGLIPPVPRTESGLRDYNDEVIEWVMFIQRFKEIGMSLESILSYVKLAMLGSGTRQERKVILLETRRSLMSKIEHLHGCLREADYQLEHYDSGLMTETENAVGRWRRREEVSAQSFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT27</accession>
    <name>A0A010YT27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709110.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030705_2_0_0"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="8"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="366" mass="39230" checksum="7ED5A09556C99189" modified="2014-06-11" version="1">MKNAYETDLLVIGGGAAGLCAAAEAAAAGAKVTVIESDLHPGGQLVKQTHKFFGSKDEYAGTRGYKIADILLGEIEALGDKVNISCNSTVTGYYPEDGLFTVMEGEDDYYRVKAKKTVIATGAQERMIPFTNNDLPGVYGAGAVQTLMNVYGVVPGKKVVMVGAGNIGLIVSYQLRQAGVDVVAVVEAMPQIGGYWVHAAKIRRLGIPILLRHTVTKAVGDKVLEGAVIQELDDKFQLIGEPKKIDCDIICMAVGLTPTTELFWQAGCKMQFVPQLCGYVPFRDKTMRTSNPDIWVAGDASGIEEASAAMVEGRIAGHSAAKALGLPVDDKRFGEYWERLHHLRAGEVGQKITAGVNQVLVDKWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT73</accession>
    <name>A0A010YT73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441707.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2896093_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="62" mass="7057" checksum="B3563F82AB3BCDAD" modified="2014-06-11" version="1">MKLEAVYQQEAHNQLYNIAIEDRDELVGAVAKIKGARDFVQSVRRWKGQAEAIVSAEERNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTH2</accession>
    <name>A0A010YTH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441849.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_0"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="255" mass="27063" checksum="22C07B70BD1FBBFE" modified="2014-06-11" version="1">MDLLQKYSLAGKVAVVTGSAQGLGKGYAVGLAEAGALVVCADLNFGGVEKTADEIRGRGWSAEAVRLNVTNPAEVNGIFQEIVSKHGHLDILVNNAGVEDISPFIKVTEAQYDKIMGVNLRGAFFTAQAAARIMKGQKSGKILNIGSLGSAIGLSESSVYCGTKGGILGITRTMAIELARDNVQVNAIGPGYFRTPMTEPFFQDPQHKKWIEERIPAGRVGVVEDLLGTVIFLCSRASDYLTGQIIYVDGGWLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTK4</accession>
    <name>A0A010YTK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate/oxaloacetate carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710374.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_4_2_0"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="523" mass="57637" checksum="399586FEEEC28B50" modified="2014-06-11" version="1">MSEVEIKKEIKDSNGKVIATKVTTGAAGAAPTVEPAAEAVKPEQVVVTENKKPETSAAKTKPRVGIMETAFRDAHQSIMATRLRTDDMLPICEAMDEVGYHSIEMWGGATFDSAMRFLNEDPWERLRQIKKRLKKTKTQMLLRGQNIVGYRHYSDEVVREFVKRAIGNGIDIIRVFDALNDLRNMSIAAEAVKKEGGELQMTISYTISPVHTLDLFAKQARDMADMGADSICIKDMAGLLSPVAASALVKAIKKKVSLPVQIHSHYTSGMAAMSYMAALEAGADVVDCAISPFAMGTSQPATETIVAALAGGPLDTGLSLEKLLPVAQYYQMLHDKYNDIIMGVSGVNINILLYQIPGGMYSNLQSQLKEGGCLEKFKEVMEEVPRVRKEMGYPPLVTPTSQIVGTQAAMNVISGKRWKMVPNEVRQYFRGYYGKTPAPVDPEIQKLVLGDEEPITCRPGEKIAPEIEQAKKEIGMWCTQPEDILSYILFPQVAKDFLPNKFARENLVDIGQEPQEDPEAYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTR4</accession>
    <name>A0A010YTR4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AcnX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441941.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.735"/>
    <dbReference type="HOGENOM" id="CLU_018825_1_0_0"/>
    <dbReference type="OrthoDB" id="421985at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007506">
        <property type="entry name" value="AcnX_catalytic_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04412">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcnX" evidence="1">
        <location>
            <begin position="1"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="43178" checksum="20E136F22F0CA487" modified="2014-06-11" version="1">MRLTERENSILRGAEGEGAALAMEILAGIGEAMEADVFVPVARAHVSLSNQEADLWFAEKMLAGGSRARICATVNPGFDIDYFGGGGFASDRDVKLTERCRAAYKEMGFILNFTCTPYLDGNLPRLGENVAFSESSATAFVNSVVGARSNPESAQSALCSAIVGLTPRYGLLLEENRRASVYVNVEREIADEFDFSLLGWAAAKKIGRDVPLFRGVFRASTEGLINLGAELNTAGRVPLFHVEGVTPEAEFARRGTGTIRELTVTDRELAEAEEKLLGTAAGAEGVILGCPHYSLSQICLVHRRLAGRKAGIPVWILTSAAVAAQISRLPMGKDLKESNVTVIGDTCVDQPCWGFLRGKRLLTDSPKCCYYTARRELNFSVMPLARCLDAALGKEAECNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTS4</accession>
    <name>A0A010YTS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441953.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.748"/>
    <dbReference type="HOGENOM" id="CLU_049749_4_0_0"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="47"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="250" mass="28503" checksum="F66B32F1EF96739D" modified="2014-06-11" version="1">MKENKYDDGVFFEKYAGMKRSQEGLAGSGEWETLKKLLPDFKGKRLLDLGCGYGWHCIYAMEQGAAAATGIDISEKMLSVAREKTRCPEVTYMCMALEDMDFPAGSFDIVLSSLALHYVESFDEIAKKVNRFLSDEGYFIFSAEHPIFTAEGSQDWYRDGAGNILHFPVDNYFYEGMRRARFLGEEVVKYHKTLTTYIDGLLTNGFELLRVAEPQPPERMLCIEGMKDEMRRPMMLIAAARKKLSLRNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTX5</accession>
    <name>A0A010YTX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441998.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.802"/>
    <dbReference type="HOGENOM" id="CLU_081837_0_0_0"/>
    <dbReference type="OrthoDB" id="1515029at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="214" mass="23012" checksum="30AE28B1264E1029" modified="2014-06-11" version="1">MENINNEPKVTWASYVALFIVVIMFSGIFANSGGILKAFDFSQLNGQFGNIPFEKGFNFKGVGGSGARDGFMMAITLTPAVILALGIVSVCEGFGGLLAANRLMSPFFKPLLGIPGICGLAFIASLQSTDTGAGMTKELFDNNFITDEERSIFCQLQLSAGATITNYFGSGAAFFPFLAVPLGIPLLMVFIMKIFGANVMRFAIRWDLKRQAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTY6</accession>
    <name>A0A010YTY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRISPR-associated endoribonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442014.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089858_2_0_0"/>
    <dbReference type="OrthoDB" id="908607at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010156">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045747">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36984">
        <property type="entry name" value="PTHR36984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01881">
        <property type="entry name" value="Cas_Cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005054">
        <property type="entry name" value="PF1131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01877">
        <property type="entry name" value="cas_cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005054-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005054-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="250" mass="28029" checksum="CB3FB0003E10B3C1" modified="2014-06-11" version="1">MHISLFINSHESRVLRLPCSNLHLFQSLIYKLLPPDRAAFLHDQGYIIDNRPLKLFAMSWPIAEKPPRLAGGFLEFDLPIRLVVSTPITSTMDGIASGALMNKYMHIGANTVCCERVEVNCYNAASDEIMIRTLSPISCYSQMLRHDGRKYTAYFSPFEKDFSNSIHNNLNRKFRAIHTAAEVPEGVVEILPIGVPKERVAKFKEDNSFPIKGWEGRFKLKGPKELLQVALDCGLGAKNSLGFGCIMPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU63</accession>
    <name>A0A010YU63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, Spx/MgsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442054.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.878"/>
    <dbReference type="HOGENOM" id="CLU_116644_2_0_0"/>
    <dbReference type="OrthoDB" id="1606021at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006504">
        <property type="entry name" value="Tscrpt_reg_Spx/MgsR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01617">
        <property type="entry name" value="arsC_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="117" mass="13363" checksum="F6CD02CDE11087DB" modified="2014-06-11" version="1">MLLLCYPQCTTCRKAKNWLEEHGVEYTERNIKTENPSAGEINSWRKLSAQALKKFFNTSGSSYKELGLSKRLPELSEDEQITLLAADGMLVKRPIAVTEDKVLIGFKAEEWEKELAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUI5</accession>
    <name>A0A010YUI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442240.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131578_0_0_0"/>
    <dbReference type="OrthoDB" id="1958018at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="144" mass="15879" checksum="EFEFC9A455379972" modified="2014-06-11" version="1">MIAGIDPGRWKIGVAFVEGKELLFSAIVPAEKRAVLISAFEAGEWGPLGEWRMEGAVKNLAGRRAEKICIGDGTSSKEFAKDFPFEYSETDEYGTTLEARKIFWRLHPPGGIMKLVPLSLRTPPRNIDDLAAYAIILRAEGSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGP8</accession>
    <name>A0A010ZGP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">recF</name>
        <name evidence="6" type="ORF">Cloev_0003</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RecF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.4"/>
    <dbReference type="HOGENOM" id="CLU_040267_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA_23" evidence="5">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="355" mass="39278" checksum="F1B445BE3F9F4B76" modified="2014-06-11" version="1">MGFSRVRFNNFKNLEPREMRWSPGLNLLTGENGAGKTNILEGINIISGWGPLERGTKALSMPTWGSGSSDVQLTGELESGGIIRVKISRRYMLRLDDKAVTAADLRWNIPVLTFLPDDMSIVEGSSVFRRRLLDMLLALILPSYAMRLAEYRRGVRQKAFFLKRGMPAMIADRALLPLASWIWRMREEGVKLLSSCLEGMSELTPARITLSLKRGGAGFDDDCEDDYTKAVIANRGREAAVRFPVVGPHRDDIMITAGDRPASEALSRGLRRRTAIALMLAAADGVKRKIGRDPVLLLDEVTAELDSSGRSLLFEALLSRGTQVFAATAEPFCENFPGLIHKVSGGRITESRENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGR7</accession>
    <name>A0A010ZGR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708527.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.28"/>
    <dbReference type="HOGENOM" id="CLU_026228_5_1_0"/>
    <dbReference type="OrthoDB" id="1222928at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027141804" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="30"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="274" mass="28819" checksum="D7769D039D85261C" modified="2014-06-11" version="1">MKKFLIAAVICLFAATAFAASPLDVFKGRKGKIDIAGGTAHIPVMKEAAKRIMGVNPDIRITVAGGGSGVGVKQVGEGLVEIGNTGRPLKKDEVEKYGLETFPFAIDGVAVVVNPANKVAELSFEQLIDIYAGKITNWKAVGGDDAEINLYVREDGSGTREVFTDKAIKKGDVSAKANVVNSNGAMKTAVAKDARAIGYVGIGHIDSSVKAPKLAGMTATQENAASGKYTVVRDLFMNTKGKPAGLTALFIDYIYSPEGAQIIKDSGYIPLPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGS2</accession>
    <name>A0A010ZGS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycine/sarcosine/betaine reductase component B subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441215.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.35"/>
    <dbReference type="HOGENOM" id="CLU_050376_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050485">
        <property type="term" value="F:oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015417">
        <property type="entry name" value="Gly_reductase_pB_sua/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09338">
        <property type="entry name" value="Gly_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="435" mass="47087" checksum="3E5A0C9554E13761" modified="2014-06-11" version="1">MKLDFHKLYIKGLEWGEKTTVSDGVLYVNKEEAIQACGVFPAVASFSLHIARPGESVRILPVKAAVEPRCKLSRQGSMFPGIVGDMEQAGIGETLALKNCAVLVTESGDKEAKCRTGGLVDMSGPAAAYSPFSKTFNVVLCARVKPEVLKEETLTTDEACRLASFRLAVYLAQSCSDARADEVRTYELGKADERLPGVVYVMQLLAQNPEIIDFHVYGQLAGTTLIPTVVHPNEVLDGAVTTFLGAHCTVCADKQYMYEVQNSPVIEEFYEQHGKKVRFLGVIVHNEVTTMEGKLRASAFTAKLAKMMGASGAILVTEGHGNPDEDIMLNVKALEDEGVKTVIISDEMGGRDGRSPGLADWVPECGAMVSVGNMHQLLAVPKALETFIGNEDSMDIIRAVIDSHPEDSGLFYTELIHIPCSCAQAGISRLSADWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHB2</accession>
    <name>A0A010ZHB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uridine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709328.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.223"/>
    <dbReference type="HOGENOM" id="CLU_023775_1_0_0"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TGS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="546" mass="61559" checksum="0D593EA96A8BE6EC" modified="2014-06-11" version="1">MSMEIKFKDGDPLVCEGPVTARDAMEMINFPKRENVVACRVNRVQRPLSWEIVMDSFVEFITTDSIEGIEVYIRTLSFLLTSAATRIRGMRLSLTQSMSYSYYYESPDGEITEDICRELEAEMRRMVDEGVPITRESFPIDVARAVMHAQNYEDKEQLLLFAGSDPVIVYNCCGVYDFFGGALADCAAITPTFELRHYNGGIFLSGPTFADPTKTMAFVESPRLFKLIDSHTDWLKNLHMSTMAGIHRQVTDGRSRDMIMVCEALHTKLLSNTSAQIEARPEVRLLCLAGPSSSGKTTSSRRLRVQLLSSGIKSATLELDNYFVDREHTPLDREGKPDFEALEALDLELVNEHITALLAGREVDIPKFDFLTGKRTKGYKMRISPDELLVIEGIHGLNEKLTASVPADKKYRIFICPLTGTNIDFHNRIGTTDTRLLRRLVRDARTRGHSAEATLMQWPSVVRGSHRHIFPYQEYADTLFNTSLAYEVPVLKGYVTPLLKTVKEDSPVYGEATRLLSFLEYVPVIPSDDVPNLSVLREFIGGSCFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHB8</accession>
    <name>A0A010ZHB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441385.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108058_0_0_0"/>
    <dbReference type="OrthoDB" id="1538470at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459047" evidence="1">
        <location>
            <begin position="27"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="206" mass="23702" checksum="49EB8D85D2822F91" modified="2014-06-11" version="1">MKLKKITMIAAAAAILVMALALQALALDFSAEFVEKDGDSVRKGKIYMTGQKSRFEMEGMDSIEVTRADKKVMWIIFPKKRVYVEEEFWGVIPGDVKETNAAKDTGDLSRKDLGYEMVDSYRLKKFLVTVKYNKGETQDQYYEWHRSGFPIPVKMESLNGSASYEYQKIKTAPQDPNLFNEPKGYKKITIDELEKLEAEWAKEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHE9</accession>
    <name>A0A010ZHE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyrroline-5-carboxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484796.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1018818_0_0_0"/>
    <dbReference type="OrthoDB" id="1417374at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="25"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="287" mass="30242" checksum="F731B3BBD248CCBD" modified="2014-06-11" version="1">MKNINDRNTATAGCLTDEALMGKTLGVAGFGHLGSSVVSSLLAHGFPKERLLISCGGRAETLERARAAGLARCMTKTAELMGRSDIILLAARPQSLTDFCGMAVKKGAFIISFMAGISLETLHRVFSADLCRVMCSGPETIADGLGLGVSFPSEARSCAVLKAAGLKVFDLSCESELDSFTVGICLPPILLNTEVDEDEKRSALLDMSKRYPIYRELAPWIDRVTAAHAGEKSGASLTNVSTKGGVTEAMTTALREGASFSEALVAGLSRNDELCAGLRRKFAVSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHN5</accession>
    <name>A0A010ZHN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441488.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.341"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_0"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="292" mass="33581" checksum="80ADEBF5CF38F4A8" modified="2014-06-11" version="1">MELRLFRYFLAVAKEQNITKAARVLCVTQPTLSRQLSELEAELGTQLLIRGKRKVTLTDKGSLFRRRAEEIVMLADRAEQEVKTPDYLAKGDIYIGCAETETMRIVAKTAKELQQDYHNLCYHLSSGNAEDLRLRLEKGLLDFCVLMDPFDKRDFNYIELPGKDVWGLLMRKDSLLVSHERITAAELKDLPLLVSQQEEQSAEGLKKWLKGRELNIVGTYNLLYNTTLMVEEGMGYALTLDKLAPTGNDSVLCFKPLYPAVETSSYFVWKKFQIFSQAAKIFLNKMRETYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHZ3</accession>
    <name>A0A010ZHZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcriptional regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709140.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_39_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024187">
        <property type="entry name" value="Sig_transdc_resp-reg_cit/mal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45526">
        <property type="entry name" value="PTHR45526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006171">
        <property type="entry name" value="RR_citrat_malat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="231" mass="26568" checksum="3D4C564ED5969E64" modified="2014-06-11" version="1">MRSLKVLIAESDPLLQKLYSDIIINDSAFTLLKCVSTGPQMFEAMRCVDVDLVLLDLFLKDFSAIEGLDDLRKSFSRTDYIVVSSGENPELVRKALCAGVFEFLVKPFSFDRLRATLKNYQIYHHSLTGRTRPWQQEDLDALVSMKSHDPSWANNRSIPKGLQLKCLNDIESFLKANEDTFSAQEVGEHLGISRSTARRYLEFLTMSERVVVEYAYRRVGRPEKRYRMALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI00</accession>
    <name>A0A010ZI00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0445</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484828.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_0_0_0"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075713">
        <property type="term" value="P:establishment of integrated proviral latency"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044826">
        <property type="term" value="P:viral genome integration into host DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038488">
        <property type="entry name" value="Integrase_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025166">
        <property type="entry name" value="Integrase_DNA_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13356">
        <property type="entry name" value="Arm-DNA-bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1179">Viral genome integration</keyword>
    <keyword evidence="4" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="7">
        <location>
            <begin position="100"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="6">
        <location>
            <begin position="202"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="418" mass="47997" checksum="291D10FF0B7B7D8E" modified="2014-06-11" version="1">MLTELQARNAKAESKVYRLKDEAGLYLEVRPSGKKVWRMRYWIAGRERILTFGDYPLFSLKEARDRRDIARRIIADGGDPAEKWAEERAAVKAAEEAAKDTFEAVALEWLDMRLSENLSDRYKHKTEWRLRKYILPSIGKIRFSEVSPLDLLGMCKALEARGLVETEHRLVGICSQIFRYGIIWQKRTDDPTYSLRGALMSPTVRHFSSIQDKSLLGEFYVAIESCTGSEIIKAALRFLVLNFPRPGELRHAEWSEFDFDTNMWSVSAEKMKMKRPHMVPLGSHSLALLKALHPLTGHGRYVFPSPRSGTGSVPLSDMALNVAMRAMGYEQEDVSAHGFRHTASTMLNDSLLWSPDAIERQLAHVDGNKVRETYNAAEYLEERKRMKQWWEDFVIGEAEAARKRAEKKKKEREQKGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI33</accession>
    <name>A0A010ZI33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1479613_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="182" mass="19993" checksum="C449CEDD9F1A102E" modified="2014-06-11" version="1">MGKVNAAEPEETDVLAFLNRALEGIWNYGARLNSPVLFRHEVFTSPDGGTVQILGGAMKVRSVRDCDSGLLLPSVTLDYAEAAPLASGRRCYVAYPARVDIYPLDMPVTAEITYLPFFSRIKDRADELPFSPELDNSVVALVVGMMGGAEPDELMSRVRYGNAVSRYFRPRGADCVVCRGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI67</accession>
    <name>A0A010ZI67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.560"/>
    <dbReference type="HOGENOM" id="CLU_504952_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458313" evidence="2">
        <location>
            <begin position="32"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="3">
        <location>
            <begin position="274"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="444" mass="47765" checksum="70A50266CD0EF3B9" modified="2014-06-11" version="1">MLSLRVNNRIFTGLIAVFASLFILSASCAFAAETLSFWNGEVKKGDVAARRNGTIQEVAIDEVVSSLGFIPKVDASSIIVVLEGKKIEFWNASNVVRAAGSIISFPLPVSNTDGHWWGDAKSVAAAFGYFYAAIGKPSAFRWGEPSAAPQPPVQPKVSEPQRPVEEKPAEPEKRPVVKIPSAEPAQPPAAQKGEPEEKYTPAAPVATFSGNKRPVVVVDAGHGGHDPGAAANGVREKDVNLKAAIELGEILRQYGIDARLTRRTDVYLKLAERTAFANKNDADVFVSLHCNAMPKGRSSVAGLEYYIMALPSDKDAMNLAIAENKEISAGVDSAAEAQRADKKTQLLLKILGDMQQNDKINESTTLAEVMHKAAKAGSMPMRKVAQAPFFVLRGAGMPAVLVEMGYLTNAAEARKLNSASYREALCRSIAQGIVQYIKEHPTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI84</accession>
    <name>A0A010ZI84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC-type transport system involved in Fe-S cluster assembly, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441787.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.577"/>
    <dbReference type="HOGENOM" id="CLU_026231_0_1_0"/>
    <dbReference type="OrthoDB" id="635721at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="391" mass="43062" checksum="B933530C07C9D9AB" modified="2014-06-11" version="1">MKEEFRVDEHLDDFRADAPVHDEIKNIAELPAGDRERLLRAGIDDEEKAAGTFVHADHNTVYCNANLKGVELMPISYALFKYDGLKDYCWKIIEKEKDPFTELAAKRSEGGYFIRTEKGAKVDYPVQACMYIETDALAQDVHNIVIAEEGSELNIISGCASGPNVRSGLHVGVSEMYVKKGATLSFTMVHDWAEEMSVRPRTVVVVEEGGRYISNYICLKPAKDLQMYPTVYLNGEDSVATFNTVLMAGPGSKMDTGSRVYLRGGGSRAEIVSRTVSTGGDIYARGHLIGEEAGVKAHLECNGLLLSNQGKIHAIPELEARHKDLEMSHEAAVGKINQEETEYLMARGLSETEAQSLIIKGFLSLDILGLPELLRKDVERTIEESTAAGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIB4</accession>
    <name>A0A010ZIB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotidyltransferase/DNA polymerase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0577</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484843.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.617"/>
    <dbReference type="HOGENOM" id="CLU_012348_3_0_0"/>
    <dbReference type="OrthoDB" id="442163at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="3">
        <location>
            <begin position="9"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="442" mass="49254" checksum="7E21E185654A7CD3" modified="2014-06-11" version="1">MEDMASRAIGLCDCNNFFVSCERRENPALIDRPVVVLSGNDGCIVARSNEVKAMGVPMGEPYFKVRGLLERAGAAVLSGRLSLYNKISAEVMSRLACFSDVTEVYSIDEAFINLAIPSIKDPAAYCMELRKDIWRHCSIPVSVGISSTKTLAKLASHCAKHSDSGVFWLKRDSYADPRWMAQFEVGDIWGVGRRMAKRLNLYHRILTAADFVSADDLLLKRDFSVNALYTAWELRGYPVYPLAGGRRAPKSIQVSRSFGEAVFSYDELQEAVSYFTLCAARQLRAAKQRASRMGVYITTSRFRTDNFYAREDARSFSSPRSLDCDFLSAARDMLAGIYREGCAYKKAGVVLDDFTDVSCGVQQLLFDEEGRPAAREGKFLLAAAVTDSLNREFGRLVIGSADNFGAPERKSKWYPRRGHSAAENDYRDRPALPIGPSRRVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZID4</accession>
    <name>A0A010ZID4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oligoendopeptidase F</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0597</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has oligopeptidase activity and degrades a variety of small bioactive peptides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484847.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.637"/>
    <dbReference type="HOGENOM" id="CLU_021290_2_0_0"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004438">
        <property type="entry name" value="Peptidase_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00181">
        <property type="entry name" value="pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="127"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="216"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="609" mass="69574" checksum="1577518B1388BED5" modified="2014-06-11" version="1">MAIEKNTELELGRGASLPERSKMPEDYKWRLEDIYPSQEKWEEDFAELKARLPEISAFKGTLAESPAQLAKLFALRDELSITLGKLFVYANMKSHEDTADSKYQGPANRVSVLSVEFSACASYVTPEILEMPHERLEEFARAPELADYSFSLRELLRQRAHVLSEAEELILARTGDMAGTADNVFSMLTNADMEFPSIRDEKGDKVEMSEERAVSYLRSPKRQVRKAAFESLYKPYAEMKNTLGATFDGMLKSSKFYAECRKYESPLAEALDANNIPLSVYDSLVDTLENNLAPMYRYMELRKRILKVKELHMYDLYVPLVADSFKEIAWSDAKEMMYRYLAPLGGEYLANVRAGLDEGWADIFPNRGKRSGAYSWGAYGTHPYIFMNYTNNLNDVMTLVHEMGHSMHSFYSRRSQPYATADYCIFTAEVASTTNEVLFLSGLLSETEKKKRRLYLLNRRLENIRTTVYRQTMFASFEREAHLRAANGGDTTPDGLKELWYELNRKYYGETVIIDEPLKMEWARIPHFYSPFYVYQYATGFSAATALAQAVLAEGAPATERYLNFLTKGGSDYPIELLKGAGVDMSTPEPVKAVVKQFEETLDEMEELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIK0</accession>
    <name>A0A010ZIK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell wall-associated hydrolase, invasion-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.706"/>
    <dbReference type="HOGENOM" id="CLU_045651_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027017">
        <property type="entry name" value="P60_peptidase_YkfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039439">
        <property type="entry name" value="SH3b1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12913">
        <property type="entry name" value="SH3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019015">
        <property type="entry name" value="P60_peptidase_YkfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3_6" evidence="3">
        <location>
            <begin position="145"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="306"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="442" mass="48150" checksum="435B1005AADA7398" modified="2014-06-11" version="1">MAATILLCLTGASFASENICGTTKEMMNAEFWVNGTKTAHETILAPAEVQALTSKIREAPGTFCTDILDYPDFLSREEFARKIKSYAARPDNKRYVGAAEADGEFWRRVESNANPGAADETTLVRFGAVVNNCLVKTLPCEEPLYSEADDVLFDMNVESAVKIWEPLAVLHESADDKYYFVESPYCAGWIKKENVALTDRKTLKELAAHDFYMVTGSRVTSDVRTSAPDAGRREFFMGTRLPAADEEESIGGVSAIFGHGVLVPERGADGSLRVVTDLLPRGADLSRGCLPYTQANVLKQAFKMLGERYGWGGMYGSRDCSAFTRDIYLTFGIELPRNSLPQAKAPAGNIDVSKLTAAEKAKLLAGAPAGTLVQMPGHIMLYLGTIRGRPYIIHSAYALGPSGKKGVEGVKTLNCVAVTDMEMTRRNGTTIIDNIANINIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIY2</accession>
    <name>A0A010ZIY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ethanolamine ammonia-lyase small subunit</fullName>
            <shortName evidence="4">EAL small subunit</shortName>
            <ecNumber evidence="4">4.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">eutC</name>
        <name evidence="5" type="ORF">Cloev_0767</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ethanolamine = acetaldehyde + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15313"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57603"/>
            <dbReference type="EC" id="4.3.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
        <text evidence="4">Binds between the large and small subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine degradation; ethanolamine degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bacterial microcompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.7" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442022.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.819"/>
    <dbReference type="HOGENOM" id="CLU_068224_0_0_0"/>
    <dbReference type="OrthoDB" id="1115166at2"/>
    <dbReference type="UniPathway" id="UPA00560"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009350">
        <property type="term" value="C:ethanolamine ammonia-lyase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031471">
        <property type="term" value="C:ethanolamine degradation polyhedral organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008851">
        <property type="term" value="F:ethanolamine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046336">
        <property type="term" value="P:ethanolamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00601">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009246">
        <property type="entry name" value="EutC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042251">
        <property type="entry name" value="EutC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042255">
        <property type="entry name" value="EutC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39330">
        <property type="entry name" value="PTHR39330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05985">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 4" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="2 4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="307" mass="33253" checksum="47DBE8956E2098F2" modified="2014-06-11" version="1">MVDQNMLKTIIEQVLTEMNLGNAAPVRSPAAAEVADVVKNSDGLTTESVVKVDDGFIPDVSAIDIRKQYLVETPLNRDAYYDLKQYAPARLGIGKAGARYKTLPVLEFRAAHSAAQDAVFSPMDLEFVEKLNLFVVRTMCTSKDEYLTRPDLGRKLTPEGVAMIKEKCKKNPTVQIFVSDGLSSAAVVANIPDLLPALMQGLQSYGIDVGTPFFVEYGRVGVEDEITEITGATVTCDLVGERPGLITAESMSAYITYKGTVGMPEARRTVISNIHKDGTPPVEAGAHIAEVIKIMLEKKASGTDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIZ5</accession>
    <name>A0A010ZIZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbon dioxide concentrating mechanism/carboxysome shell protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710679.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148498_2_2_0"/>
    <dbReference type="OrthoDB" id="1832681at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01614">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004992">
        <property type="entry name" value="EutN_CcmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036677">
        <property type="entry name" value="EutN_CcmL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36539">
        <property type="entry name" value="PTHR36539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03319">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159133">
        <property type="entry name" value="SSF159133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51932">
        <property type="entry name" value="BMV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="94" mass="9832" checksum="BC9B884D2E6DDD9F" modified="2014-06-11" version="1">MKVARVIGNIWATRKEQKLSGFTLLILQRIDITTGQDDGAPIVAVDLIGAGCGEMVIFVGGSSARSAAGDMSVPVDATVVAIVDNFELPGCKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ20</accession>
    <name>A0A010ZJ20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.848"/>
    <dbReference type="HOGENOM" id="CLU_017490_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016440">
        <property type="entry name" value="Rubredoxin-O_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005243">
        <property type="entry name" value="ROO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="254"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="403" mass="45112" checksum="CB43E65DAEC28A2C" modified="2014-06-11" version="1">MMQQAIKVTDSIYWIGGNDRETDLFEGLWELPRGVAYNAYFINDEKCAIIDTIKADKLSAYMERLVSIMPEGRSIDYLVVNHMEPDHSGSISILRKLYPEMKILGNKKTLEMIGAFYGITEGLVEVKEGDVIDLGRHKLTFAMIPMVHWPESMVAYETTEKVLFSTDAFGGFCALEGGIFDDELDMALYEDETLRYFANIVGRYSGPAQKAIAKVRALDLKIICPAHGPILRSNPRHIVDLYDKWSSHNTDEGIVVVYGSMYGNTKFMTDTIARAACEAGVKDVIVHDASRSNLSYIVRDIWKYRGLVLGSCTYNTELYPPMATLCRALKNKMMKNRVLGICGSYSWSKGALAELQVFAEQGGDWKLVEPTIEVKSSPTEADLELCRELGRNMAEAVKAAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJE4</accession>
    <name>A0A010ZJE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ig-like domain-containing surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0888</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.951"/>
    <dbReference type="HOGENOM" id="CLU_421458_0_0_0"/>
    <dbReference type="OrthoDB" id="2025779at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459115" evidence="2">
        <location>
            <begin position="29"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="353"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="433"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="762" mass="77492" checksum="01A12D9A75DD73A7" modified="2014-06-11" version="1">MIVGKLRKYGIIFLVLLMVLAAAPMAMAATATEIGQVNIGELFNEAGDYILSEDIVLSGDTKAIELSKDIEVTLDLNGHTISADTSKYRELESNALKYPGSIIYATSGDITIKDGVGGGKICDTSAAEYSKHNDGVIRVEKGTHLTIEKAIIEVKEGIGITTYDDGTRVTFKDGEIKVEYGFGIGTNGLNITEPGSGIYVEGGTITVASADSAAIYHPSSGTLSISGGTLSAADGIQVKAGRVIITGGTITATGKHNVPLDSKFSGGGTNELGNALSLISHASYKGQSMDVAISGSAMLIAEQDDAIGVYVNSGDVSHVNSFVITGGTYSSDPSAYVESPYVVKQVEGKYVVALASVAVTPTAAELVLGLTPTAKLTASSDIEEAFTWASKNNDVVTVDSSGNITAVGAGTADVTATGDSSKSVGTCVVTVRAATPVSVTPSKMELNIGATGKATAKYDAKDSITWESSDTAVATVKDGTVTAVKAGIAVITANGSKTSAACTVTVTDPAAPDPVTPTPAPVDAGTVDKENNPVNKEEGKPENVEAATPAITEATEEGKAAVVSATKIEEKNLVATADGKLTISPVLAKSALEEVISADATVAPKNVVLLPIVQAAVTANNVAALAFTMTGEQLGAEENTVAGDVKVIKVLADGKGGQFSYASAAADYADKTFTLKDADGKSLALTDKVAKASTYTLVVFVADNGDFDLDATAGSVIDPVAVATNAATEPKSGGSSSGCNGGFGALALLALAVLPFIRREKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJI8</accession>
    <name>A0A010ZJI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3134096_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="49" mass="5063" checksum="83CEF9A03A169C86" modified="2014-06-11" version="1">MSSQFYTIFAVILGSGVGYKLNFPAGAMVGGLLGIAHAGNGEVKKFKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJQ9</accession>
    <name>A0A010ZJQ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroC</name>
        <name evidence="9" type="ORF">Cloev_1040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711082.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1112"/>
    <dbReference type="HOGENOM" id="CLU_034547_0_0_0"/>
    <dbReference type="OrthoDB" id="981870at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="361" mass="37902" checksum="D7ABEFC9CAADB65E" modified="2014-06-11" version="1">MKFSIFGESHGPAIGVLLEDVPAGAALNMEEIAFEMGRRAPGKNALSTARKEADSPEVLSGVYNGFTTGAPLCAMIRNTDARSGDYSLLKRFPRPGHADYTAAARYGGFADMRGSGQFSGRLTAPLVFAGAVAKQLLARRGIFVGAHICSINGIKDTCLEDSPLFRSGGESLLRAAAHRELPVLDEGAGERMREAIAEAKRNGDSLGGVIECAATGLEAGIGEPGADSLESLISRNCFAVPGVKGIEFGAGFAFAEMRGSEANDPMEMKEGRVVMRSNNNGGISGGISTGAPLLFRAALRPTSSIAREQDTVDMERRADAKLVVPGRHDPCIVHRAVPAIEAAAALALLEAVQKLYGIRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJY7</accession>
    <name>A0A010ZJY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442445.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1508081_0_0_0"/>
    <dbReference type="OrthoDB" id="2124728at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="178" mass="19394" checksum="02F4B0E79CC2A562" modified="2014-06-11" version="1">MIVTVLILGGVLLTFAALALQTARAMFDEDTAAAGRLRIENAAAQASALAEEWFRVSIKDLAKENTFALSAEPQDDPTIELSPGFFQIMTEEYRSCGFSCQTIDLHYTDKFAASADKLRIPRIPPVELPDGSIERAYIQKVAVTPNENKNAAYTHTKSLRAIKDASGDIRCVVVGVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJZ2</accession>
    <name>A0A010ZJZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709815.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1213"/>
    <dbReference type="HOGENOM" id="CLU_1123368_0_0_0"/>
    <dbReference type="OrthoDB" id="1534863at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457955" evidence="2">
        <location>
            <begin position="25"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="252" mass="29065" checksum="433E57D8034B1094" modified="2014-06-11" version="1">MKRSVRMILAVACLLIGLAAVANAAATDQILSRWGKKIKLIDREDQVSNLEIRATYYSTEYVEALVQSEAQKNLWTQQEADEYKYRLLNTLQLEEMIPIRIEFTNNGPSMHLGPFDVMVKLMIGNKEYKMADYDKRFNFKFQGEKEGLVFFRRYDEKTGKDLLKGVKQVRLIFSPTISPITDGRRTEFIWDIANDDPAKLFQGKAAAKYETDRLIKRLEKLRKDKAEEEAKLASINGEISTIQARLDELAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL79</accession>
    <name>A0A010ZL79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein, putative Na+ channel or pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709213.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091659_0_0_0"/>
    <dbReference type="OrthoDB" id="1815957at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007563">
        <property type="entry name" value="DUF554"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36111">
        <property type="entry name" value="PTHR36111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04474">
        <property type="entry name" value="DUF554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0407">Ion channel</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="233" mass="24230" checksum="1E494571066CE28F" modified="2014-06-11" version="1">MELFSSIPLFGSIANAVFIVCGALAGLLLRKKIPAKIMELPVQGMALFVVTLGVGMAIKTQQPLVVIASIALGSLIGELMDLEGALEAASMKLENRIGDSAKGFSTGFITTSLIYCTGSMAVLGAFEEGLGGYPSLLLAKGLIDGLTSVAMAASLGFGVIFSAVPVFLYQGLLTLAAGWIQPFMSEAAVTEMSATGGLMLMGIGINLLGFMKIRVMNMLPGLIVAVILVRLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLA9</accession>
    <name>A0A010ZLA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441339.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1692426_0_0_0"/>
    <dbReference type="OrthoDB" id="5138at508458"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009936">
        <property type="entry name" value="DUF1468"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07331">
        <property type="entry name" value="TctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="155" mass="17623" checksum="EC3C8A2DD55D946B" modified="2014-06-11" version="1">MYRFIAPLFVPSVVLALSAAYYMESVNVDPIDKILIKPVCLSILAFYLYFIAVEYVRYKKRFQVPCKEGGADCHTKIKIPYKEMLIIGMTALYVWIIQYLGFVVTSIFFMAAMLYILNVRKLWVVCCFSVASSAILYIAFKVVLMVPLPGGILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLT8</accession>
    <name>A0A010ZLT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441491.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.346"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_0"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="280" mass="30334" checksum="C03BBF5AABE47D72" modified="2014-06-11" version="1">MKKRTWLITGVSSGFGYEMSRQLLERGDRVVGTVRGRDRVAALIEKYPDTFDCGLLDVTDVPAIHRFVDDAFRKHGRIDVVVSNAGYGLFGAAEELSDAEIDHIIATNLTGSIQLIRSALPHLRAQGGGRVIQMSTYGGQVAFAGNSLYHATKFGIEGFCESIAQEAAPFNIGVTLVEPGGARTEFRYGSAKVAKMMVEYEGNPAHAFLKMLDAANGLAPGDPVRMAARIIESADKEPAPLRMVLGSQALDRTISTLRARLADFEEQRELAASTDFPEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLV5</accession>
    <name>A0A010ZLV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709007.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079303_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="233" mass="26035" checksum="DD970FF181E2C259" modified="2014-06-11" version="1">MIKLPKIKLMDFIDPSESFLLAAILAAAGGFLDGYTFIGRGNVFANTQTGNLILLGVNLARGRIAASISYLIPVTAFLLGTYITERIRLRYSSLKHIEWRQIVVAAEALVLVLISFMPHYGDNVANAMVSFACAMQFDAFRSMNGVPFTSTLAMMNLRGAIEYVMDYREDRDMEKVSRSFEYLVTVAVFTLSVVIGSRLTYVYDDSAILFPAFLLFLGAILMFFRQKDKTRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLX2</accession>
    <name>A0A010ZLX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative regulator of cell autolysis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484812.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.378"/>
    <dbReference type="HOGENOM" id="CLU_020473_1_1_0"/>
    <dbReference type="OrthoDB" id="1031920at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="504"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="599" mass="66412" checksum="203A4426D0C03945" modified="2014-06-11" version="1">MERHLLLLRKAALCLAVVMTLLLAWRLISDKNSRVSVESLFVPVSLMGEYSVDGSPWLQLCSDADFGIKAGTTFFFRGNFSCEVEKNMLIMLRITDLYVEISQNGHRIYSFGEKRHPLFKSPGNLWHAFFSPGISPRDHIDIELRPVYGDDYLPAVSRFLNSIHYGSTDGLWRTEMHEYGLSFLIGVVTLVMGLLELAAAAGLVLLKQPLASRCLYGGGFSVSCGLWFAIQYGFISLIVPYPALIGSIDVLSFYFIGLFFILYIGTFLTGARKSVAACSSSFILTLIIGILVLALSGVRDAYDEPDLLVVTVVCGMLAALAAMWREYLFTCNRGLRTVFYTTLPVGIGIMADMFLFLRDGSENTIWLNAGVFVYAVVQWSFTIWQFKVNTDASVREEHMRGELAQSRIAIMLSQIQPHFLFNALATIKSLCVKNPKAARDAIDAFAKYLRGNMGSLNKNRLIPLESELLHLEHYLYIEKLRFGDRVNVEYNLKCRSFMLPALTIQPMVENAVKHGISLKPGGGTISVSTFEERAGFVVEVADDGIGFAPEMFKEGGRSHIGIENTKSRLKFMCGGSLAITSAPGAGTKAVIYIPKEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM21</accession>
    <name>A0A010ZM21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441572.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1903024_0_0_0"/>
    <dbReference type="OrthoDB" id="2172039at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458357" evidence="1">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="133" mass="14388" checksum="9FDECF969D2FFC26" modified="2014-06-11" version="1">MKRLFLAIVCLMFTAGSAYSCQPGAPKGASDKAAPDHVENEAIALVRVPPEMRAQDERRRLFGELCRKIAAGAGAEVLYISPIYEDSENGIAHMRSADKSAKELIALLKKDKNVIGASPNHITRLSPPIKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM56</accession>
    <name>A0A010ZM56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441646.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_5_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="38"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="251" mass="28108" checksum="4FC2E9AAC842D2C3" modified="2014-06-11" version="1">MTNQIWNPQEYRKSADFVSKLGEPVIELLEPKAGERILDLGCGTGILAKRLADMGCSVVGTDASPEMVSAAKELGLDVLLADAQTLKMDEKFDAVMSNAAIHWMPDQYAVVRRVWNLLKPGGRFAAECGGEGCVRIIREGMKIALIKRGIDYKARNPWKYPELGAFSKILENQGFQVKFIARIDRPTPLPAGLRGWLEVFSASHTAGFTDGERDAFYKEVEDYCRPTLYDEKKGWTADYVRLRFLAVKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM83</accession>
    <name>A0A010ZM83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441698.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1591662_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="18956" checksum="72FDA55B1E515A77" modified="2014-06-11" version="1">MSRKVSYIPKEVLRIEDIIWLFAEYCPTGLACFFGEAEFPAAEELSSMVAARYTPAADVGRIDGGQSTPQQQIVVESALSVKDILDSVGGLEMVRKVFILYGAEKPDKARILKEMSFIGRSFRYPSAEEFAYRNHMSPRQFYRCKESSIRQIAWEIYRRATLSGFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMF7</accession>
    <name>A0A010ZMF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0552</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441803.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.592"/>
    <dbReference type="HOGENOM" id="CLU_035307_0_1_0"/>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="473" mass="50703" checksum="D7216484109DD5DF" modified="2014-06-11" version="1">MKEPAEMSPQGQVKKKFLFPHIYVLLLMIIIACAIATWLLPAGEFERVKNAAGRTIVVAGTYHPIPATPVGPFQMIQAIYGGMLDAANIIFFIMIAYASIGLIIATGAFNGLVSGLLRIFKGKSRTVIIPVFIAILGVASSTIGVFEEAFPFVPIFVGIAIAMGYDAIVGLAIVACGVGIGYSGAVMNPFTVGMAQSIAELPPMSGAGFRIFCHISMVVVASIYTMRYALKIQEDPTKSLLYGSEMAAHVKADENLENYRFGIREILVLATLAVGIVVVVYGTKAYGWYLQELCAIFLIMGLASAAIMGWSPSETAEKVAASFADMAMAAMMVGLARAILVVLRAGSVIDTVVYGLAFPLSYMPSWIAAECMLVVQTLLNFLVPSGSGQAVISMPIMAPLSDLLGIPRQIAVLCFQFGDGLSNIVWPTAFAPVLCALAGIKLDRWWKWMVPLFILLILTQMILIAIAMFIGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMP6</accession>
    <name>A0A010ZMP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2750635_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="70" mass="8016" checksum="B61E36F29CF4F23E" modified="2014-06-11" version="1">MTLSDRRVLQIIETELAKAVTFIDLEDERIMSEELSDRELIDAVVSRNCWSRALGTLKKVKGAIERLDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMQ8</accession>
    <name>A0A010ZMQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative effector of murein hydrolase LrgA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0664</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441914.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.709"/>
    <dbReference type="HOGENOM" id="CLU_113736_2_0_0"/>
    <dbReference type="OrthoDB" id="1846131at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005538">
        <property type="entry name" value="LrgA/CidA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33931">
        <property type="entry name" value="PTHR33931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03788">
        <property type="entry name" value="LrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="120" mass="13075" checksum="FB9ACC56C91DCE14" modified="2014-06-11" version="1">MKYAKQIFIIFLATMLGELFNFLLPLPVPAGVYGLFILLAALCTGLVKLHDVEDFGSFLLEAMPMMFIPAAVGLIEQFNEIRGILIPLAVIVTVSTVVVMAATGKTAELAMRTKEGRETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMS0</accession>
    <name>A0A010ZMS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Electron transfer flavoprotein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0674</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441927.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.719"/>
    <dbReference type="HOGENOM" id="CLU_034178_1_1_0"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="5">
        <location>
            <begin position="7"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="334" mass="35456" checksum="AD4BFB2014EFFCBC" modified="2014-06-11" version="1">MKKTAEVWTLAEVRGGKIHPVSRELLAWGRELADALGAPLASVVIGSGVKEEAASLARYGADKIYVADAPEFENFKADIEVAALADLIETYKPTILIASATTQGRTVMPMLSARLGCGLTADCTEMAIDPATKRLIQTRPAIGGNVMADIKTKGRDPQMCTVRPKSKRPLASDASRTGEVIEFAPGEELLSSLIKFIKFTPEQAVGLPLQEAEIIVAGGKGMKNAKNFARLEELARLLGGSVGASRMAVDLGWAPYSAQVGLSGKSVTPRLYLAFGISGAVQHIAGMSGAETIIAVNQDPEAPIFRVADLSVQGDAMEVLNALVEAVKKYKERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMV0</accession>
    <name>A0A010ZMV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase, imidazolonepropionase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441952.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.747"/>
    <dbReference type="HOGENOM" id="CLU_023620_2_0_0"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="56"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="422" mass="47752" checksum="2C2DE939DF6F2F59" modified="2014-06-11" version="1">MEQKYTKIKCGKLYDGIKPCFQENMEILIEGRKIKAVGHCLECPEGTETIDLSALTVTPGMIDAHMHTQYFHWKDVYRDTLYNSDGYRTLAVATCAKRCLYSGFTTVRSLGWWSEAYELDVKRAIEEGYVEGARLVVSSHFLCTPGSHGDMTQVVRTNPYLSDYLISQYPTCGNGADFFTGAVRREKKMGADFLKIMATGGFATPNDDPDDIQLNDEEFKAIFDTAKEVKISATAHAYGPRLMKKLINYGITGIEHGSLMDKETASMFENSGTYLVPTFMPYEDAIHPDEESLALKSEEYRRKLRFYQRQLQEGREIIINSKIKLGYGTDMVAVHNNYESGWEYYAWHTNGMDPFRILRAATKTNAEICEIDDKVGTIEPGKLADIAGWGRDLMKDPHALRDCSFVMKEGVAYPAVSRMNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMV5</accession>
    <name>A0A010ZMV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Formate/nitrite transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.753"/>
    <dbReference type="HOGENOM" id="CLU_036896_3_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="270" mass="28303" checksum="339DBAB25A56503A" modified="2014-06-11" version="1">MNYKTPQEIAKSAVAAAISKTGLPLLPMALLGFLAGAYIAMGGYFMIVVTQDAAAFAGVGISKFLGGVAFSLGLFLVVAAGGELFTGNCLMPIGLLSRKITCGGMLRNLAVVYLANFAGALFFALLIFKSGVLTKSCADYALSIAAAKVQIPLFQMIVRGVLCNWFVGLAVWLTFGALDMSGKFIALLMPIAAFVAMGFEHCVANMFFLPLGMMIKSGLTAEGIPSAAQELTASAVAGNLLPVTFGNIIGAAFFLGAIYFVIYRRELTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMZ5</accession>
    <name>A0A010ZMZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441994.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.795"/>
    <dbReference type="HOGENOM" id="CLU_039711_0_0_0"/>
    <dbReference type="OrthoDB" id="1725392at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038728">
        <property type="entry name" value="YkvI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37814">
        <property type="entry name" value="PTHR37814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459125" evidence="2">
        <location>
            <begin position="27"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="409" mass="43678" checksum="E92B8EE9A5FEFEA7" modified="2014-06-11" version="1">MNKDVSVKVPFAVAFSVGSVLFSAHAGGGFATGNQANTYYVSLGWLGPFSAVLAMLLLAITMREAMFMYNSRGLSSYKELFQTLYHPFDGLYVMFEIFFYIMVLMAVAAAISGAASALREYFALNYYLGIALVGALVLALTIFGARLVRMATTYMGIAILATAITIYIIGIVKNGGIGTVLSADFKAGGFSDLPQAILNGFTYAAFQCVTLPTMVACGTPLINKKACDSSMWISFAMNTVALVLSVLMLLSWKSFYTSVDGGSVIPTLTSCREMGIGWLTAMYGMCLLLCLISTGVTTTFGFVARFEKLPLFHGISSSTARSAIVAAFIIALSMGISLAGLTNIIKYGYGYCGYYAIAVVIIPFMTAGIYKNRKFLEVHPEYRGSAARAGSLGIGGRIAPDRAEPGKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN08</accession>
    <name>A0A010ZN08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRISPR-associated autoregulator, Cst2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442004.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.807"/>
    <dbReference type="HOGENOM" id="CLU_068035_0_0_0"/>
    <dbReference type="OrthoDB" id="1098288at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013414">
        <property type="entry name" value="Cas7/Cst2/DevR_sub_I-B/Tneap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010154">
        <property type="entry name" value="CRISPR-assoc_Cas7/Cst2/DevR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01905">
        <property type="entry name" value="DevR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02585">
        <property type="entry name" value="cas_Cst2_DevR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01875">
        <property type="entry name" value="cas_MJ0381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="290" mass="32484" checksum="15C478F3E23EA6F3" modified="2014-06-11" version="1">MEDKCLTITYLTRASYASLNGSDKEADNISSIKKIRMNDGREYPYKSSQAIRRDIREQLAVMGWELSEAAVAKQAKGASSTMGEPEKYIDDDLFGFMIADTNTTKRTGPVRVSPLISLEPYRGDLDFATNYMGVKAGGNPNIFETEIHSGVYRGTILVELDRVGVADAANYDLELKADEKRKRVEALVDAIQNLWGIGRQSRFLADISPKFICAALMKVKNPIYMECLRVKDNCVDEELIKNTEADFKNQISKSVIGERKGFFEKDTTGAKPLGEAFDEIRKWVAETYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN40</accession>
    <name>A0A010ZN40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ethanolamine utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442026.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.832"/>
    <dbReference type="HOGENOM" id="CLU_061142_0_0_0"/>
    <dbReference type="OrthoDB" id="1315713at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034228">
        <property type="term" value="F:ethanolamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007441">
        <property type="entry name" value="EutH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40089">
        <property type="entry name" value="PTHR40089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04346">
        <property type="entry name" value="EutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019466">
        <property type="entry name" value="EutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="407" mass="42876" checksum="F945128933B653A5" modified="2014-06-11" version="1">MFDELISNLSNIQVFTESLHGWVSGLSVNSAIIFVMMLFMLLGAVDKIRGNKWGYGEEFDNGFNAMGPLAIAMAGVVAAAPVLAIILKPIIVPIYGMVGSDASMFATTLLACDMGGYPLAMKLAANESIGNFSGLILGTMMGPTIVFTIPVALSIIKVQDRPYLGAGVLAGLITVPLGCIAGGLLMNMTPYKIDLGTILVNLIPVIIIAGLICIGLWFKPQKMINGFNVFGTAVTILITILTAVAVFEYQTGIHFPLFDKMVVPAEEGGSVPLEDGLLICGQIATVLIGAFPMVKWITRTFGGALETVGRHLGMNEDAAAGMVANLANNIAMFNIFEKMDPKGKLLNVAFTVSAAFVFGDHLGFTAGANPEMIFPVVVGKLVAGITAVILANFLAPMLLAKIKEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNI2</accession>
    <name>A0A010ZNI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 2-aminoethylphosphonate ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442133.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.954"/>
    <dbReference type="HOGENOM" id="CLU_021838_1_2_0"/>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017664">
        <property type="entry name" value="AminoethylPonate_ABC_perm-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03262">
        <property type="entry name" value="PhnU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="64"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="342"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="548" mass="59264" checksum="1C1A1FAC9E276E59" modified="2014-06-11" version="1">MKKIKNANRLESVLLIISLCLLFTAVAAPMAVLFAKAFTDFDGAYIGLANFREYFASPHLVGALWNSLAISAVVSLISLLLAFIYAYALTRAEVPAKGFFKFIALLPLCAPTMMFGIALIYLIGNKGVITMLGLKLPLYGPLGIIVSEVVYTFPQAFLILYITLSYTDNRLYEAARAMGTAPLRILRTVTLPGAKFGLVSAFLVAFTLCFSDFGAPKVVGGNYSVLATDIYKQVIGQQNFGMGSVVGLLLMIPAVVMFVTERLTASDNGVTVSSRSMAYRVIPHRGRDAALTLFCALAAGFIITLFAAVLAASLIKAWPYNMVPTFEHFTVDSPATGGLSSFFNSLVTALLTAFCGTAFVFMNAWLVEKSAANRLLRQAENLFSLIPLALPGLSIGLAFIFFFNMEGNPLNFIYGTAAVLVLANVVHFYSVPYVTASSALKKLDREIEAVAASMAVPSYRTLFKVTMPMCRAAIFETALYFFVNAMVTISAVVFLYPPDFKLASVAIVNMEDAGDIAPAAALSVLVIFVNVAAKLLYEYTFVMKRSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNJ3</accession>
    <name>A0A010ZNJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrothymine dehydrogenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Dihydrouracil dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0922</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydropyrimidine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042042_4_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044512">
        <property type="entry name" value="DPYD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073">
        <property type="entry name" value="PTHR43073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="337"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="370"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="408" mass="44260" checksum="612B4D67E9C87840" modified="2014-06-11" version="1">MNMKPNMQVEYCGVNFKNPLIVASATPTKNAEYMRKCCEAGAGGLISKTISPEPLAQQYSNPRFTILHKSGWPNIYSNYSAEFLCTYNTEEWWPQMVEAKKVCDEYNTTLVGSISGVSIPNWQELAKKMEDIGVPMIELNFGCPHPKDLGYKSGQVLGNSPDAAAEVVNAVVNAVKIPVFTKLTGEAVNIVESAGKVKAAGASGVTVINRYSSLDIDIKTGRPILHSAYAGVGGPWMRPIMLKWVAKIAKEHNIPISATNGIYTWEDFAKAMMVGATTVQVCTAIIYGGKKFGVIKDILDGFENYLIENNISAAKDIIGKTLPQIVTWDKVNRDIRPCSSVDPEKCNGCGLCPNWCFKDAITMTGEGEDAKAVIDSNKCEGCGLCPSLCPEDAVSIKADTPIFLGDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7B7</accession>
    <name>A0A011A7B7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type cobalt transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441227.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1713578at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="281" mass="29985" checksum="586AFCC92998C548" modified="2014-06-11" version="1">MISVENLSFIYDGSERRALNEISLRIPRGAFVGVTGASRSGKSTLLRAMAGIVPHYLRGRFFGAVKVGGLDTLDTAPQQIAHIVGFVGEDIESQMICETVEEELLFGLENFAVPREEIEPRLAAALEMLSISPLRGRKISSLSGGQRQKTALAAMLALSPQVLILDNPSAELDPAATESLYDALAALNSRGMTVIAAEQKVGTLCRFATQMIVMDDGGALLCGAAQQVMNDTAALAAAGVMRPRRIELGARLRAEGLYDGDMPLDIPRAAAMVRGICNDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7N8</accession>
    <name>A0A011A7N8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cation/cationic drug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709287.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131462_4_2_0"/>
    <dbReference type="OrthoDB" id="1963715at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="124" mass="13166" checksum="80DBDFC767785627" modified="2014-06-11" version="1">MLDKITLFLILASAGTNALGSTVMKHAYGGDSDMVSSGVVGAFLKIALNPWIVIGLGLFGISFFFMAAALSRAELTLAYPLMSGIVYLLLLAIGFFIFHEKITLMRIGGMAFILAGITMLAIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7V8</accession>
    <name>A0A011A7V8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709395.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_1_1_0"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="200"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="398" mass="43682" checksum="16035A28BB0B7C5D" modified="2014-06-11" version="1">MKEHLELSSLGASLLAEAERISGEIQDWRRDFHQFPEFAFEENITASKITNVMRSIPGMAVTTGFAIQTSVIGVLGAEIPGPALMLRATMDATAAEEQTGLPFSSCMPGAMHGCGHDAEMASLLGAASVLSKYRGELKQRVVFLFQPAGEGRSGAKTLTENNIIEKFHIGRSVAVNWASELPYGELFTRRGVMTALSDRIHIDIRGTAGHAAEPHMTVDPVTIAANVIIMIQTMLSREVDPREPVVVSFGQVESGEAYNIIPEQANLWGTLRAFDPKVRDFVQSRIEAVAPAIAKAFRGLASVEYTRNYAQVDNNLDMVDELLRVGVPFFGEDGLNMLERPLLSGDDFAFFSHRVPSLFMLMGTGLEYPLHHPRYDVPESMLSFSAAWEAYLALTFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7Y2</accession>
    <name>A0A011A7Y2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisA</name>
        <name evidence="10" type="ORF">Cloev_0257</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.278"/>
    <dbReference type="HOGENOM" id="CLU_048577_1_2_0"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="236" mass="24664" checksum="891C5567B5F56AE9" modified="2014-06-11" version="1">MKIFPAVDLYEGKVVRLTQGDYSRRRVYELSPLDAAKSFRDAGCPRIHVVDLEGARTGEPKHLKELSAIASLGLFVQYGGGLRSAEAVARAVSAGAGRVMAGSLIFKDLGRASELSARFGDKIMAAVDIKNGKVVHSGWLAATEFSAAEAVDKLFAMGFSSFLVTQTERDGMMSGTDASVYGSLAARGRFIAAAGGVTDLHDIRALAAAGVDAAVVGKSLYEGGITLAEALDACSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7Y7</accession>
    <name>A0A011A7Y7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter, outer membrane factor lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441433.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_13_0_0"/>
    <dbReference type="OrthoDB" id="1619477at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001431318" evidence="2">
        <location>
            <begin position="24"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="499" mass="53525" checksum="122323CE2B0731C6" modified="2014-06-11" version="1">MNFLSKCTAAVMLMAAAAGAAMAAPGAKNELPSADIRLKEVSWTELAGAYPIPAVSPDISPALTPERLASWWDAFGDPQMTALVKRSLENNRTLATARARVTEARASLGVSRAALLPWLGSTDFWNNGRTPVEAGGSGNGGSLYKLGLDASWEIDVFGGQRAKVEAQRATLEAQYAALYSAWTSLASEVAMNYISLRTLQERLAIARYNLSLQQNTVDIQQSKVDSGLSDSLALKQAQYTMEQTKAGIPSIESSIEQTMNALAILVGEVPGTLAEKLAAKQPIPKISDTRFLGIPANAIRQRPDIRQAERLLVAQLARKKSAQADLWPKFYLTGSIGTEAGNWGSLFGGPAKLYSFMPQISWPIFHAGAIRSNIKAQGAIAEQLLASYEQTVLSAVGEVRDSLSSNVKEYERSESLKRGVEAAQAALDVANDKYANGLVDFTNVINAQRSLTSLSEEYVISQGQISANAVALFKALGGGWQPMEEAERALAEAAKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A813</accession>
    <name>A0A011A813_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708937.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.309"/>
    <dbReference type="HOGENOM" id="CLU_068890_0_0_0"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12682">
        <property type="entry name" value="Flavodoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459351" description="Flavodoxin-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="33"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="189" mass="20364" checksum="2D6F880D9EE7E367" modified="2014-06-11" version="1">MKALVMTILAMAALFGWAVHGEAAPALAGKKPLIVYFSWGGNTRVVANQIKELTGGDLFEAQTVKSYPKEYRATTEQAKNELNSNARPALKVSKLPNLGSYDTVIICHPNWWGTMPTAMMTLLEANDLSGKKIAQVVTHEGSGVGRSGGDLKKLCPKSEILSPTAIRGGGVKNAQRDVENWLKETGILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A820</accession>
    <name>A0A011A820_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2492345_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="86" mass="9275" checksum="1C201C21F932F543" modified="2014-06-11" version="1">MKRTLTIIILLCAAIFAGILIWDVYCAEAAGARPEYPASAPGEKTAAGRTKYTRTMAYLKIYDTLTAVRRAAAGRFEGGPAVFSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8M6</accession>
    <name>A0A011A8M6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441723.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1591664_0_0_0"/>
    <dbReference type="OrthoDB" id="2215168at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="17890" checksum="DBD756F0AA1A603A" modified="2014-06-11" version="1">MLVNEFIKRVSVRLGDEARITYSSKELISCLNDAISQLSLERIAAHDPLMIREVTVTPGRTTVPAGFVRFVGQEPFYIDGAKFASLDGSTEKRTARCYMAKAHVESAGDDLPFDDATSLGALMDYVVVLAGARVGYASQVESTLADRMSGAYTGRSASDAGAVAKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8Q4</accession>
    <name>A0A011A8Q4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709622.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137433_1_0_0"/>
    <dbReference type="OrthoDB" id="1801639at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="155" mass="16852" checksum="8A8A62B6E305A948" modified="2014-06-11" version="1">MSSATKIKGRQTMICIIMTALLVLLGCALFYYGKDHDIILDNKSVVIDGVCYEAIPYLTAAIDGNSETELEFYPDDRDMAKVSGPRHTIKIAVVNEETEEIVKTVERTLSLGISPSVMLSLPAVVAEASDVMLPLPKTNAPQDDGNSEENAEESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A901</accession>
    <name>A0A011A901_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441870.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.667"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="423" mass="44351" checksum="94F9DE93BB769009" modified="2014-06-11" version="1">MEIVVLFGSMTILLALSLPIGISLGMATAITLVYTKSVPLIMIAQNAFAALDSFPLLAIPFFMLAGALMSYGGISKRLVSLAEAMVGAVIGGLAMVTVTACMFFAAISGSGPATVSAIGSFMIPAMKAKMYDDDFAAALTAAAGSIGVIIPPSIPFVIYGVVSGASVGELFMAGILPGIIIGFSLMAVSYRTAKKRNYPVSQNRVPIGKAFREAVWALLVPLIILGGIYGGIFTPTEAAVVASVYALIIGKFIYKELDFRTTYDAFKDAVLVNGATTFMIGLSMSFAAFLAMEQVPAKIGAWMLSLSSSPAMILLIINILLLIVGCFVDNISSMIILTPILLPIVTKIGVDPVHFGLVMTVALATGFVTPPYGANLFVASAVSGVSMVRLSKAIIPMIAVMVLCLLLFTYFPSISMCLVRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A946</accession>
    <name>A0A011A946_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441926.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_9_2_0"/>
    <dbReference type="OrthoDB" id="1188552at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="44"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="475" mass="51448" checksum="45B74081975C0D21" modified="2014-06-11" version="1">MERYGKITEEIYKELLSVTGPGGVIMNDAEVLDNYAWDQAGRIWGHMPEAVVKPADTAQVSAVMKIASREHIPVTPRGAGSGLNGGAVPLAGGVVLSLERMNRILEIDKVNRVAVVEPGVVTNDLCRAAAEEGFLYAGYPMSTETSFIGGNFATNAGGGKVIRYGNTRRHILGAEIVLPSGEIINLGGRFRKDTWGYSLLNLLAGSEGTLAVVTRLIVNLEPKPGRTVNLLACYPTVEELVESVAKVIGSGKRIISCEFMDKNLVKYTTEYLGCTLPEQKRSEGYLLIQVEGDTEAQLEDGYETVGKICLGCGALEVFVAESRTDSAAMWNVRQNGLEGMRARDPHACASGDLMVPLSAVPKMIRRIREISAEWRIEIGIISHIGDGNIHPIPLKPAEMPPERWAQHAEDFFAVLIREAIALGGVGSGEHGVGHVKQKVLMENKSPAELEVMQGIKRAFDPYNIMNPGKMFSPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A997</accession>
    <name>A0A011A997_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNF family Na+-dependent transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441969.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.779"/>
    <dbReference type="HOGENOM" id="CLU_006855_3_4_0"/>
    <dbReference type="OrthoDB" id="376209at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="469" mass="49919" checksum="AE67B0339D9D15B3" modified="2014-06-11" version="1">MSTGSKRDGFSSTLAALMVALGSAVGLGNIWKFPYMTGTGGGGAFLVIYLFFVFCVAVPIMISEFVIGRRSRMNAVGAFRKLTGNPRTPWSGIGFLGAVSSYLIMFFYSCVAGWVYCYTFKAATGVFADITKEGAGAMFASTIGVGGADASFFSSTVLAPIFWQILVLVVVGTIISLGVARGIERAIKFMMPALFVLLIICVVRALTLPGAGDGLRFLFHVDFKQVTPGVILAAMGLAFFKLSLGMGTMITYGSYFTDDADLSVAPLKIAIADICISMLAGLAIFPTVFSFGVEPGAGPGLLFITIPLVFSQMPFGQVLLFAFFLLTAFAANGAMLSLVEVPTIWMSEEFNISRKKSALINCVIIGAVGILAAGSADGSGYFGGITIFGRGFFDLFDYLSSNVTMPVGGLCIAVFTGYVMKRGDLFDELSNHGMLRNECRAGFIRVLLRYVTPVLVMVIFLNALGIIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9C2</accession>
    <name>A0A011A9C2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442003.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_488097_0_0_0"/>
    <dbReference type="OrthoDB" id="1028553at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="598" mass="68762" checksum="DCC42EA2E2FF7164" modified="2014-06-11" version="1">MEVKDIDYLFKLRNHWWFDAGIAAFYDIAGRLKKSDRQKWSEVKVIVRPDGIVVSAPDRLLKPFVDACYEYLGAQWWNVSSSKQEEAKDLVVYNKSKKTFLCVPRRNPTPVAALSVGGSSWKADYDIYDDLPDEMKKKTDEFLKESGKSLWGIKKDKLPYEQPVCHPHIETFPVKGKKRVCSVCGQELVCEGVNQTVFPLFSSQSAAFSFNSKFGTPDIVCWECAMLGKFAVHSALYKVADPYTQIMQIYSNNMEALINAHDVMGNSSDIRIFERDKLYFRDFGTSESLVELARLPYEVLWSFFLVSFDELDKRKKNAIDAEDKLKRVGSLSEEDLDCLAATGVVTMSLEKKGQTFITKELVDFHDSVYIFRLIDYVEREIREDKIINKDKGDFWKNLFWDLLLVQNKQKKFDPVNGLYRNRMLQKVFEKSSILRDAENFVFKKSLIENYPYLYRILFFVTLYERVINKRDGEHEGGKGMTKEQVAIATSLGAQIIIGGKKALMEDSKDVNKLKPLKGDLFSLRKTRSATDFLEQLGRLQFRYGLVLNQEIIKGILVEKDVKFEDFKAYCMISALNGYNREFGFAEKSNSASGAAENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9D1</accession>
    <name>A0A011A9D1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cas1</name>
        <name evidence="10" type="ORF">Cloev_0759</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442009.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.811"/>
    <dbReference type="HOGENOM" id="CLU_052779_2_0_0"/>
    <dbReference type="OrthoDB" id="1581397at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09722">
        <property type="entry name" value="Cas1_I-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019858">
        <property type="entry name" value="CRISPR-assoc_Cas1_HMARI/TNEAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43219">
        <property type="entry name" value="PTHR43219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03641">
        <property type="entry name" value="cas1_HMARI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="333" mass="39142" checksum="2C53807A971B49F7" modified="2014-06-11" version="1">MGKTLYLLSNGELKRKDNTLFIARENENPKFLPVETLDEINIFGEVDFNKSLLEFISQKEVILHFYNHYGYYVGTFYPREHLNSGAVILAQAAYYMDAAKRIEIASSFVIGAIDNMKRVMEYYQRRAMVEISDIVEALDVYSERAPQSKDVAELMGIEGNSREKYYEFFDRVVKDDAFKMVNRTRRPPSNRMNALISFLNTMCYTLVLSQIYRTHLDPRIGFLHETNFRRFSLNLDVAEIFKPILVDRLIFSLINKREIQEKHFEKQSGGGIYLSESGREIVLRAWEGRLNETIEHPALGRKVSYRGLVRMEIYKLQKHMMENIKYVPYTSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9G0</accession>
    <name>A0A011A9G0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphoglycerol transferase family protein, alkaline phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484870.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.841"/>
    <dbReference type="HOGENOM" id="CLU_021310_0_0_0"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012160">
        <property type="entry name" value="LtaS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005091">
        <property type="entry name" value="Mmb_sulf_HI1246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="262"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="638" mass="71698" checksum="FBC92189E5D794C8" modified="2014-06-11" version="1">MFFPHKDKPVSISGYLFAAVVAAAVWLKFLSVDYAVADVLNWPTFGVLTMHALRHTARALAVSPSSLGAILCLLLPLMFFPPRRRAAALVVMDLLLSALVLTDRLFIRYYADIFIFHDLMLVPQTGLIAKSIWALLKPWDLLIFADIPLIVWLMRGGRLRVVFKRERRRDAALLLALFLCAAAVQGAAVWHIIKFRPNIIDAMYDRLSVCAWVGTATFHWWDFFSLTRKALKPQNVSPETVDEIRGWFAAHRTVPHGGTSAKNLILVQCEALQYFAVDLEIGGVPVTPNLNRFKNECLYFPNTWSQAAGGNSSDAEFMANTGLFPAAFGAAYTLYADNDYNSLARAMRRRGARAVVVQGTRSAFWNCHRMHPKLWFHRQYSQNTFPNDEAIGLGLSDEAIFSRALQIFREMKGPFYGFIVTLSSHHPFDFAELPRDTLPLPPELRGTLIGSYLLSINYFDRQFGMFIDGLRSSGLLDKSLVVVYGDHPAIPIAYKEDMEKLLGRKIEEAVDWKATRRIPLLFRTPETAKAPRVDERNVGQMDILPTVSGLMRLDIGTAFGNDLLGKDAVGPVIFRNGSYIEGNVYVEPAAGRATDLNTGERLDCSAYDGLTDEAERRLRYNDLILEKNLIEKIIGKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA08</accession>
    <name>A0A011AA08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ORF">Cloev_0991</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711002.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1061"/>
    <dbReference type="HOGENOM" id="CLU_061015_2_1_0"/>
    <dbReference type="OrthoDB" id="1456375at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="85"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="180" mass="20677" checksum="BA63C4F1A73B029C" modified="2014-06-11" version="1">MTPRLLTKYTDEVLPRLNEQFQYKNVMEIPRLVKVVINIGVNEAKLDQKYMDASLNELTIISGQKPMMKRAKKSIAGFKVREGMPVACAVTLRSERMWEFVDRLFSIALPRIKDFQGISKKGFDGRGNFNLGLKEQLLFPEIDYDKVIRQRGMNITFVTTAKTDEEAQALLKELGMPFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA17</accession>
    <name>A0A011AA17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ORF">Cloev_1001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711018.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1070"/>
    <dbReference type="HOGENOM" id="CLU_015857_0_1_0"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="12"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="256" mass="27305" checksum="3ADADDFCB564215D" modified="2014-06-11" version="1">MITFKSDRDIAKMRRAGQIVADILKLMREMVKPGIDTLTLDEAAEDLVKKAGAKPAFKGYKVPWVSVPFPGTICASINNEVVHGIPSSDRVLEEGDIISIDTGASIEGFFGDAACTFAVGKIGEERQRLLDLTLESLHKGAAAVKPGATLGDIGFAVENVVIPAGCGLVRDYAGHGIGHRLHEAPQVPNFGKPGSGITVKPRMTFCVEPMVMTGAEEVKTLSDGWTVVTNDGSDAAHFEYSLLVTDDGVEILTPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAB9</accession>
    <name>A0A011AAB9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="5" type="ORF">Cloev_1124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442436.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1197"/>
    <dbReference type="HOGENOM" id="CLU_039379_1_1_0"/>
    <dbReference type="OrthoDB" id="631784at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="337" mass="36199" checksum="A85F5F7FF781782D" modified="2014-06-11" version="1">MLIALDAMGGDHAPEEPCKGAILACREKPHLSIALVGDSEKIKPLVEKAERNVRSRLSIVHTDEVINGSDSPSLSIRRKKNSSLVVGFEMVRSKEADGIVSSGNTGAIAAGAVLLLGRIPGIDRPGLGAVLPVLNRSTLLMDVGGTVRCKPINLLQFAQMGSIYMKLFQNVENPSVRLLSNGEEMTKGDDVISAARGLIEASCLNFQGYAEGKDIPNGISDVVICDGFTGNVIIKFGEGLGELLKSQFKEEYIHHTLPKIGLFFMWPAMKRVMGRFDWEKYGGSPVLGVNGSVVKVHGRSKANAIAHAITGAANFIERNGVDRIREEIARGVQNGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCH1</accession>
    <name>A0A010YCH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2057306_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="119" mass="12615" checksum="BC90FF75DD13431E" modified="2014-06-11" version="1">MTFMIDLVSLWRDAKADTPVCTVTGTTKNMILNAMMDGAHSYEAMAKATPLCADNECAERNPSGRGCRENVEALISIYLPVYEMMTEGGGCRHSKPQPKPDGCSGTRTDACGGCTGCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCP2</accession>
    <name>A0A010YCP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441304.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.124"/>
    <dbReference type="HOGENOM" id="CLU_000445_89_5_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038318">
        <property type="entry name" value="KdpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025201">
        <property type="entry name" value="KdpD_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13493">
        <property type="entry name" value="DUF4118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="292"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="519" mass="57383" checksum="DCF9C4B88BC8DC0B" modified="2014-06-11" version="1">MERIFSRLKRRLFMKRPARFAVLAASLIVGATLIGLLFRALGFPETNIVIIYLLAVLLTARFTAGYRWGIAVSFVSTFTYNFFFTVPLYSFAVNDSSYIVTFAIMTITASITSAVTSRAKASEEESLRREAEVLMLYSFTNRLSNAFTPHEIAGVAVNTIHGFWGWQAACLCFDGDGRPENSYIQQVGEDTPVWRMTEDPERIGGEMLRLRSACLAGAEFFDWPVYSTDKLLAVIRIPAPDAIAMTGDQRQALHSVIKGAALAMDRYRSARARLRSEEEAARERYRGNLLRAISHDLRTPLAGIMGTAEILIGRDRDGGAEKSLALAIYNDAQWLHDIVENVLSLTRIQSGASVIKYEPSALEEIVEVAINHVKRRLAGRRLEVRLPDELLMVRADSRLIQQVLVNLLDNAVKHTPPGKTIEISAARENGGFARVAVADEGEGIPLEDLPHIFEMFYTSQKRSADVKKGIGLGLPICEAIIRSHGGTASAENITDGGARFTFTLPLAKDGQNEETHTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCQ7</accession>
    <name>A0A010YCQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar diacid utilization regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441318.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_3_0_0"/>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012914">
        <property type="entry name" value="PucR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07905">
        <property type="entry name" value="PucR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PucR" evidence="1">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="466"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="530" mass="60884" checksum="5A66BCB143AE96D9" modified="2014-06-11" version="1">MRESIDVEWLTEITMFKNNIRLVAGGGGLSRHVTYVAVQEAPDFYEWIEGGEFILSTWYAFKDDIDAGLAAIRNMCDKASGICIKVNRFIDKIPPEYLRCADEFNLPLFVVDKDVKFREIIKSITLEINMAHVNVLIQLNDYYTYLFQTALENGSADSMLLDFARRSGLIAITISTDFKQLRGMRSFQKLPNHEYRLQVIKDIINSNSNRVKYFCENEYHIFPCIARGYCYGYLVVLSVNVLSERQRLYVAQLVNIITIKWLDRQEQENDSLLSLLDMIMNSPGKDQEHIVQFLTKKSIDISSGIRAVQLKYSKSKKGNAKVNFSVVQRFLVDLMAVKPNLLYIWDKAADAFTLLIDGQGCEKEGEGLSHGFLYNVVKISENYKEISVSIGPVVTKVSDISISIKMAINSFLFKNSEIPKVMYYKENLMQFALLGGAGSRESDFFLEEVIMPLAEHDRRYNDCIMQTLSSVAENVSLEQAAQKQNVHVNSVRYRLQKIKNICGLDFFSQAEKYVIITAYMIYQNRDKYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD25</accession>
    <name>A0A010YD25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Altronate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UxaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441406.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.251"/>
    <dbReference type="HOGENOM" id="CLU_029189_1_0_0"/>
    <dbReference type="OrthoDB" id="889365at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007392">
        <property type="entry name" value="Gal/Altron_deHydtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04295">
        <property type="entry name" value="GD_AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GD_AH_C" evidence="3">
        <location>
            <begin position="2"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="387" mass="40652" checksum="634A73DC87418677" modified="2014-06-11" version="1">MKFLGYRRPGGRTGVRNLVAVMPGVLCSSAAARKIADAVPGTTFLYNHNGCGQSPSDTEHTLEILSGLIANGNVYGALIVGLGCEATQRELYLAAVSAKSDKPLHYISIHEEGGIGGAVAAGIKIAEKLVEEARKLKREEIDISELIVGLECGGSDPTSGISANVVLGDLSDRLVDLGAAVVISETSEAIGAENILLARGRTPEIGRRLCEMTARWDRDIKEQTGADIRLTNPTPGNIAAGLTTLSEKSLGCIHKSGTRPFEGVLAAGEYIKGRGLYYMDTTAYDCGSITAKIAGGAQLVAFTTGMGNPIGSPVAPVIKITGNHATFEKHNDMIDFDTSASLSGEKSVEELGEELLDFTLSVCCGRETKAEINEAGVVFVNQRHSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD43</accession>
    <name>A0A010YD43_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="7">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tyrS</name>
        <name evidence="9" type="ORF">Cloev_0246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441423.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.266"/>
    <dbReference type="HOGENOM" id="CLU_024003_0_3_0"/>
    <dbReference type="OrthoDB" id="402899at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="234"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="425" mass="47778" checksum="F88E01B4724CBB6E" modified="2014-06-11" version="1">MYTNALKVLRERGFVEWSSHNEELEEHFMKNMVTGYIGFDPSADSLHVGNLVAIMGLAWLQRLGHRPIAIAGGGTGRIGDPSGKSAERNLLSEEQILHNVSCIAEQLKHFLDFESGDNSALLVNNNDWLKNENYIEFLRDTGKYFSVSFLVNREYVRSRVLDPDKSITYTELSYILLQAFDYNHLYNEYGCTLQMGGNDQQVNIIAGMDLARKKSGGQCYGITFPLLLNAQGQKFGKSESGAVYLSSKRTSIYKFYQFWINVDDKDLEKLYRLFTFRELDEIEALLEEHNKAPHLRKAQKELAWEMTCRVHGEEAAKRVLDASAVLFGETEIKKAQADVLETLAAEIPCAEADLAEANGVTDLLVLCGACDSKGNAKKKIKEGGAYLNGEKIADAGRQITEEDLLAGRYLQLNVGKKDFRLLKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD63</accession>
    <name>A0A010YD63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708909.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.284"/>
    <dbReference type="HOGENOM" id="CLU_111585_5_0_0"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="110" mass="12433" checksum="47D62261AA0D882F" modified="2014-06-11" version="1">MPKKELPPCPVETTLTLIGDKWKVLILRDLMPGTKRFGELKKSIGTVTQKVLTQQLRAMEESGLLTRKVYAEVPPRVEYTLTGTGRSLKPILDAMVSWGESYKETLERQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD95</accession>
    <name>A0A010YD95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441464.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080392_0_0_0"/>
    <dbReference type="OrthoDB" id="1933353at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458076" evidence="1">
        <location>
            <begin position="29"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="282" mass="29995" checksum="57DF8AAD54FEA910" modified="2014-06-11" version="1">MKKTTMFFIVLLAAVFVPCISAPVPALADTPVTIREPFIRDLQLPVGMLYDGEGSLYIAEWAAGRVCKYDSKGRRTLVTEEVAHPSGLAMDEDGRLFIASYNEGIIYMFEEGRLRRFVSGFNVPAGILWHDGILYVANRDAGEIVRVSPVGRKDVLSKGHHSPVGIARFDDGSLVISCLGGLIQRLWPDGRVTTVSDALKSPAPGIVRDGAGAVIAADYGGTRIARITLDGVAETVADGFSTPVGLVRRPDGGLVVAAWGDAAAFKVEPGISGPSDSAENKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDL5</accession>
    <name>A0A010YDL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic acid-binding protein, contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441559.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124456_3_1_0"/>
    <dbReference type="OrthoDB" id="2034229at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="139" mass="15058" checksum="DBB81E7AB7CFB7E0" modified="2014-06-11" version="1">MKISFDTNVILDAIIEGREGGAEAKQLILAVAQDRAEGLISANSITDIYYIARKYLGDVKTREVIYSLLTIFSVAGVGEDDCLNALELPMGDFEDALLAVCSQRDGAEYIVTRDEGFIAAPGCPVKAVRPAMMLSILQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDP2</accession>
    <name>A0A010YDP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3166437_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="47" mass="5376" checksum="66E9F2DDB95FE716" modified="2014-06-11" version="1">MWYINMALWLGTIFGFFGWALFRIHKAEKRKKAGAAKKIAAEPAAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDP6</accession>
    <name>A0A010YDP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709112.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080179_2_0_0"/>
    <dbReference type="OrthoDB" id="1474443at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039446">
        <property type="entry name" value="DauR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039445">
        <property type="entry name" value="DauR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013559">
        <property type="entry name" value="YheO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35568">
        <property type="entry name" value="PTHR35568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13309">
        <property type="entry name" value="HTH_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08348">
        <property type="entry name" value="PAS_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS_6" evidence="1">
        <location>
            <begin position="14"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_22" evidence="2">
        <location>
            <begin position="173"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="240" mass="27352" checksum="E989F3F90099923F" modified="2014-06-11" version="1">MIIVTASQKMNPRLKILIPVVRGLAKILGKDYEVNLHDVSMPEHSLVLCENGYVTGRREGGPMTDFGLFMLQSEEYQSKDGIYNYLAKNNRGELIKCSCIFIRDENEKIIAFLCINYDLKKAVAAQELIESLVKVDMGKIEQYPESFDPPSEPHGKFPEPVRESFAQDLEEVMDDSLAQAKRRIGKPLQYLTKPEKKQVIKELHDKGFFLLKGAVDTLAAEMGNTKFTIYAYIRDIQKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDQ7</accession>
    <name>A0A010YDQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441635.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.470"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_0"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="256" mass="27602" checksum="48ACF61DBD20E7AC" modified="2014-06-11" version="1">MAKNFTDLTGKKAIVTGGAQGLSYGAAEGLMEAGAEVCIMDINPKVADVAKAFCERGFKCSAVTANLGDKKERREKFLEAVEKLGGHLDILVNGAGVQRRHKCEEFPEEDWEFVLNVNLNAVFALSQMAGQTFIRQGSGGKIINFASMLAFFGGYTVPAYAASKGGIAQLTKALCNEWAEKNINVNAIAPGYMDTEMNTALTDPNNPRFKEITDRIPHKRWGTPEDVKGPIIFLASSASDYLDGAIIPVDGGYLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDU1</accession>
    <name>A0A010YDU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441721.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1522615_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="176" mass="18820" checksum="AD7A7D6FC1BC9A26" modified="2014-06-11" version="1">MKAQKILAQVRLYVGDAAKAKFADWQAVRAINDALRVMAEENAKSAGLLFRRNADVVLEEESGVLPSDYLNVIRGFGAEGRELLQVHGDSPGAGEYAIRGDVLCSGEPQVTLWYFSTPPAVTDGESEIEVPERYATAIARAAAALLAGGEGGAVSVVNYFLPNMRPAAPQRKEAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDZ6</accession>
    <name>A0A010YDZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type multidrug transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441795.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.583"/>
    <dbReference type="HOGENOM" id="CLU_039483_8_0_0"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="377" mass="42453" checksum="60951D05AD2D5F77" modified="2014-06-11" version="1">MNWERMHALIVKEFIQLMRDRITLAIVVFMPLAQLLIFGFAINTDIKHLPTVIFDQSRTQESRSMINSLTSSNYFDVARYAGSVKEVDETVESGRAKVGIVFPPDYASRIKGGRQTSVQVIIDATDNLSASSALAAAQTIGMLKSQEILAEKFSRLGVKVPGQTIDMRIRLWYNPDFITSWYIVPGIMGMLLTITLISMMSMAIVRESEQGTLEQLLVTPMKIWELLFSKIIPYIVVGYVQVFISIIVGIFVFNMPFLGSITLFYFLTFFYVVASLSLGIMISCFAQNQTQALQMSVFIILPSVLLSGFVFPLESMPLGFRYLGECLPITYYISLSRQIILKGGGLAYVWRDTLALIAYIAVMFTASILMFKRRFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YED3</accession>
    <name>A0A010YED3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710554.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.750"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="314"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="8"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="426" mass="45244" checksum="26FE8638222CA414" modified="2014-06-11" version="1">MEAVIVFSILIVTIALSIPIGITLGLATGLAMWLTSDIPMLMLAQKSVTGLDSFPLLAIPFFILAGALMCNGGISRRLVNLAESLVGFITGGLAMVTVLACMFFAAISGSGPATVSAIGSFMIPSMKERKYDAGFAAAITAAAGTIGVIIPPSIPFVIYCVVAQCSIGDMFIAGIIPGLIIGFALMIVCYGTAKKRHYVSLAERPKLSVVGKAFIDAIWALMVPVIILGGIYGGIFTPTEAAVVAVVYSILIGKFVYKELDGKSLYECLRVSGLINGATEFMIGLSMAFASYLTMAQIPMHVAEWLTNFSHNPFMLLMIINIFLLIIGCFVDNIAAVIILTPILLPVVKTIGIDPIHFGLIITVNLACGFISPPYGINLFVASAISGESIENISKSILPSFLAMVACLLLFTYFPIFSLGLLQWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEL6</accession>
    <name>A0A010YEL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative NADH:ubiquinone oxidoreductase, subunit RnfC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0778</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710680.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.830"/>
    <dbReference type="HOGENOM" id="CLU_010808_0_0_0"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010208">
        <property type="entry name" value="Ion_transpt_RnfC/RsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017054">
        <property type="entry name" value="PduS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026902">
        <property type="entry name" value="RnfC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43034">
        <property type="entry name" value="PTHR43034"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13375">
        <property type="entry name" value="RnfC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036408">
        <property type="entry name" value="PduS_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="245"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="448" mass="48946" checksum="9AF7B72BEFEBC9F2" modified="2014-06-11" version="1">MELLEAIKWAGVVGEGGAGFPTYAKLDTRAECFIVNGAECEPLIETDKYLMRTFPDEIVAGTAAVSAHLGAKRTVIALKSKYKAESEALSRAIEKSGAAIEIVKMPAFYPAGDEHTMVYYVTGRSIPARGIPISVGCVVDNVGTMRSVYEALEGRPVTDKYLSVTGDVREPVMLRVPIGTYFRECVALAGTGLSEYAAVNGGPMMGLVLSEKEKIDAAVVTKTTGNILVLPPDHYLVERSKLKMQRIRLQSRSACIQCRYCTDLCPRWLIGQEMEPHLVMRGLWMESRIKDDAEFVRAFGDAMNCCSCGICELYACPMNLSPRRVNEYFKGVLRSRGLESKVEPHPAARGSFGDRLIPTERLVARLGLRDYYPGHAGRCIEYRPKEVFIPFRQSIGRAAEAVAENGARVRRGDLIAKAAEGLSSNIYASIDGTVTDIGVQGARIVSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YET3</accession>
    <name>A0A010YET3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710800.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129727_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021219">
        <property type="entry name" value="DUF2703"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10865">
        <property type="entry name" value="DUF2703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="177" mass="19445" checksum="9189F81373CB5F20" modified="2014-06-11" version="1">MKTITLAHYTMKDIDPAPWTETWDNLVKFGSRMAPKLIPLGFKLKLRKVIMDELTQDNLMTANMVTIECEEAGTPETPIENLLMLELDFTPCAECKTPGGQEFPCRTFTSFGGDVCQALPEEFFMEATLRVAFKSQHECGCHCGDCDSCASGCGDEEAGVRTDDCGGGHHHDNGGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEW2</accession>
    <name>A0A010YEW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Na+/H+ antiporter NhaD-like permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0870</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CitM (TC 2.A.11) transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710845.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011920_4_0_0"/>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000802">
        <property type="entry name" value="Arsenical_pump_ArsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00758">
        <property type="entry name" value="ARSENICPUMP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="10">
        <location>
            <begin position="17"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="428" mass="45102" checksum="64021D4A38E77820" modified="2014-06-11" version="1">MTIQAWAALAIFLGVIILAASGRMKTATASLFGASVMVASGLLSSEDAVKAIDHNTVGLLVGMMIVVGILSKSGLFQYLAVKAIKVTGGRPILIFWILSLLTAVLSAFLDNVTTVLLVTPVVLSLCELISMNPLPLLLMELFASNIGGTATLIGDPPNMIIASVAGFSFNDFIVILAPVAAVILCATTAYVAFYYKSELKSDPDAAERLSEVDESKLIVNRPLMIKSVVIIVLVLIGFTTHRIFHLDASVVALTAAGALLAISLLDEGTILHNDVEWPTIIYFLSLFIMAGGLKANGVLEEASKLLTLLFAGNPLLMLMATLWISGLVCAFINNIAFTAIFVHIIGSMGQAAGVAPEPLYWALALGACLGGNGTYFGAAANAVVADFAAREGIEIPFAAFSRIGLRIVFISLLISSAALLWIGRGLWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF27</accession>
    <name>A0A010YF27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage head-tail joining protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442206.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2877876_0_0_0"/>
    <dbReference type="OrthoDB" id="1972830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008767">
        <property type="entry name" value="Phage_SPP1_head-tail_adaptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038666">
        <property type="entry name" value="SSP1_head-tail_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05521">
        <property type="entry name" value="Phage_H_T_join"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="63" mass="7092" checksum="932DE73944CE3BBC" modified="2014-06-11" version="1">MKLKDKKIEILAVTMIKDPEGFPTQVLAPIAPPLWAYFRQLSGKEVYAAMSVQAVEEVQFVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF44</accession>
    <name>A0A010YF44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative domain HDIG-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442262.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056349_2_0_0"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="179"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="337" mass="37485" checksum="BC51A6C52C7C5672" modified="2014-06-11" version="1">MTANLLLNSQEVRKLPAGSLFKAIFVVSALSQKSDKNGKPYYDVTVSDSFGSIEAKVWSDAQWLDKSEAEPQNDDDRLPVDKILLLVGKTVGINGKAAEYRGQLQFNFNKLTLLNQDKYPPAGYLPRSPIPLDELTARFEALVRDCGGEAGDFLRKVFTGELWSRFRDWPAAVSHHHAYANGLLEHTLSVAECAKSMAGSMLGAGYDVDVDIVVAGALLHDIGKLDSYRMISVPEMTVEGALLDHVAQGYMRFNELAAQFGLTDKTRMHLGHILLSHHGQREFGSPVVPATPEAMIVSSADELDFRMFCWHDSVKNLTEDQPISAWNNSTQRRFWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSF3</accession>
    <name>A0A010YSF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441350.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.180"/>
    <dbReference type="HOGENOM" id="CLU_692470_0_0_0"/>
    <dbReference type="OrthoDB" id="2117827at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457677" evidence="1">
        <location>
            <begin position="27"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="396" mass="41944" checksum="A1A0A21DD1726F13" modified="2014-06-11" version="1">MRAVKILLRVITLVVVLTVSSAAALASPAVSDNYQKIPLNGLNVGGTLVDDSVWAFPEPPDTELQNMIKEDAGNGLCQLLGNSEILTAWQAYCSASGSGGVILLETTDGVPPAVANDAKAFITRLDIDWSPKPPVSTYVLVEAVDGIAVDSANKTIAIKPAKTLSFEKDKPYAIFIAKGGPAPAPDHEPAKPFIISKDYEEYPVASIDVSVDEPLPAGISPANVKRREKGLDGWRGTINKYISTDDTLDSIDWPEGFKKDDLISLSALTAVGVTIDYDKETASDGDVTFHIRIGGFKGAFAGSPCVFIVDPGTKPYRLTAFPARYDAETATVTFTVAGYKKYFSFAIPIIGDVKLKSQPVPESPGSGGSSGGCSAAPWGVFITLGAAWLCLKARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSH3</accession>
    <name>A0A010YSH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0188</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709295.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.206"/>
    <dbReference type="HOGENOM" id="CLU_017959_5_4_0"/>
    <dbReference type="OrthoDB" id="1419334at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="471" mass="49379" checksum="049968D57A5EBA49" modified="2014-06-11" version="1">MAKKKLIYGIDDRPPTPILILAGAQHVLTLFGATTLVPLIFGPAMGMTTQQIGAFIGCVYFSMGIATLIQTHPKLGSGLPIVQGSSFSFIPPIMTIIGAYKSLGPDVIMQYVGGALVVGGIVLSLLGYSKLIGRIRKIITPVVIGPTIMAIGFSLAPTAIQFNAANFWPVSLLVVVMVFFFSLVSKNKYFNIFAVLGSIVIAYLLCLALSVSGVFAPGHPAYINLQSVYDAPWLRYRLFMPWGVPKFSGLAVGAIAAGFFCVMIESIGDYHNCSYAAGIDDPTPEQINRGIGAEGMCCALSGILGSVGTTSYTENIGLIGLTGVASRHVVRAGAVILILLSLIGKLGALIATMPSPVIGGAYITLFGTIGALGIQNLMRADMGSQRNVLIVGFAFLMALGLPGWVEPNQALFTGLFGTTFGGMIWAVLKTPMAVAGILAAICDNLVPGTPSERGILSGIEEAQENVKKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSK5</accession>
    <name>A0A010YSK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441395.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518667_0_0_0"/>
    <dbReference type="OrthoDB" id="1278465at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457923" evidence="1">
        <location>
            <begin position="24"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="492" mass="55995" checksum="DE0A1C466F3D5D43" modified="2014-06-11" version="1">MKRGFFLTLLLLCTLCAAPRAEAVKISIEIPSVRETVLASGRDFYVAGRIDREGVPAAELPVDIRVEVAEAGLMRDGVRIPLRAVESRVDKASGLTPRRDIWFRYEGKAPWTKLPPDELMASPPPDLVYRHGDPQSFYDPRLKAAVTENGYAALIQGGCTKDFDSGYKNLYKDDLEWKYFRVTVSAVSGGRVLAERHVDVMLGSVPDKMLARFSPAAHMKKVTDFAHEKGYRIYGDPFPGYWFRDLDGVYEIPLRWRLNDGLEYASGRVHAVLYNIPEKRSASQEVEFGRIAFEGRLFRDDEVWFYFYDAGEPSLKYSAWDGEHVKEGRITKLDEGERLRFTRAELGSRPEKYFPTENAGRVDWNVYDSVAAAPGEAVTFFGVTPPIQPPLSEVEQNDDGTFTIKNRIAKIRYRFEEKSLGEVIEKELPTGLERCYDPRDEKWTSPSIYEFRHTITLPGTAKKRLYTVTVEAFDSRGAPVDGTEAMFYLWVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSP1</accession>
    <name>A0A010YSP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP phosphoribosyltransferase involved in histidine biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709422.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025113_0_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA-synt_His" evidence="1">
        <location>
            <begin position="16"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="43616" checksum="B6978AE2389DAE4E" modified="2014-06-11" version="1">MNRNPKGCSNIGGAIAANMEYCRGAAMHLFSLYGYHPFSPAEFQLVEDVWSKIAPARARRLIPLMSPLGEPCVLRGDLTLTAVAYLGSHHTCSERPLRLSYADRIFSVPQPPKDNLEENQVGVELIGWEDTGADAETAVLLLRTLDLLSIERSALVLGDVSVLAGIFGGLPESRAGKLIEALQERAYTKYNMLLDGLALPEDKTLLLRRLPSLKGDVSVIGEAMGLFEDPSVLMPLKRLCDSLCKLGYAERLRVDLSFVRDLGYYSGPIYNAYSSVDGVLLGGGGRYDGLLAKEGIEGQAAGFALNLKELAAHCASPAPAPLMMLWGGSCANAEALRYADALSKKNIAFELSWTKDRKESLSTASLRGYKWWIDLGGRRVTLLPGGREISLNEFESEVLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSZ4</accession>
    <name>A0A010YSZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator with cupin domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441550.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_5_0_0"/>
    <dbReference type="OrthoDB" id="1069752at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="185" mass="20486" checksum="66F9912EA372A25D" modified="2014-06-11" version="1">MENINSVVADNLKRLRDERKLSLEATAKLSGVSKSMLGQIERGEANPTVSTVWKIAGGLKISFTDLMTRPEKDYETVDIRQVEPLLEDGGRYRNFPVFSFDAARRFEMLYVEIDPGGRLEAEPHPAGTQEFITAFSGELAVTANGEAFSIKGGGSSLRFKADTPHSYKNTGDEICRLSMIIYYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT13</accession>
    <name>A0A010YT13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GLUG motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484822.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_410341_0_0_0"/>
    <dbReference type="OrthoDB" id="1339371at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011493">
        <property type="entry name" value="GLUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07581">
        <property type="entry name" value="Glug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457931" evidence="1">
        <location>
            <begin position="26"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Glug" evidence="2">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="669" mass="68811" checksum="605D59D9B4A1DFF3" modified="2014-06-11" version="1">MSRKILFMFIALMAAFLLPAGSARAADWIESADVSWYEANSADVTFTINTPEELAGLAKLVNDGTQTFLNKTVKLGKDIDLGGKVWTGIGITGKTFKGLFDGQGYTVGGLGAIKCGAPGGEYIGFFGILNGGLTLNIRNLNVTGNVSVAPETIAGRDYLGYRVGGIAGWAQGAAATSSIENCSFKGSVKGYGDGYVGAIAGYGAMVLRNCSAEAYITTDNSGNDKNTTVTCLGGLCGNANQPIENCFFSGSIKNAEAVGPVSAGGIAGTTGTGAALTNCAVSCDIDVIGGQHPTVNINRAGYMNNAGGIAGVVQWQAIVGCSAQGSIKIRSAAAGDAFVNAGGIAGVKDNSQDLDFEHCSSVMKTDSSGHAGSLVGFIPEPTNIKMYQCEWLAGEGFPSDCYAADVDIPENRLKLSVTKVTDAAELTPVALISAPTVRILENQSYTQKAISFPSAAGKTDGLAWSWGTADSTVASIVSSVRESALVRGVKAGATYILASTNGFLGENSWTAKTYAAVTKVMLTSLALDAESVTLTGAGDSKIITASLLPAEEVSYPVLRWDLKVTSGDAAAVDDIELTHVGSSRQLKATLLKYVPGAQYLLSAYTVDGSELSADVVVNTAEEKAPDGGSHSSGGCNGGGYGWLSLFMVLPFAASVLKKRSAINGGKNHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT35</accession>
    <name>A0A010YT35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme involved in inositol metabolism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709122.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087290_0_0_0"/>
    <dbReference type="OrthoDB" id="1047507at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008880">
        <property type="term" value="F:glucuronate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024203">
        <property type="entry name" value="Deoxy-glucuronate_isom_IolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021120">
        <property type="entry name" value="KduI/IolB_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39193">
        <property type="entry name" value="PTHR39193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04962">
        <property type="entry name" value="KduI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="267" mass="29725" checksum="22477989E6FBFD08" modified="2014-06-11" version="1">MWSDNQKRMEKWRAQSPETPGFHAVIVPGKNECRAARVYRLNLRKGESFRLESGELEMHPVLISGSASLGCCEELELKTMKKFDSFYIPANTAVNITADEDCVFYIGAAPYDGIGAACFRAFDPDLPIGDIHQIHGEGMGRREVMFTLDPATPASRLICGLTWSANGAWTSWPPHQHEKDLEEVYCYFDMPAPKFGFHVSYLTSGGTMDCVAHPVQSGTMVEAPCGYHPTVSSPGTVNAYLWILASFSPEQRRYDLAKLDPQYEGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT38</accession>
    <name>A0A010YT38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484824.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.468"/>
    <dbReference type="HOGENOM" id="CLU_077795_1_1_0"/>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="209" mass="21838" checksum="52C1FAA8A19B26B9" modified="2014-06-11" version="1">MDIYKQIEALKIVPVVKLDAAEDAVPLAKALIDGGLPIAEITFRTAAAEESIRAVSVAFPQMLVGAGTVVNVEQAERAVKAGAKFIVSPGFSPAVTKFAVEKGIPIFPGVCTPTEIMAALEFGLKVVKFFPAKQYGGLATIKALAAPFPGIRFMPTGGVSAENLLEYLSSDKVIACGGSWMVKESLIGARSFGEVARLTREAVALAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT55</accession>
    <name>A0A010YT55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcription factor, MBF1 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484829.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1668520_0_0_0"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="173" mass="19278" checksum="A0E6B9A5A8676934" modified="2014-06-11" version="1">MTPENVGVNIQTAREKNGLSRSALAEVIGVRANTVWRWESGERQPDIDNLYKLAYALKTSVAFFTGEVSDPDLLSSDLDKIINTYVKKQDESELKLPGSSATSKWDTPATQQTDHTKPSQIIETIARVNREIEAETKAFEEEEIDIAQILLKRCLKTLEKESSAYAGDSEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT66</accession>
    <name>A0A010YT66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441695.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_0_1_0"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="18071" checksum="E7F94C6CA903254A" modified="2014-06-11" version="1">MSRGYNKVILSGNIVRAADVRMTAGGQKSARFTLAVGRSWKDKATGEKRERADFISCVAWGPTADLIEKYTDKGKSLLLEGRISVRDFDDVKSGTHRWVTEVIVTEVVLQGGAAGRDSNSAHDGYGDARPGGPRDLGYDKPDLFEDDFPIDFSELGGGSDEIEIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTB8</accession>
    <name>A0A010YTB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441776.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.570"/>
    <dbReference type="HOGENOM" id="CLU_081840_1_1_0"/>
    <dbReference type="OrthoDB" id="1687413at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="211" mass="24395" checksum="76B18766CBE20DED" modified="2014-06-11" version="1">MIKIRNERETDYKTVEDITRKAFYNLYIPGCAEHYLVHIMRGHEDFIAELDFVIELDGQVIGNIMYTKAKLIDEAGTKKETLTFGPVCIAPEHQRKGYGKMLLEHSFQEALVLGYDAVVIFGSPVNYVSSGFKSCKKYNVCLENNKFPAAMMVKELTPNVFDGRKWTYYDSPVMAISEQAARQYDDALEKMEKRYQPSQDEFYIMSRSFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTE5</accession>
    <name>A0A010YTE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0568</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484842.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.609"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="309" mass="35054" checksum="6B69E7BDBDBF0507" modified="2014-06-11" version="1">MNLLNMRYFIEAAETLNFTKAANNLNISQQALSTHIAALERELDAELFIRSVPVTLTQGGLLFKKYAQRFLDEYSSMIHEMNDIKDERRGALSIGIAHTRGRILLPRILPHFQRAFPKVDIKITEGRNDEMQKSLSEGKLELLICKLPVIGANVRSEFFYQEKAVLMVSDALLEKYFGAEKDAVAKEIERTADIGPLEKLPFMLPHRGDLMRAVADELIGRAGFIPDIIVESENIETLLEMAVRGIGVTFYPKMFIDYSGFINFPDAFHIIPLNTPAAAYSMGFCCPKERYLSFAAREFIRIAKENIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTH7</accession>
    <name>A0A010YTH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484852.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.649"/>
    <dbReference type="HOGENOM" id="CLU_022426_4_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="232"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="573" mass="65176" checksum="BAD386ABCE79B7B6" modified="2014-06-11" version="1">MRLNTRRSNGVEYVYFLESYRDPVTKEPRTRTVKSFGRRDVLEARDPDIMSKLQAECDRINAETSTSVEEKLAELFKKAPADPVCEGLSLKNYGIFCYRALWNELSMDVCFRGIQSLSRSKCDLARSAFFLSALRNMQPCSKVASFRQKDSYLFNFGSLRLDDMYRSLNMFADYKSKIEAHLYKKLFNGEKKNVSVAFYDVTTYYFESVEADGFRNFGFSKDHRVGEVQVLMGLLIDKCGIPLGYELFPGNTSEFKTLLSSLNKLKKQYKVEKVIVVADRGLNSKSNLARIKEMGFEYVLAFKIRGASDDVKAAVLSKDGFTECLKEGEEDSCRFKVLEHTQVVVCPDEDGGRNKIYLTDSLIISYSSKRAEKDAKDRGRLIKKAEKLVANPSMFKAELKKGGKSFVAADIDGNSLKLDAAKIAEQSLYDGYYGILSSDPEISPEEAVSIHHGLWKIEESFRIMKSGLRSRPCFVWTPEHIKGHFVICYLALVLQRLLEKKLKERGIAGSSQAIQDSLNKANVMELRIKGQIFYAKEKTPKLYDEIADTLGIAPLRTYSTKTDLQKHFRHRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTI2</accession>
    <name>A0A010YTI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0613</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710352.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_3_0"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="15"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="229" mass="26657" checksum="57DA7B40C9B0E759" modified="2014-06-11" version="1">MAIKLDTELGMEPSSTLRTEVANLLRKQILDGDIPCGERLIETEIASQLGVSRMPVREALRMLESEGLINQVPRKGLIVAEYTENDIREYYTIREALEVCAIKIVIDKISKDELEELKMYCRKAEEAHAHDDIEAVCRWTAKFNDRIYDSCEMPRLKEQIKTTQKYLRTFRFTSFKEATRTEQALKEHAEIIRLVEKKDYEGAALATSVHLRDAMQAYIRLWRQRKGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTJ2</accession>
    <name>A0A010YTJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tripartite ATP-independent periplasmic transporter solute receptor, DctP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441871.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.669"/>
    <dbReference type="HOGENOM" id="CLU_036176_1_3_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458844" evidence="2">
        <location>
            <begin position="24"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="329" mass="36292" checksum="44F56DC9751593FA" modified="2014-06-11" version="1">MKKFLVLAVIAAAITSFSPQAFAVTKMKLAYVVPEAQSTHVAAVKFFKPYVEKHTNGAIIVELYPNGQLGGDRQVIEAVGLGTIHMTIPAVAVLSGFDPRFQVFDLPFLFNSRQEVYRALDGELGSKLNDLLPPLGIKNLAYAENGFRMITNNRGPVTKPADLKGLKIRTMENPIHMATFKALGANPTPMSFGELYTALQQKTVDAEENPIPLIYTSKFYEVQKYCSLSGHVYAATALLVNDAWFNGLSKEHQKVLSDAAIIYRTEQRKISEQQDKEMIEALKKNGMKVNDITPEQKKAFSAATAGVYKEFAKSVKGGQELLDLAKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTT7</accession>
    <name>A0A010YTT7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441960.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050189_0_0_0"/>
    <dbReference type="OrthoDB" id="313921at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="7"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="431" mass="46415" checksum="76884C3BD465D4E9" modified="2014-06-11" version="1">MKYSIPYGNSFLDFDTYTNRVLFSGEMTDVPPVTDIRAELFRSLDAPIASEPLAALAKDKKNILFLVEDNTRDTPLTKILPVVMEYLDAAGVPRSAVSFMTAPGTHRLMSDKEVREKLGDYIVDNFTVYQHEASNTDELADLGEIEAGGYKLPVRINRRALEADLLVGVGNIIPHSDAGFSGGAKIVQPGICDFVTTQATHRGAGLCPDIPLGMLEGNPCRMGIDAVGGIAKLAFIVNVVKNFSGEIAGFFCGDYLKAHRAGVELAKRSYSVELDELADVVVVSSSPADMDYWQGIKGLTSAYFAVKPGGAVILAAPCYEGLVHNHPLYAHWLAQPTEALVEAIKGASPYDLETDVISAVVALGSRRVLDRAEVYMISDGLSREEIEKMDYIPAANVQEALDAALAKRPRATLGILPLGGISLPILTKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU07</accession>
    <name>A0A010YU07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710678.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2463625_0_0_0"/>
    <dbReference type="OrthoDB" id="1925914at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="88" mass="9359" checksum="278951F416FDDE34" modified="2014-06-11" version="1">MINEELIAEIVTRVIEKLAALENAPCAAAPETGKDAGEIKIEKRVITEKDIIAARGGGASAVCVARRAIMTDLAKEYAQAHGIVIKRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU43</accession>
    <name>A0A010YU43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="4">1.5.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0806</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442035.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_0_1_0"/>
    <dbReference type="OrthoDB" id="1349288at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="2">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="3">
        <location>
            <begin position="159"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="272" mass="29166" checksum="03D2AB506A3EE16E" modified="2014-06-11" version="1">MKIGFMGSGAIAEILSQKITASGTAKPSDIFIYDVSVERLAYMNEKYGLSICGEPKDMIAAADYVFMCVRSDNAIDMAKTLNAYDFTSKTIVSISSGIPMALYENNVPGAAVARALPNPPSRIGHGVIAVAFNSRVSEPQKADLMKIFGAMGTCLALGEEKINAITSLTGPAPVYAFFQGIVESALLLGIDHKTAAKMAFGTVEGCLKVWENNIDNIGGLLAETSTPGGISVRQLYNLEQNAFKATVKECYEEGYLRTKAYSDGILEMLNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU49</accession>
    <name>A0A010YU49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Saccharopine dehydrogenase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710745.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032858_3_0_0"/>
    <dbReference type="OrthoDB" id="1006830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Sacchrp_dh_C" evidence="2">
        <location>
            <begin position="125"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="392" mass="43743" checksum="A38E30EC02CACB73" modified="2014-06-11" version="1">MATKKKALQIGAGMVGRCIVHDMISDFDFVVLDMSEENLAETKRLYPSVETVIGSATDKDLIAKLSADCDIITAAMPGTVGYLVTQIAMELGKKISNVSSMHGRSDEPYDKIGQETGGLGISMIGFEPGMSNFFGGRGYYKLDKCEEMYVYVGGGLPVNPRPPFNYFTTWSISDNINQFNQPTTVVRGGKEMVIPALSEVMHFEIEEFKNLECFTSNGLGGLFRSFKDVPEMAAFTVRWPGLAAQMRFLNELDLFDKEERMLGKVKQVPRDILIDIFSKKYERLPGEVDMSVLKIVVKGIKGSDRVTYTWEIAQKEIPGTGYTSMAWTTACTCGIFARAMTNGMLTGKGMLAAEKLAKDDDFYNWVMAEQAKRGIFYKEKVEVEKNVNLWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU99</accession>
    <name>A0A010YU99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710824.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2272480_0_0_0"/>
    <dbReference type="OrthoDB" id="2150515at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="102" mass="11840" checksum="1585873F524E7FAF" modified="2014-06-11" version="1">MLTKTLKVETDNHLNIMESVKKLAASSGQPLIVIDGEGTLLYINVLGKEVLKKKGRSRMMRKIFSFFSFVSYLAYNDNYYEMERIADFRTKENSLHICRIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUF9</accession>
    <name>A0A010YUF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease component of ribose/xylose/arabinose/galactoside ABC-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710910.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.970"/>
    <dbReference type="HOGENOM" id="CLU_042763_1_0_0"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="363" mass="39579" checksum="FD6313B7733A9DDD" modified="2014-06-11" version="1">MAKRNRELKSMLADYAVPIVFIGLSAIAIPLSGFSATYLIQEMFTRLARNSFLVLSLLIPILAGMGLNFGMVLGAMAGQIGLIFVTDWAVVGWEGMLLASIVGMPIAILLGYICGAVLNRAKGREMVTSYILGFFINGVYQLIVLYGMGNILPISNPQLVLSRGYGIRNAINLTGVRHVLDNLIPFKIGTIDVPVATFILIGIFCLFIVWFRRTKLGQDMRALGQDMAVAESAGIPVERTRIIAIVISTVLACFGQIIFLQNIGTMNTYNSHDQAGMFAIAAILIGGASVSRATITNVFVGVVLFHLMFVVSPMAGKELIGQAQLGEYFRVFVSYGIIALALVLHAWRRQRDKIEARRSLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUK4</accession>
    <name>A0A010YUK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal protein HS6-type (S12/L30/L7a)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710979.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168063_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_L7Ae/L30e/S12e/Gad45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L7Ae" evidence="1">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="81" mass="8601" checksum="757DDD3C55521C86" modified="2014-06-11" version="1">MPLNELASSPRCAGQNSVLRNIARGEALKVFLAADADEKLALRIRAASNERNIPVETAADSQQLGRACALTRKTAVAAILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUL7</accession>
    <name>A0A010YUL7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="6" type="ORF">Cloev_0988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710997.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1058"/>
    <dbReference type="HOGENOM" id="CLU_073626_1_0_0"/>
    <dbReference type="OrthoDB" id="2035880at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="11044" checksum="4C7C8BC59637B41A" modified="2014-06-11" version="1">MEERKAHRKVRTGTVVSDKMEKTIVVRVDRMAKHSLYGKPVLRSKKFMAHDETNDCRIGDTVKIGETRPLSARKRWEVLEIVERAPILGVAEEEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUU7</accession>
    <name>A0A010YUU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442398.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_32_1_0"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="307" mass="35580" checksum="67AF128EBE12E187" modified="2014-06-11" version="1">MNILQWEYAIEVARLSSINKAAEKLLVAPPNLSRAIRELEEDLGIVIFNRSYKGMTLTPEGENFIGYAKRIIGQINEVEYMYKSGASVKQKFSVSVPRASYISDAFARFSTCVSAEQAEIYYNETSSLHTMDSVISSEYDLGIVRYAKKFDKYFEKSFEEKGLLYELITDFHYVLIMNRDSPLAAQDAIRLSDLTPFIEIAHADPFVPSLALSAVRKEELPEEIKRRIFVFERASQFSLLLHNKETFMWVSPVPNQLLEQFQLVQKECADNRKTYRDVLVHRKDYPLSELDRRFITELIRAKRRCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YV04</accession>
    <name>A0A010YV04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retron-type reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1222"/>
    <dbReference type="HOGENOM" id="CLU_636970_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="448" mass="51823" checksum="20BF8A42294468C7" modified="2014-06-11" version="1" fragment="single">PSIAHTENAGEERAQTLLECILTRANMAEAYKRVVKNGGASGIDGMTVQAMYGHLKEHYPELIQSLYDGSYRPQAVKRVEIPKADGGKRKLGIPTVIDRMIQQAISQVLTPIFEKQFSDGSYGFRKGRSAHQAIEQARIYYEQGYKVSVDIDLAKYFDTVNHNLLIKMLREEIKDERVIRLIRKYLKSGVMENGLISSTTEGTPQGGNLSPLLSNIYLTKFDKLLESRGHKFVRYADDCNIYVKSARAAQRVMGNCVNYLEGTLKLKVNQKKSCIGSPTKLKFLGFSLYPSKGETKIRAHEQSLKRFKDKIRKLTARNQGRSIETIMLNLRKYTTGWLGYYAIAEMKSAMLQLTGWIRRRIRQIYWKQWKRIWPKYKNLRQLGIHHRDAWRWANSRLGCWHIARTWILTTSLTNKYLASQGYDDILLRYEAMRARYRTAVYRTVRTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGU5</accession>
    <name>A0A010ZGU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="9" type="ORF">Cloev_0049</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.58"/>
    <dbReference type="HOGENOM" id="CLU_009678_5_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="426"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="559"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="587"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="687" mass="78071" checksum="EA4F3D8EE33700EB" modified="2014-06-11" version="1">MIMNNRELSWLVFNDRVLQEAQDKSVPLMQRLKFLGIFSNNQDEFVKVRVAKLIRLSRLKGLKGAQAAKARAAAEVLPLLYARMSESQEKFDEIYYGILAEMAEIGINVVNERRLTEGQEQFCADYYASVVSERIVPLLIRKTTKMPFIGDGDIYLAVKMTGGKGKNVRYAFIQIPVSSACPRFVELPSAEGRRDIIFLDDIIRLCLREIFFMFSCETISAHTFRVVRDAQIEMDGDISKSLMEKMEEGIENRYRGNPVRLIYDRDMPEDLLSLIVSKLSLKLGPSLDPGGRYHLKRDLMKFPRVCPRLEEKLPAPMRHPAIAPFAGVFKATAKRDVMLHFPYHTFNHVIDFLREAAIDPKVESISITLYRTAEHSKVINALIGAAKNGKRVTVIMELLARFDEGQNIEYADILQRAGVRVIDGVAGLKVHCKLILAERRERGGVKGYAYIGTGNFNESTAKIYSDFGLLTCRREIVSETRAVFDSIVSHKPLSCKELLVAPYNMRARFEELAEEEIKQAKKGRKAYIKAKFNSLTDPEMINLLYRASRAGVRISLIVRGACCLQPGVEGLSENIRVISIIDIYLEHARMAIFCGGGEEKYFILSADWMTRNLNRRIEVGTPVYDPAIRRQLKKVFEMQWGDNVKARDMAVFGANEYVKGEGKERCRSQLALHDFYKKAAEKGDEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGY3</accession>
    <name>A0A010ZGY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin biosynthesis protein CbiG</fullName>
            <ecNumber evidence="3">3.7.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441275.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.102"/>
    <dbReference type="HOGENOM" id="CLU_028397_0_0_0"/>
    <dbReference type="OrthoDB" id="1617773at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043779">
        <property type="term" value="F:cobalt-precorrin-5A acetaldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021744">
        <property type="entry name" value="CbiG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002750">
        <property type="entry name" value="CobE/GbiG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036518">
        <property type="entry name" value="CobE/GbiG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038029">
        <property type="entry name" value="GbiG_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01890">
        <property type="entry name" value="CbiG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11760">
        <property type="entry name" value="CbiG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159664">
        <property type="entry name" value="SSF159664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159672">
        <property type="entry name" value="SSF159672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiG_N" evidence="2">
        <location>
            <begin position="48"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="CbiG_C" evidence="1">
        <location>
            <begin position="189"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="312" mass="32670" checksum="4FB179281CE92ECD" modified="2014-06-11" version="1">MKLHAAAFSERGAELALRIARAFGGAAWAPEKYAKNGVLPFGASLGEWTGARFAEAEALVFVSSCGIAVRAVAPHLRGKDKDPAVIVADERGLNVISLLSGHLGGANELALRVAGIVGGRPVITTATDVNGITPPDSWAVQNGCAIENLPAAKRVAAELLAGHAVGVAVTDELQPAPYPVTLWLRPKDLIVGVGCKRGTEPELLREYFSDFMKESGYSALSAAAVASIEQKRDEAAIAGLAEFYNIPFETFSAKELMALPGEFTPSPAALAAVGADNVCERAAIAASRGGYMVRLKTKYPGVTFALARKRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH62</accession>
    <name>A0A010ZH62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034444977.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.175"/>
    <dbReference type="HOGENOM" id="CLU_029381_0_4_0"/>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="348" mass="37655" checksum="A82B9903DA190771" modified="2014-06-11" version="1">MVKSDFRSDTSTRPTQSMLQAMLLAECGNEGYGDDPTLNELERRASVLFGKDAALFMPSGTMANLVAVMSHINRGNEVILEADSHIITNECGGLCVVAGAIPRILPGEKGVMDLNKVEGLIRKQSFKTPSTGLICIENTHNKSSGSVLPMKYITDISALAHEHDVPVHMDGARIFNASVASSTPVKEIAAPVDSVTFCLSKGLCCPAGAMLLGRKAFIDEARRNKKMLGGIMRQTGILAAAGLIALDETVERLQDDHNNAKLLALKLAEINDIFIDINSVQSNMVYFKINVSESKCLNIIQYLKNNGVLVDYKGGGSVRMVTHKDISEQDINKAIRQIISAINTIHAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH91</accession>
    <name>A0A010ZH91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative esterase of the alpha-beta hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0189</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.207"/>
    <dbReference type="HOGENOM" id="CLU_014750_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459045" evidence="3">
        <location>
            <begin position="27"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="127"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="131"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="158"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="305"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="803" mass="88591" checksum="F7C18AC0455C9E0E" modified="2014-06-11" version="1">MKQIFKNKIILYMFLILLTVTNWAGAADASAGLPPEEVLTVRQGEQGAAHAADASAGLPPEEVLTVRQGEQGAAHAADASAGLPPEEVLTVRQGEQGAARAQFERDSPETRAHMQSWGFPHKEGVVLVLCGGGMKGLSHLGVFEVLEREKIPVAAIIGTSMGSIMGGLYASGRTPEDMREVLSKVDLMEIMSGRNRSDLINGYNKPAVPGDSLFSFTIDKNKNEQGRLGALNAKDLYAFLSDLTSHVSVTDFDHLPIPFAAVATNLGNGDTVILRNGNLASALRASMSIPVVFDPWPMNGMLLVDGGLKANLPVLEAKKIFPGHPIVAVNLSPEDITKKNENFRTMFDVAAQTLDILMVQQIRQNVEAADLVITPEVSGFSTFASGGYDKIIDKGMEAAEEKVPELKKLVEEKCHTWDHSRVERTRRYGPPVVAEVRFEGVPEGVAEELHEKYEDWIGKPLDMRLVADTVTQISTRDDIKSVDGRTENISRGSVAVIFQIERPAKYEFGVDGYASNLYWNRWISLSAVVHDTLMAGDSASLEFRFGTTWGAMMRYFTVEDEKDSQWGLVLAGRREEYEPYNYGNAEFERYTAKAAWYKKLNGRLRVGLGYGAQRVTSLGNDTINDHGPYFTFSFNTLDDPILPTKGMVVMSDLWFPIDHNVVSNTQFRTYVPFLKMGKVIFAGGLKTGDADSLAYAAMLGTREELYSLGQHPLVGDQAYWLHLGIERVFTRSWWGGVNVEIFGNYGQTMYDWKNADSRWEVGAALSIPTNNFSSKLVFVYDDDGGFTIGYTIGVPRFWDGPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHR7</accession>
    <name>A0A010ZHR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative regulator of cell autolysis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484811.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020473_1_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="508"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="603" mass="67274" checksum="82F3F6582F4B8B50" modified="2014-06-11" version="1">MKNILGKIRFSLLAAAVIAAIFIIGGLFSGGGRLAVKGALSHISIDGEYRTEGSAWRPLSGLSEFRGAEEGRPVYIKGHFREEIAINRFVILRMVNLRLRLSVNGRELYSFGYSGRPNRYINSPGDVWHGFLSPGISPRDEVTIELRRVHAKDYDSPVKLLLENIYAGDSGELLLDVLYRRIGLLFFIGIFVPLLGAVELLASPLLFFFASRNVFLRFFYNAGFTFAAGGWISINYDISTLLVPFPRVILAFEVTCLYLTAFFFASYAATYMSGWRRRAAECSAAAGLFIFLALAALSWTGTTDIYRPMLFSAAVNTAFFLFAIVSLVIEYRKSGDKAILPVLISFVPTLFGAIADNLGYLRIIETPPIWVCVSFSFFIIIQSVILIWEYKRRADADARAERMEKELAESKVTIMLSQIEPHFLYNSLSTIKALCAKDPKAAAEAVSHFAKYLRGSMASLSDKKPIPFDDELRHLENYFYIEKLRFGRRVELIFDLETTDFMLPILTLQPLVENAVRHGRGDGRGTITITVATKRLANGSLLSVSDDGSGFNLQTLARDGSRHVGIENTRNRLEYLCRGRLTVESRPGTGTTIIIFVPHEGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHX5</accession>
    <name>A0A010ZHX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">Cloev_0406</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441618.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.449"/>
    <dbReference type="HOGENOM" id="CLU_029848_0_0_0"/>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="40"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="301"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="14"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="333"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="415"/>
            <end position="417"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="428" mass="46646" checksum="4806733A410780E5" modified="2014-06-11" version="1">MKGRTDIVLGVQWGDEGKGRVVDVLAARAGVVVRYQGGANAGHTVIVGNEKYVFHLLPSGILYPGKTCVIGNGVVLDPETLFEELDDLASRGKRLARLVVSHGTHIVMPYHKMIDRLAEGARCEGTKIGTTGRGIGPCYADKYERIGIRAEDLVNPEILKDKLERTLKIKNDILTKIYGAEPLDFEEIYDRALKWGERLSPMLGESFLEIYDAVRAGENVLFEGAQATLLDVDYGTYPFVTSSSPCAGGACTGAGIGPSRIDRAIGVAKAYCTRVGEGPFPTEELGETGELLRSKGGEFGATTGRPRRCGWCDLVAVDYAVKVNGLDGIALTKLDVLDGFDEIKICTAYEIEGEARKHFPSSCAELAKAKPIYETLPGWKSDISRCRRFEELPKEAQDYVRFIEERVKAPILLIGVGAGREDTIERGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI48</accession>
    <name>A0A010ZI48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441749.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1400364_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="194" mass="20451" checksum="D99D28667E7F7596" modified="2014-06-11" version="1">MGGGGGSSHSETVRKRDPDSAEISALQSLLYSQYTPMASQLGGDYAAAKENAAKYGQQYDKAYGGLADLTESGNLPAGLTDAMNGYITRSMDKSLGSAMAQMGGKGILNSSVTGRAINEIGSNTADAFAKNYMDAYKAASGNYGTLMDAAGSAQKQQYDNLTAQYAPLMEFFKTVRASEDQDDYDTVVYQDGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI58</accession>
    <name>A0A010ZI58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease component of ribose/xylose/arabinose/galactoside ABC-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709618.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.550"/>
    <dbReference type="HOGENOM" id="CLU_042763_0_0_0"/>
    <dbReference type="OrthoDB" id="1155165at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="348" mass="37284" checksum="3D758C8148D5FEE0" modified="2014-06-11" version="1">MNDKLRSFIESAGWPRIIIALFLLSLFIAAPFVGVRIDASLSDTLVRVGMNGILVLAMVPMVQSGCGLNFGLPLGIIAGLLGAVTSIQLGVAGPAGFLAAIGIAAPIAAAFGWLYGQLLNRVKGDEMMIATYVGFSSVALMCIAWLLLPYTSPTMIWGYGGSGLRTTISVEGFWLNALSKYLHIQIGEFFYFPVGMYIFFILTALTVHGFFHTKTGTAMTAVGSNPEFARASGINVDRMRTISVILSTLLGALGILVYEQSFGFIQLYMGPFYMAFPAVAAILLGGASVNKATIVNVVVGTFLFQGILTMTPSVINSVMQTDMSEVIRIIVSNGMILYALTRKVKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIT7</accession>
    <name>A0A010ZIT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441967.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_0"/>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="23"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="327" mass="34897" checksum="5133A785C2A0D266" modified="2014-06-11" version="1">MDKLPINPGITDVVKAYKFLKSRVRRTPTEYSYALSERAGAPVYLKLENQQLCGSFKLRGALYKMNSLSPEERALGVVTCSSGNHGQGVAMAARELGIKTWIFVPDTCPETKKEAIRRRGGDFTELVVADGDYDFTERAAHEYAESLGITYVSSFEDATVIAGQGTAGFEMFMDEPEIELLLVPAGGGGLMNGVAIAAKALNPNVEIWGVQTDTSNPWVVSWEGGSVKEVEYGETLADGLAGGIPQSLLSLAKLRVKGILEVTEKELAAAIAFMHREQHQVIEGAGAVGIAALLAGKAPVGGRRTGIVVSGGNIDEAKLLKVLAENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ49</accession>
    <name>A0A010ZJ49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycyl-radical enzyme activator family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0822</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442052.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.874"/>
    <dbReference type="HOGENOM" id="CLU_058969_0_0_0"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040074">
        <property type="entry name" value="BssD/PflA/YjjW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01118">
        <property type="entry name" value="activating_enzymes__group_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="312" mass="34477" checksum="A1B458EF90C9B76F" modified="2014-06-11" version="1">MEKGNVAGTVLRIEKSSIHDGDGLRTVLFLKGCPLRCLWCSTPESQRGAPERGLAREKCTLCGRCVQACPHGALSKKDNKITHARDKCAGCLKCAAICPESAITPYGKTMTAAEAVKEIAKDEIFYFHSGGGLTVSGGEPLEQSGFVLEILRGCRERGIDCALETSFFAAWEKIEPLLPYISLLHVDIKHPDAEKHKKLIGVDNRLILENIGRADAFPHNFGIVVRTPLVPGINDADEDIAKLAGIVKRLKKLRFMEFLAYHRLGTETYKRLEIPYPLAEINTPDDSYMRRKAAIFKTAAGVEVRINGRIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ59</accession>
    <name>A0A010ZJ59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cysteine desulfurase IscS</fullName>
            <ecNumber evidence="7">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">iscS</name>
        <name evidence="10" type="ORF">Cloev_0832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710780.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.885"/>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_0"/>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="UniPathway" id="UPA00266"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017772">
        <property type="entry name" value="Cys_deSase_NifS_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03402">
        <property type="entry name" value="FeS_nifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="6"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="7">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="7">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared with IscU</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="392" mass="42397" checksum="B3EFAD76F3BA63C5" modified="2014-06-11" version="1">MAPREVYLDNSATTKVDPRVTEAMLPYFSEKYGNPNSLHKFGREARAAVDNARAQVAALINAKPSDIIFTGAGSEADNLAIKGAAWALKEKGRGNHIITSAVEHHAILDTVKWLGKMGFEYTILPVDDKGMVSPADLEAAIRPETILATIMFANNEIGTIQPVKELGEVCRRRGVMFHVDGVQAAGHIMIDIQQLPVDMMTMAAHKMYGPKGLGALYVRKGIKLIPTLHGGGQEFGLRSGTENVPGIVGFGVAAEIAKERLARGDDKKLARLRDYFIDGVLSRIPESHLTGAVGDDRLPFHTSFTIKYIEGEGMLLLLDAAGIAASSGSACTSGSLEPSYVLLALGLDHTTAHGSVRLTMSHDTTKEDIDYVLEKFPAIVEKLRAMSPFYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJF4</accession>
    <name>A0A010ZJF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arginine/lysine/ornithine decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445330.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.961"/>
    <dbReference type="HOGENOM" id="CLU_025925_2_1_0"/>
    <dbReference type="OrthoDB" id="485164at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00615">
        <property type="entry name" value="Orn_deC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008286">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03711">
        <property type="entry name" value="OKR_DC_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="SSF55904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00703">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="3">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="487" mass="52932" checksum="2EE475EF0BC882F3" modified="2014-06-11" version="1">MKERTYKLAQERAPLLEALAEYRKSRVVPFDVPGHKQGRGTPELTEFLGKACLSVDVNSMKPLDNLSHPTSVIKEAEALAADAFGADDAFLIIGGTTAAVQAMIMSVCKRGDSIIIPRNVHKSAINALILCGIAPIYVDPGIHPELGISLGMCADDVEAAIAAHPEAKAVFVNNPTYYGICADLGRITEAAHRAGMAALVDEAHGTHFYFASDMPLTAMEAGADMAAVSMHKTGGSLTQSSLLLMKRGRVRPDYVRTVINLTQTTSASYLLMSSLDIARKALATEGKETFSRVVSLAEYARGEINKIGGYYAFSREIIDGKYICGFDTTKLSVNTLKIGLAGVEVYDLLRDDYGIQIEFGDMGNMLAIISVGDNHYAIERLVASLSEIKRLRGREGLHLLDHEYIPPVVRMTPQEAFYAPSRPLPIREAVGKISAEFVMCYPPGIPILAPGEEVTREALDYILYAKKKGSLVMGPQDMELNDLYIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJG3</accession>
    <name>A0A010ZJG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710912.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137433_1_0_0"/>
    <dbReference type="OrthoDB" id="1549660at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="163" mass="17856" checksum="E1C28A96A4A8D4B9" modified="2014-06-11" version="1">MTHNINKKRLIIRLALVALLVLLCFVLYYVGKEHEVLIDNKTAAIDGHEYQEIAYMNVVVDGDEDKAMEFYAGDRDVVKLKGPSHRIKITVINEDTEEVIKTVERDLSLGAVSSVMYSLPAIVDGAPTVELPLPHTEAQEESGGGDAPQQEEVPTGEAPALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJH1</accession>
    <name>A0A010ZJH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0919</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_3_6_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="159" mass="18080" checksum="A6ABE0FBB636804D" modified="2014-06-11" version="1">MKKSMLCKFVDRFEEATCLIALSMSVVVLFVNVVLRYCFRTGFAWSDEAVRYLIIYVTMIGLGMGIRNNATISVDLLLQMSSESSKRILHIVIFAIQIIFGMVMTFASSKLLLMSWKMNEHTLAMDIPIIIPYSPLLIGSLLVIYRSVQELICVLKNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJL5</accession>
    <name>A0A010ZJL5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 9">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplV</name>
        <name evidence="10" type="ORF">Cloev_0984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6 9">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710989.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1054"/>
    <dbReference type="HOGENOM" id="CLU_083987_3_3_0"/>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="110" mass="12299" checksum="247E606AE8DF2589" modified="2014-06-11" version="1">MEVTASAKQIRISANKVRRVLALVRGKNASEALMILKYTPNKPARYAEKVLKSAVANAEHNHGLDMDKLIVKTATADQGAYMKRFRPVSMGRAHAFRHHTCHITMVVCEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJP2</accession>
    <name>A0A010ZJP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbamoyl-phosphate synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="5">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_1019</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711044.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1088"/>
    <dbReference type="HOGENOM" id="CLU_000513_1_0_0"/>
    <dbReference type="OrthoDB" id="48855at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="132"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="670"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="13">
        <location>
            <begin position="928"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1045" mass="113398" checksum="E6C0566CCAE49F0A" modified="2014-06-11" version="1">MRDTTIKKVLVLGSGPIKIGQAAEFDYAGTQACRALKEEGCSVILLNSNPATIQTDNSVADFVYIRPLLPYVVENILREHRPDGVVATLGGQTGLNLCMECEKLGMWRRYKCRVLGTQPEAIERAEAREPFRRAMIEANQPIIASRGISSVAEAQEFALRTPLPLILRPDFTLGGSGNSVVRDIESFVVQTEDALTASPVGRALIERYLEGWHEIEVEVVRDNAGNSLAVCSMENIDPMGVHTGDSIVVSPVLTLTDKEWQMIRTAALRIVDVLDIRGACNVQFALAPDGGEYYVIEVNPRASRSSALASKATGYPIARMAAKIALGLNLTEMANPVTGAGSALSEPALDYVAVKVPSWPFDTFPQADPSLGPRMKATGEVLALAANFAQGLVKAYRSLARGRTLPDRKLRAWETRRLWEQVNTPTNLRLEAITELLRRSSATVEEMARRTHIRRYFIEQLNAIQLAEKYLEEDGAVNGNIVSAAKKGFSAGQIALAADISREEVLRRLEEEDYSTGYREVDGCAGEFPSGSGYYYGVAGVKDDPYERHSGGIAVIGSGAIRIAQGVEFDYCCVKAVEALRRRGIRAIMMNVNPETVSTDHDISDALYLEPLTVDDALPVLKREEAAGVFACFGGQTSLRLGLDLAQEGIKLFGPGAEVIDAAEDRGKFSRLLTKIGVPEPEGVDVASVEEAKEVGRRLGYPLMVRPSFVIGGVAMKVVYGEQALVEVLREAFEAVPGQKVMVDQFLAGREFECDAVCDGEDVLIPGIFEHIDPSGIHSGDSIAVFPSYSLTKEQQGQVLDFVKVISKELDVHGLLNIQFVLRGGVFWIIEANPRASRTVPIVSKISKLPVIDMAVGIALGERLRDMPYGTGLYPETGQWSVKVPVFSNDKLPGLDPKLGPRMMSTGESLGVADNLADAIMDGLKGSGWLPPATGRILMSIADSEKAEAMPVASQYKMLGWEIDATEGTAAYLKKWGIEVNRVERAELVRRLRGGEWDLVLNIPGGNERHMADGAMIRKQACSAGTPCLHSIAAAWAVAAGLNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJP5</accession>
    <name>A0A010ZJP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Indolepyruvate oxidoreductase subunit IorA</fullName>
            <shortName evidence="14">IOR</shortName>
            <ecNumber evidence="3 14">1.2.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Indolepyruvate ferredoxin oxidoreductase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Cloev_1024</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:12645"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17640"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57271"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="EC" id="1.2.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14 15">Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of the IorA and IorB subunits.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.8" evidence="3 14"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442316.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1094"/>
    <dbReference type="HOGENOM" id="CLU_017727_0_0_0"/>
    <dbReference type="OrthoDB" id="342322at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043805">
        <property type="term" value="F:indolepyruvate ferredoxin oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045025">
        <property type="entry name" value="HACL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017721">
        <property type="entry name" value="IorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710">
        <property type="entry name" value="PTHR43710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006439">
        <property type="entry name" value="Indolepyruvate_ferr_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03336">
        <property type="entry name" value="IOR_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 14 15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="16">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="16">
        <location>
            <begin position="558"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR006439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR006439-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXG78879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="587" mass="63532" checksum="56E893D2067F0A6D" modified="2014-06-11" version="1">MKKIMTGNEAIARGAWEAGLHVAAAYPGTPSTEILENLSGYKDVYSEWATNEKVALEVAAGASMAGARALAAMKHVGLNVAADPLFTLAYTGVGGGLVVVTADDPGLFSSQNEQDNRFYASHAKLAMIEPSDSQESLDFIKEAFAISENFDTPVLFRVSTRICHSKTLVEPGERAEVAVRPYEKNSAKYVMAPAHAKKRKYLMEKRIAALKEFSETTPLNRVERGEGKTGIITSGISYNHAKEVFGDGASYLKLGFTWPLPEKKIRDFAASVDTLYVIEENEPYIEDFVKALGVACTGREKLPWVDELTPEVIRRAFFPGEAETGGYAIDANIPPRPPVLCAGCTHRGFFYEVGKYKDIVVTGDIGCYTLGMVPPLSVTDSVICMGASVSAGVGFRKAVERAGRNEKVFAVIGDSTFFHSGITGLIDAIVNKAPIVVNILDNRITAMTGHQENPGTGRTLMGEPTHQVDLKALCMACGVKEENIRLIDPYDLTATKEAIKAGHDASEPFVIITTSPCALIKEVIKKRANMKCAVDEEKCVKCKLCLKAGCPALNFRGGRVYIDRASCNGCTVCMQICPKKAISREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJS4</accession>
    <name>A0A010ZJS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anaerobic dehydrogenase, typically selenocysteine-containing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_4_0_0"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="633" mass="69359" checksum="F1F102ADAD154529" modified="2014-06-11" version="1">MERDSITDGWKTTACPYDCPGTCSMLARVRDGKVELRANPANRRSRFLCAKGLRFAKRIEDPRRLLHPRRRRGSDWVDISWDEALYLWAEKISGAVKRYGPLSVMSFASAGSMTFSKQLIPAFYGALGGFTATKGSLCSSIGSAGLKESACGFGVPYVPPEDISTAGGALLWGRNSSHTQPQLTPCLEALRRGGGETACVEVRLSATAARCDRFWRIAPGGDWALAAWLCRRLVEEEKDSSGWRARAVNPGAFLNTLAGMDKERLLIQAGLSEDAAEEIYRWLLAHSPATHIPAYGAQRYLHGDMQFRWIFALAVLCGGFSNARAGLSFSKDEGAVFPEGLFEASSNVRRFGVTTWPAELMRAEPPVRVLNIYCANPAQQSPDTRLVEAAIGSVDFKVCSEVFMTRTAELCDLVLPASIFLEEEDWIGGYGHSYVSHNERVAAPRGECRSDWEAYGALARRLGLDLDMEALFSRMNMAVAADKRLREVSKNLYLWDEPCYWRLPASRALLPEAAPRPLKIPAGCLRLVTVHSDLYINGQNVDAPAKCLEAVINLPENFCLARGIAEGDRLNVASVNGAEIIMRAALDRSLAADTAWAMQGLPCLNALTAAQEAPGRGAPYAECFVKIEKLSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJS9</accession>
    <name>A0A010ZJS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="5" type="ORF">Cloev_1068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711167.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1136"/>
    <dbReference type="HOGENOM" id="CLU_074878_3_0_0"/>
    <dbReference type="OrthoDB" id="1280396at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006273">
        <property type="entry name" value="Orotate_PRibTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01367">
        <property type="entry name" value="pyrE_Therm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="121"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="199" mass="21823" checksum="89D1D2FACE708AA6" modified="2014-06-11" version="1">MSCSCEKNEISKKILEMMKESGAHLQGHFKLTSGLHSDNYMQCALMLRYPKFAACAGEELAKLLAPAKPDFILSPALGGLIIGHEVARALGVPFIFTERVDGEMRLKRFPHPGKLRFALVEDVCTTGKSSREAARILAAEGAEWVASGCIIDRRSPDCLPDWDLKSLVKVCFATYSAEECPLCKEGLPLVKPGSRPDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJZ7</accession>
    <name>A0A010ZJZ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carbon monoxide dehydrogenase</fullName>
            <ecNumber evidence="6">1.2.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_1145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>CO + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:21040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.2.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.4" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442460.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1218"/>
    <dbReference type="HOGENOM" id="CLU_030631_0_0_0"/>
    <dbReference type="OrthoDB" id="136177at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018492">
        <property type="term" value="F:carbon-monoxide dehydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043885">
        <property type="term" value="F:carbon-monoxide dehydrogenase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016101">
        <property type="entry name" value="CO_DH_a-bundle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010047">
        <property type="entry name" value="CODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004137">
        <property type="entry name" value="HCP/CODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016099">
        <property type="entry name" value="Prismane-like_a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011254">
        <property type="entry name" value="Prismane-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109">
        <property type="entry name" value="PTHR30109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03063">
        <property type="entry name" value="Prismane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005023">
        <property type="entry name" value="CODH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56821">
        <property type="entry name" value="SSF56821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01702">
        <property type="entry name" value="CO_DH_cata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0533">Nickel</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>[Ni-4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:47739"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>[Ni-4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:47739"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>[Ni-4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:47739"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>[Ni-4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:47739"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>[Ni-4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:47739"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>[Ni-4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:47739"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005023-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="627" mass="66141" checksum="B0746F6B43C734D1" modified="2014-06-11" version="1">MNQCFGCSTCKSADKPLEAFIRSLPLETSHHRVEGQSVKCGFGLQGVCCRLCSNGPCRVTPKAPKGICGATADVIVSRNFLRAVAAGSGCYIHIVENTALNLKNTALAGGAIKGEKALDRLCGLFGVTAADKYDKALAVAEMVLADLYKPEYEKMALVNKLAYAPRRANWEKLGILPGGANAEIVKGVVKCSTNLNSDPVDMLLTCLKLGISTGLYGLTLTNLLNDVMLGEPEIRLAPVGLGVIDPDYINIMITGHQHSCFSYLQDRLTDPEVTAKAAAVGAKGFRLVGCTCVGQDLQLRGAHYEEVFVGHAGNNYTSEAVLATGAIDAVLSEFNCTLPGIEPICDMLNIKQICLDDVAKKSNAEYMPFVFESRAPDSDRIIDAVIASYKARRGEVALNLQPEHGNSDTLTGVSEVSLKDFLGGSWKPLIDLIVSGDIKGVAGVVGCSNLTFGGHDVLTVELTKELIKRDIIVLSAGCSSGGLENCGLMSPEAAELAGPKLRAICKKLGIPPVLNFGPCLAIGRLEIVATELAAEIGIDLPQMPLVLSAPQWLEEQALADGAFGLALGLPLHLGEAPFITGSKLVVDVLTEKMKSLTGGQVIVDPDASSAADKLEGIILEKRAALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKZ0</accession>
    <name>A0A010ZKZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter membrane protein 2, PhoT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441206.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.26"/>
    <dbReference type="HOGENOM" id="CLU_033621_2_2_0"/>
    <dbReference type="OrthoDB" id="1763210at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="67"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="292" mass="30889" checksum="133E8D484780BF7D" modified="2014-06-11" version="1">MKGRLLFCRMIAGAGALYVAGACGALIFFLADKGLPVLGTRLFFGDTPPLEAMMGLRPVWEGIWPAFAGTFCLVLLTMLMAAVPGIGCGIYLARFARGRTKETLSLAINLLASVPSIVMGLFGFVLILALRHTLAPGATTSISLAAFCLALLVMPALVVTTRSSIESLPPMLELTGASLGFSENQILRRLLVPAAARGILGGMILSMGRAAEDTAVIMLTGVVVNSGLPAGLAAKFEALPFLIYYTAAQYADESELLRGFGASLVLLLLSALLMGVAWLCQRGMERRWKGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKZ8</accession>
    <name>A0A010ZKZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441217.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1097116_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="108"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="253" mass="27650" checksum="59B11CBAB15F69CF" modified="2014-06-11" version="1">MNRIEAFDENFFSFAAMLGSAPGGSLLRFAAPSLAAASGQPYAGENYAIFGIGAGNEDVTAALSFFSERRAEFVAPWLPQTPYGLAQIFEERGLLRRRIYTSMYLPAESMRAGEPPKDVSRITEGEARRWGEAAWYAFGGDDAADTDSYRGYGAYLAAHESNMAFALEAGGRYLSTALIHETENTVGLYYFATLPEHRRRGLALRLMDGLTAALAHKGKPLVLLATEAGLPFYINYGFKVIDKVPICSLTEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL85</accession>
    <name>A0A010ZL85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminoacyl-histidine dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484769.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.146"/>
    <dbReference type="HOGENOM" id="CLU_028526_0_0_0"/>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001160">
        <property type="entry name" value="Peptidase_M20C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43501">
        <property type="entry name" value="PTHR43501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016599">
        <property type="entry name" value="Xaa-His_dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00934">
        <property type="entry name" value="XHISDIPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01893">
        <property type="entry name" value="aa-his-dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="486" mass="52603" checksum="8268CFFE620AF5F7" modified="2014-06-11" version="1">MLSDKMKLLEDRTICHFTRLCGIPHGSFNEKKISDYLCEWARGLGLKAAQDEHFNVVIRKEASPGNEAAGAVILQAHMDMVCEKSPSYKHDFKKDPIPYQIDGDMISTGGKTTLGADDGIGVALIMAILESDGFAHPRIEAVFTTAEEEDLSGALSIDGSLFTARRMINIDHAADNEVVLGSCGGMAAELALPVERIPLDGGHVCRTIGLSGLPGGHSGENIHCGNGNAIVLIGRVLRRCEPLGVLISDISGGNFRTAIPREASVTAAVPRENTEAFDTALAEMEMAFKEEYLAAAPELRLSVTEATASQALSAACTERLIRALCLSPDGISAMSDRMEHVVESSDNLGELHLEEDVCRIICEIRAAYPSTAAYIADKIAMLSELLGARFRTFGRYPGWSYDPGSKMKEISNRVYAREFGEAQKNVVLHAGLECGCFYAVIPGLDAISVGPNMWNLHSPSERMSLSSVNKMARFLVKLLEELALER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLN2</accession>
    <name>A0A010ZLN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_13_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001431316" evidence="2">
        <location>
            <begin position="24"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="496" mass="53783" checksum="F93F656E6202C3ED" modified="2014-06-11" version="1">MMKKLTICTISALIMLTAGTAFAAKAEPQPSSRDIQLKNGEWTALAQIYPVPSVSSDVSQALTPERLASWWNVFNDPMMTELVLASLKGNRDLAAARAKVTEARATLGVSQASLLPWLDSTNFWSNGRTPVQAGGSGNSTNLYKLGIDASWEIDIFGGQRASVRAQRATLEAQYAALYSAWTSLASEVAMNYISLRTLQERLAIARYNLSLQQNTVDIQQSKVDSGLSDSLALKQAQYTMEQTKAGIPSIESSIEQTMNALAILVGEVPGTLAEKLAAKQPIPKISDTRFLGIPANAIRQRPDIRQAERLLVAQLARKKSAQADLWPKFYLTGSIGTEAGNWGSLFGGPAKLYSFMPQISWPIFHAGAIRNNIKAQGAIAEQLLASYEQTVLSAVGEVRDSLSANVKEYERSESLRRGVEAAQAALDVANDKYANGLVDFTNVDQRPALADVALGRVRHQPGTDIGQRRGALQSPRRRLPADGRGRTGPRRSGEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLP5</accession>
    <name>A0A010ZLP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1882133_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="135" mass="15058" checksum="130784CE728C22FD" modified="2014-06-11" version="1">MAKSFAELLREYRGDRSQAKVSEILDISATYYSELERGKKEPSYRILSQVVERSGKGLAFWLGGEGRSAPGEAPRLSSDGIADEERRYLTVPEITMMLGRVWHGIDNLPPLSVADRGIIADMLEACLRSLNKADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLQ1</accession>
    <name>A0A010ZLQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative oxidoreductase of aldo/keto reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441456.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.310"/>
    <dbReference type="HOGENOM" id="CLU_023205_3_2_0"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="335"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="377" mass="42958" checksum="39593FCC9E0CC142" modified="2014-06-11" version="1">MKKLGFGFMRLPMTDKDDPKSIDKEMLKKMVDIFLERGFTYFDTAYMYHDHASEAALREVLTERHPRGAFTVATKLPLMFLEIEGDQERIFDEQLEKCGVGYFDYYLLHNVNVHTYEKMKEFDSFGFIAKMKERGLIKHIGFSYHDDAELLDRVLTEHPEAEFVQLQLNYLDWDNESIQSRRCYETARRHGKPVVVMEPVKGGALAEVPGSVKELFRKYAPEMSAASWAVRFAASLDGVMVVLSGMSDMEQLLDNVGYMEDFKPLSAEEKEILDGAKKIISDANAIQCTACRYCVEGCPMGIPIPEYFALYNAEKQSNAAVFSISTQGVYYANITKTRRKASECVECGQCERACPQHIKIVECLKKVAETFETEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM00</accession>
    <name>A0A010ZM00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709035.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.389"/>
    <dbReference type="HOGENOM" id="CLU_079569_1_2_0"/>
    <dbReference type="OrthoDB" id="1945085at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="194" mass="21562" checksum="AD6069398A9CA966" modified="2014-06-11" version="1">MNFAAFFSYVILTAITPGPNNIMSMSNASRYGFRRSLPFNFGVFAGFLVVMSLSALFSSLLYDVIPSVKPLMLYVGAAYILWLAWTVWRDAPHEKGGRAVTNTFLSGMALQFVNVKVILYCITTMSSFILPHYHGLPVIAAFIIFLAFVGFACTLCWALFGALFELLFKKYSRPVNAVMALLLVYCAVSMLIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM30</accession>
    <name>A0A010ZM30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441584.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_363982_0_0_0"/>
    <dbReference type="OrthoDB" id="633672at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="807" mass="84385" checksum="F373ECD29A31D82F" modified="2014-06-11" version="1">MNKSFKKLGRNLALAAAAIFVVILFAGSMIGASDSWTPDTSWYDNYKNERGSAENPFLISSPEELAGLAKITNVAFGQWGVTKVSLKDKHILLTRDINLEDKEWAPIGWYLSYTEKSSWGSVTKEYAGFDGNFNGGGHTISGLKIETCENVPLYSSKQTEAAGLFGYISIDGKVRNLVVKGKVNASECEGVGGIAGWADGLIENCVTDVEVRATSSKRGYAGGIAGLNGGPQGDDMTSGNPYAIIRNNVVLGSVFSTPASFAYAGGIVGFSHWYKGEVLNNVALSPSIVSGMDAGGIFGGFNSFVTADNVSAAQKLAGAPGYVGGVVGAFGWGYQNCYWLSVNRDQPVGGITDPAKLPVTAVAMDTDNLKTIKSGETRDIHITAYPLTADASSLKYTWSVDKSKLEVIKGAGTPTLTVKAKDGAGTEDLFAVISADVYGLLGHTESQSGGSVVYISNFETTASVQGVLKITQGAIPVEGITAYGSNTAWKEGETRVLGASVRPSDADARDVVWTLSAVSGAASSEDVIMEDAGNGNLSILLRSGHEKDYAYTFTAATADGKFSDSITVVGDPVTDVEISGFIPTGDAVPNYIDAVKPVGATSAVIEDIAAAVGVDVSVFRVGLNGVLYLNSETVNAAVKDAEDRDNLKVTAIIPLPLFSVKVSAAGKIAAAGMIISGDRLMAETPQKVALVKTRPDGTGEFFTYAEDQDAIGNKRFTLQTMDDKTMAPTDKIDPAQTYKLVLYIQDNGGFDIDPADCSIIDPVAIVKLAEETPAPSGSSSGGCNAGVAGIMLLAVIPLLTRAAKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM43</accession>
    <name>A0A010ZM43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2Fe-2S cluster-containing protein, BFD-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0409</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085555_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="261" mass="28674" checksum="7A8A3A5E8054BD76" modified="2014-06-11" version="1">MADKEKLFNSGVLTDHREGALLPPKDKWEGKKGGFVVIECPKRIPCNPCATSCPTGAVLPFEDINDTPKINYDKCTGCGICVSRCPGLACFVIDLTYAPGKAVIKLPYELLPIPEKGQRVACLDRTGEAVAEGEVLAVTEPSKDKTYVVSVVIPAELADDIRAIKVPETPECHVICRCEEVEIETIREWIARGYDTFDELKRELRVGMGPCQGRGCRDIIMREIAKATGKTFEEIGPGTMRPPVKPIKLSLLAKDFEDNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM73</accession>
    <name>A0A010ZM73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage recombination protein Bet</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484830.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.497"/>
    <dbReference type="HOGENOM" id="CLU_815919_0_0_0"/>
    <dbReference type="OrthoDB" id="960894at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010183">
        <property type="entry name" value="Phage_lambda_Bet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018330">
        <property type="entry name" value="RecT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03837">
        <property type="entry name" value="RecT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01913">
        <property type="entry name" value="bet_lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="310" mass="34584" checksum="331D953FA3C4BF8E" modified="2014-06-11" version="1">MAQEAVTAAEAPRFRQLSDKDRDLLRKGLCAKCTADEFELFAETCNKTGLDPFMRQIYPVFRPDRKQNRDVMQIQVSIDGMRLVAERSGHYAGQVGPFWCGKDGVWKDVWLSDKEFPVAAKVGVMRHDFNEVLWAAARFQSYVQTTYERRPNQMWNKFPDVMIAKCAEALALRKAFPMELSGLYSTEEMSQADNAEPSTGKVNVSPNTAPKAETPAPAKPEPAAQEAPQPAEDRKSAPPQEADDHTVLSRTLMNLLVSEQGLGFKKSEIAPFIVRVVGRSNFKALGELSLEELSRCVEVARDELSARSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMN1</accession>
    <name>A0A010ZMN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_344817_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="835"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="124"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="857" mass="93986" checksum="F454B0F1C6FFF0ED" modified="2014-06-11" version="1">MQSKRFLKNVQTAIIVAFVICSLSFIAIASNSKGKPASESEVGGSWSVDMSKLENLWFADQNWDGKSLKEYSSKVKAHFADPDASEFGDHPDFTAEMRANENDPEGTVKILTNAQMNSYLESLPKDNMTIRYIGDYPSGMRMPLLVFSSPKLDDPSGEKLRALNKPIFYLRAQVHGNEVASTAGAIMLAQRLCQKHSDVAGLLDKISIVILPRMNADGTKIHQRGTSIISGDTWETGLPDFFESSGPGGGMSQYGGGLMGGYDQNRDSVWLGAPAARAHARVLAEYAPEFCLDAHEYECNGYYGLPSKITSGDSFVYETDPDNGGRLVLKDDGGTLCYYKEQITTQWGNHLLIPEALRTSSEVIQQKIANGLQKPSNPSGSFFWAPYVDTRGYGLAIGEDGKSTGGLVSLNSIPAGEQRDAVKKWSDANGNVPELGAYQESIEGGFDPSIARNSMGLTGAISFLVESRSAGGRWEFARRTMGQYLTVLYYLKAITDDLDNYSAEVKEARAEILAGGKAENIGKEKYMMTIRQDYDTVDYSDVVTQGVYYHDGSSEDIFGLRKNSRFGMKPTFECLRPYAYIIDGSYSMADTIAFRMSNLGVKFERLTAPVSLDVEAYTITNMGKLSSFGASCKIEGVNKAEKVVSFPTGSYVVYMEQPMANYAAVLLEPMSMRSWSGKDVKNNETRLGKEAPFYRYMKTEKIADTESVEVVTLDFTDFFVYDIIPFSVAETENVRAKTMDSVFGETVSVYGLAPKSDIKAYLPSDGDTRNWFVYDATTKSYGQKNITFDEEMNRNYITIPAKDFIDAGDGYYTVNVAVTPAGTQPVSSSSSGCNAGAAHIMILIGVSVVLFVGKKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMW6</accession>
    <name>A0A010ZMW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_9_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="46"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="473" mass="51122" checksum="7ABC2632EE406BC7" modified="2014-06-11" version="1">MMEYGIITDEILAALAEIAGPAHVWTAEEKLEACSRDETTTLRAGERYLPDAVVAPASAQEVSEILKLANRHVIPVTPRGGGTGLSGGALPVCGGIVISDERLNRIIEIDAENLVAVTEPGVITSEINAAAAEKGLAYTGYPMSVLSCHIGGNIAENAGGGNAVKYGVTMRYVLGLEVVLPTGEILTLGGKLMKDVSGYSLKELFVGSEGTLGYVTKIILRLQPLMKNRAALLALFSDTETAIKAVPKMMAHGGIVPSSIEYIDAYCYRKACGFLNEELPMSGVEAVLLVEVDGSNQESLDMDIERAGEILSAEGAAEIYVADTRSTRERIWSVRRSIDEALRLTDPVQADEDIVVPISRIPEVARGLREIEKKYGVPIANFGHAGDGNLHPTILKPAEMTLPEWERVETEIEWDIFRLTDSLGGVISGEHGIGSKRKHYFMELCPPQNLELMRKIKLALDPNNIMNPGKIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN34</accession>
    <name>A0A010ZN34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethanolamine utilization protein EutJ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442025.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.827"/>
    <dbReference type="HOGENOM" id="CLU_088869_0_0_0"/>
    <dbReference type="OrthoDB" id="1044637at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013366">
        <property type="entry name" value="EutJ"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02529">
        <property type="entry name" value="EutJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="272" mass="29307" checksum="16AE9316B35DEA5C" modified="2014-06-11" version="1">MMDLKRVNACMAKVAASEKRCFKPAGKKLKAGLDLGTAYIVIVVLDENDDPVACEKEGASVLRDGVVVDYQGALAVVRRLKGELERRLGTELGKCAIAMPAGTESSARTHRYIAEGAGFEVTEILDEPTAANSVYKIENGVVVDIGGGTTGLAIFKDGVVEKIYDEPTGGTHLSLVLSGNYRIPFDQAEVIKQDYRKHAEIFPIVRPVIEKMATIVARNIDTDETDTIYLCGGTSCLTGIEEVFEKVTGVHTVKPENPFLVTPTGIAMNCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNI0</accession>
    <name>A0A010ZNI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484884.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023978_4_1_0"/>
    <dbReference type="OrthoDB" id="724641at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="443" mass="51114" checksum="ED9F2669006FC465" modified="2014-06-11" version="1">MYEYLLAFLKPIIEPFMSGDAWPLIMRFMPFIIFYELPYALLIYAGVMKYIWERGGEGPRRPYFPPVSCVITCYSEGRGVQGTIRSLTEQVYPGRIQMIAMIDGAARNKDTYESALEMRGYVRSFAARSLEVVPKWQRGGRVSNINTGLNYVNGEILFILDGDTSFDNDMVERAVRHFEDPSVAAVSGCLRVRNADSSLVASLQAVEYFISIQTAKTGLSEFNLVNNVSGAFGIFRRSVVELVRGWDAGTAEDLDMTLRIKQYFGRYGGKFRIVFDPEAMGHTDVPDTLLGYFRQRIRWDGDLPFIYFKKHWRAFSARLLGWPNFIMAVLNGLYSQIVLPFIIFTYTLWLFWEYPLSYVLSLLFVVYLFYFLLLTAMYVTSLIFISERKKDDLSRLPLLPLFPLFIFSSRINSLVATIYELVFKSHKDSSMAPWWVTRKSKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNI7</accession>
    <name>A0A010ZNI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease component of ribose/xylose/arabinose/galactoside ABC-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0906</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710909.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.969"/>
    <dbReference type="HOGENOM" id="CLU_042763_0_0_0"/>
    <dbReference type="OrthoDB" id="1155165at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="348" mass="37457" checksum="F54E5447DD3ADF57" modified="2014-06-11" version="1">MKNKLQEFIENAGWPRVIIALFLCALFVAAPFVGVRIDASLSDTLVRVGMNGILVLAMVPMVQSGCGLNFGLPLGIIAGLLGAVTSIQIGIRGSVGFLLAAAIAIPIAVVLGWLYGQLLNRVKGDEMMIATYVGFSSVALMCIAWLLLPYTSPTMIWGYGGSGLRTTISVEGYWLNALSKYVNIQIGEFFYVPVGMFLFFAFVAFLVWAFFRTKIGTAVTAVGSNPEFARASGIDVDRMRTISVILSTVLGAVGILVYEQSFGFIQLYMGPFYMAFPAVAAILLGGASVNKATMVNVVVGTFLFQGILTMTPSVINSVMQTDMSEVIRIIVSNGMILYALTRKVTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNP5</accession>
    <name>A0A010ZNP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">Cloev_0987</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710995.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1057"/>
    <dbReference type="HOGENOM" id="CLU_158491_5_2_0"/>
    <dbReference type="OrthoDB" id="2063644at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="71" mass="8225" checksum="835583ACD56D4485" modified="2014-06-11" version="1">MDPKELRDLSVSELKDKHKQYKEELFNLRFQNAIGQLSNSGRIKDVKKTIARILTVITEKEMGIDHSGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNT3</accession>
    <name>A0A010ZNT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-dependent protein deacetylase, SIR2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_1028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711062.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1098"/>
    <dbReference type="HOGENOM" id="CLU_023643_3_0_0"/>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="244" mass="26620" checksum="3AE37634102D4070" modified="2014-06-11" version="1">MSVEEDAKRLARLVKEGGVTIFSGAGLSTESGLQDFRSRDGIWAHADPTRLASVGALEDNYEEFLEFYKARLYVPEEIQPNIGHKIIAKWEKEGYVDGVITQNVDRLHQKAGSVNVWELHGSLEPVRCHSCGGEGSTADFLAGKPCARCGGRLRPSVVLFGEMLPQRPLEAADELSDGCRTFIVLGSSLVVSPANYFPRQAKSRGARLAIVNRDPTPLDGIADIVVHEGIGAFLTEVEKDMQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNX4</accession>
    <name>A0A010ZNX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="6">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="6">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">folD</name>
        <name evidence="9" type="ORF">Cloev_1087</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="6"/>
    <dbReference type="EC" id="3.5.4.9" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484909.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1156"/>
    <dbReference type="HOGENOM" id="CLU_034045_2_1_0"/>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="7">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="8">
        <location>
            <begin position="135"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="295" mass="30778" checksum="5E9AA9621D0EDD3E" modified="2014-06-11" version="1">MSIVLKGAPVANALTEVLKERAKKLKEKGVTPTLAILRVGEREDDLAYERGAKSRCGKVGVDVRCFVLPGGCSRNELLDAVRTINEDDSIHGCLMFRPLPVKGDELAACALLSPEKDVDCITGGSLESVFIGAGTGFPPCTAQACIEMLDYYGYSLQGKRVTVIGRSLVIGKPVSMMLQARHATVTMCHTKTADIAAACRNAEILIAAAGKAGVVGADYTNREQVIIDVGINVDAEGKLCGDVLFDAVEPLVAAITPVPGGVGTVTSAVLAKHVVEAAEKTLALVPDLAAACCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNZ6</accession>
    <name>A0A010ZNZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinose efflux permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711235.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040537_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="397" mass="42387" checksum="F5B78D8E4FCDA437" modified="2014-06-11" version="1">MDSTAACNDCRAISKRNKRTLFGVIFLHGLNDMHSTALPTIIPMLAQSISLTMSQAGLLNALFGITNIFGQPVFGFFADRLRRPWFAVWGPLLSVTGAALLPLSPSYGTAFIFVGMMSVGTALFHPQGTGRCGATAGENALAFYLSLFQASGSFGSAIGPIYVVFMISMLGKPGFPLVIIPVAACVCLSLWRRMGRRADEAAREAGERPQFLRNLRYLISRVGWIVSITSIRDAVFQSIKIFLPMLLITRGSTIAMGGMVLFAATLSATFAGIVGGKLADMIGDEKVLFGALAASPLFLIIGLHASNLFCLLSLMVGFAFLQASTPVTTAMAQRRCPDSRSMVSSLSNGVSWGIANLFVTPVGIIADIAGLQATLNAVAFLPWLVTLLYIGKKLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7A8</accession>
    <name>A0A011A7A8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484739.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_0"/>
    <dbReference type="OrthoDB" id="1497607at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="185" mass="20767" checksum="CE8B30535460B53C" modified="2014-06-11" version="1">MIETERLIMREITEADFEAASRILGDAGVMYAWEHGFSEEEVRRWIGECIRRYKDDGFSYLAAVEKTSGEIIGFIGPLVETIEGCRHFGVAYILMKERWGMGYATEGARASLACAFERLGAERVIAVIRPENSASRGVAERLGMEIEGRFIRHYRGKEMPHLIYAISKEKWKAASEIAPPSAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7J8</accession>
    <name>A0A011A7J8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.145"/>
    <dbReference type="HOGENOM" id="CLU_094919_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="217" mass="25357" checksum="60ABB972774F2C9C" modified="2014-06-11" version="1">MDIQKLSIKKRRVMIYFIEAARQLMSSDGIQALSIRGIAEIAGYNSATLYNYFEDLQHLTLFASMSYLRDYVSALSGKLKAPMSSLQRYRVIYETFDHFAFRSPEIFYNMFFGSQSSKLPEVTVQYYTLFPDELKEHTPSVRKMLTQGNMYLRDEPIVEELVKDGFVKRENAPYLSAIVPRLNQTYLHELANGERIDPEEQHRRFIAVFDYLLETAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7T1</accession>
    <name>A0A011A7T1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase, histidine kinase/DNA gyrase B/HSP90-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.234"/>
    <dbReference type="HOGENOM" id="CLU_000445_114_0_0"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="159"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="351" mass="39153" checksum="FD1740EB65E1F40F" modified="2014-06-11" version="1">MKNDAILNAIFTSIYAPVAVYHVTGGGDEPVDLIYDRVNRAYLELNDFAQEEIIGRRYTEVCRDETEEPWMKCMLKVAATGTADCCEGMCVRRTGYYVSLLAFSPVAGRVVAIVRDLSEWHKSRLNLIEKQELLQKLTTRLTLAEERTRRDIANTLHDGVGFEMVTMLNSLRSLREKTEGRDAKELLADNISRMEKLIENTRSFTFEISPPLLYEAGLDATLEACCGHMFGTNGVKCDFRSEGTEIRIAEDTKVLLYQMAHEILVNVAKHAKARNVLVMTRWGAKKVQLFVRDDGVGFDQSGDNLPSTTSGMGLFSIRERMSAIGGQFNVISEPGAGTTVSLIAPIRPAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7X6</accession>
    <name>A0A011A7X6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisC</name>
        <name evidence="5" type="ORF">Cloev_0252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709417.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_3_0"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="30"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="359" mass="38967" checksum="992954CCB52250DE" modified="2014-06-11" version="1">MQETEELFRSMARPAIWGIEPYDASTIEEPKIRLSANENNEGLPPSVLAAMRRALAGGNRYPDSRNTALREKLAACFSLRPEQIMTSNGLDGLFTMLGRAFLAPGDEVICGECTFGVYADTALIAGASVKKIPLGEGYGQIPADFAAAVGPATKMLFFCNPNNPTGTLADAASLRKMLEDIPPRVAVILDEAYFDFTGEDGSESFKLLEEFPNLIICRTFSKLFALAGLRVGWAAAHPGLLDYLYRVREPYCVTSVAEAGAIAALDEKEHLGKTCAAVAAERGKLCAALRRCGVEYIPSRANFVLIFPRERYDGLAAAFAQKGIAVRGLSLRKERVMRISVGLPEENRQVEMALGEIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A855</accession>
    <name>A0A011A855_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta superfamily hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484808.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.343"/>
    <dbReference type="HOGENOM" id="CLU_048587_0_2_0"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010520">
        <property type="entry name" value="FrsA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06500">
        <property type="entry name" value="FrsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458584" evidence="1">
        <location>
            <begin position="32"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="371" mass="40635" checksum="AC42B22E81AA8357" modified="2014-06-11" version="1">MTIDLAQKIFLAAAIALISALALVSANAAFAADADPWFAPLPKQAPAPQYADHGADNFYKSDKVTAKDVSFKNQFDMKVAGRLFVPKSYKQGQKLPAIVVGHPMGAVKEQSAALYAQKMADRGFAALAVDLPFWGSSDGTPRNSVNPDLYSEAFMAAVDYLGTRDFVDRERIGGIGICGSGSFLISAAKIDPRIKAVATVSMYDMGQAMRNALNKSQTVEQRKAYIAAAAQQRYAEFQGGKRRLLGGTTHTLDAQTDPIQQEFYDFYRTTRGAAAGKGQDLNTTTHPTFASAVKFMNFYPFEDIETISPRPMLFITGDQAHSKEFSEDAYKRSAEPKELHYVKGAGHVDLYDKTDLIPFDKLNDFFTANLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A883</accession>
    <name>A0A011A883_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441525.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.372"/>
    <dbReference type="HOGENOM" id="CLU_157896_2_1_0"/>
    <dbReference type="OrthoDB" id="2078961at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="102" mass="11248" checksum="228A77EBB2F35F0A" modified="2014-06-11" version="1">MPRNVYLYLLIMAAVTYLIRVLPLTVIRCEIKNRRVRAFLYYVPYVTLAVMTFPAIIDATGSTLTAVAALMAAAALSWFGGSLLQVSVLSCAVVFVLDKFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8R2</accession>
    <name>A0A011A8R2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rph</name>
        <name evidence="7" type="ORF">Cloev_0525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.562"/>
    <dbReference type="HOGENOM" id="CLU_050858_0_0_0"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="15"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="163"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="254" mass="27817" checksum="3048B714CC2FF1B6" modified="2014-06-11" version="1">MTELIRIDGRGVETLRPITFERAVSRYAEGSALVRWGNTHVLCTASVDEKVPPFMRASGSGWITAEYAMLPRATHQRSPRDISRGKQNARGSEIQRLIGRSLRAAVDMPKLGERTITIDCDVLQADGGTRTASITAGFIALFDALRWLRANGRIVSIPLKNQIAAVSVGKVAGAPMLDLCYEEDSTAEVDANLVMTGAGDFIELQGTGEGGSFSYTELAQIIDLGWSGISEIQQRQREILALSEEERELFEKCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A933</accession>
    <name>A0A011A933_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441905.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773153_0_0_0"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="23"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="372" mass="40303" checksum="8165C7F2E166D27D" modified="2014-06-11" version="1">MTNIPTDIKSFTELKPWWRTPVPTEIVLSGRGVDELLSKLKERGRKPFFVVDGALKEQPRFAAIFAQRDLFVFDATSSEPRTGDVDSLRARIKAMDREPDTLVGVGGGATMDLSKAVAICLANDEPAQHYQGYGLAMNKGADIWVLPALNGTGAEITPIAVLRGPEKKLGINNPYTESAVAVIDPQLSADAPHFNRFFTMMDCYFHHYEIMMSKTSAPEAIEDAKDGLALSREVLSHDLSGYSLDLAIKSAMASVLGGSSTIGGRVGAAHAISYGLSNSAPHLPHSVAVAISMSVLEDVYPEGYGDTRRFLEINGLAMPKAADYGIGEKDAAKMTKTALGMEKLWHSCFGDGWKGIATEEYIEKIYARIIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A963</accession>
    <name>A0A011A963_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441948.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080344_4_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459381" evidence="1">
        <location>
            <begin position="25"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="243" mass="24964" checksum="7F148F5E9120BD3F" modified="2014-06-11" version="1">MKHSGKLMAALAAAGLMVLFGAGAALCAEQTRDSISVTGYASQESEPDMAVVSLSLTEYGKTAADTRAALASRIDKLNKYIASLRIAAKDVKTSGYELAPNYEMVREKRVQKGYAASAVFTVTVRNMAGLGAVIDGSAEKCSAMINDVSFGLQNREEIERGLLAAAVEDAKGRAAAVASAGGRRLGALISASIGSAGAAPQPRMMKGFAGDAMNAAAAPATQLSPGVIKVAVSMSLVFELANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A984</accession>
    <name>A0A011A984_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_19_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="18521" checksum="315433D122E500A7" modified="2014-06-11" version="1">MEIRPVMLEDAEAIASIRRQNGVCEGVLALSSERINTTVDFLNSLTGRDRGYVAVENGEVVGFSVMMANREPCRSHSAFIAVMVDTDFQQMGIGHRLLKHLVDRADNELMLHRLELLVLTENERAIKLYKDLGFMVEATKKHAAVVKGAFVSEYLMGRLRGEGAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9J3</accession>
    <name>A0A011A9J3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710765.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.876"/>
    <dbReference type="HOGENOM" id="CLU_091233_1_0_0"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="69"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="164" mass="18863" checksum="3B27A8E764FC5C1C" modified="2014-06-11" version="1">MDSRHREEILRLLEQNARYTAKDIAVMLGMDVIEVKNEIEIMERERTICGYHALVDWDKTDDDKISALIELKVTPQRGEGFDRIAEKIYQYPEVESLYLMSGGYDFSVILKKATMKEIANFVSSRLAVIEEVQSTATHIVLVRYKDHGILLAAPKKDMRMVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9U0</accession>
    <name>A0A011A9U0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CCG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445332.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.963"/>
    <dbReference type="HOGENOM" id="CLU_1270450_0_0_0"/>
    <dbReference type="OrthoDB" id="1951488at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="101"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="223" mass="24986" checksum="5A127E37C71A8104" modified="2014-06-11" version="1">MSLKDAANLYFNPGCALSIYRPENVKTIFDYLLKNFPEIEMHDICCRHDPKLPGGSVIINVCAGCGKRFGSLYDGVSTISLWEVIRELDNFPFPDYKGMEVSIHDPCPVRNEPGVHEAVRAILKKMKIRIVEAENIGTNSVCCGDSLYPSCDKEKILAAMKRRADSMPCENVAVYCVSCVKAMHIGGKVPRHLVDLLLGKATDPQECDIERWHNKLDAYIQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9U9</accession>
    <name>A0A011A9U9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710916.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.974"/>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_0"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="215" mass="24690" checksum="A99596B8BE6F0B0B" modified="2014-06-11" version="1">MEEKSLSAQVYEKIKAGIISLKYPPGSVLKERELSESLGVSRTPVREAIQRLSQESWLVPGEGKRMQVRPVTIADVHEIIQIRNLVEYAALDDLLKNGEPRVAAGQLDSILNEMKSATEVYTLTTLDLKFHYLVVESMKNERLLRFWSTVQDEVLRMGLLMLKRKDRWGEVISEHERLVEMLWNKDAEKTRLAMKEHLENSYAALIRDPAGCLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9W6</accession>
    <name>A0A011A9W6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction-modification system methylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0938</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1006"/>
    <dbReference type="HOGENOM" id="CLU_896549_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="159"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="320" mass="35648" checksum="B3237E8E991135E5" modified="2014-06-11" version="1">MKVIDLFSVEYGVNLELLNCEGTTADDINGVNFVSRTASNNGVVAVVKKIDGVIPQKAGTLSCAGGGSVLETFVQTKPYYSGRDLYVLTPKKSMTIQEKLFYCMCIKANAYRYNYGRQANKTLKDIQLPDIIPSWVNSTPVNPVTTKNTTENALPLDKSTWEEFPITRLFNTARGKMGSVTDCESGDIPLVTAYTQNNGVSNYISCESEYVNNGNCLTVANTGQGSVFRTFYQPSKFVPSNNVTCLTAKGFTMNKYIGLFITTLCWLEIPRYSYGRIVNNTRLEQTVLKLPVKKTDKRKGVPDWSYMENYIKSLPYGDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA96</accession>
    <name>A0A011AA96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711199.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147162_6_3_0"/>
    <dbReference type="OrthoDB" id="2036309at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="105" mass="12127" checksum="7C8FE2BA2F4D8305" modified="2014-06-11" version="1">MKQYQIKITNKALEDMAEIYEYIADNLKVSDTAMKQYDRIADGIESLNEFPERYKLFAFQPECDLCLRQLPVGNYSAIYVVEGDCVTVLRVLYSSSDIITRLRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAB1</accession>
    <name>A0A011AAB1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="2" type="ORF">Cloev_1114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711233.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1187"/>
    <dbReference type="HOGENOM" id="CLU_077150_0_0_0"/>
    <dbReference type="OrthoDB" id="1025521at2"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="176"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="311" mass="34478" checksum="E2B661E0C366CF56" modified="2014-06-11" version="1">MLWNLNKVIISQNDGLPVDWRGMSPSGRVLVEIGFGNGEFLEFLAGSNPDALIVGVEVSQWCAAKGARRILAAGYENARVMHGDARFLLRHCFAPESVERVYMNFPCPWPKTRHASRRVTVPSFADLMKYLISPGGALELATDVDWYALETAEVFSGDPAFRADPVAVNPARPYVTKYERKWKAMGKDTWHLTIHKDVKLTEKPAGEDDWPMECEASTKKSVKEVIDSLKDCEGEGVGGKGHWVFRDAFLSDGGVGLMLVITADEEFEQHFYLKVIPNPRGVTIKVDSVGHPYRTPAMRAALLKALAAAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAC5</accession>
    <name>A0A011AAC5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Acyl carrier protein</fullName>
            <shortName evidence="7">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acpP</name>
        <name evidence="11" type="ORF">Cloev_1129</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A011AAC5"/>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1202"/>
    <dbReference type="HOGENOM" id="CLU_108696_5_3_0"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 7 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7 8">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="83" mass="9421" checksum="81338D17BD811F0A" modified="2014-06-11" version="1">MKMEEVQSKLKEIVMDRLNAEEDQIKPEASFVEDLGADSLDIVELIMGIEEEFDIEIPDEDAEKLTTVGEAMEYVKTKLAVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCG6</accession>
    <name>A0A010YCG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ysc84 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034444904.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015320_4_1_0"/>
    <dbReference type="OrthoDB" id="1808930at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84" evidence="1">
        <location>
            <begin position="96"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="223" mass="23061" checksum="697FAE5E80FC1A4D" modified="2014-06-11" version="1">MIIAVFTVIFVNEAYAAETPLYMKRIDMAADLVNKMALQADAAGMADTIRSAKGVAVFPDVAKAGFIIGAEEGQGIVLLRTENGGWSGPAFMGVSGASVGFQVGAESIGLVLVINNDNGLHAFTGGNSFKLGADVAVAAGPVGRQFGASTNAPLKASLYSYSMTEGLFAGISVSGSVINQNRDLNLAYWGKRMTAQQALAEPATDSRILPLVNALNGLTEKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCK7</accession>
    <name>A0A010YCK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type sulfate/molybdate transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0074</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709830.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="357" mass="40000" checksum="6C32FB43A5BB3B8F" modified="2014-06-11" version="1">MSATVNFKKQLGSFSLEVDFEAGNEVLALLGGSGCGKSMTLKCIAGIVTPDEGQIIVDGVTFFDSKKGINLKPQQRRTGLLFQNYALFPNMTTRQNIMTVFEHGAGRSANKEERYQEIARRFFITGLEDHYPSQLSGGQQQRVALARIMASDPAVIMLDEPLSALDSFLHWQLELKLSRILREYSGTTLYVSHNRDEVYRLCDRVCVINQGRSEPVKTVAEFFDAPPTLAAAILSGCKNFSRIDIIDSLRLRARDWNMTFACARPIPDGARYVGVRAHYLIPVPENERDENTIKAEILEVRDDVFTAIITVRPNETESESNFAVIRIELSKELAEKYHTGETIYLKVSPADVMPLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCT9</accession>
    <name>A0A010YCT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Citrate lyase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0158</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709253.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.169"/>
    <dbReference type="HOGENOM" id="CLU_044864_0_0_0"/>
    <dbReference type="OrthoDB" id="1107373at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="5">
        <location>
            <begin position="3"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="286" mass="31586" checksum="7AE9035D92086506" modified="2014-06-11" version="1">MRRTMLYLPGNNPNMLTRGYLFGSDGVVLDLEDAVAMVEKDTARILVSKYLKQGEFGSCYVSVRINGVDTEYWKDDLAAIVPNKRLDGIRVPKVEDAGTVKIIDEELSRLEEKNGLPVGKLTLHCLLETAHGIWNAYEIAKASPRIEAIIPGGEDLRADLKTNRSDDSTELEWARRMLVFAARAAGVEPLDTVFPRITDDEGLRKETEFIKQLGFSGKSIIHPNQIKIIHDIFTPTEAEIAKAQKIIAAAKEAAERGQGAVTVDGKMVDIPVVKRAEYTLVRAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD70</accession>
    <name>A0A010YD70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441443.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.296"/>
    <dbReference type="HOGENOM" id="CLU_069356_12_3_0"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013572">
        <property type="entry name" value="Tscrpt_reg_MAATS_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08361">
        <property type="entry name" value="TetR_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="205" mass="23970" checksum="39B096F50118CF2D" modified="2014-06-11" version="1">MRRTKEAALETRAKILESALDIFSEKNFSNASLTEIAANVGLTKGALYWHFRNKNDLLLRLFEEICRHGEDRVKNLFDAPDSSGKLRRYYKNYLARLLKDDRNKKIHKIMTKRDEWPEDIQQSVSQIIKDSMEREKLMVKNFVRKGQEEGRLRKDISAEALAVLISSIFHGLCVMQLSGMLPKEFPQYTDILFDAFEKELNIKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD77</accession>
    <name>A0A010YD77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708929.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.302"/>
    <dbReference type="HOGENOM" id="CLU_000022_59_8_0"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="3">
        <location>
            <begin position="31"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="713" mass="79526" checksum="92BA3D45AEB34A93" modified="2014-06-11" version="1">MRRLIVKLILRLFFRVKVKGWENWENAGEGVLIAPNYVSFIDPLILAAFLPEKVPFAIERRLTKKRFARFFLPIADTHILDADAPLTLKYFLSLLKNGGRCVIFPELQPTIIGNPMKVSQGVAMIADHTDAKILPIHIKGTERTPFSRIQHKRGVRFFSEVTITVFPVQNLNIPEGLTGSKRNAAAGRALERIMDEASLSARRKQKPFWDILLDARREFGGNVRIFSDAGAKPVTYNGFITRILLIEEALREQNLEGDNIGVLLPTSLGGVIAMYALQKMDKVPAMLNFSLGPRSLVNCCRSACVKTVVSSRKFIELGKLEALSNAIEEAGIRIFWLEDVAPLITTGKKLSAALRTPFLRSDPVTPGAAEKPAVILFTSGSEGAPKGVVLSYKNLNTNHAQMFTRVDFYRSDRVLNAMPIFHSFGLCGVFMPVSLGFFVYLYPSPLHYKTIATICYDERITLLFATDTFLAGYAKAASDNYDFATMRLLVQGGEKLKPSTQQTWFERFNTRITEGYGVTEAAPVVSNNYYAHHKTGTVGTIVAGLEYRLEPVDGVHDGGRLWLKGDNIMLGYLRISNPGVLEPPKDGWYDTGDIVHIDDEGYVTILGRAKRFAKIGGEMISLAAVEEAMFEIWPEDQHAVTMMHGANRETLTAVTTRADMKRDELRQRLSELGMAEIAIPKKLLYMETIPLLGNGKTSYVELDEMLKNMSSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD83</accession>
    <name>A0A010YD83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441455.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.308"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_4_0"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="389" mass="42194" checksum="2509EF7517A0D6B1" modified="2014-06-11" version="1">MSFTMYVPTKTLFGAGMLNKLHEQRMPGKKALIVISKGKSTKANGYLARVENELRLAGMTWALFDRVEPNPLRSTVMAGAAAARENGCDFIVALGGGSPMDASKGIAAMAVNDGDLWDYIHSGSGKGRPLANRPLPIVAITTTAGTGSETDPGGVITNEEMHEKSAILDENLFPVLAVVDPELMVSVPPKFTAYQGFDALFHSVEAYIAGTANLMSDMFALAAIENVSRYLARAVRDGGDIEAREHVAFGNYASGFVMCVGSCASEHSLEHAMSAYHQELPHGAGLIMISRAYYTHFIERHVCDERFIRMAKAMGMADASEPMDFIRVLTKLQEECGAAELKMSDYGIKPEDFETLAKNAIDTMGFLFQCDREPLSIEDCVAIYAASYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDA7</accession>
    <name>A0A010YDA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein, gamma-carboxymuconolactone decarboxylase subunit like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.331"/>
    <dbReference type="HOGENOM" id="CLU_070025_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="70"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="205"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="292" mass="32728" checksum="B0B9C65B9AE08604" modified="2014-06-11" version="1">MPQFKYFMISMAVLALVMAMTLLLERACSAEEMVPEWALKAQLRERSDFGRPKFEELFKGRDGARYGDEELVAVMDRFLYGDIFRRGTLTDKQRELITLAVLTTNRNLDDLKAHVKASLNIGVTPEEIKEAVYQCAPYIGFTKALEGAYAMNEAFREKKIKLPLASQATVTEKDRYAKGFVTQKSIFPAGLDGMYQSSPENRKHMAEYLASVCFGDFYTRGAIDVKMREILTLCVLSAQGGCESQVKSHVQANLNVGNDEDLMIEAITQCLPFIGFPRTLNALACVAEVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDC9</accession>
    <name>A0A010YDC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Fe-S center protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708990.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.349"/>
    <dbReference type="HOGENOM" id="CLU_046240_1_0_0"/>
    <dbReference type="OrthoDB" id="1000643at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458819" evidence="1">
        <location>
            <begin position="27"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="DUF362" evidence="2">
        <location>
            <begin position="60"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="316" mass="34438" checksum="A42A4F9475F84C29" modified="2014-06-11" version="1">MYDRFRKFIGIALALLVILSGGAAKAADENVSIVYFTKDISPAGLLKVYDKVNAGITGKVAIKLHTGEPKGPNLLPLPMIKALQAHIPNSNLAETNVYYSSPRQTTAGHRETIKTNGLDFCKVDIMDEFGAVMLPVRGGRHFKEMSMGKGIMDYDSMVVYTHFKGHTMGGFGGSMKNIAIGCADGKVGKAMIHAKEGQQWGQTQDAFMERMAESAKATVDHFGKHITFINVMKNMSVDCDCAGSSAAAPTAKDVGILGSTDLLAIDQATIDLVYKLPEAQQKDLRERIESRHGLRQLSYMEELGMGNRKYKLVSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDK5</accession>
    <name>A0A010YDK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709038.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.392"/>
    <dbReference type="HOGENOM" id="CLU_000022_47_0_0"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="304"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="744"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="844" mass="94642" checksum="218E2F9A9A4B150C" modified="2014-06-11" version="1">MKLSFSTFGWHDYTWEDFCAVAKDGGFAGIEVHNIHEPTLVKKNSIFDPARANAAHREMTEAGLSIPCIDAWHNIADGAKFEDNCAEIMDYINTAKSLRVPYVRLGAKDTGSSFADERAAVMRVLEKMLPAAQEAGVTLLIETIGIFSDTDKLCDVLNSFSCDNLAALWDMQHTFRDAGEAPEKTVKNLGAYIKHVHLKDSDVVDGVMEYRLICEGSLPVDAMMRALYSLNYDGFISMEWDPQWVPDIESIELISLHFVNTMNRFGNPARMVKSKRLYENKRGTGLYPWQKDKLIEKTFGAVLDRVVEEFPDQYAFKYTTLNYTRTYSEFRDDVDEFARALISLGVGPGSHVAIWATNLPQWYVTFWATTKIGAVLVTVNTAYKIHEAEYLLRQSDTHTLVMIKGFRDSHYDEIVKELCPELETAAAGKPLACRRLPFLRNVITVDFKMKGCLTWEEAVSRAHMTPLEEVHRLAAAVDIHDVCNMQYTSGTTGFPKGVMLTHYNVVNNGKCIGDRMDLSTADRMMIQVPMFHCFGMVLAMTASMTHAATLSPLPYFSTKASLACINQERITCFHGVPTMFIAMMEHEDFDKTDFSYMRTGIMAGSPCPISKMRDVVDKMNMKEIVIVYGQTEASPGCTMSDTGDSLEVRVETVGHALPEIECRVVDPETGEELPDEVPGEFVARGYNIMKGYYKMPEATAAAIDADGWLHTGDLACRTAAGDYRITGRLKDMIIRGGENIYPKELEEFLYTHPKVKDVQVIGVPDEALGEEICACVVLKEGEEATEAEIKEFFLSHMARHKCPRYIDFVDDFPMNAAGKILKYKMREDAVKKYGLENAAAVKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDN1</accession>
    <name>A0A010YDN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GLUG motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_410341_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011493">
        <property type="entry name" value="GLUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07581">
        <property type="entry name" value="Glug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457848" evidence="2">
        <location>
            <begin position="29"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="653"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Glug" evidence="3">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="675" mass="69990" checksum="ECB7D707A8EE8ADF" modified="2014-06-11" version="1">MFDLLAAFKRKRCACFALLAMLTLLVMAACASQDGSWVESADTAWYESDKEASSYTISTPEELAGLAVIVGSGDAEGKKNDFKGRMIILAKDIDLSGKVWSPVGNYNAKFAGAFDGRGHTISGLGTITPLPSDKYGDYGLFGCLGQYSSVKNFILKGDVVASGDKYNYIGTVAGRLYYSEPVENCSFTGRLRGMTGKVNGGIIGYNEAGTIRNCSASADITADAANAKAGAYMIIGGILGKNFSKSTIENSAFTGSIKYDDNLSRMRVGGIIGENSSNNCIIQNCVVSADIDVSGGLGTDSYSDYNCAGGVAGYNDGPINNVAVAGTVKLHAEDGKNWVAAGGIAGVTGTGGNTYAHNSSVSCKVSASSLLPEKACAGALVGYVYRWTNEWEVEDKCKIINNRWVKGEGVPAPLAGNWNEISGDIGIDKAIVSNDAVESESNLPASAVLTTPLIRLVENKSFTLAATVYPTAAYNKSDVMISWNVSDPSVASLTADGASALVRGLAAGFTKINLSCGNLLGGENTYTPVTGTAVYRVKMEGLELSPRAISLDAAGASADITATILPDSDTPSYPVLKWTYEVVSGDNASADDILLSFGDSSLKAKVTLKNHVEGAVYRITAGGVDDSSLTDSILLTATAAQPSGGGSSGGCNAGFAGFAALALFLPCALLFRKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDN6</accession>
    <name>A0A010YDN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_198854_6_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024419">
        <property type="entry name" value="YvrJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12841">
        <property type="entry name" value="YvrJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="51" mass="5640" checksum="892FFBEF0F1F584C" modified="2014-06-11" version="1">MDELTGSMIQNGFSIAVASFLLIRMDKRLEELTKAVINLGSVMEKAARPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDP8</accession>
    <name>A0A010YDP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyruvate-formate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441625.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.460"/>
    <dbReference type="HOGENOM" id="CLU_009096_0_1_0"/>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0556">Organic radical</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PFL" evidence="5">
        <location>
            <begin position="3"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="4">
        <location>
            <begin position="666"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="657"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2">
        <location>
            <position position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="786" mass="88502" checksum="4E0CF112A90472FE" modified="2014-06-11" version="1">MNERIRRLRDESFDTHPSIDIERALLETEFYRENEGKLPMPVLRAANFKHICENKTIYIGPEELIVGERGPKPKAVSTFPELTCHSRHDFEILTTRAQQNYTVAPEDMETYEKVVEPYWRGRCMRDRLFERMPEDWTLLYEAGTFTEFGEQRALGHTALDGLIYQKGALDLKKDIEEARAKLDFINDPDATAKDEQLQGMSISCDAVIIFAERHAELAEKMAAEEKDERRKAELLKIAEVCRRVPAHAPSNFWEAVQMYWFVHLGTITELNGWDAMSPGHLDQHLAPFYAKGIAGGTLTRDEAKELLSCLWIKVNNTPAPPKVGVTAKESGTYNDFTNINLAGLKRDGTDGSSEVTYICLEIFDELRLLQPQGNIQVSERTPDNVLRAAARVFRNGMGYPSMFNADMVIQEQMRVGKTLEDAREGGTSGCIETGCAGKEAYLLHGYLNVPKLLEYALSNGVDLLTGKQVSIKTGELSEFKTFDDLYAAFEKQMAHAIETKIGVDNYLRYQYATNMAATYLSCVIRDCIQKGKDYYNGGPRYNSDYIQCCGIGTITDSLSAIKKHVYDEGAYTLQQVVEAMKANWEGHEEMRLTLWNKTPFFGNDDDYADDLMKRVYNSLFNNIDGKRSILGPTYHLNMLSTTCHNYFGQKLAATPNGRFSGMPESDGTSPSHGADRNGPTAVAKSLAKMDQVKSGGTLLNQRFLPSVLAGEEGIEGVKNLIRSYFKLGGHHIQFNVVDEETLRDAQANPDNYRGLLVRVAGYSDYFVDLDNYQQEEIIARNAQEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDR1</accession>
    <name>A0A010YDR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484825.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.475"/>
    <dbReference type="HOGENOM" id="CLU_001681_2_3_0"/>
    <dbReference type="OrthoDB" id="117507at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="948" mass="104679" checksum="9001903E493EAF5B" modified="2014-06-11" version="1">MAKEMTEAQLAASYVIKKLTINGVPRRVMGKPDVTLLTVLREQLKMTGTKRGCDCGQCGVCNVILNGKVVRACITRWKNVPEFSEITTIEGIGTPDNLHALQWAMIVCGAIQCGFCTPGFITCGKALLDQNPNPTREEVRDWFGKNWMACRCTGYKQIVDAVMKAAAILRGEEKIEDLAKMYKPGDKVWNSSYPRPNAVFKATGLWDFGDDDRLKLPEEFLFAYPYALEGVRHAKVNKIDVSEAEKCEGVVKVCTYKDVKGTNRLRGQIGCDSAVVDGWERRIMVEEGDKIRQWGDIVAVVVADNEKHARAAAQKIKVDYEQLPELVDVREAIKADAVSVFDDCPGIDGMPNAWNKRCFAKGDDPSDIIANAPHKVDDEFYSSRQPHMVLEADCGYAYYDDEGRVTIHSKSCAIYFAIVKLARGIGLPPSKIRIIENNMGASFGYKTTVTNEQYLALALMATGRPVYMRVNMKEHNQRTPKRSPSFMHIRAAADEKGKLIGVDGTCWIDHGPCSESANDLTNKSGQFFFSPYAYDNMRVTAYTIWTNHRWSSAFRAYGSPQIYWGAETAMDMLAYECGMDPFDFREQNLLEWEPFTENPRGHFPSGHAPEVFPLPEMMKKARPVYEEMKKKAKELSTPEKKYGVGISVSIYNANDDGADESASNIELLKDGSVMIYNTWEDHGQGADIGTVGTAHEALKPLGIAPEQIRLFMNDTARCPNSGAAAASRSQTMTGNAIVDSCKKLLDAMRKPDGTYRTYDEMVAENIPTFYEGKSQAQVLHKDGSVESCGGNDKDTGIGKPFAFHMFAVNLAMVSVDMNTFKAHCEKFVLCGDVGVINNYLVVDGQQYGGIAQGIGLALTEDFLDESKYNNFVTMGFPYIKDITDDLTLIQSEVPRPLGPFGASGTGEMPLSGPHAAVGNAIYAACGARVKTIPAIPARIKAALEETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDY6</accession>
    <name>A0A010YDY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type proline/glycine betaine transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0534</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484839.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.573"/>
    <dbReference type="HOGENOM" id="CLU_028473_1_0_0"/>
    <dbReference type="OrthoDB" id="485527at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="101"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="296" mass="32784" checksum="E3EEBA8DB3B24771" modified="2014-06-11" version="1">MDFVQQYILNFPQSWQFKAGKVIDAMVMEFARDHRSGLELIKSGIIFMINCVRWFLSSVPWVVIVLFVALLSWYLMKKWYVGALYGAMLIFIGSCGLWNEMIETLSIVVMGVAVCVVLGFPLGVFLAVNPRANRIVRPILDTMQTMPSWVYLVPAVLLFQVGMTPALIATATYAIVPMVRMTSHGLIYVDKEMLEASYAFGSTKIQTLMKVQIPQAKPTIMAGVNQTIMMAMSMVVTCALIGAKGLGMEILIATNRVEVGRALFPGICIVMLAIILDRLTQVAVKRQDVLGEEADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE06</accession>
    <name>A0A010YE06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase, imidazolonepropionase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_2_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="63"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="406" mass="43421" checksum="3C091CC0AED9CA09" modified="2014-06-11" version="1">MKEGFCMYSIVKCGTLIDGTGAEPTVGAALLLKDGLIVSSGKYEEVAKEAPAGAELIDYGDKYVTPGIIDAHVHVTIDPEADFTGFVGRDSDTRIAHRGTVNLKKTLDGGVTFIRDLGGYHHIDIELKKLIDEGLIEGCGLLASGEMITMTGGHGWKIGRECDGPSEARKAAREQIKAGATVIKIMATGGNLTPGPQGAPQLSEEEIRAAVEEAHKSGKRTTTHSHSAEGVKNALRAGIDCIEHGMFIDEEALDFMKAHGIPYVPTLVAPWICAMVGEERGLSKEAVEKTKSAIGRHMESFRMAVKKGVKIAMGTDAGTPFCEHGKAYVGELRLMTEGGFTPMQAIVAATKSSAEVVGVEKSRGTLEAGKEADFLILAENPLDDLGAFEHIREVYKGGRRVERKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE45</accession>
    <name>A0A010YE45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_219025_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="41" mass="4432" checksum="19284AF2C5AD0D46" modified="2014-06-11" version="1">MDAMTNVLFCNYPVSTGCLIIGTVVFAAIGTISFYLGKWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEK8</accession>
    <name>A0A010YEK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ethanolamine utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial microcompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710663.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.820"/>
    <dbReference type="HOGENOM" id="CLU_1270774_0_0_0"/>
    <dbReference type="OrthoDB" id="1164040at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044870">
        <property type="entry name" value="BMC_CP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030983">
        <property type="entry name" value="EutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009193">
        <property type="entry name" value="EutL_PduB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012290">
        <property type="entry name" value="EutL_PduB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04502">
        <property type="entry name" value="microcomp_EutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51931">
        <property type="entry name" value="BMC_CP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC circularly permuted" evidence="3">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="BMC circularly permuted" evidence="3">
        <location>
            <begin position="114"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="216" mass="22317" checksum="8C42DDFF9D96F328" modified="2014-06-11" version="1">MKRDPLKANVLATQIIPNVDPSLAKELGLSPSQRSLALITSDSDDVTYTALDEATKAADVQVVYAKSMYAGAGNATTKYVGEIIGILAGPNPAEVKSGLAAAVDMIENVAHFVSANDDDSVPYYAFCISRTGSYLSKVAGIAEGEALAYLIAPPLEAVYGMDAAMKAADVSMCAFYAPPSETNFGGGLLTGSQSACKAACDAFAAAIEYVAENPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEP9</accession>
    <name>A0A010YEP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0813</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442040.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.865"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="322" mass="36491" checksum="0DC987D0474BB60A" modified="2014-06-11" version="1">MNDNILLDVRNLRKYFYKDEGLISKKIQEIKAVDNVSFYIRKGETLGLVGESGCGKTTVGRTVMRLYEPTAGEIYYDGIDVAKLPARSFMPYRKKIQMIFQDPYASLDPRMTVADIIGEPLDIHRIASGKERQERIFELLKRVGLRKNHANRYPHEFSGGQRQRIGIARALSVMPEFIICDEPISALDVSVQAQIVNMLEDLQQEIGLTYLFIAHDLSMVRHISNRVGVMYLGGLMEVTTADELYNNPQHPYTIALLSSIPIPNPRAEKNNIILEGDVPSPLNPPSGCRFRTRCRYAKKICSEAAPEFKNLGSEHYVACHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEQ4</accession>
    <name>A0A010YEQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative permease, DMT superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442045.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_15_3_0"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="148"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="286" mass="30977" checksum="59C36BA4F90E7DC6" modified="2014-06-11" version="1">MNSRNRGLMNIHIAVLLFGLTALFGRYVSLPAPYIVLGRVFFASLSMGIYFLIKGHNICLSKKADYIVICSIGALLAFHWTAFYTSVQVSTVAIALITFSAYPIFVTFFEPLMFRERLKKADAFFALIMFMGVLIIVPELNIENNLTVGLLWGLAGSVSFAVMSLLNRKFASSYDGSVIAFYEQGVAALVLMPMIFFHRPAVDARDWGLLILLGVVFTGVAHSLFIGGMKHIRAQTAGVIASLETVYGILSAALVLGEVPSARELAGGALILGMAVCSTLKSSKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YES0</accession>
    <name>A0A010YES0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rrf2 family protein, putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710782.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.886"/>
    <dbReference type="HOGENOM" id="CLU_107144_0_1_0"/>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="152" mass="16891" checksum="79A2512F3FA05BBB" modified="2014-06-11" version="1">MAITQKCQYALRAIYELARRQQEGPCKIGAVAEAQNIPVRFLENILSSLKSAGVVDSARGKDGGYFLAKPADAITVGEVIRFIQGPLGPVECGTRMEDDCSLYEDCVFRPLWDKAREALEVVYDGTTFQDLVNQSDNSCHRPDCWCGKRIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEY3</accession>
    <name>A0A010YEY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.940"/>
    <dbReference type="HOGENOM" id="CLU_081251_3_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="107"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="48"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="2">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="195" mass="21483" checksum="67F0CAC26C892D94" modified="2014-06-11" version="1">MPPLAGRLLRVFICIKLPQGHTDALGEWLAARRSAETGIRWVAPETIHITLKFCGEIHPDMTEAIAKLLNKEDIGGPVELSVSGVGGFPSLSAPRVVWTGIGGEIGKLKKLQQKAETCAFRCGVAKEWRKFSPHITLGRRNEHGPLPEAAVKAIEKDKIELPAWRVKEIVMMKSELTPGGPIYTPLKHFELRGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF93</accession>
    <name>A0A010YF93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="7">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gpsA</name>
        <name evidence="15" type="ORF">Cloev_1031</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 11">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484900.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1101"/>
    <dbReference type="HOGENOM" id="CLU_033449_0_2_0"/>
    <dbReference type="OrthoDB" id="1419877at2"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10 11" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="13">
        <location>
            <begin position="17"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="14">
        <location>
            <begin position="192"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="267"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="22"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXG78885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="345" mass="36820" checksum="4568D64652D0AC67" modified="2014-06-11" version="1">MRGIRGMRILNGGTTLNITILGAGSFGTAMAVHLASLGHNVKMWTIDGKQAETINGSHRNNFCFFDTALPVNISATTGLRESLDFSDRYIMAIPTQFEREVCGKIAALAPAPGHMLNLAKGIEISTGNLLHKVHRELCPQMVYSALSGPSHAEEVLIDCPTTVALASGDEEEAKSWQKLLNGGNFRVYTSTDVIGLEVGGATKNIYAIAAGISKALKLGDNALAALASRGLAEIMRFGAKLGASPLTLSGLAGVGDLMVTCYSMHSRNFRLGLAVGSGMSMEEAVAELGQVAEGAYTVRAVIENSKKFNVEMPLADAVYRVLYKNEDPKALLKELFARPVKSEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF95</accession>
    <name>A0A010YF95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711074.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1107"/>
    <dbReference type="HOGENOM" id="CLU_043930_0_1_0"/>
    <dbReference type="OrthoDB" id="1725392at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038728">
        <property type="entry name" value="YkvI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37814">
        <property type="entry name" value="PTHR37814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="363" mass="38839" checksum="ABC171E190BAFA29" modified="2014-06-11" version="1">MSGNKVSWLNVVKFAGAFIAFLIGAGFATGQEVFQYFAAYGYEGFLVGLFVLVCFVYVGGDFIVSGFNEHFKNTNDIYRHYCGKYIGGFYDYFSIAFIFMSYIVMLGGAGATVNQYYHISPVLGAILMMVLSVGTVVFGLGKIVDVIGAIGPLIVIIAIGVGLAAIVTNPGGIAEGARLITSGELDITRVGSNWFMAGTSYVGFCMLWLAAFLAAMGTKANSKKEAVLGTTIGAIGFVIGALILMLGLLSSLQDLYTSDIPSLIIAEKIWPPLATIFSVIILAGIYTTAVPLLWSVSARFAQEKTTKFYGLTAGLAAIACFVALELPFRQIVNIIYGVNGYVGILLIFFMLAKSFGITKKFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFC8</accession>
    <name>A0A010YFC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cloev_1091</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442405.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1160"/>
    <dbReference type="HOGENOM" id="CLU_014881_3_2_0"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12837">
        <property type="entry name" value="Fer4_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="13" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="567"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="597"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG78935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="624" mass="67529" checksum="D33344CC1FF7A70B" modified="2014-06-11" version="1">MIKTREELRKLREIYAASLGEEDKKILICAGTGCISSGSLEIYDELKKIMEERGINVAVELREEPHEHSVGLKKSGCHGFCEMGPLVRIEPQGWLYVKVKPEDCSEIIEKTIVGGEHIARLAYAKNGEIYKKQGEIPFYKKQTRHVLEHCGHIDATSIKEYLAIGGYSAFERALFDMNGDEIVGMIEESNLRGRGGGGFPTGRKWSQVKRQNAEHKYIVCNGDEGDPGAFMDRSIMEGDPHRMLEGMMIAGLACGAQNGYIYVRAEYPMAVSRLRTAIAQAEELGLLGGDILGSGFSFRMHINRGAGAFVCGEGSALTASIEGKRGMPRVKPPRTVEHGLFDSPTVLNNVETFANVPLIINKGVAWYKTLGPEKSPGTKAFALTGNIENTGLIEVPMGTTLREIVFEVGGGMRGGADFKAVQIGGPSGGCLTVKDLDLPLDFDSLKAAGAMIGSGGLVVMDSRTCMVEVARFFMNFTQNESCGKCVPCRGGTKQMLAILERIVAGEGREGDIDLLLELADMISHTALCGLGKTAALPVVSTIKNFREEYEAHISKKYCPVGACAKLKSFEIDPALCKGCSKCARGCPVEAICGKIKEPFTIDKEKCIKCGACVTACPFHAVKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS42</accession>
    <name>A0A010YS42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter membrane protein 1, PhoT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708525.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.27"/>
    <dbReference type="HOGENOM" id="CLU_033621_1_0_0"/>
    <dbReference type="OrthoDB" id="1325025at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="58"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="281" mass="29789" checksum="3F5267C3AB44CAC3" modified="2014-06-11" version="1">MIDSPNTPFWLRASAFYVTALLATVFVFITFCAAEGLFMSGPTLFTSVWHPETQEFGILPMIAATAALSLSSLAIGWLVAFGCICHIYGFGGKYSASLLSSLLRIMTAIPTVVYGFASVFLLVPLIRDGLGGSGFSWFTAALVLSLLITPTMVLTMESAVSQVARESGLTAEALGLSRAEHLVCVVLPACREWLWGAALLGFGRAAGDTMIPTMLAGNAVQYPTSPFEAIRTLTAHIGLVLSSDVGGTAYYSLFVAGGILLVLSTGANIIFRAVRRGRNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS58</accession>
    <name>A0A010YS58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.52"/>
    <dbReference type="HOGENOM" id="CLU_106201_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="227" mass="24154" checksum="0547754574C3B117" modified="2014-06-11" version="1">MLLGTMLNNQAQAQAEANAIAKQQAYERKVAEVQNAARDIASTQSAHVMQIISQAGPEYALQDLNSYWQAQGQATFLDARTPVSVLKVAGFQQELTILYTVDQSRQNVTVTVNAPQYSISESSTAQYTPPAPAAPAKSAARMMGFTVADDARSPEGFLLVRDVTPATAAAYVGLKNGAVLYKIDGYSTAQVGVEQMGAYIKGRADADAAVEITFSDGGKQKTANIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSN7</accession>
    <name>A0A010YSN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DMT(Drug/metabolite transporter) superfamily permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709412.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="156"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="293" mass="32648" checksum="2AFA260FFFD3DD4D" modified="2014-06-11" version="1">MRAWTKDGKMMSYGLAAVVTMIWSITFVSTKFLLNYLSPAEILLYRVILAYFIFVMMDPRFIRPVSLREECRFALMGFLGTTLYFLGENFALEYGTASNVSLLVSTAPLLTGIVAHFFVKSERLTKRFAIGGLFCLGGVSLIIFNGHFILKLSPVGDFFALAAALSFAFYSVTVRNMSRGYAMTVITRKSFFYALLTLLPLTLTPLINWHPQDLFRVDVLLNLLFLGALASAFCYLAWNKVIWALGAVKANNLIYLTPPLVIINAAVILRERITPFAVAGGLLILVGVYISQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT62</accession>
    <name>A0A010YT62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441688.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1014540_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="274" mass="29721" checksum="324B6AFF42636786" modified="2014-06-11" version="1">MKKWRCPRGLFERTGGIDGDFLAESRGAAMETFDCDPQNAGCDCYGCDGPLEVSSHGRVKHSEVEARSEGCVPAPVDGGVVEGGIVPASSAAVIFGGEVREDDVIETEFAQGQQPLGGEDVFPPSYEEVVGSAPNVTEAQRRLLFVREQMQAADRAIKDIKKDAVAPFQGEITENQRRKDMLAIAFDFYVVQSAIEEARVKSLHEDPIFCAYIAATEKKFLKVKVGTRQDVREAAVKYGEANVYVFGEFQEGQDVNAPAAEAGKDCRESEEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTC1</accession>
    <name>A0A010YTC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type transport system involved in Fe-S cluster assembly, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0537</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441785.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.576"/>
    <dbReference type="HOGENOM" id="CLU_000604_48_1_0"/>
    <dbReference type="OrthoDB" id="1214676at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="265" mass="28728" checksum="860A51096ED9541A" modified="2014-06-11" version="1">MTGDKLLEIEDLHVSVEGRAVLKGVSLSVGEGEIHALFGPNGSGKTTLLNTVIGFSRYKITRGAIYFKGRDITGATIDERARLGVGISFQRPPTIKGVTLRSLISFGSPNLSREEIEKTAAKLDAEEFLDREINAGLSGGEMKRTEMLQIILQSPELVCLDEPESGVDLENMALIGKAARIALGRDSFDGAACRRSIKSRRADYKSGLIITHTGQIMDHLYVDKGHVLMNGEIVCSGNALELLGEIRSHGYTECFRCAGCERSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTI7</accession>
    <name>A0A010YTI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Citrate lyase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0618</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710361.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.662"/>
    <dbReference type="HOGENOM" id="CLU_044864_0_0_0"/>
    <dbReference type="OrthoDB" id="1107373at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="5">
        <location>
            <begin position="5"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="294" mass="32428" checksum="CFB86BBDEF75216F" modified="2014-06-11" version="1">MRAFRSMLYIPADAPGMLQHAPIFGCDSILMDLEDAVAYTEKDSARLMAAWFLREFDFKDLFVTVRVNGADTTFFDDDVSAVVPCRPAAVRLPKCNSEADILYADKKIAEVERQNDMPLGTVKLHAMVETALGLENAFRIATASPRVTALTLGGQDFTADMGIQKTRGGRELFYARSRIVAAAHAARIDSFDTVWTDLNDQEGLFLEAKEIVELGFTGKACIHPSQISVIHKAFMPNEKDLRKALRVVEAAEKAEREGKGVISVDGKMVDAPIVARSAHLLELAELYGFDREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTM2</accession>
    <name>A0A010YTM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441897.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.694"/>
    <dbReference type="HOGENOM" id="CLU_027562_33_1_0"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="190" mass="21434" checksum="4D230415F4F689CC" modified="2014-06-11" version="1">MELVEPIRDTKKIDRMKKYLKEKSTRDYCLFVLGINSGLRISDLLNLQVKDVEDDSGKLKDRIHLTEQKTGKAKDFPISDTAGKAIREHLSSLNTKEPLAYLFPSRKGTAAITRVQAWRILNDAAAHSGLDKDAIGTHTMRKTFGYHAYKMGMDLSVIQKLLNHSSPAITLSYIGITRDDLDNVYLNLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTP2</accession>
    <name>A0A010YTP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441922.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_5_3_0"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="77" mass="8074" checksum="963BBB1FF8934A23" modified="2014-06-11" version="1">MPKGRVEISEKYCKGCSLCVYACPRKVLAISGRINAKGYRPVEAAKADDCVGCGLCAMTCPDAVISVFREEEGGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTP8</accession>
    <name>A0A010YTP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710461.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.720"/>
    <dbReference type="HOGENOM" id="CLU_060196_2_1_0"/>
    <dbReference type="OrthoDB" id="1027643at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="1">
        <location>
            <begin position="22"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="272" mass="28681" checksum="2D869CF7320512D7" modified="2014-06-11" version="1">MQIAVLVKQVPAVDTVKIDENTGTMIRDGVEAELNPLDLHAVEAAVRIKESRPGVEITAVTMGPQAAQKAVKYAIAMGCDRGLLLSDRKFGGADTLATARTLSRALLKAGPFDLLFAGERATDGETGQVGPACAELMGIGVLSYVSAVEELTDEKIRVVRAVEGGHETVESPLPAMVIPVKEMNIPRLCTLGGKLRAKEAEVPLETADGLSMDAAETGLTGSATQVVNVTYPKVTRQGRKVIASEDLGAAINEIMTLLEEKNCLEETGGDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTT0</accession>
    <name>A0A010YTT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441956.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.754"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="314"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="8"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="426" mass="45126" checksum="CE7B2F08DD1C63E8" modified="2014-06-11" version="1">MEAVILFSLLIVTIGLSIPIGITLGLSTGIAMWLTSDIPMVMLAQKSVTGLDSFPLLAIPFFILAGALMCNGGISRRLVNLAESLVGYITGGLAMVTVLACMFFAAISGSGPATVSAIGSFMIPSMKERKYDAGFAAAITAAAGTIGVIIPPSIPFVIYCIVAQCSIGDMFIAGIVPGVMIGVALMLVCYCTAKKRHYVSVTERPKLATVWKAFREAFWALLVPVIILGGIYGGIFTPTEAAVVAVVYSVVIGKFVYKELDGKTLYECLRTTGLINGATEFMIGLSMAFASYLAMAQIPAHIASWMTSLAHSPFILLMVINVFLLIIGCFVDNIAAVIILTPILLPVVKAIGIDPIHFGLIITVNLACGFISPPYGINLFVASAISGESIEDISKAILPSFFAMVVCLLLFTYFPIFSMGLLNVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTU3</accession>
    <name>A0A010YTU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gate domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710596.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.765"/>
    <dbReference type="HOGENOM" id="CLU_048533_0_0_0"/>
    <dbReference type="OrthoDB" id="819609at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="2">
        <location>
            <begin position="139"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="450" mass="48767" checksum="33BBD335C6C09025" modified="2014-06-11" version="1">MAAKQKYTSAQIMHFLIPSLIGAIVFLLPIPMKGSLNTILGIAIDWGKAILKPWLPGTAMVLVVLSALASLWATLCKPEKIAKDSFWGELLIVRPFWLASRLLGAALYIVIFFKLGPEIVWNMDNGGTPAIILAPALLIIFIVLAGVVPLLTDYGLMEYVGTYARPIMGPMFKLPGRSAVDCLASWVGSCSVAVVITTKVHDQGYYSDREASIITTAFSVISIAYIYVMADFVGLPNMYFQIMAAVYAVTFILALIMPRVWPLSSMPDTFSGKAGKQRIGDDIPKGYSLGDWAIKLAVERSAKQTTAMTIDSGVKTFVSLVVSTMPLVVAWGTVVLIIANNTPVFQILSAPFAWCLQLMKIPEAKEVAPAFLLAYADQFLAAVVGSGRTAVAAKFMCACISGTGLIYMTEVGVLILQSSIPLGFWKLTGIYFIRAVLSVFLLAPFAWLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU85</accession>
    <name>A0A010YU85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0847</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484877.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.901"/>
    <dbReference type="HOGENOM" id="CLU_024867_1_2_0"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="492" mass="53455" checksum="FFC30DE878E58873" modified="2014-06-11" version="1">MNIGDQIEHLLEYVAWTILWNKYFAVMFLVLGLYLTIGLRFFQFRRFGDIMRNTIGTLFRKKDTVKKESSNNVSSFGAFATALGSTVGNGNIAGVASAIAIGGPGAIFWMWMCALVGMATKMSEIVLTQTYKQKDNTGISRGSAAYYIQKGLVEEKGWKWCKVLSVVFTVAMLSAFYFTPGPYVVAESVQAGFNLSATGAIIFSFIYVILQFIIILGGIKRIIKFAESAVPFMVVAYFGVAFFLILKDIPATIEAFKSIFYYAFNPTAAVGGFAGASIIMTLQVGVARSVYSNEAGWGSAPIIHAAADVDHPARQGLWGAFEVFVDTIIVCTITGLMVVITGVWQAGEGGAGSVGKALSHVYGPVGGMALAIFIFIFSLTTSTGWYAYLEALVGFMVRDKPAETRRKIVKFITCTGPLFGLGATMFFFSHGTVPAVAWMVLDIQSAIPVYVNVIALTLLSPVIFKKVREFETDFLDPEKAAREAARGKLAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUE2</accession>
    <name>A0A010YUE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcription factor, MBF1 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_17_5_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="130" mass="14851" checksum="2C32E7DFE999C1A4" modified="2014-06-11" version="1">MWKIQKYRIARRLTQENLAEKVDLSVSYISEIENGKKRPSLKTLEKIAAALEVSLVSLMGEDDKKDAEKENQIECPFLKYTGDNGEIAAANGITREIFAVVAELPMEEKIKVLSYVRDLKKLSDFMKDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUG3</accession>
    <name>A0A010YUG3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442155.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.977"/>
    <dbReference type="HOGENOM" id="CLU_146491_1_0_0"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025979">
        <property type="entry name" value="ChrR-like_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12973">
        <property type="entry name" value="Cupin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_7" evidence="1">
        <location>
            <begin position="29"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="133" mass="15280" checksum="18C331751C291CF1" modified="2014-06-11" version="1">MAKQEYEIRDVDLRGEWRLVEGGYNGTMEKVLSYDPETGNYTRLLKFPPQTEMPEVLSHDFCEEIYVVDGYLTDTNKNLTMAKGYYGSRLPGMKHGPYSIPLGCMTMEFRYQDPNKPVDPECSLLKNKLGAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUM5</accession>
    <name>A0A010YUM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplO</name>
        <name evidence="8" type="ORF">Cloev_0998</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711015.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1067"/>
    <dbReference type="HOGENOM" id="CLU_055188_4_2_0"/>
    <dbReference type="OrthoDB" id="1874945at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="7">
        <location>
            <begin position="27"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="148" mass="15728" checksum="136D49AEF7334050" modified="2014-06-11" version="1">MKLHELSPVPGSRKKKKRLGQGLGSGQGKTAGKGHKGQKARKSPDIGANFEGGQMPLARRIPKRGFSNFRFAVKYEIVNIADLEERFEAGAEVTAKELTELRLISDAAKPVKVLGAGELSKSLNVKANAYSSSAAKKIEAAGGKAEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUV7</accession>
    <name>A0A010YUV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prepilin-type N-terminal cleavage/methylation domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711205.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120517_0_0_0"/>
    <dbReference type="OrthoDB" id="2088200at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="153" mass="16902" checksum="656C56CA864D7374" modified="2014-06-11" version="1">MKKMIKKYRKAKGFTLVELLIVIIIIGILAGMMMLSTGSATDTAEATKIVSDMRNIKSACLMYYAENRVWPKATDIESVDKYLDTQTDTTKYNLEAGVKSGDLNVTGTTKEAGVQKKLVTMAADAGLYDDNTATKIIKTPQDKVHMIIKKDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH43</accession>
    <name>A0A010ZH43_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methylaspartate ammonia-lyase</fullName>
            <ecNumber evidence="6">4.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Cloev_0147</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3S)-3-methyl-L-aspartate = mesaconate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12829"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:36986"/>
            <dbReference type="ChEBI" id="CHEBI:58724"/>
            <dbReference type="EC" id="4.3.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-glutamate degradation via mesaconate pathway; acetate and pyruvate from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methylaspartate ammonia-lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.2" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709238.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.158"/>
    <dbReference type="HOGENOM" id="CLU_055277_0_0_0"/>
    <dbReference type="OrthoDB" id="254720at2"/>
    <dbReference type="UniPathway" id="UPA00561">
        <property type="reaction ID" value="UER00618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050096">
        <property type="term" value="F:methylaspartate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019553">
        <property type="term" value="P:glutamate catabolic process via L-citramalate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006395">
        <property type="entry name" value="Me_Asp_am_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022662">
        <property type="entry name" value="MeAsp_NH4-lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022665">
        <property type="entry name" value="MeAsp_NH4-lyase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07476">
        <property type="entry name" value="MAAL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05034">
        <property type="entry name" value="MAAL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017107">
        <property type="entry name" value="MAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00007">
        <property type="entry name" value="methylaspartate_ammonia-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01502">
        <property type="entry name" value="B_methylAsp_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAAL_N" evidence="14">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="MAAL_C" evidence="15">
        <location>
            <begin position="164"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>(2S,3S)-3-methyl-L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:58724"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>(2S,3S)-3-methyl-L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:58724"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="12">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR017107-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR017107-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR017107-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR017107-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF05034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXG78044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="416" mass="46045" checksum="A86FC0DB82FA19F0" modified="2014-06-11" version="1">MKVKKVLCSEALTGFYMDDKEAIKSGAKSDGFVYKGAPVTPGFKSIRQPGVAVSVMFVLEDGHVVYGDCAVAQYAASGGREVPNTAAALIKVIEKYVTPYFEGMDIKEFKSTAEKFDRYEFDGERLPASIRYGVTQAILEAAAYEQKLTMCEVILNEYNLPVDLTPVRINAQSGDERYTNVDKMILKKVGMMPHGLINNVEEKLGKDGQIFLDWVKWVTKRISDIGEPDYKPVMRYDVYGCMGKAFDNDLDKVGEYLIKVADACAPYEVFVEMPVDMKSNEKQLEAMKYLRKYLDDAGCRLKLIIDEYANTYEEIVEWVDAKGADMVQVKTIDLGGINNIVEADLYCKAHGVLAYQGGTCNQTDKAAIVCANLAVATKPFAMAGTPGMGVDEGVMIVSNEQERLLAILKAKQEGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH67</accession>
    <name>A0A010ZH67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding protein with HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484778.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044466_0_0_0"/>
    <dbReference type="OrthoDB" id="1307478at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="397"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="472" mass="50054" checksum="D03561D68F0A4F5B" modified="2014-06-11" version="1">MNKSIAPPRAEINVSVFNGTYYALYMFIFLLAELVIQDRAAAAVGAEAVVPAYCVGLIATAAGYLLLPLSRALVRGEAARRAMLVCAGAIFLFSFGLIVFVGSPFFFMLLAAVAMLAIGYVGAFVHYAAAVDMDGSPHLGITVGGAVCAAVLIQYLVQNYTKTAPALMASAAAALALSLWMPLKGQKDERRPLRPGAEESPKTANDKLTCVIAACLMSAAIGISDAIVTDFSARGDVTLSAYPRLFYAVSLVMAGFIADIKDRRCLPIATVCVLLFSVIVTSFLEGSFGFVISLATLYFLGGFVILYITLAFMEMAPRTAAPALWAGMGRVVRSLTIGFIAVPGVKLFQHAGHHLLTIISICLSLAVLLLFYAAGKLNNSSGEKSPAGGTAASFAGRYGLSGRENEIAELVIMSDDSINELAEQMAISGRAFQRSLTAIYEKTGTKSRLGLLRLYYECLAEEEAARESDTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHG1</accession>
    <name>A0A010ZHG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441420.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_515492_0_0_0"/>
    <dbReference type="OrthoDB" id="846018at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="523" mass="56418" checksum="699946D7DDB3A3AF" modified="2014-06-11" version="1">MTERVKYAAGTAAAAVILAVLFFTYTLWNSSGILTMIPKPEGSRPYVLTETKEGSYPKALSALLTDGVYALLKGGTPRNALLSATSAAKEAALLVEDGGEGMTEVYASFRFAPSDTSALKKGSLPEALKTVFKGASVRAGSEKGVFTIEAEGLSSPVYYTVKGKNVLMAAELSALRRMEDASKKSSANLGGKKWRQEKSWPAHIEVSDGGVITAGAEHKFPIMIEAAWHSLEPKNPSDPAGEIRWALVDLGKPVEAYLSSSLKAKKWDTADCIIPEPLLLSMGINLPPLGGDPRDWPFPLSSLGEIAENLDMKEAQIREILSGQTVFSLGGQNRILWFSLPGFLVEFSGRTELMNELVDSFWKNLFFGAEPKPLPGFTFGGTTNVPFSVIGAGRDGIAVLGLTTPQSINAKNRLGKFLKEDEAVVGWMLADLPRIGGALSEMTKMSSFLEEEGMEDSGPYGDYQGYGDNEQLAEPLQPDLSLSPFDQGITDSFGSVLKQLGRVLIVWEKPLSGRINWYKTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHL3</accession>
    <name>A0A010ZHL3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708948.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_27_0"/>
    <dbReference type="OrthoDB" id="1031685at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="204"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="262"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="470" mass="52405" checksum="AB270896E35EE1A0" modified="2014-06-11" version="1">MKSLWRAVKPDSLFGFILLVLILGAAANQFINFYAVCSIQHSLAREVLGIGHDYVSSVYQALNTMEGPQREAYLKKLDSSRGVMRKPFRFRMVPAPAWQSEDYYKSVNMKNAVAGAIGAAGADVPDIRARMLWPESPEATSSDYAGYIFPMLQVLIAMDDGGWLELTQPLSITDNRLVWRQRIFVLFESLIFSLIVIILIRCAAKPIERLAQEADRFGRNPEAACPLDERGSREIREAAQSFNRMRARICDNLNERNNMLEAMGHDLRTPLARIQLRLDRIEPEELREKFAANIEEIRSIIEQGLELARSLHTSEKAAPMDVVAFVESIADDMETKEGDIRLGAMPDDDAPLLVRARPTCLKRSIENLLTNAVKYAGGAVVSVEKDRGDVVIKIEDDGPGIPEAMLEKVFEPYYRLEGSRNRESGGTGLGLSIARNMVLLNEGSLVLKNRPQGGLCAMITLPAIEAKKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHL8</accession>
    <name>A0A010ZHL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0297</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708958.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.324"/>
    <dbReference type="HOGENOM" id="CLU_063199_4_0_0"/>
    <dbReference type="OrthoDB" id="1747063at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="215" mass="22901" checksum="AAE643481FAA6622" modified="2014-06-11" version="1">MGKNILLDLIRKNMEGLSPGKIVIIMIGTAISSFGVYNIHQLGVVTEGGVLGMILLANHWLGISPSIVTPVLDIACYSLAFKYLGGAFIRLSAVATLSLASFFRLWEQFPRVLPDMTGTPLLAALCGGVFVGLGVGLIVRQGGSGGGDDALALTIARVTKWKIARAYLVTDIIVLALSLSYIPLSRIAFSLVTVTVSSLLIGFIQEAKIFRPVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHP1</accession>
    <name>A0A010ZHP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441494.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.348"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_0"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="294" mass="33183" checksum="5CC8A9B3B90AD0B3" modified="2014-06-11" version="1">MLLRQMKYFTAVVECGSFTEAAEECFISQSAVSQQIQALENDLGVKLLHRESRGFSLTPAGEYFYRRARELLADAETMRRETVRIGLGERRLRVGYLKCYGGQELLQAAADFSRDHPEVSLQTISGTHEELYDALREGTADLVLSDQRRAFSDEYVNFHLLRCGCFAELSPAEPLAAKEYAALEELREMACILVSSKEQRRGEEEFYRGALGFAGKFIFAETLEEGRFMAAGRKGFMPVAAVGTLPPPASSIVRLPIRNADGPLRRNYCAFWKKDTENPYAELFAEILYKLLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHU8</accession>
    <name>A0A010ZHU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195100_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="70" mass="7794" checksum="6234C4264FA2A7BC" modified="2014-06-11" version="1">MIQISVSELKANVGKYVSMVNEQEIYITKNGKRVAKLTAPKQDKISAAMSLFDILPPEADLDKARMERLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHW7</accession>
    <name>A0A010ZHW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709081.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2715245_0_0_0"/>
    <dbReference type="OrthoDB" id="2079553at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021321">
        <property type="entry name" value="DUF2922"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11148">
        <property type="entry name" value="DUF2922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="72" mass="7753" checksum="79D618359212360A" modified="2014-06-11" version="1">MKTIRMKFITEAGKNFFVSMDYAAPELSGTEGAAKVQAAAELILEQQPFAVTLVSCEAAELIERTSTEIALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI08</accession>
    <name>A0A010ZI08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441681.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2116727_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="114" mass="13008" checksum="EC90408F35C6CD11" modified="2014-06-11" version="1">MKEFLEDLGQKPLTPDVIREYLNQGCEKVKEFEPEAFLIVGIKAEGEDIHSMVVTRFSCLEFVNILNGISRISPEIHQAMCAFSIEMLCDCIEEKDKDDCRDCPDEFRGDKSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI29</accession>
    <name>A0A010ZI29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441709.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1988760_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16332">
        <property type="entry name" value="Prp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007422">
        <property type="entry name" value="Peptidase_Prp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036764">
        <property type="entry name" value="Peptidase_Prp_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04327">
        <property type="entry name" value="Peptidase_Prp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118010">
        <property type="entry name" value="SSF118010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="125" mass="13283" checksum="714310E9C9F3EF04" modified="2014-06-11" version="1">MTKVRVFYAGSPPDAWVQGIECRGHAGGTRDGGADLICASVSLCMEMLEEGLRHVADPDVVTSVWICESRNPGGKAIHWEGDGAEVLAETVAATLRNIAAANPQNVSVEDVFNGEDKKDEKVAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI97</accession>
    <name>A0A010ZI97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative translation initiation inhibitor, yjgF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441807.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.594"/>
    <dbReference type="HOGENOM" id="CLU_104845_0_1_0"/>
    <dbReference type="OrthoDB" id="1956412at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14588">
        <property type="entry name" value="YjgF_endoribonc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjgF_endoribonc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="153" mass="16536" checksum="BEAFD031B6FD43C4" modified="2014-06-11" version="1">METEKRLAEMGVELYPDIKPIGSYLPFTRCGNVIHISGQGPSIRGEYVKYIGKVGENVTKEEAKEAAAVTAANLISILKKAAGDLDRVKQIVSVHGYVNSTPDFTEQPYVINGASDLLVKAFGEKGRHARCAMSVNSLPLGICVEVELTAEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZID9</accession>
    <name>A0A010ZID9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidinol dehydrogenase</fullName>
            <shortName evidence="1">HDH</shortName>
            <ecNumber evidence="1">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisD</name>
        <name evidence="6" type="ORF">Cloev_0602</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 5">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441851.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.642"/>
    <dbReference type="HOGENOM" id="CLU_006732_3_0_0"/>
    <dbReference type="OrthoDB" id="935289at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0520">NAD</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1 3">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1 3">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 4">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 4">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="418" mass="45223" checksum="AB609A3E183AD63F" modified="2014-06-11" version="1">MIVIKDAERNLTQEKNSVEEAVRDILSNVKCQGDKAILDYTEKFDKLRLNGIAVAKEEIKAAYGKVSPETIENLNFSAKRIQDFAEHQKSCLKEFSYEISPGVTLGHRIIPIESCGCYVPAGRYPLPSSALMSVIPARVAGVKRIAACSPANKEFGGIHPAVLVAMDIAGADEVYCMGGAQAIGAYAYGTDTLKAVDIIVGPGNKYVTEAKRQVSGNVGIDMLAGPSEVVIIADETADPKWVAADSLARCEHDPNSWTVIVTTSKAIVHKILSHIEGEAKALATAEVAMSSWKNNSRIILAEDMEEAVKITNDIVPEHLQVMTKDSREVANKLHNFGSLFIGHYAPVAFGDYVSGTNHILPTLRCSRFSNGVFVGTFLKMSSVQEITKEGAQMLSPHCAYLAGIEGLLGHQYSAELRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIF0</accession>
    <name>A0A010ZIF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710354.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.658"/>
    <dbReference type="HOGENOM" id="CLU_045683_1_0_0"/>
    <dbReference type="OrthoDB" id="988124at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005064">
        <property type="entry name" value="BUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042100">
        <property type="entry name" value="Bug_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42928">
        <property type="entry name" value="PTHR42928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03401">
        <property type="entry name" value="TctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017082">
        <property type="entry name" value="YflP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459060" evidence="2">
        <location>
            <begin position="25"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="327" mass="35124" checksum="5AC7074E0E799987" modified="2014-06-11" version="1">MKRSAAISVFAALFIAAFAFTAAAADYPSRPFEFLAPAGAGGGWDTTIRMVGKTLADQKIITQPMPVTNKPGGGGAVNLAYMQKKKGNPYTITVYSPPILLINLTGQTKLGYKDLTPISMLINDFGAYAVPKDSKFNNMKDVMDAIKKDPKSVKVGGTSSAGSMDHIQFLQAARAAGVKNLKEIPYISLQEGSMASLMGGHIDLLSTGMAETVGALEAGDIKVLAVSSPNRIKSGPLSKVPTLKENGIDTVFINWRGIFGTPGMGKAERDYMANALKKMAGTKEWKDVCMKNGWEPVYMDAGQFTKFLDKTNDEYKVILGEIGFLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIW4</accession>
    <name>A0A010ZIW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase, imidazolonepropionase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441999.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_2_0_0"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="55"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="420" mass="47263" checksum="6B9F7788498A5193" modified="2014-06-11" version="1">MSNYTLIKCGKLFDGIKEELQENVEIVVKDNKIEEVGKNLSVPNNVNVIDLSSVTVTPGLIDAHVHFQHFNWKERRNEIVFHNASWKAMAFLYNARKSLHRGFTSIRTVGSSTYDAYGVVNAKKLINMGYFEGSRLVALPHYHYSPGSHGDHSQYLAENPAISELMAKTAPTMGCGVDFFRNSVREQVKYGAEFVKIMATGGFSTPNDSPEDQQLSDDEMKAIIDTAHELHKTCTAHVYAGPLMKKLALMGIDGMEHGAMIDKEACRIMEERDIYLISNMAVYDDVIDINEESLAKKPIFFQRKLREYQGRLIEGRKIILESNLRLGYGTDFVAVHHPYDSGYEYESWMLSKIDPFRILKAATSINAGILQMADEIGTIEPGKFADISAWPRDLMTDSKALLDCCFVMKDGVAYPTEKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIZ0</accession>
    <name>A0A010ZIZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon dioxide concentrating mechanism/carboxysome shell protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710667.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.824"/>
    <dbReference type="HOGENOM" id="CLU_064903_5_3_0"/>
    <dbReference type="OrthoDB" id="1802372at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020808">
        <property type="entry name" value="Bact_microcomp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01139">
        <property type="entry name" value="BMC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="2">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="93" mass="9391" checksum="92CE3D84BD98A70E" modified="2014-06-11" version="1">MADQQALGMIETKGLVPAIEASDAMVKAANVKLIGKVQVGGGLVTVMVRGDVGAVKAATDAGAAAAERVGELLSVHVIPRPAADVDYLLPTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ01</accession>
    <name>A0A010ZJ01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type metal ion transport system, periplasmic component/surface antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0782</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NlpA lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.834"/>
    <dbReference type="HOGENOM" id="CLU_067080_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004872">
        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30429">
        <property type="entry name" value="PTHR30429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03180">
        <property type="entry name" value="Lipoprotein_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002854">
        <property type="entry name" value="MetQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457939" evidence="5">
        <location>
            <begin position="21"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="258" mass="28256" checksum="FC3DF190FA0065FA" modified="2014-06-11" version="1">MKKVFLAVLALLVISSSACAAEKIVLGVTPFPAKEIADVAKEVLAKQGYELDIKEFTDFVQPNYALEDKSLDANFFQHIPYLENMKSEKKLDIVPLVKVHLLPIGIYSQKIKSLKDVKEKAVVAVPNDPTNGFRAYKLLEREGLLKMKPGNKLTAADIVENPKKLKIRELEAPQLPRTLPDTTISVINMNFAVDAGLDPSKDALALESKDSPYAVVLACRSGDKNSAKIKALAKALNSPEVKKFITEKLGSKGVIPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ25</accession>
    <name>A0A010ZJ25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxaloacetate decarboxylase, gamma chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0802</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710728.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156502_0_0_0"/>
    <dbReference type="OrthoDB" id="2167477at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005899">
        <property type="entry name" value="Na_pump_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04277">
        <property type="entry name" value="OAD_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="130" mass="13045" checksum="259BA181C386AC18" modified="2014-06-11" version="1">MTTGSISSYFVGVPGGLIMSFIAFSIVFIVIVGLMLVMMGMKHVCSAIDNMNKPKPAAPAQSSAAPASAPSAPAAPAAAVSADDELLAVISAAIMAACGSTARVVAFSPVKAPASSAWKNVGRLQNTEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ86</accession>
    <name>A0A010ZJ86_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0858</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710826.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.916"/>
    <dbReference type="HOGENOM" id="CLU_016922_10_3_0"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050155">
        <property type="term" value="F:ornithine(lysine) transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine-oxo-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="PTHR11986:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="397" mass="43572" checksum="647B481BD428FA23" modified="2014-06-11" version="1">MLSTQQIIDKTNKLGAHNYHPKDVVIVEGEGVIVRDPEGREYFDMLSAYSALNFGHRHPEIVAAAKEQLDKVTLTSRAFHNAVLCDFYEKLCGLTGKEMILPMNTGAEAVETALKTARRWGAEVKGVENGKQEIIVCENNFHGRTIAIVSFSTDPDARINYGPYCEGFKIIKYGDAKALEEAITPNTVAFMAEPIQGEAGIITPPKGYLKEVRDICTKHNILFIADEVQTGFARTGRMFACNFEDVEPDIYILGKALGGGVMPISAVAANKDVLGVFTPGTHGSTFGGNPLACAVSIKAMEILVRDDYSKQAEEKGDYFMRRLREIDNPEIIDVRGSGLLIGVEFSVPAAPYVKKLIANGVLAKETHERTIRFAPPIVITYEQIDRAIEGIKKAFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ99</accession>
    <name>A0A010ZJ99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS-domain-containing membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710844.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_9_0_0"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="93"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="158" mass="18145" checksum="9C3F4992C3676F18" modified="2014-06-11" version="1">MKIGELMNKEKVVLHESDTIERAIEMILRHCRTGVPVLSADGRVRGFVSEEDIIKKCLPGYMTTLKNAAFLPDYGQFAKRFAAIRYKLVTEIMQKNVVCFKKDDSDFTVAAEMIRRHFKICPVTDENGFFVGCISRAYLIRSMILEKNRGEKAVLKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJR4</accession>
    <name>A0A010ZJR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fe-S-cluster-containing hydrogenase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_1045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711091.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043374_3_2_0"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011898">
        <property type="entry name" value="PorD_KorD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43724">
        <property type="entry name" value="PTHR43724"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="132" mass="14047" checksum="F470AADEF8386414" modified="2014-06-11" version="1">MKIMQVNAEKCVQCGACIEACSKAYFKENSPELSRVKVANMAGFANINICTQCGACIGVCPTQALERDANGVVQVRKDKCTSCLMCVGFCPSASMFFDGDKQTEPFKCIACGICARKCPTGALELVNVPAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJT4</accession>
    <name>A0A010ZJT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442363.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127486_0_0_0"/>
    <dbReference type="OrthoDB" id="1923013at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458187" evidence="1">
        <location>
            <begin position="25"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="182" mass="20150" checksum="3BC86EAE5A21CD7F" modified="2014-06-11" version="1">MKKSFFAIAALVALTILTAERAFAAPSDNAPDVSELLDARQADVWVEGERLGDLVIGARGAIQMIYVDEQLSRAITADSRLQDWVYDMAQYYGTDATRKKRLFIAHIDVYKPWDFDYTQIFVGDYHLQKGDVLSPSMTNPFGPQPSKSDGFFAFVVPASAAKAGAEIKIGYGDDSETWKVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJX2</accession>
    <name>A0A010ZJX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ORF">Cloev_1117</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711239.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1190"/>
    <dbReference type="HOGENOM" id="CLU_100149_0_1_0"/>
    <dbReference type="OrthoDB" id="1846503at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="162" mass="18744" checksum="1CAAEA15A2DB09CB" modified="2014-06-11" version="1">MIRAVYPGSFDPITNGHLYISERAAALFDELIVAVLVNPEKRSTFSEEERQIMAREALVHLPNVKVKYFNGLLADFMRQQQSRIIIRGLRALSDFEYEFQLAQMNRQLAPEIETFFIVTDAKYSYLSSRAIKDAFQFGGAVRDMVPPGVYRRLRERIPPRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJY2</accession>
    <name>A0A010ZJY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_1127</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442439.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1200"/>
    <dbReference type="HOGENOM" id="CLU_030558_0_1_0"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="5">
        <location>
            <begin position="6"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="317" mass="33885" checksum="A51A27699ABB9321" modified="2014-06-11" version="1">MKYAMIFPGQGAQRPGMGKDIYDRYVSAKRIFDEADEALGFSLSDIIFNGTPEELAHTKITQPAILTVSVAMLRALEQELGTAVEPACMAGHSLGEYTALVAAGSLSLTDGVRLVHKRGGLMQDAVPLGMGSMAAIIGIELSDVSAICAEAAQGEVCQAANINSPTQIVISGHAGAVARAVALIEQKYTAKVVPLRVSAPFHCDLMRPVADRLKEAFKSIEWHEPKFPIIANANARPVQKIPAVREALYNQTFSPVMWSQSVLEMENEGVEGYIELGPGSVLSGLVRKICKGKRPYAVSNSDELMAAAEYLRGANNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL29</accession>
    <name>A0A010ZL29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484761.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_14_2_0"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="241" mass="26424" checksum="497FF71ADA8719EF" modified="2014-06-11" version="1">MRIAVVDDRADERAEIVSLVEEYLARVGVTGAVCREFASAEEFAAALGEQSFDVAALDIIMGEMDGMEAARALREAQPSCAIIFVTSSRDFSIEGYSVHAAGYVLKPVRENSALLFDALAFAASRALRASASMMVKCAVGERHVLLADILTLSKRLLIIYLELKGGETLALSGKYADYEQRLLEDGRFLKIARASLLNADRISAVTREGLLLDTGKEIKLGRRVRERIAAEYARYKVNGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL49</accession>
    <name>A0A010ZL49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cobalt-precorrin-5B C(1)-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.195</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cobalt-precorrin-6A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cbiD</name>
        <name evidence="6" type="ORF">Cloev_0091</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:26285"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:60063"/>
            <dbReference type="ChEBI" id="CHEBI:60064"/>
            <dbReference type="EC" id="2.1.1.195"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CbiD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.195" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.105"/>
    <dbReference type="HOGENOM" id="CLU_041273_1_0_0"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043780">
        <property type="term" value="F:cobalt-precorrin-5B C1-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046140">
        <property type="term" value="P:corrin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00787">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002748">
        <property type="entry name" value="CbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036074">
        <property type="entry name" value="CbiD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35863">
        <property type="entry name" value="PTHR35863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01888">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026782">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111342">
        <property type="entry name" value="SSF111342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00312">
        <property type="entry name" value="cbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 5 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="364" mass="37744" checksum="02992B8879CCF050" modified="2014-06-11" version="1">MASNKGLREGYSTGSCAAAAAKAAAMRALGLPCPESVEITTPEERKFTLPVVGYGDGCCGVIKDAGDDPDSTDGILIKAAVELSPEPGAVLFFAGEGVGTVTLPGLKIAVGEPAINPVPRAMIERAVREVIGARGAKVTISAPLGREVAKRTFNPRLGIVGGISILGTSGRVKPMNEAALLESLTLELNTHAAEGRRAVAVAFAGTGEEALRKAYGIKNRAVVQCGNYIGHLLDESARLGLERLLIGGHPGKLLKVAAGSFNTHNRTGGGAKEALCAQAAIAGASADTVKALYECPTTEEAMRLVREEGLDFLWKILARITAKRCEERAFGDIKSAVAFIDNGGNILGATDDAPAFAEEIRDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLR4</accession>
    <name>A0A010ZLR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multimeric flavodoxin WrbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441468.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.322"/>
    <dbReference type="HOGENOM" id="CLU_050993_3_3_0"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="211" mass="23032" checksum="CD659FBB591E46E2" modified="2014-06-11" version="1">MKVLLVNGSPHEKGCTYTALGETAKTLNEEGIATEVFWIGTKPLSGCVGCKACVKLGRCVFNDCVNDFIARAAEADGFIFGTPVHYAAAGGAMTAFMDRAFYSAFLGGGNRAFYLKPAAAVLSARRAGTTSAFDQINKYFALHEMPIVSSRYWNMVFGAKPEDVLRDEEGLYTMRVLARNMAFLLKCKKAGLAGGVEPPRREEPRFTNFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLW0</accession>
    <name>A0A010ZLW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709012.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.367"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_0"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="262" mass="27918" checksum="9AAD943BAFCCFC47" modified="2014-06-11" version="1">MELGLKDKCALVMASSSGLGKAIAAEMAREGANVMLFSPFAEQLAEAQEDIYKETGRKPAVFTGSITAPGDIKALVKETADKFGPVYALVNNTGGPKPGPFDAFDDAAWQEAYELCLLSYIRTIREVLPQMRENGGGRILCSTSSSVKAVLDNLILSNTFRMGVVGLAKTLSQELGRDNILVNVIAPGRIGTARIDQLDKIRAEKAGISVEELQKKAFAGIPLGRYGKPEEYGKLAAFLCAPSNTFITGQTVLVDGGMVKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM26</accession>
    <name>A0A010ZM26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441577.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_0"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="457"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="839"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="868"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="894"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="939"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="971"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1024" mass="111179" checksum="ED53DF382B025B01" modified="2014-06-11" version="1">MNVIDTSLRRPVTVIISTIAVVVFGLMSYGGMGMQDTPDIDLPVVSVSTTMTGATAAVMDNDVTDVLEEQLNSISGISSLSSASYQGQAVTTIEFDIDRDIDDAAADVRDKVNLALADLPDEAETPTVSKLDVGDSSLVQIAVTGDASYKEKVHYVDKILKTKLQAINGVGEVVTPGMREREIRIWVDPERLRSRGLVTSDITDAVNKKHVELPAGSVILGRSDVDVRVMGEYASVEELKNLAVAVRGGTVIRLADVADVADGFENRENVAQFNDDDTILVGVKKQRGVNEVQLCDDVVSYLHDAEKSLPSGIGLKIIYNQSDFIRRSLSGVTSDVFSAVLLCALLMLFFMQTLRATFVTVITIPVCLIGSFILMRYMGITLNNLSMMGISLAVGMVVDATTVVMENVDRRMKGGLLRYEAAREGANEVSFSVIGGALTTIAVFSPVAFMSGVIGKLFFAFGVTVILTISLSLVLSMTLTPFLCSRILDKGKPGRAARICGMLLSKLERGYRLLLKRAVAHRAATMAVAAGMFVIGMVLVMNTGTQFMADDDESSFMIKCELPSGTEIEESGRVFRELGRAVRRHKAVEYTYANIGTDSGNQSNNGTLYVQLYPKKQRGDINKVMDEVRALTAPFRDVTATFTTFAGKDVEMVLVGGNTATLLDISKKIIAEAEAGGNVRDVETDVRIDKPQLEVEIDRGLADTMDIDVRSMSNELQAYLGGTKAGVYKEDGYRYDIRVMAERAKRSDAADIGKIYFKTGAGDIIQAPGVLSVRKTLAPNVVKRYSRQRSLSISANVTRNFSTGEAAALLTKLAGKYIPRDSGVSLVASGQTKTQQEEFARLFTALVVAIILVYVIMAIQFESFIHPFAIMFTLPLLTPGAFGLLWLSGCKLNMMSYMGLILLVGIVVNNGIILIDFIKQERERCCDKVQAVVRAAPMRLRAILITALSTLIGAIPAALKLSEGSESRQPMSVAIFGGLFTSTLLTLFVVPVVYLILDDVKERACAWARRRLKSNVGRTEEARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMA5</accession>
    <name>A0A010ZMA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441744.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1692427_0_0_0"/>
    <dbReference type="OrthoDB" id="1612055at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="18028" checksum="B20E23C5E9C24961" modified="2014-06-11" version="1">MPEKYLVQRRTASGLETVAELPMLAGDKIDISLLPVVGTMGSAVIESGENANGRYIKWADGTMICTHTYVKEPRYSDFLFLTGEWVLPIANVGTVYKLVVGFGATTNDSPTANHGVYTSIGYQGTETYVWSTGSNSAVKRLADAIRTGGSFGVVSYTAYLVAIGRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMG1</accession>
    <name>A0A010ZMG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Subtilisin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0557</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441814.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_368779_0_0_0"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459165" evidence="7">
        <location>
            <begin position="27"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="173"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="759" mass="79501" checksum="889F1CD80A07BB3B" modified="2014-06-11" version="1">MKNKPFFAAALAAFLAIAVFSCGARAAQQPEYVEGEAIVVMKGTSSSLSGAKSAAARESMKARAAVSASKSGGSVIQLFSPIEESVSGAATSRASSASGGTLIVAHLRAAYGESTEDFIARLTKDPDVISAMPNYLMRRQALKTPNDPLWARQWGPAAAKAPEVWRHGTGTAETVVAVIDSGVIYDHPDLKDDMFVISRELADKMSAESGVISGDFAGSHGAWYHSEVHLGIPSKSYPAIPIGPSPTIPGEIGDIDGGTRETMSRIGDITGHGTHVAGIIGAAGNNETGIAGMNWNVKILPVNVFSYSILGDMAETSDLIRGIDFVLAAKRAGANIRVVNMSFGMWGLPKEMEGSAYDLKIKEMSDNGMLLALAAGNDGEDLDAPKKSWLTKGRRFYPACFKYENTISVGALKKEENGALSPDGSYTNYSVSGKWVDIFAPGTEILSTCRTGKLLGDIFNESGYTSISGTSMASPCVAGAAALLFSLDPSKSAREVKAMLLEGADGSIAKEGYSAYGALDLNGAWEKGFGGTPVTPVSPDIETSGDILPLLAELPEEISQVAGIFTDGQLVTTDEGLYLDFDIVDNALEGLGGREIEEISLLPVFTLADGEMTEGRLCAAAFELDGSDLAAGGTRADLAVFKIKPDGTRLEYKWAANESEYADGRYTILDEDGNAFNGSFDDAAKYTIVLFIKDNGTFDLDGNAGRIVDPTAIAVLKKENSGSGGSGGCAAAGGAASLLAVLIFAVPIVLRRKKESLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZML1</accession>
    <name>A0A010ZML1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484855.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_3_6_0"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="163" mass="18946" checksum="F69B1727A15A9B0E" modified="2014-06-11" version="1">MLKKLWDNLEEYILVYSMMFSVALVFVQVIMRYVFSNSLSWSEELARYLFLWQIWLGASYAVKEHRHLRIEIIQDLIKTRKGKICFELFVMVLWLGFSLFMVYEGSTLTKILFMRGQVSPAMRIPMAYAYASVPVGCALMSVRLCVEIVKSIRCITCENGGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZML7</accession>
    <name>A0A010ZML7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aconitase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710368.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.673"/>
    <dbReference type="HOGENOM" id="CLU_006714_2_3_0"/>
    <dbReference type="OrthoDB" id="363064at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="5">
        <location>
            <begin position="61"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="6">
        <location>
            <begin position="659"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="778" mass="83615" checksum="5DE62B864BD0FB3F" modified="2014-06-11" version="1">MIKLIEKGAYLLNGTVLVEDIEKKGLPAVNEEVRAAGFKPLGWLPEDKVKDSRGTIAAGIIAAHNAAGTEDNYKIRFDSLASHDITYVGIIQTAIASGMKEFPVPYVMTNCHNSLCAVGGTINEDDHLFGLSAAKKFGGEFVPPHLAVIHSYVREMMSGCGRMILGSDSHTRYGALGTMGVGEGGPELVKQLVGRTYDFPRADVVAVYLTGAPRPGVGPQDVALAIIGAVFKNGFVKNKVMEFVGPGIANLPVEFRSGIDVMTTETACWTSVWATDDKVKAYYENHKRPEAFKKLAPSDVAWYDAAIIVELDKIKPMIALPFHPSNIFTIDELNENPRDIFRQVEKDALSKIETPGLSLNLVEKVSDDGCVHVDQGIIAGCSGGVFDNIIAAAQILKGKDVGCGEFSLSVYPGSQPAMLALVKNGAISDLMEAGAVVKTAFCGPCFGAGDTPANHGFSIRHTTRNFPNREGSKPGDGQLASVALMDARSIAATAANGGVLTSAEKYGDLLHETEYSFDSGVYEKKVYHGFGKADASAELIYGPNIRPWPKVYPLAENLMLKIASVITDPVTTTDELIPSGETSSLRSNPIKLAQFALSRKDPKYVGRAHEAQALEDERREAAENKAELSAAAKSVLAHASESDISKIALGSCIFAVKPGDGSAREQAASSQKVLGGQANFAEEYATKRYRSNLINWGMIPFIVDPADRDKFKPGEWLCLPGIRRAVRDGKEETAAWIISEDGHEKSITVKMPGLAPEDREILLAGCLMNYYAEQNAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMY0</accession>
    <name>A0A010ZMY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0730</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441971.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011722_6_2_0"/>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="10">
        <location>
            <begin position="147"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="313"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="345" mass="38980" checksum="0F108AF69EA3BF75" modified="2014-06-11" version="1">MKPQRKKQFLFIYEVMLPVLALFSLFTLVALGAFYFHPEKQPFFIFVVDHIIWAVFAVDFCVRLCFAKSLRDFIAAHISEFVAIIPVFPFIMINYAFELLNWDDTSSLLIQLIFFIKFLAYLGRAYTTQSRFFKTNLLHYAGGVTMVSIVVAALLFSNFERISYGDAIWFSFVTVSTTGYGDIVPHTEAGRVVSVFLMVIGVACISSFTSILAGRIMNSSGPKQSNPHLIAVERQIRRFSLLSEDEVEELCLVLKSLKHHQKISGSDIREKIDAFNAVEDLDLRWRNLPFVKWVRTKFAGIMTDGLEVEASIARKKDDGAGAVPPDAPAAEDKKEAPAKPREPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN14</accession>
    <name>A0A010ZN14_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cas2</name>
        <name evidence="10" type="ORF">Cloev_0760</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442012.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.812"/>
    <dbReference type="HOGENOM" id="CLU_161124_0_1_0"/>
    <dbReference type="OrthoDB" id="1951170at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09725">
        <property type="entry name" value="Cas2_I_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34405">
        <property type="entry name" value="PTHR34405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="87" mass="10243" checksum="5A9CA5972793260E" modified="2014-06-11" version="1">MFVIMFYDVGEKRVNKVLKTARKYLTWIQNSVLEGELTPATLEALKVDVKNIIDNEYDSVLFYVWRTERYMTRDTIGIKRGSVDSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNK1</accession>
    <name>A0A010ZNK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system methyltransferase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442209.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1007"/>
    <dbReference type="HOGENOM" id="CLU_015410_2_1_0"/>
    <dbReference type="OrthoDB" id="791672at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="277"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="604" mass="68610" checksum="044AC15B077236B3" modified="2014-06-11" version="1">MKRADIITTVGRDFLVDNIENSEFSYEKALKEIGKDYLNFLASGALRRYKNLDLRFANDRVTVLIETKTKLIKGNATKDIEQLQQYVIYEKQLTDNKVIAILAATQTDEIRVWLDDSGIIDDEHENKSERVIRPFTDYVDVFFGAKNDKRTIVENTYALNELLHGYGINEKIRSQFVGTCLLALKNGLKYEGLSTKQIRAGIEEILNALLDKAKDLNKAAKLVILKSKVIDSQDVTDLTKEQFSHVLQEIKDKILPFINDRTTKGQDLLNLFFTTFNKYVGKADKNQAFTPDHIVHFMCKVVGVNRNSVILDPCCGSGAFLVRAMTEALADCDTEDEKERVRKKHIYGIEYEETAFGLATTNMLIHSDGNSNIVQGSCFRVDNYVDAGVNVVLMNPPYNAQRKHSDETYVKTWNSKIKEDPSKGFHYVYKIAEKVKIGRLAVLLPMQCAIGTDADIKLYKTKMLEEHTLDAVFSFPSDMFHPGANANACCMVFTLGTRHENAPTSTFFGYFRDDGFVKRKNLGRIEKTDDKGLGVWANIEANWLDLYRERKAEPGLSVCQKVTANDEWLAEAYMSTNYSTLTQGDFERVVRDYLAYVLKNGEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNL1</accession>
    <name>A0A010ZNL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442250.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1027"/>
    <dbReference type="HOGENOM" id="CLU_004785_2_0_0"/>
    <dbReference type="OrthoDB" id="1143316at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="3">
        <location>
            <begin position="5"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="850"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="258"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="340"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="447"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1103" mass="120634" checksum="DA1493B5CFFA1163" modified="2014-06-11" version="1">MRPLKLTLCAFGPYSGKTVIEMDRLGESGLYLICGDTGAGKTTIFDAITYALYGSASGEIRETEAFRSKYAEASALTFVELEFLYDGKRYTVKRNPAYLRPKQKGSGFTKVAANAELYLPGGGVCCGFRPVSDRIKELTGLDRAQFSQISMIAQGEFLKLLLASTDERGALFSRILKTEYYRKLQDKLKEEAAARERACTELGGAIAQYMDGVETPEDEELREALKRAKGSPPEEALALVRELLRLDGDTDDKLSSELRETEEALAALGAGLVRAEEAEKTRKNLTAAKADLTEREKELTLLTEENSSEEQKETRRLALAHEIESIRDELPACDELAARRAKLEAIKSAISKDKEEIERRQAALATQAASTESLKAERAGLKEAAAEKAALEAALEAARSRSAVLAAILSSAGRLKSMKRELLDAKEAKEKSLGKYAEEERSGNERLRAVREDEARAKNEAAALREADLTFERLKNSRQESGERARRLREIEERLAEQDAALKKLALARKGFAEAESRYETARDSYEDKNRLFLNAQAGILASALEEGHPCPVCGSRDHPSPASLAGEVPTERELKEAAKNKGAAEEKYRSLSALAGGLESEAREKRGVTARLAEEILGETSADKILPALEAKRYENKTLLISLDEALTAAAKDIKNRNESEQKAAAFAQEIKMREEELCLLAEEWRQAQAEADNGISRLAGMIEADERSLTEDCGKVLAECGLDKAEAQSAAELKEAEKTVCETKRAIALAAAKIERTRELETLIPAGEEQRNTLEQAIRSAEIKLTEAAGALRAEEDSVQALSLRLPYAGRAEAERAVKEKEKELESMKAALARSRLALQGCRTKRDEAEGRVKGLEKGLSGAEETDAEELKKEQAAASARKEALALERGVVAARLSVNHKAAAGLSAKSKELAEEEKLRRLLKPLAETANGTLNGKPRIMLETYVQMACFERILQRANVRFMVMSSGQYELKRRENEETLKGKIGLDLDVVDHYNGTVRGVKTLSGGESFMASLSLALGLSDEIQSVAGGVKLDTLFVDEGFGSLDGESLEQALKVLASLSEGRRLVGIISHVGELRERIEKQIVVTKNGASGSEAEIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNM4</accession>
    <name>A0A010ZNM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442269.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1037"/>
    <dbReference type="HOGENOM" id="CLU_091350_1_0_0"/>
    <dbReference type="OrthoDB" id="1169851at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014997">
        <property type="entry name" value="DUF1847"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08901">
        <property type="entry name" value="DUF1847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="194" mass="21310" checksum="7FBA807E3268DE55" modified="2014-06-11" version="1">MRCDLCTEKLCKEGMACTSCDAAALYSDTEDRRMMRAASEVEAEYYGEVNRIQEIILFSRKMGYRKLGLAFCAALSEEAAKLSQILENYFEIATVNCKVCGVPKAEMGAMESDKVGSISCNPIEQAEVLNAAKTDLNLLLGLCVGHDALFIKYSQAPVVPVAAKDRAIAHNPLGALYCSAIFKRMMKEAKNQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNQ5</accession>
    <name>A0A010ZNQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L30, bacterial/organelle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0997</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711014.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131047_2_1_0"/>
    <dbReference type="OrthoDB" id="2084745at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="5">
        <location>
            <begin position="4"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="60" mass="6977" checksum="486ACAD0DA12A620" modified="2014-06-11" version="1">MAKLRITWKKSTIGRPPSQERIIKALGLHRLNETVYHNDSPQIRGMVNKIGHLLEWSVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNQ8</accession>
    <name>A0A010ZNQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711019.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168121_1_2_0"/>
    <dbReference type="OrthoDB" id="1979791at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06088">
        <property type="entry name" value="KOW_RPL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041985">
        <property type="entry name" value="RPL14_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="114" mass="12549" checksum="ABCC961DE49106F1" modified="2014-06-11" version="1">MGINSSAYKEGFRTGDIVIVRRGKYAGKPFAVMGASDDRILIANGAEYTAARPKKKNVIHLQQTHYNLEDVAGRVAGGKPLDNGWLMQKISKVLENSGTSCKQEDEAAEWPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZP08</accession>
    <name>A0A010ZP08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ORF">Cloev_1125</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711257.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1198"/>
    <dbReference type="HOGENOM" id="CLU_039592_3_1_0"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="112"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="233"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="250"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="322" mass="34809" checksum="57DDB930AD2CB507" modified="2014-06-11" version="1">MAMINGYPVKIAGTGKYIPEKIMTNFDFEGFLETSDEWIRSRTGIKKRHIAADDEKCSDLAYRAGLAALEDAGMRPEELDLVIVSTNTPDTYCPCTSAKVQGKLGAKNAGAYDILAGCTGSLTAMLTAIGGIAGGIWNNVLVIGAEDFASVLDWNDRSTCILFGDGAGACILTRSAEGGPRFISGELMADGDKYDFITIDKEEGHPSPVLRMKGSEVFRFVNTYLPPFLKNFCEKSGVTPPEVDFWVLHQANTRIIDSLFKRLGVSTDRTLINLENYGNTSAASMVVTLDEAMKEGRVKSGEKIMFTAFGAGMTLGALLYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A792</accession>
    <name>A0A011A792_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441203.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1955785_0_0_0"/>
    <dbReference type="OrthoDB" id="1977671at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459426" evidence="1">
        <location>
            <begin position="26"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="128" mass="13693" checksum="37610F354629ED53" modified="2014-06-11" version="1">MRRKIFILLAAALISAFMAAGTLYAAECSGGGAPLEIVNKSGREITGLFLSQTGRESWSPNRLSGPLAAGASASCDIGRDGILGLSDLKLTLKEGGEIIWRRLPILEIFSITADDKLEPRYERIKLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7C1</accession>
    <name>A0A011A7C1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_8_4_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="219" mass="24979" checksum="2E6CEED58EBD54B4" modified="2014-06-11" version="1">MKWARGPERVKVMAEKRRVYLMRHAKPELPMNGRVYYGQTDYPLSAQGIAAAEEVGEYLKGKITFDYLYASDMIRAQQTARLVAPYLPITTVPALREVNLGEWEGRGYDEVREQFREIYEARGVKFAEVAPPGGETFGELQRRTVPAFEEILSARRSGAILIVAHGAAIWSIMARCFGLDLNDMFFFSQDYCGIHVLEPANGRMRMYQYNWLPLLKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7G7</accession>
    <name>A0A011A7G7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Fe3+-hydroxamate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484765.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_2_5_0"/>
    <dbReference type="OrthoDB" id="1473468at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458570" evidence="1">
        <location>
            <begin position="23"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="26"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="283" mass="30284" checksum="5F9192E9338EC756" modified="2014-06-11" version="1">MAPRIILYVLIIFLLSPFQAEAAAKRIVSLYPGHTDNIVALGGEKRLVAVSKNDDDDMLPDLPRFSAKSGAEEILALKPDLVLTRGLAERQNPQLRGVLERAGVRVVSLEPPRWDDFAAYLRELAALTGSDPAAGESKLKKLRGAIAAEAAKKSKGKSPAVFVEATAKELHTCSPDSWAAKLVELAGGRNAASDAQPVRKGSAIAPYGLERILKAAAAGEIDVYLVQQGTMNAADKESLAARPWYPAIKKIKTAVVPEGELSRPSLLGLEAGGRRLIKIFYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7I6</accession>
    <name>A0A011A7I6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe2+ transport system protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709195.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150646_6_0_0"/>
    <dbReference type="OrthoDB" id="2047422at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="70" mass="7593" checksum="3FCBDFC3ECEC47B8" modified="2014-06-11" version="1">MMPLMMADTRMAYGIKRIGGEGTQRQFIEGLGFVPGAEVVIISKNADNLIVSIKGSRVAINRDVALKIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7K3</accession>
    <name>A0A011A7K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0139</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.150"/>
    <dbReference type="HOGENOM" id="CLU_016950_9_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="8"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="155"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="258"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="391"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="462" mass="50985" checksum="8B1D179A3CC58110" modified="2014-06-11" version="1">MSFVPAHIFREYDIRGIADSELTDEHVFLIGRAFGTWLSRRGVTETTVGGDARLSTARIKAAAARGLNAAGVNVTDIGLVSTPTFYWSLYRFEAGGGIMVTGSHNPKEFNGLKVAYDRATLWGDDIQSIYRMITADDMTAAERPGVYRTADISAEYIDMLVSKITLGPRRPKIVCDSGNGTGGLYAPEFLRRIGCDVTELYSTPDGRFPNHHPDPTKRENLPALIAAVKEGGADFGVGFDGDSDRIGVVDNDGEVIWGDRLMALYWSEILPKHPGAVAICEVKSSMALPETVEKLGGRPMWWNAGHSLVKAKMREEHALFSGEVSGHMFFADEYFGYDDAFYAAGRLARIISNTEKTLAELMRDIPLYPSTIETRYDCPDDVKFGVVERVKEAALAEKLNTITVDGVRIIYKDGWGLVRVSNTQPVLVARCEGRTKEALDEITKDMKRRLLAAGSPDFEWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8E6</accession>
    <name>A0A011A8E6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441570.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_464480_0_0_0"/>
    <dbReference type="OrthoDB" id="528536at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="601" mass="67673" checksum="A347DCC3AEEA03A0" modified="2014-06-11" version="1">MLFHEKLSLLKEAIAATSSALARSSGLDASCVCRYLGAKHKPPRYGKTVAYLAAGAAKLAENGDRVGELRKLVGAHREEVLHDAVARWLNADDSSLREKKRPEPQASLRGRKKKQRAGTAQKFSLLMEAFKTSNAAVARYVNVDSSSISRYRSGRRGMGTDDPILRDICRYFAFLCRSHGIPKELSEELRVPADEAADEEYITAKLFEWFRESGSAAPTRLLLQGIDSAEPRGLSSNEKNGKDAQAEGVKFTEEIFRGADGVYSAFLKFTETILAAKEPADIRVCASDFSWFARSPRFRGGWTALMREILSRGHRIKVIHDLNLDADEMFCAASSWIPLYISGQVEPYYLTRPNRSLFSEYIGAAEGLCSMRFSCFKGKEEEVTAFFSKSPDKAAFVSEQFGNLLACAKPLVKTYGIGDLKELHRDIEDKRSAPGGDVVKFMHRLSPESMPEHLARRIFDRAAASEDERDELMKYYRARRKAFMSSLSEVSVIEVYPEYSAADIEAGRVGIHTPWTLGDRELRYTPEEFREHMRAVGLLAQERSNYRCVTNADFPFRNIDIVSKEGGATYVIKNEAPLVAFSFLHSYMNYVIDRYLRRYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8F4</accession>
    <name>A0A011A8F4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441581.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031290_0_0_0"/>
    <dbReference type="OrthoDB" id="1395299at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458290" evidence="1">
        <location>
            <begin position="24"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="438" mass="47364" checksum="E7FA0EFE692FD72F" modified="2014-06-11" version="1">MHKKFTALLLALCLLAISLPARADLLFTRQDNSYANTALGIIQGSGVPVSPLVSNMGGNAGQGIYPFKNADGYFRVAVTLYTSNGTDVISIYNPGEQSQWTQPSAWKAPLREATTTLHNTRTMVELNGNLYATAYDIPIVSRVTTAGDVYKQDKKYEYYHNDSKYDGHGEGLCAYNGSLYAIFTGANDPWDTEHGSYRANCLVKLDADLNEVTSVDMKGRNLDGFTPGAYSQKDGMLYVATLGGVQLFGDKWNTGSCIEAANLATMEVKSLITAEEMNAKDPTFKHMFDAVAFAGDKVYVQAAKWTAGEDYSSGYSIRVYETTLEKLQKGDLGTLLKDFNGDYGYRLGLVYDEKTGYLWAGVGYSLWRYDGSSWTEFGSNALSGNISAYTAVNPIGTITPEDPDTPSGDGGGSGGCSAGYGLLALLAIVPAALRRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8F7</accession>
    <name>A0A011A8F7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane receptor for ferrienterochelin and colicins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0393</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.434"/>
    <dbReference type="HOGENOM" id="CLU_008287_18_5_0"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458431" evidence="5">
        <location>
            <begin position="24"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="48"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="181"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="658" mass="73082" checksum="94F4789E770ADB53" modified="2014-06-11" version="1">MRKSFIAIALLSLLCLTPGGAGAAERPAELPAEKITADAGEEDKLLLSPGTVTVIKPQEMKGEQKNLPELLKQVPGLHIIETKGRGAYTTASVRGSSASQVSVYVDGVLMNLGSEPAVDLTTIPVENVERIEVYRGYIPARFGGASMGGVINIITKKPEKAGGSVTMGVGSFGRFTGGATYNSPLGGGAFMASVNFDRTDGDFEYLNDNNTPYTPGDDYNANRQNNGYKNSNVLLKWNNDNWKIEGGWKRNDRELPYSAPGADKADSVAGATQVTDQWNMIVSRRQKLGDLDLGLRLEYLNQTKDYDDPSDVIGGWGEQHNKYETKRFGTAVDGSLPVGDRHLVEFLWNYYNEELHTTGDIVQKFSGRENHTRNSWNGQIQDTISLNKAGDFWLTPIVRWNSAEGVTEFSWGAALTKKFGKGWTAKVTGGTYNRAPNLYELYGDGAFIIPNTGLEWEDGTQYDAGISWEGELSKAQVKAELTYFYRKSNNLIDYLMVNPRYAQYVNIGDAEVSGIELEATVKRDKWDVYLSATWMDATNKTPGYMYDTPLPNRPEWEGLLRVSRKILKDDRATLFAELHHIGKNYYDMQGEVGWDNLTTVGFGVRYLIRENLKLVVGVDDIFNAGPDVLLFATGNGPERTLWYPIQGRAFYATLMWTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8G5</accession>
    <name>A0A011A8G5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ORF">Cloev_0403</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709100.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.446"/>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_0"/>
    <dbReference type="OrthoDB" id="43416at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="285"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="457"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="608" mass="67324" checksum="DC21950AD61EB9A2" modified="2014-06-11" version="1">MCGIMGYIGDRDTTKVILEGLAKHEYRGYDSAGIAVIKDNKISELRTIGRVSQLAERVAKEHFTGDFGIGHTRWATHGGVTENNAHPHVSSDHRVVLVHNGIIENAREIRADLEAHGIKFHTETDTESAVQYLGYVYDGDPKAAIVKLTKRIRGAFALVIMFYDKPNEIWVARKGSPLVVGRAENEGFCASDPTALLEYTRDVWFMDDDEMAQITKEGCKFFDFSGAEHDKASMHLDWDAAMTNRGAYPHFMLKEIHEQPEVVAHTLLGRVAGESVDLSKELGWTAEEAAKWKKIHFIACGTSHYATVVAARIMETLGRFEIRTEVASEYRYRNIPIDDETLAVFVSQSGETADTLHAARLAKEHGAKCLVITNVRGSTIHREVGEALVTPAGPEIGVAATKTFMAQMTVLTLLGLYLAKLRGDLKPETEKRLTSALMDIPGKLATVLSHEKDIEALARDFADARGFFFIGRGLAYPPALEGALKLKEISYLHAEAYPAGEMKHGPIALLDKELPVVALVPKNDLWEKTISNIEESMARKSPIIAIATEGDGEIGHYTKHVIFTPETEPELFPFVAIIPLQLFAYYIARQRGCDIDMPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8Q9</accession>
    <name>A0A011A8Q9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent phosphoesterase, PHP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709627.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.557"/>
    <dbReference type="HOGENOM" id="CLU_067347_1_0_0"/>
    <dbReference type="OrthoDB" id="1309717at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="274" mass="29610" checksum="7CFC3AF3D5A570E5" modified="2014-06-11" version="1">MILIDMHVHSCYSDGTFTPEQLVSAARRRGLSLLSLTDHDTTAGLGPLMRACAKEGIKGLCGIELSAEAPFTLHILGYRISPGAGRLEGRLDYIRGRRDARNLMMCEKLRALGLGVTIEEVREISGGEVVARPHIARLLINKGYVGSVAEAFAKYLARGAAAYVSRERLSAEECISLIREAGGVAVLAHPFQCRLDDDGLAALLCRLRDAGLWGMEAIYGANSPETTYRHLKMAGRFGLYTTAGSDFHGGNSPGIELGMPVSDDILPWARLGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8S7</accession>
    <name>A0A011A8S7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441791.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.579"/>
    <dbReference type="HOGENOM" id="CLU_069356_15_11_0"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="191" mass="21547" checksum="2750453A3945F594" modified="2014-06-11" version="1">MYAEERDTSKRILEAALDLISQRGYANVSMRDIARQAGVAISQIAYHYKNKEGLFIALIRQVKESFLGDIQEKMSRISTSDEFIDFLCEYSKESIVRDSDIHRLRLEFSNLAMGPGPFRAEFSTLVGELLDIVASYVSDYAPHLEILKTHSPRQVANFIIALILGVSTQYLAEGKDKRALETIDILKAAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8T2</accession>
    <name>A0A011A8T2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709662.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012817_10_6_0"/>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458437" evidence="2">
        <location>
            <begin position="22"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="456" mass="48072" checksum="9E1D64AC467B5470" modified="2014-06-11" version="1">MLTRKIIMAFLIISFAAGAVAAAPAPMPSAAPRSADMAPAVDDAALAALLVKAAANNPQIAAAAQKTAAAEAQVSQAQAKMGPKASAGMGALWMRDGISKNADIPGMGMLNVPILGSHTYAAAVGLTQVIYAGGSLTAQKQAAQLARDAAAAQERRTAQSVENAVCRAYYTLRCAQAKELVAEEAVSLSKSHMAQAEKLLKAGVVAKNDVLRSKVAVASAELDLIRAQNGSAVAFTALRRAVGADLPDGLAETRPLNKILTAAEGQPPYGEAKGAAELAMERREELKVYALLSGQAEKLARAAQGQMLPQILGAVGYFAADDKFFPSEQSEPAAAVGLYWNFYDSGEMRAKTNEAKAKAKELLFMLDDMKNAIRMEVTQADLNLKSAHSRLVVAARQAGEAREDYRIATRRYAESVGTNLDTLDARLALTNSLTELATAMYDIKMAEADLRYAIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8Z2</accession>
    <name>A0A011A8Z2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic component of amino acid ABC-type transporter/signal transduction system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_532877_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="65"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="511" mass="58129" checksum="ECFDFAA18DC6E1BE" modified="2014-06-11" version="1">MFDAAPEDQGADAINMPPTKKNFQKAYKYLPVSACLFRSLSVILAVLLAAFFCAFPSDASQGVRKVRVGWFERNGYMEKAEDGSYYGYNYDYLRNISRYTGWRYEFVEGSFSSLYEALKRGEIDILGCVFYTKERVAEVGFPGTDAGVDYLSLFTAAKSRLAENDFSEFDGMRVGVDSDENRRRLLEFAKNNKFTVRPVNYRSLSEIQRGILRGDIDAGLTVGLGNNEKFRILSRFAPQPFYFAAAPGRNDLRAGLETALTQIKIQNPLYEKELSEKHIFRSSRYITFTREEQEYIKRAGKIKVAYDPNWLPYEFTDKDGKYRGITSDVFERISAVTGLDFVYCPADSPQAADADLISCFDHDYDEAEKHGLLMTDIYMRVPLMLVRRSDKVFDSTKDTVTVAPESLRASGKKLEKEGYLLRYCRTSGQCLEEVVKDNDVDQTLLSSFSAEILLDESRYRGLFGVVLQGYWFNACIALTDDGNAMLHDIINKAVLYISDQEVDNIVIRHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A918</accession>
    <name>A0A011A918_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441893.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022238_3_1_0"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="359"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="604" mass="69740" checksum="1CFCE3269DA2B0E4" modified="2014-06-11" version="1">MQNITKRSQNDYIFQNNTRLYFRQSIPPDLRPIFKKTEIRISLRTPDKRLAKRKAAVLSSHIWDIMTALRKGDKRMTELSTEQIYQLVKTWVDKELADDEAGRALSVVNGKTTISNEEMIGYANEMHSTIQSDCREALATENYSYGSPGAESIIEDNDLSISPDSQEYKALCREVIKAQYELCNVMKQRNSGKYPETYTSTAVNPVLYNQNVKQSNVQKKQQNKFSTAFQEYVAEKKLKGNWTPKTVLDATAKVNIFIEIIGDIKLCDITQEKMKEAERLILKYPSSRTKKKQYKDIPYSQLKKMDIPETDRFSHKSIENYMIQVNGFLKWLKPMYEMPEWLPVIMSAPKADVTQDTTASKDIWTTEELRKIFNDPAYIQGEKTTSTSNTRKKYTGAIFWLPLMALYSGARPEELCGLYLSDFKVIDEVKCYQLTPCIEDEEGNLVKAKRIKNTASRRIVPIHDELLKLGLWEYVQELKEQGHARLFDELAASGADQRYSTGYTKWFNRYVSQTLLIKGSKQKGAKVFYSFRHTFINYCVQNSLRDIYFERVVGHAVQGNESTLKHYAKPISPRILKAEVIDRVNFDVDLSSLKNNPFSRSMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9G7</accession>
    <name>A0A011A9G7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710722.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.850"/>
    <dbReference type="HOGENOM" id="CLU_128233_0_0_0"/>
    <dbReference type="OrthoDB" id="1335734at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="137" mass="14683" checksum="98E7F4B2B013192C" modified="2014-06-11" version="1">MDRKIRVVVAKPGLDGHDRGAKVIARAFRDAGMEVIYTGLRQTPEQIVATAIQEDADAIGISILSGAHEYCFKAIIDLLKEKNAEDIIVFGGGVIPETDYPTLLGFGAGAIFGPGTPTSETIEWLEKAVAEKRAKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9X1</accession>
    <name>A0A011A9X1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0946</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442222.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1015"/>
    <dbReference type="HOGENOM" id="CLU_098588_2_0_0"/>
    <dbReference type="OrthoDB" id="1627779at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase_C" evidence="3">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="187" mass="19949" checksum="59BA5C20DC6956C3" modified="2014-06-11" version="1">MNEIKHIKLPLSDEDAQALRAGDIVRLSGSILVGRDAAHKRMAEAIREGGEPPFPIENEIIYYAGPAPTPPGAVIGPVGPTTSGRMDPYTPLLLSRGLRGMIGKGKRTPEVLAAIREHKAVYFGATGGTAVLLADSVKHAERVAYEDLGPEAVLRLTVEEMPLVVLADCRGGDLYVSGPEEARKSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA23</accession>
    <name>A0A011AA23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type cobalt transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442300.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1080"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="283" mass="30370" checksum="D769B0D7925F1C4C" modified="2014-06-11" version="1">MPLIVKELSYTYNIGLPTEHPALHGVSFEAQAGEIVSVLGHTGSGKSTLAQHLNALMIPQKGTVVVDGVNTAEAPREVRRKVGLVFQYPEEQIFAETVADEIAFAPRNWGAGEDEIKEIIPEAIRAVGLDEKILAASPYNISGGQKRRVAIASVIAARPAYLVLDEPTAGLDGRASLELIKTLKDFAQKGMGIVHITHDIELALDISAKILVLEDGRALSWAAPAETAALICAEKIKGLAMPEILELAKRLKEAGKIEALTWSPDRLADELVSAAGIRGSRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA42</accession>
    <name>A0A011AA42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein required for formate dehydrogenase activity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484901.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056887_4_2_0"/>
    <dbReference type="OrthoDB" id="948173at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="239" mass="25243" checksum="7EEE29F43CB39BA2" modified="2014-06-11" version="1">MESAVRQIKIIRVGPDGTGTAADDELISEKTVSLYVDGRYDHAAVITGGGEKLWAAGNLKCRGLISSADDIEDISVNGNIIGVRLKRRRVPLKPAPLSVEWQVGPELVRQKIAELAQAKLYLRTGCLHVALLSSNRGETLFSAEDVGRRNAVDKAAGWLLYEGADPAASLLFISGRMPGDMVLKAANAGIPFIASVSAPTADGVAAARAANITMIGFARGGGFNIYSADGRVELAEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA56</accession>
    <name>A0A011AA56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4236 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_512595_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025330">
        <property type="entry name" value="DUF4236"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14020">
        <property type="entry name" value="DUF4236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4236" evidence="2">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="531" mass="60565" checksum="86470C4509578328" modified="2014-06-11" version="1">MGIRFRKYITIIPGVKINLSKSGVSATIGHKGASVNISKNGTFVNAGIPGTGIFMRERISETRTGKTRTIPSVADITETMHEEADRLNEKVAKDLVIWEHLPHPMQYPVFQIAPFYLEKPRPIPVPMLPIFVGVVITIIIFVLANLYTNSTEWAVVASAIPACVGMFFSFKQKAQIDYQNSTKWQSEYDKWDAEQKNLEEDFVAIIDCGKEEPEEALSVAFENIRWPYDTHISYQVDNDVALVDIDLPEIEELPDSVYVVRGQGRDKEIDTKAKTKVKLYEEYARHIHGIGVVVAATVFSTLLHVNTIVLSAFSQRKSKQTAMTIDEYLYSAIITRDQWTSLFDSSRSWMYDDPIDRLEYFDIRRNMSSSYIFKPIKPFAGDDINGTVNCINARYGFRNYRWGCPSSDLEERKEYDNERPYIKIYEKTKENLQLGDIALLKIFYIFCLDRLMAVEIQSGLVNYENISQLLTHGLGEAEAGNSNLEELKWLNDKSLLLLSKTDEAVILNISSHTEIDLMDKIDKKERGELPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA85</accession>
    <name>A0A011AA85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methenyl tetrahydrofolate cyclohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442395.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1155"/>
    <dbReference type="HOGENOM" id="CLU_088419_0_1_0"/>
    <dbReference type="OrthoDB" id="1965647at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FTCD_C" evidence="1">
        <location>
            <begin position="10"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="207" mass="22261" checksum="21AF2971E63A259A" modified="2014-06-11" version="1">MSGKLVEKSCVEFAEALASKMPTPGGGGAAALCGALGTALCSMVGNFTTGRKKYAAVEEDIKVILSKAEKIRQRFLELADEDAAAFEPLAKAYSIPKEDPKREEILERATLDACRAPLEMMHYSCMAVGLLDEMKEKGSVMLMSDVACGALFCKAALESAAVNVFVNTKTLRNRERAAELESDADDMLRLYSPKAQKIADEIAGGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCI7</accession>
    <name>A0A010YCI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate synthase/pyruvate phosphate dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441231.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015408_0_0_0"/>
    <dbReference type="OrthoDB" id="218209at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="1">
        <location>
            <begin position="27"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="575" mass="65820" checksum="5F260E508902F974" modified="2014-06-11" version="1">MNYGDFYRSFDPAPFYEERGWLIGDGRIGGKAKGLSFAHHILEKNGLLEDVHLPKYSFVITTSVFDEFMEQNNLWERLMNLRAHSDAPELYKICEAASLPPSLDGPIEKILDLIEVPISVRSSSTLEDDVNLSFAGKYATRFSSNAGSREERRAELVRAIKIVYASTYNPAAREYKRKHGIQWGGERMAVLIQPIEGRRYGNMFYPELAGAAFSKVFRRPSPRIRKEDGVVRICFGLGTRTVDRAYARTFYLTNPNLRPEGTKPHEIVTHSQEHYDYVDIEHRKFTSQHISVTIKDILKKHRMAPTYLQWFDDNAFHWIHTDPSNMNAPRPVFTFSELPSRCPKLFTRLKKLLSLFEEELQLPVDMEFAYEVSDDRFTLVQLRPLSVYDDKGRVEIPDTPPRKTILRGDRMVANGRLECTRHIVFVDPDIYGKQADFADIARAVGEINDRLDGERYILVGPGRWGSSNPLLGVPVRYNELSNSGCLVELGIPQKGMAPELSYGTHFFLDLDGDNILYLPVFDGVKNNVYNREWFESHPWQTISHPAVRHYEGCFDVLLDGDTETGIVIDKTPEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD01</accession>
    <name>A0A010YD01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative permease, DMT superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082650_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="117"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="260" mass="27308" checksum="A8176E60F0AC9832" modified="2014-06-11" version="1">MSLMRSCGGLVCAVGLVSLVQGANVEQLGASEALVFIALVLCNNVIGDVFLFFALHRLGVARGSAIASSYPILVAFASHLFFGSPLTPAIVTGTLLVVAGVALLCRTGRDEGKLSASGLVYASLASVFWAAGLLFNNELLVEGLTPATVVLGRGVTFFSIAFLIWFFRLLTVKRDLDGWRVFLKRDSLYGLLAGACSLGFGAWFYSSALEYVSPAVATPIGASNPIIASVLAMLVYKERLRPAQWAGIALAVGGSILVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD49</accession>
    <name>A0A010YD49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093674_4_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34980">
        <property type="entry name" value="PTHR34980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="114" mass="13015" checksum="B8E9580516F1FCC7" modified="2014-06-11" version="1">MEDFIYSYKKMFANYFVFEGRTPRSDYWQAFAVNIVVGAVLVTLSRLLPMLGILNYIYGIAAVVPVLTMTVRRLHDTDKSGWWALAAFFPVLNIVLVAYCCLAEASRGRNRFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD66</accession>
    <name>A0A010YD66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="205" mass="23657" checksum="2D4D049967BBCD2D" modified="2014-06-11" version="1">MRRTKKEADETRRQILETATDMFIENGFSNTSLTDISHKIGMTKGAVYWHFKNKDDVLLQIVKKNCSLIIQDAVNSLVDPESGDTIFSFYKKVLERPASDKRYAKFHSLMRQNHDWPEDVRPAVFAIFDETLQTERKLVENYITRAQTDGMMRADIEAEKVAVVIASIINGLCMLQTKELLPPEFLKYDRLLFESFSQTLASLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDM2</accession>
    <name>A0A010YDM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441576.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.421"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_0"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd08179">
        <property type="entry name" value="NADPH_BDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034802">
        <property type="entry name" value="NADPH_BDH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="7"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="404" mass="43949" checksum="70163A141A6A4BBB" modified="2014-06-11" version="1">MARFTLPRDLYHGKGSLEALKTLKGTKAIVVVGGGSMKRFGFLDRVEQYLKEAGMEVRLFEGVEPDPSVETVMRGAAVMREFQPDWIVSIGGGSPIDAAKAMWAFYEYPDTTFEALCIPFNFPTLRQKAKFCAIPSTSGTATEVTAFSVITDYAKGIKYPLADFNITPDVAIVDPELAETMPKKLTAHTGMDAMTHAIEAYVSTLNCDYTDPLALHAIEMVSENLVKSYNGDMAARDRMHDAQCLAGMAFSNALLGIVHSMAHKTGAAYSGGHIVHGCANAMYLPKVIRFNAAEPAAAERYAKIAKYLHLEGKTTAELVEALVDHINGLNAQLDIPTRIKDYEGGIIDEKEFMEKLPKVAELAVGDACTGSNPRAITPKQMEELLKSCYFDKEAVKAAKSTQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDT9</accession>
    <name>A0A010YDT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441710.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_801013_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="346" mass="37600" checksum="B7DD1F0D05C3A8F2" modified="2014-06-11" version="1">MRRLLNLRFFDGTAGYGEMSDEDFQNVMDSVRYAGFDEDDPAPVPVPADDDAGNGDDSGGGESTPVQNEPPAAPAAEPEVPPAQPEPPAQQSGIPPHLADRYAPIIDALETDPSFRQALADAIAARRSSAYVPAAAPQPEQAAKPADEDVEPVCGEDELLEDFERRHGEWERRQQDKRVRAEVEKALSERQEAFQREQFIRRSQTVNELVQQDTEAPAVASFIQKNPAPARLMQLMNEDPDVFMYVYDGMRQIVGKGNYFKEIAMRQRGVPTTQPAAAPSQSAAQPSAVRSPAAVPVRTHVKTPQAPFTENGGVSSKGGGGGGVSFAEMSDKEFASYMKRVSMQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDW2</accession>
    <name>A0A010YDW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucyl aminopeptidase (Aminopeptidase T)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.546"/>
    <dbReference type="HOGENOM" id="CLU_062630_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="324" mass="34669" checksum="E2F54E6366429615" modified="2014-06-11" version="1">MEMKEALMMQGARTIMDNCVSLRAGETVLIVTDMVQEKIAKVLSAAAVERGAEVIVSIMKPRKRAGEEPPKIIAESMKHADVVLIPVSYSVTHTFAVKEAAESGARLLVLTDFTEEMLISGGIEADFRSIKPICKGVADAFTKGSKVHVTTPGGTDLWLDITGRRGNALYCVVEPGEFSTIPTVEANSSPVEGSANGRIVADASIPYLGIGVLDEPVVVDVKDGFITDIRGGRQAEVLKRDLASHNDPNCYNIAELGVGLNPKCRLCGIMLEDEGVISTAHIGIGTSITLGGVVKAPTHYDLLMWNPRIEVDGRVIVDGNEIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE64</accession>
    <name>A0A010YE64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441873.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.671"/>
    <dbReference type="HOGENOM" id="CLU_034178_1_1_0"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="11"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="335" mass="36362" checksum="BE237BC13677D39D" modified="2014-06-11" version="1">MRRDAVNVSGIMVCGEVRRGTIHSVTMELTGKARELADKKNAKVSCLLFSRDLNDDPALLFRFGADRVIVVRHDLLKYFNQEIVAKLLAYIIKIYLPEIVLAPATTAGRTYLPAVAAMVHTGLTADCTGLDIDEENGLLLQTRPAIGGNVMATIKTPDHVPQMSTVRPKTFRIPAQEERCGEVVYPDIPAEIFKSRIEVLSAEYSGGEEADIQDKEVVISGGRGLKRPENFALIRALAELLDGGVGASRPTVEAKWISYPHQVGLSGKVVAPKFYLAAGISGAVQHLAGMQTAQKIVAVNKDPDAPIFRVADIALCGDLTDILPRLAGRIREEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEH2</accession>
    <name>A0A010YEH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidase, hydantoinase/carbamoylase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441983.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.788"/>
    <dbReference type="HOGENOM" id="CLU_024588_6_0_0"/>
    <dbReference type="OrthoDB" id="829830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="405" mass="43557" checksum="E2FE46B4AE6131A1" modified="2014-06-11" version="1">MQINIERLMRTFNQVGNIGGGENGVTRLPNSPAYKEAAVVLAGLMEEAGMTAHIDSVGNVIGCLPGKDASLKHIAMGSHLDTVADAGLYDGNLGIHAALECVNAMRDAGYRPNRSIEVIGFNFEEGSELGGTFGSRAMMGCGDALLPEVKRYFDKFGLDERKVSDAKIDAGRLFAFFELHPEQGSRLEKQGLPIGVVDSIIGIERYVVTVNGEYNAAGTTPMSMRKDSLFAAARLICEIERLSGELTDPFVATVGRIEAFPGLLNVIPGKTELYLEIRDIRAENMRGFMDRLNDFIAAEKDFKITVEQIIDKPPLALDAGLVSMLEDLCRERGISSVTLPSFAGHDAKVMAAYVPAVMIFVPSAGGISHNKLEYTDPADIKTGTELLLEAVLKLDAAPESGACAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEP5</accession>
    <name>A0A010YEP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710741.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.859"/>
    <dbReference type="HOGENOM" id="CLU_031786_2_0_0"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010964">
        <property type="entry name" value="M20A_pepV-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01887">
        <property type="entry name" value="dipeptidaselike"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="468" mass="50310" checksum="F79459DAFE95B489" modified="2014-06-11" version="1">MNEKLDRIVKSYLPRLVQSVCESVRIPSLYTEDASGFPYGLEIARAADHAMACARQLDFKVVDLDGKVCWAEYGSGDETVAVMGHLDVVSPGEGWDFEPFCGSVKNGAILGRGTQDDKGPLFSSLYALRAVADLGLPLSKRVRIIFGMDEESGKMRDVEAYLKSERPPLYAFTPDGAYPVVNTEKGTIKFTSTAILEKRSAEELSLAKISGGESVGSVPAKAEAVLKGKRADLERASNAIVETASRNGWKIKINLGSDQLTLTAYGKAAHATLPELGENAVGRLLILIRAAGISGRAGKFAGFLADKIGVEADGASLGIKASHGHCGALTVNMAMIEGDEHSITVTCGIYIPAETISFDEVCGTLERGFREAGGSFEPFAKTAPLFYAPDHPLIKTLQRGYRGATGKEPYLVSMCGGTYSKRMPNMVPYGATFENEDDRAHGANERLLITNLMESTRLMAYAILEMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEU3</accession>
    <name>A0A010YEU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bipA</name>
        <name evidence="4" type="ORF">Cloev_0854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710818.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.911"/>
    <dbReference type="HOGENOM" id="CLU_017016_4_0_0"/>
    <dbReference type="OrthoDB" id="143460at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="630" mass="70183" checksum="C28DCF9961FB0F5D" modified="2014-06-11" version="1">MQDSSKIRNIAIIAHIDHGKTTLIDGIFKAAHLFRDNQVMEERVMDAGNLERERGITIKAKHCTVEWEGYKINIVDTPGHADFSGEVERVLSMVDSVLLLVDANEGPMPQTRYVLMRALKLGLRPIVIVNKVDRPNAEPDSALDKTFDLFIELGATEEQCDFAVLYGSGLQGWFVDDLGKHEDNSKAGMNDLFKTIIERVPAPRAEMDKPFLMQVCTLSWSEYLGRIGCGRILQGTLKKGDRILRTHTRWTDYDQTSWEVVSTDTSTCAHLYVTKGLDRAEVSEVGAGDIVWFTGPENIDLGDTMSAPDLSNPAIAPLDIEEPTVSMLFLVNTSPFANQDGNAITLRQLKARIERETKTDPALRMEDLGRPDGIKVSGRGELHLGILIEEIRREGSEICVSRPEVITQHDSRGRTLEPMEELIIDVPEEYQGVVIQKLAQRKGELKNMENSGTGVLRLEFSIPTRGLIGYRGEFLTDTRGLGILASRFVGYGEWMGEINARSRGSLVSMDTGPATSYALDNLQERGTLFIKPGDPIYNGQVVGEASRLKDIPCNPAKRKQQNNMRSATKDMKTVLDVPRTVTIDTALEWIADDELVEVTPLSVRIRKMILDADQRKKARMQAGISDSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEV6</accession>
    <name>A0A010YEV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442092.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2492346_0_0_0"/>
    <dbReference type="OrthoDB" id="2170567at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="86" mass="9706" checksum="FA36989F4B29D117" modified="2014-06-11" version="1">MRPAGAESFFYDVIHSERIRGMCLDIASLPESERGPAIRALGYDFSPKELDSAVCRAYYKMRPEARAILGPGDLRDIVMKKWGKPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEZ8</accession>
    <name>A0A010YEZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442130.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.952"/>
    <dbReference type="HOGENOM" id="CLU_026974_0_1_0"/>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017663">
        <property type="entry name" value="ABC_PhnS2_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03261">
        <property type="entry name" value="phnS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458821" evidence="3">
        <location>
            <begin position="33"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="350" mass="37847" checksum="7208F8455BD40899" modified="2014-06-11" version="1">MMNLSDQIGKAWKFALLLIAVTAVFTAVAAHAAGKELVVYTALENEQINKYLATFKEENPDIDVKIVRDSTGIITAKLLAEGARTPADVVWGTAASSLLVLEKKGLIEPYAPKGLARVEKMLKDTANPPAWVGIDAWECAIVVNTAEAKAQGLPAIKSYKDLLRPEFKGKIVMSNPNSSGTGFLAVSGILQLMGEKAGFDYLDKLHENIALYTHSGSAPAKKAASGEFPVGISYGYAGVNQKKKGAPVEIVFPVEGSGWDVEANALIKKKNIKPEAKKFLDWAISDKAINALKDDYAITAVKVSGAIPEGYSKSPLSQLVKKNDLRWAAQNRDRLLKEWASRYEGKTEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF36</accession>
    <name>A0A010YF36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trp operon repressor family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710950.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1025"/>
    <dbReference type="HOGENOM" id="CLU_147939_1_0_0"/>
    <dbReference type="OrthoDB" id="1926997at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000831">
        <property type="entry name" value="Trp_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038116">
        <property type="entry name" value="TrpR-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013368">
        <property type="entry name" value="YecD_YerC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40080">
        <property type="entry name" value="PTHR40080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01371">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012508">
        <property type="entry name" value="YerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02531">
        <property type="entry name" value="yecD_yerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="102" mass="11492" checksum="9BE2CCF074981455" modified="2014-06-11" version="1">MSNQWKDEFTDQLCDSIVAITDRDEAYRFLEDVATFSEIKAFSQRLQVASLLIKGFSYPQIVQATGASTATISRVKKFVEYGADGYRDVLRKLEAAKTNEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF57</accession>
    <name>A0A010YF57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">Cloev_0980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710985.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1050"/>
    <dbReference type="HOGENOM" id="CLU_041575_5_2_0"/>
    <dbReference type="OrthoDB" id="1572673at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="207" mass="22541" checksum="8594F4C5F15816E1" modified="2014-06-11" version="1">MPVVKEVNFKGEVIGEVTLSDAVFGAPVHVPAMHQVVVAHLANCRVGTHNTKDRGDVRGGGKKPWRQKHTGRARAGSSRSPLWVGGGVAHGPHPRDYHQKVNKKVRRLAIRSALTLKVQAENMLVIDSFGLETPKTKSMIEFFAAVQSGKKPLLVLHETNMAVVKSAANIPGAYVQHVDSVNVYDLLNHDQLIATPEAVKKLEEVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF75</accession>
    <name>A0A010YF75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">Cloev_1005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711022.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1074"/>
    <dbReference type="HOGENOM" id="CLU_103849_1_2_0"/>
    <dbReference type="OrthoDB" id="1772647at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="125" mass="14145" checksum="622D5BBDF61E61FC" modified="2014-06-11" version="1">MARLAGVDLPREKRIEIALTYIFGIGPAVANDIIKVTGIDPNTRVKNLSEEEEQKLRAEIENNRLVEGDLRRDIAMNIKRLMDIGCYRGLRHRQGLPVRGQRTKTNARTRKGPKRTVAGKKKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS27</accession>
    <name>A0A010YS27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441199.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116722_3_1_0"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="43"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="115" mass="12473" checksum="C9C2B56EBA82FE36" modified="2014-06-11" version="1">MILKNQEEGIKREKLGGSGKGHALAFPITIPDQDGAFIMTTRLELEPGASVGYHLHADNEEVYFVMGGEGLYTEENESRQVKAGDIMLCRMGRSHGIENTGKETLVLGAAIAKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS46</accession>
    <name>A0A010YS46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.33"/>
    <dbReference type="HOGENOM" id="CLU_053106_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050485">
        <property type="term" value="F:oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010187">
        <property type="entry name" value="Various_sel_PB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07355">
        <property type="entry name" value="GRDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01918">
        <property type="entry name" value="various_sel_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0711">Selenium</keyword>
    <keyword evidence="1" id="KW-0712">Selenocysteine</keyword>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="1">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="425" mass="45580" checksum="5E7050DB5BFDA7BD" modified="2014-06-11" version="1">MVYKILHYINQFFAGVGGEDKADFEPKAVSGAMGPGVQLEKLFGGKADISMTYVCGDNYFAEHTDEVLADFAEVLAREEPDLIIAGPSFYAGRYGFACGHVIKKAQELLGIPGIAGMNNESPAVEMFRDDMYIIKTGNSVRAMKPALEDMAALVGKLLAKEPLGSAVFENYFHRHVRKNFFRAENGGKRAVDMLLKKMSGEPFVSEYLQEIPEKVAIAPPVKDLAKATVALLNTGGIVPAGNPDKIESSSATKYGAYSAAGCERLEAGKIISIHGGYDTSFANADPNRIVPVDVMRGLEKEGVIGKMHETFYTTVGTGASLLNGEAFGRGIAGALKEAGVDAAIMVSTUGSCTRCGAAITKEVERSGIPCAHITAIDPIAHTFGSNRVVHGVSIPHPLAKPNEDRETEYNERKNIILNALERVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS78</accession>
    <name>A0A010YS78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ig-like domain-containing surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0072</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441251.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.86"/>
    <dbReference type="HOGENOM" id="CLU_229282_0_0_0"/>
    <dbReference type="OrthoDB" id="1177619at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="961"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="1849"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="2324"/>
            <end position="2402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1943"/>
            <end position="1966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG77973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="2653" mass="271209" checksum="CE2D1BA43F53CCED" modified="2014-06-11" version="1">MRFIRQIIQQLGLSPREGGGGAKRFCLPLLALICAAALGSWLLMRPSSAAITPDTAWYESNPHAREFYISTSADLAGLAQLFNDSYNPNLYGKTFHLSADIDLGGVPWTPIGNETYVFQGTFDGGGHAVTGLYIDGSEDYRGLFGYIFNATVKDLSVSGSVTTTGGNVGAVAGCANQSTITNCVSDAAVSGGSNVGGIAGSVECSIYDPVDISGCVNGGRVSGRENNIGGIAGALNNAIARDCANAGAVTGGGSGNSGIGGIVGYGSGGGVVNCLNRGDVRAENAGANAGGIVGYYSNISAEFCTNMGRVYGGGYAGGILGNHFAGDSTVTSCASVGGVSGGGSRGAIVGGAFFTGSDGSQSRYATLSNCLWYESGSVNAGLKAAGDDDDEGKFTAAMAASADNYGGFIATYAPDPFASAIPAGKTKRLFRSWPGVKAGAVTAVSYDVSPDIGLTLSADVNKSVAATMTTSGDYRVSATATFTPLQLASGDVTPYTTENMTLRVGEGWPYLPVVYVTPNGTGEKDGSSWANAMGGADFSAMLKWINRQNSGTAYEFRVAAGIYAQKETLYLSKGVKLYGGFAGTETDIDAREIAKNVTTLTAATGASISIVTGGEDATSADTVLDGFTITGGKGTVQSDGNYYGGGIFISSSNPAIANCVFSDNNAFAGGGMFLEKSNPAIINCDFSNNSGTAAGGALYMEFSAPYIKNCAVTNNVGGGIYGQDSSIIAEGCVFKDNTYASGVGGGGIGLVEWDDGDPTILSSIKDCSFIGNSAKAGGGGLFTEKPLSIINTTFSGNSTDVNGGAIWSYIELSIANCTFSDNKAPKAFGGAISARDKLAVVNSVFRNNSSKAGNPDIHTEISSATATLQHCVIKEGGAGGDGAITSSDIFTGDPKFLTASPDDNGGPVPTMAVSAGGSAYRNGLAPGAHEIGGVSVTVPAADARGVSFDVTSADIGAYAWKAEGFSVSGSLELAAGASADLAPYAEAKLVSTDVRDTNAGRAAVWTSVNTGVATVADGVASGVARGKTTLTASFGTVSGSLPVTVLAAHGDVTEERMTDTPDANGYGSGVIAVSSDARESIAIYDALGLLSADQKLPANIDPTAKPIDASSVDVTTSADIYTSADIRGAVARYLSIDAEAEGDSPYKVRLVQVNNTVASRAGEGDTLFAKFWRFLTSFFGGNADEHADDYLPLQTNFVISEDQLPGHLAYRFGWQKNSEQDYKFTSDDMTEFIREVNPFVVVRSGDAVEARSLYDIVSGDVTKYITVERAGTTDTTSNIDHFTYTIKTRVLLFNKAGAVTVGAGKEFVMPVTLSDDAKTRASGNYFLVEDGAADDRYDLCLAFAVKTPKVLHVKQNGGADGKSGDGATWGTALTSADFADRLRQINGEVVPGADAFYAADEYGYEFWVASGDYRPTADDDSGYYFALTSNVRLYGGFAGTERSVDGRAAGNVSTLSCKLAENETSSVLAGTEVKGAVVDGFTVSGGASGLYLVNAEVRISGCRVEGNTERGFYAYSSRLEIESSLIAANGRSGIDCWSGAVTLKDSTLTGNKTGTAGGAVYMQGGICALRAENCTFSGNSAESNGGAVSFVDSSGELLLANCTFSGNSAGTEGGAGGAIANPPAGFKIYNTLFAGNTATSGKDVYAPNQGELVNCRFDAGGIEADSVVTSRDCTTADALLLTASPDDNGGPVPTIAVSAGGSAFRAGVTPGTVISGGFKTPLTDARGVSFDKAHAEIGAYAYEIASADAYVKADAPEELILGTSSDIDNVFSLAAHLTGTASPDRYAAAFNITSVASDVISVDNGALYALKTGSSTVKAESTKGTQANGKPVEFSEFSGVTKTLKVAIPVASLDISERSRVIRRGASAQFSLVLPNGYTSADIESRDIAWSLTTGTDYSITADGLSATVTAGNVSFGASSTITATIAGKTSGETKTLTAAVSTPVGETPKPPVTPANRTDGAGGESGSGILDIVGTSEDFAIYDAMKGLGAAANLPGGISADAKPIGATSADVVTSEDLFSAEQIKAAVTEYWGLGAASEDRVRLVEVQNTVASRADEGGTLFAKVWRFLVSLFKDGGNEAPDASDYLPIEAHFTIGSADIAALPDEVKEGLSAGNLLSKVNLFAVVSEDGKVSARSLADAASGDLAAYITVSGGNDAGYTVQTRVMLFDMKGGVSGDAEADKAAGARWVQPLKVSSPDQRTNEKDNYFIVQDGAEDDRYDLCLAFAAKEPNYAEVSVTASGDIESNDIEYARWTVSGDAAQHEADSSADIRGDEQSVTLIVPGGYHVTLSDETQTLSRDVKMISADVTWGGEWKITALFEKIKAESVTLDKTTLALAVGGSYKLTAKAAPAEAYANYALWTWTTSDGNVAEVAADGTVTAKAAGKATITAAANDGSGAKAECAVTVRKSAADDPAGTPAGPEAVKPEVVTPNENVVPVTPGYVTDPVKQEDVMNEIGLKAEDAAVTENGSLTVAGGLADKAAGEVIANDPDTVSKDSVISLPVTVSSADEAGMIHALGFKVSGDVFGKVDGVGEIRVLKIFTDGGGKAFTVVTAAEAIADKTVALYDANNEIVTGAIDAAATYTLTAFVLDGGEYDLGGQTDGKVIDPIAIIKQAEPPVSPTPTGGSGGGCNAGAGALALVLIPMAVRRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS82</accession>
    <name>A0A010YS82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034444945.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.91"/>
    <dbReference type="HOGENOM" id="CLU_017290_1_2_0"/>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="3">
        <location>
            <begin position="98"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG77978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="450" mass="50651" checksum="3BC554DA6B59C927" modified="2014-06-11" version="1">MQLERYNGHVEEADFLNLLMVDIAGNIRSVSLPHGYVSEKVLKEGIGFDASNYGYAKVNNSDMVAIPDMSTAFFELRGDYKMLHVLCDVVSTERETFDQYPRNVIRNAQKFLRDKNIADTAKVLVELEYYVFEEAEYASGIEGAFYRVKSSEGLGDGYSDKPRVSLHGAYHRMPPDDSYMDFRNETVALMEVLGIPVKYHHHEVAVSQLEIELDFMDMARAADMVSLAKWIIRQVASEWDLAVTFMPKPLYKMPGNGMHVHQFLEKDGRSIFPGDVLFNLSQEGLSYIAGMLSHSLSGSLLAFACPSTNSYRRLVHGYEAPVSATFAKGSRAAAVRIPGYVPKDETRVEYRTGDASCNLYFFLAAMVLAGADGIIRKLDPVALGYQSQDAKEELTFPLNLNAVLDGAERDREYLAPAFPDKLLELWTKAKRAEAEYIYNAPTPQEYELYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS98</accession>
    <name>A0A010YS98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Fe3+-siderophore transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0097</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709865.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.111"/>
    <dbReference type="HOGENOM" id="CLU_013016_0_1_0"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG77998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="339" mass="34822" checksum="150D654108CC855D" modified="2014-06-11" version="1">MTGAAELSEHRRRLFVKRLRLAALLSLLLLIAALWRLGAGEWDIPAARVAALLNPFLDEASRASPEALVVRSVRLPRFLAAVGTGGLLAVAGAVLQGLLTNPLAEPYTLGIAAGAAFGGALGFFFGSFAVTPLAFAGALASLWLVSAIAARSGGGAAYIVLAGIITNAILSAGVTFLKAIADDRLSAIVLWLMGSLSGASPLAALSVWGAAFILFVPAFIYARQIDAVSLSEGQGALLGIDEKKLRALLLAVSSLATAAAVSFFGIIGFVGLVVPHLMRSLTGPATRPLLIFSFLGGGLLLALADGAAQRLGELPVGVITALIGGPFFCWILMSRRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSA6</accession>
    <name>A0A010YSA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709879.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1666357_0_0_0"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="158" mass="17774" checksum="40AB20F84A53CAC7" modified="2014-06-11" version="1">MRKNHRENKCGNFIGKRLKSLRGDMSQGDMAKRLDITQAYLCEIEKGKRTPSFDLLCSFAEKLNTSISFLVGEHKDGLLPDGCARNSLSSFEHGDDLTFELKNIISDDRNSVSIELLLVHVKDKLRRQDPPLQGHDKDAIVSLLCGCLDMLKNKDAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSC9</accession>
    <name>A0A010YSC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Prepilin signal peptidase PulO-like peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441329.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057101_0_1_0"/>
    <dbReference type="OrthoDB" id="2046608at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010627">
        <property type="entry name" value="Pept_A24A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06750">
        <property type="entry name" value="DiS_P_DiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="DiS_P_DiS" evidence="9">
        <location>
            <begin position="13"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="8">
        <location>
            <begin position="111"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="259" mass="27595" checksum="0CC8AABC03E5B4CE" modified="2014-06-11" version="1">MDGGIYIFLGFCLGAALGSFANAAAMRTAAEKKWWGRERSVCDSCGRTLSSCDLIPVVSFIVLQGRCRVCRARIPLRHFAAELSCGALAAIFVWRFGLTPALAFAALSVPFIAFHTLTDLDTGYIYDSWAIAMAACGMLLRAVHGWGGLLDGLFGALAGFGVIGTIIIASRGRMGLGDAVLMLGVGAFMGFRLTLLSLYLGFMSGGLVVIPLLLAKRVTRKTAVPLGPFLCAGMAFAMLFGEKILSYLGYTAQWPWAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSK0</accession>
    <name>A0A010YSK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type metal ion transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0213</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441388.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.232"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_3_0"/>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033232">
        <property type="term" value="F:ABC-type D-methionine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03258">
        <property type="entry name" value="ABC_MetN_methionine_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026253">
        <property type="entry name" value="ABC_MetN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041701">
        <property type="entry name" value="MetN_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018449">
        <property type="entry name" value="NIL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF5">
        <property type="entry name" value="PTHR43166:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09383">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00930">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="322" mass="35964" checksum="1DA6AE17988EF004" modified="2014-06-11" version="1">MIEINSLGKYFGDHKVLSDISLKVDKGDVFGIVGHSGAGKSTLLRCLNGLESYTEGSVRVGGKEVRDLDEKELKLLRRDMGMIFQNFNLMNRKDVFENILFPLKVWGTPKSEAESRVNELLELVGLTGKRHEKVRNLSGGQKQRVGIARALALNPEILLCDEATSALDPKTTISILELLMDINKKLNVTIVVVTHQMEVVKMICNKVIILDGGEIVASGETDKLFLAPGEELRKLITDDYAVIPSGTNIRLMFPREVANDSIITNMARDLNINFSIVGGRIEKYRETVMGFLIINVADKDVANIEKWLGENKMYWEVMKNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSM0</accession>
    <name>A0A010YSM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.254"/>
    <dbReference type="HOGENOM" id="CLU_077931_3_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016661">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="185" mass="19527" checksum="D9016A3C8B88857A" modified="2014-06-11" version="1">MKIKAMIEISIFAVLTAVGARLMVPVPFVPFTLQTLVCMLAGLLLGPKRGAASQALYMAMGLIGIPVFTSAAGPAAVLMPSFGYILGFIGCAWLSGCLRDMFFKKYGSVTRLQYFAAAMAGVAVVYLIGVAYLYVILNFWVKSGGATFFKVLSIGFFSTIAGDAAKAALAAVIARRLEAGGVFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT85</accession>
    <name>A0A010YT85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484834.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.530"/>
    <dbReference type="HOGENOM" id="CLU_564638_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="483" mass="47117" checksum="ACF973834816EC16" modified="2014-06-11" version="1">MSNIKSVEVVESANRIAEIVEVSSRQGRAATIAVGTVTTGAPGSMAQVTNSGTLGSAVFDFVIPAGESVEFRVSDGNVQWKTTNAEAWTNLVSVAGIQGYSNYAVCSTPAAVAEKSVSIPGFVLDTGKSVLVRFANANTANAPTLNVSGTGGKDITFQGVAVPTGWIRANVIYSFVYDGVGWNMDAGYQLAEEWACKTGDTVDGIAYSAKVYASYAKSAAESALSSAATAVDAKSAAELAKAGAENARDAAAGSAAAAGAAATAAGSSASVAAAAEQSALAAKESAEAAKAAAENAQSEAAGSAAGAAGSATAAESAKVAAENAKAAAASSEAEASASATAAVNAKNDAQAAKQAAESAETGAEAAKNAAEAAAGNAAQNVSDTLAGYVSDANSAKNAAANSAAAAAGSAQEAADTVASLTFSAATPAAESEAGAPGTTNQIPRADHSHPRGPKTAVFVNGESDSAILADTKVGDIIIRKVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTB3</accession>
    <name>A0A010YTB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0527</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709637.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094156_6_2_0"/>
    <dbReference type="OrthoDB" id="2075613at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="76" mass="8073" checksum="94DEA44A80D9BF63" modified="2014-06-11" version="1">MKILLGIIHILVCLALITVVLMQHRKSGGFTGAFGGGGTQADMNNGTWQRMSGLTKVTAVLMGAFMVISILQVVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTN7</accession>
    <name>A0A010YTN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative effector of murein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710430.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.710"/>
    <dbReference type="HOGENOM" id="CLU_082099_1_0_0"/>
    <dbReference type="OrthoDB" id="1416872at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PTHR30249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="230" mass="23773" checksum="209F6A8B02689340" modified="2014-06-11" version="1">MRDFISSSAYFGLALSVGAYILGSILRRRFNYAVFNPLLLAVVLIISLLSLCGIPYKSYDHGAKYLSYFLTPATVCLALPLYRQRGLLKEYAAAILCGIAAGVAASAASIFVIARCWGLSRTVYVTLLPKSITTAIGMGVSAEAGGIVTITVVSIIATGILGNIVAEPVMKIFRITDPVAKGLAIGASAHAIGTVKALEMGEVEGAMSSLAVAVAGLATVLAVPLAAGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTW0</accession>
    <name>A0A010YTW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3042018_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="54" mass="6316" checksum="0AFCCC96E050DC60" modified="2014-06-11" version="1">MSYIPRNLQVMWLLFTLFCCIPAILAYCGKTICERNQKRRIAKKLAQRGIRIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTW9</accession>
    <name>A0A010YTW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino acid ABC transporter membrane protein, PAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0746</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445256.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.797"/>
    <dbReference type="HOGENOM" id="CLU_019602_20_3_0"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458162" evidence="9">
        <location>
            <begin position="22"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="307"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="525" mass="59272" checksum="407576CB02BFAFBE" modified="2014-06-11" version="1">MKKFIALFALILTLLSPAALFAGEAAVSAGEGEKILRWGGDSEGGFPYMFPDPKDPKKLIGFEVDIVDALAAEMGRKPVYVNNAWDNLIPGLDRNLYDIAINGLEVTPEHEETVNFSIPYYKTYLQLAVRRKDDSIKSLQDLKGKVAGTLKESYAQMVLEEVGNVEIRTYIVEANTYEDLANGRLDAALFDQPIALYSAGFNPEIKFVGPPIGEIIYAIAIRKQDKELLTEINRALVALRDSGKLREIYDKWNLWTPVMATEFNDFDPPKYEPVYYNEWAEAHRPDLTMQKRLERYWDAMPLFAKGALVTMEVSIVAMVIAISLGLFLAVTRVFAPRWLALIATWYVEIVRGTPVLIQLFFIFYGLPSVGIKFSPFWAGAIGLGLNYAAYEAEIYRTGLFAIPRTQWESALALGMTRWQAMREVILPQAVRVVIPPITNDFISLLKDSSLVSIITMVDLTKVYGQVSATYYDYFGPGIIVAIIYLILGLPFVRFARFTEKRLAAAENDGKQSYRENIYRRSTRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTY1</accession>
    <name>A0A010YTY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein Cas5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484866.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.808"/>
    <dbReference type="HOGENOM" id="CLU_097416_0_0_0"/>
    <dbReference type="OrthoDB" id="1795039at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021124">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013422">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09704">
        <property type="entry name" value="Cas_Cas5d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02593">
        <property type="entry name" value="CRISPR_cas5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="259" mass="28963" checksum="A8113AD870B83776" modified="2014-06-11" version="1">MYGFSVSLAAQTASFREPSAHLYQKTYPLPPISTIAGIAGAACGLEFSRAWRYLKENNLYLGVTGSFCGTGIDLWRYNKIAVPKSKEERDSAKKLNLAKILRNDILNREFLYDTKFTLYYAAQNSDFVCRLAEAFKDPGYAISLGNSDDIAMVRSVSDIYEVGTSAATSLKNTVIEGDLSKEVGFDWDALQKTSVSQTLRAPVIGRLIVDFEFNDMERKPKAYQQFTFLFGEHVLRTPRPAHSFCGTNVSLYCIGDRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU58</accession>
    <name>A0A010YU58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyruvate formate-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0821</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442050.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.873"/>
    <dbReference type="HOGENOM" id="CLU_009096_0_1_0"/>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010098">
        <property type="entry name" value="PFL2/GDeHydtase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01774">
        <property type="entry name" value="PFL2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0556">Organic radical</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PFL" evidence="5">
        <location>
            <begin position="9"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="4">
        <location>
            <begin position="671"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2">
        <location>
            <position position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="797" mass="88963" checksum="1A9A8957495A7D9F" modified="2014-06-11" version="1">MERHPQYLDRIDRLKEKVFETYPEIDLEDAKLLTQSFLETQGEALVTRKAKAFLKQCREKSVKIWDDELIVGNAGSKIRGGILSADVCWSVLDRELETINTRKYDKFRLPPEDKKDFEEIIRPYWKGRSNYEEWLARIPEDVAALRDNGALYIDKKAVRGWGEVTAGYEWFIKNGIEGLREKILERKSQLDATVPGDYEKEVYLDALLIVCEGMETLAARYAAEADRLAALEKKAERAAELREIAETCRRVPAHPARTFREAMQSFYFYQICIFMEQNAAAYNPGRMDQYLYPYYKADLEAGRLTPEEAQELFDCLWVKFSEPCLFQDEKSAEYSSGYPMFQNLCAGGVDKMGRDAVNDLSYMIIQATMDTKLYQPSLSVRYNMAKNPNSFLRKIVELMAMGTGFPAFHNDEVGIRMLMNKGIPLREALDWNPGGCVETNLAGKLRAYSALADINLGSVMEFVLLNGKCRKTGKLAGAQTGDPLTFASFDDLLNAVKQQLRYVIKVVVKASHIIDDICLERPVPALSLSFEECVENAKDYAWGGAKYNTGNGIICIGVSDLINSVAAVKHLVYDTKSVTMKQLLDALAGDFQDAPEIHKACKEAPKYGNDDPRADGLAAELFAYIADEIESYRSKFGVMTPGILPVSGNTPFGVEVGALPSGRRAGKPLADGVSPNGGTDTNGPTAVLKSVANIPHDRFVQGTLLNMKLDPQMINSENGINQIMALLKSLCTLGVYHVQFNVVDQKKLIEAQAHPEDYRSLLVRVAGYTAFFVELGKEVQDDIIARTVQTENGVSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUP3</accession>
    <name>A0A010YUP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_1023</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711052.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1093"/>
    <dbReference type="HOGENOM" id="CLU_049944_2_0_0"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="247" mass="26645" checksum="9C28A4A4B6D8A738" modified="2014-06-11" version="1">MRRVDRRVKNIPIKTIIPNMITSGSVFCGVSSLILTAHERFIPAALLICFAVFFDVMDGRVARSLGGSSAFGEELDSLADAISFGVAPAFLIYNAYVGVESGIWGPLTASFFALCGVLRLARFNVTHVPAGPFQGLPIPAGGLALASIVIARLPITPLVAMSAMCFVGALMVSSVPYCNAKKLKKSNVSRAKLYGLMTFIALCFFILREKAFLAMAVMYIISGLVKFDGAEWIMLHAEDERSAHEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGS7</accession>
    <name>A0A010ZGS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_602318_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="454" mass="48386" checksum="A584567923CC3C5F" modified="2014-06-11" version="1">MKTLRMIPIIILIFLAAFLAVRADSLVWTPPVADPAPETNGDVVITKFDEWNPYTYAFAVEAGQATEEEIIEELDAANCYAYGSDGSGARHEFEIKWTASGTDMTKAGVFKITGEPVIADGFSVAAGTETPHPFIPVSIQEKGKPQLNVFHTARAGSYTFPWVEPPCDPEEMTVWISEDGGEWTELEHDDCISVFKTNLVLYGFLLKDGSSYRLQADYTGGRTNMFSFTFDKNIVEYNFSGGDRDGGDLDAAAPPEVEQPVGDEDDGVDDAGGDAPVVDTPVIGTESSAAASAAYTGKRIDFMRGGEGGISVSRSTFDLEIPKETLDALAVGKNDTLSVSVTRGENGEITVALAKNGQPVDDAGPLTLSIPYESGQRTEPPLLLDSGVKIAANPDAQEENMASFTVSGPGTYTLDESGGKAAPNESQSLDLANLGALAMSFLSVAAYAVHKRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGW6</accession>
    <name>A0A010ZGW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF559 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441254.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107928_1_0_0"/>
    <dbReference type="OrthoDB" id="2013215at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="12"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="131" mass="15496" checksum="BA1167C76E17C19C" modified="2014-06-11" version="1">MSLRYGKDIIPLAKRLRRNMTPEERRLWYEFLSRYPAKFQRQKTIDRYIADFYCFSAALVVEVDGGQHYTDEGEEYDRLRSECFHKLGLAVLRFSNFDVKRCFNEVCIAIDKAVTARVEGDLPEPEGFLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGZ8</accession>
    <name>A0A010ZGZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase family protein with metal-binding cysteine cluster</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.117"/>
    <dbReference type="HOGENOM" id="CLU_000809_3_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="69"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="287"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="757" mass="82810" checksum="CA2DAD24F142D0E6" modified="2014-06-11" version="1">MNNYFAKKEPSIEALVRWIADLGGKAPAIKKLPARPAAFGSFGALDERIVNALKKRGVEALYSHQSAAGECALAGVDCVIATPTASGKTLCYNLPVMHAILLDPSARALYLFPTKALAQDQLAELGELAAFADGGIHGFVYDGDTDPVKRRQARSEGHIVITNPDMLNSGILPHHTKWSDYFRNLKYIVVDELHTYRGVFGSHLANLFSRLARICEFYGSHPTFICCSATIANPDEHAQGLIGRSVKLITESGAPASEKEIIIYNPPVIDWKTGMRRSSLFETSRIASEALSSGISTIVFTRSRLNVELLLKSIRADLAKRGADPMMIMGYRGGYLPKERRRIEHDLRSGGLRGVVSTNALELGIDIGSLALAVLHGYPGSIASAWQQIGRAGRRGAISAAVMVASADPLDQFLASRPEWFYGAPTERARIDPCNPYIQVSHVKCSAFELPFHAGEKFGGQEVDAILDYLADHEVLHRVSEADEERYYWQADSYPAAGLSLRSATGENYTITDITVETKPVVIGTMDRRSAPTLIFPDAIYFHGGKSYIVESLDTEKMQCFIREIAADYYTDGDASLRINITDDFETEGNYGWGEVVVTLTPTIFKKIKLATHENAGFGQISLPEEQMHTTACWLMMPRCRQEDAELKLAMEGLEHLIRNTAPLFLMCDRADILVTSRLKDPQLRRAAIYIIDNIPGGVGLAEGTFEIKNELVKTALGVMNSCGCRGGCPGCVGANGGEFNIKAAVRELAEQILAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH49</accession>
    <name>A0A010ZH49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP transporter, 4TM/12TM fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.163"/>
    <dbReference type="HOGENOM" id="CLU_007041_3_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011853">
        <property type="entry name" value="TRAP_DctM-Dct_fused"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02123">
        <property type="entry name" value="TRAP_fused"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="601"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="2">
        <location>
            <begin position="126"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="641" mass="68211" checksum="CBD24B46BCF59BBB" modified="2014-06-11" version="1">MNKLWKLLTEEGKKRKLSGFDALTVKYVAVIMSLYQLAQATFLTIQPQMHYAIHLTFIMVLCALIYTRTFQTNQRTSTRVPIEDWIYAAILALAGIYYCTQMETYLTRMPMVDELSSLEIVIGLLTVIAVIGLTKRCMGFVLPSIGCIFLAYALWGHLIPGVLYHRKLLAIDILDQLVFTTNGIYSSPIAAAATYVFMFVMFGSFFAASGAGDFFYKFSMAVAGRYAGGAGKVAIITSGLFGMINGSPTANVVTTGSFTIPMMKKAGYDGTFSGAVTAVAATGGGIMPPIMGTAAFLMVEMAGISYKNIAIAAFVPGVLYYLALLLIVHFRAKKCGLVGLDVSELPSVWGTLKEGWIFLVPLVVLVVMLMRGYTANLSAVVGIAAVIAASWVRKETRMHLPAVIKALEDAARSAVIVSLSCAVAGCVIAGLMTTGLSGKLASLILSLGGNSTLSALILTAAICTLLGMGMPVAAAYCLTAALCIPSLYELGLQPLEAHMFVVYFATLSAITPPVAVASYAAAGISEANAATVGWQACRIGLVSFIVPFIFVFEPMLMVTPANFCLQSVWIVTSATLGVLILCAGLEGYLKKEIPMLLRGVLVIGGLLLIYPGAITDYIGLGVMALLLVQQFAGTKFGRETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHC6</accession>
    <name>A0A010ZHC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3078393_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="52" mass="5540" checksum="2A5D4B127F16B273" modified="2014-06-11" version="1">MHIIMLLAKYPALNLMSAPPSSNMGNIVVMIRAIVNPVLHAAQGSGIYFLCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHG5</accession>
    <name>A0A010ZHG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative ABC-type transport system, periplasmic component/surface lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709413.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.270"/>
    <dbReference type="HOGENOM" id="CLU_038813_2_0_0"/>
    <dbReference type="OrthoDB" id="603910at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459049" evidence="2">
        <location>
            <begin position="24"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="3">
        <location>
            <begin position="33"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="359" mass="39697" checksum="36764092355F10A5" modified="2014-06-11" version="1">MKKGILLALLLVTAFAASAFALAPIKPEDQKPVFIYVGPVADGGYNYMHDLGRQAMEKANPGVKGSIVESVPEGPDAERVMETAIRNGAKVVYANSFGYMDHVINVAKKYPDVYFNHCSGYKVAPNASTYFGRMYQPRYLSGLVAGKATKSNLIGYVAAYPIPEVIRGINAFTLGVRKVNPNAKVKVVWIYTWHDPAKEKEATKALFDAKCDTIAMHADTGGAPQAAEELGMWVIGYNYPMDKYAPTRHLVTPVWNWGKYYDYSTKAIANGTWKSQQVWWSMKDGMVDLSKFGKDVKEDTKKLVASEKKKIIDGKWDVFTGPIKGQDGKVVVPQGKKLNDGEMLSMNWFVEGVEGTIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHH3</accession>
    <name>A0A010ZHH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0255</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family. Short subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709424.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.276"/>
    <dbReference type="HOGENOM" id="CLU_038115_2_0_0"/>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13595">
        <property type="entry name" value="PBP2_HisGs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024893">
        <property type="entry name" value="ATP_PRibTrfase_HisG_short"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="13">
        <location>
            <begin position="49"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="212" mass="22442" checksum="57945A2F7A14D5B8" modified="2014-06-11" version="1">MLTFALPTGRSLDSCVDILERAGLPTAKLKDAGRNLVIEETSFRYLLSKPSDVPAMVYYGAADLALAGSDVIEEAGIELTELLDTGRGRCVMAVAGPEEMAEKFGGHVSGLMGLKVATKYTRLAEKTFAEWGVQIKLLKLNGSVELAPALGLADCIFDVVQTGGTLKANGLRVIKETMPVSLRLVAGISSVQLRWGSLFGVVEAIDSAVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHP6</accession>
    <name>A0A010ZHP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIGR00268 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441503.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.354"/>
    <dbReference type="HOGENOM" id="CLU_061181_0_2_0"/>
    <dbReference type="OrthoDB" id="846643at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01990">
        <property type="entry name" value="Alpha_ANH_like_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005232">
        <property type="entry name" value="LarE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43169:SF2">
        <property type="entry name" value="PTHR43169:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006661">
        <property type="entry name" value="PP-lp_UCP006661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00268">
        <property type="entry name" value="TIGR00268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile and sulfur donor" evidence="1">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006661-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="248" mass="28188" checksum="CE29594767D8083A" modified="2014-06-11" version="1">MELNDFFKENTRAALAFSGGTDSAYLLYMALKCGAQVRPYYVKTPFQPRFELDDALRLARELGTELTVIEYDILDDGLIAANPADRCYHCKKKLFGLLLRERAANDGFPLIIDGTNASDEAGERPGMRALCELGVRSPLRECGLTKTEIRARSRTAGLFTWDKPAYACLATRVPAGRRIDRELLQRVEAAERELFALGFTDFRVRVFHEAARIQLSPEQMAEALKRREDILARLKKYFDIVLLDMETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHQ1</accession>
    <name>A0A010ZHQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484810.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_4_0_0"/>
    <dbReference type="OrthoDB" id="2070573at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="119" mass="13860" checksum="4F50C04EB7CD7DA9" modified="2014-06-11" version="1">MTIDEVCGSFQIDPAKLRYYEEAGLLTCRRLTDGDRDYRGEELRRIGRIESLLKAGISPETLRDNPVLLDEDAKTGGERIRLLKRQRFRLLEDIHVKQQSLDCLDYIIRKAKDETPPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHQ6</accession>
    <name>A0A010ZHQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mn2+/Fe2-transporter, NRAMP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0334</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709009.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020088_6_3_0"/>
    <dbReference type="OrthoDB" id="416257at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="422" mass="45907" checksum="0281D1547F9B5A85" modified="2014-06-11" version="1">MSEKKADGILEKKRTFKDYFMSIGPAIIIAAVVIGPGSVTTLSTMGAAYGYDPLWVIVFACFASYLYQEPAIRLVCERQMSVMDAARKKYNPAVPKFLFILLYLGTLVFQASNFIGAAMSMNYFVPGLSIVAWTNIMIISALAMALMSKQDLLENFTKVLVGLMVVSFVITAFSSGPSVGDLIKDGFSFRIPGGNWFLVIALLGTTMVPDIPVSLSALLKGKFMYGRPEEVNLPTLEKKKSAVFDLLVSLTVTAMISIAILVCSGSVLHPLGIQVKSASDMARQLTPLLGRYAGILFSLGLWGAAFSSGLFRMLLMPMIFNQAWGYEEDLKAARSRIISIGAGVVPMIIVFVFGSAPIWLVLSAQAINGMMLPAICFIVWRISADKDIMGDKVNTSLRNILLAGLFVITLFLSLRTFLSIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHS4</accession>
    <name>A0A010ZHS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3116336_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="50" mass="5378" checksum="D3BDC29B572E190A" modified="2014-06-11" version="1">MAVAALGGYIKSLLESEEFMTVFPTADSRFRMLYPYASGKCRTGALAKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI78</accession>
    <name>A0A010ZI78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type proline/glycine betaine transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0533</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441780.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072510_0_0_0"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457929" evidence="2">
        <location>
            <begin position="25"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="35"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="337" mass="37362" checksum="8B3061120E817F4C" modified="2014-06-11" version="1">MTKKGRNILLAAAAVLAVAGLFTAFGQKETEKTVITASANNWDSQNLHNAIAKLVVEHAYDGYEFGTSAASSTMNWQSLLAGEVDLDIESWTFNVPSYPDDIARGDIVDLGTLVPDSKQGLYVPRYVIEGDPARGIKALASGLKSVADLVKYWQVFPDDEKAGRGRIYGSLPGWMADEILYKKYEAYGLNKHYEYVRLGDESTLFASLTSAYNQGLPWVGYCYEPTAVTGRLDLVLLDDRPYDAALYLKGECAFPDQELKIVASKKFLTKAPELAEFFKKYKTGSSLISKALAHLDETQDGIDQTAVWLLKGNDELLEQWLPAENAKKLRDYLKTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIA9</accession>
    <name>A0A010ZIA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709698.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.610"/>
    <dbReference type="HOGENOM" id="CLU_056607_3_1_0"/>
    <dbReference type="OrthoDB" id="1777515at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="149" mass="17109" checksum="163A28EFC4FA5B19" modified="2014-06-11" version="1">MRWKIKTFEELSTSELYDILVQRCDIFVVEQRCPYPDVDGADRQAWQLIGHDEEGRLAASMRILKPGATYDTLAMGRVAVARECRGHGYAREMMERAIDFATGVLGENTIKIGAQDYLTGFYESLGFRRISEVYLEDGIPHVDMIYQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIG5</accession>
    <name>A0A010ZIG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Citrate lyase acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158489_2_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006495">
        <property type="entry name" value="CitD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023439">
        <property type="entry name" value="Mal_deCO2ase/Cit_lyase_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06857">
        <property type="entry name" value="ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01608">
        <property type="entry name" value="citD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="122" mass="13186" checksum="798E92EF1B694066" modified="2014-06-11" version="1">MTLLHTAAAGTLESSDCYVTVSPDETFKLKYSGANSEIFAKRTERLVKSVLDENNIACANVTIEDRGAIEITIKARLETALERASTPEHPDPSAQGADADAECGSAVLASWWKSVTREEGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIJ3</accession>
    <name>A0A010ZIJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484857.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041517_0_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="125"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="435" mass="49392" checksum="4DA4951FEC4DAEF5" modified="2014-06-11" version="1">MTKKEVRRVEVLSIALSGGLTNKDASELLGVCVRQFIRIKKKFLQEGAQGLVHGNRGRNPVHAITDEVRGEVVSLFKERYYDFNISHFTEHLNERECISISRSSVSRILKLEGIRSKRSVNKKPKAHRPRQRKESSGMLWQTDASSHKWFGKDGDSATLHAFMDDAAGIVTGAFFIESECFVGYAEAIKMGIRDYGLPLYIYSDRHTIFKSPKELTLEDELKGVSIHLSNFGHALNDLGIKQIFANTPQAKGRIERLWNTFQDRLAAELRLNGIRNIEEANSFLPLFLDDYNARFSVEPKVENSVYLKFDKRIDLDLVFVLRCERKIGGGNTISYNSRIYIPVDGSIYMTPGSTVEVRQTVKGEIYIMRNDRAILMKQVEMPKKATHSDSKKKAGVVSPHKPASDHPWRGRSTNVATKDDTIIQRNSDIFFDHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIL3</accession>
    <name>A0A010ZIL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase involved in chromosome partitioning</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484859.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084710_0_0_0"/>
    <dbReference type="OrthoDB" id="1370117at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="245" mass="27276" checksum="42AA272AB21E1272" modified="2014-06-11" version="1">MSGSSAETANTELLRSHRWEHTVAVTGALGSGKTEFAMSLAKAFAAAGEHIHLADMDIINPYFCLRTMTKEMEDENISLVMPRKELTWGDFRCVNPDVRAKLSDKGSRLVLDIGGDAQGAFALKQFESEIEDGGYELLFVINPYRTHTRTYKEVAAMRDELEKIGGLRISAVVANPHFMNDTEPSDCARGILTVSGFAEKLGLPLLFGIAHEKLAAEARRLLEGRVPVWELKRRILLPWERQTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIN3</accession>
    <name>A0A010ZIN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441937.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.731"/>
    <dbReference type="HOGENOM" id="CLU_058050_0_1_0"/>
    <dbReference type="OrthoDB" id="1017413at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="295" mass="30415" checksum="B350FA183324288C" modified="2014-06-11" version="1">MKAAKMLSPANLAELTAALPRMTEKSKVVAGGTDLVVAIKEGRARPDLLLNVLDVKEMRAVLKKADALEIGAAVPFGEIASAEAVRRYFPALADAAAHVGSKQIRNRGTIGGNIGSVSPAGDMLPVLLLYGASLRVAHASGEITERPFASMIEKGRLLPPSGGQVIVSVLLPLPPAGSASAFVKLGSRTEVTIARLSIAMSANFDADGRIASPTVTLGALAKAPIFAREAMTAIAGNYPDEAASARLAAALAREVDEAIPGRASQPYKRHAIRGAAADVFEKIISRRAGAPGTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIR1</accession>
    <name>A0A010ZIR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710511.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_3_1_0"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="170" mass="20057" checksum="5D975EC0272BF3C9" modified="2014-06-11" version="1">MTVKKFFDNFEEYFCVWTMAIMTILVFIQVVMRYVFSNSLSWSEELARFIFLWLSWIGASYAVKERSHFRVEMFANMIKGSCRRFFEYFVLIVWFVFSFILTWLGTELVIFIYDTGQASAAMDIPMTWPYASVPVGCGLMCIRLIVEMYKIYKGEPVGSEKGQEELEEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIS5</accession>
    <name>A0A010ZIS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0717</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441965.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.766"/>
    <dbReference type="HOGENOM" id="CLU_024867_0_1_0"/>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="454" mass="48565" checksum="D90FA59D58F63CCF" modified="2014-06-11" version="1">MEQLTQLVTDINSFIWGLWCLIPLLCGTGLYFTIRLKFVQIRKFPEAFKAVFGGINLFGKRAGKDGMSSFQALTTAIAGQVGTGNLAGAATAIAMGGPGAIFWMWVAAFLGMATIFAEATLAQVFKHKEPDGRVVGGPAFYIMNGLHCKPLAVFFSVSLIIALGFIGNAVQTNSIADACNVAFGWNKLYVGIFLAALGAYVFFGGIGRIAAITEKLVPVMAAMYLIGGAIILIMNFTQLPHAFWMIFKGAFNPAAATGGLIGVSIKQAVRYGVARGLFSNEAGMGSTPHAHAVAKVKHPCEQGYAAIISVFIDTFCVLNMTAFVIFVTGAIDGHTSGIALTQKAFSIGLGQLGVPFVALCLFFFAFSTVIGWYFYGEQNIIFLCGEKGLLPYRLIVVVFLVLGSVLQLDLAWQLADFFNGIMVFPNLVALLGLASIVSKQLNEYEKDGRLKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIU2</accession>
    <name>A0A010ZIU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ORF">Cloev_0732</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441974.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.782"/>
    <dbReference type="HOGENOM" id="CLU_013734_2_2_0"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="335"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="487" mass="51923" checksum="1989F4457BBD3DBD" modified="2014-06-11" version="1">MVVKKQDEDFNAESLQAIGIILQQGDPESLSLDPLRGEMRDFCRRIVVGEKFKAESGSLLVIPLADKNVRCVVLAGTGSESESTTDAVREAAFRVTRAAASKGLSSLSLTMARPQDERRARAAAEGAVLAGYRFSKYIEKDEKDRFAAPETVVIVDGNEKGIAEGGIMAEAQCWTRDIANEPGNVINPVALAAKAAALADELGLSCEIWDEDRIQRENMGAYYAVARGSANPPRFIHLAYEPKAAAKGHIVLVGKGLTFDSGGLDIKPADFMTTMKGDKSGACAVLGALRAAAKLELPWKVSVIIAAAENMPGGAAYRPDDILRARSGKTIEINNTDAEGRLTLADALAYASELKPDMIVDIATLTGACAVALGTTTAGLFTNNDDLGEKILKAGEMSGERFWKLPMNDPNLRKQIKSPCADLVNSGGRYGGAITAAMFLEAFVGKDIPWAHLDIAAADFVKTPYSYYVKGASGFGARTLAELVREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ92</accession>
    <name>A0A010ZJ92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">YadA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0864</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442090.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.927"/>
    <dbReference type="HOGENOM" id="CLU_266085_0_0_0"/>
    <dbReference type="OrthoDB" id="1211448at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008635">
        <property type="entry name" value="Coiled_stalk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05662">
        <property type="entry name" value="YadA_stalk"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459112" evidence="11">
        <location>
            <begin position="31"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="294"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="337"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="435"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="834"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="927"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="1084"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_anchor" evidence="12">
        <location>
            <begin position="1138"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="979"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="988"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1247" mass="127037" checksum="0DA796652A79828B" modified="2014-06-11" version="1">MKKYGQAKQIAFWLLLAALALAPFAGTAAASYTAGGGEVEDGVFYAIAIGTIDSRPPEVTGEYAIAIGASTKADGACGTAVGYFASAIGLYSSAYGQFVSAKGEGSVATGCEAQATGLYSAATGFEAEASGIRSSAYGAKAQAMGTGSLAAGSDAYAGGANGTAVGFSASAGGENSSAYGMGAYAQGTDSLAAGNGAGAVDANTTAVGASAVAKFEGSTAIGYKANATIAGSVALGAGSYANRTTTATGVYVPAGASGGGITATVKGTDKGVVSIGDATDVKGHVAFTRQLTALAAGIEDTDAVNVAQLKALDSVAVKYDNDTKTAVILNSGGAAVKLSNVADAELSDASTQAVTGKQLYAANQTIATNRTNIETNKASIETNKASIATNETKIASNTTNITANAAQLKALDDVAVKYDDTKTAVTLNSGGAAVKLSNVADAVLDNTSTQAVTGKQLYAANQTIATNRTNIETNKASIATNETKIASNTTNITTNTTGIKENKTAITAVSGDVATKYTALDGRIAANTNEIAAVSGDVATKYTTLDGRIAANEASINTVSGDVAAKYTDLGGRITANTNEIAAVSGDVATKYTTLDGRITANETNIATLDTRVTSHDTRIATNETNIAANTTSIGTLDTRVTSHDTRIATNETNIASNTTNIGTLDTRVTSHDARIATNETNIAANTTSIGTLDTRVTSHDARIATNETNIAANTTSIGTLDTRVTSHDARIATNETNIASNTTSIGTLDTRVTSHDARIATNADAITTNKLSIDTVSGDVRMLDGRVKANTASINTVSADVAGLRGEITASGVKYDDDSKEVLTLNKGGAAVRLSNVADAELSDASTQAVTGKQLYETNQTINTVSGDVAAKYTVLDGRVAANETSINTVSGDVAALRGEIAASGIHYDDPSNSVVTLNKGGNAVRLTNIAAGTADSDAVNYGQLKALGGKVETFGETLAERIGGTYDPVTGEFTVTYPDGPTPANPAAQASASSAASAPSPASAQNAAQAAAQAASTPHLSETLQNMWDAIGAVQAGNVKAGDNIVVDGTKVSVSKTPEFERVKVGNIDIREEGIDMGGKPITGLAKGEIYDGSGDAVTGGQLWNAYRRIETIDERVQVVGAHAAALSAMHPVAYNPYEPTTLSAGVGYYRSEYSMAVGIFHYARENVLLNAGIAFNSDGDTMGRAGISFALGKSGRKQPSMIKDVAAMQRQMMEMQQVLTQLKEENEKNKDTIKELKDALKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJE0</accession>
    <name>A0A010ZJE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442121.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2179246_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="109" mass="12001" checksum="7ED2E69BA900B905" modified="2014-06-11" version="1">MKKYPVLRLLNGGNAPGDGAAHDYGSVRELLAAEHSPAIIIIDSSRYLPGEGRAYYEDILNLRQSPVFCYAPIFSHVRYAVLTFWLTAFLTISAPSRGKAVPYSLAERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJF0</accession>
    <name>A0A010ZJF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-aminoethylphosphonate--pyruvate transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0893</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442136.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.956"/>
    <dbReference type="HOGENOM" id="CLU_027686_3_1_0"/>
    <dbReference type="OrthoDB" id="996960at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047304">
        <property type="term" value="F:2-aminoethylphosphonate-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01376">
        <property type="entry name" value="PhnW_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012703">
        <property type="entry name" value="NH2EtPonate_pyrv_transaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03301">
        <property type="entry name" value="PhnW-AepZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02326">
        <property type="entry name" value="transamin_PhnW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="2 5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="63"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="376" mass="41111" checksum="717917CDC73A8105" modified="2014-06-11" version="1">MTENKYLLLTPGPLTTTAAVKAAMLRDWCTWDRDYNDLVEKLRGDLVEMALRDRAKRAGYTAVLMQGSGTFAVESVIGSVIPQGGKLAVLSNGAYGRRIAEIAGILKVPAVELRFDECERPDAETLAVMLDDDPAVTHVAVVHCETTTGILNDIESVARAAKSRGKKLIVDAMSSFGGIPLFMDVLEIDFLISSANKCIEGVPGFAFVLANRAALSECAGLARSLSLDLYGQWKTMEEHGGKWRFTSPTHVVCAFAEALRELKAEGGAAARNRRYAANRDMLVRGMEGLGFKALLPAELRSPVITSFLYPDGIGFDFAEFYESLKRDGYVIYPGKLSERDTFRIGNIGDIREKQITGLLAAVERYVKRSEARPLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJM6</accession>
    <name>A0A010ZJM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="13" type="ORF">Cloev_0999</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711016.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1068"/>
    <dbReference type="HOGENOM" id="CLU_030313_0_2_0"/>
    <dbReference type="OrthoDB" id="1567535at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG78854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="431" mass="46938" checksum="D20FE90DFFC8750E" modified="2014-06-11" version="1">MLDSFRDTFRLPDLKRRILFTLAALFVYRLGAHVPTPGVDAAALGKLFDQGTLLGFLDLFAGGALSRFSIFALGVTPYINSSIVMQLLAVVVPSIEKMQKEGEEGRKKIVQWTRYGTIVFAFIQAVGMTGWLRGLGIYSGGMLDIILVSLTLTTGAVAVMWLGEIMSDHGIGNGISLLIFAGIVVRIPEAIIRTVSLVRLGEMNVLVMLLAIIIMVAVIAGCVMLQEGQRRLPVQYAKRMVGNKMYGGQSSFIPLRVNTAGVIPIIFASSVLLFPYTIAGLFQHSIARMIQQAMSPSSPIYMILYVLMIIFFSYFYTAVVFKPEDISNNMKKNGGFILGIRPGKPTTDYIEKVMGRITLGGSIALAVIAIIPTVMTGLMNINTFYFGGTAVIIVVGVALDTVHQIEGQLLMRHYEGILKRRGGKSGGLLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJQ6</accession>
    <name>A0A010ZJQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442337.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1105"/>
    <dbReference type="HOGENOM" id="CLU_043930_0_1_0"/>
    <dbReference type="OrthoDB" id="1725392at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038728">
        <property type="entry name" value="YkvI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37814">
        <property type="entry name" value="PTHR37814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="362" mass="38646" checksum="58D153F4593EB2C2" modified="2014-06-11" version="1">MCGEKISWSNVIKFAGAFVAFLIGSGFATGQEILQYFTAYGMKGLLAGLFTLICLVYVGGDFIATGFRQRFSNTNDIYRYYCGRYIGGFYDYFAIAFLYMSYIVMVAGAGATLAQYYGLPVYAGCVGMAFVSAFTVTFGLGRIVDVIGTIGPAIVLFAIGIGFAAILKNPDGIAQGARMIEAAEVEMTKVGTNWLTSGMSYVGFSMLWLAAFLAAMGQKANSAKEAVIGTTLGAAGFVAGIVIMMLGLLANIDAVAMTDIPSLILAERIYPPIATIFSIIIMGGIYTTSVPLLWSVSARFSAEKTRKSYLLTAGLAVSGCAVSLLLPFQRIVNIIYGINGYVGILLILFMIVKTARNMRKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJV5</accession>
    <name>A0A010ZJV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groEL</name>
        <name evidence="6" type="synonym">groL</name>
        <name evidence="9" type="ORF">Cloev_1095</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711196.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1166"/>
    <dbReference type="HOGENOM" id="CLU_016503_3_0_0"/>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="548" mass="57902" checksum="3369EFFF21B6DE94" modified="2014-06-11" version="1">MAKTLLFREDARRSMERGINKVADTVGITLGPKGRNVVLEKKFGSPTITNDGVTIAKEIELEDPFENMGAQLIKEVASKTNDVAGDGTTTATVLARAMIREGIKNVAAGANGMQLRKGMEDATAVVVEELKKQASPVKGHKKTAQVAAISANDKKVGELIAEAMEKVGEEGVITVEDSKSLGTTLETVEGLQFDKGYLSPYMITNPDRMEAVLDDANILIVDGKISNVKDMLPVLEKSVQLAKPLLIIAEDVEGEALATLVVNKLRGILQVVAVKAPGFGDRRKAMLQDIATVTGATVISEEVGRKLDSADVADLGHAKKVKVTKEDTTIVEGAGDSAAIKDRAAQIKKELADSTSEYDKEKLQERLAKLVGGVAVIQVGAATETEQKELKLRIEDALNSTRAAVEEGIVPGGGVALVGCTNALDKEIAKLEGDERTGAQIVRKSLTEPLYLIAHNSGMQGDVIIEKVKTLKEGQGLDATTGEYVDMIEAGIIDPVKVTRSALQNASSIAAMILTTDAVVADKPEKKESLGDMAGGMGGMGGMGGMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL19</accession>
    <name>A0A010ZL19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708588.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_2_2_0"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="175"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="380" mass="41288" checksum="904E54AACD31071B" modified="2014-06-11" version="1">MEYSAKTLTILQNLIRIRSCLPEGDELDVVKYIVSLFEPYGTAANIVRHGDNRASLVLSLKGDGNGAKRALMAHLDTVSPLEPRRWRHAPFAADFDGEKVYGCGASSSKGGVAAICAAALSLLEKKCPPFEDTLLCFTAGGDDDGMGARSLLEGGFLDGISEVIFADPTGLGIATAQKGAVWMKARVSGRRVHVLEAEKGIDALYWLLEFVRRIKGLLKEARPHFLLGGSTVYLTGVSTSEKEVCILPESACGNIDIRLIPSVDLAGFIKDTDRLIAEMTEEVPGLSIDYDILNARPPVGVSADSPIVRRIESICRREGIENARSGLGYFSDSSVIVKELGVPFVILGPGERVFDDRMDEYVYMSKVCAAQKIYEKYMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLB5</accession>
    <name>A0A010ZLB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig-like domain-containing surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441347.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388792_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459143" evidence="1">
        <location>
            <begin position="20"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="603"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="715" mass="71739" checksum="1A425A914D8B6452" modified="2014-06-11" version="1">MRSLLLTAALLLCCLSCSAAWSGGVDTEWYGDGSARSYVISAPEELAGLAALVNAASDDFTDKSITLSGDIDLNGRQWTPIGNFGTTPAKTFEGALDGGGNTIKNLTISGTGISAALFGYIGVSGVVKNITVTGSIAGDYEYLAGVADINRGVIERCENRAAVTGTLIMESVGENSYCAGIAARNYGRISSCLNNARVEGGAAAGISCENGSNRYATDLYQAEKAVIEGCENSGEIIGKAGGRATAGGIAVTANSYTLKNCKNSGPVKGRGNSALGGIVAETDSRTGAKSSSIDGCVNSGSVTLEGDGSGSGVGGIVGGTGGITKILNCRNTGNISGPDAPVGGITGRLGGDDGTVISNCVNSGTITSSYIDGESYAGGIAAINFLLIEDCVNLGDIRLPGSGVSQNWTAAGGVAGANRGSGGMIRRCASAGRVESFSTYRGGIAGYNKAHDPQDDEGIITECAWLDSSAPRAAGDAETTAGACPFTSEQQQKIVTACLLVPFSATVAQNGAADFTLELFPGTGAPFGSHVRELSAAVTPDNIAAAATKGAVVAVSGKSPGSAEMSVRVKFCPSDLSDPEFGPSETPHDIVLSAGINVVERIPAAGITLDKSAASLRKGETLTLAAAVTPADSTDAVIWASGSPEAASVADGKVTAHAPGTAVITARAGEFSAECMVTVIDTDTHYGGSGGCGAAPWSLLICLGAFCLQLRKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLD9</accession>
    <name>A0A010ZLD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0187</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709294.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.204"/>
    <dbReference type="HOGENOM" id="CLU_019200_0_0_0"/>
    <dbReference type="OrthoDB" id="854536at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="66"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="564" mass="64103" checksum="030F10BE845F163D" modified="2014-06-11" version="1">MLSSISKRNIFFIAIAAALVLLYIVPLGSYPLMEPDEGRYAEIPREMIESGNYITPMLNYVKYFEKPVFLYWMNAASFHIFGQNEFAARIGTALCALAGALATGMLGAFIYGRIAGFIAGVVTATSLLYFAIGTINITDMPLSFFLTLAFASFYAAHVKEEKKYYLLFYFACAMALLTKGLIGVVLPGAVIFFYIIFTKQWKLFYKPLYLPGIVLFFAVSVPWFYLVCRDNPDFFRFFFIQEHFLRYATKMHHRYEPFWFFFPMIPLGLVPWTAFFFALFSKKSVARSPEGAEEKRAGIYLALWFAVIFLFFSFSDSKLIPYIVPCLPPLAILIGADIVRMARDREWHGYVPLTLALTSGLLGAGLIIYPAFGEHASPAQAWPIAVKAGFGLIGMPAVVWYYTSRGGKRYKEAVRALILCSVLFISGLQDVYNIVAPMRTMKEVSEVIIKERKPGDVIVAYDEVLQGIPFYTGQRVMLVGNPGELEYGSKQPLEYGSKRPEGEGWFLSKEEFMRQWHAREKRFILVVKNGGRFEELFPRGDTGTAEKIERGKYVILFYREEPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLF9</accession>
    <name>A0A010ZLF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SOS response transcriptional repressor, RecA-mediated autopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484789.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1218088_0_0_0"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="227" mass="25304" checksum="43B41B04D6B71B40" modified="2014-06-11" version="1">METFGARLSRLRREKGLKRHDIAEPLGVDAETIARYEREEREPKVSDAVTIANILGVSIEYLSTGIASPQTHSVYAYGVSDRIIVPVLSSNDSYNLIPSADLIAASTEHIIMPKALIGNVQPHSQPFAIVTRDKSFEKFAIREGSYVVINPAERVANFDIALVFYKGKLTLKRPQYTRHGALYLFPGNNSDAIYVSADDAADINEFKIIGKAVAYQFEETKKIYHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLK1</accession>
    <name>A0A010ZLK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441415.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_602588_0_0_0"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="365"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="465" mass="52093" checksum="E532E13C72CC8A44" modified="2014-06-11" version="1">MRKEGLLYQLITALLVPALLALVLAWVVYDQFEKSMESNANNYVENLVDSVAARLDSKKWHVQPDGTYMRKPLDKDVTSIAAVLKETNLPGMFAVFQKDGTLIYGSPGKVNFLVDWVDSFDSPTPVKIRGKGGDYFTGMFYSIPDENIYIIGAVSWKMLFGSMVLLVTVWPFIMGTLAIITILAIYLLYEKVILPLRELDDEVSSLRLGYDLPDASAPEAVPELQQLRSTFVVLAQSAIDKEQLSRDYITDIVKVQEEERERISREIHDGPLQDVTALVQRLRLLALDVSDEQTINNLVNAEKVAMIGVKEMREFCNNLTPPWLDLGLRHSLAELCNSMSSQLRVQIDLEVENGDDYDDESLPASLCLAFYRVVQESINNSVNHGGATFVSVQLEKRDDRITMRIEDNGKGFNMPDDVKELRVQGHRGLSNMKERIRLAGGSLEITSALGIGTIISCEVPLQNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLP0</accession>
    <name>A0A010ZLP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441447.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_9_4_0"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="160" mass="17504" checksum="1BBC4B9A1BF2FA80" modified="2014-06-11" version="1">MPQKNNDFLKRAYRPLELLLISGVITVFAVVLLEVVSRYIFRQSIAWGAEVCQTILVWMTFLGAAVALVGGEHMEINVVMDRVNSPLMKKLLLLAGDLAILLFLACGTAGGVRLVQKTWGMTTTTLQIPAGILYLAFPIGCALMAAVVLRNIVRLFGREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLS0</accession>
    <name>A0A010ZLS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Twin arginine-targeting protein translocase, TatA/E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441475.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.327"/>
    <dbReference type="HOGENOM" id="CLU_086034_6_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="70" mass="7838" checksum="B95AE5AA70F28A67" modified="2014-06-11" version="1">MSLGFTEIILIALFILIVFGAKRIPELARAMGRASYEFKKAKEELNAESREFMEAAERAAEGEDKNTGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLS5</accession>
    <name>A0A010ZLS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavodoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441479.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.333"/>
    <dbReference type="HOGENOM" id="CLU_068890_4_0_0"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12682">
        <property type="entry name" value="Flavodoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459150" evidence="1">
        <location>
            <begin position="30"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="38"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="191" mass="19852" checksum="E998A2694A06E6A1" modified="2014-06-11" version="1">METKMLMIAIVCAAAAGLAALGQAVKAEAAVAAEPAKILIAYYSYSGNTKAVAEQIQKATGGEIFEIKPAKAYPASYNECVDQAKKECGEGFKPQLAGALPDVSKYDVVFVGTPNWWGTMAPPVLSFLSARNFAGKTVIPFMTHGGGGVQRCEADICKAAPKAAFGKIGVFSGNGGSSVAGWIKEVVTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM18</accession>
    <name>A0A010ZM18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig-like domain-containing surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441565.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.408"/>
    <dbReference type="HOGENOM" id="CLU_265352_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="467"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="927"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1255" mass="127829" checksum="665A250D351DDFC3" modified="2014-06-11" version="1">MRKDGKRFSLYLIAALILVSIASFMMLRSEAEDLQLTKDSAGYYLIATSADLKQFREAVNAGSKDINAKLTANIDLEGTSDNQWTPIRSFSGTFDGGGFTISGLYINEGNSENKGFIGTLAGGAEVSGLTIEGTVIGGGTLGGIVGKNNGTVKNCASNCEKVSGSEDYVGGIVGENNGTVTNCASNCGAVSGIGSFGGVVGWNNTGTVTNCASNCKTVSGSVHAGGIVGRNGSVSGTTRGTVTNCASNCVAVSGSGDSGGVVGWNNKGTVTNCASNCGAVSGGKNVGGVVGISDGTVTNCASNCGAVSGSDYVGGVVGRNMNATGTVTNCGWLYTTTTTSVPSVGVGAGNSTHVVSYDADASKTVVTACVSPLSVTVAKDRSAVVPFALAPGADASAAMYIETLSADVASAGIASADVASGKVTVTGRNYGTTAMAVSYKFKYTDFSKTPLSVSDGSVAVSANVGITVQDFAVTPKSATIAVGGTSKLTASGGSAAGGVTWDVSGDAVSLDKKDGTSIAATGVRRGTATVTATTKDGETDYCDITVNPATDPADPLPAENQTDKDGTGSGVLIISPDTYESFKVYDALIKLGEEGRLPDGITIASLDAVPAASTDLSIDCYIQGTGGKTSGDIIAGAIKDYWGITDTSPEKLRLVSAVSATAHAGSDETTLAKFWRILVDEVRKLLGYDNDKSTDSAYLPLQTNFTITSADIALLSDDIKTELNAGNLLDKVNLFAVVKSGDEYAARSLNDAADNSGASRGKYMTVSEDKDGNYRISTRIMLFNLPGTVSGDKTMGASWILPISSDKTSDDYFLVQDGAKDDTYAVAMALAVKTPNYATVHIATDTTSGDTPVSYDTAVTGKKGYSEKITSSDWSNAEMSGDVYTVTFAKVAGYSISVNDGSEAYTVSKDLAWGASWDVKATYSKIYVSGVSLDKTALVLAPGGSDKLTATVTPDDAYAKDVTWTTSDKNIAEIAADGTVTAKAAGKATITATANDGGGASAACAVTVRNNAGDDPTAPSLTPELVTHAIARPAEIELADNTASYVTDAAKQTTVATAAGFKDEDTALTATGALAAGSTVVNGAVNDVIAKDPTVSKDIVYALPIVESKADKAGMLHAISFKVSGDIFGEVTGAEIRVLKVFPDGTGELFTPISAPEEIADKTAALYDTNEAMVTGAIDKEADYILTIFVKDGESFDLDGNADGTVIDPVSIIKAAAAEPDQPDNTRSHNGGCNTGAALPLLAAMAAVLIIRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM59</accession>
    <name>A0A010ZM59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase (GGDEF) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_453355_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="278"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="602" mass="68468" checksum="D1AD0F99F66F90E2" modified="2014-06-11" version="1">MSCRHLREDLFLKIYVRRGRLLVIALVFFILFAAGVAALEFLCLTDSDGNLLLWKDRLLCYRSYALVCMTATVALMLLYVAAMEKMASGAEPRRGDKYGEKPHAGRRDAFRADKYKEALSSLYDRCYEFDLTHNRIIAGGEHFQGYGFAANDQRQTILDFCQNHVHPDDRELYLRFALPENNRDDFEHGVTGANIEYRTLTPDGASYRWKSAVNNVFTDPDDLSLRSLWFISDITDEREKNERLSMMAERDSLTGLYNKTRIREMVEKEIESLGKTDSPAAMIMVDLDNFKNVNDLMGHLFGDAVLVSVAQTLRGIFTGDSLLGRAGGDEFVVFLPGADANAAQRMAEEACLALSSLHRNYFGMLQFSASIGVALFPQQGKNFLDLYNKADIALYHSKNSGKARCQLYKESMGLSFAQMGTEAQDGSDTTDLFAKDPARHILRILYNAKDTELAVCGIIELIVRRFNFSRGYIFRNSDDGRHFSEIYEFCNDGVAATKEMFQNRSYEDERPDYRKHFNDDGIFWMEIESVDAELFETFDNQNIHTLVQTAVMDNGDFIGFLGFDCCDPSRVFSKEEKTVIEITGQVIASFIVRNFLYGGRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMB6</accession>
    <name>A0A010ZMB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.543"/>
    <dbReference type="HOGENOM" id="CLU_014813_3_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="535" mass="57656" checksum="48CDFA730C462FD4" modified="2014-06-11" version="1">MKMDALRYKYPSRRTLVYGSRGMVATTQPLAAQAGLDMLKRGGNAVDAAVAAAACLTVVEPTSNGIGGDAFALVWTRGRLHGLNSSGYAPALANAEELRGAGGGKMPLYGWHAVTVPGAPYAWAELNAKFGRLPLGELLEPAIHYARKGFPVSPTVSLLWKRAFAGFSKNLAGEEFAPLFECFTEGGKTPSAGQLWRCEAQARTLEKIAETNAAAFYTGELAEAIDRFSRDHHGWLRAEDLASFTPEWVEPICANYRGYDVWEIPPNGQGIVALMALNILKKFELAERECARSYHLQIEAIKLAFAEAIAEVGDPRCMRRSVGELLSEGFAEHGAALVDPSAAGLPTSRRQSSGGTVYLAAADGEGNMVSMIQSNYRGFGSGLCVPGTGIALHNRGNNFSLDPSSPNFLAPGRKPYHTIIPGFITRGNEPVGPFGVMGAFMQPQGHLQMIANMVDFELNPQEALDAPRWQWLEGRKVGLEQGVENHIIKELASMGHEVHVDYDQTSYGRGQMIIRGGGALIGATEPRADGYIAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMN6</accession>
    <name>A0A010ZMN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3006080_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="56" mass="6309" checksum="7802A05ECF89DA86" modified="2014-06-11" version="1">MTKKERAQLETLKAQLVTSFQVAKALNDLKEDDAQYWDGKMSGLATAINRLRAILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMT7</accession>
    <name>A0A010ZMT7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF126 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441939.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.734"/>
    <dbReference type="HOGENOM" id="CLU_141583_1_0_0"/>
    <dbReference type="OrthoDB" id="1732083at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002840">
        <property type="entry name" value="AcnX_swivel_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01989">
        <property type="entry name" value="DUF126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF126" evidence="1">
        <location>
            <begin position="30"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="136" mass="14246" checksum="28499E3E6168AF80" modified="2014-06-11" version="1">MPDKEYGCRGIAAGAAGGELLISADDICFYMCDPKTGRIIEDGHSLNGVDVSGKILVFPGGKGSSSVQLDGLYQLMLNGKSPGGMIVEYADTILVTCAILMKIPLVDRLPGEFYENAADGVLCRLDADKGTVALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMU4</accession>
    <name>A0A010ZMU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_220083_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="30" mass="3026" checksum="424EB94E2AE34251" modified="2014-06-11" version="1">MDGVKGTVTAPAVIVKTSAGIGSLALRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN27</accession>
    <name>A0A010ZN27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetaldehyde dehydrogenase (Acetylating)</fullName>
            <ecNumber evidence="3">1.2.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484869.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.822"/>
    <dbReference type="HOGENOM" id="CLU_028794_3_1_0"/>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013357">
        <property type="entry name" value="Acetaldehyde_DH_acetylating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02518">
        <property type="entry name" value="EutH_ACDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="11"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="495" mass="52637" checksum="E695526FCB3A1028" modified="2014-06-11" version="1">MQLRDKDLLSVQEVRELVSAAKEAQAELAGKNQEYVDRLVKSIAGAGVRNAERLGLMACEETGFGIPADKKIKNVFGSRAVYEYIKDLKTVGVIDWDEKKRVRTIAVPLGVIAGIIPSTNPTSTTFYKALISLKAGNAIVFSPHPQAKRCIMESVKVIKQAISEAGGNEDLVGCISMPTMQATESLMRHTDVALILATGGAAMVRAAYSSGNPAIGVGPGNGPSFIERSADLKEAVAQIVASKTFDNGTICASEQSVICTDDYFEEVKAEMERQGCCFLDDGERAKLGKYILRANGTMNPEIVGKSAQVIAKLADITIPAGTRIIVAPEDGVGYGHPYSNEKLAPILAFYRAPDYKQVCEKCEEILCYEGAGHTFSIHSQNEEIIAHFSARIPVSRVIVNGGSTLGGIGATTGLVPALTLGCGAEGGSSTSDNVGPLNLINKRLVAYPLKTTAEVRASMPPCPDGICESGIDEAARFDNVDVNAVVAEILKRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN94</accession>
    <name>A0A010ZN94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442053.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="M20.020"/>
    <dbReference type="PATRIC" id="fig|866499.3.peg.877"/>
    <dbReference type="HOGENOM" id="CLU_023257_2_1_0"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="224"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="434" mass="46262" checksum="2C01393EFC1B3A41" modified="2014-06-11" version="1">MAIPQNIKDEMRARRRDFHKYPESGWAEFRTTAIAAEILEKIGWKVRFAKDFIDPDEVMGYNVVPQKERTRAISQGADKKTLAKIGAYTGLAATLDTGRKGPVTVFRFDIDCVETEEAHDAEHLPEREGFSSVNPGWMHACGHDGHAAVGLALAEMLMRKKDGLRGKIRLLFQPAEEGVRGGYAMAMAGVADDADYFIAMHLGLGKPTGSVSGGTGGFLCSTKFDADFRGVGAHAGGEPERGKNALLAAAAAAVNMHAISPHSGGATRVNVGVLNAGEGRNVVPPNAHMKIETRGESAELAAYVYAKAKEVIYGAAQMYDVDVSISKQGETITAESDRKLAALIMSAAEGAEGVTLREEYRSMAGSDDACWLMRRVQEHGGLAAYVGIGASTAAGHHNNRFDFDEEAMPIALEVLLNSATLLNGTGGTPAVLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNH2</accession>
    <name>A0A010ZNH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_380749_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="712" mass="79069" checksum="2B1DFE327FE8BD27" modified="2014-06-11" version="1">MFAFIVTLSIFFLDPSVVWGFPALDELEGKAGDGPEVLAAISAMRRDALTEELELQREGVRYFFNASYGYNDEPQYVGSSTNISYEKITVGTGLSFPLFGTWNRLRINRLNAEITAIDSKYRPQMLALHNLTALRKAYAVLWIESQKIKLAKQFLRSREDVTRYLDERRDAFLLLEADNLEFRAAYDMAKRDIAVSNLRRVQALQVIRLATGVMWPMPEEPPFPTLPVFEGANADVAANPASLMRREGLEKYAELVDVTKRVDRDSALVLGITGSKEEPGDYGSGVYLGFNISEPLKTAVSREDKANLAARADYERAEREEHFARMKLEGEAEEALSYAAYAAANIEAQLSRLRAISENVREKLLRHASIAGDTFEQLQSGRYQYYRVAMDVLDSYLLFMESGADILCYAYPRGRESEPSDRTSVASAEAIGKMLSPQWFSGAFAVPAAATGLNGGVSGRPESVYIWEAAPFLRPDSRRLMLNRLRERGITKVLISFTGKELSSFQGGEARNNLKTLLAEGEAMGVSFELLLGEPTWLFPGNRGKLISIIRSMSAFPFGGIHLDIEPDSLPGAANMRPKLLSLLIDTIKESCAAARAPVSVSIHPRYLEGKLGEIVAKRLPPACIGYIAPMIYSTNADKTASRMSRILTGHPQFNFVLAQSVERSLPDNESYASAGTGVFLTSMGELGKKLSLYGNYRGIVVQDWKDYEVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNI3</accession>
    <name>A0A010ZNI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0896</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442142.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.959"/>
    <dbReference type="HOGENOM" id="CLU_039478_0_2_0"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="282" mass="30203" checksum="574188B7ACB0C8FC" modified="2014-06-11" version="1">METNIQGFIGCSSPYAEARAVLFGAPFDSTTSFRPGTRFGPAAMRSESFGIETYSPYQDRDLEDLGVFDAGDLDLPFGNAAAAIEAIEAAAAEILADGKTPVLLGGEHLVTLGAVRAAAKKYPGLRLIHFDAHADLRSDYMGESLSHASVIRRCHDILGDGRIFQFGIRSGSREEMRWSAGRTTMEKFRAETVGAAVKEIGEAPVYITLDLDVTDPAEFPGTGTPEAGGLRFAELLKALLALRGLNVKAFDLCELSPHYDNSGASTALACKTLREMLLAYCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNJ1</accession>
    <name>A0A010ZNJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484888.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_3_1_0"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="165" mass="17526" checksum="6DE0D0FD3ED0E185" modified="2014-06-11" version="1">MTTIRINEKVYSAEVNSCMSLLDFIRNVAHLTGTKKGCDNGDCGSCTVLLDGKAVLSCMMLAHQAEGHSVTTIEGLAEADDLHPVQKAFVEAGAIQCGYCTPGMVMAAVGFLSENSDPTSEEIRHAMVGHLCRCSGYENIVKAVGFAAKHLADIAVRTKFDQGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNP1</accession>
    <name>A0A010ZNP1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ORF">Cloev_0982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710987.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1052"/>
    <dbReference type="HOGENOM" id="CLU_036235_2_1_0"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="274" mass="30326" checksum="DC34FC541F64C51D" modified="2014-06-11" version="1">MGIKKYRPTTPSRRHMATPDFSEITKAKPERSLVVSLSQSAGRNNNGRVTMRHRGGRGRIKYRIIDFKRDKFGVPGKVTAIEYDPNRSARIALISYKDGEKRYILAPVGLGVGDTVFAGEGSDIRPGNALKLKDIPVGTVIHNVELEPGRGAVMVRSAGTSAQLMAKEGKYAFVRMPSGELRLVLLECMATVGQVGNEEHENVVFGKAGRTRWLGIRPHIRGMIQNPVDHPMGGGEGKSKSHKHPVSPWGTPAKGYRTRKRKPSDKFIVRRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNT7</accession>
    <name>A0A010ZNT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442330.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1103"/>
    <dbReference type="HOGENOM" id="CLU_104115_0_0_0"/>
    <dbReference type="OrthoDB" id="1453082at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010387">
        <property type="entry name" value="QueT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40044">
        <property type="entry name" value="PTHR40044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06177">
        <property type="entry name" value="QueT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031501">
        <property type="entry name" value="QueT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="160" mass="16896" checksum="5578D0B8D1B83151" modified="2014-06-11" version="1">MKNKRFFTPHGIALSALIAALYTGLTFVLAPISFGPVQFRVSEALTLLPFCLPEAVPGLFIGCLISNMLGGFGIIDIVLGSAATLAAAWITSKMPNVWLAALPPVVINAVVVGTYIAILSSTPVAWSIIYIGASQAAICYAVGVPLILYVKRSGVLEKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNU1</accession>
    <name>A0A010ZNU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional chorismate mutase/prephenate dehydratase</fullName>
            <ecNumber evidence="7">4.2.1.51</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Chorismate mutase-prephenate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">p-protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Cloev_1038</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1110"/>
    <dbReference type="HOGENOM" id="CLU_035008_1_1_0"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 22" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="19">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="20">
        <location>
            <begin position="109"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="21">
        <location>
            <begin position="299"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="18">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00014401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EXG78892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="385" mass="43562" checksum="56811C922F6CB396" modified="2014-06-11" version="1">MDHDELKKIRIEIDRTNRSLISLFERRMELVRSVAEYKRERGLPVYDAAREKEVIEQCSGWVRDPEYRGGCLWLMDKVMEASRRYENEKISAEEGARHRAASAGTPYRRVGYQGVPGSYSHQALRGYFSGQEVSESSFKLFGDVVAAVVGGEADCGVLPIENSSTGGILEVYDLLRKNDCRIVGEKIVKVDHNLMAVKGARMEDIRTVYSHPQGFSQCAEFFGGHREWELVPYFNTARSAKMVSEEKDMTKAAVASREAAELYGLEILAPRINFNSRNYTRFVIIAAGDRHDDEADKITVVIGLRHEPGSLCKALACFYDNGLNLTNIESRPMEGGSWEYFFHMDFSGHLKEKNVARAVAELKKNTSYLKILGNYRADRGRQPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNX8</accession>
    <name>A0A010ZNX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH:ubiquinone oxidoreductase 24 kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442411.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177584_0_0_0"/>
    <dbReference type="OrthoDB" id="1412344at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="80" mass="9042" checksum="F25EFF6FE44AB2FD" modified="2014-06-11" version="1">MAVVRICIGTSCYLKGAYNVLQLFQHEIEKRKLHDKIEISGSFCMGQCQNDVSVDVDGKIYSVSPETAHEFFEETIATRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZP29</accession>
    <name>A0A010ZP29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retron-type reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442464.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1221"/>
    <dbReference type="HOGENOM" id="CLU_013584_2_1_0"/>
    <dbReference type="OrthoDB" id="1581397at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="88"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="474" mass="54734" checksum="EFCC761C3D4CC03A" modified="2014-06-11" version="1">MRRKQKTAQAGCSCEDKLEAESTMKAPSIAHTENAGEERAQTLLECILTRANMAEAYKRVVKNGGASGIDGMTVQAMYGHLKEHYPELIQSLYDGSYRPQAVKRVEIPKADGGKRKLGIPTVIDRMIQQAISQVLTPIFEKQFSDGSYGFRKGRSAHQAIEQARIYYEQGYKVSVDIDLAKYFDTVNHNLLIKMLREEIKDERVIRLIRKYLKSGVMENGLISSTTEGTPQGGNLSPLLSNIYLTKFDKLLESRGHKFVRYADDCNIYVKSARAAQRVMGNCVNYLEGTLKLKVNQKKSCIGSPTKLKFLGFSLYPSKGETKIRVHEQSLKRFKDKIRKLTARNQGRSIETIMLNLRKYTTGWLGYYAIAEMKSAMLQLTGWIRRRIRQIYWKQWKRIWPKYKNLRQLGIHHRDAWRWANSRLGCWHIARTWILTTSLTNKYLASQGYDDILLRYEAMRARYRTAVYRTVRTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7S1</accession>
    <name>A0A011A7S1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipoprotein, YaeC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NlpA lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709339.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.230"/>
    <dbReference type="HOGENOM" id="CLU_067080_0_0_0"/>
    <dbReference type="OrthoDB" id="1230456at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004872">
        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30429">
        <property type="entry name" value="PTHR30429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03180">
        <property type="entry name" value="Lipoprotein_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002854">
        <property type="entry name" value="MetQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00363">
        <property type="entry name" value="TIGR00363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459345" evidence="5">
        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="259" mass="27997" checksum="5E31F79B77396886" modified="2014-06-11" version="1">MKKIALALLAALIIPTAALAAGKEIKVGVTPFPHKDIMNVVKQLVAKEGYDLKIVEFTDYVTPNTALAEKALDANFFQHVPYLENTNKEKGYDLAWVAKIHIEPLGLYSKKIKKIGELKKGAQVAIPNDATNCARALRLLEKSGLIKVKAGELVTAKDVTENPKNLKIRELDAAQLPRTLQDVDAAVINTNFAVEAGLIPAKDAIVIEGKDSPYANVLVVRGADKDTPAVKALVKAANSKEVKEYINKNLVPKGIVAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8H7</accession>
    <name>A0A011A8H7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0418</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709120.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="240" mass="26579" checksum="FE2BB5FD83DB193F" modified="2014-06-11" version="1">MNIYADDKNNKPLAEKTVEGLIGIIKGNGLKPGDRLPNEFDLAKMLNVGRSTLREAVKSLVSRNILVTQRGAGTFVSSLNGIPTDPLGLTFIERSDDEIALAFNEVRQVLEPEIAGLAALNATNKQKEEIMRQCELVEGLIKRRAPYYSEDMEFHRLLAQASGNVVMMQLVPILHHAIGKNIDRTNNELAGETVIWHKNIAVAVQRSDAVGARNAMFIHIELNRRMIYEKIVAGKNAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8J7</accession>
    <name>A0A011A8J7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441665.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_985911_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458294" evidence="1">
        <location>
            <begin position="23"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="282" mass="31259" checksum="BDD69A1BA803C43E" modified="2014-06-11" version="1">MKNIAIVIIITMLSLSVIPANASVYGSGVRPQTLYDQNGNAFQYDPNSDQYYHNGATAPVGHPLYDTPGQQGHAYYPNMGNPSPSSSYAPSVSPGTAVGVLLGAILINAIVRGSSAKAHEAPRHQQTAQIHEEPLYYNEPEASYGEQREITSQERTHYSKIWSDLRDSEEYRNNEAPTDPLAPSAEIEKLGKEMEDKCGIQATNLAIHIHQYGVKYLKTLGDSFSTQGKKIHYVNNQEVNAVFIEMSPTEALGFFYFPAQQVSRVAMIDTKHEILAYEDRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8L7</accession>
    <name>A0A011A8L7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage-related terminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441703.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_410342_0_0_0"/>
    <dbReference type="OrthoDB" id="426360at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="669" mass="76412" checksum="5E30F492F9901C45" modified="2014-06-11" version="1">MNDVSDVEAVRRMAEDETRCASSLVAFRKQYLAAPDDVDAAPFHEEWSRLLLYGREHEAIEGYRSSAKDQYVFQAYIMYCLKYPTYERSYIVIICATAEMAARKLLAITRRFQAPDCASMRVHLEKVVEDSGKAFQALYRDGMQVRVEAFGKGGAIRGLVWGAKRPDIIIINDPQDLEDMNSPATMEKDWDWFTSDVIFLGNSTRIFLIGNNLGALCIIERVFQFARQLNFDCRRYPVLDKNDRSTWPQKDPTEKMVAERESFRALGKIDSWMREKMCQVMAPESRPLKPELYGYYDPFQLDLSGSVVKIVLDPAISEKKDSDESVITACAIRDDGHKDILEMDVDRRNPYKIVDALFRMVARWNPVMVGVEAIAYQEMLAQEIERQQIKRGIYFNVVRVRGMRGRAKTSKEQKIRMRLQPQMAVGAIRLPSGAGWVPKLLQQTQEFPYGAHDDMLDTLAMLDDVREDILVPNFDQAACVCGEFPLPKNWPFWCSIVADVTGECVMLFMSCSPEGRLFITDQIFIRGTPEALYRRYLGVMGSRQPLMTVAPAVMFKDTPVSREVWADSYRGAGFRLSSAPDDYASMLTHLNQSFAVPYAGSPPHLQIFPRCKRLIWELYHAVSGEQKQPDRKSIQALMLLLSCGPKWRDMATMPLRSGRAVNYPPRDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8N1</accession>
    <name>A0A011A8N1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441735.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972196_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="286" mass="31350" checksum="E0AFA02F7049F004" modified="2014-06-11" version="1">MSGEAVFKDPKDLANGDMVVLDSGRLDIYNKIDGVRTVTPTTTLKKCESKSAPLNAWTELEGYWQEPPAVLVSPKRVPTYFSRGRYGRQRFQLGCSVAASDSPLKYRIYPSCKFTIEAGSSGTIKVGESINLWPEGSFYFPTGNSLSTIITSAQSGMGSLTVSFSWRTMYGYSNATPGTADFRANIYLDVLRAGASGSPVLETHLLVSESFFAMEQPVQTTVKTVSLGGAPCAWWLRKEGDIQNIRTGTRDIGYEHSLTLNSYSCVIPGEEFYPTDGEVFYLAIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A938</accession>
    <name>A0A011A938_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="5">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0663</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484858.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067442_3_0_0"/>
    <dbReference type="OrthoDB" id="1490892at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="240" mass="26325" checksum="4DEF996B60E55BE3" modified="2014-06-11" version="1">MSLPRLRLERCTFDNGLWHIDAEEAHHLVRVRRCYTGSLVEGLLDGEKIELKLECAGDSVFAREISRVKEDAGLPKVELLLGLLKNDQLDDALRFCAETGVYAVRLLICERSVPRYEGAKLADKMARWRKILDEATKQASAATPPLLREPVPFASADFGGLPPQRLAALLSPETKPLREIKIAPHTAVAIGPEGDWAPHESARLLAEGFIPVSLGRRIMRASTAVAAACAAAAILYEKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9B2</accession>
    <name>A0A011A9B2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycerol dehydrogenase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710624.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.794"/>
    <dbReference type="HOGENOM" id="CLU_044754_3_1_0"/>
    <dbReference type="OrthoDB" id="717704at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe-ADH" evidence="5">
        <location>
            <begin position="9"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="113"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="357" mass="38717" checksum="D40B3121FE887048" modified="2014-06-11" version="1">MERTLIPGYTIGADAYDDIVNICAQYGKKAAIIGGRQALAAARDKILRAIDGSPIESLGCFWYGGECSYENVDMLEPQVREADMLFAVGGGKAIDTCKVLAHRTGRPFFTFPTIASTCASCTSLGIVYHPDGSLRDYSFSKVPPCHIFIDTQIIADAPDRYLWAGMGDTMAKCYECTISSRGDTPSHSDAMGIALSPMCSAPILRWGEKALADCRAGRVTYELSEVILSIIVSTGLVSNFVQVDYTTGMAHAIYNGFTVLPGTEANHHLHGEVVSFGVLAMLTVDGQFDERDKILRFSRSIGLPTRLADIHASPADLPAVAEKALAGIDVRKYPYEVTRDMIISGIMELDEYSGRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9E5</accession>
    <name>A0A011A9E5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate propanoyltransferase</fullName>
            <ecNumber evidence="3 6">2.3.1.222</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + propanoyl-CoA = CoA + propanoyl phosphate</text>
            <dbReference type="Rhea" id="RHEA:28046"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58933"/>
            <dbReference type="EC" id="2.3.1.222"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Polyol metabolism; 1,2-propanediol degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PduL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.222" evidence="3 6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080676_1_0_0"/>
    <dbReference type="OrthoDB" id="1156172at2"/>
    <dbReference type="UniPathway" id="UPA00621"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051144">
        <property type="term" value="P:propanediol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008300">
        <property type="entry name" value="PTAC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39453">
        <property type="entry name" value="PTHR39453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06130">
        <property type="entry name" value="PTAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010130">
        <property type="entry name" value="PduL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="217" mass="23617" checksum="6F11C89F6AB8F19D" modified="2014-06-11" version="1">MSGAMNGITAEIVNRVLEAIAEAGLVEVEVSARHVHLSEKDWEILFGSAQKDLTPKRPLSQPGQYLSEERVSLITPKGRMDRVAVLGPFRGQTQVELSKSDCVSLGIDAPIRESGHIDGSGRITIEGPKGAVTIPQGVIIAKRHVHVPEAAARHLGFKNGEIVSVQLFTDRPVILQDVVLRVSDKFSYRMHIDFDEANAADVRGFTLGQILKQGPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9K5</accession>
    <name>A0A011A9K5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2192422_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="108" mass="12004" checksum="2E9424E5691FF716" modified="2014-06-11" version="1">MPLCLIIMAITFEGAVSMKLVTIRSRGTEAAAVMIERGFVRIDTLNEEKRSSWPETLGELVGSGQAELLNRWYLAGGRTVLENMSRRLIVTPDEAEITGEVYQTADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9V7</accession>
    <name>A0A011A9V7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tripartite ATP-independent periplasmic transporter solute receptor, DctP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442176.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_1_1_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458327" evidence="2">
        <location>
            <begin position="26"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="341" mass="37506" checksum="B54F1024B24C16EE" modified="2014-06-11" version="1">MRKCFAGIMAAVALAGVFFAGQASADIKIKTIKYAMTVPMDDVGGVGLKVFIEQIDKLSGGKIKVQTFTGAQLGSVKAHFDAAQSGGMDIVYAAASAVSGIVPEINITDLPFFLPGNYKDNWKVLDASVSKAIGKYLNERMGLHFLGFSSYGFKQFHTTNKVIHNVNDMSGMKMRILPSKLLVAEMKAWGAVPTPIDFSEVYTALQQGVADGGENTAHGTERVKWYEVQKGFTVTYHCNFLGLQVANEKWWKSLTDEEKEIVSKAAAANIKAQRDYLVADEEACIERLGKKGLKIYRLNDSERKEFIDKSRSVWDLYKAQGETSKQLFDAAQKDIKSLAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9W1</accession>
    <name>A0A011A9W1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442187.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.997"/>
    <dbReference type="HOGENOM" id="CLU_046404_0_1_0"/>
    <dbReference type="OrthoDB" id="714984at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="102"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="366" mass="41939" checksum="9DF980F4AA0869B4" modified="2014-06-11" version="1">MEIKTLKEEIQNITEPRRTSHGSIRHKLEDIIIIGLCATICGGEDYADMEELGIEREEWLRNFLELPNGIPDSETSRRVFERLNPTELSKSLSNWLDIEREKRAVIAVDGKTIRGSGNAGHMAYHVVSAFVAENQITLGEITVPEKTNEITAVPELLELIDVNGAIVTADAMSCQKKIVEKISDKRADYVIGLKENQRALHDDVVLYFKTFGKESEVIKTIDKGHGRIESREYKLFTDISWLEQRKEWKNLMSVGAVKSIVYEKEEEREFTRYFITSLTDIGEFANAVRKHWSIENQLHWCLDVIFREDASRARKDKSPLNMNVLRKQALALLNQAKYGRLSKKKMMFKAALNPEVLLDILFAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9Y8</accession>
    <name>A0A011A9Y8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0966</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442266.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_1_0_0"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="99"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="306" mass="33372" checksum="93F2418C6461A261" modified="2014-06-11" version="1">MGGELRISADNDGRRVDRVLRTLWPQVPLGAIMKAVRTGEVRLNGRKTKADARLEEGQLLYVPWEEAAGSASRNGCDVHEGDISEKRPPLETLYRDGYLWIVNKPAGLLTQPDVKGGDSLITRALAELCWTRSDYRPATVQRLDRNTTGAVIIALTGAAQRRLAELIREHKIRKLYHAVVEGIADESGRVDLPLLKDGSANMVRPDKDGQPALTLYRRISVQGARSVVEAELVTGRSHQARVHLAAIGHPLVGDAKYGSGRGAKRPLLHARTVIFPDDGELPAVLRGAAVTAPLPADMKKYEGDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA19</accession>
    <name>A0A011AA19_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="9" type="ORF">Cloev_1006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711024.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1075"/>
    <dbReference type="HOGENOM" id="CLU_072439_5_0_0"/>
    <dbReference type="OrthoDB" id="1713391at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="130" mass="14034" checksum="C32DF1C462C7C4D5" modified="2014-06-11" version="1">MAKRVQRSRKRKEKKNVSYGVAHIYSTFNNTIVTLTDKQGNALSWASGGNVGFKGTRKSTPYAAQMSAAQAAKVAQDHGVVEIDVVVKGPGPGRESAIRSLQAAGLQVNVIRDATPIPHNGCRPPKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA53</accession>
    <name>A0A011AA53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711085.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055968_2_0_0"/>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="295" mass="31026" checksum="DD6BF9702801DFCF" modified="2014-06-11" version="1">MGFKITIAGLGLMGASLAKALRGWREAEIGGVETDAEVLAKALDSGVIDKGYILNEDNARDALDADLVVIALYPRAALKFLQDFARCAKEGAVWSDLTGIKGAVAAEARRSMPAGAEFLGAHPMAGRESSGYASSDGGLFAGCNFIITPGEENTRAAVSLIKEMAAYAGAARVVETAPERHDRMIAYTSQMAHVLAAAILNSGLLFESKGFEGGSFRDLTRVGTLNPEMWSELFIMNGAPLGGVLTELEANIAALRKIIESGDGERLKAALAAATRRKAEYLNAPCSSAGKDDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA61</accession>
    <name>A0A011AA61_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Uridylate kinase</fullName>
            <shortName evidence="10">UK</shortName>
            <ecNumber evidence="10">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Uridine monophosphate kinase</fullName>
            <shortName evidence="10">UMP kinase</shortName>
            <shortName evidence="10">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pyrH</name>
        <name evidence="12" type="ORF">Cloev_1060</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="10"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711152.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1128"/>
    <dbReference type="HOGENOM" id="CLU_033861_0_0_0"/>
    <dbReference type="OrthoDB" id="1043239at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="132"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="235" mass="25487" checksum="F1C56FA95112822C" modified="2014-06-11" version="1">MERKYNRVLLKLSGEILAGDAHFGLDYEAIRGICEQIVEVAGEGIGISMVVGGGNIIRGAQTTSIERAQADYMGMLGTVINALALQDALERLGQPTRVQSAIEMRQIAETVIRRRAIRHLEKGRIVIFAAGTGSPYFSTDTTAALRASEIGADCLLKATKVDGIYDKDPAKFTGAVKMPHVSYMDALQMQLKVMDAAAFSLCQENKIPIVVFDVLKKGNLRRLLIDGENIGSMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAA0</accession>
    <name>A0A011AAA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dissimilatory sulfite reductase (Desulfoviridin), alpha/beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_1103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711212.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1177"/>
    <dbReference type="HOGENOM" id="CLU_072599_0_1_0"/>
    <dbReference type="OrthoDB" id="1128731at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="240"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="317" mass="33912" checksum="C9FDF11B90531000" modified="2014-06-11" version="1">MANGSVTPEEEKSVKALGFLRNRGTNNFSGRIITVNGKITADQMICLSEAAKLYGNGVVTMTTRLTVECQGIPFDKIEDFRAHVAKAGLSTGGTGSKVRPVVSCKGTTCQYGLIDTFELSEEIHERFYNGYRSVKLPHKFKIAVGGCPNNCVKPDLNDVGIIGQLIPNFDEESCNGCKKCAVVSACPMNAAKVADGLLQIDGAKCNNCGRCVGKCGFDAIEDGTRGYKIYIGGRWGKSTAVGRPLGKVFTDREEALAAIERAILLFCEQGKTGERFASTISRLGFEYVEKELLDGGILSRKDEILAAGLHATGGATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAB5</accession>
    <name>A0A011AAB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Met) cytidine acetate ligase</fullName>
            <ecNumber evidence="1">6.3.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tmcAL</name>
        <name evidence="2" type="ORF">Cloev_1119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetate + ATP + cytidine(34) in elongator tRNA(Met) = AMP + diphosphate + N(4)-acetylcytidine(34) in elongator tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:58144"/>
            <dbReference type="Rhea" id="RHEA-COMP:10693"/>
            <dbReference type="Rhea" id="RHEA-COMP:10694"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TmcAL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.-" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442426.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1192"/>
    <dbReference type="HOGENOM" id="CLU_038915_0_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01539">
        <property type="entry name" value="TmcAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008513">
        <property type="entry name" value="tRNA(Met)_cyd_acetate_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37825">
        <property type="entry name" value="PTHR37825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05636">
        <property type="entry name" value="HIGH_NTase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="403" mass="44242" checksum="F305080B96F5072B" modified="2014-06-11" version="1">MLYPVAGIVAEYNPLHKGHLYHAERARETCGAEAAVAVLSSNFVQRGEPALLDKWTRAKTALSCGIDLVLELPVIFSSHNAGVFANAAVDILAATGAVTHLSFGAENPDCLVDSIIDILLEEPEPFKLSLKKYLTAGFSYVEARARAAEELLPGSAALLAGSNNTLALSYMMRIKKKNYPMRPVPVKRLGSAYNCAELEEIPSATAIRAALREERRSEALLYMPAAAAGILEDALNTGRACVSHDTFWKLLRAVILRTKTEELANCAEIGEGVEYKMREAAREAKSFKEWTDACTSKRYPAGRIRRSAVHAALGLDHWTNRAAQRLGPPYIRVLGMNEKGRALLREMRERSALPVVTTYGKAARVSPYAAKAARYEALACELWEELIPNGSYGEEHKRKVIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCI4</accession>
    <name>A0A010YCI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708567.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1486620_0_0_0"/>
    <dbReference type="OrthoDB" id="1996370at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="181" mass="19453" checksum="48753C0A07819854" modified="2014-06-11" version="1">MRKNRGGITTVLVIMIVVAMLAATAWLVIGTLRKHNVEQGLASLERGDYTQAALCLEKAARYSLRPDAAVLFHLAEARLKLGDITAAKGSLEKVISLEPRNAAARYELGKIYVNEKNFGAARSEISALEEIGSEEAKGYADELKSSIQTGAVKGFFDELLKKIIPGGIPDALKNAVPGTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCQ2</accession>
    <name>A0A010YCQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transport protein ChrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441310.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018106_1_0_0"/>
    <dbReference type="OrthoDB" id="1884249at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="185" mass="19845" checksum="7C02A449D4BE106D" modified="2014-06-11" version="1">MKNLLQLYLIFLKIGSVTFGGGLAMYPILSYEFIEKRGWITEAELTDYYAVGQCTPGIIAVNVSTFVGNKRGGLPGGIVATLGFVTAPLLLLIAIAASLRSFAQVPAVRSAFAGIRVCVCVLIVNAVLRLWKNSVVDRTTLLLFAAVFAVSAGSPYMPFSVSPALIVLASLLFGIAWRRRMGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCV1</accession>
    <name>A0A010YCV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441356.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.182"/>
    <dbReference type="HOGENOM" id="CLU_035117_1_0_0"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="3">
        <location>
            <begin position="168"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="292" mass="31043" checksum="127EF1A164A92582" modified="2014-06-11" version="1">MSDKKILGFIGTGVMGASMAGHLLAAGNEVHVYNRTKERAMPLVDKGAVWEDAPADIAAKCDIIFTIVGFPKDVEEVYLGKKGLVENAKEGAVLVDMTTSSPKLARKIQAAGKKRGVGVLDAPVTGGDKGAREATLTIFAGGDSEDFEKALPYFKIMGRTVKHMGGAGDGQNAKLGNQIVIAGTMTGMCEALAFAKSCGLDLDEFIEAVGGGSAATWSLKNYGPRILKGDFAPGFFIKHYIKDMKLAEEAADEMDLDLPALTVTRELYEELAEGGYENSGTQALYCLYDPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD07</accession>
    <name>A0A010YD07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441389.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.233"/>
    <dbReference type="HOGENOM" id="CLU_000445_90_1_0"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="220" mass="24427" checksum="923D710810951552" modified="2014-06-11" version="1">MKKRIVIADDHRLVIEGIAGLLISTGEYEIVGRAGNGAEALRLIRRLKPDLAVLDITMPEMDGIDAARAVRAELPEVRILVLSVHKDLRMIMEVIKAGADGYALKEAEPDELINAVKTVLAGDIYLDSKITTLLVRDYIRKLNIPSIPEARRGDLSPRECEIVALVAGGLDAYEIAKKLCITRNTVDAHRRNIMRKLDCKNLRELTSYALYSGLVNLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDB5</accession>
    <name>A0A010YDB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GLUG motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484805.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.336"/>
    <dbReference type="HOGENOM" id="CLU_340887_0_0_0"/>
    <dbReference type="OrthoDB" id="633672at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011493">
        <property type="entry name" value="GLUG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07581">
        <property type="entry name" value="Glug"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457567" evidence="1">
        <location>
            <begin position="23"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="Glug" evidence="2">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Glug" evidence="2">
        <location>
            <begin position="673"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="832" mass="82063" checksum="690951868D5B43CE" modified="2014-06-11" version="1">MRNRKIPQFFSLLLILTLAIFAAGGCGGGSGGESGFSGGSGTAENPWRIGTAAQLNNVRNHLKAHFILAADIDMSKYENWEPIGKFAGTAEDPDMPDPSVAFTGTFNGGGHTISNLKINDTATARGVGLFGCTAGSAMISDLTIKNAAVSAKAGSGVAAVVGMALQTNDAAIKNVVLVGDNTISGISMVGGIIGGGYCGVESCTASADIVLLSGTGNSAGILAGGMSDMGTGCSIVSCDVTGGAISVGDGSGGGVSVVGGLAGCATDYSAVKNCSVKNVTITVPKGSVMIGGLVGASGKITEGAMTSDAKGFTLVENCTASGITVNAAGASRVGGIVGSGFYYSTEPYLSYYPVPASMRIVNCAVDGTITGGEAVGSIAGYIYRNSSVTACRAAVAGLQQAGAADAERVLALDDMSGMIMSVSEKITRISAGKNQNKKEDVSTNKRSGNVAFAGGSGSAGDPWLVSNAEQLDSVRNDLTAHYQLTADIDLSENKSWTPIGKFAGTAEDPDMPDPSVAFTGTFNGGRHTISNLKINDAATARGVGLFGCTAGSAVISDLTVKNAAVSAKAGNGVAAVVGMALQTNDAAIKNVALVGDNTISGISMVGGIVGGCYCGVESCTASADIVLLSGAGNSAGILAGGMSDMGTGCSIVSCDVTGGAISVSDGSGGSVSVVGGLAGCATDYKAIKNCSVDNVTITAPKGSVMIGGLVGAAGKITEGAMAADARSATLIEGCAVSGLTMKADGASRIGGIVGSGFYFSTEPYLSYYPVPAAMQIVNCSAGGTITGGEAVGSIVGYIYRNSSVTACRGAITGLQPAGAAEAAQVIALEKCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDV8</accession>
    <name>A0A010YDV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441757.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1522616_0_0_0"/>
    <dbReference type="OrthoDB" id="1850111at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021497">
        <property type="entry name" value="GTA_holin_3TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11351">
        <property type="entry name" value="GTA_holin_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="176" mass="19226" checksum="8A1BF63ACDAE4E6D" modified="2014-06-11" version="1">MNLLELIPGVGSIIEKVVPDPNKQNELKIELAKLDTQEATARLGVLQAMFQNKSIFVSGAIPALIWVFVLSVTNNYILVPWARGFGLSIPDVPLPDSIVGLVGFVITVILGKKYKDDEETYYSNGQLKNPSKKRIQAEVAACEAAKSVSTVATVDYDDPEAVDTRLKKIAREKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDZ1</accession>
    <name>A0A010YDZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mg2+/Co2+ transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441789.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.578"/>
    <dbReference type="HOGENOM" id="CLU_007127_8_1_0"/>
    <dbReference type="OrthoDB" id="822653at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="318" mass="36750" checksum="5F596E3275202A24" modified="2014-06-11" version="1">MLKITKTTESQLIELTPDRIEVGAWINLVRPSADELNAVEAITEAPQDFIRSALDPEESSRIEIEDNHILVLINVPINHDSHVYEYDTIPLGIIITPDYIVTICQEYNDVIQNFSETRFRYFSTFKRTRLLFQILYRSAMLFLKDLRQMTRRSDQIEQDLRKSMKNEELFQLLDLQKGLTYYSMSLRSNKVVVERLLRLCSNPQVSHIIKFREEDEELLDDVRVEYDQAIEMAQIQTDVLAGMMDAFASVISNNLNIVMKFLASITIVMAIPTMVASFFGMNVPVPWEGDPMGFVIVSIVALGLTIVSIWVLWKKRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE41</accession>
    <name>A0A010YE41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441847.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.638"/>
    <dbReference type="HOGENOM" id="CLU_017584_15_0_0"/>
    <dbReference type="OrthoDB" id="1462898at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027619">
        <property type="entry name" value="C_S_lyase_PatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04350">
        <property type="entry name" value="C_S_lyase_PatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="42"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="395" mass="44773" checksum="06176FF3E5A7BC1C" modified="2014-06-11" version="1">MKYDFNKYMDRRGTDCEKWDGLKDDFGRGDLLAMWVADMDFPAPPEVLEAIHKKVDEGALGYPMIPDSLRDTVRAWEKEHYGWEFGREAVSWAPGVVAGLSFAVMGLTKPGDQIIIQTPVYMPFYRTVREAGRIIAKNPLKYENGRYTMDFEGLEKLITPTCRTLILCSPHNPVARVWSREELERLADIAIRKNMIIISDEIHQDLVYSDAKHICIGSLPGMAERTVTFIAPSKTFNIAGMKASVAIIPDELLRGIYVSVLERFHLNSINILGITAMEAAYGKCGEWHRELVPHLEGNRDYMEAFVKERMPKAHMDHPEGTYIFWIDFRGYGFNDETLTDFLVNEAKVALDPGTWFGVEGDGFARLNIGTTRAMLKEGLERIAGALDIRENKKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEM7</accession>
    <name>A0A010YEM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphoglycerol transferase family protein, alkaline phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0788</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442031.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.840"/>
    <dbReference type="HOGENOM" id="CLU_021310_0_0_0"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012160">
        <property type="entry name" value="LtaS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005091">
        <property type="entry name" value="Mmb_sulf_HI1246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="261"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="634" mass="71357" checksum="E83F38D2F52A5413" modified="2014-06-11" version="1">MNHLLNSRAVYRAAGRDYRELIFFSFMILAIFLKFYFLEYEVSRAVTRVPFSVAASLAIAAALVLPASLFWHRGRLALSLLLDFMLTALVITDILHMRYYSDLFTFHNLGLSAQVGEVSESVFALFSAKDLLYFFDIPVLFGYFRIFRHISVHPFFHRITRRRFFRTCLLFAAAVAVVAFHISGYNKKVPGVLRSMWDRPAVCNNVGALTYHLADSWNTLTDRAARPKLSASELEGVREWFEGHLSRQRRPQGVFGIARGKNLIVIQVESLQSFAVGLKVGGREVTPNLNAFVREASLASNVYNQTGSGNSSDAEFLANAALYPAASGVAYTRFAGNHYAALPGVLRENGYRAVAMHGDRAGFWNRGHMYPALGFERFISKKDYVNDESIGMGLSDRSFFRQSLAMLSRERQPFYAFMITLTSHYPYSFPKLLEQAAFDAGEYKGTVVGSYLAAIHYLDREFGAFIKGLKKSGLYDKSVIALYGDHNAIPRWDSPTLSKLLGIDFTKDHNWRYVQRVPLVINVPGVKKLGWNHKMALGLVNLPRSLALLLGIDFESGLGTDIFDGSDAPVIFRNGSYVTGEIFVEPAKKSAVNVRSGEPRDYSVYAEMTERVKKTLDISDKILEYDLMPQIYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF13</accession>
    <name>A0A010YF13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442150.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_8_4_0"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="216" mass="24536" checksum="4DE2A2E72CF46500" modified="2014-06-11" version="1">MSAKTTIYFIRHGECAGNRERRIRGCVDFPLNENGIKQARALAERMKELGIGRIVTSQLSRAVMTAEILGLRLGLSPVVKDGFRNICFGSWENRLQSEIIEEFPEMWKTWLTAPESLRVDGAENIEEVRRRSLRELERTVAEYAGETIALVSHRALLKPMLAGALGIERPCFWRLHLDNAAYGILTHDQAKGFCLCGLNYTEHLKKLEIVDDFDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFB7</accession>
    <name>A0A010YFB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711177.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2842027_0_0_0"/>
    <dbReference type="OrthoDB" id="2085202at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="65" mass="7118" checksum="378A30A8AD69FBF5" modified="2014-06-11" version="1">MESTEIKASHTYKCAECGLVFETENFAERCPRCRCRVLIHKSGEMRRAKSCNCGGNCAGCGGCSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFE6</accession>
    <name>A0A010YFE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711220.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153735_1_1_0"/>
    <dbReference type="OrthoDB" id="1971787at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009366">
        <property type="entry name" value="Protein_Veg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40026">
        <property type="entry name" value="PTHR40026"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06257">
        <property type="entry name" value="VEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="81" mass="9291" checksum="F62CAE732A29B8E7" modified="2014-06-11" version="1">MAYTLESIREIVSLHKGSKISYRAANGRRKIEERTGIIKETYPSLFTVFIESQQSTISFSYTDLLTKEVELQLEPSGENLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS89</accession>
    <name>A0A010YS89_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="4">GluTR</shortName>
            <ecNumber evidence="4">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hemA</name>
        <name evidence="10" type="ORF">Cloev_0087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441272.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.101"/>
    <dbReference type="HOGENOM" id="CLU_035113_1_1_0"/>
    <dbReference type="OrthoDB" id="1358620at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="9">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="8">
        <location>
            <begin position="176"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4 6">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4 6">
        <location>
            <begin position="102"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <begin position="185"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG77988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="392" mass="43363" checksum="C4052D0EFF710E7E" modified="2014-06-11" version="1">MTMEIKIAGLDYRSASVDIREKFTFTESERRALLRGIAPHVREAVLISTCNRTELAVVSEEEPSELLHRARGCGSFFSLRGEAAVARVFEIAAGLHSQIPLEDQILGQMKEALAASREEKACGALLGQLFQRAVTAGKEVRTKFKALPHECSAAAAACAAADEFFGERGSSSGGPLRGVPALIVGSGEMGMLAARLLRDRGASVRMTQRRRRKDGAQPPSGVTLIPYESRYEAMRECRLVICATASPHFVLTAKEFADDGVRRLMIDLAVPRDIDPAFIKRPSATLVDMDGLGHEALPADFMREIKKSVTEHTRRFHEWRQIHECMPYIEDVCSFAERELAHELGCADAEEYSRVKAATRSMMNKLLFSLKERVDIDMAKECYCALAKAAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSB3</accession>
    <name>A0A010YSB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441307.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1730504_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458832" evidence="2">
        <location>
            <begin position="31"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="153" mass="15821" checksum="CCC9E42311698AD4" modified="2014-06-11" version="1">MTTMNMWRRSGKLITTSVLISVMAAAAAFASPLPPQQQQPNKGQGQQKNPPAVKPAPNNQQPGQSAPKPNQPKQNQPAPKPSNPAPNNPPAPKPTPAPKPAPKPTPAPQPQPQQPPAPPKQHHNDGSNNTGALVTGAILGAVLTTVINNSASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSV6</accession>
    <name>A0A010YSV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type cobalt transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0323</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441500.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="241" mass="26092" checksum="69D1127B091CC1EE" modified="2014-06-11" version="1">MLDIEKLSVIYPDGTRAVENVSFRLARGESAALIGANGAGKTSLVMALVGILPSTGVIMAAGTLLTKKSLTEIRSKVGVVFQNPDDQLFMASIYDDIAFGPRNMGLSEEETARRVDESLALLHIEHLRGKTALKMSGGEKRMAALATVLAMEPDIMLFDEPTAFLDPRARRNLINVLKALPHVKLIATHDLAFAEEVCERSILLKEGGIFADGPSRELLRDGRLMEDCGVEAIEGCKRSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT92</accession>
    <name>A0A010YT92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.538"/>
    <dbReference type="HOGENOM" id="CLU_688312_0_0_0"/>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="1">
        <location>
            <begin position="285"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="400" mass="42726" checksum="3048BB1C58884A73" modified="2014-06-11" version="1">MPSLFLWEVFAVDNVTAYEVLKRYQGRINAYGALCQMNWETRSGGKAWASELFLAANNAAGIKAGTGWSGPVYNKVSWEQRANGERYSQLSAFRKYSSFDEFAADYVKKIEANYPLCASRADNFYGYFAGLLAGRYGAWATDKAYFRRMVESAVTLAPEIFGAAAAAPKIKAALLYAIESDYLSDAEAAVALEVLGIGDGNDGTESVPLTPEIKTDSAISTDNTGRKIICIDPGHGGKDPGACAGGVQEKDIALKVAQMIGSSLAGYRVVYTREGDTYPTLSERAALANKIRADLYVSVHCNSATSAQANGIEVFTHTNQSKGAVAAAKAVYRRLLPVSGMNGRGVKNANLQVLRNTAMPAVLVELGFLSNAGDRAKLTAADWQEKAAVAIAAGIEEVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTF1</accession>
    <name>A0A010YTF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-nitropropane dioxygenase-like enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710296.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.616"/>
    <dbReference type="HOGENOM" id="CLU_038732_0_1_0"/>
    <dbReference type="OrthoDB" id="275153at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="13"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="373" mass="39737" checksum="31F8F937F9BE2399" modified="2014-06-11" version="1">MIDKKIELPLLTIGKHQPKYPIIQGGMGIMVSGPRLAGAVAAAGGIGTIASVGLAASSPDFDMGSGSKNIDNQNHKILSQYIKEAKETSNGGVIAVNCMCALSDYDQLVRTSCEAGADIIISGAGLPLKLPQLAEGYPDTALVPIVSSVKAAGLILNRWLKHYGRLPDAFVVETPNTAGGHLGARDQEQAMDENLSLKEVVPALVKYLKELGHNIPVISAGGIWDGKDIKDALEMGASGVQMGTRFAATEEGDASDRFKQAYIDAEEKDVVLIKSPCGLPGRAIMSPLIERYFSGALEKVGCRAGCLSHCLCRLQHETFCIADALVSAYKGDWENGLFFCGSNVSQVKSIGKVKDLIRELVEDFRLPELKTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTU6</accession>
    <name>A0A010YTU6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin</fullName>
            <ecNumber evidence="1">1.16.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-storage protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide</text>
            <dbReference type="Rhea" id="RHEA:11972"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:78619"/>
            <dbReference type="EC" id="1.16.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ferritin family. Prokaryotic subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.2" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710602.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065681_1_2_0"/>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01055">
        <property type="entry name" value="Nonheme_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041719">
        <property type="entry name" value="Ferritin_prok"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="PTHR11431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0409">Iron storage</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="163" mass="18562" checksum="46E9137DE39CFD07" modified="2014-06-11" version="1">MVIDAKMEKALNGQIRAELESAYLYLSMASWLDANDLPGCAHWMKKQAAEEQEHAMKIYGYVVSRGGRVVLEAIAAPRSEWKNATEIFQQTLEHEQKVTALIYGLVELAMEMKDYATRGLLSWFVEEQVEEEEHAMEILAKFRKLGEIPISLAMIDKELGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU38</accession>
    <name>A0A010YU38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710726.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.852"/>
    <dbReference type="HOGENOM" id="CLU_018822_6_2_0"/>
    <dbReference type="OrthoDB" id="886663at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="266"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="519" mass="56028" checksum="E676F0F9128BABD3" modified="2014-06-11" version="1">MADKTIDELCAALVAKREKAALGGGEKAIAKQHDKGKMTARERIDAVLDPGSFVEIDEFVEHRCTNFGLEKTTFLGDGVVTGYGTIDGRIVYVFSQDFTVMGGSLGEMHAKKICKVLDLALTNGAPCIGINDSGGARIQEAVDALSGYGQIFFRNVKASGVIPQFSIIAGPCAGGAVYSPALTDFIFMVDKVGIMHITGPAVIKSVTGEDVTSEQIGGARAHNATSGCAHFFAASEAECYAQARKVMSYLPSNNMEEPPFMETGDDPSRTEAELREIVPTNPNKGYDVRDVIKKVVDNGDFCEVQELYAKNIVTGFARVGGRVIGIIANQAKFMAGCLDIDASDKASRHIRICDAFNIPIVTFEDVPGYLPGLNQEMGGIIRHGAKLLYAYSEATAPKITIVMRKAYGGSYLGMCSKDLGADVVLAWPQAQIAVMGAEGAANIIFRKEIDAAEDKVAKRAEKIEEYKESFANPYRAAQRGFVDRVILPEETRPALYQALLMTESKSELRPKRKHGILPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUA5</accession>
    <name>A0A010YUA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0863</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442088.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1651300_0_0_0"/>
    <dbReference type="OrthoDB" id="2144949at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457949" evidence="3">
        <location>
            <begin position="29"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="17871" checksum="1BB6A97EA0E144CB" modified="2014-06-11" version="1">MNIKKAAASILAAAIAAASSFSPLPARAQEVAVVDVVRVVDASVPGKAGQRYIDGLKKELDAELENFKKSLGEIKEDDPRLARKQAQLSARYQSEFSRVTGLLTAELRRVTAEWLNGNKQGATVVIPAGTTLAAAPESDVNAEILRRLNTVAIDFSLKETGKGDRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUB2</accession>
    <name>A0A010YUB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Fe3+ transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_0_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458167" evidence="2">
        <location>
            <begin position="27"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="334" mass="36622" checksum="2CAD09E9B0017317" modified="2014-06-11" version="1">MYSSRKAVSLLMAVALVMVACTGAMAATLNAYTVMPEKYASKVFEQFTKDTGIKVNFIRFSSGEALARLVAEKNNPQVDILLGGPADIYTAGQKDNVFAVYVPKEQKLTPAEYRDPGNHWTGIGLIPLCFLTNTDFLKKNNLKAPGSWQDLLNPAYKNGLQMADARTSGTATERIYSLIGVYGVDGAFDYQKKLHKNVQLYTKSGAGGAMPIAQGQAASGIFYLVDALDIQQQGYPVIITYPKEGVTFGIEATGMIAGAKNPQEAKKFIDWATSPKLGQFFVDQKINYIPVVKGVKITNPALDMSKEKLLKVGAEHKGDKRKSYVERWINEVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUF5</accession>
    <name>A0A010YUF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710901.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.965"/>
    <dbReference type="HOGENOM" id="CLU_705475_0_0_0"/>
    <dbReference type="OrthoDB" id="703457at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024258">
        <property type="entry name" value="DUF3798"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12683">
        <property type="entry name" value="DUF3798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458170" evidence="1">
        <location>
            <begin position="24"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="44031" checksum="B8C675879B12FADD" modified="2014-06-11" version="1">MKKAMLLLFAALLALFVSTAAMAAEAPFHIGIVTGTVSQSEDDLRGAELMIKKYGDVAKGGMIQHLTYPDNFMSEMETTISQIAGLADDPKMKVIVVNQAIPGTAEAFRRVKEKRKDILCFAGEAHEDPNVITSVADMAINADFVSRGYLIIDTAKKLGCKTFVHISFPRHMSYETLGRRRAIMEQACKDLGIKFVFETAPDPTSDVGVAGAQQFILEKTPAWVKKYGKNTAFFCTNDAHTEPLLKQLAKYGGYFIEADLPSPLMGYPGAFGIDLTKEAGNWPVILKKVEKTVSDSGAKGRMGTWAYSYGYTNSAALAEFGKRIVDGKAKLNSKKDLLACYAEFTPGAKWNGQNYTDLGTGVTKKNMMLIYQDTYILGKGYMKATDVKVPEKYQKIKFSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUH7</accession>
    <name>A0A010YUH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442215.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166097_0_0_0"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="11079" checksum="1FFDC13F4F2D8C4B" modified="2014-06-11" version="1">MRIESLTVRNYKVFKSIAIRNIPNMAVFLGQNGVGKTTFFDIFGFLHDCLNSNVRAALAKRGGFSEVISRDQRGDIYFEIKFRPSEKDYIKNDRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUT1</accession>
    <name>A0A010YUT1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murJ</name>
        <name evidence="10" type="ORF">Cloev_1072</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MurJ/MviN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1140"/>
    <dbReference type="HOGENOM" id="CLU_006797_5_2_0"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="627" mass="67546" checksum="8DFB6015C70BDE5B" modified="2014-06-11" version="1">MPEAAKNGAVSPETAEKPAETQDPENTIGSKRPDALTGCAAPSSCEARSSENTIGSKRPDALTGCADLPLREAQGFENTTEVKRPDALTGCAAPSSCEARSSENTTGSKRPDALTGMVFHAMRMMAGTLVSRVLGLIREMLTAALFGATRQLDAFFVAYTLANLSRQLLAEGALSASFVPVFSRTLSADGRDSARKLANEALTVLIFGCSFVVAVGLIFAPVFVDIMAPGFASHERALAISLTRIMFPFLMLVSIGALAMGVLNSMGSFFVPAIAPAVSNLVYILFLLAMRSRLSIWNLAVAVLLGGAFHMLLQVYWCGRLKMTLRPALPNRRDPQLRSMMVLFLPYAAGLSLNQLNPVISRMLGSYLAAGSISVLTYADRVLQLPLGLFVIAISQAVLPMLSRQDPNKTGEFRDFIRDAMRFNLFVVLPVAAGLCIVSSEVVHILFYRGAFSVWAWHATATALSLYALGLPGMASSTVIMRAIYARRMPRAAVMITGVTVAVNLCASVILMRFFAYAGLAAASASAFTAASFFAAWMLSRNIGEKLGIFDMKWLWKVMFPLLLMGAALLAFKHILPYPAEAKLLLRVLWLAVSIAGAALIYAVATMALRCPEWRWIKDAARGRAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUW2</accession>
    <name>A0A010YUW2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pur operon repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711216.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1179"/>
    <dbReference type="HOGENOM" id="CLU_088227_0_0_0"/>
    <dbReference type="OrthoDB" id="1231912at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045982">
        <property type="term" value="P:negative regulation of purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015265">
        <property type="entry name" value="PuR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010078">
        <property type="entry name" value="PurR_Bsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43864:SF2">
        <property type="entry name" value="PTHR43864:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09182">
        <property type="entry name" value="PuR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PuR_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="126"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="268" mass="29265" checksum="B10D2825A6BD18A3" modified="2014-06-11" version="1">MRGQRTERLVRLAAKFMLCPSKLISLTDLASKFNVSKTVISDDVEVINSAMVAEGFGQMQVDRGRSGGARFVPICTPEYRQTLLSEIAEKLTDPERNLPGGLIYYSDLIFNPETALSLGYCMASLFTDAEPDVVMTSEVKGIPIAMFAAYALGVPLAVCRFRNRPSDGAAVGVHYPTASGDVKTMYIGTRQMRRGCRVLIVDDFMRGGSTASGMLLMAKQFDAEVAGIGVFIAYDEPKEKTVPNYRSLLTLKHSSEGQNRLAVTPGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGV0</accession>
    <name>A0A010ZGV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441237.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1599849_0_0_0"/>
    <dbReference type="OrthoDB" id="2118455at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="18705" checksum="0B5998BAC3FDB0E1" modified="2014-06-11" version="1">MIRCWHRRVTELPAEVAGNACEAGEFGRYFYPYWLLDLAVSVKFPFIAPRRERLLLAVDAVNSGAGFPPPGGIYETEADEDELVSPHIAKDELDGARLSQMIRFGMKKRARAWSDISYTINGIELVYKECSLWRVRYSNGSESGISLDTLTGEYGIIPINEGIKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGV5</accession>
    <name>A0A010ZGV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-polyprenylphenol hydroxylase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="2">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="1">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711993.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.71"/>
    <dbReference type="HOGENOM" id="CLU_003827_1_0_0"/>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="62"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG77964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="281" mass="30861" checksum="8444AB1B4516879D" modified="2014-06-11" version="1">MFKIVSKQKLAPKEFDIWVEAPRIADHAKAGQFVVLRVNDHGERIPLTIADYDTEKGLIRLIFQVVGKTTAAMSGLNVGDCIQDISGPLGSPSEIENYGTVLMVGGGVGIAALYPIIKALKLAGNKVITILGGRTSDLVIMKDECRKYSDELIITTDDGSEGMKGVVTEAMKMVVERGDKIDRSWCIGPSIMMKFGTKAAKELGLPIWVSLNPLMVDGTGMCGCCRVTVDGKIFFACVDGPEFDGHKVNWDEFMSRLRQYKDEEKISMEKYEAEVGEPTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGX6</accession>
    <name>A0A010ZGX6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0083</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709846.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.97"/>
    <dbReference type="HOGENOM" id="CLU_011276_6_0_0"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="8">
        <location>
            <begin position="269"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="484" mass="51318" checksum="D2E42F135ACD7E8A" modified="2014-06-11" version="1">MTLKKGHVALIGAGPGDAGLFTLRGRELLEAADCVVYDRLVGDGVLAMMPPAAEKINVGKTGGGDSVPQREIEEILVREAKKGRRVARLKGGDPFIFGRGGEEIEALNREGIPFEVVPGVTSALGGPACAGIPVTHRGVARSVHVITAHTKEGTIAPVDYDALAKLGGTLVFLMGASAVAEICAELRRAGMAEETRAAALENAGTAAQRLITGTLATLTARCAEEKLRSPALIIAGEVTALAGEFAWKKFLPLAGRKVIVTRPRERAGRLSAMLRARGAEVVELPCISTRRIEAELPDFSKYGWLGFTSVTGVEALFALLAEKGRDIRDIGAAKIAAIGPATAGALKERGLVTNYMPEVYDGLHLARGLAEITYDTPVLMIRAKEGSPELTAELAARKINFTELPLYETIYEQTGIIPRGADTAIFTSASTVRGFKAAMPELEIERACCIGEQTAAAARRAGFKRIITAQRATLESLIDTLEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH25</accession>
    <name>A0A010ZH25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709216.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116722_3_2_0"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="38"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="109" mass="12033" checksum="519B162E4796C703" modified="2014-06-11" version="1">MLIDFEKIAASVIHNFYGGEKETEARMFFDGTNRIAYSTLAPGASVGMHLHDNGSEIVYVLKGRGMALYDGGTEELSPWLCHYCPKGHSHSIVNDGSEELIFLSVVPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH73</accession>
    <name>A0A010ZH73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate 4-decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441359.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.188"/>
    <dbReference type="HOGENOM" id="CLU_038911_0_0_0"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022518">
        <property type="entry name" value="Aspartate_4-decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03801">
        <property type="entry name" value="asp_4_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="176"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="541" mass="61249" checksum="9ED6944F8D031BA4" modified="2014-06-11" version="1">MDMPTKKQEKAYETLSPFEVKNVLIEMASKHARAASSVMLNAGRGNPNWIATEPREAFFTLGRFAITESRRVWDEGILAGLPEKEGMGSRLAGWLDVNSMMPGADCLKRSFQYGVNILGFDADEWAYELCDGILGCHYPTPDRIMPCCESAVREYIIKELEQGGAQDQDFDLFATEGATAAMVYIFRSLLNNGLLKPGDTIALGTPIFTPYIEIPNLPWYSFKTVQVYADGTELVGGEPRHSWQYSDRELEKLADRQVKVFFIVNPSNPGSVEISPETAQKIKNIVTAKNPQLMIVTDDVYSSFADDYRSLFDTIPYNTICSYSFSKYFGCTGWRLGVIGIHRKNVFDDMIAAMPAAQRIKTAKLYAELAVDPEKIKFIDRMVADSRDIALNHTAGLSVPQQVQMALFAIHSLIDKTNAYNRLTKDIIRRRCKDFWNNLKWPLPLSPHSTAYYQLLDVSLWAKEKYSEGFAEWLMKNFEPIDILFRLAENPNVVLLPGEGFDAPDWSVRVSLANLPDHAYREIGRDLVTILDEYYSQYKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHN0</accession>
    <name>A0A010ZHN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-methyltransferase involved in polyketide biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441483.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069348_0_0_0"/>
    <dbReference type="OrthoDB" id="847145at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016874">
        <property type="entry name" value="TcmP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028177">
        <property type="entry name" value="Polyketide_synth_Omtfrase_TcmP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="266" mass="30933" checksum="C70627383A114400" modified="2014-06-11" version="1">MKLTGVEETTLIPLWARAYETTRKGEHLIEDPTAAELINKIDYDFSKFAEGKLSQAGVAVRSAILDREARRFFAEHPKAICINLACGLDTRFQRVDNGSIQWYNLDLPHVMQLRSELIPNTNEREHEITASLFDESWPGMVPRNGEDVLIIMEGASMYFSKEQMCQFFSLAAEHFPGAFLLMEVMTPFMIKQQKHHDTVDTKKAPFLWGVTDGKEIETLHKKLRFLRQWTFYEGFRRRWGLFGLLSLIPWWNQNCNDKIVCLEIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHU2</accession>
    <name>A0A010ZHU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isopropylmalate/homocitrate/citramalate synthase</fullName>
            <ecNumber evidence="4">2.3.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709037.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.391"/>
    <dbReference type="HOGENOM" id="CLU_578347_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="472" mass="50836" checksum="1959D4EF4D056035" modified="2014-06-11" version="1">MKRIKFTDITLREAARGLEGALSFKEIIEMAKILDRLNLDVISLAPIANVKIDSLLVRTVAAAVKKSTLSMPVGYTEAGVDTAWSAVAEAAHPRLYVEAPLSAVQMEFVCNKKPEGIIEMIGKLVRKSRGLCEDVEFAAVDATRSEPEFLYQALRTALAAGASTVTVCDSAGTMMPYEFNNFVKEIYANVPELKEAALAVKCSNELSMAAACAVSAVKAGASEVDVVVSGGCAPELETASHIIRTRGDDCGFFSGIKYTELHRSIAQMHWISRSERSKTSAFDTGFSISDGSGIRLDANDDITAVGKAVERLGYDLSEEDMVKVYDTFINVAAKKSVGTKELEAIIATSALQVPPAYELVSFVINSGNVISATANIHCRRDGEDLFGLAVGDGPIDASFLAIEQITGHHYELDDFQIQAVTEGREAMGSTLVKLRSNGKLYSGNGISTDIIGSSIRAYFNALNKISYEENHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHV1</accession>
    <name>A0A010ZHV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron only hydrogenase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441568.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.410"/>
    <dbReference type="HOGENOM" id="CLU_027268_0_0_0"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007202">
        <property type="entry name" value="4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04060">
        <property type="entry name" value="FeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="SSF53920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51656">
        <property type="entry name" value="4FE4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S" evidence="7">
        <location>
            <begin position="384"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="436"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="602" mass="67135" checksum="C30D720A039D0467" modified="2014-06-11" version="1">MKYINVAEANCKNCYKCLKVCPVKSIKYSNNHVEVLENECILCGRCIRNCPQHAKSLVNDISAIKQAVGEQGAARTADASAGLPPEVFSNVRQGEQGAARAIAALAPSYIASFGAENRFRLAGALHRLGFDAVEETSVGAHAVTKEYARILESDSMDNMITTCCPSVVFLVQKYFPQLTPQLAQVLSPMEAHGEFLRKKYGDDALIVFFAPCISKIEEARVSEKRFIDGVVTFKQLARWFIKEDIELEKCAEGYFGNDPSSSAIYPVFEGIVKDVRANLPEDSHVFNKYTFLSVQGAKDVIELLEEISEGRIHNCFIEASTCYGSCINGPEKPDTEYHPVSTGIDMIRYLRAEKNIREADISSLDLRRHIEPKPLREDIPDEETIRSILAEIGKTKPEHELNCGSCGYRTCRDKAIAVYQNKAELYMCLPYMSQISETLANVTLSVSPDYIIAVDHDLRVKECNIAAQHLLKLTKNEIVGRRIEEFLDPLDFALAVGEERNIPLHKVSYDERGITVNQTIIYIPEQGLAIAFLHDVTKQEQETESLNKLKLETMEMAQNVIDKQMTVAQEIASLLGETTAETKVTLTKLKDLIVYDGNNGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI24</accession>
    <name>A0A010ZI24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441701.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1955786_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036764">
        <property type="entry name" value="Peptidase_Prp_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118010">
        <property type="entry name" value="SSF118010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="128" mass="14492" checksum="37A20BBDF06FA4CF" modified="2014-06-11" version="1">MKRLRAVPTTVRFFRDKDRRCVRVDFRGHAIADVSTKYEEDALLDGVCACAGVSLLSSFMEILVMLGGAERYEVRSFNDGPEEVPVKSFRWEADAEAMQIPVEALYRTVQALSVEFYPFVHVQDVLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI41</accession>
    <name>A0A010ZI41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484835.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1692427_0_0_0"/>
    <dbReference type="OrthoDB" id="1770019at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="155" mass="16472" checksum="3C8A8EE604973797" modified="2014-06-11" version="1">MSDILEILARGDGGLASLLKSVLLDSEGKVPADRLRIVGALASGAIIESGSNANGRYIKYADNTMICTQVVNLGTMTVAQNDGALVSWAYPAQFVDTEDLCIIAQPTGWASNRFVANLYPNTTTYAYGGCFAITGTWNLTGATYLVQIAIGRWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI49</accession>
    <name>A0A010ZI49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441756.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2205447_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032126">
        <property type="entry name" value="LydA_holin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16083">
        <property type="entry name" value="Phage_holin_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="107" mass="11490" checksum="1B9DDF55F96FAC6E" modified="2014-06-11" version="1">MKMVDDFVTAALAMLPTIVITMIGNTVRYTRHHRQEPFSPGEFACGMFAAAFMGVMIHAFCYVIGASGWLQMAVGGMCGYAGASLLDTVAALMVKQIKVFFGGGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI92</accession>
    <name>A0A010ZI92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441801.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.589"/>
    <dbReference type="HOGENOM" id="CLU_705475_0_0_0"/>
    <dbReference type="OrthoDB" id="703457at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024258">
        <property type="entry name" value="DUF3798"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12683">
        <property type="entry name" value="DUF3798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458314" evidence="1">
        <location>
            <begin position="24"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="396" mass="43515" checksum="9912A182C7B9204E" modified="2014-06-11" version="1">MFKYVKAGLIAMTALFLGSAACAAPAYHVGIVTGTLSQSEDEIRGAEYCLKKYGDASKGGMIRHVTYPDNFMSEMETTISQIAGLADDPLLKVIVINQGIPGTTEGIRRVKQKRPDIICLVGEAHEDPNVITSAADMATTIDFIDKGYLLAYTAKKMGADTFVHVSFPRHMSYESIARRVAIIKAACKDLGIKFSYETAPDPTSDVGVVGAQQFMIEKVPAWIKKYGDKTVFFTTNYALHEPLLRQLARYGGMYIEADSPSPLVGYPAAFSIDLSKEAGNWPAILKKVESAVIKAGGKGRMGTWAYSYGYANTLALVDFGMNVVEKKMKLTSKKDFLKCFDRATPGSRWNGNYYTDLGTGVTSKNLMLIYQDTYIFGKGFMGVADVKVPEKYRKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIC9</accession>
    <name>A0A010ZIC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441841.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_561073_0_0_0"/>
    <dbReference type="OrthoDB" id="667830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="486" mass="54399" checksum="757F5D1B1142F190" modified="2014-06-11" version="1">MVEIEKFSAGIICGEDTLLLGNTERKNASIGKIIEMWPEACPDHALVVLDHKGRLYESFAGDALLADLSSEGSVIPDLIEPFAANEDIGAGSENIAYALRQAVYQEIKSRDANDKFFDDLGKLSTDRMLIYMLETAKNVVHNIAACASEEGGEGVVRLLARLNLFKIFCRQHRFIETLMTKTIGGESDTLPVKYRLKEAESKSGFITREFALAKYILDHELRFQKNGDRDAPVPFADLLFTNGDNTNTQRCIKMQADASTSDFRALITLMMRGSELFRGLETLKLGDYLASPEGRPLFVCSSGNTSADRGFAPLLIAALGAAARNTKRRAVILIPELDRWGLLNYLDKFRQSWDRLSFAFGYDNFSRLSLESRTGDDQLLETLYSASTQRIWHASEEERIGRAFGSYVSAADVIYRPEDLNEEIRAVEKEGRVSYSSLEESPPPSPVRKRARLRRSRQAAKLWITEGAARHEKLTLESLLEEGETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZII7</accession>
    <name>A0A010ZII7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441900.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.695"/>
    <dbReference type="HOGENOM" id="CLU_122734_3_0_0"/>
    <dbReference type="OrthoDB" id="1733128at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="121" mass="14298" checksum="743E950FAAB8FDF1" modified="2014-06-11" version="1">MAFEIIFYRDRQGREPVLEYIQALDGKKDKDSRINVNKIYDYLDFLSQVGTSAGEPYVKHLDGEILELRPLRNRLLFAAWNGSGFIILHHFIKKTQKTPRRDIEQAKRNLADYRERSDLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIM8</accession>
    <name>A0A010ZIM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/amide ABC transporter membrane protein 2, HAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.726"/>
    <dbReference type="HOGENOM" id="CLU_031365_1_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="354" mass="38561" checksum="D03F88C9BC30BAE9" modified="2014-06-11" version="1">MMKNSTKLTLNVICLGLLALFLWWAQDSLDGYKIQVLNLIAVNAILAISLNLIYGFTGMFSLAHAGFMAIGAYVTAILILPAAQKEMMYILEPMMWPFSVMHAPFFIAVVAGGLVAALVGLLMALPCLKLGGDYLGIATLGFGEIIRVLFTNMTPVTNGALGLKGIPAYANLGWNYFWCVLTFYVIVKLLSSNFGNTLRAVRDDEVAAKAMGINTFRTKTISFVIGAFFAGVGGALMGSLITTIDPKMFNFQLTFNILMFVVVGGLGSITGSLIGTVVITVLLEWLRFVEDSITIFSWEFAGVPGMRMLIFSLLLLFIILYRREGIIGGYEFSWDSAARLAKRIFRGKGARANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIP1</accession>
    <name>A0A010ZIP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441944.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.736"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_0"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="259" mass="27528" checksum="33966211F9BF1C28" modified="2014-06-11" version="1">MTHFLKDKRVLVTAGSDGIGKAIAAAFYGSGARVHICGRTAEKLERCREEMPGLTYSVADVASYEDVEKLFGDIKAGMGGLDFLVNNAGIAGPTGRVDEVTPEEWAHTMKTNIDSQFFCTKLAAPLLIAAGGGAIINLGSTASLFAYPHRTPYAASKWATIGFTKSVALELGEFKIRVNAICPGCVEGPRIEGVIAREAAKLGLTPQEVREGYLGQTALRTFIKAQDIADMCVYLCSPSGEKISGQSLAIDGFTENCHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ44</accession>
    <name>A0A010ZJ44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484875.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_3_0"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="256" mass="29335" checksum="630180E5BA4E046E" modified="2014-06-11" version="1">MKIGIPFEKKESKKKIVQDKLRELVSSGPFNEGDKLPSERELAQMLDVSRNVLREAVISMVAEGSLEVRERQGTFIKSLDSFGMHDSLKSLQMLPADFVSYQLEVRLIIEVPAAKIAAMRRTDNDIRKLRECYESFIACPYVTPEEQAQNGKWEALLHHLVTESAHNPILSRLNESINSLVERNNILVHPDMLMEKGWIELIKSRHAAIIRAIEEKNPEEAGETLKTHLLETAEVMRRTHPELITDIPSPYWKMNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJH5</accession>
    <name>A0A010ZJH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484889.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109798_1_0_0"/>
    <dbReference type="OrthoDB" id="1200741at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="179" mass="20619" checksum="80445C30DED2E22E" modified="2014-06-11" version="1">MLEEESMKQTLDIILPQILSEDTSFITIPHQGCGDLRISVENKLKSWRGDDMRFVIVHDKDNKDCRLLKQELAKICKPYNRKVLIRIACQELEAWYFGDLKAVSAAYGKNLSPLANKNKYRYPDNIRNPKELLRRLIPEHQQISGAKRIACHMDLSANSSASFNTFINGVRRLENTDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJI3</accession>
    <name>A0A010ZJI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar phosphate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442217.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_62_0_0"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="414" mass="45645" checksum="1E6384F915F043A4" modified="2014-06-11" version="1">MKEENILLTPLFMRLFIPFGVGYFLSVFLGSANATMAPILITEFALSPADLGFMGSVYLIFFGLAQFPLGVFLDRYGARVTLAPMLLFAVAGALLFAAAEGFAALVLSRALIGIGLAGSLMAAFKAYASWLTADKLPLVYSVQSLMGGIGGMFATRPVAIAFDIFGWRHVFVMLAVISLCSASLVWFVVPKDTVRRDERRGSFWKLLGKMFCFFADRRFWLVAPLVTAAQSVMFAYLYLWVGPWMLDVAGMDIGEAGMYMMLAFGGAALGYFGNGILAGWFKRKGWLSWEQLYLLSGVTLTAVLAAIMFMNGRGAAPLWGAVMFLSTMTMISFPIMRTMYAEDEVGRVLSLLNFTIFLFSFIVQWFIGVVLDLYPVSGGRFSPAGYRSSLAVVVIFNLASCIWYYYGMKKESSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJJ5</accession>
    <name>A0A010ZJJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710955.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1029"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="159"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="6"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="438" mass="46895" checksum="C5CD5C30D3D7B4E0" modified="2014-06-11" version="1">MIYIALIILIATLTIGVPVPVSFMASCAWLIFFGGPDGAGYQATQLLPYGFTQMNSVSLIAIAMFILAGGVMERGKIAEKLIDMVDVFVGHIRGGLGIVAVVSCAVFGSICGAACATLSCIGAIMFPRLRSGGYPMGHACALMANASLLGLLIPPNATLIIFAWISGISVLACFLSTVGPGIITIILLSLINVWMLRNNKEVFVEVKRTGKERMEMFMKRGRLAIPALVMPVMVLGGIYGGVMTTTEASALAVLYCIPIGLFVYKGLNWKTLFNIIVESAITTGVIMVMLYSVSMLSRLYILEDLPGRVLHLFYSISTNPIVVMMMINVFLVLMGMLMDDISVVVLTTPILLPIIMDLGFNPVHYAAIVGVNTALGCITPPAAPVLYLSGRVGGAPINEIMSPALKFMVLCWVPVLLVTAYIPKVVLALPHFILGVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJM3</accession>
    <name>A0A010ZJM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">Cloev_0994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711010.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1063"/>
    <dbReference type="HOGENOM" id="CLU_065464_1_2_0"/>
    <dbReference type="OrthoDB" id="1398618at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="90"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="180" mass="19247" checksum="7DEB0C75F43122C5" modified="2014-06-11" version="1">MSRIGRKAIALPKGVDVKIDGQHVTVKGAKGTLEMDVMPNIAVAIEEGLVHVTRANDDKPVRAAHGMTRALIGNMVNGVNDGFQKVLEIVGVGYRAQMQGKNLVLSLGFSHPVEVVPPAGIEFACESPIKIIVRGIDKQLVGQVASNIRGYRPPEPYKGKGIRYAGEYVIRKAGKAGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL16</accession>
    <name>A0A010ZL16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441233.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_695808_0_0_0"/>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_30" evidence="1">
        <location>
            <begin position="321"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="396" mass="44743" checksum="380312B626ACA5B1" modified="2014-06-11" version="1">MPEKDRDRFLRDTMRTALESGDIQRVLSLFRDWSGLDFAYIDARTKAICCTRGEPQFYEELQLYPVMELLRIYSAWEVTRQSCRLGWLVAASPAGSECACQAEAPFVADALAVCHLSKFTRCLADGGEESSFTAKLFAAKEEDEAYCLGMLREGGVELSKGFCAASFFSELGGPAEARLLERFRGIAEGAGVKFFVSGDERVKNFIIFHNGRGMRQTIVTNLITLWEHSAREGQISSEGRICWGWSGEGLSYGDIPRCLSQAFFVVKHGLIRGAVPPVLRWEELGLWRVFAALSESADFSAYAADCLKEIIKYDETHQSRLMMTLHTFVCHSWNLTAVSKELWLHYNSMKYRYNKIAALLGKNLDDPEVRFKLTVIFYIYAYSLSPLEYLNSARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL40</accession>
    <name>A0A010ZL40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL</name>
        <name evidence="9" type="ORF">Cloev_0081</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441263.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.95"/>
    <dbReference type="HOGENOM" id="CLU_016922_1_5_0"/>
    <dbReference type="OrthoDB" id="493793at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG77982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="430" mass="45372" checksum="E85ABC9FE45770E8" modified="2014-06-11" version="1">MSQSQCERLFEEARLVIPGGVNSPVRAFKSVGRTPVFAARGEGACLWDADGKKYTDYIGSWGPLILGHAYGPVVDAVCEAVRDGASFGLPTAREVEMARLITELVKGVEMVRMVSSGTEAVLSAIRAARGFTGREMIVKFEGCYHGHSDSMLVKAGSGLATAGQPDSAGVPAKTAAETLTCRYNDLEEIKNIFAAHRGEIAAVIVEPVGANMGVVPPAPGFLEGLRGITAENGALLIFDEVITGFRLSINCASGYYGVTPDLWTFGKIIGGGLPVGAYGGRRDVMSMVAPLGPVYQAGTLSGNPVAMAAGLAALTALRENPLIYKELAARGEKLRGGLDKIFKKYNIPACVQGVGSLATIFFTAGPVKSYDEAKKSDTARYARFWSGMAARGILLAPSQFEALFLCAAHSDEDIEYFLVCADETAGSEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL63</accession>
    <name>A0A010ZL63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mn-dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0106</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441300.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069532_3_1_0"/>
    <dbReference type="OrthoDB" id="2047422at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="120" mass="13567" checksum="9FA83CEC72E0EC4E" modified="2014-06-11" version="1">MQESGENYLETILILKNKNGSVRSIDVARELAVSKPSVSRAMGILKDNGFITMETNGELHLTELGRARADAIYERHRFITKFLAEVVGVSPQTAETDACRIEHIISQETFEKIKEYLVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM09</accession>
    <name>A0A010ZM09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441551.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1764842_0_0_0"/>
    <dbReference type="OrthoDB" id="1839196at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="147" mass="17131" checksum="20370EB5FAD3C383" modified="2014-06-11" version="1">MRKRKTEERIKAIEMHKQGIPRRRIAEELGVSHDSVKTWISLYKSGQKDLLDDTRKKRTYSKAVKLEAVSAHLEEGRTMVDVTSSFNISSPSLLRRWCKEFIEQGDISSSKQDCPDKKLEVTNSIEKIKELEMQVDVLKKALELQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM51</accession>
    <name>A0A010ZM51_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tagaturonate/fructuronate epimerase</fullName>
            <shortName evidence="1">D-TagA/D-FruA epimerase</shortName>
            <ecNumber evidence="1">5.1.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">uxaE</name>
        <name evidence="2" type="ORF">Cloev_0419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>keto-D-tagaturonate = keto-D-fructuronate</text>
            <dbReference type="Rhea" id="RHEA:51656"/>
            <dbReference type="ChEBI" id="CHEBI:17886"/>
            <dbReference type="ChEBI" id="CHEBI:59881"/>
            <dbReference type="EC" id="5.1.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UxaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.2.7" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441627.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.462"/>
    <dbReference type="HOGENOM" id="CLU_038563_0_0_0"/>
    <dbReference type="OrthoDB" id="647950at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016856">
        <property type="term" value="F:racemase and epimerase activity, acting on hydroxy acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02243">
        <property type="entry name" value="UxaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032586">
        <property type="entry name" value="UxaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16257">
        <property type="entry name" value="UxaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="496" mass="55614" checksum="ED4DD3A59C6A3625" modified="2014-06-11" version="1">MKSYLDYIKGGCAGRAEDFGIYPLSVNKIGDTAVMMAADGENDVIVTVGPSVGFVGERGSAAGREYTAAPLTWENGCVLRKLFPFTAPVRVLGAKRTFGAGDRLGIATPGHIRAIRRYDARPVFAQQSMRELTLTDRSYKDILDCASFAVFREGYRDGYGADGDHLKTADEIRGALSLGYSMITLDCCNQMHNDAESMTEAEVDARYAPNAEIEEKYLGRNFDIGEGVTLTFDAPSLKRMSLVYGDVIDYAAKIYFELFAPGKYDADFEISIDETTTPTSPLEHFFVANELCRRGVRFATLAPRFVGEFQKGVDYIGNLDELQKQMHVHAVIARHFGYKLSLHSGSDKFSVFTMYGRETRGNFHVKICGTNWLEAMKAAAIKDPALYREIHKFALEVFEGAKKYYHVTTDLSKVPDIDGLTDDELPELFTQNDARQLIHITYGPILTAKNADGSTCFRERLYTLWRKEREFYTEDIEKHVGRHLELLYGGMDGWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM87</accession>
    <name>A0A010ZM87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_390259_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="708" mass="77758" checksum="C4C63C7BB5E61AED" modified="2014-06-11" version="1">MALRVVKSDISTAKSASDAEQSKRTRFYSLYRARGDEGKSERSHRSTFTSSDVMNCIEWIMPDMMKAFAGSRKVIAVVPRGGEDVKKAEKIEKLLNWQFMHQCQGFLTLQAWIKAALVYGIGHLKTGWEEQYARKGFAQPEVIEPDFMQMVEDDSIESLSYLDSYEVPVPAQQARGMPNAASYGFSPAQVEMMRVYTDVQGEQKIKTYSGPKLEVIPPEDFLIDPEAKDVDSARFVIHRVMRTISYLREKERDGIYANIDRVVQLSGEGNNGDYDSTEEVARLQDSASYSAMGYTDDNEAQQIGRRKVDVFEWWGELDVEGDGRTESYLVVVCKNTIIRMERNPYAHGKSPFVDLLPIPDIFSYEGIGYAELAGPHQEVKTAVIKQLLDNASFTNNQMWEVDENAGVDVDALANPFPGKVVFTNRLGGFKAITPAQLDGSSYNLIEFSQGQLEQLTGVTRYNQGLDANSLNKTATGISAIMDASSKRKELIARTIAETGLRKLYLKMLQLDQQFIDQNIVIRLFNAPLEISPDDLAGNFDVSVDIGSAVTDDDTEVRQLFMMVQQYPMLQQLGIMRPGNVFTICKKVLDIWGYKNTEMYLSDPQETETARQAMVAIARLAQFVQGTGQVPPLQVIAEVLQAAYGALAKIAGPGPGGGIVNGEDGAPAQAGGGAPGHDGKFVPSVVASRYGGAGEAGGGLPAGGSQPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMB9</accession>
    <name>A0A010ZMB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0511</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709616.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.548"/>
    <dbReference type="HOGENOM" id="CLU_011781_2_4_0"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Creatinase_N" evidence="3">
        <location>
            <begin position="10"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="315"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24_C" evidence="4">
        <location>
            <begin position="540"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="599" mass="67189" checksum="779F46EFC7D41D21" modified="2014-06-11" version="1">MDFLGKLGVIREKMRGNGVGAVVLPSADPHQSPSVSAHWKTVQWLTGFSGSLAICIISADAAALWTDGRYLLQAQRELEGKDVEIYISSDPDAPDYTQWICGHIKDGETAVVDKSLISAAEYNSVSQKLALKNIKIDDYDDYVGEFWKERPPISREPLFELADAYAGVSRKAKAESVRAKMREKQADCYIASSLDAVAWLTNLRGGDNPIYPLFHSYLLFTEENIWLCAELSKVGADIAEKLKSDGFRLCGLNDIFALAAVETVGKRVYLDRYKTSARLCDSLPQKSSVVEGIDLITSIKSKKSEAERENIRLSNIKECVALCRLIKYIKENVGKSAMDEYGIGQKVNEFRAMDPLFMRPANVPIVAVSENAALPHYKPRQGASRAIEPNGFLLFDLCAHYYTGSTDITRTIQIGPLSDEMRRDYTNVLKAHISLATLVFPFGTTGFVIDGIVKSHQWRRRMNYDTGTGHGIGYCLDIHEGPCKIVSEFSPLFPYAMTVPLDVGMLFSNEPGVYKKGRFGVRLENNIMVREDCVNEFGRFLKFETLTYCPFERGAIVKEMLTEEELEWLNAYHRKTYVILSPCLNAEEKAWLKNETAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMD8</accession>
    <name>A0A010ZMD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441774.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.569"/>
    <dbReference type="HOGENOM" id="CLU_069356_34_0_0"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="218" mass="24939" checksum="B0ED65A6D3A97A7A" modified="2014-06-11" version="1">MGTKEKILVTALRLFAQDGYEAVSVSRIAGELGMTKGALYKHYKNKRDIYDSIVAHIFQLDAERAKTSKVPEKTFDETPLPFRYATVEGLKTFMEAQFRYWSEDETACNFRRMLTLEQYRNPELTELYHRAFTSGPLGYTEDLFREMMGRGLWHKGNPRQMAVEFYAPFYLLLSISDAALSEPEKRATAELFTAHVEGFIEKYASDGEEAADGGDHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMM5</accession>
    <name>A0A010ZMM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Pyruvate:ferredoxin (Flavodoxin) oxidoreductase, homodimeric</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0633</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441879.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.678"/>
    <dbReference type="HOGENOM" id="CLU_002569_0_0_0"/>
    <dbReference type="OrthoDB" id="10483at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037112">
        <property type="entry name" value="Pyrv-flavodox_OxR_EKR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000159">
        <property type="entry name" value="NifJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="678"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="734"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="968"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="997"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="697"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="743"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="746"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="749"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="753"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="821"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="823"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="846"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1077"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1177" mass="129353" checksum="62D462E5B12E48E7" modified="2014-06-11" version="1">MSEKKMVTLDGNEAAAHVAHAVNEVISIYPITPSSPMGEWSDQWSAESRPNIWGTVPLVEEMQSEAGASGAYHGALQAGALGTTFTASQGLLLMIPNMYKIAGELTSTVMHVTARSVAAHALSIFGDHSDVMAVRNTGWAMLSSATVQESMDNALIAQMATLEGKVPVLHFFDGFRTSHEEMKIEEIPYDAMRACIDDDLVREHRYNRLTPDAPFIRGTAQNPDVFFQSMEGRNRYYADMPDTVQQAMDKFAKTIGRQYHLFDYYGSPEAERVIIIMGSGAAVAREAVDRLNQEGEKVGLIIVRLFRPFDITRFTNALPGTVKKIAVLDRSKDPAANSEPLCADVKEALNGSGITIVGGRYGLSSKDFTPAMVKGVYDELRKLAPKDGFTIGIEDDVTYTSLPYDPSFDTENPKTVRCLFYGLGSDGTVGANKNSIKIIGQETDLYAQGYYSYDSKKSGGITVSHLRFGPDPIYASYLINKANFLACHVYSFLEKLDILKNAADGGTFLLNAPFGPEQIWDKLPKTYQQKIIDKHLKLYVIDAVKIAKQTGMGSRTNTIMQTCFFAISGILPQDKAIKAIKDSIIKSYTKKGQAIVDKNIKAVDETLANLYQVKVPAEATSAFDILPPVAEDAPEFVKQILGPMMIMEGDSLPVSALPEDGTYPSATTQYEKRNIAIDIPVWDPSLCIQCGKCVLVCPHAAIRAKVYAPEKLEQAPAAFRHAQAKFPNFKDYDFTIQTAPEDCTGCGLCAANCPINKTKAEDPHRPLIMRTQMPIRETEKANWNYFLSLPETYKAKLNTATVKDVQLLRPLFEFSGACAGCGETPYLKLLSQLFGDRAIIANATGCSSIYGGNLPTTPWAVNDQGRGPAWSNSLFEDAAEFGLGFRLTIDKHREYAAELLTKMTPELGEQTVREILDAPQTTGEQIKAVTDKIDRLKEQLCCIETQQAEELESVIDNLAKKSVWCVGGDGWAYDIGYGGLDHVIASGKNVNILVLDTEVYSNTGGQASKSTPRGAVAKFAAAGKRMGKKDLAMMAMSYGSVYVGKVALGANDAHTVKVFQEAEAYEGPSIIIAYCHCIAHGIDMVKGLDQQKKAVDSGHWMLMRYNPDLAKEGKNPLVIDSKEPSLPLEDYIYNEVRYKSLKATAPEEAAQLLEEEKKAIADRWRFYRHMAEMKMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMP1</accession>
    <name>A0A010ZMP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441895.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1913422_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="132" mass="15101" checksum="445B0622CB987881" modified="2014-06-11" version="1">MTTEIEERTNGMTEAETEATETETWDISDEEAEARAKHSNEGLADDYIYNIRSGIGQLTRDCEDPKIRVVLLNLLRFAEETYDQTLTPTVKEFSAEYPDGVELPNFARHFDILSSLESCTTDVYFPEDSRFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMT2</accession>
    <name>A0A010ZMT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0684</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441933.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.729"/>
    <dbReference type="HOGENOM" id="CLU_006187_7_2_0"/>
    <dbReference type="OrthoDB" id="305005at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458221" evidence="8">
        <location>
            <begin position="29"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="49"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="483"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="677" mass="75556" checksum="0E121AD2B55FC1C2" modified="2014-06-11" version="1">MIKSWTGAFKCALLFAAAFFCVAGSAEAAWVNSDIADFPAGAKAPSYRDDFHRAVNYEWLSTAKIQKGEMLVGSFSEREDEVETQGKKLLRDRSLKSHEAALVQKFHGMLRDWKSRGRLGMEPVLPYIKRIEAIRDLDGLTSYLTDVRDPHFGSVLFDICVTPDNKDATNNTVAIAPTGLLLMDADEYRAKELSDSAKRRKAANDIFIVKLLQKAGYDKARAEAMNDGLFRVEKKLAAQAMGRKELYSPAAQAALYNVRTKEELAKASTRFPLTAAVDSLGSGGSREFVLMQPKWLASLNDLYRPENLEDIKSYLIISTLFSTANLLDRETRGWSVERGNAIMGSSGAVPDEKYAYGMVSAYLGEPLGRLYAERYADPKTKARIEGFIAKVVGYYRNMLHGESWLTESTRNKAVIKLDNLTVRVSHPDKWEDFSALDFKDTKEGGNLVEAVAAIADFKRLRDIKLVNTKVDRSKWDVTPQTVNAYYSGSDNSINIPAGILGGVFYSPAGGEEELLGAIGMVIGHEITHAFDTNGSQYDEKGNFVNWWTEADREAFDERAKKISDYFSTIEVLPGVKADGELVISEAIADLGGISCVTAIGREVPGFDFAKFFKAYARLWRSRKTKEAEEYYLKMDIHPLSYLRTNVNVQQMPEFYAAFDVKPGDGMYLAPEKRIALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN57</accession>
    <name>A0A010ZN57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484872.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1874466_0_0_0"/>
    <dbReference type="OrthoDB" id="1949369at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="154" mass="17682" checksum="860FB63966439080" modified="2014-06-11" version="1">MAEKLAPLESLLVSASGREAGKWKSITFAMIAAYLLLTAVWQFSHEEVTQRALLNLFLGCCSVVVIKYEKLIYVSPLGFVKETHTWVSHHRELLPWNEVKYVTLTTRGSRLMALIEKDEIGWKLFFKKDDLPELKEILKKHAPKVPVNDISPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN80</accession>
    <name>A0A010ZN80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.867"/>
    <dbReference type="HOGENOM" id="CLU_028518_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="224"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="427" mass="48148" checksum="F76B507FB68D2F5B" modified="2014-06-11" version="1">MANIEERLDLNDIDLWKETEHDFTKSEDIKRKSLTFYQDVWRRFRENKTAMFSLVFIVLLTITAIFLPYFWKYTYSDQNLEYSNVPCRLELYEIPGTGVSFYVTNDYNVLQVSRNGTLGKMAENTGDDLMARQKSFVLDGKDIKVDYSQYFAAKKKLYSLRRSAERGDDVDLPSEERAFENMKRYIVTVDGKEVEPSLRVWNKSHIFGNDALGRDIFIRIVYGARISLAVGFATALVCFVIGVLFGGVSGYCGGRVDDAMMRVVDIINTIPTLLYVILLRVLFDSGGLFTIILTIGLTYWVSMARLVRGEVLSLKKQEFVLAAKSLGAPTGYILLRHLLPNIMGPIMVTITMMIPNAIFTEAFLSFVGLGVSAPVASWGTLCNDALEGLYTYPQQLLFPAAAISLTILTFNLLGDGMRDALDPKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNB2</accession>
    <name>A0A010ZNB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase superfamily enzyme, subfamily IA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442067.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.893"/>
    <dbReference type="HOGENOM" id="CLU_871344_0_0_0"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="327" mass="36657" checksum="9F0F7BB10B39B08B" modified="2014-06-11" version="1">MCIKEPFWSPAGASGFLLDWDGVIAETKLDFSGIREKYYGGRRAMLLEEAFTLEPEAREAMFKELAELEMAGAEGAVPVPGAFELIEWLNKNNVPYCILSRNLTEVIRRGAEVIGLDLPPRTWGRDNMEWVKPDPRALLAAAGAIGADPRRCVYVGDFLYDLQGARRAGMRAVLVQRDEPRWSCWADVVYPLLTGLVEALHSPEPVVPWEYREIYAKKGERWLHNAASFIFSVPGDPSPTTDCWLARAASLGVGGFYVDPEKIFTPDDWKKNPSFDTSAMGLKWSEVVSGFLAPRYPLARVVTECEAPLNAPKNSLDIMRFIERKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNC1</accession>
    <name>A0A010ZNC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamate-1-semialdehyde aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710803.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_2_0"/>
    <dbReference type="OrthoDB" id="493793at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="450" mass="50153" checksum="C3D3B47EC4AD6EF6" modified="2014-06-11" version="1">MYESFEKRSVKSKQLFDRAMKVFVEGANSPSRGIATCKPYPIYVRDGKGGRLFDADGNSYIDLMLGFSANIMGHGHPKIVEAVTRAIQGGSHFAACTEIEVKCGEKFLSMIKNADKVRFGNTGTEAVMMAVRLARAVTGKKKILKFEGQYHGWYDGLLANCHTRPVDTMGAKMDPVKMVEGSGIPQEHIENLVICPWNDLEILEKMVKCHKHELAAIITEPIMANVGVILPKKGYLEGLQRIAKENDVLFILDEVVTGFRYGNGCYQDMAGLNPDISTFGKALGAGLPVSAIAGREGYMQEMQWGKALSYGTFNSARLPMEVSYVNMTEMTKDDCAGYRHIHELGEMLINGSRQIIKDLGIPVIVQGYGPMLQYYFTEKEAINDVRDYAEFADKEKYQTFARKLLCRGLYVTSSNGLHHCPCLQHTKEDFAEALNIIEDTFKEMKSEGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZND3</accession>
    <name>A0A010ZND3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043516_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="484" mass="54527" checksum="77EF06A013D91630" modified="2014-06-11" version="1">MNDTQGLYRLIYRFYRTQIEGGQYQSGEPLPAALEISEIFDVSFSTARKALQALKNDGYIELSPGRTGTVCWNGKCGLNRSELYDRINAVADMYAAMNYFLPPSLSLGARYLDQEGQAKLALIIDEIENNNSGAIFEFTAFFIRLLGNPVLLHLICELDNFVYAAFSGGDVHLLIKNNKHPWTERIPAKLFYDIVNAAGAADYARTDALFHQLIDSCNKDMNIYLDSVGLENATGKIPFRWQVYMEQERHLYSAAVDLLYRINTGEFSGRWLPPIPELAASMGLSEITVRRTIKLLNSIGVTETVKRKGTRIYGSERARRAVKIDVGLFKSRFVSGLSLLHILAITIEDVSYEAFPSFTEDCVKELTDAIENDARRGMEFFTLGAAIAIICKSSKNTVIKEIYSQIKGRLVWLYPLRLIEIQGIVLDVFPRLSSDMAVSLREGRRRDFSRQLSELMTNVFFVAQSVLLQLGIKEAAKLRLPSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNS7</accession>
    <name>A0A010ZNS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylserine decarboxylase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_1022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442313.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1092"/>
    <dbReference type="HOGENOM" id="CLU_072492_2_0_0"/>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033175">
        <property type="entry name" value="PSD-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35809">
        <property type="entry name" value="PTHR35809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00164">
        <property type="entry name" value="PS_decarb_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="208" mass="23111" checksum="C81C7708E835D2B0" modified="2014-06-11" version="1">MKLARDGYPTIAALIFMTAGGGLISPWISACLFVPLCIVVWFFRDPERAPERALADGDFLSPADGKVVEIEESEHEYVGRAVKIGIFMNAFSVHVNRFPTDGTVKYIKYVPGKKWFAFAPKASEINERLYVGAESDHGRFLLVQIAGILARRIVRRVRMDDIVPIGGRYGMIKMGSKVDIYLPPEIMPNVKIGDKVFAGHSIIGVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNW2</accession>
    <name>A0A010ZNW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type (Unclassified) transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711172.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1139"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="249" mass="27847" checksum="F723AE4DBC8C49EC" modified="2014-06-11" version="1">MSQPIEEKAATLLRAEKLVKAFGGRRVVNEVSVEIKKGEIIGLLGPNGAGKSTTFYMIVGRILPDSGCVWLGDTQLSDQPMYQRARAGIGYLPQEASVFRSLTVRQNLDLVLEESGVPRDVRGDKISRLLKEYGLSHLEDTKAVSLSGGERRRVEIARCLALEPLFILLDEPFSGIDPIAVADLQSIIRELKERGYGILLTDHNVRETLSITDRAYLIYEGKVFLEGKPDYITENKDARKFYLGEDFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7D1</accession>
    <name>A0A011A7D1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3198074_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="45" mass="5013" checksum="5B7D48B23931950C" modified="2014-06-11" version="1">MSGNEIFWQSGTWMLFAGQALVLVLIVALYFYMGKKEKEAGKKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7I3</accession>
    <name>A0A011A7I3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709189.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.125"/>
    <dbReference type="HOGENOM" id="CLU_012893_0_2_0"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="438" mass="46569" checksum="9EE0AB2048BD0A3B" modified="2014-06-11" version="1">MRGKLFMSFIKYVSQSVMGMVGISCYILADTWFVAAALGAEGLAALNLAIVFYSLLNAAGLMAGIGGATLFSLSLSSGRRGRSEIFSATVILGSVLAAVFTAAGLFCSGWIARTLGADEAIFAMTETYLRTILSFSLFFIMNNILLAFVRNDGGPRLAMAAMVTGSLSNIALDYIFIFPFGWGIFGAAFATAIAPMISIALLSLHFILRRGSFSLSFSRPRGVYILKMIPLGLSSMVTELSSAAALAAFNLIILAMAGNTGVAAYGVVANLALVELAVFVGIAQGMQPLVSRRRGMGDLAGCRALLCYGALFSLGAASLAYGAVFVWAREIAALFNQAGDRLLAAYAEEGLRIYFAGFFFGGLNVVTAAFFSAAEMPKRGFLISSLRAFLLALPLAALFSRFFGMRGLWFSFVAAEALTLFIAAAMLRRFAANFQREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7L4</accession>
    <name>A0A011A7L4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRAP transporter solute receptor, TAXI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709240.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.160"/>
    <dbReference type="HOGENOM" id="CLU_033215_4_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459429" evidence="1">
        <location>
            <begin position="28"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="326" mass="34826" checksum="8A23EE8502226C43" modified="2014-06-11" version="1">MKKFFTVLALVAVIFSVAGFAAAPAQAAQKLDLAICGGSIGGAWAAIGEGVGEVVRRSYPGSNTAYEVGQEAANLALVSRGKIQLGIAHAQLIKMAADGKQPFKKKIDNLRALCVLYNGAVEHFIVKADTKANTFADLKSKKYPLKAYFNTKDSFMDIVGKKVIEAEGITAADIDKWGGFTKNSSMGAALDLMRDGKIDAYSNVIQVPSSHVVDAGTTLKLNLLGMSPAAQKKVNDELGTYSAVIPKSAYNFLKNDVPTVGATVILFTNADLPDDEAYAILKSIKDNFPYFCNIHGSLKGLKFSEIKNTAPVPLHPGAVKFFNENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7L9</accession>
    <name>A0A011A7L9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709249.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.165"/>
    <dbReference type="HOGENOM" id="CLU_052511_3_1_0"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="162" mass="17423" checksum="FBA35A5A07EDEE4A" modified="2014-06-11" version="1">MQELKCVVNGKDIAIMIDPSHSLADVIRYDLGLTGTKKGCEEGECGACTVLVDGLPVDSCIVPAMKAQGRSILTIEGLEQNGELDPIQEAFVEAGAIQCGFCTPGVVLSAKALLMREENPTKEEVRDELSGHFCRCTGYLQFYDAVRIASEKIAARKAATKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7N0</accession>
    <name>A0A011A7N0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Small-conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709273.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037945_1_1_0"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006686">
        <property type="entry name" value="MscS_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01246">
        <property type="entry name" value="UPF0003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="272" mass="30056" checksum="EEC6BB496E972CF1" modified="2014-06-11" version="1">MNINLEGLPAMLEKVTFASLLPALLYLMGGLLIVKIVMGALTKALERSGIEKTLHKFVLTLIKLTLYFIVFMTVAGALGIQITSFVAILSVAGLAISLSLQGVLSNLSSGVMLLSVKPFKVGDYVEVGGVGGTVREIGFIHTKVSTVDNKIIYIPNSEVSSSKIVNYTNEDKRRVDFVFSAGYDCPVETVKLAIREAIEKFPQVFAEPAPFVRVGAYKDSVIEYTVRLWCKTDDYWNLYYDIMEAVPESYAKHGVEMSYPHLNVHMVNDQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7T9</accession>
    <name>A0A011A7T9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709376.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025443_5_1_0"/>
    <dbReference type="OrthoDB" id="1690667at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="155"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="379" mass="42457" checksum="13E1720CCDB48BF9" modified="2014-06-11" version="1">MNDRVFERRFSEHPAFWAACAAIVTVIYIYIFLTINEAQPEGTAGVIWLMLCFAMTGLSYLARRTKRLHHAQLRRWTDRAGSLWLLFVLYAFFTLIALETAGRFLGGGLPAWAELAASFALSLCLIALGVKQAHTIQTTKITVETEKLPPGEERLRIVQLTDLHLGPYTGVKLLAQILRRVREADPDMVLVTGDVADGSLEGRGREIAMFRRIRPKYGVYAVTGNHDYYDGIDKALEFMRRAGMRVLRGESVCAGGIVVVGVDDRDHLCEDKWGLSRSETVIVNTKSRFRDKFILLLRHRPVVEIGTQGLFDLQLSGHTHGGQLFPIISSRLFFRGHSRGFKKLKNGSMLYTSNGAGYVGPPVRLMAPPEIVVIDLVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7U5</accession>
    <name>A0A011A7U5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cloev_0227</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.247"/>
    <dbReference type="HOGENOM" id="CLU_091705_2_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="11">
        <location>
            <begin position="37"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="147" mass="16246" checksum="D6729D245671F31C" modified="2014-06-11" version="1">MRDHNKKLMKKRRGFTLIEIMVVVVIIGLLSALVGPRLMGQSDEAKRKTTQTQIAQLEQVLGLYYLDNGFYPTTSQGLEALVKEPTMPPEPLNYKKGGYMKKVPKDAWGREFVYTAPGEHGDVDILSYGADGQEGGSGANADIANWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7V2</accession>
    <name>A0A011A7V2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP-type C4-dicarboxylate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441409.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_1_2_0"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458578" evidence="2">
        <location>
            <begin position="24"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="334" mass="37688" checksum="257ED6636D9A1684" modified="2014-06-11" version="1">MRCLKNILCSLMLLALISSPSAAAEVTLRFAGQFPEEHSATKLMREIAEGVRTRTRGRVNIEVYPDNLLGDYTIIYEDLMRGAIDMALISIPSHFDPRLELVYLNAFVDHNVVRRNVRLDSWLSQKMDEYNTRLGVKLLGFNVEGLTGIASVKPINSPLDPKADKGLLVRIPPMHVYKSAIEAQGYRTVTMPYADTARALQEGRCDAVSSISSGAALANLKGIMKYWYQLNYSQAVESYLMSAKTWDRLSEGDIAVIYGEVARASAKSFEQAKHNNKRNLKRMRQSGIRVFTYSDAELLPLRRAIVENWKGLEPVMGRQLMNDARKHFLIDAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7Z9</accession>
    <name>A0A011A7Z9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0273</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441445.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.297"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="310"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="427" mass="45574" checksum="46E845DECDF99A23" modified="2014-06-11" version="1">MFILAAALIIGISIAVPISYSIAVSGTLYLLFESALPVLVIAQRMVVGADSFTLLAIPLFLLAGALMAEGDITPRIMRFASSMVGHIRGGMAMVMVVSCMFFGAISGSGVADVAAIGSIMLPAMKEQKYRPAFSASLLGCGGALATIIPPSIVMVILGVTMGTSIGKLFIAGFIPGIMAGGSLMAISYYFASKENYPRLPKTGAREKWEAFKGAFLPMVTPAIIIVGILQGIFTATEAGGVAAFYALILSKYVYRKLSWRRFFEICLEVAKTSAVVLFIISAASLFGWILTSQDIPQKIAEAILGVSNNYWVVLIFFNLMLLALGTFMETTAIILIVIPIFMPIMTQIGVDPIHLGVMVCVNMAIGANTPPLGVDLMTACKVADIAYEDSFRYIFFFLAAMTLVLILIIAFPQLSTWLPNMVVSSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A835</accession>
    <name>A0A011A835_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="6" type="ORF">Cloev_0299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a complex with TatA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484803.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.326"/>
    <dbReference type="HOGENOM" id="CLU_031942_3_3_0"/>
    <dbReference type="OrthoDB" id="1848013at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="243" mass="26632" checksum="7BC94EEC74298A76" modified="2014-06-11" version="1">MTNDHEETLAPHLEALRDALLRCAAATAVLYPVGYLASPYLINALVRWCFPESAGTLHYFAPMEVLWVRLRLALIAALLAAYPWNILQLWRFLLPALYKRERKALGCCIVSSSLLFFCGAAFSIGLILPLMMNFSGGFATAELRPSIGLANFLNLAGWLTLAFGVMFQSPIIVLLAVRFGVISCGSLRRKRPYIATAILIAAAILTPPDIVSQLMLAIPTWLLFELGLIIAGRIEARESVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A861</accession>
    <name>A0A011A861_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type Co2+ transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441498.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.351"/>
    <dbReference type="HOGENOM" id="CLU_052508_0_1_0"/>
    <dbReference type="OrthoDB" id="1632785at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025937">
        <property type="entry name" value="PDGLE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13190">
        <property type="entry name" value="PDGLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458287" evidence="8">
        <location>
            <begin position="26"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="PDGLE" evidence="9">
        <location>
            <begin position="236"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="340" mass="34516" checksum="9B5126E34ADB38A9" modified="2014-06-11" version="1">MHMSDALLSPSVAFAMCAASGAAIAWSVAKIKKEELSEKKLPIMAVAGAFVFAAQMINFTIPATGSSGHIGGGILLAALLGGAPALLTISAVLVIQCLFFADGGLLALGSNIFNMGVIPCLVIYPLLFKPLMKKGTASGRLTLASVVSVVVALQLGAFSVVLETLASGITALPFSSFVLLMQPIHLAIGIVEGLVTGAVLSFVWKTRPEILESAESGDDIPAGVPLKKVLAMLAALTLVTGAILSGFASSYPDGLEWSVMGVTGSEELEASGGAFESAAAIQEKTAFMPDYDYAEPAEGAPVSGTAAAGIIGSLMTFAAAAFIGAVISKSKRHKKAAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A896</accession>
    <name>A0A011A896_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0351</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441546.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.383"/>
    <dbReference type="HOGENOM" id="CLU_001771_6_2_0"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="655" mass="68896" checksum="8ABB4666B38509D4" modified="2014-06-11" version="1">MEHRHEIEHDHEHEEAHCCGHCHSREEGGGIKGTLIQLFAAFALAAAVAFAPLPPYAKAAGFAAAYLIAGWKVLLSSLRNIMKGEIFDENFLMSVASLGAFAIGEMAEAVAVMVFYGVGEMLQDSAVAKSKRSIESLMDLRSDRANVLRGGKTVAVSPEEVMVGETISVKPGEKIPLDGVVLSGTSFLDTRALTGESVPRRAAPDDEVLSGSVSTDGALEIRVTKPFSESTVSKILELVRGAASKKSATERFITKFARWYTPAVVGIAALVALLPPLAGYGTFAAWFYKALSFLIISCPCALVLSIPLSFFGGIGGAARSGILVKGSSYLDAMSRLGTVAFDKTGTLTRGVFKVTELLPAEGVSKEELLRRAAEAEAQSNHPIARSIMAAFGGEAPERSDARELAGKGIEARVKEGTLYAGNTKLMKDIGIGGLRGYAKTAVHVALNGKYLGALLIANELKPGVRAAMNDLRAAGISRLVMLTGDNAAIAKETAAEAGIDTVRAELLPQDKTAELEKLMAGEEKKTAFVGDGINDAPVLTRADIGIAMGGIGSDAAIEAADVVIMTDEVDKIATAVRIAVKTKRIVWENIAMALGFKVAVMLLAIFADASVWFAIFADVGVALLAVANALRALKAPAPRNAAMERERGTEPCPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8C0</accession>
    <name>A0A011A8C0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein encoded in hypervariable junctions of pilus gene clusters</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709033.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_198435_1_1_0"/>
    <dbReference type="OrthoDB" id="2062091at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005569">
        <property type="entry name" value="Arc_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03869">
        <property type="entry name" value="Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arc" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="62" mass="7214" checksum="65F7F8E83A578520" modified="2014-06-11" version="1">MWKIQKGSTSVSRTFRLPEEMVEVLESLASENRLSLNQLVIQCLRYSLEHLDPPEETAPKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8J0</accession>
    <name>A0A011A8J0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709143.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116722_4_1_0"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="46"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="144" mass="16490" checksum="B52B2A3A4EF8A905" modified="2014-06-11" version="1">MSEEKNYGSIYDLPLQNASALAPEIEKRTIYGPENCWGDYVMRHFILPAHKGIPAHEHEWDHLMFTLSGDGVVEVEEEPGKRVPYLMKTGYWTRVPGGLVHEYKNDADVPLEFFCIVPTRGDPHAKKFSMREERAQRKACEGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8K9</accession>
    <name>A0A011A8K9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441691.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.503"/>
    <dbReference type="HOGENOM" id="CLU_014695_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="467" mass="51251" checksum="C450871284986314" modified="2014-06-11" version="1">MGLIIDLFAGGGGTSLGIERALGRSPDIAVNHDPEAVAMHKANHPHTKHYCENVWAVNPREATAGRPVDFLWASPDCKHFSKAKGGKPLDKKIRSLAWVIVKWAAWTRPQVIAMENVEEFRKWGPLDRKGRPIKALEGTTFSNFVFALRKLGYKVDYRDLKACDYGAPTSRKRFFLVARRDGAPIVWPVRTHGVGTGRPYRTAAECIDWSIPCPSIFEREKELAQNTLRRIAKGLVRYVLSNPSPFIVSVNHGGDAFRGVGMDEPMHTLALDGPLMVVDANPRYAICAAHLAKHYGGVVGQAVESPVGTITAADHHSLVACTLMRQFGTSTGAPVDRPVGTVMPEGRGKTGLVAAFLTKYYGAEREGMQLNGPLHTICGKDKFAVVTVSIGGEEYAVYDIGMRMLQPRELFRAQGFGDDYIIDLIYEGKYLSKSAQVRMVGNSVCPPIAEAIVKANCAFMQEEREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8L3</accession>
    <name>A0A011A8L3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3097350_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="51" mass="6072" checksum="9AF0A9C5317ED222" modified="2014-06-11" version="1">MSNMLIYLLAWLCVNALLYLFAIWKEAGVLEYVAIFVFMITSVPWKQWPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8M2</accession>
    <name>A0A011A8M2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441711.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069778_0_0_0"/>
    <dbReference type="OrthoDB" id="1461352at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="347" mass="38660" checksum="55EC186D27608F04" modified="2014-06-11" version="1">MFNVARRLNLSFFEVNTRNFPTEIKNFYDRVALTTALPFLPFRKWGQKRPLPKNKGKVISFRRWGVLAPATTPLTEGITPTGSSLDYETITATVQQYGDWIPLTDQVQDLAIDAVLTQVVQQLGEQQGETLAILARNQMVAGVNVSYANKVTSRSEVVARVSADDYDRIILKLKMKLAKRHTEIIMPTVKIETKPIRAAYIAIISPYTTVELERQLGNGYVPVANYASGVGVMEGEVGSYKEIRFIETTHAMVYEDAGGNVADGCKSTSGTKTDVYADLIFGKEAYGETMVGGKDTHTVIIKMHKDDDTSDTSDPLNQRGTAGWKDYYVAKILNDDWIVRYEHAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8P9</accession>
    <name>A0A011A8P9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709615.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.547"/>
    <dbReference type="HOGENOM" id="CLU_705475_0_0_0"/>
    <dbReference type="OrthoDB" id="703457at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024258">
        <property type="entry name" value="DUF3798"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12683">
        <property type="entry name" value="DUF3798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458433" evidence="1">
        <location>
            <begin position="19"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="397" mass="43833" checksum="1FF063982873E00F" modified="2014-06-11" version="1">MKKSALLLVVSLFLFASAAASFADAPFHIGIATLTVSQAEDTYRGAEYMVKKYGDTSSGGMIKHITMPDNFMQEMETTISQIAGLADDPKIKAIVVVEAIPGTTEALRRVKEKRKDIICLTGSPQEDPNVISSVADYSVASDKIIRGYLNIYAAKKLGAKTFVIISFPRHMSYELQARRRAIFEEACKDLGLKYVFETAPDPVSDVGVAGAQQFILEKVPAWINKYGKDTAFFCTNDAQTEPLLRQVAKYGAIFIEPDLPSPLMGYPGAFGIDLKKEAGNWPAIMDKVEKTVIAAGGKGRMGTCSYSQSWATVCALTEYGKQIVEKKAKLGKPKDLLECYDTYTPGAKWFIRPYTELGTGVTNKKYQLIYQDTYIFGKGYLKLTSVKVPEKYLNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8S3</accession>
    <name>A0A011A8S3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycine betaine/L-proline transport ATP binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441782.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.574"/>
    <dbReference type="HOGENOM" id="CLU_000604_2_2_0"/>
    <dbReference type="OrthoDB" id="1713578at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031460">
        <property type="term" value="P:glycine betaine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005892">
        <property type="entry name" value="Gly-betaine_transp_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01186">
        <property type="entry name" value="proV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="32"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="393" mass="43470" checksum="C2EE806BDB3AB5F3" modified="2014-06-11" version="1">MVSPEIILEARSLSVIYGSSKREAVRMMEEGSDKAGVYSKTGATVALWDVNFQVKRGELFVIIGLSGSGKSTLVRCFNQLLRPTSGHVLFEGREIDSMKKKELLDFRRDKVSMVFQHFGLFTHRSVMDNVAYGLEVRGIPPEERRAKALEFIRMVGLDGWEDKAISSLSGGMKQRVGIARALANDPEVLLMDEPFSALDPIVRREIQFEFLQIQRKLNKTVLFITHDIDEAFKLGDTVAIMRDGRIIQVDTPEEMSANPADDYVRAFIEGADRSQVLTAKNIMTVPACLIRARNDPAGAIREMSHGNLSSAYVVDDRMRLVGVIPMDAALKCLRDKTPLSEAIEREPVTTTEDTLLSDIIPLAAGTRYPIAVVDSDGVLKGIVSRAAVLSSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8X8</accession>
    <name>A0A011A8X8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441843.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.634"/>
    <dbReference type="HOGENOM" id="CLU_036805_2_0_0"/>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="413" mass="47508" checksum="D3AF679822845391" modified="2014-06-11" version="1">MAKDKKITHKVQMTDGKRDIIRYLLQEYDIKSAKDIQDALKDLLGGTIKEMMETEMDEHLGYKKSQRSEGSDYRNGYKQKHVNSSFGEFSIDVPQDRESSFEPKIVRKRQKDISEIDQKIISMYAKGMTTRQISATIQDIYGFDVSEGFISDVTDKIMPQIEEWQNRPLSEVYPIVFIDAIHYSVREDNAVKKLAAYVILGINSNGIKEVLSLQVGENESAKYWLTVLNSLKNRGVRDIFILCADGLSGMREAVESAFPQTEYQRCLIHQVRSTMKYVVEKDRKEFAADLKTIYQAPDESHALEARDRVAEKWGSKYANAVKGWERNWDTISPIFKFSCQVRKVIYTTNAIESLNSSYRRLNSQRSVFPSAGALLKALYLATFEATKKWSMPVRNWRSILGELAVMYEGRMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8Z6</accession>
    <name>A0A011A8Z6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441866.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.660"/>
    <dbReference type="HOGENOM" id="CLU_022936_2_0_0"/>
    <dbReference type="OrthoDB" id="735109at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002823">
        <property type="entry name" value="DUF112_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01970">
        <property type="entry name" value="TctA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="501" mass="53159" checksum="9863999B8AB8B2D8" modified="2014-06-11" version="1">METIQLLLSGFSNAMTPINLIWLVAGSALGTVLGMLPGLGPTTGIALLMPLTFTMAPDTALVTMCAIYYGAMFGGSRSSILLNVPGDGAAVASCFDGYPMSPSGQAEAALAISAIASFIGGLIATIAFVAVAVPVARFALKFGPPEYFMLMCFALAATAAISKEAMLKGLLSMCLGLMIATVGIDPQSGAIRFTFGVTALQTGIDFVVVIIGVYGLGEVFHNMDHIRSDVAVKVQSKFGRIWVTMAQFKRCWWPMIRQTPVGFFVGVLPGAGATIAALMAYNNEKQLSKNPENFGKGEIVGLAAPEAANNACSVGALIPMMTLGVPGSGTTAVMLGALMILGLQPGPLLFQQHADIAWTVIASMFLGNVACAFINIPLASLLVRVLAVPTKILYPLIVAMALIGVYTINFSVVDFVLLVIFGLVGYFMKKYKVPTSPLILAVVVGVSMEQSYRQSMMLSDGNFAILFRSPICWVLFFLTIFSIVWPFFSDWKKKRKSAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A942</accession>
    <name>A0A011A942_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-oxoacid:ferredoxin oxidoreductase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441918.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.713"/>
    <dbReference type="HOGENOM" id="CLU_048564_2_1_0"/>
    <dbReference type="OrthoDB" id="981516at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="54"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="248" mass="27645" checksum="0620DCBBECAEB1D6" modified="2014-06-11" version="1">MTEKIIYKRPKSWVKGVHTHYCPGCTHGIVHRMICEVLDELDIQQETVGVAPVGCAALMYGYIDTDFIEAPHGRAPAIATGFKRIRPDRVIFTYQGDGDLASIGAAEIVHAANRSENITVIFINNAIYGMTGGQMAPTTLIGQRTTTTQDGRDPQKAGYPMRISEMLSTLASPMYVERVCAARHAYLPALKRAIRKSFQNQLDNKGFSFVEVLSTCPTNWGLRPKEACDWLVENMIPYYPLGVKRDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A971</accession>
    <name>A0A011A971_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0704</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710563.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_3_6_0"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="168" mass="19800" checksum="CC6F842B7C33AD62" modified="2014-06-11" version="1">MTIKKFLDNFEEYFCVWTMAIMTLLVFVQVVMRYVFSNSLSWSEEMARFIFLWLSWIGASYAVKERSHFRVEMFANMIPGAARRYFEYFVLIVWFVFSFILAWIGTELVIFIADTGQRSAAMELPMTWPYASVPIGCLLMCVRLLIEMYKLWKGEPLGPQNDNIEEVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A980</accession>
    <name>A0A011A980_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0714</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.763"/>
    <dbReference type="HOGENOM" id="CLU_045498_2_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="259" mass="26677" checksum="79285809AABBB9BF" modified="2014-06-11" version="1">MAAGFDISTMSLILVCFLVFLAGFVDASAGGGGIISLPAYIFTGMPAHLALGCNKFSSSCGTTLAVFKFWRGGAVNLRAAAIAAVGSFIGSAVGAKTALMLSDQTIKTMLLIILPCAAVVIFLKRNLGDSDDSAQMGRDKAAAIAFMIGLLIGGYDGLFGPGTGTFAIMAFSSLMKFDLKTASGNAKILNLASNYASLITFAFAGTIMYGVAIPAAVCGIAGNYLGAHCALTKGARFIRPMMLAVLALLLLKLLWDILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9H2</accession>
    <name>A0A011A9H2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium ion-translocating decarboxylase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0804</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710733.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.855"/>
    <dbReference type="HOGENOM" id="CLU_036168_0_0_0"/>
    <dbReference type="OrthoDB" id="662061at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015658">
        <property type="entry name" value="MmdB_OadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR015658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="374" mass="38935" checksum="FB3FF385ECF64225" modified="2014-06-11" version="1">MELYMTALRGVVEQSGFVALNGPTLVMLLVSFILLYLAIAKGFEPLLLMPIAFGCLLVNLPLSGIVDPGGFLYFVKIGIDHELYPVIIFMGIGALTDFGPLLANPITFLLGAAAQIGVFFAVIGAMFMGFTIQEAAGIGIIGGADGPTAIYLCAKLAKGILPAVAVAAYSYMSLVPLIQPPVIKLLTTKKDRSIKMEQLRPVTRTERILFPIVSTIACGLVLPASVPLVGMLMFGNLMRECGCTERLSLAAQNEVLNATTIFLGISVGATMSADSFLTVATIKIIALGLIAFVFSTAGGVCFGQIMKVVSGGKINPIIGAAGVSAVPMAARVCQKVVSKEFPGSYILMHAMGPNVAGVIGTAVAAGAMLTLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9H6</accession>
    <name>A0A011A9H6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710742.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157874_1_0_0"/>
    <dbReference type="OrthoDB" id="1937865at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009664">
        <property type="entry name" value="Ppnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36540">
        <property type="entry name" value="PTHR36540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06865">
        <property type="entry name" value="Ppnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="104" mass="11793" checksum="7068D51362F7779D" modified="2014-06-11" version="1">MADFINSVDVKTLVNIYCDGKVQSRTLRYPDGKLQTLGVYLPGEFEFHSEGPEKVIMTAGAVEVLFPEDNDWRRVETGECYDVPADTMFKVRCGVISEYICDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9K0</accession>
    <name>A0A011A9K0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442056.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.882"/>
    <dbReference type="HOGENOM" id="CLU_001771_6_2_0"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="680" mass="72028" checksum="D0F94C75BB108812" modified="2014-06-11" version="1">MNHEHHHEHDHECCGHDCRDPECGGRHENTAHHVHGHDSGCGCASCHALDDIFSENEVDEREQRASFRREITFLAAAGAIFLAALVLEELAPEIMPEWLFSAVFIALYLATGVPVLKTALKALFKGDVFNEFTLMGGATLAAVAIGEMSEAVGVMLFYRLGEAFQERASSNSRRSIKALLAQKPLTARIVAGGRIVERDPKEIVKGDVVQVLPGEIIPIDGHVISGVSQIDASAITGESMPTTASPGGEVHGGTLSLDGLLLVEAAGPFEDSTIARMLEMVQNAVERKSPTERFITRFSKWYTPAVFFLAAAVMTLPPLTGYGTWHEWIYRGLVLLVISCPCALVISIPLGYFGGIGAASKNGILVKGANVFDAVGSVDIAIFDKTGTLTYGRFKLAKILPAPGVSETELLETAALAENGSTHPVAKSIMAAAGERAVPPGASITQIPGKGMVCRLGEDTVASGNAALLEDFGVAVPEIDEHGTIVHVMKNGRYMGSMAVADSIRPEAAATVAELRRLGIKGVYMLTGDREDTAESVAKELKLDGYKADLLPGDKVDALKDICRGDTKKTIYVGDGVNDGPVLVTSETGIAMGGFGSQVAVEVADAVILDDSPAKVADLLRIAKKTRAIVWENVVMALGVKGIFLIFGVAGLAGLWEAVFADVGVALLAILNSTRATRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9L6</accession>
    <name>A0A011A9L6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.897"/>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="215" mass="24104" checksum="6325EE9AA35E08EE" modified="2014-06-11" version="1">MNAGYQTMGCTAVDCIYSGIRKKIISKELQKGQRLAETVIAKEFNVSRTPVREAIRRLANDGLVNIVPGWGAHLVSPTKEEVIDTSMMRQVLEEIAIRKAVQAVTPVYIYKLQEQILLEQKAAAECDVDAYIAANNNFHLVIAEASGSKTLFELLEHVLAKVVTHLLFFDDSLFKFDTNPTLNQHKEIVRALESGDVDLCVKLIKQDIYPWSSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9N0</accession>
    <name>A0A011A9N0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ATPase (AAA+ superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442079.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.912"/>
    <dbReference type="HOGENOM" id="CLU_039512_1_1_0"/>
    <dbReference type="OrthoDB" id="1657201at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008533">
        <property type="entry name" value="DUF815"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05673">
        <property type="entry name" value="DUF815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="230"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="427" mass="47974" checksum="B7B69651A6603A48" modified="2014-06-11" version="1">MIRELIPYRDFERDEVFACVTGLIKSAGQIDDSSLAESASWYCDCVAKMAAAAEKAGIAGNLWQTWLAMLVAENENPFSLAHERREPLDGTMRSLAMRDFETLYDYMHYDLRAVEAELGLGASGCLDGFVPMEAGPVSFGRIAGAVVGGLAEAMAKADSPAGLYEAAAAFYREHGVGKFGIYGGFRWDAHSREIVPAIPLEDIALSDLVGYEEQKKAVVDNTAAFLEGRPANNVLLYGEGGTGKSSTIKALLNEYAPRGLRMIEVYKHQINDLETILEEIKLRNYKFILFMDDLSFEQFEVEYKFLKAFIEGGIEKRPDNVLIYATSNRRHLMKETWGDRLDKDDDMHESETMQEKMSLVDRFGLLIRYFSPEQGEYLHIVRSLAVEYGVELPDEELERGAIRWELKHGGFSGRSARQYVEFLAGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9X5</accession>
    <name>A0A011A9X5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ammonia monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442234.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112829_1_0_0"/>
    <dbReference type="OrthoDB" id="1727872at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007820">
        <property type="entry name" value="AbrB_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38457">
        <property type="entry name" value="PTHR38457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05145">
        <property type="entry name" value="AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="164" mass="17358" checksum="899EC18109353182" modified="2014-06-11" version="1">MSSQFYTIFAVALGSGLGYKLNFPAGAMVGGLLGGLIVKGAFTMGLDPKIDWLSYLSQALVAYVLVRGSDFSSLRELPKYLPAAIAYSLLLLAFTLGLAWLFAHFCKMDFLTSLFATTPGGLTGIAVVAVDIGANPAISVLFNICRIVTVLVVVPILANIIVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9Z3</accession>
    <name>A0A011A9Z3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoB</name>
        <name evidence="15" type="ORF">Cloev_0971</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442276.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1041"/>
    <dbReference type="HOGENOM" id="CLU_000524_4_3_0"/>
    <dbReference type="OrthoDB" id="9601at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="12">
        <location>
            <begin position="29"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="150"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="291"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="13">
        <location>
            <begin position="453"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="14">
        <location>
            <begin position="532"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="9">
        <location>
            <begin position="661"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="10">
        <location>
            <begin position="1055"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXG78826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1226" mass="137484" checksum="2807221966F01D58" modified="2014-06-11" version="1">MQVKQTSGKAFERRVVFGKEKNLIALPDLVEVQRNSYQWFFQADREPDMRASQGLQELFDEIFPIESYDGSFALEFVRYYVDPVPISLDEARSRDLTWSRPLRATIRLINKKTGEIKEEEIYLGDFPAMTERGTFIINGTERVVVNQLARSAGVYYSADLGIPGQETFVAKLIPDRGAWIEFDLAPGDVLSVKIDNRKKIPVTMMLRAFGIQSTDEIISLFDGKEVEKDLVDDDVRGMLLAEDIVANDGSGAVEIRKNTRLTKEHMEVLWNHGRTKVWVWDIDPALAVTIERDNTDTPDAAMLELFRKLRPNEPARMENAREYITSIFFDSRRYNLGRVGRYKINRRLQLELSNSERLLTVTDIVAIIKGLIRLRDGSEHMDDIDHLGNRRVRAVGELLQNQVRIGLLRMERIARERMTTTPDLATAMAKDLINVRPISAALREFFGSGQLSQFMDQTNPLAELTHRRRLSALGPGGLSRERAGFEARDVHHTHYGRVCPIETPEGPNIGLVTSLATFARINDYGFLVCPRRKVVDGKVTEEIVYLSADDEDEYYVGRADLPMDDEGNVLPSSTGGIYVRHHDNTIEIDPKELDYLDISPKQIVSISTALIPFLEHDDANRALMGSNMQRQAVPLVFPDSPIVGTGIEHRIAKDSGSCVVSRRAGTVTYVDADLIVIRTDDGGQDEYHMPKFRRSNQGTVIHQRPLVYTGQHVDANEIIGDGQACDQGELALGRNVVVAFVSWEGYNFEDAILLSQKLVKEDFYTSIHIEEYEVESRDTKLGPEEISRDIPNVGEDALKNLDEDGIVRVGAEVKAGDILVGKVTPKGESDQSPEEKLLRAIFGEKAREVRDTSLRVPHGEGGKVVEIKRLSREKNSEDLSPGVNEVVKVYVAQFRKITEGDKMAGRHGNKGVVSRIMAEEDMPYLSDGTPVDVVLNPLGVPSRMNLGQVLETMLGFVAMQRGYKVVTPVFESATAEDIADDVKWVQENRYPEMRDDCKITIYDGRTGEPMANQVMVGVMYMLKLIHLVDDKIHARSIGPYSLITQQPLGGKTQFGGQRFGEMEVWALEGYGAAHMLQEMLTVKSDDIRGRLKTYERIVKGENLAKPGVPESFRVLIKELQGLALDVEIMYADGSFGELVLNDDEDERSPRHVSFKPDATVDDLDAVFNQDMTVPAKASGVSDLFHEGSVEYSGLELHETDEERDAAILSDDLFESEPQTGEQGDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA33</accession>
    <name>A0A011AA33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrA</name>
        <name evidence="10" type="ORF">Cloev_1021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711048.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1091"/>
    <dbReference type="HOGENOM" id="CLU_002977_6_1_0"/>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="9">
        <location>
            <begin position="19"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="817" mass="91087" checksum="1B15F35E8DA4E043" modified="2014-06-11" version="1">MDHNSKQSNLFEINKVIPLPLEEEIKQSYLNYAMSVIVGRALPDARDGLKPVQRRILFAMMELGVRHNQAFKKSARIVGETMGKYHPHGDAAIYDTMARLSQDFSMRYQLVEGQGNFGSIDGDPPAAMRYTEARLHALGEEMLTDINEETVDWGPNFDESLEEPLVLPSRVPNLLVNGSTGIAVGMATNMPPHNLGEAVDVCCAILDNPEVELGELMGLMPGPDFPTGGIILGREGIIDAYRTGRGKLVVRGRVDIEDGRKGKRSIIITEIPYMVNKTNFIETIAKGVQSGLIDGISDLRDESDRNGMRIVVELQRDADPNLVLRQLYTRTQLQSTFGVINLAIVNGETRELPLKELVQIFLDHRREVVRRRTEFRLRKAEDRRHIVEGLLRALDVIDQVIHIIRSSDTAATARNNLIEELGFTEIQAQAILDMRLQRLTGLEREKLDTELAQLLMDIERYDSILSSQLILDSVVKDELMEIRRNYSDKRRTDIENAVGEVADEDLIPEEDIVVALSRDGYIRRMPLQDYRVQQRGGKGVKGVATKAEDEIAIIATTTTHRTLYLFTNKGRVFGVRGFSLPEPKTGKGKLVGTIITLEKEEKVVAIKDSLLGGTKFIFFVTKQGTAKRLPVEELDGLTRAGRRVLGISEGDDISRVRFTSGTDDLLLTTALGQTLRVNEEEFRPLGRQAQGVRGIRLDDGDSVVGCDVVSDGRHVLFISERGIGKRTSYDEFTQHHRAGYGVRAMKLSEKTGDLVGAWGVQDDEEIIVISSKGRMVRIGAQEISTLSRTATGYMIVTLDEGDTVADISIVRKDDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA46</accession>
    <name>A0A011AA46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAS domain S-box</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_1037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484902.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1109"/>
    <dbReference type="HOGENOM" id="CLU_000445_114_21_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="520"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="729"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="1076"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="1322"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="768"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="1374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1453" mass="162752" checksum="6EE30C0DF2D513E9" modified="2014-06-11" version="1">MDGQKTISPLALLERFCVNDFCRRDAEGSLACLSKDVYWCGTSSNEDIHNICEARAYLEREIASRPAPYEMAFSGEDEETTPEGAGCASAKLTLTGEGRSAAGRVSIACIPEDGTARIRCLHMSMIDSFEKEAAAPSWGYAGEDGPKPLYDFVNSSLHGGMLGGYLDEPDMPFYFINEQLLNYLGYERREEFLAATGGKIANRVHPDERAAVMGSLFAQMESSDEYLLAPYRMLKKDGGFIWVTENGKRITAGDGRPAAVCLCIDVSAVVEAQERLRHGKKEMENILNSIPGGVAIYKVSDRFDTVYFSDGVPSLSGHTVEEYHELIKRDAAEMVYAADTERVVSAIREGLAKDTPIDITFRKRHTNGALIWVHLQGKKIGESDGFPLMHAVFHNISRETELYRDILNENNTIIQVSDLETREVLYANRAAAEFSGNPEGDFSGRLCYEFMMHRDSPCSFCHVPQLTKDNFLEAEQYLASKDRWYSVKGKLIEWNGRSAAVEYVSDITDSKRLHQRLETEKSSLENIINSIPSGICVYRLNGGVVELAAANSTIGDMLGVTREGLKDNISADIFRNIHPDDAALLKEKMAEARGGARRMECAYRLRSNATGEYRWVYHSANFIPEPDGSQTAYVCYTDISAQKAAEDKLKRQAEYLQRLYDTMPCGISQYSVNDLGGAKPYHYVNRRGREIYGVSEANEDRLAYARVHPDDRDEYTKMLKNVIANGEASSYELRFIRRDGGIFWISGIIERITDIAGNDIYQSVYNDITELKEAQLRAEEEYQLLSRRYDEELNNLKDVSGDHVSIMRINITKDVVEDLVDIHDGSIPFHCGMSAAEIVENMGPFFVSEESKAAFLDKIDYGNLIREFELGNNRLTFEQPFIDREGNLLWMELQITVRKHPDSGDLIAFFCERDITTRKQLADTFKMVVAQDYDAVIRLDGKHNRYELFVSEPSEGEPPACVANDYRRDIALYAERFIVPEDRERALREMEYADIVPRLERQDVYQVLFDTRDASGARCRKSIKYSYIDRQNQILLMTRQDITDAVAAEKRAKDEIAAALKRAELASLAKGEFLARMSHEMRTPMNAIMGMTALLQDVLGDREAEEDYIGKINSSSRFMLALINDVLDMAKIESGEFLLYPSRYEYKEFAGAIEAMIEPLCRRKGVEFVFDGNWPAAAVWVDKVRINQIFLNLLSNAVKFTPAGGRVEYRMPRADIRGGRVCCDYIIRDNGIGMSKEFQTRLFEPFMQENAAAGIGSRGTGLGLAIAKSIVDKMGGSLDIWSEEGKGTEIRLHLELDIAKDAPEAAAGGERADCAGALNGRRVLIVEDHPLNTEIARKLLEKKGMLVTAAANGAAAVETFVNSQEGCFDAVLMDICMPEMDGLTATKKIRKLPRADAESVPIIAMTANAFDDDRRKSEAAGMNDHLAKPIEPELLYSTLAKAISLYEKSRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAE0</accession>
    <name>A0A011AAE0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709813.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1215"/>
    <dbReference type="HOGENOM" id="CLU_155837_2_0_0"/>
    <dbReference type="OrthoDB" id="2047723at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="82" mass="9343" checksum="BF08F5AA692286FF" modified="2014-06-11" version="1">MLNTNITNFRKNIFMLLEQTIKYNEPVNISTKDGNAVILSEEDYNGLMETLYLSSIPGMKEKIVEGLNTPLEDCIAEDKVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AAE5</accession>
    <name>A0A011AAE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-nitrite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442462.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1220"/>
    <dbReference type="HOGENOM" id="CLU_003291_4_4_0"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="407" mass="44456" checksum="6CB38E0C0055D695" modified="2014-06-11" version="1">MRHLIIGASAAGIAAAKKIREMRANDGITVIAKDAKVHSRCMLHHFLGGRKSAEEINFAGADFFERNNIRFIAEEEITAVCPRENCVIGARSGKLPYDVLLITTGARFFIPPIPGFREAKNVYGLRDLSDAQKIDAAALGAKECVIVGSGLVGLDAAYALCERGIKCRVVEMEDRICPLQLDAVAGAPYQRLFEEAGCEFFLAKRAAGSELDDAGDMRAVLLESGERLPADFVIVTAGVRPNIEFLEGSGVVTDRCVKVDDGMRTNIENIWAAGDVAGLSGIWPNAALQGETAARGMCGESVKYSDRYAMKNTMNFFGLTTLSLGPNSAEAGDETVVNEWRSGYTKAIIRDGRLVHLTIQGDISNTGFWQELIKRGLKVKDAKKPLERLSYADFWNYDEEGGEYLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCG9</accession>
    <name>A0A010YCG9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mscL</name>
        <name evidence="11" type="ORF">Cloev_0024</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441209.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.29"/>
    <dbReference type="HOGENOM" id="CLU_095787_2_3_0"/>
    <dbReference type="OrthoDB" id="1863650at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG77930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="146" mass="15806" checksum="4E977DE25B3CEC7E" modified="2014-06-11" version="1">MKGMLNDFKEFAMRGNVMDMAVGVIIGAAFGKIVTSLVNDVLMPPIGLLVGGIDFSNLFISLSGTHAATLAEAQAQNIPVIAYGVFINTVINFLIQAWAIFMVIKFANKLKAEKPAEPAQPPRLCPYCFSEVNEKATRCPHCTSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCT3</accession>
    <name>A0A010YCT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058050_0_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="290" mass="30626" checksum="6ED134D20A73874C" modified="2014-06-11" version="1">MKKVEKHLFPKDIKEALAFLEEYKGEARLVSGATDLMLWIRDGKVSPSVLVDVSDIPEMKFVSVMNGKMTIGAAMTHAEIAANESVKQIFPALSDGCRSVGSPQIRNIATLAGNIVSAQPAADSVVPMTALGAICEIANCEGARMKPLCELSKRVGESYVDPTKEILTKIEIAIPAGKYGTAFKRIAPREAMALPVVNVAVMLEAAEDGAISAARVVASPVAVVPFRAQRAEAHMVGKKPSAELFAEAAAIAEEEASPRDSLVRGSGAYRKALVKDLVEQALTEAAAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCW3</accession>
    <name>A0A010YCW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cloev_0180</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709286.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.197"/>
    <dbReference type="HOGENOM" id="CLU_023810_1_2_0"/>
    <dbReference type="OrthoDB" id="647136at2"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="320"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="156"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="443" mass="48800" checksum="507BA6F1ACF4A1F9" modified="2014-06-11" version="1">MKICVVGTGYVGLVTGTCFAENGHTVCCVDIDEERIGKLRNGISPIYEPGLDELIERNQREGRLSFSTKIKDGLEGTQLCFIAVGTPPADDGRADLAQVLAAIDDIGSELSHSCYIVVKSTVPVGTGTLLCKRIKSHLRGRGMEKINLEILSNPEFLKEGMAIEDCLHPDRVVIGAASDEARAVMRELYLPFVSEERIIFMDPASAEITKYAANTMLAARISFMNEIAQLCDKVGADVLSVKKGMASDRRIGEYFLNAGCGYGGSCFPKDVKALCYIGEGQGLDMTMASAVSKVNRKQKEQLHIMMRERFGEDMEDIEAAIMGLAFKPQTNDMREAPSIALIRGLLNCGAAVRAYDPIAMDEARKLLPENVGYAGDIESLVDGADCAVIVTEWRQFREADWEKLGKLMKRKIVFDGRNICDPDKMRALGFEYYCIGRNMRPCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCW9</accession>
    <name>A0A010YCW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709292.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.202"/>
    <dbReference type="HOGENOM" id="CLU_033536_0_0_0"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="11"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="320" mass="36690" checksum="28D9D56F1C495EEC" modified="2014-06-11" version="1">MLEAAKAVEVSIVIPAYNEEESLHKLFEELWPVMENLGRSFEVIFINDGSRDATMGILYDFYRLHPEMRVIDLGANFGQHMAIMAGFDHARGGKIITLDADLQNPPSEIPNIIKQMDEGHDVVGTYRVGRRDPIFRKVASKFINKLTNRIAKLKIRDYGCMLRGYDRRIIDIINHSQESTTFIPALAQKFAVNPIEIPVAHRERELGESKYGLFQLIRLNFDLMTSFSLVPLQLVTMAGMLLSVISFLLLFYMFARRLFLGVGTWQLFLEQAFEASQFVIGSITLFSLGIIGEYIGRIYREVSKRPRYSVRKIFEHDDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD14</accession>
    <name>A0A010YD14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0221</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484791.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.240"/>
    <dbReference type="HOGENOM" id="CLU_038053_1_2_0"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="529" mass="59801" checksum="70E808AE6B37D7AE" modified="2014-06-11" version="1">MNKIGKWIVWALIAAFLLGFLPTIIDTLAGFFVLTEEGLGVTQHFTRTLDTVVATAESYMWHIVIAYSIIIAFIIFMEGQNPDRTILWMLVLVFVPVFGVILYLILGPDLQSIRNRRLFRPAKKYGFDHSPFKKATEDQFLIGSMLHACSGADLLVRNRVEILINGAETFPAIEAAIAGAEKFIHMEFFIIRDDDLGRRIGGMLMEAARRGVKVRVLYDAVGSWSLKARFVKELEEGGVECRSFMPVSLPLFRRKMNFRNHRKILVADGKVAFTGGINIGEEYDGKGHLGFWRDTFVRLEGEAVAALHNIFLHDWCVRSADDPAAICEDLNITLNGLPVKDDYSALPVIPLQVVESGVDSVWHSIAKGYYGMISRAQKRVWVTSPYLVPGPELMNALIASSLSGVDVRVMMPSVKDHFLVFWGSRSNIEPLLRAGVRVFQYQDGFIHTKSVVSDSCIASVGTCNMDVRSLDINFENQLFIYDREIAESFARQFETDMKRCKELHIGEWEKRPLWQKLLESFGRLYSAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDN8</accession>
    <name>A0A010YDN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methylmalonyl-CoA mutase, N-terminal domain/subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0402</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484823.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.444"/>
    <dbReference type="HOGENOM" id="CLU_009523_6_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016866">
        <property type="term" value="F:intramolecular transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="5">
        <location>
            <begin position="48"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="738" mass="80936" checksum="22FBD5E0C5EA6681" modified="2014-06-11" version="1">MNETEVKMSEFPPVSFEEFAVPTREQWYDEAVAALKGAPFDKRMFTPTYEGITLEPVYTLADNEELLNIGGMPGEPPFLRGTKSSGYIAEPWKIAQSSSDVLPEEANEAVKNELRKGATILNFELDDCTKLGRDPDPALFKDDYRGLSLTTLRDADEMLKDLDFTKVPLHIYAGASAVPVLALVAAQARAAGVKESLKEAKGCVGADPLGELAERGNLPLPIDEFYDEMALAIKWAEENAPKLKTILVRGDVYHNGGASATQETAYAMSAAIAYIRAMRHRGLEPETVMPHIKFSFSIGTNFFMEIARIRAARTVWAQIAEAFGVDADGRGKIDIFARTSHFTSTVYDPYVNILRATTQAFSGAVGGVDSMQVSCFDDAIRPSGEIAKRIARNIQIMLQTEFDMLQPVDPAGGSWYVERLTTQCAAAVWALLQDVDGEGGMYSALKKGAVQGEIEKVFKNRLKNLAFRRDRAVGTNMYPNTLEKPLKNMFPGGEKLYRARKASVDKFLELTDRQHAAECLDKIMENVHEGDAKFVDAVIEAFLAGATVGEVRNALNDGFEGEESVKAVGTHRWTEQIEALRKTTEEFAERTGKNIRVFLANMGPIPQHKARADFSAGFMEVAHFEVLRNNGFPTPEEAVRAAVESGAEVAVICSADDTYPELVPPVARGIKAAAPEMRVLLAGAPAAEYKDTYVEAGVDDFIHVKANCYEILKTIQEKAINASGCRTAEKNPRKGEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDQ3</accession>
    <name>A0A010YDQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAP-type C4-dicarboxylate transport system, small permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0422</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709125.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086356_3_6_0"/>
    <dbReference type="OrthoDB" id="1947990at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="172" mass="18989" checksum="2C477BF57F4BDB04" modified="2014-06-11" version="1">MPSKKLNKILNSLQTIEDGILVIAFGVMVVSFFLQVVNRNIFKLSMSWFEELATFCMIYMAFLAAEAGLRDGTQISVTALTDKLTGKPKIFVQLVAKAIVITFSAIIFYTSIDMLRMQLISQQASPALGIPMVIPYFAITLSFAIITVIQSAVFAVMLKEFFNKGPNSEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDR7</accession>
    <name>A0A010YDR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441661.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2664603_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="75" mass="8848" checksum="C802DDCA1BD745C6" modified="2014-06-11" version="1">MSKFIEYKTEYYDKEQAAAAFPEIQSPKPGYYVSHPRKKVMGPYENRERAIRYISSEIYHDVELEKLAEEQKKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDS1</accession>
    <name>A0A010YDS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441674.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1944996_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="129" mass="13934" checksum="38A4969BE07FD478" modified="2014-06-11" version="1">MENKSSRVIFFDEQGEPVPMEFEGASARFLNVVRDCFCDPENKDLKAIAFNASFIHDGEQELFSGGMWGDGETLVRLIANLVVGYAVNVSGQPMGVSVADINGYALKLVHGIEREAAKSKGGIILPKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDV5</accession>
    <name>A0A010YDV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441751.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_899269_0_0_0"/>
    <dbReference type="OrthoDB" id="2036573at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="309" mass="33001" checksum="B9603CF70C5E8028" modified="2014-06-11" version="1">MQGPFYNRYNSALSPEERQGLYERLMDMSMSEGRNRYNDMNDYDMAGAYLAGAMEPGGNGHFTDEWKKPNHPTFSQESRYNGVDGYSGGVWAEDGSGETTFTPSAWNLENMPPEEMQRYFGIAEPDARLVLPGNGGGNKDMAVQYVQNGGGGGPWGLVGSLLSLAVPGAAPWIAGAKAVGSAVKGDYGGAVKQAAGLLAPNIGGGSNGKIPSLSGSSPADLTGMLKQNLSNANPTALPDFSKIPDNLSDMGTRYVGNRMQSPGFVSNLIGGGGNGYRLSDADKRRYDELLVQYGLSDMDYSTRQRRNMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE11</accession>
    <name>A0A010YE11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative HD superfamily hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709674.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.600"/>
    <dbReference type="HOGENOM" id="CLU_090635_1_1_0"/>
    <dbReference type="OrthoDB" id="1433958at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="195" mass="21849" checksum="25B31D4AE4F9FC33" modified="2014-06-11" version="1">MSDGVTREAAAGLLKKYNKEEFHLLHALTVEGVMRWYANDLGFADEADYWATIGLLHDVDFECFPDEHCKKAPELLREIGADEAMIKSICSHGYGLCTDIKPEHLMEKTLFAADELTGLIWAAALMRPSKSVSDMELKSLKKKYKDKKFAAGCSREVIAQGAEMLGWELDTLLEKTLEAMRSCEAEVTANLEKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE14</accession>
    <name>A0A010YE14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709694.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.606"/>
    <dbReference type="HOGENOM" id="CLU_133782_0_0_0"/>
    <dbReference type="OrthoDB" id="1929935at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007437">
        <property type="entry name" value="DUF486"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38482">
        <property type="entry name" value="PTHR38482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04342">
        <property type="entry name" value="DMT_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021239">
        <property type="entry name" value="UCP021239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="114" mass="13100" checksum="0707EE139C2D58E9" modified="2014-06-11" version="1">MLRYTAPLILLFVSNIFMTYAWYGHLKYVGAKPLIVAILVSWGVAFFEYCFQVPANRIGHAVYSLPQLKIMQEVITMAIFAGFSFFVMKEKLSLNYLWASFCMVGAVFFIFRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE72</accession>
    <name>A0A010YE72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable transaldolase</fullName>
            <ecNumber evidence="9">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tal</name>
        <name evidence="10" type="ORF">Cloev_0636</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the transaldolase family. Type 3B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441881.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.682"/>
    <dbReference type="HOGENOM" id="CLU_079764_0_0_0"/>
    <dbReference type="OrthoDB" id="784333at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00956">
        <property type="entry name" value="Transaldolase_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00494">
        <property type="entry name" value="Transaldolase_3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022999">
        <property type="entry name" value="Transaldolase_3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004731">
        <property type="entry name" value="Transaldolase_3B/F6P_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033919">
        <property type="entry name" value="TSA/FSA_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00875">
        <property type="entry name" value="fsa_talC_mipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="218" mass="23406" checksum="41FA16BE1585787F" modified="2014-06-11" version="1">MKFFLDTANLEEVKAACSWGVIAGVTTNPTLVSKEGNIDFHTRVREIAETVNGPVSAEAVSLEKDKLIEEAKVIAKIHPQVVVKVPLCPDGLGAVKELSALGIKTNVTLVFSANQAVLAAAAGAAYVSPFVGRLDDIGEDGIKLIYDVVEIFDLYGIETKVIAASLRHPAHVLECAKAGADYATVPFKVLKMLFDHPLTTKGIDQFNADWAKYLSGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE80</accession>
    <name>A0A010YE80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441894.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1493727_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="180" mass="20707" checksum="F6C7EAD277D06DFF" modified="2014-06-11" version="1">MATATAKTAAPTQVMTVVQVKRFNRWWSETTTETRHQMPTELKEYMRQAGGYTPSAERMIYSMFSLLDRTCYCASENLDDHPKLQQRVGARQYEFRALKGEEYDKMTVCFNSHIKFMEYAKKVCCDAEDFISGLDCIEGKGYEHYADTFREFSGKFEELIASAYLAASVCLNIAPETEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEC3</accession>
    <name>A0A010YEC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="73"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="257" mass="28712" checksum="8061B744DA6728C1" modified="2014-06-11" version="1">MFGTVKGMEMSAIDKAVTLLEILAASKEEMSIRELEKQSNISKSTIHRVLQNLQQRSWVAQNTETERYNIGLRFLFLYNTDSFYRHFLDVARPLMDRLVSATGQTALISVLDKLEGHCIFTKTPPTLLQYAAYPGMRFPIYAGATGKILLAFAPDDIREKVINDNKVQVAPNTIIDEQRLREEVAKIRRDGYAFSTKELQNQTSGVSVPILTANGELIAQFGIAGPAADFENKFESMLEEVQKAAKAFSDALNARTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEG7</accession>
    <name>A0A010YEG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative TIM-barrel fold metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710619.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.783"/>
    <dbReference type="HOGENOM" id="CLU_009942_1_0_0"/>
    <dbReference type="OrthoDB" id="751534at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="55"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="541" mass="59676" checksum="14CBF7750C393AE2" modified="2014-06-11" version="1">MAESIRTDSIALINSVIYPMAYPGRAQAIFARGGVIETLGTDKEILAKCDTRTVVLDMKGRYILPGFTDTHNHLLAAGRSIETLDLGDARSIDEMIGKGRHFLAENDISPDGWFFARGWDQNHMAENRFPNRFDLDLISTDIPLFFERSCGHIAALNSRALEILKIGPGFRISGGVINTDEKGEPNGVVSEAAVNWVRMNIPEHSTETLRHWYGLATEKMIRCGITSVQTDDLEMVGRAQGVFDLYESMEADEKMPLRVAQQWHLRDEEELAAFIENGNNKRSGRYFHSGPLKIHVDGTLGARTAALREEYSDDPGNRGVYAHSQGELNRLVQRAQEAGMQVAFYAIGDGAIERCLNAVETAKSAANNGIAHRIVHCQVGGADLYSRMASLGVMADIQPAFVTSDWPIVISRLDTERARWSYAWKSLINSGIPVGAGSDAPTEPLNPFVGIRAAILRQDLNNEPEHGWMPSQCLDRVEAFSMYTSGGAKICGELSWRGTLEPGKAADMVAFMEDPFIVSENELLDITTGLTVVDGKIRYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEH8</accession>
    <name>A0A010YEH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroorotase-like cyclic amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441992.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.793"/>
    <dbReference type="HOGENOM" id="CLU_015572_4_2_0"/>
    <dbReference type="OrthoDB" id="906155at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="52"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="463" mass="51012" checksum="2641E29578C0D76E" modified="2014-06-11" version="1">MIYDLVIKNAKVYLNGTFQPCDVAVSGETISCVAPWGSEWQAAREIEAGGQYLIPGTIDTHVHFRDPGHPERETFYTGSMAAAAGGVTTVLEHPISNPPQHNKAILDHRIEVAKPQACVDFAFYGAAGGRSLEDIVPLSHEGIVAYKTFLHEAPEGRAAEFEGLTMGDDAQLYYGMLEVAKTGLMLATHAENNDLVTEMTRRMRASGRSDPMSHNESRPPIVEIQTVEKLIRFVRETGVKLELAHISTDGAMELAKRAKYEGLPVFLETCPHYLFLDENAIVEYGSFAKFQPALRKRETVDKLWDYINDGTVDYIGSDHGPFTLAEKLRGGGNIHDAFAGTPGIDLRLPLMLDAAYKGKVSLERCVELLSVNPAKCFDLYPQKGSVSPGADADFVLFDLDGTTTVRWENSYCKSKDAGHVYEGWDLHCRLHKTIVRGRVVMDEGAVDPSARGWGALVKPLTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEJ7</accession>
    <name>A0A010YEJ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRISPR-associated exonuclease Cas4</fullName>
            <ecNumber evidence="6">3.1.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0758</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+) or Mn(2+) required for ssDNA cleavage activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CRISPR-associated exonuclease Cas4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.12.1" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133784_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013343">
        <property type="entry name" value="CRISPR-assoc_prot_Cas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00372">
        <property type="entry name" value="cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="7">
        <location>
            <begin position="10"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="168" mass="19378" checksum="E0FD1BB8749BE9D4" modified="2014-06-11" version="1">MFSEKARITGMILQAYGICHRQVWFLTHSVFADQENELLSLGRIVDENSYAREKHQVMFGGNKFDFMRNQDGLLVISEIKKSSRAEKSSILQLAHYLYELEKEGIASMGVLLYPTEKKRTAVILTEELKRVLDQSYAVIEELALSEKPPHLVQCKYCKKCAYGDYCWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF03</accession>
    <name>A0A010YF03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484885.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.957"/>
    <dbReference type="HOGENOM" id="CLU_046640_1_1_0"/>
    <dbReference type="OrthoDB" id="466535at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009362">
        <property type="entry name" value="YhcG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041527">
        <property type="entry name" value="YhcG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17761">
        <property type="entry name" value="DUF1016_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06250">
        <property type="entry name" value="YhcG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1016_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="YhcG_C" evidence="1">
        <location>
            <begin position="171"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="338" mass="39171" checksum="04FB221B7EEB0EE4" modified="2014-06-11" version="1">MSSQLIHNNHAAYGEIISIIERSRENAFRAVNRELISMYWEIGAYVSNKVKNGGWGKSIVTDFARFMESERPDIKGFSASNIWRMRQFYETYSGSEKLAPLAREISWTQNLIIMSRAKTDEAREFYLLLCGRNNYTKRELERQIDSMLFERTLFSDERNKLFLAKNTGLTALRDSYVLEFLNVPENHKEKELRKSIVANIRDFILEFGKDFTFVGEEYLVQVGNKDFHIDLLFYNRELSCLVAIELKVTDFKPEHLGQLEFYLEALDRDVKKPSENPSVGLILCAGKDDMVVEYALSRSLSPTLVADYQLHLPNKNILTEKLRELKELADVETGEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF05</accession>
    <name>A0A010YF05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">S-adenosylmethionine decarboxylase proenzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0899</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.962"/>
    <dbReference type="HOGENOM" id="CLU_092007_0_0_0"/>
    <dbReference type="OrthoDB" id="757383at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00465">
        <property type="entry name" value="AdoMetDC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009165">
        <property type="entry name" value="S-AdoMet_deCO2ase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001356">
        <property type="entry name" value="SAM_decarboxylas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03331">
        <property type="entry name" value="SAM_DCase_Eco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="270" mass="31439" checksum="68FAA6685E52543C" modified="2014-06-11" version="1">MKDKIQLYGFNNLTKTLSFNIYDICFAKTDREKQDYIAYIDEQYNSERLTKILCGVTDIIGACVLNISKQDYDPQGASVTILISEESVPPAQIDESCNMGRWAEKINEERETVVAHLDKSHVTVHTYPEFHPNNDISSFRVDIDVSTCGKISPLNALNYLIGQFDSDIIALDYRIRGFTRDIDGKKYYKDHEINSIQNYIDEATLRRYDAIDVNVYQSNIFHTKMMLKEIRLADYLFNIDPRELPPEERLSITDRITKEMLEIYYGMNMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF17</accession>
    <name>A0A010YF17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442161.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_3_1_0"/>
    <dbReference type="OrthoDB" id="1650683at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="259" mass="29612" checksum="2B4CE3F1AFD4AFD6" modified="2014-06-11" version="1">MKISSIQLEIKNSRSKKETINYVLELMDKCAGDDLIVLPELWNIGFFSYDEYKATSESLEGETATTISHKAKELRAYVYSGSFVEARNGKYYNTSILFDREGRNVLEYRKMHLFSYKCREPEILTPGEEMSVVSTEFGRVGLATCYDLRFPELFRKMVIEQGAEFFLVTSAWPFPRVEAWNALNQVRALENTCYLISCNAAGVDHGIRLAGHSQIVDPWGYVIASSGYEETIVRAEISSGSVYRIRKEFPVLEDRRLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF20</accession>
    <name>A0A010YF20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TRAP transporter, DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0920</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442173.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.986"/>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_0"/>
    <dbReference type="OrthoDB" id="903568at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="354"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="435" mass="46236" checksum="B23C518BC266E572" modified="2014-06-11" version="1">MLACLITILLAAMALGVPIFISMSLSTITAMLAFGNYDIVIAMQRLFDGMDKFSLMSMPFYILAADIMIVGGLSKRILDFADVFIGGFHGSLALTTEASSMFFGALSGSSPATVSAIGTMMYPQLVKSGYGPKFSTGLITSAGSVAILIPPSITFIVYGAVTGVSIGALFMAGFGAGLVYGAGVLLYSYWYARKNNIPLSKSATWDEKWKATKDASWALGVPIIIMGGIMSGMFTPTEAAGVSVVYAAFVTSVIYKELTFKGLIKALLRSSVTISQLMILLGAAALFGWAFTVTYVPQMFMAHLVEVVNSPYVFLLILNIVFLILGMFIDGSAAITIMAPLFYRPALSMGIDPVHLGAVAVSNFAIGMFTPPFGLNLFVSKTISDLKMSGIYSAVLPFIIINIITLLLITYIPDISLLIPKLTGYVGSQSVLGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF29</accession>
    <name>A0A010YF29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hydro-lyase, Fe-S type, tartrate/fumarate subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0945</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442219.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1014"/>
    <dbReference type="HOGENOM" id="CLU_041245_0_0_0"/>
    <dbReference type="OrthoDB" id="972093at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="291" mass="31435" checksum="5430E8450472E4C1" modified="2014-06-11" version="1">MSKIYRIMAEEVAEKVCELALTANMYLPEDVKRALAEARSAEKMPLARSTYDEIIKNAELAAEKYMPICQDCGMAVLFAELGQDLHVEGGGLEEAINEGVRRAYRKGYLRKSVVSDPLVDRRNSGDNTPAVIHWRVVPGRSLDITITPKGMGSENMSRIFMLKPADGADGVIKSVVETVEQAGSNPCPPVVIGVGIGGNFETAPLAAKEALLVPYGERHPVSAYAQMEERILREVNRLGIGPAGIGGTVTALDAHIVTRPTHIAGMPVAVNLCCHALRHARGRIDGRAENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF99</accession>
    <name>A0A010YF99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="10" type="ORF">Cloev_1041</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711084.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1113"/>
    <dbReference type="HOGENOM" id="CLU_024321_0_0_0"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="9"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="425" mass="45134" checksum="5247BA2F52032D8F" modified="2014-06-11" version="1">MKKGITITPKPLAGTIKIMPSKSMSHRMAICAALAGGSQVRSLGLSEDITATCRVLRGLGCEMELTGDTLTTGPKKEPPREAEPLDCGESGSTLRFIIPLALDGKRRRFTGQGRLMSRPQAEYERIFTERGIDFIRSDDYIEVCGRLRPGVFEVRGDVSSQFTSGLLFALPALDGDSRIVVTTPPESRGYIELTLSALAGFGIKAAWDDGGRALNVPGRQRFAPAAVTVEGDFSHAAFWLAAGAVGGGAELTGLKKDSLQGDAMIVELARRMGAAVEWRGEKLCVARSKLRGAEIDVSQTPDLFPALSVLAACAEGETRLTGAARLRIKESDRLAAMAAELAALGAEVREGEDSLTITGGGKLRGGAVSAHNDHRVAMSLAVAASACVGETTIDDAECVKKSAPDFWKEYRAMGGSFMIDKEGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFA2</accession>
    <name>A0A010YFA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442351.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128110_0_2_0"/>
    <dbReference type="OrthoDB" id="1680806at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008878">
        <property type="entry name" value="Transposase_IS66_Orf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36455">
        <property type="entry name" value="PTHR36455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05717">
        <property type="entry name" value="TnpB_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="128" mass="14379" checksum="C68DC10F882B6C03" modified="2014-06-11" version="1">MLECSGKEIYLVCGATDMRKGLDGLAAIANLRFACVSFGSAMFIFCNKNRNRVKIIEWDGDGFWLYQKRLERGTFPWPPDGHGKRISVTGEEFSCLFAGTKLRRKLSMSEVFPAASVQDNSRNCKSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFH9</accession>
    <name>A0A010YFH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fe-S-cluster-containing hydrogenase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1146</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709801.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1219"/>
    <dbReference type="HOGENOM" id="CLU_043374_3_1_0"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="150" mass="16779" checksum="ABC1E7E36A483743" modified="2014-06-11" version="1">MKRIFIDADKCDGCMNCSLACMNAHRKDGADNIYSLDLNDPENESRNFILQDGEKHYRPLFCRHCGEPMCVTSCMSGAMRKNPETGLVEYDETKCGACYMCVMNCPYGVPKPDAATRTFVIKCDFCAGKEEGPSCVRACPKEAIYLKEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS23</accession>
    <name>A0A010YS23_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cloev_0002</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708498.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038149_4_2_0"/>
    <dbReference type="OrthoDB" id="1040142at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="130"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="249"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG77908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="388" mass="42320" checksum="1693D6302A56AE59" modified="2014-06-11" version="1">MKLTINKKQFLASWGLAERSTSASGSVSILSSILVKAGFESVLLQATDIKTSIICFASGVTVNEPGEAVFPIKMVSDLFKKAPGEEFTVEVNEGRVTLRAGRSKYNFSSYPVREFPALPSSDNAGVFCRLSAADLAKVIDEGTLAASTGEEFPLYLSSANLQISQNRLSIISTDTRRLAISSALAADGVEDAAALLPMKGVKELQRILGSLNPETEVKVLYDSAQFYFKTDTLEFTVRRVESKFPPYEKILPKNSTLNVVTDRGSLISALERVDVIVRDFNRMVVLDIIPGAEIVLLAKAPDFGQAKEEIGAEAEGEKLRIAVNSKFFLEALKVMRDPEVKLSFNGQAGHMAVKRGDSDDFLCLIAPINLSEEELRMFDMEQNGTDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSB8</accession>
    <name>A0A010YSB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacid CoA-transferase, A subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709209.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019942_2_0_0"/>
    <dbReference type="OrthoDB" id="1660857at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="222" mass="23705" checksum="9A7D1896EA918FCA" modified="2014-06-11" version="1">MREITCSKLCSFNEAMELIKDGDRIFISGFGNAGDPKQLIKALVETDKKELTIISNDLGSPNIGLGQLLTKKKIKGLIGTYYNWNTEVADAYNAGEITVELVPQGSFAEGIRAAGVGSAGFYTKTAVGTELAKGKDTKEFNGETYLLQEAITGDVALICADKADELGNLVYHKTARNFNPVMAMAAKTVIAEVGEIVPAGALDPESIVTPHIFVDAIVLRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSG7</accession>
    <name>A0A010YSG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709289.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.200"/>
    <dbReference type="HOGENOM" id="CLU_007383_7_0_0"/>
    <dbReference type="OrthoDB" id="937478at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="340" mass="39091" checksum="1C2FE5B5B0570ABA" modified="2014-06-11" version="1">MKLFITGVNGFIGTHLLENILAKTDWEVDGFDIASTNLEPYEGENRFAFRKGDIFKDNEVLEAEVIKADAVIPLAGIAKPAYYIKKPVWTFELDFEQNLKMVRLCAKHGKRIIFPSTSEVYGMSGDAELKEDESPLTTGPIVKMRWIYSCSKQMMDRMIMAYGQEQDLQYTLFRPFNWVGPRLDTFKDAEERQARSVTQMLYDIIYRRKISLVNGGEQRRSFTWIGDGIEGLTAIIRNEGNKADSEIFNIGNPANNYSVKELAELLIDEAKKFPKFREAAEATELEIIPASAYYGKSYDDMQNRLPSVKKMEMKLGWKPKTGMREMLNKTIEWYAENEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSW9</accession>
    <name>A0A010YSW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441521.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.368"/>
    <dbReference type="HOGENOM" id="CLU_028458_3_1_0"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="89"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="301" mass="33085" checksum="F925D2B6545014D8" modified="2014-06-11" version="1">MRLATFRKWNTERAGLVTKSGILPLTALGARAGFEPEGEIFALIEKEQLEPLTEWYNKGGRIEAEALAEKEAIPYGDVIYGPLYRNPRRIFGIGLNYKDHAGDLGEKTPQVFPGSFYKPASCIAGHGDEIKIPALPEAQKTTAEAELGIIMGKRCKSIEEKDWLKYVAGYTTILDMTEESILRLNPRYLTIVKGFDTFLTFGPQLVTPDEIPDVSALEVATIHNGAVHAKNTVSNMTFCPSKLVALVSHMQGWLPGDILSTGTPRAVHIQDGDTAECRITGPDGFSFEPLVNPVIDLKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSZ1</accession>
    <name>A0A010YSZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lauroyl/myristoyl acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0353</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049421_4_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="243" mass="27493" checksum="7FA5E1086D34D4FD" modified="2014-06-11" version="1">MLAGIAGPRRDIARRNLEFIFPSKPKFKREQILKESYKNLLWSFFEYAAWQKDPAYVNRVAAEVRGFELLEEAISNGRRVIAVSACLGNWPLIAAWMEGQMRFSCLFGRHDEISALNDESLSDQLASEFQKSDVICVAGDRHGGSSGSQLPFLGQMTNTGTLAARCALLSGAAVLVVTCTRISPYRCRINIGFPPEDGAQGDMTEVDFLTLQINRELERRILQFPEQWLWQQKRFIGEVDERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT51</accession>
    <name>A0A010YT51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441654.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.483"/>
    <dbReference type="HOGENOM" id="CLU_796293_0_0_0"/>
    <dbReference type="OrthoDB" id="1742635at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="359" mass="40524" checksum="242FF6149C8EC92D" modified="2014-06-11" version="1">MRELPKRQYNIVSGMLDLWEESGELDAETAEKLRENIAPMPFDWQRAARYLLAAALCCIFVGAAALTRSRWALELMLWLFGGRAIVRCVFFAVVAAALYIWAGKRRVKFPEKAFTNEAVLFLGVLSTAASIAWLGKTLDNGGGHFSLLLGLAALTYGVIALTLDSILIWIFALFSLGSWLGAETGYVSGWGAYWLGLNYPARFSLYGAFLTALSRQMGRYGRFAPFRRGTLSVGLLFLFVSLWIMSIFGNYGDINVWHKVRQAELFHWSVIFAAAAGISLWLGIRRDDAMLRGYGLTFLGINLYTRFFETFWNSMDKGLFFLILGGSLWLLGSKAEKIWDIKKYRELPEEKDERPNDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT80</accession>
    <name>A0A010YT80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1983 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441729.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_614964_0_0_0"/>
    <dbReference type="OrthoDB" id="221295at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015406">
        <property type="entry name" value="DUF1983"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09327">
        <property type="entry name" value="DUF1983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1983" evidence="1">
        <location>
            <begin position="301"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="445" mass="46775" checksum="6828FD8019417780" modified="2014-06-11" version="1">MGNLANTEARIKRLENLLKDETGTGGTGQNGTVLYPVRQLTLTEETSHDDAGNAAVTVLVSWKSPAGSLVPDKIKVMLNGVTAELAGGVTEYRKGGFAAGDTVKVIVTAVYSTGSSSAVTAQLIITGSGAAPDVPSGFSAVGGFCTITLRWGVPAGQNHSHMEIWESTRNDNLETAERIAQAYGTDFVRANCGVMETRWYWIRSVDTGGNKSTFVGPVYAITTPIEAEEIRDGAVTESKLIAGLAQKINDSDAAVQIINQVRTGEVDLFQQPTAPTSGMAAGDLWIDSNEAVYRYIGGAWVKQENTSAYELLKAAIAQYTVKTQVAMDGKLKIAGFGVFNDATTGSEFCVLADRFYIYGQSQDGSYTNVKVFAVDTTKNPPVVGINGSLIVNGTIDGSKINAASKIQLGTLVNGVLTDGQLIIGAGGKIQIGDSIILDGGSGSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTZ2</accession>
    <name>A0A010YTZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ethanolamine ammonia-lyase large subunit</fullName>
            <shortName evidence="1">EAL large subunit</shortName>
            <ecNumber evidence="1">4.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">eutB</name>
        <name evidence="2" type="ORF">Cloev_0766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ethanolamine = acetaldehyde + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15313"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57603"/>
            <dbReference type="EC" id="4.3.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
        <text evidence="1">Binds between the large and small subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine degradation; ethanolamine degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial microcompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EutB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.7" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442021.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.818"/>
    <dbReference type="HOGENOM" id="CLU_048555_0_0_0"/>
    <dbReference type="OrthoDB" id="230269at2"/>
    <dbReference type="UniPathway" id="UPA00560"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008851">
        <property type="term" value="F:ethanolamine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00861">
        <property type="entry name" value="EutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010628">
        <property type="entry name" value="EutB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044939">
        <property type="entry name" value="EutB_dom_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044941">
        <property type="entry name" value="EutB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39329">
        <property type="entry name" value="PTHR39329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06751">
        <property type="entry name" value="EutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018788">
        <property type="entry name" value="EutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="1" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="456" mass="50435" checksum="D922D0E3953200F8" modified="2014-06-11" version="1">MKLKTKLLGHTYEFKSLREVMAKANEEKSGDKLAGIAAENAEERVAAKVVLSEVTLAELRNTPAVPYEQDEVTRIIQDDISERIYDEHKNMTVSEFREWLLDEETTTAMIRRASRGLTSEMVSAVCKLMGNLDLIYAAKKIPVTAHCNTTIGLPGTFSSRLQPNNTTDDPKGIIASVMEGFSLGCGDAVLGLNPVDDSVESVARILKMFDEFKNKWEVPTQICVLAHVTTQTEAVRKFNAPIDLMFQSIAGSQKGNEAFGLTAAMLEEGREMMLRHGTSTGPNVMYFETGQGSELSSDAHNGWDQLTMEARCYGFARHYHPFLVNTVVGFIGPEYLYDSKQVTRAGLEDHFMGKLSGIPMGCDACYTNHMKADQNDIENLAALLVAAGCNYIMGVPQGDDCMLMYQCTGYHEAQTLREIFGLRPIKPFEKWLEKMGFLKDGRLTPLAGDASAFAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU00</accession>
    <name>A0A010YU00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon dioxide concentrating mechanism/carboxysome shell protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.823"/>
    <dbReference type="HOGENOM" id="CLU_064903_5_3_0"/>
    <dbReference type="OrthoDB" id="1802372at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020808">
        <property type="entry name" value="Bact_microcomp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01139">
        <property type="entry name" value="BMC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="2">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="9779" checksum="41D22EF27C14FAA1" modified="2014-06-11" version="1">MMNQQALGMIETKGLVPAIEAADAMVKAANVNLIGKVQVGGGLVTVMVRGDVGAVKAATDAGAAAAERVGELLSVHVIPRPAEDVDYLLPTLKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU26</accession>
    <name>A0A010YU26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484871.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.843"/>
    <dbReference type="HOGENOM" id="CLU_029603_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022324">
        <property type="entry name" value="Bacilysin_exporter_BacE_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01988">
        <property type="entry name" value="EXPORTERBACE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="428" mass="46648" checksum="8B21AFD5999A277B" modified="2014-06-11" version="1">MIETQFSLLAKRRFLPLFLTQFLGAFNDNLFKSALVILITFRLAETYNVNAQIMITAVAGLFILPFFLFSSLAGQIADKYEKSFLIRIIKLVEIILMCLTAAAFETMHLWWLIFLLFCMGTQSTFFGPLKFSILPQLLNDDELVAGNGLVNAGTNIAILTGTLCGGLFILSPLGRHYISAGVVGVAVAGYAASRFIPTAEPSSPGLRIDRNLFRSTWEMLVYPFCNRDVFRSIIGISWFWFLGSVFLAQFPSFAKDALGGDEQVSTLFLVLFSVGVGAGATFCNKLLKGRVSGKYLSCSLIGMSLFIVMLYIFSAAAPAGGELISALQFIRGPRAAGIVFAMFMIAACGGLYSVPMYAMMQRMTPESHMARVIASLNIIDSLGMVAAAMLTALMISAGVSISGIFLSMAFLNLLMLPLTIKLSRISYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU90</accession>
    <name>A0A010YU90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kbl</name>
        <name evidence="3" type="ORF">Cloev_0852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442074.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.908"/>
    <dbReference type="HOGENOM" id="CLU_015846_11_0_0"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="110"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="209"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="240"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="273"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="395" mass="43033" checksum="E094CC49F314B325" modified="2014-06-11" version="1">MKTAIGKIAAEIEKIKADGLYKNERIITTPQRDVIDTTAKGGVVNMCANNYLGLADNARVIEAAKAAYDRWGYGLASVRFICGTQQIHKDLEAAVSRFLGMDDTILYSSCFDANGGVFEPLLSDKDAIISDELNHASIIDGVRLCKAKKFRYKNNDMASLREQLEAAKTAGADIKLIVTDGVFSMDGYIADLKGICDLADEYDALVMVDDSHAVGFMGERGRGTHEYCGVMGRVDIITGTLGKALGGASGGYVSSKAEIVEMLRQRSRPYLFSNTVAPAICGASLEVIKMLEESTGYRDRVHANTKYFREEMAALGFDILPGTHPIVPIMLYDAKAASEFASRLLEKGIYVTGFFYPVVPQGKARVRTQVSAAHTKEDLDRAITAFAEVKREMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUD0</accession>
    <name>A0A010YUD0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rimO</name>
        <name evidence="11" type="ORF">Cloev_0873</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442105.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.937"/>
    <dbReference type="HOGENOM" id="CLU_018697_0_1_0"/>
    <dbReference type="OrthoDB" id="397139at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="127"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="361"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="429" mass="48054" checksum="29DE1C0D823EAAE1" modified="2014-06-11" version="1">MKIYCLTLGCAKNRVDSECLAGALAAAGHELVPSAEDAECALVNTCGFIRPAVEESIAAILDLEELKKDKKLQKIGVVGCLVNRYGEDLPSEVPLVDFWARTEDWKFVLEQLKTPGDDARRRGTLPLSSKYSRYLKISEGCGNCCTYCAIPGIRGPLRSLPVEVIVKEAAQLAEEGARELCVVGQDLTVYGTDTDGRPRLIELLDALESSLPHDLWIRLLYLHPSRVDRALLERVAAGRQVLPYLDIPVQHGDPEILAAMNRGIAPETLRGIFRTAREINPDFALRTTCMVGFPGEKKRHFDNLKNFVSEVRFDRMGAFTFFPEEGTVAAALEEQVPERTKNRRLGELMRLQEEISFGRQRCFIGRELKVLVEKIEREEGYAEGRSFREAPEVDGVIEIRNIREDLKEGDIITLRVAEAMPHDMTGEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUD9</accession>
    <name>A0A010YUD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442118.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066583_0_0_0"/>
    <dbReference type="OrthoDB" id="1820987at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="343" mass="37852" checksum="ACF1BB54874886E2" modified="2014-06-11" version="1">MRISFGKMGDPESKDGMKINYAPAKRKVSKVTWWLILAAVFTPFLWLLVSLGANWLFVSSSGVVAMDSYPVSVVGGGVVTKIYVKPGEFVRAGSRLAEVKRNIPEAEAAERQRVEAELEALGRAGGTAVSNRPSSYQDGMMAHLANEERVMKELMEKGAATRAEYNQAKERRLASQRDIEALKNPPALPDAGVETRKMYLKRYADMLAEKQSTPLTIYAPRAGRVEYISVTPGYDTAGEHELMRIADPGEPYVIAYVLPENYDDRVRPGRVVEVRLPGSGRTIEAVVSEPPLNANSVPGGLSDTILSGRRGIVVFLKPNERLLPEESVNGMPVRVDWGIRFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUE7</accession>
    <name>A0A010YUE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphonoacetaldehyde hydrolase</fullName>
            <ecNumber evidence="1">3.11.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.11.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710882.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.955"/>
    <dbReference type="HOGENOM" id="CLU_045011_12_0_0"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050194">
        <property type="term" value="F:phosphonoacetaldehyde hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01375">
        <property type="entry name" value="PhnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006323">
        <property type="entry name" value="Phosphonoacetald_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01422">
        <property type="entry name" value="phosphonatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="264" mass="29383" checksum="49223A49352A5DB8" modified="2014-06-11" version="1">MNNGKKIKCVILDWAGTTVDFGSMAPLRVFSDIFAQRGLRLETDELRAPMGMPKLEHIRELLRMERPARLFREKYGRMPIDDDALGMYAAFEPALLKILHDFAEPLEGVCGAVRELRETGVKIGSTTGYTRKMMDIIAPLAKAAGYAPDCIVTPDEAVEGRPAPWMIFKNMERLGVYPPSSVVKAGDTAADIREGKNAGVISVGILRGSNELGLTRSEFESLPAKEVDERRQAARERFYLAGADYVLESIRELPAFVREMDKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUI2</accession>
    <name>A0A010YUI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP transporter, 4TM/12TM fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442228.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1018"/>
    <dbReference type="HOGENOM" id="CLU_007041_3_1_0"/>
    <dbReference type="OrthoDB" id="271112at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011853">
        <property type="entry name" value="TRAP_DctM-Dct_fused"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02123">
        <property type="entry name" value="TRAP_fused"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="614"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="2">
        <location>
            <begin position="141"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="661" mass="70745" checksum="9516D78AE5B5C7FF" modified="2014-06-11" version="1">MEEKKHNKSLLEDISMDEAQVSSLVEKYDAESRYRRLTGAQGIFISLWLAAMALFHLYTAGIATMPITIQRAVHLTFAIVAVFILFPASRKSSKMKTPWYDWLLAAAAGGVTGYIVFFFNDIARRGAEPIDYEIYLGIAAILLVLEAGRRVVGNVLPCMSVIFLLYCYFGNYAPGIFQIRGYSLSRIIQHMYLTPEGIFGLALGVSATFVIVFIIFGAYLSQSGGAKFFNELALALAGSKPGGPAKVAVVASGLLGTINGSSVANVATTGTFTIPLMKKVGYPPYYAGAVEACASTGGQLMPPIMGAGAFIMSEFLNIPYLSIAAAAIIPALIYYTAIFTNVHIRARKQKLQGIPKSELPSVGEVMRNDGHLLVPVIVVIVTLLLKYTPLRAGFIGVVSVIIVSSLKKNTRMTLRDNFNALVEGARGGLGVALACALVGFIVGTSSLTSLGLTISNNIIEISGGNLMLTLVMAMVACLVLGMGLPTTANYIVCSTIIAPALIGMKVLPLSAHLFVFYFGIMADLTPPVCLAAFTGAGIAGASPAKTGMTATRIALASYLLPYCFVYNPMLLLHNVEVVELVVLVISAVLGVVALAGSFEGWFYRDLKNYERVVFGVIALLSIHHDFWISIAAIVGIALMIVYFKKSSHDGQLPEKFEEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUJ9</accession>
    <name>A0A010YUJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484898.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1038"/>
    <dbReference type="HOGENOM" id="CLU_069356_12_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="205" mass="23833" checksum="84BF13292F05EAF7" modified="2014-06-11" version="1">MRRTKEQAKETRHAILQAACELFTEGDFSQITLNQIAERAGLTKGAIYWHFKNKNDILLRIIKELCRIDEHEFFEALVMPDSAEDLSTLYKKVLVRPDSDIRYRIGHKLLREDYKWPEEVRAQANDIIGKSLVHEREMVEGFITRAQNSGRIRSDVPPEKVAVMITTLFNGLRTMQIAERLPEEFHGCLNFVFDSFTKELAPVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUS0</accession>
    <name>A0A010YUS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA nucleotidyltransferase/poly(A) polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1062</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442356.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1130"/>
    <dbReference type="HOGENOM" id="CLU_015961_1_1_0"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="241"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="409" mass="45915" checksum="ECE915FF186227B1" modified="2014-06-11" version="1">MTEREFFKKVQEAGGAAYLVGGAVRDRLMGRAVHDRDYVVCGLLPETFRSLFPEARRVGRSFPVFLLEIDGLLCETAFARRERKSGFGYKGFDVFCAPGITIEEDLYRRDTTVNSMAVGADGRLVDPYGGARDIGLRLIRATSWHFCEDPVRALRAARQAAQFGFSIAPPTLAMMERCAEELRSEPKERKFAEFEKALGAERPSIYFRALRAAGLLEGEFPWIYRLIGKGQPPEYHPEGDAFEHTMTALDRAASMTDRAEVRFAALMHDIGKGETPEEMLPHHYGHEERGAAVMREITAVLGLPRLWSRCAEFAAREHMRPSRMKDPAKIRDLIRALEREPLGPDGFGTVVAADGGELPGFLRNYEYLLAIIRTAAKCKVPERLTGPQIGEYIRSKEIEALRTALKDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUT6</accession>
    <name>A0A010YUT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase L1-like esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484907.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1147"/>
    <dbReference type="HOGENOM" id="CLU_051989_9_0_0"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="5"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="198" mass="21409" checksum="7B5769092EE6AA86" modified="2014-06-11" version="1">MKIVCLGCSLTAGYGVSREDSWVGILSRTTCDTWINAGICGDTTGGMLARLGESVFSHSPDSALLMGGINDILASGSWDCARANMMAMVHQCVARGIRPIVGIHIPLYPQTPHPYGSFLNFTLVAEQAQAYAGWLRLFAGGLRLRTIDFGRAYEAYIGESGWSRAYLPDGLHPSVEGNRVMADTAARQRFLHQNPGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGT3</accession>
    <name>A0A010ZGT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type cobalt transport system, permease component CbiQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0038</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441223.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056469_2_0_0"/>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="252" mass="26784" checksum="80CCA654C432BC81" modified="2014-06-11" version="1">MNGLFDCAGGDGFIYRLNPSVKILIAFAAGMAAFAVKSITGALFIAALTVAAAAISGLGRKALSMALLLVKISTLLFVIQLLCARGGQVIFAAGPLMITDEGLRFSLLMVAKLIAASLPLMLALSATQRGDLANSLVQNCRLPYRYAFALTATLKFIPTLASEMAQVMEAQRARGIDFEVRNPLKKAALIVPLCLPLLLSCVRKIENSAVAAQLRGFELRRRESGYKRYPVGIKEAAAAAVSAVGFFVAFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGT8</accession>
    <name>A0A010ZGT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708565.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_859709_0_0_0"/>
    <dbReference type="OrthoDB" id="1353616at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459043" evidence="1">
        <location>
            <begin position="25"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="323" mass="35312" checksum="92327CE07595AB75" modified="2014-06-11" version="1">MRIKYKGLPAALLLLGFTVFPASGASVPKAMDVAKSPLHKNYFEIPVAVVPRAGYNFKKTESGVADNAKKVSLDAVLLHMPYTRLLDEITNDCLKKGNMEVKSRSSFIWNGSAAELLKIFQPNGKTVIGKWVLIVDRGADTCWMISGAYNAKDTKAAQAMLDTIKSSWWPADGTGRPAAAATLPANVNTKGTPFRIAGFRQDSLIYTKDGRIPTQDPDQALYVISHVPGQYIPTEKRGSFAEEHIADVERGAKLEIISRTQETVNGLPAIVTVAYTEGEPQSLIYQAVIFKSSKVTLLVGIARKNIPKNLEAFHKLTASYKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGW1</accession>
    <name>A0A010ZGW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441247.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.82"/>
    <dbReference type="HOGENOM" id="CLU_034446_2_1_0"/>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="5">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="4">
        <location>
            <begin position="160"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="391" mass="41609" checksum="4466BDA36A0BB911" modified="2014-06-11" version="1">MDYRAESLKLHEQWKGKLEVVATVPVKTKDDLSLAYTPGVAQPCLEIQKDVERSYDLTRRHNLCLVVTDGTAVLGLGDIGPEAGMPVMEGKCVLFKTFGGVDAFPLCIKSKDVDEIVNTIYLISGSFGGVNLEDIAAPRCFEIEKKLKEKCDIPIFHDDQHGTAVITLAGLTNALKVVGKKKEEVKVVVNGAGAASISITKLLLSDGIKDVTLCDRTGIIYEGREKGMNPIKQEMALVTNVKKQQGSLADAMKGADVFIGVSAPGTVTQDMVRSMAKDAIIFACANPTPEIYPDEAKAAGAAVIATGRSDFPNQINNVLAFPGIFRGTFDVRASDINDAMKIAASRALAGLISDEELSADYIIPAAFDPKVGPAVAKAVAQAARESGVARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH09</accession>
    <name>A0A010ZH09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Cloev_0116</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441306.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.128"/>
    <dbReference type="HOGENOM" id="CLU_013350_2_0_0"/>
    <dbReference type="OrthoDB" id="304844at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003373">
        <property type="entry name" value="Fe2_transport_prot-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041069">
        <property type="entry name" value="FeoB_Cyto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17910">
        <property type="entry name" value="FeoB_Cyto"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00437">
        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 11" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0410">Iron transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="550"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="12">
        <location>
            <begin position="2"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG78014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="720" mass="78300" checksum="5028C29E694746B7" modified="2014-06-11" version="1">MIKKIALAGNPNSGKTTLFNALTGANQSVGNWPGVTVEKKEGVLRGKKDVRIIDLPGIYSLSPYSPEERVARNYLRDETPDAIINIIDGSNLERNLYLTTQLTELSIPVVAAVNMIDVVKKRGESIDCAKLSKKLGIPVVEISALKGTGLDALVKKAYVAAEEKTVPVVKRIFQGSVEKALAEIELAFADTLPADRIRWYSIKLFEGDPDVMAELKDNVRGIETANAVRERCETEFDDDAESIITSERYAYISALIKESHKRQNESLLTMTDKIDAVVTNRVMALPIFAAIIFAVYYISVTTVGAFVTDWTNDVLFGEIIPPAAEGILAALNVADWLQSLVLDGIIAGVGAVLGFVPQMLVLFALLAVLEYSGYMARVAFILDRIFRRFGLSGKSFIPMIVATGCGVPGIMASRTIENEHDRRMTIMTATFMPCGAKLPIIALIAGALFDGTWWVAPSAYFVGIASIIISGLILKKTALFAGESAPFVMELPDYHMPSLFNVLSSMWERGWSFIKKAGTIILLSTIFVWFTSSFGYADGRVVMVEDLSDGFLAAIGRSIAWIFAPLGWGTWQSAVAAFTGLVAKENVVGTFGILFGFAEVSEEGEEIWQQLAAHYTPLAAYSFMLFNLLCAPCFAAMGAIKREMNSTKWTCLAIGYQTGYAYAVAFVAYQLGLVALEGKPFTAWTAIAAAVLLAAIYLLVRPQKKDSAAIDGRVRAADIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHA3</accession>
    <name>A0A010ZHA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484787.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070028_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37311">
        <property type="entry name" value="PTHR37311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="246" mass="26133" checksum="E6ADDCD636E1CD60" modified="2014-06-11" version="1">MKYIFDVAFLPSEVLKEHDVRVVVDLLRATTQITTFFDGGGNVLVPLRDVDEAFRMKERLGEEWKIMGERGGLPAPGFDFGNSPLELLDAGVPEFAIITTSNGTRALMRAADGCGRVLAGCARNAEAVCWDAICSGKNIGIVCAGRNGEFSLEDTVCAGMLVEKLLALAPANGAEEMELTDGAMSAMALWHSFGPDITAVCQESTHGKILSGLGFDNDLFFCGEVDASSTVPVLKDVDGVPALVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHI4</accession>
    <name>A0A010ZHI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484800.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_3_0"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="210" mass="24102" checksum="6C522FCF596C9DDF" modified="2014-06-11" version="1">MRRTKVEALETKARILESALDIFSVKNFASTSLLEIAQNAGLSKGALYWHFKNKNDLLIQLVKSTCREDGEAFLGLFEERDCGDALRGYYKRALARLFEDARYKKIHGMMLRRRYEWPEEVQTQVRQLVSDSMERDRQMAERLIARGQREGKIRKDVSAGKVALLISSIFHGLYAIQLCGKLPGEFPEYTDILFDAFDRELSACGGRRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHX7</accession>
    <name>A0A010ZHX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709111.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.454"/>
    <dbReference type="HOGENOM" id="CLU_153062_2_0_0"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="106" mass="11893" checksum="31D8AF5FF67E399E" modified="2014-06-11" version="1">MELIQKHPILDYKHGREVTFTFDGRELKGYEGEPIAMALHANGVLIYRVTPEMKRTRGFFCAIGKCSSCFMVVDGVPNVRTCVTPLSAGMKVETQRDKGRVPMEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI37</accession>
    <name>A0A010ZI37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441732.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1040927_0_0_0"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="267" mass="28755" checksum="66BE62EC2D9ABDA2" modified="2014-06-11" version="1">MRDFGDINPAVYLLSRLGTASGLRDGVSVALSGQWSQEPAVAVGLSDMVTYDPSKNATIYLESGVEKTEYAGNGVYKVRAYATAATSGGQSTWGVNERIPASGFYSWDYNSPASPPITYTFGWFGTMPNIKTIIFSLEIQSARKDAREWYGCGSIANIYVDYIDQASGTMKSLGVRTVTFSLNSHPLVNEIYQLYNIKATLNSLASNVRVRVVISNSAESFGGMNWGLGGYNANEYVRFLGGVVQKDPAAGSVTTYSGNVFALAVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI54</accession>
    <name>A0A010ZI54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0508</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709613.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_5_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="246" mass="27576" checksum="0869E7150FDEAC3B" modified="2014-06-11" version="1">MDPILEKNIPPVMPVKAERLSSQISKLILSEIQSGQLTVGDKLPPEIELAQRYGVSRTILREAIASLKNEDILESKQGRGIVVKNARSRQAFRFSDVFETISMDEINYFYEMRALLESEAAGLAATRRTQEDIEEIMASFREMEEAVSDKAPGAEAHDRYNAAIARASHNPVLIEFILFLQGKLHDLAKELRIRTMASPERAHNVLEEHRRVVKFILAKEAAAAQEAALTHLKNAAERAGIKIYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI63</accession>
    <name>A0A010ZI63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoesterase</fullName>
            <ecNumber evidence="3">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0518</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709625.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063749_1_1_0"/>
    <dbReference type="OrthoDB" id="1355703at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00841">
        <property type="entry name" value="MPP_YfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041802">
        <property type="entry name" value="MPP_YfcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="4">
        <location>
            <begin position="10"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="190" mass="20679" checksum="C41E362770D941D2" modified="2014-06-11" version="1">MSVVTIDDKKIGVLSDTHGSFPAWQKALALFGPEVRTVLHAGDVLYHGPRNSIPGGYTPADLLEAINGFQRDGGRVLLAEGNCDAAVDRMVLDPEMEKYVSLVWRGKKILMMHGDNFPLLREMALHNGVDLAISGHTHVGSLVREGGVIFLNPGSTTIPKGRDPESAALLDDEGIRIMTLDGGELHFERW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIA0</accession>
    <name>A0A010ZIA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441817.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016083_0_0_0"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="419"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="8">
        <location>
            <begin position="502"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="641" mass="72722" checksum="DD034BC62B7DD531" modified="2014-06-11" version="1">MPEEKRYVVKNIYGILLVPCFIALAAFVSLLVFSAAITRLTEENTFSTLVDSTEQQVMLFNVSIEGQIRMLTTLADNISVEISKVGDLKEIIPRLEMMKYSSNFLNVGVFGRDGRGYLSTGDRVDVSGRDYFQKSMLYQTVVEKVDSGLVAKKPRFIISVPIINGNSVDGVLFGSYDFSRFKSIAKIDVFDVSSYSFIVDEDGRVVIGTDNRNFLLDNEMLSGTKHMDNFLELLRNSRLDRIDTFEGFMKNFKSEHGGIFGYSFRGNRRYAVYQPLGVNGWYLFNVIDAAVVDGQKNRILHLAYMIIGMVVLCSALFIVYIYKLNAKKNCELMMEEERLRQSEELYRIAANLSDAVLVVVDIANDTVRYNKNFEEKFGYKPRFFTSHELDEHFLSQVFEEDREMVRRYMTDIDCGDRQHALDFRAKNPAGEFFWIRVEFAKLFDSYGKLQRVICRLTNIDEEKRSLQQLRTMADSDALTGMLNRKAAVERMESFLDGEGASGIHAFFIIDIDNFKEINDRFGHIEGDRVLTALAGDMLHFFRDSDIVGRLGGDEFIVLLKDVRSPETAAAKASAFCEHAKRIKELHKLESYVSVSIGVSVAMDGAKGFQLLYREADEALYKVKADGKGGCALYEDKNGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIH5</accession>
    <name>A0A010ZIH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441887.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_5_3_0"/>
    <dbReference type="OrthoDB" id="2061355at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="66" mass="7209" checksum="C316A37844CA2A31" modified="2014-06-11" version="1">MAEFKLKVPDMSCEHCEKRIREAVSNAGGRVKSLDLKSKEVVVDIEAEADKLLSIIDEAGHDAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIU8</accession>
    <name>A0A010ZIU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/proline symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0737</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441981.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="494" mass="52612" checksum="7A67F965E76DED37" modified="2014-06-11" version="1">MFAYAAIIGSFLLLMIVLGLYVSRRVDSADDWAVAGRSLGVVVSTGTYFATIVSSVSVIGYTGYYYELGWGGFFNWTGAVISSSLLALWFAGRIRRYGKVTLADYFEERFGRTNGLICAVIVMGSAFVLLCAQLVGMGAMLNTLFGFNPVISVLVLSVVFIIFTVVGGMIAVAYTDTLASFIIIIGLYIMMFIMLGKVGGFGALHATLAETNPKFLDPFSGGDMKWPLIISWGIVNGVGNIGAAQYVTRFYSSKDENTARTCQGITPVIMLLAFIPLMLIALSASILIPGIKSANVVMPTILLTQMPVFAGGVVASALLMASISTADSVLLLAGTTASRDIYQKYINKNAGSDELLKISRWATLGIGVAAMGASLFMSASVLWIQTNMQNVICSTLALPVIAGFVCKRVNSTGTLVGMIGGGLTAMVWFAIKQPFGVMPSVPGLAVCAVLMFAVSYATKAPSAETVETFFGEGQFDEEDEKEIKRILDCRSING</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIX1</accession>
    <name>A0A010ZIX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CRISPR-associated helicase, Cas3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0757</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the CRISPR-associated helicase Cas3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.809"/>
    <dbReference type="HOGENOM" id="CLU_009347_1_1_0"/>
    <dbReference type="OrthoDB" id="1149839at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035011">
        <property type="entry name" value="Cas3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006483">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038257">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006474">
        <property type="entry name" value="Helicase_Cas3_CRISPR-ass_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF5">
        <property type="entry name" value="PTHR47959:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18019">
        <property type="entry name" value="HD_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01587">
        <property type="entry name" value="cas3_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01596">
        <property type="entry name" value="cas3_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51643">
        <property type="entry name" value="HD_CAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD Cas3-type" evidence="10">
        <location>
            <begin position="9"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="278"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="790" mass="90769" checksum="C0837736B5BE318E" modified="2014-06-11" version="1">MTRYYAKPLVGEEGSYEYHVTRCLEVANNFFKVNRQAIESFCQINGLSCDVMKRICFMAIFLHDLGKLGTSFQNRMEHIVNKVSGKELVYFRHELISALILWQRYEYFGGKYSAEDFPYEIFAVLGHHKGLDKKWQSFEREREKQADKISREALAFALAVEFPHKDLIKELLDGICFDENLFAYREDTNENWVEYFFRHLDKHFKRTSLDRLKDKDRLTRICTFVRGVLCYCDWQASSSGSERLSFSHGYDSEIMESKINAAMLAENGKPFIKRNFQCRCCRKKGNVLAIAPTGSGKTEAALLWATCVASNKIILLMPTKVTSNSLYERMIKYFAEADCGITHSGAAMYLSMSKGDSYGASDEEHGDVFKLLNKYRTFMAPVTVATVDQLLSANFRVGHWYLKEIATLGASVIFDEIHSYDPYMLGLITKSIERIMRMQGRVMVMSATMPRALREHFQDLLGVDEPITADELMGRSNCTWEYTDNSIEGYMAEIKDALAAGRKVAVVVNSIGRAQELYRMWERELEGTELADKIMCYHSAFIMRDRIAKEEKLIGTGKRDEYGRPKEISLIIATQTIEVSLDISFDYMYSELAPLDSLIQRAGRCNRKGNIEGARFIVFPISDVAQKYVYKDAVAIIGKTDEILRKRQGKLSENEIGAMLEDAYQNYSFTDHKDYKTARDNIEVIWDERAPIFDTVDYNEECVTRLISYVKVPIIPQKFYGEVTELCRSGEKKDKLKVALYEVPVGMKTLKLFNNKKCVMPPDLAYLDIYEIPYDEKIGVPSNNDDPLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ56</accession>
    <name>A0A010ZJ56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710769.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.879"/>
    <dbReference type="HOGENOM" id="CLU_024839_0_2_0"/>
    <dbReference type="OrthoDB" id="1413173at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="276" mass="29449" checksum="892DAB8F74891132" modified="2014-06-11" version="1">MTQESCSHDCGSCEQKCAEAEKPDFSVPANPLSNVRRVIGIVSGKGGVGKSLVTSLLASAMQKRGNQCGILDADITGPSIPKMFGVETLASANESGLLPQQSKGGIDMMSVNLLVEDKATPVIWRGPAIAGVVKQFWSDVIWSYEDFLFVDMPPGTGDVPLTVFQSLPVDGIIIVSSPQELVSMIVEKALRMAKEMDIPILGIIENMSYIECPDCGKKIKIFGEGRTAETAAKYGIDFLGEIPLAPEIAALCDAGNIEYFSDACLDRAAAKLESLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ78</accession>
    <name>A0A010ZJ78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Saccharopine dehydrogenase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710807.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032858_3_0_0"/>
    <dbReference type="OrthoDB" id="1006830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_C" evidence="1">
        <location>
            <begin position="125"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="393" mass="44209" checksum="FADF6067DFDCE85C" modified="2014-06-11" version="1">MAAKKKALHIGAGMVGRCVVHNLLPYFDVRVLDMSDENLEETKKLYPSVEVVKGSALDKEVVSKASEDCDIITAAMPGTIGYKVTKLAIELGKKIASVSAMNGRSDAPYHEIGLRTGGLGISMVGFEPGMSSFFAGRGYYRLDKCEEMYLYVGGGLPINPRPPFNYFTTWSLYDNINQFNQPATVVRGGEAKRIPALSEVMPFEIEDYKDLECFTSDGLGGLFRCFKDVPEMAAYTVRWPGIAAQMRFLNELDLFDEEERRLGKVDQVPRDILMDIFGKKYQRLPGEEDMSILRIVTKGIKGNDRVTYTFEIAQREIPETGYTSMAWTTATTCAIFARAIADGKLTGKGILNCEQLARDDEFYDWVLEEQRKLGIFYKEKVEIEKNAKLWENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJJ1</accession>
    <name>A0A010ZJJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442243.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544944_0_0_0"/>
    <dbReference type="OrthoDB" id="1966324at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="173" mass="18584" checksum="AEBE10A9ABD6FDF0" modified="2014-06-11" version="1">MPEKRKIFLPFAPSDLSAAAELIADGAVYYTCAVPEMAAELEKRLREMSGCAGGCVTGEMTLEAIAPAVVGCAENLGAIDRLIYMPELTARGELFLDLSEDDFTAHTAAINGLFMLCKCALPYMMGGESPEIIVRLPHGQSNLISEMYRSAAEAVAKSMNNELAEYGVLVKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL06</accession>
    <name>A0A010ZL06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708563.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.51"/>
    <dbReference type="HOGENOM" id="CLU_094090_0_0_0"/>
    <dbReference type="OrthoDB" id="1918022at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="192" mass="20058" checksum="1365BB66CB58CC77" modified="2014-06-11" version="1">MNSTETGRERTAMVEERSAGLSVAQIMLVAVLLAAGAVMKFFIGSIFSAGMKPNFIIAMYCLAILLVRPRFKEAAIIGLLAGAVCQFFPGTPYLNFPSELAGALVMALFARMDGRAGGFLMPAVSTFVTTVVSGGVFMALLYALFFSGGTTAPAPLAVFAGIIFGTAAVNSIIVQVLYIPVSAALKMRAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLI0</accession>
    <name>A0A010ZLI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-dependent hydrolase</fullName>
            <ecNumber evidence="1">3.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.9" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.248"/>
    <dbReference type="HOGENOM" id="CLU_030671_3_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="246" mass="26537" checksum="DE5C123D08B0936D" modified="2014-06-11" version="1">MLPDAKKAEYCPGRSGKAILYTPRLTQGRMDDLRVIDLGRPIEDSMQVFPGDISPVVEEFAEMSDAGFRTKKITMSSHTGTHMDAPAHMLADGARLDELPNDTFFGFAVIVDVSGRAGREIESADLGLTKEEMAAADFLLLHTGFEDKMGSGAYLKDFPVLSQETARRLTEAGLKGIGVDAISVDPVESEECPIHKIILGGGMVIMENLRGLCQLPFKVPFCLTALPLALKGADGAPVRVMAVLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLK8</accession>
    <name>A0A010ZLK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase component of uncharacterized ABC-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441427.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_0_0"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="261"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="512" mass="55683" checksum="495A114F06A2C9C0" modified="2014-06-11" version="1">MTETKKTLVSMRGVDKIFYGKHANKGVDFELLAGEVHSILGENGAGKTTLMNCLAGIYLPDAGSIYIEGEPVFLPNPKAAIGHGVGMVHQHFMLVPVFTVWENIILGLGDIPLVINKEKIIARIREISDRYSLAVDPEAKVWQLSIGEQQRVEILKMLYRGTKVLILDEPTSVLTPQETRELFKTLKDMVAAGHGIILISHKIEEIMEISDRLTVLRKGVRVATREAAGVSKAEIAEMMVGHSLEGTSLPEDRRKPGGTVLECSRLTLKDERGTEALKGVSLAIRGGEILGVAGVDGNGQDELCEVLAGLRSPDSGSVSLEGNDITSEGTRGCIEKGISYIPADRKGVGLVANMSIIGNIALKGYCRPPMEKNKFFMDWAYITDFAAERVKDYDVQIPDLFAPVRVLSGGNLQKLMLSREISEETKVIIAMQPTWGLDVGAAEFVHKRLIEAREAGAAVLLISKDLQELTALSDRIAVMYSGEISGVVDDPRSADIEKIGLLMAGVRDKDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLL4</accession>
    <name>A0A010ZLL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase superfamily enzyme, subfamily IA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484797.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037089_0_0_0"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="268" mass="29468" checksum="550DDF56D62DDAAE" modified="2014-06-11" version="1">METNFKADALIFDIDGVLLDVARSFPEVIRQAVFGGWEKFCGGISDTPGYNAGHERVLKRHGAFNDDYDIAWTLLSMAAASGEKLLSKALPSPERLYSELEDCRAPSHEWAAARYGALVPRRDVRELCAELYGGKGYGLHLLEKPMIKMHWKELGLPAAIYSGRNDLEWELGKESLGWEDFPDELIINSDSGITKPSPEGLEILCRRLGAASPVFFGDTASDMQAQAAFGRGRFAAVGHLLPEAEFRYDTTEEAVRASVAAGLLTDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM13</accession>
    <name>A0A010ZM13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative MobA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484818.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061980_1_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="192" mass="20972" checksum="3A741F593AC5D487" modified="2014-06-11" version="1">MNVILLGAGLSKRMGRQKLLLPFGDRSVIETVIGNLRDAGARMIYAVLSREVAEALGPAAGPLTVRVNEEPERGQSSSLSIGLDMLPAGEDFCIMLGDLPLARAADIAALAERFKALPPEKSVLAPCRGGAFGHPMFYRALWRERFRGAEGDVGGKKILMRYEGEIERAEAPDCHFKDMDTPEEYQERLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM34</accession>
    <name>A0A010ZM34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441598.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031290_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458213" evidence="1">
        <location>
            <begin position="25"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="427" mass="44777" checksum="F731DB39FE4D85E0" modified="2014-06-11" version="1">MRKKTLSLLLIIALALFTVLPASADVLFTRQTNYSNTALGVINGSGAPVSPLIGNMGGDSGQGIFGFTNAEGGYRVAISLYGSGAAVDTINVYSPGAEEDWSKADVWAKPAAEITTSLFNTRAMKAMNGYLYGISYANAVVSKISTSSDDYKELATLEFEPQEGYSGHGEGLVTYNGSVYAIFSASKGTYGNYSYLPNTLVKLDADLNETATLPLAGLNFDGGGQGAYALSGSTLYVTSVGGSQPYGTLNEASSIEAADLDAMTTKTLVTAADVYKKDNTFNHFFKAVVVAGDKIYIKAVEWKADFSGYSMRVYETTAEKLAAGDIGTMIKDFTGTGWAAGMSYDSKTGYLWVAAGTSLNRYDGAAWTTYDKDALQGDLAQFAVANVPSAPTPDSGSSGGCNAGIPTALMAIALIPLLIRGKRSAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM41</accession>
    <name>A0A010ZM41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441608.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2192421_0_0_0"/>
    <dbReference type="OrthoDB" id="2138668at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="108" mass="12233" checksum="9CFA634E0B050825" modified="2014-06-11" version="1">MINKKIVILMILAAVLFAGIPFIVGALSGGREVPLLEQAREYISAGSSAEFIAHFSAFTGLAYWLFSGSWDFFWEFDDEGLWDFLFDLFHHGPEKYKFERDAPGTFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM62</accession>
    <name>A0A010ZM62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the carbamate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709156.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.482"/>
    <dbReference type="HOGENOM" id="CLU_076278_0_0_0"/>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008804">
        <property type="term" value="F:carbamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04235">
        <property type="entry name" value="AAK_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003964">
        <property type="entry name" value="Carb_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409">
        <property type="entry name" value="PTHR30409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000723">
        <property type="entry name" value="Carbamate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00746">
        <property type="entry name" value="arcC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="331" mass="35657" checksum="541FAB72BE7869DB" modified="2014-06-11" version="1">MIPHPIATNDNPSKATKVVIALGGNALMEAGTPPTAEEQLKVVKKTCDNLADISCNGYEMAVVHGNGPQVGRLVLQQEIAAASQPDQLPAIPFDCCGAMTEGYIGYQIQQSLRDALRNRNRNVPVVTLVTQVIVDESDPAFEKPTKPIGRFYSAEEAEKVAKEKGWTMKEDSGRGWRRVVPSPKPKRIVELDSVKRLWDSTIVITAGGGGIPVIENMDGSLSGVAAVIDKDLAAERLAEDMETDILLILTEVENVYVNFGKPDQKALSHITVAEAIQYMEEGQFGSGSMEPKVMAAIKFARRFPGKKAIITSLAKAIDALENGAGTIITMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMA1</accession>
    <name>A0A010ZMA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441738.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1892542_0_0_0"/>
    <dbReference type="OrthoDB" id="1973128at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="134" mass="14488" checksum="23225EF2F5C3B667" modified="2014-06-11" version="1">MAQNKTIKIDAGADYFLTVRLRDEAGELIELTGCSARMKLKKEYDSADAMVSLTSDAGGGITFERFDDDSAFVDACCVHITNVQTGPLVDYSIKDGDGEVQPGEGVYDLEIVDTAGVVLRAINGMWIAMQEVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMF2</accession>
    <name>A0A010ZMF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0547</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="228" mass="25710" checksum="D77393DBDCAC8C13" modified="2014-06-11" version="1">MIQAISRVTLTQSISDQMLKLIKDGTWKPGDKIPSENELASSFSVSRNSIREAVKILNKMNVLTSCPGQGTFLAQDAVSRILSLEVIDIGYKNASVEEIYEIRTLLESQSAYWAALRVTDDDIDELNDLLRLSRDNENRDIAEQNRIHYAFHDAIIRMSKNTLLIHMLSSIKAEIDAHHASFDNLPAADITNLINDQEKVIAAILNKKPEEARLAMISHLERAMRLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMH6</accession>
    <name>A0A010ZMH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441825.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.615"/>
    <dbReference type="HOGENOM" id="CLU_028255_0_1_0"/>
    <dbReference type="OrthoDB" id="1292731at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006078">
        <property type="entry name" value="GlxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="388" mass="39935" checksum="BE0DA4CEF8C19BFF" modified="2014-06-11" version="1">MKRFILIPDSFKGTMSSMEICGIMAEAIKAHIPDAGVRGIPVADGGEGTVEAFISAVGGEKRETAVTGPRFEKISSFYGALYDGKTAVVEMSAAAGLPLMGSSLDVLGSTTFGVGELILEAVRGGAGQVIIGLGGSATNDGGCGAAAALGVVFRDGEGRPFVPTGGTLSSIASVETGGIAPELKDVRITAMCDIDNPLYGERGAAYVFAPQKGASREVVQLLDAGLKHLNETVKRCLGADRAEDRGAGAAGGMGYGFAAFLGAELKMGIDVVLDAVDFDGLLKGADCVFTGEGRIDSQSLGGKVVIGVARRAKRRGVPVIAVVGDVGDGIGGAYEEGVSAIFPINRVAVPYSEARLRAKSDLRLTVEDIVRLIKTAELRQSDVRRLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMZ1</accession>
    <name>A0A010ZMZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441987.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058393_1_0_0"/>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="361" mass="39937" checksum="FF965D1F989AC9DF" modified="2014-06-11" version="1">MASRVLSVKTKYMEFESHVGEIFDFAGMELSGKRVLIKPNILYYTEDEQARNTNPTMVEAVAKECERRGAARVQIGDNAGQMLYGNSRDAFDVSPGFADRMARYYVNLGIDLVPVRLKSAERTVYLSKALFEADVVINMPKFKTHGLTGVSAALKNTFGYVPGGQKARLHVILGDYDPFDRLLAEIHSIRRPDLNIVDSVLCMQGRGPFSRYLYYAGHVVVSTDPVALDSALCRMIGLDPHTIGHIRYANQMGLGDIDGCEMVGELPFIDRYLLPPGFDGERKLNPVFCSQSINIDGHRTNFTLDRAKCVRCGKCIEQCPVGAIEPAEGYPRATGRECVSCHACQEVCGAKAITIESTYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN44</accession>
    <name>A0A010ZN44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442028.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.837"/>
    <dbReference type="HOGENOM" id="CLU_017779_9_2_0"/>
    <dbReference type="OrthoDB" id="1188552at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="48"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="476" mass="52203" checksum="72C4F2509F7A734D" modified="2014-06-11" version="1">MNDLFSYNKITVEIIEALKEKIGANNVCADEEKLETYSHDEVPQSAYEKKYTAELLLFPESTAHVSEIMKIAHERKIPVTPRGAGTGLSGGALPAWGGIVMSFEKMNRILELDEENLTITAEPGVVTAEISRTAAQHGLLYAGDPCSGDASFIGGNIAENAGGNKVIKYGATGAQLLALEVVLADGSVTWFGGKRRKDVTGLDFVHLMAGSEGILGIITKAVLKLMPLPRHSVDLLAAFPDARSAIDFVPRIITEGGLIPASIEFLDQKALKLTERYLNTQVPAGDAGAALIIQLENNDAGLIEKEFEEIGKLSQKHGASEVYVADTRTTKDRIWQARKAVPEAVSFFYSRYTKEDLVVPTALVPQLLEMIREKAEADGLEWIAYGHAGDGNMHCTIISPDCEDWHERLHAVQERIYAELLKMGGTLSGEHGIGFKRKGYMKFFLNEAQLELIKRVKLAFDPQNILNPGKLVDWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNC7</accession>
    <name>A0A010ZNC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NhaP-type Na+(K+)/H+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0851</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442071.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.907"/>
    <dbReference type="HOGENOM" id="CLU_005912_9_1_0"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030151">
        <property type="entry name" value="NhaP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32507:SF7">
        <property type="entry name" value="PTHR32507:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="402"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="486" mass="52042" checksum="73CB644434B40E85" modified="2014-06-11" version="1">MDNINALILFVSLILLFCIAFSRFLTKAGIPVLVFFIFAGMIMGSDGVGGIYFDNAVVASTIGNFAICYILFAGGMATSWKSAKEVLAPGVLLSTVGVLITAVFVAVAAYFLVGLTWLQGLLLGAVVSCTDAASVFSILRSNNLNLKAPLAPLLELESGSNDPTAYMLTIAIISLMTAPDNGFLSFAMMFVVQFSVGGALGFAFGFAGAWVTNRIKLNSDGLYPVVAATIAALIYSAVQIMHGNGFLGIYVAGMVMGNVKLAHKVSLVRFFDGFSWLMQILVFVTLGLLVFPSQLPSVWLPAITISVMLMFVIRPAAVFLTLLPFKYPRNARLLISWVGLRGASSIVFASYALSNSLPNADVIFNMVFFISLTSVILQGSLLAPVASLLDQLDREDKTLVSRGFTDYEEELQGTLYELRAVKGSPAVGMAVQEMKFPESVRIMLISRGSGTLTPTGKTRIKEGDMLMVTAENTGVLLALKERLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNE5</accession>
    <name>A0A010ZNE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type Fe3+ transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0867</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442097.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.930"/>
    <dbReference type="HOGENOM" id="CLU_021838_1_1_0"/>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="516"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="64"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="348"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="556" mass="59720" checksum="BAE42384D3B3CCE7" modified="2014-06-11" version="1">MASSSSMRRDPALLPVVAALWLALGFFVVYPFVKLLITTFIVDGRLSLANLMLVFSNGYDRLAFVNSIWLAVAVAVMGTFLGFVFALAVTRINLSAPLRWFISAVTVLPLISPPFTSSIALTLSLGPNGIILKFFGIPDFNIYGFWGTWISESLTYFPVAFLTITSVLACIDPNLEDAGLSLGGSPFRVFRTVTFPLTMPAIANSILLLFACSLADFATPLVLAGHQFPVLPTQAYLQITGMYDLKGGAALSFALLVPALLVFVLQRFWVSRKSYVTVSGKSGAQTKIKGIGTAGEAAVLAICAAVISFILFLYALIVMGAFTKAWGLDNSFTWESFAYVFNHGRKAMLDTLIIACIATPLGGLLAVSIAYITQRKSFWGNGLMEVVSLLNFALPGTVVGIAYIIAFNSQPLVLTGTMSILVAAYVFRYDSAGIRSVIASLHQIDPSLEEASLSLGASSIGTFKNVTLPLVVPALLAGMKYLFIHSMTAISATIFLVSVSWSLLTARILECMTELQFGNACAFSVVLILLVFIFNGMLTLLVRGAGYNYRGQGGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNI5</accession>
    <name>A0A010ZNI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Cloev_0901</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016220">
        <property type="entry name" value="Me-P-triester_DNA_alkyl-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000408">
        <property type="entry name" value="Alkyltransferas_AdaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="9">
        <location>
            <begin position="72"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="179" mass="20502" checksum="C8327DF2C32E6B2C" modified="2014-06-11" version="1">MYEAVITNDANYDGSFFYGVKSTGIFCRPSCQSKKPLRENVCFFHSAGEAMKEGFRPCKRCRSDLLSYRPMEKIAGLVKKHLDELYERQTSWNGELREIGLSERRVVQIFKDVYGMTPKAYMDILKLREAKRLLSETDKKVIDIAASVGFGGLSAFNRFFKEQAGCSPAAYRKMYKKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNN7</accession>
    <name>A0A010ZNN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tuf</name>
        <name evidence="10" type="ORF">Cloev_0977</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708477.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1047"/>
    <dbReference type="HOGENOM" id="CLU_007265_0_0_0"/>
    <dbReference type="OrthoDB" id="621774at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="396" mass="43634" checksum="5482AAA6A29DD060" modified="2014-06-11" version="1">MAKEKFVRNKPHLNIGTIGHIDHGKTTLTAAITKTLARHGGADFTPFDMIDKAPEERERGITINISHVEYETPARHYAHIDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHVLLARQVNVPALVVFMNKCDMVDDPELLDLVEMEIRDLLNKYEFPGDDIPIVRGSALKALESDEDNDWTKGIMDLMQACDDYIPAPEREVDFPFLMPIEDVFTITGRGTVVTGRVEKGIIRPGDEVEIVGIKDTHKTVATSLEMFRKILDDAEAGDNVGILLRGVGKDDVERGQVLAKPGSIKPHTHFKGEVYVLKKEEGGRHTPFFSGYKPQFYFRTTDITGEIKLAEGVEMVMPGDSSTFEVKLIAPIAMQEGLRFAVREGGRTVGAGVVTEIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNR4</accession>
    <name>A0A010ZNR4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="10" type="ORF">Cloev_1007</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711027.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A010ZNR4"/>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1076"/>
    <dbReference type="HOGENOM" id="CLU_092403_0_1_0"/>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="98"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="208" mass="23345" checksum="10F7D82B9780782F" modified="2014-06-11" version="1">MSRYTGPVCRLCRAEGAKLFLKGDRCYTEKCGLTKRNSKPGQHGTRRGKMSEYGIRLREKQKLRRFYGINETQFSTIYKRATGMTGQTGHNFLQLLERRLDNVVYRLGLGVSRSQARQLICHGHFTVNGRKLDIPSALLKVGDVVAVAEGSRDVPTIKENAEASASRSIPAWLEFNPEAMSGSLVAVPVREQIDVPVNEQLVVEFYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNR8</accession>
    <name>A0A010ZNR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type cobalt transport system, permease component CbiQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_1012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711032.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1081"/>
    <dbReference type="HOGENOM" id="CLU_056469_2_2_0"/>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="270" mass="29375" checksum="592CDDF7CD9E4D09" modified="2014-06-11" version="1">MAAFDKIALGQYIPAKSPIHALDPRAKIILVISAMAAVFMTHTLTAFILWGALLLLIARLSRIPPRVVAASARPVLILIIFTSLLHLFLTPGDEIARFGRLTVTKEGAFLALTMSMRLACLVMYASLLTFTTSPSQISDGLEGLLSPLKRVGVPAHEIAMMITIALRFIPTLFEETGRIIKAQKSRGAEFDEGSLMKRAKAYIPVLIPLFVIIFKRAESLAVAMEARGYCGGAGRTRMKPLRWRPSDSAALAAFILLSAVIVCGEKVFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNU6</accession>
    <name>A0A010ZNU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfur carrier protein ThiS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711087.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174611_3_2_0"/>
    <dbReference type="OrthoDB" id="2084255at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="65" mass="7322" checksum="31D048DE5F86F113" modified="2014-06-11" version="1">MITVNGEQSPWREGLTVQQLLDEKNFTFKMLAVWVDDSVVDKSRYSEAKIRDGANVQVIHNISGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNV2</accession>
    <name>A0A010ZNV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711141.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166678_0_0_0"/>
    <dbReference type="OrthoDB" id="1990928at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010398">
        <property type="entry name" value="DUF997"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39174">
        <property type="entry name" value="PTHR39174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06196">
        <property type="entry name" value="DUF997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="11377" checksum="D1C88C25AFD9DFC0" modified="2014-06-11" version="1">MEGRDVASKKFLQATRRETFIILGLYLLFFVWWYVTAYGFGDDPSRYRYILGFPEWFFYSCIAGYAGISFLLWAVIKIFFKELPLSDEKEEVEKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNV5</accession>
    <name>A0A010ZNV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ORF">Cloev_1061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711154.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1129"/>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_0"/>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="185" mass="20998" checksum="693CBEE5368A863D" modified="2014-06-11" version="1">MPQNVLKELTSRCEKSIEHLKGSMLGVRTGRAHPALVEEIKVDYFGTPTPIKNMGSVNVPEARQIVITPWDKTAMKAIEKAIQSSSLGITPQNDGESIRLNLPELTQQRRVELKKMVNKMAEEGRVAVRNIRRDAIEILKKMEKESKITEDDLKKFQKEAQDKTDAFIKKIDSVLADKENEIMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNZ1</accession>
    <name>A0A010ZNZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-seryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5">2.9.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenocysteine synthase</fullName>
            <shortName evidence="5">Sec synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selA</name>
        <name evidence="8" type="ORF">Cloev_1110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22728"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SelA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1183"/>
    <dbReference type="HOGENOM" id="CLU_038142_1_0_0"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004125">
        <property type="term" value="F:L-seryl-tRNASec selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00423">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004534">
        <property type="entry name" value="SelA_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025862">
        <property type="entry name" value="SelA_trans_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12390">
        <property type="entry name" value="Se-cys_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00474">
        <property type="entry name" value="selA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Se-cys_synth_N" evidence="7">
        <location>
            <begin position="10"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5 6">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618319-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="477" mass="52337" checksum="ACBA6158FB602C0A" modified="2014-06-11" version="1">MDANIQKIMRNIPSMDKLLALPWIDGYEKKLGRETVKLLLTELLAAQRARILKDPDTAFDFESIENDARRLLDKKSTPSLRRVVNATGVVIHTNLGRSLLAEEAVKEVLEIAGSYNTLEYSLEEGARGHRNNHVEWLLCRLTGAEAALVVNNNAAAVILALSALANDKESVVSRGELVEIGGSFRIPDIMALSGTRMVEVGTTNRTHLKDYETAITEECAVLLKVHPSNYRVTGFHSAVPREELAALARARGLVFMEDLGSGMLIDTSAAGLSSENDPTVAESLKAGCDIVTFSGDKLLGGPQIGAIVGKKELIEKLKSHQLLRALRVDKMTLAACEATLRLYLRGDGRAIPTVDMIFKTKEELLEDAKRFSRRLKSYFKNTRIQRLMIEVVPVNDTVGGGTFPQSELAGYAVALRLPEMGSAGKLAEKLRRGSHPVITGAAEDKVLFHLRTMRPGDDRRIIDALDEILHMPSERGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7A2</accession>
    <name>A0A011A7A2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/proline symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441211.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_3_0"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG77931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="555" mass="59165" checksum="40644178DBA52F46" modified="2014-06-11" version="1">MGAMDYLRTNSLDIIVLVLYFCVLIGNGIYFSCKKTRELKKAKGGDSGTDSFLVGGKSFGVFATLCTQGASMKGSGALLGYSGGAFVNGCGTLIPGQCYSLGAWFSIACGMARKLRKCADKLDISSIGDVFVARFEKPALRKLSGVAGAWLALSILCSQMAALGLLIHLMFSKYGMTYELALVIGIIVSFTYVSIGGLVSVVYNDVFQWLIMTPMIFIVLPGSMILMHGVTPQAMHSTLDAAQFFSLRPNMWWLGYLLSGLLASCCDVTHVQRFISAKDEKTSVKGSMLGFAYCTLFAGVVTFLGLGAAMLVDPAIIGKNTDGVLFALISEVLPHGLIGLFVAAILATTISTLDSYLQVCVLCLMVDIVEPALPETTTEKQKLFCCRLLTLLIAVAASLLVLQFKGILTIVAVGYSTFSSMMFLPFMCALYWKRCTGSGCVAGMVAGCLACSAGVYLKLPLPIVWGVAASLIAIAGVSFATASEQKPLLPGFNEHGQEIDHSVLKGCVFGTAGSLLISVGFGMYINWIYIIAGIIGMYLCVTMIDKAFKKYTLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7J0</accession>
    <name>A0A011A7J0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain fatty acids transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441311.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.135"/>
    <dbReference type="HOGENOM" id="CLU_037744_0_0_0"/>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006160">
        <property type="entry name" value="SCFA_transpt_AtoE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41983">
        <property type="entry name" value="PTHR41983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02667">
        <property type="entry name" value="SCFA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="439" mass="47563" checksum="52965D544B53D6A6" modified="2014-06-11" version="1">MQKITKFFVRLVQNILPDAYILAVLLTFVVFGAGVVVMGKSPFDMISLWGNGYPSLFVFAMQMVLVLLTGYVLALTPVMEKVVDKLVAIPKTPKSAMGLTAIVGLVSCYFNWGFGMVIGAIVAKAMGRKIKGIHFPLLVAASYGGELVRGPSSSIPLVSATPGNFMTELGIDIVPVTETLYSPWNIILTILIAAALFTYYCTVKAPDDEIIEYKEPLEEAVIAKKEKSAMTFAERLENTYILNILIALFPLTYLVVNFNKLGFNLNLNLVILIFMTLGLLFHSTPMQYLQAVARAITATKGIIVQFPLYAGISSMMVGSGMVESLSLWFVNIATPTTFPMITFLAAGLVNIFVPSGGGQWAIQGPVMLKAASAMGASIPQTVMAFAWGDGWTNQIQPFWALPLLGVVGLSARDIMGYCVIWTIVSGIIICGVFTVLTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7K8</accession>
    <name>A0A011A7K8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tartrate dehydratase beta subunit/fumarate hydratase class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709233.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.155"/>
    <dbReference type="HOGENOM" id="CLU_098588_2_0_0"/>
    <dbReference type="OrthoDB" id="1677478at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase_C" evidence="3">
        <location>
            <begin position="7"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="167" mass="18046" checksum="56F3B35FD876023D" modified="2014-06-11" version="1">MQIKMPVDDETIKKLHVYDMVEIYGPIFTGRDAVLPKVVKCIEEGTCEEKGIFLKGAAVFHTAVSPAGIGPTSSNKLDIEGSIPALSEAGVKMHIGKGSLKKETVEALKKNNSIFLVTPPNTALLTATMKSKRVVAFPEEGMEALYEVEVEKFPAIVAIAHGESIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A804</accession>
    <name>A0A011A804_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081811_1_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041561">
        <property type="entry name" value="PglD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17836">
        <property type="entry name" value="PglD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03570">
        <property type="entry name" value="NeuD_NnaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PglD_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="213" mass="22591" checksum="4F4F0C58E4236D3B" modified="2014-06-11" version="1">MEKKEKVFLIGAGDHAKVVLSTLEACGVECAGIYDDNPELWGRTLWCLPIIGAVSEMPDTPETMAVIAIGSNTARRTIRERFKEVCWPVFVHPQGIVHSSVRIGEGTVVFAGCIIESDAEIGKQCIINSGCFIGHDSKIGDFCQMAPKSAIADSVMLGSGVFLGLGSMVRPYTTILDDVTVGMGSSVVKKLGPGGTYVGTPARRIMTPVVGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A874</accession>
    <name>A0A011A874_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">crcB</name>
        <name evidence="10" type="ORF">Cloev_0331</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709006.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114342_3_2_0"/>
    <dbReference type="OrthoDB" id="1942863at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="123" mass="12824" checksum="59B34F76E5F67E02" modified="2014-06-11" version="1">MEGMLFVGLGGFFGASLRYLLGKAASSQSVIPAATLAINIFGSFMIGVLSLFSERHGLSRHSVILMLQAGFCGGFTTFSTFSLETFALISQGKMGHAALYAVLSVLCCLFSVAAGRTLAGLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8P5</accession>
    <name>A0A011A8P5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Na+-dependent transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709610.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.541"/>
    <dbReference type="HOGENOM" id="CLU_034788_1_1_0"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="312" mass="33006" checksum="517C16BDCFA8B8D8" modified="2014-06-11" version="1">MKFLEKLSDFVGRYMAFIVVVVAATALFEPSALLWIKTSWITTLLMIVMFGMGLTLDPADFAVVFRRPKDIILGCVAQFTIMPLLAFGLGKIFALDDALLVGVILVGTCPGGTSSNVITYLSKGDVALSVGMTSVSTLLAPVLTPALTYLLLKQTVSVDMAAMFMSIVKVVILPIAAGFVINKFFSSTTQKAVRVLPLVSVTAIVMIVAAVVSANSAKIMTTGLVVFSVVILHNILGYALGYMIAAFLKVPLAKKKAISIEVGMQNSGLATSLAASSFPSLALATVPGAVFSVWHNISGAILANIYSQMREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8R8</accession>
    <name>A0A011A8R8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="8" type="ORF">Cloev_0530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441771.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.567"/>
    <dbReference type="HOGENOM" id="CLU_046483_2_1_0"/>
    <dbReference type="OrthoDB" id="1766414at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="131" mass="14467" checksum="628060923B2DEF4E" modified="2014-06-11" version="1">MADKKFLWGTGRRKNAIARVRICEGTGQFLINNREVKDYLPRFYWASQAVEPLAAAGVEGKIDVFVNAHGGGLTGQAGAIRLGVARALLKMYPNVRPVLKKAGLLTRDSRMVERKKVGLKGARANKQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8W1</accession>
    <name>A0A011A8W1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cob(I)alamin adenosyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710300.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.619"/>
    <dbReference type="HOGENOM" id="CLU_088595_2_0_0"/>
    <dbReference type="OrthoDB" id="1690483at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="175" mass="18996" checksum="FB671D37F09FFB8D" modified="2014-06-11" version="1">MFGSKGLIEIYTGDGKGKTTAALGLALRACGHGARVAIVQFMKGWAQYGELAAVKHLPNVTLVHTGRDKCIFRGDETAEDFTEASRGLKEAEKFIASGEYDLVILDEINVAIDFGLIDADDVAELIGRKPEKTEIVLTGRNAPKSLLEMADLVSEIKEIKHPYRSGVSARKGVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8W6</accession>
    <name>A0A011A8W6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Carbon starvation protein, predicted membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Cloev_0584</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441829.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.624"/>
    <dbReference type="HOGENOM" id="CLU_010531_3_1_0"/>
    <dbReference type="OrthoDB" id="457782at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025299">
        <property type="entry name" value="CstA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003706">
        <property type="entry name" value="CstA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02554">
        <property type="entry name" value="CstA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13722">
        <property type="entry name" value="CstA_5TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="CstA" evidence="9">
        <location>
            <begin position="3"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="CstA" evidence="9">
        <location>
            <begin position="153"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="CstA_5TM" evidence="10">
        <location>
            <begin position="320"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="490" mass="52812" checksum="BE6C6B5CBDB94EC6" modified="2014-06-11" version="1">MLTFFIALLTLVAGFMTYSFFVEKLLPPDDRETPAIAHPDGVDYLPLPLWKSFLIQLLNIAGLGPIFGALSGALWGPVVYFWIVFGTIFAGGVHDYFSGMLSERHNGASISEIVGIYLGPQMKTVMRVFAVVLLILVGTTFSTGPAGLLALLTPASLNVTFWLAIILVYYFLATLLPIDKIIGRFYPFFGAALIVMCVGVGGGLVVRGYNLPEMWDGFANLHPRALPIWPLMFITVACGAISGFHATQSPMMARCITNEYQGRKVFYGAMVAEGVIAMIWAAAGVSVYNGTQGLWDATTSLAGQSALVYDICIRVLGPVGGVLAMIGVIVCPITSGDTAFRSARLTLADWFDIDQKPRVKRLLLSVPLLLCGALLSNMNFQVIWRYFSWSNQTLAMIALWAAAVFLCKARHNFWPLAIPATFMSAVSSTYILVAPEGFGPAISRMVSGEALTGAAALKAASAVGYPAGIAFATLCFAAFWFKCVRPNAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A915</accession>
    <name>A0A011A915_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.683"/>
    <dbReference type="HOGENOM" id="CLU_048266_4_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011204">
        <property type="entry name" value="Virulence_RhuM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13310">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="148" mass="16924" checksum="961DEB282761E486" modified="2014-06-11" version="1">MTGGGEIILYQAHDGSVKLEVQTDGETVWLTKEQMGTLFDRDRSVISRHIGNIYKEEELEEESTCAKFAQVQTEGGRSVQREIERYNLDVIISVGYRVKSRRGVDFRRWAGKVLKDYVMKGYAVNDRRAERFVLFFKPSSLAGVRPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A976</accession>
    <name>A0A011A976_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF126 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.757"/>
    <dbReference type="HOGENOM" id="CLU_141583_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002840">
        <property type="entry name" value="AcnX_swivel_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01989">
        <property type="entry name" value="DUF126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF126" evidence="1">
        <location>
            <begin position="33"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="144" mass="15434" checksum="B15F3675606D73B0" modified="2014-06-11" version="1">MADNMKVYKCRSIVRGSGAGEAVVSKDAMCFYLTDPTTGVVIERNHAIEGKSIAGKVLVLQSGKGSSVVQADGFYQLWVRNNLPAAIIINVPEPVIVSSAVMVGSTMVDRLEKDPFEAIEDGDYVEVDADAQEVRVWKGGKAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9F0</accession>
    <name>A0A011A9F0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon dioxide concentrating mechanism/carboxysome shell protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034445272.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115793_0_0_0"/>
    <dbReference type="OrthoDB" id="1759482at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011238">
        <property type="entry name" value="Organelle_shell_prot_PduT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034834">
        <property type="entry name" value="PduT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="2">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="BMC" evidence="2">
        <location>
            <begin position="96"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="179" mass="18350" checksum="F2F285CF97ECC14A" modified="2014-06-11" version="1">MGNAIGMIELSSIAEGVNTADVMVKAANVELIHASTVCPGKYVAIVHGEVGAVRASMKAGLGAAGHYVVDDLLIPNIDPQICPAIMMTTEPGEIEAVGVIEYFSVASAIMAADVAVKAANVRLIEIRIGFAIGGKGFVTLTGDVGSVRAAVAAAAKEEALLVSKTVIPKPSRQLVEKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9G3</accession>
    <name>A0A011A9G3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710710.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.845"/>
    <dbReference type="HOGENOM" id="CLU_033405_1_0_0"/>
    <dbReference type="OrthoDB" id="580055at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004770">
        <property type="entry name" value="Na/H_antiport_NhaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00931">
        <property type="entry name" value="antiport_nhaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="165"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="515" mass="54593" checksum="3958BAE1626A9DAD" modified="2014-06-11" version="1">MEQVKEPKIPSLGLSILVFLAVAVMIAAAVLVWETDIHIVLIFGALLAGLVGVFYLGNPYSKIEKGIIDGIMVGMQACLILYTVGPLVGTWICSGVVPSMIYYGLSILSPSIFLLATLIICSIVSLATGTSWGTAGTVGIALLGIALGLGVPAPLTVGIIISGGYFGDKMSPLSDTTNLAPGVAGTDLFQHIRAMCWTSGPTYAIVVCITLFLGFQYSQGDLDYTKIEALKTILASEFWISPISLIAPLAVIVLSAMRKPALPALWVGVFIAVVFALVQGTNFGDILNIMQNGYVPMLSAEIAGTGEDAAALAKILADNSISLDPKIALEAANDIVSLMERGGLQSMNWTISLILCAFTFGSTMDVCGFLKVMLQAIMKPIKSVGGMITAVILSCFVCDIFLGDQYLAIAMPGTMFKSEFDKSGLHPRMLSRSLEDAGTLLSVLVPWNTCGAYHAGVLGVPTFEYLPYAFFNYLNPIVAIVMTFMGIGIFWRGKNGEPVKGGKTRPAELGPKVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9L1</accession>
    <name>A0A011A9L1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442065.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022426_4_1_0"/>
    <dbReference type="OrthoDB" id="995276at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="215"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="596" mass="68126" checksum="553C4E8E5F289DA1" modified="2014-06-11" version="1">MIRKDSRVYKSGAVKTQVRVVEGYRPGPGCPPKQRTLKNFGYLEDQEDPVAFMAMVREYDENCKNEPVTRLEVPSTLKMYSLSNRVRNYGCRFLEALYNSLEIDGFIERYAAYSGYKGNIPLAEIFKFFVLTRILAPDSKRGSCQMKEEFYGLSCDFSLQDAYRALDVFGDMSQDLQLWLNNEVKRSIGRDMSYAFYDVTNFFFDIDFPDDEGGYRRRGVSKEHRVDPIIQMGLFLDEKGLPACMSLFPGNRSDCMTLKPVMAEVRGNYGLKRLVVVADKGLNTSKNIDMICNNGDGYVVSQVLRGKKGSRYHEAMFDDGGYIQNADGSYRYKLFTEEYTGKDNDGHSVERCRKVLIYWSRADAEMARRKRVEKLLRAENATKNNAYSIQHGCLEYTKEEIRDGHDGHIVKNVRKRLKLDEEKAEADSRFDGYFCIITSEMEYDASKIREVYGGLWRIEQSFRVMKSGLEARPVFVSTQKHILAHFTICFTALLIVRLLQLKMGEDAISAERIAAALGAANCQVLRGGIVHLLDVGGSMAFKKRIGRNGKQVDTLAFSCEDEIALDYAKIQKAFCVDFYDAYPKQEVFNRFLKGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9M4</accession>
    <name>A0A011A9M4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid/amide ABC transporter substrate-binding protein, HAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710812.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.906"/>
    <dbReference type="HOGENOM" id="CLU_027128_6_1_0"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458324" evidence="3">
        <location>
            <begin position="20"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="22"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="379" mass="41723" checksum="866AE1281C601668" modified="2014-06-11" version="1">MRKLFAVLAIMLLALPAFAADTIKIGEIATVTGDFAAYGVAEVESVKMAVSEINAKGGVLGKKLEVVMYDCRTRNEDMVNAARRLVQQDKVVAVIGPSGSGLCIAASPVFNQGKVAHIGTLPTNPNVTVDEKGKVKPYNFRICFLDPYQGKILAVFAAKDLKAKKAAILYDVSSDYSHGLREFFTKSFKAAGGTIVADEGHRGEDVDFRAQLTKIKQSNPDVLVLPTMGKCTPLSVKQAREMGISVPIIGGDGYGDFMWEITGKEAMRNTFWVSHVAKEDPALKDFFAKYKKQTATECQEFMNAVMAYDSVYWLADAIKRANSTDPVKVRDALEKTKNLQLMHTKLTMDEFHNPKDKDGFILEAKDGKAVFYKKIRPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9U5</accession>
    <name>A0A011A9U5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type sugar transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710906.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.968"/>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_0"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="274"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="536" mass="59078" checksum="B656F519DC19E1CB" modified="2014-06-11" version="1">MSMEIPLLKMENIGKEYFGNRVLQDVTFSLRPGEIMGLVGENGAGKSTLMNILFGMPVIQETGGYEGKIMIDGQEVRFKDPLDALEAGIGMVHQEFSLIPGFTATENILLNRESVKYNALVEVFGERLMTLDRPEMRERAEKAIKTLGVELSPETLISEMPVGHKQFTEIAREIDRSKTRLLVLDEPTAVLAESEATVLISALKTLSKQGIAIIFISHRLQEIIDLCDKLIVLRDGRVIQEACTKETNVRQIAAWMVDRKGDKAGEEKAEKKEKTIGDVILRTEHLWVDMPGETVRDVSIEVRQGEILGFGGLAGQGKVGISNGIMGLYAAGGKVFLRGKEIKLNDPDASLKEGMAFVSEDRRGVGLLLEEGIDWNITFTAMQVQEKFIRKLAGGLVKWRDDKAIEECTREYIKSLEIRCTGPAQRAIELSGGNQQKVCLAKAFAVSPEILFVSEPTRGIDVGAKKLVLDTLRRVNEEDGTTIIMTSSELEELRSICDRIVIINEGRVSGILPASAPAEEFGLLMLGHVEEPAAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCM1</accession>
    <name>A0A010YCM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cobalt-precorrin 4 C11-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709856.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.103"/>
    <dbReference type="HOGENOM" id="CLU_011276_7_1_0"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046026">
        <property type="term" value="F:precorrin-4 C11-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11641">
        <property type="entry name" value="Precorrin-4_C11-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006362">
        <property type="entry name" value="Cbl_synth_CobM/CibF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01465">
        <property type="entry name" value="cobM_cbiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG77990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="251" mass="27284" checksum="1D5B5AE9258E7422" modified="2014-06-11" version="1">MIHFVGAGPGAPDLITLRGARLIEEAGMIIYAGSLVNPELLKRAKEGCEIRDSASMTLDEVIEKLREAHEAGVDAVRLHTGDPSIYGAIREQMDRLKELGIPYDITPGVSSFCAAAAAAEAEYTLPSVSQTVIITRMEGRTPVPEKEKIRLLASHRASMVLFLSTGLLDGLCAELIMGGYPPETKTVMVYKASWPEQRVIRATLATLPLLAADSGIKNTALILVGDFLGDEYELSKLYDKHFSHGFRRASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCS2</accession>
    <name>A0A010YCS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709231.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_1_0"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="73"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="277" mass="31224" checksum="5CB05D78E84FEA3D" modified="2014-06-11" version="1">MSEKQLETGTQAIQRALAILNCFTRGIDDLSLTEISKLVQIPYSTASRIAGILEQESFLIRDKSTKRFSLGRRVYSLGYCAKQNDFLRKVTYPYLVRLRDEFGETALVYIREGDYRICFEKVPAFHSFKFSPTVGSKYVLWAGAGGRGFLAYATPEEQDSFLKDTRNLTTFTTTDRAKLMRELYNLCKNGYSYCINEYQEGFSSIAGPIVGNDGNILCTIAVTGPSARFTDNIVKGLKERIPQYCAEISSTFGWSEPAENPDFLFRSPSLDHIIGNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCX5</accession>
    <name>A0A010YCX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-methylhydantoinase A/acetone carboxylase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484783.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014140_2_0_0"/>
    <dbReference type="OrthoDB" id="327092at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="195"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="545" mass="57412" checksum="BCDCA5D8BFB9084D" modified="2014-06-11" version="1">MRKGQEARLKRLTIGIDVGGTNTDGVLYDTETRSILSSVKTSTDHADYRSSIETAVGRLLQSASPGEIISLNISTTLSTNALLEGKGAPVALALIGYEDFPHIKDEILREVSPAALLSARGGHNGWGKERQALDREALLRFAKENSGGYFAVSSLYSPRNPLHEMEAAGIIKAAGCAGVTCGHEMARSKLNSVKRTVTAFLNSSLMDVTERLIGGVEFCAASHGLRCPVMFLRSDSSLVCGQWCARFPLETVFSGPAASMRGAMLLGGVKNEDAVIADMGGTSTDIGVVRNGKALYSKEGAAIGNYRTMIPSLEINSIALGGDSSVKIGEDGRLAIGPERVQPYCRASAGEECGYTPTDALASLGIAGVGSSGRSLRASNEYGERLGLSAIEFARLVRKEVSERLREALAQSGKEARRICVGAPIAAFAGGDNCSVPDDAAIASAAGAASSSLSLDCTVSILHNFFDGNFYAFLPVSQIKGSDLESVLSRSRAALEKYLTEQAALMGFKDVSAGISEEYEYIGREKCLSSLAAITLSGKVIVHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YD90</accession>
    <name>A0A010YD90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative efflux protein, MATE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441460.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.315"/>
    <dbReference type="HOGENOM" id="CLU_012893_0_1_0"/>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="449" mass="48464" checksum="AC10163E7BC829F9" modified="2014-06-11" version="1">MEEENIFGSLPMGKLITKMSVPVIATMLFQALYNVVDSLFVARLGLNPLTALGLAYPIQIIMISAANGIGVGMNSVVSRRMGADDTTGAGKATGNAITLGIICSVLMLLFGLFGAKPFFSISTNDTEIMGYGVQYLSICCIYNFGLFFSIIGQRMLQAAGQPAWSMGVHLIGCIFNVIFDPIMIFGWFGFPAMGVSGAATATVGGQILSAVAAFVVCAIKKKSVAFGLKDLCPSKDIWKMCKVGAPAAAAMGIASVMSFGMNQILKTEAIGLAVFTVFYKLWCFVIMPINGLLQGVVPVMGYNYGAKKRERVASAIKLTILAGVVIMFIITILFQMFTGQFISLFDNGKNGADFMPAGIHALRIISWVFIPFGFGQVGSSLFQGMGKGTPSLIYALLHQCILLLPPAWLFLRWGGVDLVWYSFWVAEILSAAITAFVFRYQYRKIMAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDJ3</accession>
    <name>A0A010YDJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative xylanase/chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_6_1_0"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="92"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="294" mass="33569" checksum="FB745FB8E68F2DB4" modified="2014-06-11" version="1">MRYFGSVAFFRHLIILALLLMAVLSGKYLIDVFIRKEPSEIKKERVSDLQYDKKSLSESNGTPQNRPPSFSYQSAYSELYGAAGQERALQDGVVYLTFDDGPSKYTPAFLDLLKKHGVQATFFLVGINVQRYPSVARRIKSEGHAIGVHTYSHKYLQIYMNVDSYLKDFSMAEDAIYRATGDRCAIFRFPGGSINVFNSRIYGELTAEMLRRGFKFYDWNVSAGDAVKKTIKKNIIDNVANNVRRDQPNIVLMHDTSELSLASLEQIILRLKKENYIFKALGSEDRPITFTHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDX0</accession>
    <name>A0A010YDX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1021977_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="272" mass="29763" checksum="7646C4EE339762B6" modified="2014-06-11" version="1">MKDGKSGMYPVFRPRRFWTSVLWLVFLAAGSAFSCVFGIFAFFTAVLVSVFIGLNEFGRWSYKTNLVICAGTSVVVAVAGVFTWMEIASLFVLFFAVSAYLLYFRDRASRLIPSLEAFAASLAKAPDFDSIIESAWRGIQEMAPEAAVFIVLADIEGCLYVPDHFDVPGRALKRNGGTPWKVFASGRPMNVIRVSTGRDQPLDRDALSLISVPITARGEKLGVLQLEAGTAGAFSEEDVAKLSLAAMIIGHELYMFESSEAVVREADEDDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDX9</accession>
    <name>A0A010YDX9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplM</name>
        <name evidence="5" type="ORF">Cloev_0529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441769.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.566"/>
    <dbReference type="HOGENOM" id="CLU_082184_2_2_0"/>
    <dbReference type="OrthoDB" id="1822215at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="144" mass="16161" checksum="8AFABAA659AEEA60" modified="2014-06-11" version="1">MIGTRSFMAKGEEVEHKWYIIDAENKPLGRLAVQVARILSGKHKPTYTPHVDTGDFVVVINAEKVGLTGNKLTQSTISKHSGHPGGLKVLTYKQILERRPERLVERVVWGMLPKTKLGRDMYRKLKVYAGAAHPHAAQKPEQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE31</accession>
    <name>A0A010YE31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Looped-hinge helix DNA binding domain, AbrB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441835.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158484_9_3_0"/>
    <dbReference type="OrthoDB" id="1942483at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="79" mass="8827" checksum="7707CDC1ADBAA426" modified="2014-06-11" version="1">MAELTTVSHKGQITIPKAFRDEFDIQPGDRVFFVKTEKGIMITKPKKTLLEYKGFLVGAKVESPDDAAKEFAEHIMGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEC7</accession>
    <name>A0A010YEC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484861.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.744"/>
    <dbReference type="HOGENOM" id="CLU_069356_12_7_0"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="205" mass="23989" checksum="224B0F0311F3CCD2" modified="2014-06-11" version="1">MYIRSNKRKLQAIETKNRIFDIAHTMFRERGFYNVTVEEIADAANISVGALYHHFKNKYELLTAWHDRLDEQYAKYYINIKNDPHFANATAPEIIKEMLLYIQETCINYGTEYISVIYSYLLSNTEFATIMTDMGREYYKIMTELMEKGQDEGTIRKDIPVAQLVHDLTIVSRGCLTDWAIEHSNKRMRDFSKSVLDSFLRGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEF1</accession>
    <name>A0A010YEF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710599.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_19_8_0"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="18757" checksum="261521573491F66A" modified="2014-06-11" version="1">MRIRPVTHRDAEGIDKINAKVAEGRLFNFSTGKFEDVGQLIAGLTQFDHMFVLETETEPQEICAVVLLQVNHQIFLRRMATLRIIVDPKWQGQGLGKALMASALDFADDELMMERVEVEIPTDNVNALKLCKSAGFKVEGIAKDWMRSHEGHFVDAYLMAHCRNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEG2</accession>
    <name>A0A010YEG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative amino acid racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441968.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067103_0_0_0"/>
    <dbReference type="OrthoDB" id="859043at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="362" mass="39100" checksum="67919884DABBC2A2" modified="2014-06-11" version="1">MPLEQKKTKYPLLRVKLDNIRKNAGSLVAECARHGVNLWGVSKGISAFPEVARAFASGGIKIIADSRLDNIRRMREAGVALEYALIRIPMRSELEELAELCDYTLISDIGTLEALAEICEKSGREVKCVVMFDMGDLREGFWFKEAERTAAGLAKFTGKMKIAGVGANFACASGVLPSARNLTELAACGAAVEAALGRPLAIYSGGGTGSFVMMRRGSLPGAFNNLRLGEALLLGRDTSFGMLLDGLSQDTMRIEAELVEVRTKPTLPVGEIGHDAFGSVPVFEDRGDRRRGILALGKQDVNISGLEPLDDGVRIITASSDHLLVDIEERPDLKVGDVLSFRPDYTAMLSSSTSPYVTKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEK4</accession>
    <name>A0A010YEK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ethanolamine utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442018.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.815"/>
    <dbReference type="HOGENOM" id="CLU_143326_0_0_0"/>
    <dbReference type="OrthoDB" id="1891661at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07046">
        <property type="entry name" value="BMC_PduU-EutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044870">
        <property type="entry name" value="BMC_CP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009307">
        <property type="entry name" value="EutS/PduU/CutR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40449">
        <property type="entry name" value="PTHR40449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012296">
        <property type="entry name" value="EutS_PduU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51931">
        <property type="entry name" value="BMC_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC circularly permuted" evidence="2">
        <location>
            <begin position="10"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="117" mass="12472" checksum="50CD273796B0ED24" modified="2014-06-11" version="1">MTGEFENKQRIIQEFVPGKQVTLAHVIAHPVADLYGKLGLFETEGAIGIFTITPSEGAMIAADIASKAANISIGYVDRFNGSLLITGDVAAVEAAMRDVMSVLCDLMAFTPARITRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEN6</accession>
    <name>A0A010YEN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl-CoA mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710719.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.849"/>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_0"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="1">
        <location>
            <begin position="37"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="559" mass="61522" checksum="C7BD0D8FC18C4FAF" modified="2014-06-11" version="1">MFEPTQLQEVAEGKKAYEAAVAKALAKGPERKENFTTSGGIPLKRTYTPEDVNGVDYAKDLGFPGAYPYTRGVQPTMYRGRFWTMRQYAGFATAEDSNKRYRYLLSQGTTGLSVAFDLPTQIGYDSDDPMAVGECGKVGVAVDSLADAEILFGGIPLDKVSTSMTINAPASVLLSMYIAVAEKQGVPMNALSGTIQNDILKEYIARGTYIFPPKPSMRLITDIFDFCSRNIPKWNTISISGYHIREAGSTAIQEVAFTLADGIAYIEAAIKAGQDPNVFGKRLSFFFNAHNDFIEEVAKFRAARKVWARIMKERFGVTEKGAQMLRFHTQTAGCTLTAQQAENNIVRVAVQTMAAVCGGTQSLHTNSLDEALALPTDKSVRIALRTQQIVAYESGVTNIVDPLAGSYAIESLTKEIEEGAWEYIKKIDELGGMMTAIEKGYPQKNIQDSAYQYQKSIESGDRIIVGVNKFHIEEDMSERKLLKVDASVGVNQIKKLREMKENRDNVKVKSTLDAIRDGAKGDANLMPLILDAVHAYATEGEICGVLREVFGEYQENVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEP2</accession>
    <name>A0A010YEP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biotin carboxyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710731.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.854"/>
    <dbReference type="HOGENOM" id="CLU_016733_5_2_0"/>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="49"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="130" mass="12690" checksum="8BB45443C4614C8E" modified="2014-06-11" version="1">MSRKYRVTVNGKAYDVDVEEMGAGAAPAPVAAPAPVAAPAPVAAPAPAPAAAPAPAVPAGAGSITAPMPGKVLKILVAQGAAVTAGQLVIILEAMKMENEIFTTVAGSVSQICCKEGDTVSTGDTLLVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YEV0</accession>
    <name>A0A010YEV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyrroline-5-carboxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484878.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066353_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="2">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="272" mass="29617" checksum="E4D111F4E005E5DB" modified="2014-06-11" version="1">MAVDLTLGFIGTGGITSFLVRGLCSAPEFTGRVILSVHKNRGKAEELKELFPERITICESNQEVADSSDVVFIAVLPQQHEAVAGAVKFKPEHRVVHITGGVKLEDSRSLYAPAARAVRAIPLPFAAMRMGPVLFYGDDPVCRELLAMLGSIVEVRAESELEVLGPVTGMMVPYYALIAEYVKWGTAKGLLFKTALDYAGYMNEALSSFMRTHCTEDVETFLIDNSTPGGVNELGLKLLREGDAYSSWSKTLDALYVRYNSMGKNGVAGDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF22</accession>
    <name>A0A010YF22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484894.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1381642_0_0_0"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="188" mass="21603" checksum="2E5C167A3959D188" modified="2014-06-11" version="1">MSKTNDTPPIDKYNALFATSLRAFMDAHPDTGEKTTQKALADYLGVRPQTVSYYCTGESLPNCEQLLRIADFFGVTCDFLMTGRRIENKPVRELLGLSENTVQNMKLVKEGYFEDSPYMLAALDTLLGDKDFYLSMEQAANWYGQKEQAPDDMKEFCEWKAAQYMQGFLLEFFARNLRAIYEQMRGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF64</accession>
    <name>A0A010YF64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplX</name>
        <name evidence="6" type="ORF">Cloev_0990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710999.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1060"/>
    <dbReference type="HOGENOM" id="CLU_093315_2_0_0"/>
    <dbReference type="OrthoDB" id="2040741at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="108" mass="11871" checksum="170D05CFA3DC99C7" modified="2014-06-11" version="1">MSKMRIKKGDRVRVISGKDAGKEGKILKRNIDKDTVVVENVNFVTKSVRPTQKDPRGGLVKKEAALSASKVMLVCPKCGKATRVSRAFLDDGKKVRICKQCGEIIDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFH0</accession>
    <name>A0A010YFH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-layer domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442448.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041895_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457580" evidence="1">
        <location>
            <begin position="23"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="509" mass="57159" checksum="ABD88695743B9500" modified="2014-06-11" version="1">MKKILAVIAMIASMAMAVPAMAATNPFMDVPQGHWAYDAVGLLASRGIVSGYPDGAFKGAQPATRYEMASVVARALVAVDADKASKQDLELLKKLVMEFKDELDALGVKVDKLDKRVAVLEDGVGGWKIRGTFMFDAKFANDTDNGQYYYNESNKKNDFEKEQFRLYLTKQIDENTYFYAEYRTGADDAGDDVNGRGDLQHMMWSHLFLDTKLPYDIGFRVGRFTVDFEEEYGLYTDNDAVFGDFRTDGFRLTKQWSNFRATAVVGRNDNLGIDGMNDSGSGTHMTYVLDLNWQPGEKFFAGATGYWFDDDSTPDTAGDLGVKNYGLYAGYKFTPAVELKGIYYFQDLGKDVSGAAYEDSPKAWKAVLDVKQDLLKFTGLWIEYSQQDNTFLGYNDRYSIGGGAYDHVGRNMEYANPYGTSKWWFVKADQQWNDKWSTFIRFANVGYDTAGLDDATEWGLGVGYQYTPAIGFELAYDQVDHGDNGWAVGDPEVARGKDHVVRFRTTINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS32</accession>
    <name>A0A010YS32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhageMetallopep domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708512.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1626272_0_0_0"/>
    <dbReference type="OrthoDB" id="1514574at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043998">
        <property type="entry name" value="Put_Metallopep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18894">
        <property type="entry name" value="PhageMetallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhageMetallopep" evidence="1">
        <location>
            <begin position="13"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="19441" checksum="72887C5BDF91F8BF" modified="2014-06-11" version="1">MSVKTDAEFDYEICSSKIRPIAEALIKKYDELHHIDPDKILFVVNHKSAGSKKQMTLAKTTRISPKWTELIYQLGSCSYFYMIEFYAKTTATMDESQMVALVYRELRRIGPEGEILTPDVHDWWQILMGLGRKWFYPDSTCPNLLDDNVDWKKLMGTYYEEIHQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS61</accession>
    <name>A0A010YS61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.57"/>
    <dbReference type="HOGENOM" id="CLU_025908_1_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="33"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="300" mass="33421" checksum="91FCE553B13877CD" modified="2014-06-11" version="1">MRDMNTIAALDIGSNAVRFLICNIEESCDAKKCRKVAFLRVPVRLGEDVFTEGRISSRRRALLCEAMQGFAHLMKTFDVKDYRACATSAMREAKNGGEVLEEIREKSGISVEVISGLEEAEIIYAAGVPTAGGENWKDSLHIDVGGGSTEIVVYAGGRVAESHSFRLGTVRMLKNAVKEEEKELFKSELRKIGDKYQNLRMIGSGGNINKAQKLLNKRVGEPLNFVELRMLYDTLKKMTFEERIKNFKLNPYRADVIIPALKIFLTVSKLCRAPTIIVPQVGLVDGIISILHAKQSVKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS94</accession>
    <name>A0A010YS94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin isomerase</fullName>
            <ecNumber evidence="6">5.4.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0092</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobH/CbiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.1.2" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441279.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.106"/>
    <dbReference type="HOGENOM" id="CLU_084703_1_1_0"/>
    <dbReference type="OrthoDB" id="1812068at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016993">
        <property type="term" value="F:precorrin-8X methylmutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003722">
        <property type="entry name" value="Cbl_synth_CobH/CbiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036588">
        <property type="entry name" value="CobH/CbiC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02570">
        <property type="entry name" value="CbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63965">
        <property type="entry name" value="SSF63965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiC" evidence="5">
        <location>
            <begin position="5"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG77993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="202" mass="21222" checksum="35A011632540B42E" modified="2014-06-11" version="1">MRPNEIETASMNIIASEMGAWLGAPEELPVVRRVIHTTADFDFAENMRFSKGAVKLAREALKNGAAVVTDTNMAAAGINRAACARFGVEVVCRMADPAVREAAEARGTTRAVVSMEEAVKATPNALFAVGNAPTALIRLCELIEEGKCAPALVIGVPVGFVNVVESKERLLAAKVPYITAVGRKGGSPVASTIVNALLYGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSA2</accession>
    <name>A0A010YSA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative TIM-barrel fold metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709870.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_0_1_0"/>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="264" mass="29817" checksum="9B4A358004C5993C" modified="2014-06-11" version="1">MIIDFHTHVFPHKIADAAMTKLQHQCGVPYYAPATAESLVKTMDACGVDKSVVLNIVTKETQHEDVLSFAKEIDSERLISFGSVMPGSEYALEYVWKISDEGLKGMKLHPPLQRIDVDDKRLFPVYDLARALNLVVIFHAGWDATYRDEMRASVEMTINVVNNFPGLKLVAAHMGGLRIARDVFDRLAGKYELYFDTAYAADPWLDKGMFRDIIRRHGAEHILLGSDYPWHLPSMEIDLIKSLDIGEEEKKMILGENAARLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSM6</accession>
    <name>A0A010YSM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[Citrate [pro-3S]-lyase] ligase</fullName>
            <ecNumber evidence="1">6.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetate + ATP + holo-[citrate lyase ACP] = acetyl-[citrate lyase ACP] + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23788"/>
            <dbReference type="Rhea" id="RHEA-COMP:10158"/>
            <dbReference type="Rhea" id="RHEA-COMP:13710"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82683"/>
            <dbReference type="ChEBI" id="CHEBI:137976"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.22" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709398.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.259"/>
    <dbReference type="HOGENOM" id="CLU_063190_0_0_0"/>
    <dbReference type="OrthoDB" id="1354563at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008771">
        <property type="term" value="F:[citrate (pro-3S)-lyase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005216">
        <property type="entry name" value="Citrate_lyase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013166">
        <property type="entry name" value="Citrate_lyase_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40599">
        <property type="entry name" value="PTHR40599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08218">
        <property type="entry name" value="Citrate_ly_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005751">
        <property type="entry name" value="Acet_citr_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00764">
        <property type="entry name" value="Citrate_ly_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00124">
        <property type="entry name" value="cit_ly_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="346" mass="37193" checksum="330844AB12728A0A" modified="2014-06-11" version="1">MFGFNCRVTRKLCGYERRAVEGLLERSGLVFEGSPDYTAVAEDCDENIVATASLSGSVIKMVAADPRWQEAGLSGAVISALMRAAREDGLYHLFVYTKPEMAERFAGLGFRELAASSRSVLMECGAPGVEDYRRSLEALRRENGAPAAAAVMNCNPFTLGHRYLIEEAAKRSPLFYVIVVEEDASVFPFADRLELVRGGTADIANVRVISSSHYAVSAATFPTYFLKDRGESSVARAQAELDARLFASLFAPSLGLERRFVGTEPLSFVTALYNSVLKETLPGLGCEVTEISRAASGGEVISASRVRAMIAAGEEAGLAALLPAVTLEYLKTPRGAAVAAKLRDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSR2</accession>
    <name>A0A010YSR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tripartite ATP-independent periplasmic transporter solute receptor, DctP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.299"/>
    <dbReference type="HOGENOM" id="CLU_036176_1_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004682">
        <property type="entry name" value="TRAP_DctP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006470">
        <property type="entry name" value="DctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00787">
        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001457679" evidence="2">
        <location>
            <begin position="21"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="326" mass="36102" checksum="34420F93C799D17E" modified="2014-06-11" version="1">MMKKLALVLSFALAATALFAASGFAATTIKIGHVLNTDHSWHKNLAGFANDVKKETEGRVTIQLYPSGQLGNEKDMVEGLTFGTVDGGLIGGGSFQSIDPKFGIEALPYAWPTHEAAYKAFDGKLGKYLFDLLGKKGIVGLAWWENGFRHITNNKKPVVKPEDLKGLKLRVTPDKMRLDTFKLLGAAPMAINFGELYSALQQGVVDGQENPYAIIYSNAFNEVQKYLSKSGHIWGSAVLCVNSDVWNKLSAKDKETVRKLAQKWCAAQRKETIKEENEFLDKLKAKGMKVNDVDKAAFQKAVQPVWKSYESTFGKELMDMVHEYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YST2</accession>
    <name>A0A010YST2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441471.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.323"/>
    <dbReference type="HOGENOM" id="CLU_050659_1_1_0"/>
    <dbReference type="OrthoDB" id="1497065at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041380">
        <property type="entry name" value="Acetyltransf_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025559">
        <property type="entry name" value="Eis_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17668">
        <property type="entry name" value="Acetyltransf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13530">
        <property type="entry name" value="SCP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="397" mass="46229" checksum="227CC9129C69C435" modified="2014-06-11" version="1">MSIDIRKLTAQDLDQYNGLLRYAFQVTEKTLLESGWEDEDIKQSKFPVLERASVWGCFDGDELVSQFAVYPLEMNIHSVVYQVAFITSVSTYPEYSGLGLMSQLMKKGLSEMRDNRQSISLLYPYSIPLYRKKGWEIISDKMSYSIRDVQLPKNIEAAGYVRRVSWEDPDFMDLHTQFAKQTHGCLFRNNLAWDEYWKWDEDDTTVAVYYRDDDLPRGYMVYLIKDDIMYIKEMIYLDMESRKGLWKYIGAHESMVGEVRGYNYFSEPIAFSFEDSEIKETIRPYIMGRLVDTRMFLEKYRFRGEANGGVTLRISDPFLEWNDQSLTLDIAGGRCEVTKTASRHTAAMSIGTLTTLLLGYKRASELAALERIDADRETIKFLDNAVIHKKPYISDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSW5</accession>
    <name>A0A010YSW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative low-complexity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441517.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033401_5_0_0"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13576">
        <property type="entry name" value="Pentapeptide_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="200" mass="22078" checksum="265F58C68974BF74" modified="2014-06-11" version="1">MLSEIIYAAFSGEMLIEDAVFENEMVSALDLSGFRFDSVRFVKCRFDGCEFNAARFNSVSFENSDISNCRFKESLWRKSVFLDSKAVGSCFIRALFRDAAITGCDFRYANLDGMLWDGCEVRASSFKEAVLSGVKFRRALFHETDLSAADFFKSSLKGIDLSDCSIDAIAVSDTLAELRGAKVNAAQAVELAKLIGLSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT59</accession>
    <name>A0A010YT59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn finger protein, B-box type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3060156_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B box-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="53" mass="6217" checksum="2AC614CA2B5303AF" modified="2014-06-11" version="1">MSSETLRTTDGKEYGECTECGKSGRVYWCFFCDEGPLCWDCLEEHKSDYHNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTA3</accession>
    <name>A0A010YTA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709624.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2021866_0_0_0"/>
    <dbReference type="OrthoDB" id="1817042at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="122" mass="13289" checksum="0E4A5FF9765071DE" modified="2014-06-11" version="1">MNLDIKNLEDQDMKQLVKSLELVSARIFDSVVRVSQLAASNTPEMQQLFSQWVDCLGDAIISAVEKEGGLYPDELAQNIGVTPATIISLALTLHREGRIKITEIKAEPASGDNTEICGCMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTD2</accession>
    <name>A0A010YTD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ornithine cyclodeaminase, mu-crystallin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441799.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.588"/>
    <dbReference type="HOGENOM" id="CLU_042088_3_1_0"/>
    <dbReference type="OrthoDB" id="1193876at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="PTHR13812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="335" mass="36882" checksum="EC67C79A721F4C0B" modified="2014-06-11" version="1">MPCKLVNAEIVEKLLTMKDAITACEEAFCDWGNGEVVCPTKITLELGEDAEWPPYKNGLNAMPAYIHSKKSAGIKCVGGSLNNPQWGLPYIIALILLFDPATGIFRCVMDGAQITNYRTGAQAAVAAKYIEDKKKIKFGLFGAGVQGRTQLMAFNEVFEIEEVHLYDINSQAAKAFVEEMSKTVNTKFVIKEDPKDVMDDTDIIVSVTHGRNKFIKNEWFKKGQIIFPMGSFTECEDELLLGADHVIVDSIGQTMHRGALKSVVDSGKFKKENISATIGELVCGKKEYHISPDEKIVCVPIGTGAMDVAVATMIYEKAMAQNFGEPYVFNNAVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTN2</accession>
    <name>A0A010YTN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710421.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.705"/>
    <dbReference type="HOGENOM" id="CLU_021802_2_2_0"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010182">
        <property type="entry name" value="ArgE/DapE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01910">
        <property type="entry name" value="DapE-ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="197"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="407" mass="44920" checksum="937D7994C7E60656" modified="2014-06-11" version="1">MNKELLAKIESLETRMVETLGEMVSYPAISPLDGGEGEFHKAQYLLKKIKELGFEDVKVYASTDPEAAGGERPNIVIRFPGKTKRRLWIVAHTDVVPEGERSLWETDPFTAVVKDGRIYGRGVNDNGQEVVASLYALYAVKELDLTPEYEVCLAFVADEEVGSTHGIKYLIKKGLFDKDDLVVVPDMGTEEADFVEIAEKSICWMEFTVEGKQVHASLPNLGINACRAANGFSVSLDEALHAAFPETDELFDPAGSTFEPTRRRANVANINTVPGVESLCFDCRVLPTAPLEDVRKVVEAEIKKAQEKYGVKITYRFPQYEEAPEPTRADAPVVTELLAAVKEVFPKVTPKVGGVGGGTCGAYFRREGIPAVVWGQESDCAHMPNEYTKIEHLLNEAKVFALMMLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTV1</accession>
    <name>A0A010YTV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052868_1_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0711">Selenium</keyword>
    <keyword evidence="2" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="60"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="253" mass="27525" checksum="9DDEBF934E348D90" modified="2014-06-11" version="1">MPDIRESIKQAYTEAVSRGGEETLSISDMTKDNYDEETLRDLPVQTFGCGNPIEAALLKPGERVLDLGSGAGLDLLLAAKRVGTEGHVYGLDMTKAMLDKARKNIDRLGFRNITLLRGYIEDIPLHDGGVDVLISNCVINLSPDKDRVFGEAFRVLSSRGRFCVSDVVLMKRVPEKLKKSPAAWSGUVAGALPAEEYAEKLKKAGFTQVSVTITKPHEINIEVVKSSVMDLTADDMRDIEGVSASALITAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU53</accession>
    <name>A0A010YU53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0816</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442044.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.868"/>
    <dbReference type="HOGENOM" id="CLU_036879_1_2_0"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="94"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="305" mass="33693" checksum="013F80C0522A9176" modified="2014-06-11" version="1">MLKYTLRRIISAVITIWFVITITFLIMHNLPGSPFTSARGLPDETRAALEAKYGLDKPLGVQYLTYLLNFVKGDFGVSYHKRGVTTRAIIESGFPYSAKIGLLAVAFILAFGIFFGVYAALRHNRMSDRVSMLLATLGTTIPSFVVATLYLYVFNKKLGLVPSYGAENFKDYIGPAFAIGAFSIAFITRLTRTSMLEVLQQDYIRTAKAKGLTSFVVMTRHALRNALIPVATYMGPCVASIVTGSFVVEKVFGIPGIGCLFTTSILNRDYSLILGVTVFYGVLLVLMVLLVDILYVLIDPRIKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUH4</accession>
    <name>A0A010YUH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442196.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062999_7_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028350">
        <property type="entry name" value="DNAC/ATP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003073">
        <property type="entry name" value="DNAC_TnpB_IstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="256" mass="29294" checksum="28B443C492A51ECA" modified="2014-06-11" version="1">MISQQTINQLHDMHLSFLAGDIKERQADASFCELSFDEQITVIVDREWHRRRSKRITDLIREGQFCYNSASVLEIDYAQERGLVKKQINELAACSYIENGHNIMIMGATGVGKSYLACALGTAACRNRYSCRYTRTPELLDQLAMARTDGSVRQIIQQYRKPRLLILDEWLITRISHGGLEDIFEIMECRSTEQRSTIFCSQIETSEWLAALGNSLMAESLMDRIIHCSYKIVLHGDSMRKKKGLKSIQASTVEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUI9</accession>
    <name>A0A010YUI9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sbcD</name>
        <name evidence="10" type="ORF">Cloev_0958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SbcD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442253.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1028"/>
    <dbReference type="HOGENOM" id="CLU_038045_0_1_0"/>
    <dbReference type="OrthoDB" id="1831911at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026843">
        <property type="entry name" value="SbcD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12320">
        <property type="entry name" value="SbcD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="8">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="SbcD_C" evidence="9">
        <location>
            <begin position="262"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="378" mass="42179" checksum="371E7DE8EA17D40E" modified="2014-06-11" version="1">MKFLHLSDLHLGKRVNEFSMLEDQEHILEEILAAAAAERPQAVLIAGDIYDKPVPPAEAVRLFDSFICRLSEAGIAALVISGNHDSPERLSFGSRVMARGGIYIAQAFQGTVQCVTLEDEYGPVNFYLLPFVKPAMAKPFFPEEVCGDTQSTVETILRDIHLDEGGRNVLTAHLFVTGCPRCDSEDVVVGGAEGVPAEIFNAFDYTALGHLHGPQTLPDGKARYCGTPLKYSFSESCQQKSLTVVELREKGSLTVHTLPLTPKRDLREICGGYNEIASKNFYDGLDTGDYFHITLTDEEDVFDAVARLRSIYPRIMRLDYDNSRTRSQTDVFTAARAESRTPLELFDELYFKQNGAELTEEQKRIVSSHIEDIWEDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUJ5</accession>
    <name>A0A010YUJ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mnmE</name>
        <name evidence="6" type="synonym">trmE</name>
        <name evidence="9" type="ORF">Cloev_0963</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442259.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1033"/>
    <dbReference type="HOGENOM" id="CLU_019624_4_1_0"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="8">
        <location>
            <begin position="219"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="229"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="248"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="273"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="453" mass="48044" checksum="8D62F9CBDE0C953D" modified="2014-06-11" version="1">MAEEIITALATAWGEGGIAIVRVSGEGCALLVDKMFRAKRRFSEQPARYMALGTLHAKDGTLFDEVLAVRFERGNSYTGEESAEIHCHGGALSAQRCVEELCALGARMALPGEFTRRAFVNGRIDLAQAEAVAGIIKARSDEALAASARSLQGSFTEQIRGLMDSLTELTAALEVDLDFPEEGEGFITDGESAERIKKLSGRCEELLSGCRSGMLLRDGVRAAIIGRPNVGKSSLLNALLAENRAIVTATPGTTRDSIEETFIYKGLPVRIIDTAGIRATEDEIEAIGVRRSLKSMAEADIILRVIDSSESAAEDEIGPLSAEKKQIVILNKNDLSTRTTEADVEALFPGCPRISISAADGTGVDELKELIVRTALSGGSVSGGCSVTARQVECLSRTKEAVEAAGEALLSDLGDDLVLSCLAEARGQLSSLLGLDASEELLDKIFGSFCVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUL2</accession>
    <name>A0A010YUL2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ORF">Cloev_0983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710988.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1053"/>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_0"/>
    <dbReference type="OrthoDB" id="1893906at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="94" mass="10509" checksum="5E57E3214DD6EF41" modified="2014-06-11" version="1">MARSLKKGPYVDVKLLRRVEDMNESGKKVVIKSWARACSITPEMVGHTIAVHNGRIHVPVYISDNMIGHKLGEFAPTRKFGGHAGQERSTKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUN0</accession>
    <name>A0A010YUN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infA</name>
        <name evidence="5" type="ORF">Cloev_1003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711020.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1072"/>
    <dbReference type="HOGENOM" id="CLU_151267_1_0_0"/>
    <dbReference type="OrthoDB" id="2066663at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="72" mass="8390" checksum="454E07CD1140322F" modified="2014-06-11" version="1">MAKEEVIEVKGKVVEPLPNAMFRVELENGHKILAHVSGKMRMHFIRILPGDRVLLQLSPYDLTRGRITYRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUS5</accession>
    <name>A0A010YUS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="10" type="ORF">Cloev_1067</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OMP decarboxylase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711165.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1135"/>
    <dbReference type="HOGENOM" id="CLU_067069_1_0_0"/>
    <dbReference type="OrthoDB" id="1150446at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01200_B">
        <property type="entry name" value="OMPdecase_type1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="PTHR32119:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="236" mass="25317" checksum="4D3D96F85F86D45C" modified="2014-06-11" version="1">MENNNCGLIVALDLPALDDARRFLDRLDKATKYVKVGPRLYALGGASFAKEIIGRGYELFLDLKLHDIPNTVASAVEPLSELGLWALTIHTSGGYEMMARSAAMRDKTGSRMKLLGITVLTSLGGELWSDVHPGCDMRQALIGRAETAQRAGLDGIVCSPLDLELLRGRAENLLRVVPGIRAKKVSTEDQTRVATAKDAAEAGASYIVVGRPILEAADPIAAAKDILKTLGEASHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUX2</accession>
    <name>A0A010YUX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N6-adenine-specific methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711236.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1189"/>
    <dbReference type="HOGENOM" id="CLU_075826_0_2_0"/>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="165" mass="18374" checksum="4CD953D6F636A7C7" modified="2014-06-11" version="1">MKEMRPTTGKVTLALFNILGNIHGRSFLDLFSGSGQIALTAARKGAAPVVSVESERKRHAEIVKKAPAGVKCLCFDVRRAVARFAKNGERFDIIFADPPYNLGWGEEFPKLMAANGEILAPNGVIIFEHSEEEEPAAMDEAEWEREDRRYGGTVLSFYSRRNNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGQ2</accession>
    <name>A0A010ZGQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Fe-S center protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708504.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.11"/>
    <dbReference type="HOGENOM" id="CLU_046240_0_0_0"/>
    <dbReference type="OrthoDB" id="1000643at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="370" mass="40031" checksum="5AE30CB54A68771E" modified="2014-06-11" version="1">MRSKVYFTNMRATPELNLLQKLAKLIKSAGIEEIDFKKQFAAIKIHLGEPGNIAYLRPNFSKVVADLVKELGGKPFLTDSNTLYVGRRKDALEHLDAAYENGYNPFCTGCQVIIADGLKGTDEALIPVEGGEYVKEAKIGRAIADADIVISLSHFKGHELTGFGGAIKNLGMGSGSRAGKMEMHSDGKPDIDEERCIGCGRCARNCAHKAISIKAGKAHNDHGKCVGCGRCIAACPFDAVQPDWEGSNDVLNKKMAEYAKAVIQGKPNFHICLVIDVSPFCDCHAENDAAVTPDIGFFASFDPVALDQACADAVNKAPAISGTYLTDKLHENGADADHFHAMHPDTKWRVMLEHAEKLGIGTRGYELIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGQ7</accession>
    <name>A0A010ZGQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2300884_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG77919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="100" mass="10270" checksum="5766B650AF5BA220" modified="2014-06-11" version="1">MMKVFFNKIKKITVIALTVTVVSAGSALAAPRGPWMQPNNPGQAAQRFYRAPQPKPAPHIAFAPAPAPRRHDGGSGDTAKALAVGAVIGAVIGSLAASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZGY8</accession>
    <name>A0A010ZGY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441282.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_935969_0_0_0"/>
    <dbReference type="OrthoDB" id="1998838at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038880">
        <property type="entry name" value="MJ0871-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38139">
        <property type="entry name" value="PTHR38139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="297" mass="31568" checksum="F97DBC23C258FC23" modified="2014-06-11" version="1">MDWRGLVAGELRLTFDILFGLLIGFAVLRSGLADRLMRRLVPHLRKAGIGSALGMALTLSLGSAKAGAAFIASALDSGDISERSAKWGTLLLSFPAYLHRWPSTMVMAASMAGASGAIFGAILLLRSAARFVLILFILKRGGEAEEAAEARQEGSARDIRFNKRLLKTLPVAWLFFAIAYMLVPWAESAIKEWLLAGTILPLAALTVAAASIAHVSAALALAGGSLAAGELTVAQAVFALLLGNSFGIITRLFRANAGYYFGLFRKETAQWLLFWNFATTAGFAVLSIALAALPLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH04</accession>
    <name>A0A010ZH04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441302.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.123"/>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_0"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="129"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="129"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="229" mass="25573" checksum="9F4DCE14168ABE1E" modified="2014-06-11" version="1">MKRRILIVEDDSQIRNFNCFAVENAGLEYAAAANGAEATGKLLSERIDLILLDLGLPDIDGMEIIKKVREWSEMPIIIVSARDQDKEKAAALDAGADDYLTKPFSATELSARIRVALRHLDRLGKPQQEAAKNVGGLRIELDRRLVYLDGGELHLTPMEYNLLALFFKNIGKVLTSAYIIRQIWGVGYGSDTQSLRALMASLRRKIEKSPAQPRYIVTEVGVGYRLVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH19</accession>
    <name>A0A010ZH19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0126</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.138"/>
    <dbReference type="HOGENOM" id="CLU_031026_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="268"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="394" mass="41801" checksum="FFF1322B07BF1655" modified="2014-06-11" version="1">MVSAARTPLGSIGGTLKNTQPEELLRVALEGAVSKAGIGKEIIDEVICGQAKQTTDAPNIARIVSLMMQIPEATPAYTVHRQCASGMQAILSGMQQIQCGYSDVVLTGGVESMSTAPFYIRNARFGVGNGNGVFVDPNIESQPKSQPNDIYGTFSMIQTADNVARQFGVSREAQDEFALASQTKAIAAIDSGRFKDEIVPVIIPQRKKEPTIFDTDEFPKRGTNMEKLSKLKTIFPEGFVTAGNASGRNDGAAAVMVASKEKVEELGLKPLARIIAGCAAGVDPRIMGMGPVAATRKLMKMIEPQNLKLDDFGLVELNEAFAAQSVACVNELGLNPETVNVNGGAIALGHPLGCSGARISTTLLYEMQKRDVRYGLATICIAGGLGMAMAFEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHF6</accession>
    <name>A0A010ZHF6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Citrate lyase holo-[acyl-carrier protein] synthase</fullName>
            <ecNumber evidence="2">2.7.7.61</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-[citrate lyase ACP] = diphosphate + holo-[citrate lyase ACP]</text>
            <dbReference type="Rhea" id="RHEA:16333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10157"/>
            <dbReference type="Rhea" id="RHEA-COMP:10158"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61378"/>
            <dbReference type="ChEBI" id="CHEBI:82683"/>
            <dbReference type="EC" id="2.7.7.61"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.61" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709400.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104529_1_0_0"/>
    <dbReference type="OrthoDB" id="1997330at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050519">
        <property type="term" value="F:holo-citrate lyase synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051191">
        <property type="term" value="P:prosthetic group biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005551">
        <property type="entry name" value="CitX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03802">
        <property type="entry name" value="CitX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="171" mass="19320" checksum="940C20184F6131EA" modified="2014-06-11" version="1">MTPLEEVLAGRDERAAWQRLWLEATEGSYFICQIGLNIPGYPKRIPRDIEIVRKCRKYLMDHAHAVPSEERYLENGAGVCWQGAFDALKFEAAALKKCAVEAENSMTAGRVLDIDIITREGSLSRTRMGFPERRCLLCGERAKVCARLGTHSQPELREKVIRIINAASLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHH9</accession>
    <name>A0A010ZHH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadE</name>
        <name evidence="9" type="ORF">Cloev_0261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441431.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.283"/>
    <dbReference type="HOGENOM" id="CLU_025662_0_0_0"/>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041856">
        <property type="entry name" value="NAD+_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="6"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="351"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="471"/>
            <end position="474"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="635" mass="69508" checksum="0AADD11B6B43A274" modified="2014-06-11" version="1">MRDGFIKVAAVSPEMRVADCDYNAEMIVDAAARAARDGVRLLVLPELCLTGYTCGDLFFQPTLTEAAERSLSKVMRAASDLSVVIIAGLPVAHGGKLYNCAAVIYRGALLGLVPKKNLPNYGEFYEKRWFSPAPEENATAWLCGEEVPFGSKLLFRCAGMRDFSFAAEICEDLWVPEPPSVRHALAGARIIANLSASDETVGKAEYRRALVLGQSARLVCAYVYADADRGESTTDMVFGGHDIVAENGRLLSECEPFTAGHSSAVTDAQLLAQERKRLTTYPEEGTAGYQTITFEMEASDTDLAERLIPRRPFVPDDGAERGRRAAAILTMQAHGLKKRLEHARAKKAVIGVSGGLDSCLALLVAVRASDLMKRPRTGVLAVTMPCFGTTARTKGNAELLCEALGVDFRCVDITEAVKLHFRDIGHKEDEYDVTFENAQARERTQVLMDIANKEGGLVVGTGDLSELALGWATYNGDQMSMYGVNASVPKTLVRHIVRYAADSAENEPLRRALLDILDTPVSPELLPAKDGEISQITEDLVGPYELHDFFLYHAVRCGFSPRKVRRLANAAFAGIYDGGTIDKWLKNFYRRFFAQQFKRSCMPDGPKVGSVTLSPRGDWRMPSDAAAALWLAELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHK9</accession>
    <name>A0A010ZHK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441459.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="146" mass="16225" checksum="FA381387C3B770D9" modified="2014-06-11" version="1">MLLPDKDIVAITKIYRKVNLWKNEQAAPLGLTAAQVPIVILACRKSGISQNEMVDELALEKSVVAKSIGKLMEAGYITRKQNKKDKRAFDLFPTEKAQAIYPILVQQGKNCMDLLTAGLSEDEKAALSDLLEKIVQNTYTQFLLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHV9</accession>
    <name>A0A010ZHV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RND family efflux transporter, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0386</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_1_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458164" evidence="3">
        <location>
            <begin position="27"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="70"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="109"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="379" mass="40119" checksum="F881925BB204D80A" modified="2014-06-11" version="1">MNRKKTIIIAALLLLAAACGALRLTAGGENGDEAGAESGPARVEAAKAEYGARIEEGFTTTSTLKALEEVEINAKVTARVKSIRVKRGDSVKAGQLLIELDSGEPAAEYDSQKAQLAVSKAEAEQSKAELEDANREYKRYGRLRKQGYATQQEYDSRATTLATAKADYERARASVSQARAQLAAKGVNLAEYRLCAPITGVVMEDYDLTPGTLVTSGTNAVRVARVDTLRAVVEIPEKDINGIGKGMTASVSCESAGGKSFTGRVSVINPYVDESTRTVTAEILVDNAAAGYILKPGMFANVRFVQKAEERPLLIPTEAIADDGTVMTVEDGKIKTVKIEKGASQNGKTSVKSGLAEGTLVVLSGGRNLKDSDPVETAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZHX1</accession>
    <name>A0A010ZHX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methylmalonyl-CoA mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709097.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.443"/>
    <dbReference type="HOGENOM" id="CLU_009523_3_1_0"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="6">
        <location>
            <begin position="597"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="731" mass="80304" checksum="3929D48F734A343A" modified="2014-06-11" version="1">MSSSNPDFTKIPLNMEPKRAVSYEEWKKKIEKETGKPFESLMHRTMEQIEVAPLYTKADYEGMSHLNYAAGLPPFLRGPYPTMYVTRPWTVRQYAGFSTAEESNAFYRRNLAAGQKGLSIAFDLATHRGYDSDHPRVVGDVGKAGVAVDSILDMEILFSGIPLGQMSVSMTMNGAVLPVLAFYIVAAEEQGVDKSVLSGTIQNDILKEFMVRNTYIYPPAPSMRIIGDIFAYTSHNMPKFNSISISGYHMQEAGATADIELGYTLADGLEYIRTGQAAGLGVDDFAPRLSFFWAIGKNYFMEVAKMRAGRMLWAKIVKQFGPKKAKSMALRTHSQTSGWSLTAQDPFNNVARTCVEAMAAALGHTQSLHTNALDEAIALPTDFSARIARNTQLYIQDETSVCKVIDPWGGSYYVEALTDELIRRAWAHIQEVESLGGMSKAIETGLPKMRIEEAAARRQARIDSGSEKIIGVNALQLEQEDPIDILEVDNSAVRDAQIARLAKLRANRNQEDVKKWLTAITNSVETGEGNLLELAVEAARARASLGEISDAVEKAAGRHKAVIRSISGIYSSEFAEEEIIEEVRKMTDEFEEREGRRPRIMVAKMGQDGHDRGAKVVATAYADMGFDVDIGPLFQTPEETAQDAIDNDVHIVGMSSLAAGHKTLLPQLVEELEKRGRGDIMVVAGGVIPAQDYQFLRDHGAAAIFGPGTVIPAAAKEMLVILNKRLAAAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI72</accession>
    <name>A0A010ZI72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cloev_0528</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709638.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.565"/>
    <dbReference type="HOGENOM" id="CLU_043773_0_0_0"/>
    <dbReference type="OrthoDB" id="241792at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="11">
        <location>
            <begin position="44"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="10">
        <location>
            <begin position="131"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="347" mass="37614" checksum="351458E1F890B574" modified="2014-06-11" version="1">MTVNPLDGQKDIASYEPVDGRLFSATHEEILTGWTTDIYFLKTRDVLRSAGLLETPVVAEVFTRKPGTFAGSEEVLNLFRKLPNPPRVEALSEGESFEAKEVVMRITGTYESFGLYETVLLGMLASSTGWATAAKECVEAAEGRNVLCFGARHVHPAIAPVMERAAKIAGCSAMSCILAAKLCGEEPKGTVPHAAILMVGDTVKLAKLYDAQVPAEEPRIVLVDTFKDEAEETMRVAEALGDKLSGIRLDTPGERGGVTPDLVREIRWRLDTAGYNKVQIIATGGLTPERIKVMNEAGADVYGVGSYITNGAQRDMTMDIKMVNGRPIAKRGRLPGIIPNPKLKRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIA3</accession>
    <name>A0A010ZIA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase, cyclopropane fatty acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441820.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.604"/>
    <dbReference type="HOGENOM" id="CLU_026434_6_0_0"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="371" mass="42500" checksum="A0E7D9887D425582" modified="2014-06-11" version="1">MLPLSIQQKLAVCGIEINGPHEWDPQVNNEEFYSRVIAEKNLGLGEAYMDGWWNCKRLDELLCRIIKCGVEYDIKGSLRYALLLLPMKLINMQSRSRSHRAAEEHYDIGNDFFFSFLDPLRQYSCAYFKDTADLDAAQVNKLELIAGKLELKEGDRLLDIGCGWGGLSKYMASRYGCRVTAVNISREQLAFAREDCKGLPVEFIECDYRDISGEYDKVVSVGMFEHVGSKNFRSYMNVVHRVLRKNGIFLLHTIGGNTSGINCDRWLNKYIFPHGSLPSAAQIASAAEGLFVIEDLHNLGAHYDKTLMSWYRNFTKSWPAFAERYGERFQRMWSYYLLSCAGAFRSRAIQLFQVLMTRSCDAREQPSATLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIB8</accession>
    <name>A0A010ZIB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0582</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441827.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1302796_0_0_0"/>
    <dbReference type="OrthoDB" id="1530824at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459059" evidence="7">
        <location>
            <begin position="25"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="30"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="212" mass="22801" checksum="1882A25FC002CD53" modified="2014-06-11" version="1">MKIMKTALTVLALLIISVPLPAEALISRAEAKRIWNKVAEPTALTALPFYIKDEETPNAWVTNGESVTVTTGLLNMLDTEAELYAVFAHEAGHVRLNHMHKSASRGAGLSIAAAILGQLLGGDLAGTAVNVGANLVNSGWSREQEIEADDYSVELAVKNGEDPVGMYSAISKLAKVNNTQPSGFNSHPPDDRRLLHIKNKILELKPGARFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIE5</accession>
    <name>A0A010ZIE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441860.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_521617_0_0_0"/>
    <dbReference type="OrthoDB" id="528536at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="519" mass="58885" checksum="418ACDC02737B09D" modified="2014-06-11" version="1">MLFSDKLEFLLDMTSTSNAQLARIINVDPSMISRLRKGRRGIPHDNSYIEAMADYFSKQLTKRYQLSALSEMLGCEELCHPVQPHLLRMILSEWLLSARYDEDNKARPLLKTFDRLPLYHDKNGADNTAAGDVKWNNSKLFVYYGNEGKRRAVCDFLQKILRYGTNCTIQVSSDESSEWIVENDDFAAKLSRMITALREKGCRCQRIAASASDINYSFDSIARWLPLMSSGSLESFHYPRMRDGLYRRTIIVVPDLGALVSTSVGHQRESGATFLTLEKATVNCYAKEFSDYLSVCKPMTKTHGGAQMCNMLLLRALGYESTFSSCIQQSGSLSSITMPPSVVKNIISKTKIPASQKLLRRLREDAWHFEDIVKEHRIIDIFPLAPLEEIAAGKVPVAASQILCGDTCYYSMIEYKLHLQHIAALLKKHPNYHLIQNCGEHIRSDIIYIREGNLALLYKDTAPASIIEITESNLITELWEYMLREIEPKLSPAAREDVIARIERLVMEIDDNLPAGQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIF6</accession>
    <name>A0A010ZIF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441868.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_0"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="234" mass="26315" checksum="A8679C4ADA9270EF" modified="2014-06-11" version="1">MITQTTANLADAAYFALKNKILRGELKSGFPLREEQLSESLGVSRTPLRKALTQLLAEGFLVKGKDRTLRIPYISTSELKDTLKARRLIETAAVAEACNRATEKDITRLEHLIWDEKEALRMHDNLMISSIDMMFHNCIAQASGNKIYSEFVGILGYKISLYLALSNTLGEDIVTALEEHKIIVNAIKLKIASKASAAMNMHLDNVERRMLESIEKTPNTHGQTEETIFPLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIH9</accession>
    <name>A0A010ZIH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prophage antirepressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484856.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_942348_0_0_0"/>
    <dbReference type="OrthoDB" id="872571at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003497">
        <property type="entry name" value="BRO_N_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02498">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01040">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51750">
        <property type="entry name" value="BRO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bro-N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="295" mass="32730" checksum="0D5BF992974789A5" modified="2014-06-11" version="1">MTNTLQIFENHNFGSIRTVLDESGKALFCGKDIAEALGYSNTKDALIRHCKGVVKRDLGVVTGKKADGTDAIQNVAVSFIPEGDVYRLIVRSNLPSAEKFEHWVFDEVLPAIRKTGGYITSTPDDSDADIIARGYRAAIAAIERKDQTIAALEAQREEAAPYTDLGRAVSEKAGYMLISKAAVIMAQAGCMFTVQETGERRIIGVQYLRIYLEQKEFIVKRGRSDAGRPTIKGQKYQRVQMKASPLECGAVAYSPVLSSDFVKMLIKMFHKKEMVLPKIVKNDRKAKQNDEEDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIV9</accession>
    <name>A0A010ZIV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid ABC transporter ATP-binding protein, PAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0747</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="262" mass="28916" checksum="7CA0D37978E8F231" modified="2014-06-11" version="1">MNTTNKPLIIIENLCKSFEDGDVLRNISFTIREGDLASIIGPSGCGKSTFLRCINCLELMDSGSVTVAGVTVSRKPGEVPSDAMLQKVHELRTEVGMVFQSYNLFPNKNLLQNIMLAPMVVKGMKKDEAHELGMKMLEKVGLKGFAQKYPSTLSGGQSQRAAIARALAMNPRVMLYDEPTSALDPELVGEVLQVMKDLDAEGMTQIIVTHEMKFAKDASDYIIFMDKGEIVEYEDGDILFANPKNDRTRAFLRHFVNAGVTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJF8</accession>
    <name>A0A010ZJF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xaa-Pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710902.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.966"/>
    <dbReference type="HOGENOM" id="CLU_017266_4_2_0"/>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="6"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="148"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="368" mass="40581" checksum="50111C25A7F19BEF" modified="2014-06-11" version="1">MIKKKRVERLAQTLKDRGIDALYIGPSTDLEYVGGLDTQPDERVRGLMVAKDARCFAMTPLLYKEEIVKAFEDVPFYAEWNDHEGFTGAFRRGCEHLGIVGGRIAFNDGVRAVDMLAVRDAMPMEMVNGADLLAGQRSRKDEEELEVLRESSRIVDKVVAKLQKFIRPGIKERDVAKKIPEFFEEEGVTQMSFNPIVASGPNGSMPHYSGGERVIGENDIVILDLGGRYKSYCSDTTRTLFTGTPTEEMKKVYEIVKRSQAAGEAAVRPGATGQDVDRAARQVIIDAGYGEFFFNRVGHGVGLAVHESPYMIEGNDVPLAPGNVFSVEPGIYLPGKFGVRIENLVAVRPDGSGEALNHFTRELTICGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJJ9</accession>
    <name>A0A010ZJJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator with HTH domain and aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710967.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_6_0"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="50"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="401" mass="44454" checksum="9E471658C2FA7C87" modified="2014-06-11" version="1">MSTVNWNTRLSEIALNVKPSPIRALLKYTKTPGVISFAGGNPDPAVFPVAEFSEASQILAREGKDVLQYGATNGYEPLKEYIAKWMAPRMGRETKSDEMLITTGSQEGMDLLCSVLLNDGDTIIVEGPTYPGALHAMRNRGARFLSVPCDKDGLRVDLLPQVIEQGRKDGHNIKFIYSIVNFQNPSGATLTKERRAKLLEIAEKYDLVIFEDDPYGHLRYNGEHVPTIFSMDKGGRVVYACSFSKILAPGTRVAWIVGAPELIQKMVMIKQGTNLCTSVVAQALVYEYCRLGHLDGFLPKIIAHYGKKRDAMDAAFKKHLPANTRYHTPEGGFFFWLQVPGVDSTKLFMKAIDHGVAFVTGPSFYAGEGEGLDYMRTCFTFAQPEEIEEGVKRLAAAIKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJN3</accession>
    <name>A0A010ZJN3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="6" type="ORF">Cloev_1009</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1078"/>
    <dbReference type="HOGENOM" id="CLU_074407_2_0_0"/>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="117" mass="13114" checksum="E8DF05AB04D43D1F" modified="2014-06-11" version="1">MRHRMNTRRLGRCSSHRWAMLGNMAASLFIEGSIITTETRAKELRRVAEKLITKAKAGTLNDRRLVIARIPHKEAVTKLFNELGPKYADRNGGYTRIVKIGARVGDASPMAVIQLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJS0</accession>
    <name>A0A010ZJS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="7" type="ORF">Cloev_1058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711149.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1126"/>
    <dbReference type="HOGENOM" id="CLU_040318_1_2_0"/>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="275" mass="31302" checksum="563D6BB527F7AD20" modified="2014-06-11" version="1">MGVVSMKQLLECGVHFGHQTRRWNPKMKPFIFTERNGIYIIDLQKTVKGLEKAYDFVREVSKSGGSILFVGTKRQAQDPIRDEALKAGQFYINQRWLGGLLTNFATIRRRVMRMTELQQMEEDGSINKYPKKEIIQLRKERDKLEKYLSGIKDMKDVPDAIFIIDPRRETIAVLEAHKLDIPVIAIVDTNCDPDVVDYPIPGNDDAIRAIELVVGLMANAFIEGRQGQDSRVAEKEEAAAAEETPAEPPVEDISEDEMKLRAKELADQKGWKETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJW4</accession>
    <name>A0A010ZJW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="2">CMK</shortName>
            <ecNumber evidence="2">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ispE</name>
        <name evidence="4" type="ORF">Cloev_1107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053057_1_1_0"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_C" evidence="3">
        <location>
            <begin position="211"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="288" mass="31908" checksum="E327F9DFB750FFF2" modified="2014-06-11" version="1">MQSIINSPIKINLTLRILSRRSDGYHEIYSLFWQKRAVERLTIRANCDEIIGDFLEVTGMPIIGENLVTKALTAARECAANIPPLKIRLDKFFPAGSGIGAGSGNAAALLKWLRENFRLEMTEKEIGRLGADIAFLASDSEMAAARGIGEILTPGGEAPKLGWVLAFPKWSSDTKEAYAKLDAMRAENKNEAPPSEEEIAAEAAECLRRLREGHRANRLPNDFFPILTEEHREYAVAEEIASETGARGWGLCGSGSAFFGLYADREEALRAEKIYNNEGWILKTFNME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJW7</accession>
    <name>A0A010ZJW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepA</name>
        <name evidence="7" type="ORF">Cloev_1112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711229.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1185"/>
    <dbReference type="HOGENOM" id="CLU_009995_3_3_0"/>
    <dbReference type="OrthoDB" id="182107at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="4"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="603" mass="67238" checksum="F20911E9EA1AE6CC" modified="2014-06-11" version="1">MKLENIRNFSIIAHVDHGKSTLSDRLLEATGTIDKRNMKAQLLDRLDIERERGITIKSVPVRMNYLAQDGREYILNLIDTPGHVDFSYEVSRSLAACEGAVLVVDAAQGVEAQTVANSYLAADLDLELVPILNKIDLPSAHPEQVKRELEEIIGINAEEAVPVSAKTGEGIPELLERIVRDVPAPVGEAEAPLQALIFDSVYDNYKGVICYVRVMNGTLAAGKNVRFMATGRDYQIDEVGVFKPDMLKVERLGPGEVGFICASIKTIDEAHVGDTITDSAKPASAPLAGYKKVKPVVFCGFYPVEREDINQLREALEKLQINDSAISFEPENSAALGFGFRCGFLGLLHMEIAKERLNREFGVDLVATAPNVVYQIVQTDGSIIEAHRPSDFPDPVRIEEIREPYIKLSIFMPEQFVGAAMQLCQDKRGTYVSMDYITPERVRLTYDMPLAEFILDFHDRLKSCTRGYASLDYDHTGFRASKLVKVDVLLQEEPVDAFSFICHADQAYHRGHAVVGKLKELIPRQLFEVPVQAAVGKKVIVRMNIKAVRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKQVGRVSIPQEAFLAFMDVTKAEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKY6</accession>
    <name>A0A010ZKY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0029 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008708517.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.20"/>
    <dbReference type="HOGENOM" id="CLU_083552_1_0_0"/>
    <dbReference type="OrthoDB" id="1777855at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="23"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="219" mass="24673" checksum="1CB1A67AE9D85AE1" modified="2014-06-11" version="1">MADDRLSIFRAPRKDCDAEFTEKRSRFIGSVRIALNADEAAEMIKKFPELYPKANHHCWAYRIGGGAALEHCSDAGEPAGTAGRPILGAIKRHELTNTLIVVTRYFGGIKLGVRGLIDAYKAAAELAIERAGAVEMEFSNALLLRCGYDYSKTLSSTLRKWGFSEERVNVEYGAEVVMRLEVPFSMRAEIEAPLSEMAQRSFLTELRWDEVPLVRERWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZKZ3</accession>
    <name>A0A010ZKZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding domain-containing protein, AraC-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.32"/>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="171"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="274" mass="31647" checksum="8F132AD33B053968" modified="2014-06-11" version="1">MREKRRPVRRLWRRKSLRGMDFLTAENLPAERAASHLHHGYTISIVEDGILPVNFREFKLDLKPGDFLILGPDVPHNFNFSPQMGRCSYRTVFVKEEYLSNELKTAIARENLTISCFSDLTMWEDYLNIQRGIESGSESDIGEIIGRSEKLLSRMPDFVLSRMLVRSPHILTVKEYLKDNFAAAPNIEELAKIAHISPFYLMRLFKEEIGLSPHAYINQLRINKAKEMIEDGMPLLQITYELGFTDQSHFSKTFLKVTGVNPVHYGNIQRTVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL34</accession>
    <name>A0A010ZL34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum ABC transporter, periplasmic molybdate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0076</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709834.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.90"/>
    <dbReference type="HOGENOM" id="CLU_065520_3_1_0"/>
    <dbReference type="OrthoDB" id="1506401at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004846">
        <property type="entry name" value="ModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458199" evidence="4">
        <location>
            <begin position="23"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="255" mass="27371" checksum="8A33292BF01CBCF1" modified="2014-06-11" version="1">MKKLSFLALICAVVLAAAPAFAATELSVFAAASMTESMNQIAQMYQKVDPNVKIVYNFDSSGTLKTQIEQGAECDIFISAGQKQMNAINDKFVMPGTRFNIVANKVVLIVPKGKNATNIRSFGDVVTDKVKLIALGNSDVPVGQYSEEIFKNMGIWDRLKSENKITFASNVKEVLAQTAAAAVNCGIVYSTDAATSNAVEVVASAPKDTHKPIVYPAAIMKNTKQKAAAEAFVKFLKGDACSDVFKKIGFAIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL55</accession>
    <name>A0A010ZL55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441291.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OrthoDB" id="1048863at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG77997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="253" mass="27477" checksum="44E00146CFE74E0D" modified="2014-06-11" version="1">MSLYTFRGLCAGYGAKKIIDGISGEIERGRITALIGPNGGGKSTLLRALGGLGSYSGALAFGHREVSGIPRRDFGRLVGFLPQNISVRAAFSVYEIISLGRLPFHGALEPMKPEDDRIILESAELAEVGHLLFRAATELSGGERQRVLFAMTLAQQPELFLLDEPTSALDPSHSRRIFSLLRKLAAEGRSVVAAAHDLNGAISCCDDFIALKEGKIVARGPVGLLDEKILQELYGIKFRRYRSEDGDTAWHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLH0</accession>
    <name>A0A010ZLH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinose efflux permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0217</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441393.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.235"/>
    <dbReference type="HOGENOM" id="CLU_001265_10_14_0"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="384" mass="41177" checksum="E866C5744A8DA107" modified="2014-06-11" version="1">MRKDRTVIGLNLPAFLMMIGVGMIVALFPQRIIDFDGDGRRVGYVASMFALSYIAFQVPVGALADRFGFKRFIALGYLLCFFAGLGYYFSSGSIMIFLGRLIQGAGEAPVWALAPALLSVKFSSDKGSSIGLYNAICYVGLTAGPILSVFLINRWRYENMFLLYAFACLAGAVLTLWLVEDVRPNGESPGKVDFSGVREMARDGAALLTLIGITVYGAGYGVFVTALPVFLMSEKCFGHSLVSAFFSLFYIAISIAQLTTGRASDRFGPSRFMALGLLFAAIGTAAAPFLFSIRLLAALTLASAGLGVFYLASMIFLNETVDERLKGTISGAYYLFFGVGLCFGPPLFSLVMGMVGCANSLICLAALFAAFSAIMAAGLRRFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLH5</accession>
    <name>A0A010ZLH5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase_H_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484793.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035904_2_0_0"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="2">
        <location>
            <begin position="90"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="415" mass="47095" checksum="31DDBEDEBC6CC792" modified="2014-06-11" version="1">MARPQRNSPEKFGRLDGLLPRAEGKIEPGPQNLPRELDIDGLPEGRWIARGVYRMEREFEYGRWYGKKMLASPEESGRVLCHWGGNAAPVFLDTETTGLSGGTGTYAFLIGLGLCGAASFRVVQLFLAGPAWEKSWLAAIEAELPERYGLVTYNGRAFDLPLLRTRYTLARAVPSWNGAQHMDLLTLSRHFYKGRLSSCSLSSIERNVLGLRRGGEDVPGSEIPWMYTQFLRTQDAGPLRGIFYHNTLDIVSLAALQIHIAEMARGECSCAADMIRAGDLWAAKGFQAEARAAWEGALDFSRDRHLALLRLAETERAAGNYESAYRYYEESLETERRPVRTLEAMAKIEEHRFRRCEEALAHATEALRWLESHRIFKDRQWEEDRKNLLHRIERLKRKIAGKECGEETHPDDGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM66</accession>
    <name>A0A010ZM66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441668.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2153962_0_0_0"/>
    <dbReference type="OrthoDB" id="2021248at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="111" mass="12743" checksum="9EA7FD016CAEB50C" modified="2014-06-11" version="1">MEWFKALKNGEFSMPVTFWFCNVGVSFVAYVLFLFIFTTFRAPIISFILLVIFALVYKPLVLLGMWRSANDYDGPTKWSFFVKIITVFAWFEYLAILCVTVGIAASFIGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM97</accession>
    <name>A0A010ZM97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441726.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_575830_0_0_0"/>
    <dbReference type="OrthoDB" id="1790144at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="474" mass="52393" checksum="7DB6CCAD08F58A03" modified="2014-06-11" version="1">MPVQSRKNPNSKDKVYSDFRGGGLNLGASERFLSEKEVAGGKNFCYERNGGRFRTLEPLELVATAAGTVTSLYWSLNFGMIFSCGQALYRIVDGAPVSIGTLSGTDLPVYCDWGEEAERRLFVASGSIIQWYDGKQFVTQTPVPVDKTDPSGGDKWNTANDVMVREGRLLLSRTGRDRLRYSGIGDPENWQSEDEGSGDDIDVHTDADAQWLDVGYKEGGDIVRILPISRDLVIFRSDGSLYRLFSSFPDWTVIRVASQVEPVNRDAVAAVGNDIMFLDKDRGIRKVSAISDNDTDLAVTEKEGQKINAWLAAHFTNDARLWTLPDRGEIWVKPNALNDVFCWNERYQGWTRIDLGSPVTAACEADGTVYLALGAKIYRLTDSSVSPAIRPEMEIELAPVFGSDRAMTDYQELCVTKDAAAVAELEIGRWRFAASGSKTVKHQIYVADELRPVLRSSGGTVVLDKLTIRTAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMH0</accession>
    <name>A0A010ZMH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709696.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2536667_0_0_0"/>
    <dbReference type="OrthoDB" id="2190999at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="83" mass="9468" checksum="A97649C780B94362" modified="2014-06-11" version="1">MTARTMRYEQKPFGTIKIKTLAVFLLPSALLLSFIVEPKLLYASFALAATFAYGALLNIFVFRRGAETYRMLNIVLEKIFNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMJ5</accession>
    <name>A0A010ZMJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484848.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_1_0"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="291" mass="34011" checksum="F3C8795F190F6600" modified="2014-06-11" version="1">MTKIYSTNEICKLCDISRKQLRYYEERGMLAGVLRNENNNYRFYTIEHIKQIIAAKELKNIRLSLDEIRELFFEHSISGVQLTIEKKIQSAKEDVEQSLLRYEQTMVVYARLMEAVAIFKNHLSNKNHREELSYEVVDFPARDIISLKYYATFEDEERQAIEQAAKIQVAAKDVNVAALGSLIYLTFDHFDSENCVFDNKRHLMKAAMPVVSTDKQCAYYDRIERFKGVSTLHFGDFPVSLKETYIGLLKWAKEKGYKLANNSVEEWLIGSTITNNQNYWLLRVIIPFAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMQ3</accession>
    <name>A0A010ZMQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PLP-dependent enzyme possibly involved in cell wall biogenesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0659</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441907.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_7_2_0"/>
    <dbReference type="OrthoDB" id="1722208at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="392" mass="42181" checksum="AF174A56263BA910" modified="2014-06-11" version="1">MAGAEIFNSDEIRAVADVIERKMIHRYGSHDSRGGIYRAEDFEEKAKRLTGSKYALALSSGTAALITALKGICIKPGDEVITSPFTFIATVEAIVACDAVPVFGELDETLSLDAASAEKLVTPRTKAIMPVHMFGVAADMDKFAALGEKYGIPIVEDACEVVGGTYRGRALGSLGTCGTWSFDPNKTLTVGEGGMVFTDDHDIWYRMDCYHDHGHIHSKEHDRGAEGKFGLGVNYRISEVQGALGVVALEKMPQALAALRAAKKKIIDAGIAAGLTPRPMHDAEGDTATHVIFMLPTAEAAKRFQAAAKEAGAGCAIIADNTWHYAKHWKALEEMGGREYFGSRTPSYAPETMAQPESLLSRAVMFGLNIRMSDEAVERIERAVRAAAKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMR5</accession>
    <name>A0A010ZMR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid:ferredoxin oxidoreductase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441920.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.714"/>
    <dbReference type="HOGENOM" id="CLU_017038_0_0_0"/>
    <dbReference type="OrthoDB" id="360732at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR_N" evidence="1">
        <location>
            <begin position="14"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="PFOR_II" evidence="2">
        <location>
            <begin position="248"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="353" mass="38427" checksum="E8460EAA94B18918" modified="2014-06-11" version="1">MTKVLMKGTEAIAEAAVQAGCKYFYGYPITPQNEIPEYMSKRLFEVGGVYLQAESEVAASNMILGGAATGERVMTSSSSPGVSLMSEAMSYIAGQELPVVVVNVMRGGPGLGGILPSQGDYNQATCGMGHGDFNIIVYAPSSLQEAVDMVQRAFDTAQKYRNPVMILCDGIIGQIMEAVEIPAQEPRNLSNPAEWAAGYMRERGRRNILQSLFLTPEVLEKHNQKLEAKWHVIEQNETACEKYLTDDAEVVIAAFGTVGRIARSVVEAMRAEGFRVGLIRPLAVSPFPRMDFAGLPACRHILDVEMNWGQMLKDVKLATESRIPVSFYGRSGGMCPGVAEIEDECRKIFAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMS5</accession>
    <name>A0A010ZMS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type branched-chain amino acid transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710469.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.724"/>
    <dbReference type="HOGENOM" id="CLU_027128_6_1_0"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458370" evidence="1">
        <location>
            <begin position="24"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="26"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="379" mass="40480" checksum="C1B7BD4F07194306" modified="2014-06-11" version="1">MKLTKSVAVAFSLVLVMAGMAMAAETVKIGVYLPITGGNAIGGQLELDGVKLAHQQYPTVDGKKIELVVVDNKSDKVESANAVKRLIEKDKVRAIIGTYGSSLAMAGGEVAEKAGIPMVGTSCTNPLVTQGKKYVFRVCFIDPFQGAGAADYALKELKAKSAAMLIEVTEDYSVGLGNFFKQNFTKNGGKIVSVMNYQKGDQDFTAQLTEIISKKPDVLYIPANFAEGAIIMRQARELGAKFSILGGDAMDNPEMVKIGGDSVEGFSYTTFAYSPNMAEKLMSPIQKQFTAQWRKAFPGKDPAALTGCGYDAYLLIYNAIKSAKSTDPAKITAAIASTKDMPGVTGTTTINKTHDAEKSVGIIKIEKGKQVFHAIVNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMY6</accession>
    <name>A0A010ZMY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0735</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441979.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="71"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="254" mass="27854" checksum="4CEAE4C71582E55D" modified="2014-06-11" version="1">MKEDLQYINSIMRAINILEIMAEEGLSMGITDISKRLDLHKSTTFNIVKTLEKCGWLVQNKQTNLYHIGFGPLKVAASALQNNNERDAILHEMETIAQTINEDVVLSAVSSGVGLCIEKCVSNNALVTSSKPGSTVPLHRGATGKILLAFQSEKFIDAVYQDNQDDIPVSRQQFEESLRKIKAQRYSFTSAEFDDGVSAIAVPVMDAGGAFLYGLSVAGPIARIEEKGVSDIVCQLTQAARRITDHIRILSIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZND9</accession>
    <name>A0A010ZND9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrothymine dehydrogenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dihydrouracil dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydropyrimidine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484879.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.919"/>
    <dbReference type="HOGENOM" id="CLU_042042_4_2_0"/>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044512">
        <property type="entry name" value="DPYD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073">
        <property type="entry name" value="PTHR43073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="407" mass="43747" checksum="E914D6AFA12820BE" modified="2014-06-11" version="1">MRENLRTNFLGVEMPNPFMLASAPPARDRDMIDRAFQAGWGGAVIKTLTQYTGEEGSEIRDVSPRIFPIRGSGGVFKNVVFGYMNIELTSQKTNEESCEDISFLKKRWPDRAVIASILYGHAPIKEKWQRAAADCELAGADAIELNFSCPHGCSEIGSGVSIGGNPAKIREIIGWVKEATRLPLITKLTALSDIVYAAALSEECGADAICAINTISSMPGIDLETFRPRMNAGGVGTAGGLSGHMIKPIALRSVLEIARAVKIPVSGSGGIYDWREAAEFILAGASTLQICSAVMEQGYGIIGGLCNGLSAYMERMGFKDIDAFRGRALGSIVHHADIDRGRLFKPYLDIMKCSCCGKCAVSCRDAGYQAITLSRGGVRIELERCTGCGLCYGLCPNEALTPVETRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZP14</accession>
    <name>A0A010ZP14_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_1130</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711267.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1203"/>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_0"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="9"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="418" mass="44192" checksum="49960A5F553D49DD" modified="2014-06-11" version="1">MTPMNNRRVVITGCGAVTPIGIGKEEFWNALERGENGADFITQFDTAQHTTKIAAEVKNFNPENWLDKKEARRTDRVIHFAAAAADLAVKDAALDIEKLDSNMFGVYVGSGEGGIHTLEDNALVLYEKGPNRISPFMVPMMITNMPAAYIAIRVGAKGPNMAVVTACASSINSMGEAYNCIVRGDADVMLTGGAEAAVSPLATAGFASLKALSNRNDDPKHASRPFDSGRDGFVIGEGAGILVFEEYGHAKARGAHIYAEVVGYGLSCDAHHITAPDPDGDGACRAMAMAVKKAGWQPEEIDLINAHGTSTPLNDKMETMAIKRLMGEEAAKKVLVHSTKSMVGHALGAAGAIETIATLLAVEKGIVHPTINQITPDPECGLNTVPNKAVKAKVDRAIINNFGFGGHNGVLAIQSCKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7P8</accession>
    <name>A0A011A7P8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cobalamin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441367.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469093_0_0_0"/>
    <dbReference type="OrthoDB" id="146745at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="2">
        <location>
            <begin position="458"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="591" mass="65489" checksum="89F2E21F9503384C" modified="2014-06-11" version="1">MIISLKDRIADILKETPLPKAKDVTDESHRLAAEINIGRTKFMDKYDVSSELEYKRRCVKEGRIMYHAHIGMNTWNETVIALGEVYDFAEKNGFVLDRAGICLDRRMSLPPELRKSAPQETGPYLETEGDWRQVGQAAPIQPHMGDFIIGFPASTVNAMAALRAGVTTVGNLSQFFAHEAPMWKRTDITTVETVKAIGIMGALREKGTLMHSYLDDGFGALFLDCATSAAWAYLERYIVEDLLGAKLAHCVGGLVSDPIKRTGWVFALDEIHDHDCIGSMFYGDTISASSVPEENRSLAAEYLIWDIMAQLECPTGHGLMPVPFTEALRAPSLEEICEIQQWAREMERIARRMHPHFDFTASRSFAASICAKGKGIFKNALDFFADCGVDTRDAVQLLYILKKIGPRAFEDELNPGARDKEKTSAGGEPIPNDIFTRTLEQVDTWRPHYESGEVREKLSGIKVLLASTDVHEHGLLLIDRLLTAAGALVDNIGAERNPDEVVSEAAKHRAEMVFISTHNGMALEYARNLLDEMEEEDYKVPVCMGGVLNQNTAEGTTPVDVSGELEGMGVTVVTDLRLLPERTAAAKKRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7Q4</accession>
    <name>A0A011A7Q4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF2179 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0196</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709305.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063199_1_1_0"/>
    <dbReference type="OrthoDB" id="1747063at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006483">
        <property type="entry name" value="Membrane_protein_YitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="237"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="300" mass="33722" checksum="58E2B483498A1E39" modified="2014-06-11" version="1">MEYRIDQIKWKHLYRKAQLLFFSEWKTMLISMAAIVIYAVGVVGFTIPYKFADQGVMGIAVLLKYTLGFNPAYVLLILNIILLIWGAKTLSKRFLIWTVINAFVLSAVLDLLQTISFPMMDDIFLVAVAGGVIKGLGIGLLYREGISAGGLDIAITVLKKRYGMEVGRLSFYFNMVILAVSFSVIGLEKVMYGFISCYICGMTMDSVLASFDKRRLVFIVASNTDAVVEFINRKLGRGCTLLSSEGGYKRRDGFTIMCLLMPRQVVELKRFLAEHFPGSFMVVTEANEVVGKGFKRWRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A842</accession>
    <name>A0A011A842_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="118" mass="13805" checksum="3B782CAC0C4F78BE" modified="2014-06-11" version="1">MTEVGKIYITEASNKTGLSVETLRYYEKVGLIPRVERTDAGLRRYGETDCCWIEFIKCMRDAGVPIDVLVEYVLLYQQGESTRQKRSLMLAEQMRLLDEKIAELQRTREKLRMKITSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A887</accession>
    <name>A0A011A887_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig-like domain-containing surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441539.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_335162_0_0_0"/>
    <dbReference type="OrthoDB" id="633672at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011493">
        <property type="entry name" value="GLUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07581">
        <property type="entry name" value="Glug"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="826"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="527"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="851" mass="86008" checksum="36213B078A1DF340" modified="2014-06-11" version="1">MNEPATTNKKHVRSIGAIALILAITVISGLFAHYMPTKSNAEDVRIPQAFIINTSADLALFRDNVNNGTSSDIYAYLSTDIVLSGDWTPIGTEGHPFSGTFIGGCHMISGLTITASKNQYAGLFGYVKGGAVENLTVDASISIMGSTHALYSGVIAGRGESAAFLNCTATGAVGLVVSTNNNVYGGGIVGYLSGINSKILNCSSALGSVAAEVGASTNYQAYCGGIVGYNGGGTITNCAATGGIEAESPIDTTYAGGIVGYNMGGKITNCLANAIAGGADSTTGTTYMGGIVGYNDGSSAITNCSASGTAGVEASSAPSIIGGIAGYNHNSATITNSASAIALTTEQHGTYIVGGIVGINSGDITNSGWLSTTASFDVGEGEHGKFAVVSYDAALSNDVVTTCLPNLLASTDLVPKQLVVTVGSTDQYMLKTYPGKLGTQASFDSYVTNSAFGIMDTALAEVAVNAASYDHADVTGKAVGGTHATNAMKLCATDFSNIGNPINTPLDLTGDDNIPKLSIGVVEIKVPVTAISVDKKIASTAIGNLVYIVATVTPADATLQRITWSSSNPAVATVSPTTSLSGASVGVKGIAEGRTVITATSDNGGFTASCDVTVTKEGPIVVDDPFSPIKPVLPADKPSGVEATLVKIAVAADKAAILSGTRLLPADLTVNGKGQLIVTDAIASAAVNSAIEGKNLTVVKINNLPIAAASLDILGDTSTYAYEVSGDKLLADSLSELKLVKILPGGKGELFSVATKSADFKDKYVTLLKSGTSTIHTDAIVPTDTYTLVAFVKDGQSFDLDEAANGVVIDPMAVLQAKTQGGGGSSSGGCSTGLAGLMLLAVIPLVLKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8D2</accession>
    <name>A0A011A8D2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Pyruvate:ferredoxin (Flavodoxin) oxidoreductase, homodimeric</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Cloev_0361</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.393"/>
    <dbReference type="HOGENOM" id="CLU_002569_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037112">
        <property type="entry name" value="Pyrv-flavodox_OxR_EKR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000159">
        <property type="entry name" value="NifJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="682"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="736"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="966"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="995"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="691"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="694"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="697"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="701"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="745"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="748"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="751"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="755"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="811"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="814"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="816"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1075"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG78251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="1170" mass="127972" checksum="E66DAAB5E6BC87BD" modified="2014-06-11" version="1">MKEKKLVTMDGNEAAAYIAYAFTEVAAIYPITPSSPMAEKTDAWSAKGKKNIFGQTVSLIEMQSEAGAAAAVHGALETGALAASFTSSQGLMLMIPVLHRLSGQRHPGVLHVAARTVGTHAFSIFGDHSDVMNCRQCGLAMLATGSVQEIMDLAGVAHLAAIKARIPFMHFFDGFRTSHEIDKVEEMSYETLASLLDREALAAFRAASLNPERPMMRSTVQNPDIYFQVREANNGFYDALPAIVEEYMEKISGITGREYHLFNYYGAPDAEEVIVAMGSVSGTVEEAVDYLNARGRKTGFIQVHLFRPFSLKHLFAVLPATVKKIAALDRCKEMGSNGGPLYQDICTAFTGTGRGVTIVGGRYGLSSKDTDPTQIIAVFDNLAKAEPKNDFTIGITDDVTHLSLPLGDAVYPDGARQMSFKFWGLGGDGTVGANKNTIDIINSYTDKYGQAYFEYDAKKSFGVTISHLRFSDGPIRSSYFVKRADFVAAHNQTYIQNYDIVSELKEGGTLLLNCPWEPDELEGKIPADIRRKLARKRAKFYIINATKIAEKHGLGSHVNIPLQSAFFHLVDLIPIDEAKQYMKDAVKKTFFAKGDEVVSRNIAAIDDGGAMLVKVDIPDSWLDAQDAPKPRRAGEPAIVEKLLAPINRQQGDSLPVSAFKGYEDGTVELGLTAFEKRAIATSVPEWDPARCIQCNRCSYVCPHAVIRPYLLTEAEKEAAPEGFLTMPAIGQKDMYFSMQVSRDDCTGCGSCVTVCPSKEKALTMVPIEKSKSLPEQWAYGLTISDKEGKFDPWTVKGSQFRQPLLEFSAACAGCGETPYAKLMTQLFGDRVYWANATGCSQAWGGAMPGIPYTKNKDGKGPAWSNSLFENNAEFSLGMFLSVKQQREAQRLRAEKLLAAGIPAALKTALEEWLAAFDDFNGSAAAAKKLTAQLEAAQLTDEAAAAAREMLANKDQFSKKSFWMYGGDGWAYDIGFGGLDHVLAMGENVNALIVDTEVYSNTGGQSSKSTPIGAVAQFCISGKKVAKKDLGAMLMTYGNIYVAQVAMGADMNQLIKAMREAEEYEGPSVVIAYTPCLAHGIKGGMGSAQEEMKRAVAAGYWTLYRYDPRKEKPLTVDSKAPTMDYEEFLDGEVRYSALKRTFPENAKKYFKEGSEEAAARYARYKHIEENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8G2</accession>
    <name>A0A011A8G2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M15_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441602.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124897_1_0_0"/>
    <dbReference type="OrthoDB" id="2028958at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013230">
        <property type="entry name" value="Peptidase_M15A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08291">
        <property type="entry name" value="Peptidase_M15_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M15_3" evidence="1">
        <location>
            <begin position="28"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="114" mass="12570" checksum="55E55E62D3A2DEC4" modified="2014-06-11" version="1">MRLNDFQISPNFNLREFQCPCCHAVIVHRKLVSLLQRLRERQGGPLVVTSGYRCAPHNAAVGGVANSLHRRGLAADVAVAPAAQRTFCEMAKEAGFAKALAYPERSFVHLEVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8T7</accession>
    <name>A0A011A8T7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484841.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.591"/>
    <dbReference type="HOGENOM" id="CLU_029469_2_1_0"/>
    <dbReference type="OrthoDB" id="275025at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="199"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="459" mass="51297" checksum="B6550039B5324B51" modified="2014-06-11" version="1">MNGCETGALKKVYKYIDENMDLYIDWLLEAVRQPSISMYNSGMNEMASLCVHFLEDKLGLKTNIIETGGSPYIYAYLDEGAKDTLAFYNHYDVMPVEPLEEWESYPFEPVIRDGRIWGRGTADNKGSMFSRICAVHACKQIYGKIPVNLKFFYDGEEEIGSPHLDDFMLVKGGLLECDGFFWEGGSRDLERGRPHITLGVKGICKIELSCRTAGRDLHSANAAIVANPFWRLVWALASMKNDKEEILIDGYVDDIAPLSDKERKIIHDMSFDEEASLRSYGISSFLNGDKGGALKERLVNSPTININGFKGTSSDTETKTILPGNASVFLDLRLAVGQTPESAMKKIRRHLDRKGFSDIEVKLKSSYDPFRTSCESALMKAAVQSAREIYGMEPNIILNDWGSSGVCAVCGRLDIPCVMIGVMNEDSREHAPNENIYVEDYNCAIKMIASIITKIPCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8V7</accession>
    <name>A0A011A8V7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">H+/gluconate symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441823.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.614"/>
    <dbReference type="HOGENOM" id="CLU_027949_0_2_0"/>
    <dbReference type="OrthoDB" id="1585405at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="449" mass="46534" checksum="5AB573DD055DBD4C" modified="2014-06-11" version="1">MTGIPLIVVFVLAIVVMIVAISKYKIHPFLSIMTVSLVFGIIAGVPIAELPKTIGEGFSGTFKSIGIVIIFGALVGTLLEKTGAALKMADLVVKVVGKKHPELAILIMGWIVSIPVFCDSGFVILNPIRKALTKRTGTSSVAMTVALSMGLYISHCFIPPTPGPIAAADSLGIGDHLLLVILLGAVLSIPPLVAGYLFALYIGGKVKARDDEEDASLVKSYDQLIAEYGKLPGGCASFAPIIVPIILMALASGLAMAKINCPVIAFLGTPVIALAVGVILGVVLLASARKMDEFYAITNDTLMIVGPILFITAAGGVLGKVISVSGMVQYITANSNVLSTIGIFFPFVLAAILKTAQGSSTVAITTTAGMLAPVLPALGLDSPVLAALCVIAIGAGAMTVSHANDSYFWVVTNFGEMEPQQGYRTQTLGTLVIGLASMLGVYIAYMVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8X2</accession>
    <name>A0A011A8X2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic-acid-binding protein, contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484845.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121449_2_0_0"/>
    <dbReference type="OrthoDB" id="1842663at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="135" mass="14978" checksum="BC3093D86D99BC44" modified="2014-06-11" version="1">MATFVDANVFIRFFANDDKVQSEAAEKLFQKARSGAAELLTGPPVFFEIAWVLGYRYKIKSEEIMDILESIVGWPGISVLDETLVLKAIALARETKSEFADAYIAASAGNAGANDIATFNKKHFIRLKQELCQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8Y7</accession>
    <name>A0A011A8Y7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1560280_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="171" mass="20012" checksum="6B08D09E57B7F625" modified="2014-06-11" version="1">MLSINVLKGVKYVPETLVNKISSSNKHRLIDCRYIDVLYSPCWIFAFGAVFRFSQAKQKFVGYLGGVDELTLSPGTVTALPETEEIKVMEKNVLSDKITEARAEELAWEYSKRWVIRKNRILHKVPEKTQTHSYKVYKPLYLFEFYKKEEERTFYKIMDSLTGDLENIELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A906</accession>
    <name>A0A011A906_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441875.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.672"/>
    <dbReference type="HOGENOM" id="CLU_017779_9_2_0"/>
    <dbReference type="OrthoDB" id="1188552at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="48"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="478" mass="52628" checksum="425B9D7516EC7640" modified="2014-06-11" version="1">MEANFSYSPVTDNTVADLIAIFGRSGVSVDREKIEAYSKDEVAPHLWEKKYEAEVVCFAETAEQISRLMEYANEYRIPVTPRGAGTGLSGGAVPAYKGIELSLERMNRILEFDAENLTMTVEPGVITSDINKAALDNHLMYAGDPCSGDASFIGGNVAENAGGNKVVKYGPTGSHVLGMEVVLPDGAVSWFGGKRRKDVTGYDFVHLMVGSEGTLGIVTKIILKLLPCPSFIVDLLVPFADVGSAIKAVPAVMTEGKCVPSSIEFIDKQSMVLTEEYLQTKFPFSREAGAHLILQYEGNDREHLADEIEKVGDICLKQGALEVFVADNRTTKDKLWKGRKSVAEAVWAHAPIQIANEDVVIPTSRAADFMKELENLCRGAGIKYAAYGHLGDGNMHVTLYLEREEREWREIIEAARRRLYAVVIKFGGTLTGEHGVGLKRVEYVPLFIDRAQIELIRRVKLAFDPNNILNPGKMVPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A989</accession>
    <name>A0A011A989_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator with HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086997_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="266" mass="29753" checksum="DAD1F5190B319F65" modified="2014-06-11" version="1">MLRSGYKKEVLAFVNTDGGVLSVGISRDGKVVGAEDPDDAMLRISSALRDSIRPDVMPFVQLRAAEREGTAVIEIAVQTGTARPYYLQDKGLRPSGVYVRRGSASIPLSDEGIREMIIQNSGKSYEDCRSMEQDLTFRAFESEMAERSVELGDSQMRPLHLIGEDGLYTNLARLLSDQCGHTIKTAIFQGTDKAVFRSRQEFSGSLLKQLRDVYQLVDINNKTKATFSGLNRTDFAVAEPQSCRGILSYEADRELWDRHWENHPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9D6</accession>
    <name>A0A011A9D6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ethanolamine utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EutP/PduV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710659.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.816"/>
    <dbReference type="HOGENOM" id="CLU_113298_2_0_0"/>
    <dbReference type="OrthoDB" id="2003468at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006576">
        <property type="term" value="P:cellular biogenic amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012381">
        <property type="entry name" value="EutP_PduV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40453">
        <property type="entry name" value="PTHR40453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10662">
        <property type="entry name" value="PduV-EutP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036409">
        <property type="entry name" value="EutP_PduV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR036409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="151" mass="16169" checksum="E1C44DD7AE341A81" modified="2014-06-11" version="1">MSVAGKGRRVIFIGASMAGKTTLTQAMMREELRYRKTQTLDIVGGFIIDTPGEYLERGGLRGALSVASAEAGLIVFLQSAAAVQSFFPPAFASMFGKPVAGVVTKADIASPEEIEEAKRRLARAGVKRVFVTSAYTGEGIQEFIDFIDSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9P4</accession>
    <name>A0A011A9P4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.935"/>
    <dbReference type="HOGENOM" id="CLU_044208_1_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="214" mass="24098" checksum="F27EBD75422C9BAA" modified="2014-06-11" version="1">MEALSSFLSCGIQLFGDLIQWLVEVIGHLGYPGIVGLMFLESSFFPFPSEVVIPPAGYLAWKGEMNIFLVIFSGIAGSILGGLFNYWIAVRWGRPIFEKYGKYFFVTHESLDKAEVFFARHGHISTFTGRLLPVIRQYISLPAGLARMPLAQFSFYTALGSGIWVVILALVGYFLGSNQAMIHQEMRKISLCLIAACAVLIVIYIFIYRRRQHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9T1</accession>
    <name>A0A011A9T1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type spermidine/putrescine transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710878.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.953"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="322" mass="35484" checksum="1FAF20B39AE16EC7" modified="2014-06-11" version="1">MTTLRARNITKRFKGTTALDKVSFEIRDGEFVCILGPSGCGKSTLLRALAGLEAIDGGTIEIGGRDVTCEPPSERNFGIVFQSYALFPNLNVEENIAYGLWNKGLAKDEIAARVAGIIEMTGLGGHNKKYPQQLSGGQQQRAAICRALVLNPEFLLLDEPLSALDAKVRLRLRREIRRIQQRFAITTIMVTHDQEEALSMADRIIVMNEGRIEQMDTPQALYDAPVNGFVADFVGTANFVGAGRAIRPESLCLSKSLSDSAVQAEVCDVEYRGAFYRLEVDTHVGHLMIDIPSQQSDARVLRLGSRLYIDIPQDKVIMLKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9Y0</accession>
    <name>A0A011A9Y0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proline--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="7">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proS</name>
        <name evidence="9" type="ORF">Cloev_0956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442247.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1026"/>
    <dbReference type="HOGENOM" id="CLU_001882_4_2_0"/>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="32"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="480" mass="54557" checksum="0BE5F1AA3D01F222" modified="2014-06-11" version="1">MAKNITPKEKDYSQWYLDVIRAAEMADYAPVRGCMVVRPTGYAIWELVQKHFDDAFKETGHVNAAFPLLIPQSFLSKEAEHVEGFAPECAVVTHAGGEELEEPLIVRPTSETVIGHMYSKWVQSWRDLPILINQWCNVMRWEKRPRLFLRTSEFLWQEGHTAHASKDEAVEETLRMLEVYRRIMTDYLALPVLEGEKTEGERFPGADNTYTCETMMSDKKALQAGTSHYLGQNFAKAFEIQFQNRDGEMEFAYTTSWGVSTRLIGAIIMTHSDNDGLVLPPRIAPVKAVIVPISTSGEKIEKELMPKAAELKAALNEALGGRFVSIDSQFHMRPGDRFFSHLQRGVPLRLELGEKEYAAEKLRVVRRDTGEKLEIAWADAPAAIPALLEEIQQNLYRRALEFRLANTHRADSFEEFKMLLEEKGGFIEVFFDGTKEDEKAIKEATGATPRCFPFAHSEERGKCFYTGKEGARKAIFAKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA02</accession>
    <name>A0A011AA02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplW</name>
        <name evidence="10" type="ORF">Cloev_0981</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710986.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1051"/>
    <dbReference type="HOGENOM" id="CLU_037562_3_2_0"/>
    <dbReference type="OrthoDB" id="1978865at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="98" mass="11084" checksum="A0AFA7157A7B71FF" modified="2014-06-11" version="1">MNAIAYDIIVRPIITEKTSRQMELGQYTFEVLPKANKIEIRKAVEEVFKVKVVKVNTIQVRSKPKRMGAFLGRSRSWKKAVVTLAKGEKIAFFEGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA06</accession>
    <name>A0A011AA06_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplP</name>
        <name evidence="9" type="ORF">Cloev_0986</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710993.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1056"/>
    <dbReference type="HOGENOM" id="CLU_078858_2_1_0"/>
    <dbReference type="OrthoDB" id="1786618at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="139" mass="15665" checksum="180B8B940E54E254" modified="2014-06-11" version="1">MLSPKRVKYRKPHLTALRGYSKGATEVDFGEFGLQACENGWITARQIEAVRVAISRKMKKGGKIWIRIFPDRPVTEKPLETRMGKGKGNVEYWTAAVKRGRVMFEIAGVPRDVAELAFRTASFKLPIKVKMLTREGAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA28</accession>
    <name>A0A011AA28_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">L-lysine 6-transaminase</fullName>
            <ecNumber evidence="2">2.6.1.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Lysine 6-aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_1016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + L-lysine = (S)-2-amino-6-oxohexanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21200"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="EC" id="2.6.1.36"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.36" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711038.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1085"/>
    <dbReference type="HOGENOM" id="CLU_016922_10_1_0"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045484">
        <property type="term" value="F:L-lysine 6-transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017657">
        <property type="entry name" value="L-lysine_6-transaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03251">
        <property type="entry name" value="LAT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="455" mass="51412" checksum="A8DF5B5FB8504365" modified="2014-06-11" version="1">MPSNCSVAPKDVFSTIEKLLLRDGFDIVIDMEQSKGSHIVDSASGAKWLDFYTFFASSPFGMNHPKLDNPEFKEKIFRAAINKVANSDIYTQEMAEFIKTFGEVAVPEGYNHVFFIDYGTLAVENTFKVAMDWKVQKLLQKGKVTPGEAYNGRKGTKIMHFNEAFHGRSGYTLSVTNTNDPNKHQRFAKFTDWPRIINPKISFPLEDHIGEVEWLEAQAIKQIKQVLMDDPDGVAAVIIETIQGEGGDNHFRTEFFQKLRQICDENEMLLIFDEVQCGMGITGKMWAWEHHAPVKPDLFSFGKKAQICGLIAGPRVDEVKDNCFKVSSRINSTWGGTVVDMVRAQKYLEIYRDEKVLDYVSNVAGPALYAGLKELESEFPGYIRNVRGKGLMCAYDICCPELRDKFLKECHKNNMLILGCGSNTVRFRPALNVPLEDLQLGIDISRKAAQAVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA91</accession>
    <name>A0A011AA91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hydrogenase, Fe-only</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_1092</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442408.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1161"/>
    <dbReference type="HOGENOM" id="CLU_018240_2_1_0"/>
    <dbReference type="OrthoDB" id="323168at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003149">
        <property type="entry name" value="Fe_hydrogenase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036991">
        <property type="entry name" value="Fe_hydrogenase_ssu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013352">
        <property type="entry name" value="Fe_hydrogenase_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02256">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00902">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="SSF53920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02512">
        <property type="entry name" value="FeFe_hydrog_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="8">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="565" mass="61594" checksum="AE91C4A134062951" modified="2014-06-11" version="1">METKKYMTIDGLPVEISGEKNILEVIRKAGIKLPTFCYYSELSIYGACRMCMVENKWGGLDAACSTPPKEGMEIWTNTERLRKYRKMILELLLADHCRDCTTCGNNGKCKLQELAMRFNIDGVRFPNGAETPRRDESSLCITRDQNKCILCGDCVRMCNEIQRVGAIDFAGRGSKMTISTVFDIPISESVCVGCGQCAAVCPTGAIVIRNDSAKVWKALDEKETRVSVQIAPAVRVALGKELGIGDGENAMGKIVAALRRIGFNEVFDTSTGADLTVLEESAEFLARLGEGEHEMPLFTSCCPAWVNYAEKNEPEVAENLSTCRSPMQMFAAVIKEHHKHSPRKHVHVAVMPCTAKKAEAAREEFRGELGPDVDCVITTQELIQMIKESGLVFSELEPEAVDMPFGTMSGAGVIFGVTGGVTEAVLRRIVSDKSAAALQAIAFKGVRGNEGLKEATVKYGGRELKIAVVSGLGNAHELIGRIKNGERYDFVEVMACPGGCVCGAGQPFVLHEGKESRGKGLYSADKMSSIKRSEENPLMMALYSGLLKGRVHDLLHVHYRANGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCG2</accession>
    <name>A0A010YCG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484734.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1599848_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458757" evidence="2">
        <location>
            <begin position="24"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="166" mass="16917" checksum="CDAE2A51BB1FD21F" modified="2014-06-11" version="1">MRFLNRSAAALTLLLFAAGGAFAAPPGPPPGQKMPMGPGPVRINGSMPAMRGNGGPRPGGPGPLMRPMPPGPGAMRPGGPPMGPGAVRPVPPRPNMGHGPMRPPVGPGPQLPNYRGPGWQAHPQPYYGPYRHRDRDDDDNTGKIVLGVIGGLILGGILSNAAGSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCH6</accession>
    <name>A0A010YCH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase, histidine kinase/DNA gyrase B/HSP90-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441220.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020211_10_0_0"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032834">
        <property type="entry name" value="NatK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14501">
        <property type="entry name" value="HATPase_c_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="523"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG77940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="627" mass="67812" checksum="3D0061AC82FCD1FF" modified="2014-06-11" version="1">MNPGRVPLALRVAAAAALSALFFILICKFDNKYTYPSPQPIGGVLWLDAAALKKHPAGFLRDGWIVYPGKLLTPREIREGKWRREEIRIGGGALTDGKSPVGAATYHLRIRLPEEERGYALELPEIFSAYKLYVNGHETEQVGDPAAGLELTGARLISFRAASSADIVIAAANRNHFYGGLVYPPAFGETRAVQRIILARLARALAVVAFALASAAASLYFAVALAYVPARLYSLLCLAFIGSSSYPIIHALFDLPLRPWYALEIFCGYLAIALAVTLHNRICGVTGRCARVVECAAYLVAAASLAYGLLSPRLPFAAELFPEMIFLYKSAVAAYLIKGAIGAGTAGKTESSPLPLLCADVFFAASILFDRIYPEFEPIITGWFPEMGTFALVAAIGIQLWRDLAQAWRERRALRENERRAEKELGIHLSYIEALREKIDENRRFRHDHRQLLHTLTALAAGGDEKTLHEYIKNLENAAPPASAVKYSENAVIDALIGHYAAAAKKNGLPFDVIAPIPADFALSDTELCRVLGNLIENAADAAAGAKAPYVRVSGSETNAQSIIIIANSYGGTIKKRGGKYLSSKHEGAGLGIASAQKIAEQNGGSLIIETTEKTFTATLFLPKAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCN8</accession>
    <name>A0A010YCN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709873.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1370244_0_0_0"/>
    <dbReference type="OrthoDB" id="1834410at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="199" mass="22442" checksum="C404C1B463BEF3B8" modified="2014-06-11" version="1">MEIEESGIGFIFHNDRVVKFDDSEFYRRYFNCLPHSKGVDFVCEAGGKRALIEVKNCLGHEAENIWRIGSDNAKREVVTPSPGDDRESLDIEMSLKAAMTIACLCGALSKERGCSHAETLSDICRPLGNVGLGGEPLYIILFLEGNFYFETRSKKMIMERLQTSIRKKLSWLNCSVSVTDSSTYKKKFFTIRQNQTGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCR2</accession>
    <name>A0A010YCR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441320.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_394674_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="1">
        <location>
            <begin position="465"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="698" mass="75431" checksum="F643B8726787DA6E" modified="2014-06-11" version="1">MSKLLRQIVFLVLMGVLVAVSGGCGGGSDSKYPVVNADGAILPKDPTNWTAAEKSAWINQGTLLLDQMVSTEFRGRMAGDIGYEQAAMWAATNFKAWGLEPLDGSYFQDFNISYSMPINKSPVIKILVDGKVWKSTENGDYIDDEFVKDIMSAHGTNTGTVRSKLTFLGYGIDATAANVYANTEFKHINPATVYRNDFNEYAGLTWDSGSDPANDIPNKTLLDVADRVVIFRNATPNSLSNVDYRPTPILGGALEAEEYKYTVGNDWIRHDEHYVKIGVARQRKAAGVLYNQMVANPNIRYQPPVGDNVFQIALVGSIGRNTKDGTLSETTYTNGTGDSRLLNDLFAKQLEIEAASGGAKHTLTDLITRAKAVKSPNKDGNGPVRSVPMKNFGDGKGDVPDYPQFLYQATADLFKGPDSTVGALNSPYDKNYDASIATNSFNFDDRIEIEITTEAQSRVDAKAMNVVGVVRGSELPDEYVIYMTHFDHCGFVGPYMTAGAADNGGGSTANMIAARYAAMMAAAGNKPKRSLVFILDGAEESGMNGAKKAAAWFAANGREKVKAVFHTDATFGKGHGEITLSTSMSAGLAPLVDELLDSSQGRHHPWGQDASDVNPGATITMSTPTSTGQAKYVGRPRTDTAAWQDEDMPVVVNVSAREQDSTTSLYHAPYNDRDYVADRLLAILGIATANNMYTVANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YCR6</accession>
    <name>A0A010YCR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709224.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.149"/>
    <dbReference type="HOGENOM" id="CLU_1187991_0_0_0"/>
    <dbReference type="OrthoDB" id="1066272at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="230" mass="24744" checksum="B04E147673F48803" modified="2014-06-11" version="1">MQCSREVEEMVCVAKGANHGPAPIPEEGKWIESRQIGDISGFTHGVGWCAPQQGACKLSLNVKGGVIQEALVETIGCSGMTHSAAMAAEILPGKTILEALNTDLVCDAINTAMRELFLQIAYGRTQSAFSDDGLPVGAGLEDLGKGLRSQIGTMYGTLEKGPRYLEMAEGYVLDQALDKNGEIIGYRYVSLGKMMEAIRKGMDPKEALEKNTAAYGRYAEAAKIIDPRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDD7</accession>
    <name>A0A010YDD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NCAIR mutase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441507.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.355"/>
    <dbReference type="HOGENOM" id="CLU_065705_0_0_0"/>
    <dbReference type="OrthoDB" id="1744359at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039476">
        <property type="entry name" value="P2CMN_synthase_LarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064">
        <property type="entry name" value="PTHR43064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="1">
        <location>
            <begin position="119"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="251" mass="26006" checksum="379E692F497F75CE" modified="2014-06-11" version="1">MERKELRNLLERLSAGAADVDEVMTKLRGEPFRDLGFAKLDSHRVLRQGIAEVIYGAGKRPEQIAEIAGAMLADGQRTVLITRMSAEAAAVVEKTVPLSYHEMGRVGIAGEMPRPDGRGKIVIATGGTSDMPVAEEAALTAEALGNEVTRLYDVGVAGLHRLLSHTDDVMTASAIVAIAGMEGALASVIGGMADCPVIAVPTSIGYGASFGGLSALLSMLNSCASGVSVVNIDNGFGAAYLASMINHIGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDE4</accession>
    <name>A0A010YDE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709005.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.360"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_0"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="296" mass="33416" checksum="81AA409E44DC3A0E" modified="2014-06-11" version="1">MEIRVLRYFLTVVREESITKAAEMLHITQPTLSRQLAQLEEEVGVRLFRRGARGIALTNEGILLRRRAEEIAELVDKTERELLEQNELIDGTVSIGAGELASVQLLGDIIKSCRTKHPLIRYEIFTASADLTKERMDKGLTDIGLLLEPINIEKYEFIRLDVKERWVAVMPADDPLAAREYVTADDLMTGPLILPIRGGVRNELLSWFGSSFDRERVILTHSMSTNASIMVQKGMGRCVTVEGSLPYLDNNVLALRPLYPELTSTSVLAWKRQQPFSLAATKFIEHLKCFLGMTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDH1</accession>
    <name>A0A010YDH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase-like amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.382"/>
    <dbReference type="HOGENOM" id="CLU_068979_12_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="202" mass="22011" checksum="B179EEA9A9FEEF41" modified="2014-06-11" version="1">MPPPKGMVWMSEKLEFMIVVDMQNDFVSGSLGSEMARAIVPDVAEAVERFISEDRGRLIFTKDTHEENYLETSEGRHLPVPHCVRGTWGNEIIPELAGYASREGAVIVEKKTFGSVGLPGIIRAAAAEDKGKKSADGTAGESFAFYLLGLCTDICVVSNALLLKANFPEASFRVDSRCCAGVTRKSHEAALETMKMCHIEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YDW5</accession>
    <name>A0A010YDW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease component of ribose/xylose/arabinose/galactoside ABC-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.551"/>
    <dbReference type="HOGENOM" id="CLU_042763_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="366" mass="39774" checksum="7537CBC7DB47F770" modified="2014-06-11" version="1">MANKMKGRCAKDLLADYAVPIVFLGLSVVAIPLSGFSAVYLIQEMLTRLARNSFLVLSLLIPIFAGMGLNFGMVLGAMAGQIGMIFVTDWAVSGCYGMLLAALVGMPIAIVLGCICGAVLNRAKGREMVTSYILGFFINGIYQMVVLYGMGKIFPISNPQLVLSRGYGIRNAINLTGLRHVLDNLIPLKVYGIDVPLATFILIGFFCVFIVWFRRTKLGQDMRALGQNMAVAESAGIPVERTRIIAILISTVLACFGQIIFLQNIGTMNTYNSHEQAGMFAIAAILIGGASVSRATISNVFVGVVLFHLMFLVSPMAGKELIGQAQLGEYFRVFVSYGIIALALVLHAWKRQRNKIEARRSLRGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE36</accession>
    <name>A0A010YE36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase, IS30 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.633"/>
    <dbReference type="HOGENOM" id="CLU_046274_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="241"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="438" mass="49845" checksum="8BA363B6EFE2DC45" modified="2014-06-11" version="1">MKQYKHINGNDRVAIQLGLERGDFFKTIAEAIGKHPSSVANEVRKYREFKKCGAQGNVFNDCAHRFDCRKTNLCDSPQCRRKNCRFCARCRDHCGEYELERCAKLAKPPYVCYGCRQKQHCTLEKAFYDAGIANQTSLNVLSESRMGINADEEDMECWTKTIVPLIKRGQSLYHILHTTSDTANLPSQRTLYSYVEKGGLSGVCSLDLPRQVKYKKRYVKRTKTDTAYRKGRSHEEFLKYMEENPDTPLVEIDSVVDAGGKHAILTMHFVEISMMLAYLRNGKDSQSVVNIFDTLTESLGLEKFRELFPVILTDNGSEFSNPEMLEKTSSGESRTKIFFCEPYSSYKKGAIENNHELIRRILPKGISFEGLAQKDITDMMNNINSYARKKLNGHTPYDMFSFLHGAESAGLLRELGLKAVKAKSVLLTPSLISRKQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YE59</accession>
    <name>A0A010YE59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484854.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620695_0_0_0"/>
    <dbReference type="OrthoDB" id="313921at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="25"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="427" mass="45461" checksum="6A2770C1E2BE2C49" modified="2014-06-11" version="1">MPGDGKAGGVRKKIIFPRSEGIIYEAKISSSAITAAAKPKPFAPVIDIEALVRERLDAPEILFLSSAARESGGALIICDDITRPTPTGKIIPALSDFLAANGVPVEKQHVLFATGTHRAMNAKEAEKKLGASYGRISWSNHSYNAALLRIGVTAGGIPVDINPVVKEYACVIGVGSVFPHRYCGWSGGGKIILPGVSGATAVAATHWMPYEDPSITLGSNDNLAMREIASASDIAGLSFLIQVICSGDGKVMDIVTGRPAPAHRRAIEIASRHMKVTMPQSDIVIAEAWPEEADLWQAGKALYAAENIVSDGGDIIIIAALTEGFGPHRLYAELMNKSVSEIISYRNGDENSSIAAAAAFVTAQVRKKAKISIVTNSPYSANITEVTGIRTYKTLQEAVDKVFSLKKTVAVLYQAPLMLPVREETVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YF10</accession>
    <name>A0A010YF10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710904.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.967"/>
    <dbReference type="HOGENOM" id="CLU_705475_0_0_0"/>
    <dbReference type="OrthoDB" id="703457at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024258">
        <property type="entry name" value="DUF3798"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12683">
        <property type="entry name" value="DUF3798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458083" evidence="1">
        <location>
            <begin position="24"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="396" mass="43994" checksum="36861AF228C8793E" modified="2014-06-11" version="1">MRRATVFLFALIAASFMATAAFAAPAFHIGVATLTVSQAEDTYRGAERLIKEYGDVANGGMIKHVTMPDNFMSEMETTISQIVGLADDPKMKVIVVDDAIPGTTEAFRRVKEKRKDILCFAGEPQEDPNVITSTADFAVGVDNIMRGYLIINTAKKLGAKTFVHISFPRHMSYELLSRRRAIMEQACKDLGMKFAFETAPDPTSDVGVAGAQQFILEKVPAWVQKYGKDSAFFCTNDAQTEPLLKQVAKYGAIFVEPDLPSPLMGYPGAFGIDLKKEAGNWPAIMKKVEKTVVASGGKGRMGTWPYSYGWSTVCALAEYGKRITEGSAKLYNLKDLWKCYDKYTPGAEWNGAPYYDMAKQMKIKKFVLVYEDTYVFGRGYMGVTKEKVPEKYIKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFB4</accession>
    <name>A0A010YFB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484905.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982241_0_0_0"/>
    <dbReference type="OrthoDB" id="1390120at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="285" mass="31377" checksum="40AD4E15AEFE06FA" modified="2014-06-11" version="1">MKKIEPRRGAFLALRVLAVVFIFLLGCRGAEASAAAVMKIAVTSPWLYEVASFVGGRQVQVRALSSWNEAGNTVVTGRPRGGELVIAFDPADATRFRIGPQNKNLKLLYQKTPMDEDKLRAAFFDPAMLPFIAQEIMKIIAAADQKNYSYYQRRLAEFQSRIDSTMGVGRHLLSGANILDLTGAEGTWVRSSISGVVRPPESVWTGWLAGDAAALRAALDEASRRGWLLLLDPWTPDVIRAAASAYPYRLTLPVPPKDTEFFVFLHEIFTIIAGRVKSAAPKVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFC4</accession>
    <name>A0A010YFC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ORF">Cloev_1085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442392.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1154"/>
    <dbReference type="HOGENOM" id="CLU_003601_3_3_0"/>
    <dbReference type="OrthoDB" id="177859at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="555" mass="58934" checksum="0A31270E97B21EB1" modified="2014-06-11" version="1">MKTDIEIAQEAPLLKINEIAARCGVDEKYIEQYGSYKAKIDYKLLKETAKPDGKLILVTAITPTPAGEGKTTTTVGLADGMRRIGKNAVVALREPSLGPVFGIKGGAAGGGYAQVAPMEDINLHFTGDFHAIGAANNLLAAMLDNHIQQGNALGIDAKKITWRRAVDMNDRQLRNIVDGLGGKAQGVPREDGFDITVASEVMAVLCLAADITDLKERLARMIVGYTFKDEPVTAGDLHAAGAMAALLKDALKPNLVQTLEHTPAFIHGGPFANIAHGCNSITATRMAMKMGDYAITEAGFAADLGAEKFLDIKCRMAGLSPTAVVVVATVRALKHHGGLAKSELNSENLEALEKGLPNLLRHVDNIKNVFGLPCVVAINAFPTDTKAELDLVEKRCGELGVNVALSEVWAKGGEGGMALAEEVVRLCDGPNDFKFSYELEKPIEEKLDAICRRVYHADGVQLTSGAKKQAQRLTELGFGDLPICMAKTQYSFSDDAASLGAPDGFTITVRNLKVSAGAGFIVALTGDIMTMPGLPKVPAAEKIDIDENGVISGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YFD5</accession>
    <name>A0A010YFD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Addiction module antitoxin, RelB/DinJ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelB/DinJ antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711197.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1167"/>
    <dbReference type="HOGENOM" id="CLU_154558_0_0_0"/>
    <dbReference type="OrthoDB" id="2086657at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007337">
        <property type="entry name" value="RelB/DinJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04221">
        <property type="entry name" value="RelB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02384">
        <property type="entry name" value="RelB_DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="101" mass="11128" checksum="6B746531EBE2CC87" modified="2014-06-11" version="1">MEKSTTLNLRVNPTVKMQAEDVLKQLGVPMATAVDMFLRQITLTGGIPFEVSLPKVPAAVNADAMSAERLRAELMAGYEEMRQGSTQDASTAFARFRESHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSB0</accession>
    <name>A0A010YSB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.127"/>
    <dbReference type="HOGENOM" id="CLU_197468_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="56" mass="5825" checksum="BDECD0AE2E397419" modified="2014-06-11" version="1">MIATIVISILLFAAVIAILMKINKDRREGKSSCGCGGSCGSCSGSTICHPPKKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSI6</accession>
    <name>A0A010YSI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="1">PPIase</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.222"/>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006511431" description="Peptidyl-prolyl cis-trans isomerase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="35"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="187" mass="20101" checksum="24979E4DC612AD31" modified="2014-06-11" version="1">MMKILALSAMVAAAVMFPFAAKQAEAADAAEAAPKRQVATFETNYGTFKIELFNDLAPKTVKNFVDLAQKGYYNGLSFHRVIDQFMIQGGCPKGNGTGGPGYNIPDEFGKGLKHDKPGILSMANAGPNTGGSQFFITLVPTPWLDGKHAIFGHVTAGMDVVEKIGKLPTDSMDRPLKKVVMEKVTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSJ4</accession>
    <name>A0A010YSJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig-like domain group 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.227"/>
    <dbReference type="HOGENOM" id="CLU_326985_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030821">
        <property type="entry name" value="Synergist_CTERM"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04564">
        <property type="entry name" value="Synergist_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458834" evidence="1">
        <location>
            <begin position="23"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="768"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="880" mass="91882" checksum="D8D83DD451A875C4" modified="2014-06-11" version="1">MKRSILIFAALCALLTAVVSTAAVSTGGVLVKQQDGTTRDISIPVQDDNDRWLHNVETASLYGAWDNVEMAIWGISSDNTLLNLIISGDFDFKKTDPNRGWFNAYGGKDCYNEPLDIKGDTKLVVTGDKNAKIDLDNGGISLFGGASLYASYGGDIQGSTLLVLQGESPTFTPDKDVDENINLYGGSAIGNDGIKIHTIHGDSSVMINAPWDLGDNDRDISFVIGGSDVQGRSKVVTKGKTYVLIDNKKASATNVRGGGRASDSSTCVIDGGSELLFKNGSIGNAYAGCYASQHAKAYTAKTYVEIRDISAPGDAMITGGGVSGSNYDLDDPTMVCINVVSGDTYILVEPSAGYTGKGVCRIFGGSNIRGAGATAEILGSTNIVISGDAALNVIKPQNPEKDWTHISAGGFRKNNKTISNDVKGDGNITFKNITNISKLMNNTALGGQGRERDDDMPGNLGFYDNSVVGTSRLIYDNVQGVTGARTFLFDEIIFKNGSNVTFNRSLSQLYSDDDRDKETVTLVVEKGSTLRISKDPTGDTGNPVLGNAKIDGTLIVDEGMTLVLNNSLEVGEGASVKGSVVVKKVEPVKPPVKPESEGVIPVKAQAVNTIEELPANVAVLVEKQPNGELVVTSSKFISAVLSSDISGTVDTDLIKSMPVIKSAVSADKTALISFKARLDEFSSKKFSDLVLCKIIPGKVLKFALQSVPEKIKSGEFTVTAADGKAVDLNGSPSAGTEYLINLAVADNSEYDLDPAKGAILDPAVLTVNKEKLTLSATELTLFVGESASLKASGYAAGAALSWQSGDKSVAAIEGSGAEVTVKALAAGTSDIAVSDGTATVTCKVTVKPGTSGGGSGGGCDAGIGVIALAALLPFAWRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSK9</accession>
    <name>A0A010YSK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ORF">Cloev_0224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441399.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.243"/>
    <dbReference type="HOGENOM" id="CLU_027272_2_3_0"/>
    <dbReference type="OrthoDB" id="751464at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="4"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="363"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="471" mass="52801" checksum="9329B6BD0DC20884" modified="2014-06-11" version="1">MWKGRFAQDTDEAVINFTQSLDLDWRMAFADIRGSVAHVRMLAHTGLLDAKEAETIEENLRGIAEEIRSGDFTPKVSLEDVHMNIESRLIEKCGATGARLHMGRSRNDQVNTTVRLYLRKELLGIWEGLESLISVLIKKAEEQADIVVPGYTHLQQAQPISMGQFWMAHAQAFMRDAKRLLAAYDSVDESPLGCGALAGSTLPLDREFTRADMGFSRLTENSMDTVAHRDHFMDILYFAAVFGGHVSRLSEDLIIYFTTEFGWVKLPDSFCTGSSIMPQKKNPDVLEILRGKSGQLSGALVDLLTMTKGIPLTYNRDLQDDKRSLFRTLDCLNGIFSVLPALLSRVEIDEEKANRGFADGLILATDVAEYLVLRGVPFRSAHEKVGHAVRWCIENNRPMDGLTLAEWQRLIPEAEAGLLPLLSPRRSMERRDTVGGTSPRQVRAQIARARERLAAYESEMAEYGDKLPDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSP7</accession>
    <name>A0A010YSP7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisH</name>
        <name evidence="11" type="ORF">Cloev_0259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441430.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.280"/>
    <dbReference type="HOGENOM" id="CLU_071837_2_2_0"/>
    <dbReference type="OrthoDB" id="1726024at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="4"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="205" mass="21812" checksum="726E39BD9B52A1F6" modified="2014-06-11" version="1">MIAVIDYGAGNLKSVKNALDHLGAANMRASTAKEILLADAVILPGVGEFGTAMAELERRGIKEAVIEAANGGRPLLGICLGMQLLFEAGEESPGAKGLGILPGRVPRFPAEMGLKIPHMGWNSVMPLKENRLLDGLPKGSYMYFVHSFYVKAAERADVSAISEYGLIFDAAVERGNIFGCQFHPEKSGAAGLVILKNFIEIAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YST8</accession>
    <name>A0A010YST8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multimeric flavodoxin WrbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.328"/>
    <dbReference type="HOGENOM" id="CLU_050993_6_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="44"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="219" mass="23525" checksum="A7C8186175ACC4B3" modified="2014-06-11" version="1">MNRRDFIKASLTAAAVTGGTLLGAPLLAAAQPANVGRKAGDKKMKILVITGSPRKNSNSGALAAQFIRGAKEAGHETARFDAALKNVHPCSACSHCGMDGPCVYQDDFSFVREHLVPADLVAFATPMYYFGISAQLKSVIDRFYALNGKIHVHKRAVLMMTYANTAASEAAPIISHYNVLLKYLGWEDAGQIIVPGVWPEGAVNNTKYVEAAYRLGKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT00</accession>
    <name>A0A010YT00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative selenium-dependent hydroxylase accessory protein YqeC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441557.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068045_2_1_0"/>
    <dbReference type="OrthoDB" id="1717694at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017587">
        <property type="entry name" value="YqeC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19842">
        <property type="entry name" value="YqeC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03172">
        <property type="entry name" value="TIGR03172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="254" mass="27287" checksum="48197B29BCF26ED0" modified="2014-06-11" version="1">MRELFAFLAGYMDRNEAALAAVTGGGGKTSLLYGLGRELAASRRVLLSTTTKIFRPTACECRDLFLGPAKLCAAFIGAMPPASLLAAAAGEREGKLIGYAPEEVCALAGCGAAGAVVAECDGSRGRSLKFYEEWEPPVPRSCGCLFAVAGIDALGETADEEHIFRADRFRALHGMAEGAKVSAADYLSYLRHPEGPLKNAPRGAKKMLLLNKWERAGEEARREFAEAVPSLLESYDAAAFVSMRLNILYDCRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT02</accession>
    <name>A0A010YT02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stage II sporulation protein E (SpoIIE)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709058.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.409"/>
    <dbReference type="HOGENOM" id="CLU_703441_0_0_0"/>
    <dbReference type="OrthoDB" id="533349at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="391" mass="43014" checksum="84E063CFCA233816" modified="2014-06-11" version="1">MDSICIDACYNSLIKKNEELCGDRVQVINSPESMLLVLSDGLGSGVKANILSTLTSKIISTMISRGASIEDTVDTIAHTLPVCKVRGIAYSTFMILSIRKDGSGYLAEYDNPPCMLIRDGRHIPFEYEEKTIEGKLVRESRFTAREGDYFVIVSDGVTQAGMGETLSFGWGCDEVADFLCGPCGEKLSAPRVINRVLDVAKDLYLGKPGDDTTVSIAHILPRQPVSLFSGPPKNPEDDSRLVRDYIETRGLHIVSGGTSSEILARELKRPLRVNIDYTDSDIPPTAAIEGIDLVTEGVMTLKRAIEMIGEYIDRPAVPNMISELDDPHGAAKLAKILIEQCTHLNLFIGKAVNPAHQNPDFPTELRVKSRLMDDLAAVMTRLGRHVEKKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT17</accession>
    <name>A0A010YT17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441600.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_196603_1_3_0"/>
    <dbReference type="OrthoDB" id="2088243at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="72" mass="7260" checksum="914A089A3E25CB55" modified="2014-06-11" version="1">MASIKHLTSALRLTLSLGTVDGKSVTKTVSVSKIGAAAGAETLNALVGALGGLLEHPVASVKKYDTGLLEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT24</accession>
    <name>A0A010YT24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative endonuclease containing a URI domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441616.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135650_0_3_0"/>
    <dbReference type="OrthoDB" id="2077602at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="96" mass="11326" checksum="EA1E22F7883752C9" modified="2014-06-11" version="1">MSAYTYILRCADGTLYTGWTNDLERRLRAHNAGRGARYTRPRLPVELFYYESYETKEEAMSREAFIKKMPRRAKLLLKIRKISDKTTCESQLQGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT48</accession>
    <name>A0A010YT48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PRPP-binding protein, adenine/guanine phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709149.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.478"/>
    <dbReference type="HOGENOM" id="CLU_080904_3_0_0"/>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000310">
        <property type="term" value="F:xanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023747">
        <property type="entry name" value="Xanthine_Guanine_PRibTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39563">
        <property type="entry name" value="PTHR39563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="168" mass="18975" checksum="48C9D65EEB99ADCF" modified="2014-06-11" version="1">MAETASRYHKNYPVSWEQVQRDCRALAWKLLDIRSDWSRLITVARGGLVPAAIIARELNIRLVDTVCISSYTMRDQTAADILKRPDLVGVDEKWLIIDDLVDTGKTARIVRGMFGPAHFATVYAKPEGRPLVDTFVTEVSQDTWVLFPWDTAPTTAFIPPIADMNLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTA7</accession>
    <name>A0A010YTA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Zn-dependent protease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0522</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709631.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026425_0_0_0"/>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="29"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="123"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="234"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="453" mass="47981" checksum="C3DC656214C33BD9" modified="2014-06-11" version="1">MIKFLPHDEVEALAAHALDLAAKSGAWGADLLYSEGSGSGLTLKDGETEECASGSSAGIGIRTIMSDGRQGIAYGSRLDKASVDSLVEWSLHNALASEPEEGITLYEGPLVRCRELDAEDRRIREITAADRMKYCLEMTREARSLDSRIVSVRSASWRDGWGASFFATTKGLCGWEEGSSANCGVMVLAQSGESTEMGGYGMEALRLDELDIIKSARTAVEQTVASLGGRQLATGSYTIMIEPETAASLVDVIGGLFCASDVHRGRSMMKGRLGELVASPCVNLTDDGRIPWKPGSSSWDSEGVPTGRTELIKNGEANAFLYNLQYAIKDGVSSTGNCSRGMSSLPDVGTTNLVFAAGTESPDALRARITNGMYVTEFMGLHTIDPISGDFSIGAKGHRIENGEITTPVSGVTMASNLLEFMRNISAAASDLKYSGSVAAPTLVVENVVIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTD5</accession>
    <name>A0A010YTD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441805.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055360_1_0_0"/>
    <dbReference type="OrthoDB" id="1359310at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="PTHR21198:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="231" mass="25748" checksum="7D62A299FF56A590" modified="2014-06-11" version="1">MKTIGIVGGMAWQSSAEVYKIINELVNKKLGGQHSCQCVMYSVDLDPVLILRDEDDWEKLNDIMEDAVKRVEAAGADFTMICSNTMHKTVSAIKNRVSKPILHIADVTAQAILDKGFKTVGLMGTKFTLTQDFYKDKMEKDYGIKILIPDEDDIAFIHHVIYEELDYSIFSPASAKRFVEIIEKLHQRGAEGVILGCTEIPLLVKQEDTSVPLFDTTTLHAEAAVKLALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTE2</accession>
    <name>A0A010YTE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">P-type ATPase, translocating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0563</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441819.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.603"/>
    <dbReference type="HOGENOM" id="CLU_002360_3_3_0"/>
    <dbReference type="OrthoDB" id="178322at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="628"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="696"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="734"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="771"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="799"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="833" mass="91040" checksum="860E744E9A8E7BEF" modified="2014-06-11" version="1">MAEITERYCGLSAAEVEERRGRYGRNVIAEEEGKNPLKKVLKFFSEPVFLLLIGAACLYFFLGEPRDGAVMLIFVAFMGAINIYQEWKTDRTLEALKSLSSPKVTAVRGGEVVTVPSEDLVPGDIIILSEGERISADGDVLENDGFGADESTLTGESEIVWKVCAPQGKAGRGWRTDRCYAGTNAVAGRAVVCVTETGAHTEYGKIGADVALAPDRPTPLEKQTRRLVRDCSVFSLLMLIFVVAATYYRGGGIIEAALSGVTIAMATIPEEFPVVLTVFLALGAWRLAKRNSLIRRIPSVETLGAVTVLCVDKTGTLTENRMSLKRFTPLCGTPVQKLTEVAVLASETNPYDPMERAIIDEAAKNGIDVKRLQGQRLLHEYPFSSESRMMCHIWAYRGKVLAAAKGSPENILKLCSLTPGERERAESEQRRLAEEGCRVLAVAYNDDMKDIPEEMEECSLNLAGLAAFIDPPRENVAESIRACGGAGVRVVMITGDNSVTAHRIAHEVGLGCGEKEHVMISGEELEKMDDEELAEKLGDVTIFSRILPREKMQIVRALRSRGEVVAMTGDGVNDAPALKYADIGIAMGGRGTEVAREAADMVLLDDDFSTIVSTIRDGRRIYDNIRKAMEYILVIHIPIALSALAAPLLALPVLLAPIHVVLLELIIDPTCSIIFERQPEERDIMERRPRPVGSPIITKGLLGKAVAQGLAIFAAAFGSYYLTLRNGDAEHARTFFLTVLVLANLFLVYVNRSDKDFAFAKGNAAIDKIAWLVNISVLFCLIVMSTLPQAAAATKLQPLSLADFITALLTAAAATFWWEGVKWFRRMEGQRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTF5</accession>
    <name>A0A010YTF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrimidine/purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.1</ecNumber>
            <ecNumber evidence="3">2.4.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Adenosine phosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Cytidine phosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Guanosine phosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Inosine phosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Thymidine phosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Uridine phosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Xanthosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ppnP</name>
        <name evidence="4" type="ORF">Cloev_0581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cytidine + phosphate = alpha-D-ribose 1-phosphate + cytosine</text>
            <dbReference type="Rhea" id="RHEA:52540"/>
            <dbReference type="ChEBI" id="CHEBI:16040"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine</text>
            <dbReference type="Rhea" id="RHEA:13233"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:16750"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine</text>
            <dbReference type="Rhea" id="RHEA:16037"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:17821"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="EC" id="2.4.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + uridine = alpha-D-ribose 1-phosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:24388"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + xanthosine = alpha-D-ribose 1-phosphate + xanthine</text>
            <dbReference type="Rhea" id="RHEA:27638"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:18107"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nucleoside phosphorylase PpnP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="3"/>
    <dbReference type="EC" id="2.4.2.2" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A010YTF5"/>
    <dbReference type="PATRIC" id="fig|866499.3.peg.621"/>
    <dbReference type="HOGENOM" id="CLU_157874_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047975">
        <property type="term" value="F:guanosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009032">
        <property type="term" value="F:thymidine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004850">
        <property type="term" value="F:uridine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01537">
        <property type="entry name" value="Nucleos_phosphorylase_PpnP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009664">
        <property type="entry name" value="Ppnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36540">
        <property type="entry name" value="PTHR36540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06865">
        <property type="entry name" value="Ppnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="106" mass="11706" checksum="831A44BA972CBA00" modified="2014-06-11" version="1">MIEKLENVTAIAKANVYFDGKVVSHTVYLANGDRKTLGLFLPGEYEFGTGDAEIMDLTDGVCQVLLPGSKEWQELKAGESFNIPANSKFGFRCYVPVQYVCSYVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTG2</accession>
    <name>A0A010YTG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441839.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1022802_0_0_0"/>
    <dbReference type="OrthoDB" id="1050422at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="47"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="276" mass="30962" checksum="7649A17C7D767421" modified="2014-06-11" version="1">MNLRTGKLPPLCAKYGRELNGKSGGIEQILEDYTALDRIAVALASEEQNNVALTGPAGCGKTTTVRKLAALIEEGRYARLAGRRVVELNIDLINQDRKKRDLRFKHILDEAEYYNIIIYVDEAHRLSENAGPSNLLNTLKPYITSGGISMLISTTSEEFRQYIARDRAMERRFQSVELREPGRQRLLEIVERVARVRYPQTDITKEAISETTRLAALCAPERSEPARSLELLHYTVSAAQINLPPGEYAKEITADDARGAAALKMDRYLEKDGQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTG8</accession>
    <name>A0A010YTG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase, glyoxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441845.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.636"/>
    <dbReference type="HOGENOM" id="CLU_061385_1_0_0"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07726">
        <property type="entry name" value="ST1585-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037482">
        <property type="entry name" value="ST1585_MBL-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="20"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="308" mass="33912" checksum="72EF7B4D68760F32" modified="2014-06-11" version="1">MYDYGNGIYGVDGHYEIEGMAAVYVLLSEGRAAIIETAHNASLPYLLAALAELGVERETVDYICVTHVHLDHAGGAGSYMREFPRAKLVVHPRGARHMTDPAKLVEGVKAVYGDAETERIYGTIIPVPEDRVIAPEEGRELTFGRMTLVCRDAPGHAKHHMIFFEKSTRSLFAGDAFGISYLWMTGKRGRWAFPTASPVQFDPEAMIATTEMITALAPSRIFITHFGELTNIRETAALLIDGVREYVGITEAAAGDKTKIKAGLAKLYAEAAKENDTKLPAATIEESLPVDLELNAQGLSFWYRQRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTL1</accession>
    <name>A0A010YTL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LUD_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441885.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.685"/>
    <dbReference type="HOGENOM" id="CLU_107893_1_0_0"/>
    <dbReference type="OrthoDB" id="1100576at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="18"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="215" mass="23249" checksum="D0FCFFA35EB14B79" modified="2014-06-11" version="1">MNTSEAKKTSNRKLGESICKALEARGFSAQYAENAEAACERALELIEDGASVGIPGTVTVREIGLPERLEEKGCKIAEHWLPNMTREERKAALIGELEADWFVTSANALAMDGTIVNIDGTGNRVGVMAWAPGKILYIIGVNKIESDVDSALKRARSIASPPNAVRIGMKTPCTAVGRCMDCNSPDRICRVVTMMERAPIGRECHVIIVGEELGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTL6</accession>
    <name>A0A010YTL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3268018_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="41" mass="4808" checksum="43AB3E5B37D6CF32" modified="2014-06-11" version="1">MIRNIINFICDGDKARTNKMCRILRKIVTARALNRLYNLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YTW4</accession>
    <name>A0A010YTW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate dehydrogenase/fumarate reductase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0741</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441989.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.791"/>
    <dbReference type="HOGENOM" id="CLU_014312_8_1_0"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="8"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="4">
        <location>
            <begin position="430"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="555" mass="59929" checksum="C84B2A86CEF7DF80" modified="2014-06-11" version="1">MIKRRTEVLIVGGGGAGLMAAVRARREGRRAALVTKGLLMRSGSTVMAPGAFAAVGPWSQPGDSAARHELDTLIGGAWLNNQRIVRRFTGEMRSLIPELEGFGALFERGSDPSRPALKREGGHSFARAVYMENRIGRELMRALYGEAVRLGVEFYERVFIDRLLLNDSGVCGAAGRRIDAPETMAFESGSVILATGGAAMTYRLNDNSTDSTGDGMALALRAGASLMDMEFVQAFPIGFLAPPCVEGSVAGFLPLARLYNNLGERFMSRYDPRLEQATRDKISRAIATEVRQGRGSPLGGVYCVFEDAEPGYIEENLPDFASTYKMCGIDPLRERIEVCPTCHFFMGGVKVDDDWQSDIPGLYAVGEAAAGAHGANRVGQNALAEMLASASIAAGHASQRNALVSGINCILEDDGGEASGAAMLSVPRLRLELQALMQQNAFVVRSGASLRLALEGIERLRSMAGRAVGKERRHGRADIEALENDNMLLVAQCVVSSALGRTESRGAHFRTDFPEADDANWLKNTVVRRRGENLCLSYEPVEFCYHSPREDGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YU75</accession>
    <name>A0A010YU75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="10" type="ORF">Cloev_0836</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442063.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.889"/>
    <dbReference type="HOGENOM" id="CLU_009583_18_5_0"/>
    <dbReference type="OrthoDB" id="83240at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="10"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="306"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG78708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="493" mass="54557" checksum="3A0A069450218FBC" modified="2014-06-11" version="1">MEKEHEFVLKILHVSPECAPLAKKGGLGDVAGALPKALRKNDIDARVLMPAWPGVLDRARELSALPSRPLGTVSAALNWRSLSAKLWRASIDGLPIYILENDELFANENIYPEEMSAATAEPMIFLSYAAFELSRAARWKPQIIHAHDWPTAIIPSALRWHRHYSSMAGDFDSVYTIHNMAHQGLFQQECLNGWGFLPDSFSALDPASLEFYGLVNLMKGAINTSEAVTTVSPSYSWDIQTHDGGFGLDGVMSTNKSKLRGILNGIDYDVWNPHTDPLLPAHYDVSHRDGKKSCRRALMEGFGWEDDGRPLIIFVGRLTEQKGVDIMLEALERFMPDKIFALIIGSGNEFYNRKLSDFETSHSSSVRTVTAFSEESAHLAYAAGDILLMPSLFEPCGLSQLIAFAYGTIPVARATGGLADTVIDADSSPDGTGFLFTDYSIAELEEALNRALAAKDEPERWSRIVRNAMKEDFSWNSSAKEYAALYRNIISSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUP0</accession>
    <name>A0A010YUP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carA</name>
        <name evidence="4" type="ORF">Cloev_1018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442308.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1087"/>
    <dbReference type="HOGENOM" id="CLU_035901_1_1_0"/>
    <dbReference type="OrthoDB" id="662268at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="3"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="351" mass="38153" checksum="4997FD85D551F59D" modified="2014-06-11" version="1">MKNRVYLTLSDGSVWPGRGHIEAPVEGEVVFTTASCGYPQTLTDPSYNGQIVIFAFPPIGIYGVDKENLEGRRVWVRAALMTGLDETEEGRFESLTSWMAENGRPLISDIDTRQLILKIRECGSMMGRIDLEPHVPGLEELPDTLVSEVSCREMETYGGGELTVALMDYGVKENIIRGMVRRGCRVIRFPHNTRASEVLASGADGILLSNGPGDPSVLDFEAGEIAGMLPCGRPLLGVCLGNQLLARSCGAKTKKLPFGHRGANQPVLECSTGRGILTSQNHQYAVDGDTLAGTDLEVAYSHLGDGTVEGLRHKRFDALSVQFHPEASPGPEDASYIFDNFITRMRAAKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUP7</accession>
    <name>A0A010YUP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_30_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="148" mass="17194" checksum="E5948E60BB9053B3" modified="2014-06-11" version="1">MYGSIPDVELRRFYSLWRDMALVYDEWSKARGISDSAVLVLHSLYYERGGCTQKMICDKWLFPKQTVNSILKDFERRGLIEFSTLESDRRNKLVRLTPAGDDLAGSLIPELSRLERFVMEKMGEEGRRGLIEGMALFVKYFREGSPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YUZ4</accession>
    <name>A0A010YUZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709817.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1211"/>
    <dbReference type="HOGENOM" id="CLU_027562_17_7_0"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038488">
        <property type="entry name" value="Integrase_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025166">
        <property type="entry name" value="Integrase_DNA_bind_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13356">
        <property type="entry name" value="Arm-DNA-bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="203"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="386" mass="43806" checksum="E3860106093635B8" modified="2014-06-11" version="1">MAQLYLTQSVCDKASPRSKRYDLRDTFVRGLFLRVEVSGRKTWYLSYRTPSPEKRLKNKKIISASLVNLATARKIAREYLAKLYLEGVDPAILMNPKRPVYSGVTLRELIDAYEPWVNSHQKSGAVTLRALRLFKEFLDLPVASLSTGCIERWQMDNIGQIKRATINRRIAALQAVTSWGVKHGFLKEVPFKAPKLPQTDSKVVARFLTKEERVSLMAALNDRERQQGKDYLKPAVVLSLNTGIRKGTLLGLKWEDVDFKLRTLSLRAEIMKGGKDAIIPLNKKAYKALADWQKFCGADSGFIFSAPDGSQRNDITRPFMRVVDKAGLKNFTWHCLRHDFASQLAIEGVPLHIIQKLLCHGSIAMTQRYAHLSHNSLEEAVSMLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH14</accession>
    <name>A0A010ZH14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transport protein ChrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0121</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441309.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.133"/>
    <dbReference type="HOGENOM" id="CLU_018106_1_2_0"/>
    <dbReference type="OrthoDB" id="1884249at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="190" mass="19936" checksum="23C69324F103C822" modified="2014-06-11" version="1">MTLLLRLFYEFFKVGLFAVGGGLATLPFLYSLSARSGWFTPTDIADMIAVAESTPGAIGVNMATFAGYMSAGISGAAVATAGLVLPSIIVILLIANLLDNFQERPVVKDAFYGLRPASIALIAASGMNVVAVTLLDLEKFKATGGPADLFAWKAILLGLILFAAQKRLKWSPVVFIAISAAVGVIFNFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH38</accession>
    <name>A0A010ZH38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tautomerase</fullName>
            <ecNumber evidence="3">5.3.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0142</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 4-oxalocrotonate tautomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.-" evidence="3"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709229.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148073_5_1_0"/>
    <dbReference type="OrthoDB" id="2013680at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004370">
        <property type="entry name" value="4-oxalocrotonate_tautomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018191">
        <property type="entry name" value="Tautomerase_Pseudo-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01361">
        <property type="entry name" value="Tautomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00013">
        <property type="entry name" value="taut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; via imino nitrogen" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR618191-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="70" mass="7853" checksum="5B15A7E874E10860" modified="2014-06-11" version="1">MPIVMVNIKEGRTVEQKRAMVTGMTKVLCETMEVPQSSVRIIINEMKNDNFAIAGTLICDDPSKQVKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZH78</accession>
    <name>A0A010ZH78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.196"/>
    <dbReference type="HOGENOM" id="CLU_030756_2_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="250" mass="27471" checksum="248C8EA9F0CD73B4" modified="2014-06-11" version="1">MRPLIGIPTSPFKHSYSEITPVNIDKEEFDYFWLLSVLTEKIVSCVRAAGGVPLLLTATRDAQEIKAAASKLDGFVFAGGSDIAPAFYGEEDRGTISPDLDRDSFELALCREALEKNRPLLGICRGCQLLNVALGGSLIQDLPDVKDDWGLHRRPDIVRGYVHDVKITVPTLFPNNRGETMKVNSMHHQAVGRLAKQAEAAARTEDGIIEAIWAPAYKYAVGVQWHPECLAEDDGVQADIFRAVVAKAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI05</accession>
    <name>A0A010ZI05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441671.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1657778_0_0_0"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="159" mass="17311" checksum="DEE77946692B9B79" modified="2014-06-11" version="1">MGRRIAGSLDDMGRVRRATVELIERVCSGRYKDSSEVAVLPDVLAYYERACGGGGPVPVNVAAGEDAAEVNEFAGLTKEEGGAPTADSFPQTGLVSAAQIAPFLGFTKATHKRPENSVHRLAANGDIPKPVYQGSRMPRWRAEDIREYARTRKYRSEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZI14</accession>
    <name>A0A010ZI14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1003633_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="277" mass="30354" checksum="646586D5ACB90818" modified="2014-06-11" version="1">MSLALGVPECAGYLLDLWLNAAMNRPKGVLYDMDAADIALDAGWDGDVDFFVGALVSCGFLELNEDGVYVLHDWAEHQGYAQFAEERREQARNAANARWAKHRAPAGSAVGMPEQCGEHDSALPADTESNAPSPVPSPSPLPDPKDKDICPSVPAAAKSQRGKADFSPEFEAFYAAYPRRVVKKRAWRNWNVCLKGGASPDELTAAAVAYAERCRRLRTSEEFILHPSTFLGPSEPWRDYVHPPAAREDSGVIGRLSPEEEARQLADIERYLSRGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIG1</accession>
    <name>A0A010ZIG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.670"/>
    <dbReference type="HOGENOM" id="CLU_060196_2_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="1">
        <location>
            <begin position="24"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="263" mass="28129" checksum="8C1479BE9F303634" modified="2014-06-11" version="1">MSVRTAVLIKQVPDSDEIKMDPEKGTMIREGAGNIVNPLDLNALETALSLRGELGGSVTVVSMGPPQADIALRETLALGADKACLLSDRFFAGADSWATSLTLAKALEKLGPFDLIIAGEKATDGETGQVGPEVAAIMDLPCSTYVSSVVCDGKCAVVRRTVEGGIETQRIKLPCLLTVLNDINEPSMPTLRGKKSARRASVDTLNAADLRLSKEEAGLVGSPTRVVKISHPKISRKTEFYSGRELERGFERVLEILRELAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIR9</accession>
    <name>A0A010ZIR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.761"/>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="222" mass="25477" checksum="3CA0BDB1ECABC433" modified="2014-06-11" version="1">MEVASKNEKASWIKVYDWIREGIDSCALKMGEPLPETFLANEIGVSRTPVREALRVLEQDGYIKIVPLKGAFVSEISLEDVREIYDIRKLLEPFAALSAANRIPDGEIKEMSAEWEQLGKRVKNGEHIDFSSVADSDIRLHFTIAKYATNRRIGAILMSYHVQIKRFQRLSAQSLADIQNSINQHIIIIDCLKRRDPKALHNCLYEHVVNSEGYIMKDYFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIV3</accession>
    <name>A0A010ZIV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fumarate reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="6">1.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Cloev_0742</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19522</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a menaquinone + succinate = a menaquinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:27834"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="6">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441991.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_3_3_0"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="187"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG78614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="232" mass="26167" checksum="A6E25FCCD459C86D" modified="2014-06-11" version="1">MMSWVDIRRFDPLDKNACRTQRYQVSLAPGMSVLNLLEQIYSEQDETLAYSRCCRAGVCGLCAVMVNGEPRLACRTAASPEMLLEPLRGFPVRKDLLIDREAYEAHRSRLHLYLERQSCRGARAEALEPVAREDFERFKIPSRCVECYCCVAACPAYKAHPDTFLGPCSLVLLARHSFDPRDTMDRRPLALEAGISRCINCKKCDAVCPMGISPSSVIAALKQQIEEEHHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZIX7</accession>
    <name>A0A010ZIX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442016.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.814"/>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_0"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="11"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="378" mass="40757" checksum="016E0C6E5A1714FD" modified="2014-06-11" version="1">MEKFSSITTIYMGKDALADAVGGARRVFIVSDPFMVSSGKVSYVTDYLQGSGAEYEIFSDVQADPDIETVAAGMARIVEFKPDHVVVLGGGSPIDAAKAIVFFAHRQGAIPPCPFTAIPTTSGTGSEVSSFAVITDHKKNVKYPMVDDSLLPTSAVLNAELVMSVPPKVTADAGLDVLTHAIEAFVSTNRTDFTDAMAEKAIKLIYRYLLTVYREPGDYEARQRVHNASCMAGIAFSNAGLGLNHAMAHTLGAKFHIAHGRANAILLPYVMSFNAGCATQLTDTAKRYAKIAYLCDISTVSVRQSALNVIRTIRSWTRKMDIPPTIREAGVSEADFRGKLPEMVEDALADGCLTTAPRRCTGDDIRQVFENAYNGKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ13</accession>
    <name>A0A010ZJ13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribulose-5-phosphate 4-epimerase-like epimerase or aldolase</fullName>
            <ecNumber evidence="2">4.1.2.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.17" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442032.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.844"/>
    <dbReference type="HOGENOM" id="CLU_006033_3_1_0"/>
    <dbReference type="OrthoDB" id="599627at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008738">
        <property type="term" value="F:L-fuculose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="8"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="213" mass="22605" checksum="012C737FDD794270" modified="2014-06-11" version="1">MTDLEIRKDIIETARRMLEKGLVQGTGGNFSVRCEEGFIITPSGMDYATLTSGDLPKLSPGGAVLEGERRPSIEKELHREVYLARRDVCAVVHTHSVYATAAAAMRLPLPVLTDNQAVLFGGPVPVAEYAPIGTPELARGTARALGDGAGVLMANHGALCVGATLREAAQRCEMLEIFAKIFFLTKSCGGGVCLTAEQAGSEAADLAERYGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJ37</accession>
    <name>A0A010ZJ37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type oligopeptide transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442038.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.864"/>
    <dbReference type="HOGENOM" id="CLU_017028_0_3_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458317" evidence="1">
        <location>
            <begin position="25"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="73"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="560" mass="62688" checksum="897762D9773F4F98" modified="2014-06-11" version="1">MSIKKSVRSIVVIVLAIAALFSQAAGSYAAPKVLVFNHGKEIKAWDPSIDDSGGSFVIGNIFEGLMKDTKDGKLVPGQAEKYTISPDGLTYTFYLKPNITWSDGKPVTAKDFEYAWLRLLDPKAGSEYSYMGTSYIKNAKAFFDGKATADKVGVKALDEKTFQVILESKVPYFLNLTTFFSFMPVRKDIVEKHGDGWEKNPKTCISNGPFVLESYKIGDNLTIAKNPKYYGSKNVKIDKVKMVFVSDQTTALNAFNAGDIHVNPEIPPAEIPRLIAEEPNLVFTPRMQTAYIIFNVDKPPFNDVRVRKAFALALNRKAICESALKGGETPATGVVPPVLSLSTGESFRTLGKNGKPAAEYGIDPNAARVKEAQKLLAEAGYPNGKGFPKVTYTYVTRESLKKMSEAIQEMLKNNLNIKVELDNMEWQVLVDKRKRGDFIISGGNWTGDYADPMTFFDAYAVDSSWNECQWRWKRSKVAPNDTVLNPEHKAFEQEILMAQKTSGKTRDEHLKNAEKILMDAAPVSPLYYGNFCYLVNQDKVRDVWMNKVGEYKFWDAEMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZJX7</accession>
    <name>A0A010ZJX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="5" type="ORF">Cloev_1122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711251.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_1_3_0"/>
    <dbReference type="OrthoDB" id="2092354at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="66" mass="7425" checksum="FB6F75DB8725FEC9" modified="2014-06-11" version="1">MATPKRRVSHARTHNRKAQWLGELEAPSLTACKHCGEMIQTYCACPACGYYKGRQVVKIAEEKTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL44</accession>
    <name>A0A010ZL44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Precorrin-3B C17-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441269.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.100"/>
    <dbReference type="HOGENOM" id="CLU_047948_2_0_0"/>
    <dbReference type="OrthoDB" id="1195697at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11646">
        <property type="entry name" value="Precorrin_3B_C17_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006363">
        <property type="entry name" value="Cbl_synth_CobJ/CibH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01466">
        <property type="entry name" value="cobJ_cbiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG77987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="245" mass="26158" checksum="3F61A52D8DF1A588" modified="2014-06-11" version="1">MIYVVGLGPGGPEQITPRALSALEKCDLIVGYKAYIELVRPLFEGRKELVASPMKKERARCLEALELSLSGRTVGLISSGDPGIYGMAGIMLEVAGDRTEVEIIPGITAAASSASILGAPLMHDFAVISLSDLLTPWELIEKRLRAAAEADFVICVYNPASRGRPGHLARAAEILMQRLPRDRAAGWVRNAGRDGESFGLTTLAGLKEAPIDMFCTVIIGNSATRVIDGRLITPRGYKDPAGGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZL67</accession>
    <name>A0A010ZL67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na+/H+ dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0114</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709190.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.126"/>
    <dbReference type="HOGENOM" id="CLU_019375_7_2_0"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="414" mass="43942" checksum="56CD26319D10CE7E" modified="2014-06-11" version="1">MSESNSVWKAYRFPIILLCAIAVGCVIGAVMGKDALVLKPLGDLFINAMFMVVVPLVFTTICSAVASMSSMERLGKVMRSLVVVFLITGALAAILMLVTVTIFPPAQGANIQMQAAGEIQAFSTPDQIVKAFTTDDFVNLLSRRAMLPLILFTIFFGFCLQSLGERGRSIGRGISVVADAMLQMVKYLMYYAPIGLGAYFATLVGDYGPQLLGAYFRSMVVYHVATFGYFFVAFTIYSWWATDGRGVRVFWSKIIAPALMALGSGSSTATLPINLEAATNMGIPRDISEIVLPIGATAHMEGSCLSGILKISFLFGIFGLPFTGLGTMATAVAVAVLSGVVLSGIPGGGLVGEMLIVSLYGFPPEAFPIIATIGFLVDPAATMVNATGDTCSALIISRLVEGKDWFAKAKVTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLF4</accession>
    <name>A0A010ZLF4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LPG_synthase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709326.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058411_0_0_0"/>
    <dbReference type="OrthoDB" id="1502336at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016732">
        <property type="entry name" value="UCP018688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41373">
        <property type="entry name" value="PTHR41373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018688">
        <property type="entry name" value="UCP018688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="LPG_synthase_C" evidence="7">
        <location>
            <begin position="59"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="301" mass="35102" checksum="C2F82B087CD0DB81" modified="2014-06-11" version="1">MDLNFQEITLEEAPRYIAHWNMCEQRTSDYCFPVIWSLGADFGTKLAYDESTDLYWLHQSKVGLADLAPVGNWRRDDWPRILRERYGDEMEFFLVPEKLAEIWCSELAGKANVEVVDDRGTWEYLYNIRELATLAGNKYMKKRNRVNQFRKNYDYVYEPMTDGLLPEVVDFQYSWCQVNHCGTTAGLMQENHAIQKILQNWNRIPNLCGGVIKIKDQIVAYTIGELAGDMLVVHYEKASLEYGAAYQVINREFLSHIIGLHPELEIVNREEDMNDPGLRAAKMSYMPIGFLKECRVEIKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLQ8</accession>
    <name>A0A010ZLQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484802.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_0_0"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="134" mass="15522" checksum="49CB374872CE5EC1" modified="2014-06-11" version="1">MYTVKQTSEITGISGYTLRFYDKEGLFPHLNRDGQNRRLFSDEDLHNIETIQELREMGFSLAQIRSYLTAEEEGGMKRRRELLAEQMDRIRSELAAITRRMKKLQQAAEYYQVDIKGWVNVMPADGASPVIFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZLT2</accession>
    <name>A0A010ZLT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Fe-S center protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_0310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441487.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.339"/>
    <dbReference type="HOGENOM" id="CLU_046240_0_0_0"/>
    <dbReference type="OrthoDB" id="1000643at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="346" mass="37407" checksum="B1B4FDF0BE523F9E" modified="2014-06-11" version="1">MPSVYFTGSGKLRSEYDASEAAARLMLTVSEREGIPFGRSVPLKVHFGERGNESFIRPALYDGIIDALLARGVASSFMETSVLYAGPRMRRESHMRLAAEHSFTRLPVVIADGEAGESFYEVPIGKKHFKSCKLGAAFRDFSRFVVLSHFKGHRIAGFGGAIKQLSMGFAAKGGKLAMHMGIKPFIFRPLCRRCGLCAANCPVHAIAKDGAYRIDAAKCIGCGACFALCPHKAVSIYTPKSIVHALLRRGDFLERLAEYAYAAALGRRNIYVSYAMNVTANCDCIGKKMSPLIPDVGIFASADPVALDAACLDAAAAAGARFKGRRQLEYAEEIGLGSAKYELISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZM38</accession>
    <name>A0A010ZM38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor SigS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441604.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1642918_0_0_0"/>
    <dbReference type="OrthoDB" id="1922848at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="11"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="5">
        <location>
            <begin position="113"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="163" mass="18394" checksum="815EA035A2A3F14A" modified="2014-06-11" version="1">MNGEAQVREIVDSYTPLVRATARRYEGRGADYEDLVQEGYLALLILIPKCPDMKWLAHFLKNNLPGLVRDAAARMRRGRAQGDEVLLEEIEETVGAEEEGYREAELRAILFRVLTPEELDLTQALLEGFKQREIAENLGVSQQAVAARLRKIKDKLKGIIASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMC4</accession>
    <name>A0A010ZMC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0178 protein Cloev_0516</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0178 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709623.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.553"/>
    <dbReference type="HOGENOM" id="CLU_106619_0_0_0"/>
    <dbReference type="OrthoDB" id="1890924at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00489">
        <property type="entry name" value="UPF0178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003791">
        <property type="entry name" value="UPF0178"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35146">
        <property type="entry name" value="PTHR35146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02639">
        <property type="entry name" value="DUF188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="145" mass="15660" checksum="5656608126946D83" modified="2014-06-11" version="1">MRIIIDADACPRGAFEAAAKTAAAANAELITVANFNHEIASEHHITVGGDPQEADLKIINLARAGDIVITQDIGLAAMALAKGARALGPTGFEYVGKQMEASLEERELKAKYRRAGGRTKGPAKRTKEDDRRFTAKLAEMTRREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZME3</accession>
    <name>A0A010ZME3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative regulatory ligand binding protein, C-terminal domain of K+ channels like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441783.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.575"/>
    <dbReference type="HOGENOM" id="CLU_112362_0_0_0"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="2">
        <location>
            <begin position="124"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="218" mass="24070" checksum="EC88ECF3D7C9A313" modified="2014-06-11" version="1">MTEEDVPVSSPRYRQVAVDIAAKIVNRQYRVGERIYARSLIASTYSVSPETARRAIAVLADLGIVEATKGSGVHIISYDNAMKFLRQSKDYKTLSGYRHSIKKMAEEVFSQCGKLKDEIESLVSHAEQFRSSNPFTPYEATVQEGAPCTGRSLSDLKFWQNTGATIVAIGRGGACMLSPGPHMSLREGDVLYYVGDERCIDRVLHLTKGELSLSNANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMH9</accession>
    <name>A0A010ZMH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Cloev_0580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484844.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.620"/>
    <dbReference type="HOGENOM" id="CLU_896310_0_0_0"/>
    <dbReference type="OrthoDB" id="1435118at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000210">
        <property type="term" value="F:NAD+ diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015376">
        <property type="entry name" value="Znr_NADH_PPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09297">
        <property type="entry name" value="zf-NADH-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="179"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="310" mass="34211" checksum="7C69C10754457DAE" modified="2014-06-11" version="1">MSFYYIFQNGKIILKENGAIPEATDAGKFRKNFLNSGCVDKEDNAACAADASAGLPPEEIYDVRAGRGQGAACAADASAGLPPEEIYDVRAGRGQGAARVGDRWAELDTEAALPEGFAACERRGCWTAVGEEQFFRIGKAFHIMDWQRLHKHCGRCGAANLFDPAEGAMRCPSCGELFYPVISPAIIVCVEKEGKILLGHGVNFPAGRYSVLAGFVEPGESLEECVAREVYEESRIRVKNIRYFNSQPWPFPRSLMLGFVAEWESGDICPDTTEVTDVRWFAPGEIPEYYRGISISAKLIEDFIKRHTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMI8</accession>
    <name>A0A010ZMI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_0590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441837.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1460607_0_0_0"/>
    <dbReference type="OrthoDB" id="1596830at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="188" mass="21654" checksum="A2EB88D24FDFDA4A" modified="2014-06-11" version="1">MLKSTLEIYGKYDQESKRHCAELAKKTLEQIHREYLEAVFTAAVRRRLDIWDFAQKFMELDFSLSLDRPETLLSLKMDEVFRDFMVRCAQQGVEIETVPHEKAGMAAFRDISPEAEWLVGLYSKWHARTGEAGCEIAERAPAALLKKIHKKAMTRRLDEVISLLIENSAEAALISSKDYEMLEEISRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZMJ2</accession>
    <name>A0A010ZMJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATPase (AAA+ superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441844.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.635"/>
    <dbReference type="HOGENOM" id="CLU_047370_0_0_0"/>
    <dbReference type="OrthoDB" id="801313at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041682">
        <property type="entry name" value="AAA_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025420">
        <property type="entry name" value="DUF4143"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13173">
        <property type="entry name" value="AAA_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13635">
        <property type="entry name" value="DUF4143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_14" evidence="1">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4143" evidence="2">
        <location>
            <begin position="226"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="454" mass="52080" checksum="171EDADE1DCAFB39" modified="2014-06-11" version="1">MLRRKAYDKLMEWKGTKKKKALCIIGARQIGKTTLIREFGRQNYENFVEINFVTDDGACEIFAGSLDADTIITNLTAYVRRSMEPGKTLVLFDEVQKCPDVRTAIKFLVEDGRFDYIESGSMLGVKHKEVKSYPVGFEEIYRMYPMDFEEYLWANGVQVSTIAYLKKCFDDKTPVSQSVHNTMKKLFYSYVVVGGMPEVVQTYVDTHDIGRVITNQRDILEQYRLDIAQYAEGNDKIKIRAIFDSIPTQLNEKNRRFYVNYLDKNARLTRYDNSFKWLDDAGVALPCYNVKEPKPPLALNEKHSLFKLFMNDTGLLCAACMDNIQFEILNGRLEINMGSILEDAIALQLKANGFILRYYDSKRHGEVDFVIQNGMRIDLAEVKSGGDYKKHKALDNVLGVEGWSFGGVYVLCADNIETENGITYLPWYLVMFLRPAQVPKGLTYEVDISDLRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZN68</accession>
    <name>A0A010ZN68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484873.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_19_8_0"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="179" mass="20034" checksum="0CDDBA3B3931514A" modified="2014-06-11" version="1">MEFRIRPFRDSDIADINEIRSMRGVMETIPTLFSESVAFTEKVMKSVGPNDPALSAVIDTPEGEKVIGNGVLRLTEKARLRHTASVALIVHAGYHNMGVGRAILSQLLEIADKWLMLVRVELEVAACNEGAIHLYESLGFQHEGRLKYAFMKDGKYEDLLVMGRYNLPVNRRLYAPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNA7</accession>
    <name>A0A010ZNA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose pyrophosphorylase</fullName>
            <shortName evidence="9">ADPGlc PPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgC</name>
        <name evidence="11" type="ORF">Cloev_0835</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="9"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442060.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.888"/>
    <dbReference type="HOGENOM" id="CLU_029499_14_1_0"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00624">
        <property type="entry name" value="GlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023049">
        <property type="entry name" value="GlgC_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha-D-glucose 1-phosphate binding" evidence="9">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="433" mass="48450" checksum="22014D029EE54FBD" modified="2014-06-11" version="1">MIHGKYGRVLGMVLAGGKGERLMPLTRYRAKPAVPFAAKYRIIDFALSNMVNSGLFSIYCLIQFKSQSLHEHIGKGWQFGSALRGRDFFVNVVPAQMWDGERWYEGTADAIFQNMHLVTLFDADRVCIFAADHVYKMDVEQMLAYHMDNNADITVAAYVVPSSEASQFGCIATDAEGRIIDFVEKPAVPPEIPGRPGYSFVSMGNYIFEREILEESVLSDNERKDSSHDFGRDILPMLFKGYKLMAYDFSTNKLPGDDRPYWKDVGSIKAYWEAHMDLLRHPSALSLYNQQWPIRTVSYSDPPGFTYPANDHSCSVDGCLRAEASRVLGAYVRKSVLSRNCVINSGSVIEETIIGQNVHIGENCRLRRVIVDAHNVIPNGTSIGFDPVADTERYHVDPSSGLVVVGMPKIQLRKKLQIPGAYENMFTADGAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNS2</accession>
    <name>A0A010ZNS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G:T/U mismatch-specific DNA glycosylase</fullName>
            <ecNumber evidence="2">3.2.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_1017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1086"/>
    <dbReference type="HOGENOM" id="CLU_094865_1_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026353">
        <property type="entry name" value="Hypoxan-DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04274">
        <property type="entry name" value="hypoxanDNAglyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="161" mass="18645" checksum="0E5BDC9C1249F373" modified="2014-06-11" version="1">MKYSFGPVINDSSRTLILGSLPGEKSLAMSSYYAHPQNHFWKILYRVFGETMPDSFQERYDFILRRRLALWDTIKCARRAGSLDGKIRDEEPNDVPSLLALHPNISLILFNGACAFAKYKKYFGEPARHYRRMLSTSPACAGRNDERYRMWEEALRQGTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNW6</accession>
    <name>A0A010ZNW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rex</name>
        <name evidence="8" type="ORF">Cloev_1077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442368.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1146"/>
    <dbReference type="HOGENOM" id="CLU_061534_1_0_0"/>
    <dbReference type="OrthoDB" id="1872374at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="84"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="19"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="94"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="218" mass="23413" checksum="90F793DB013DED3F" modified="2014-06-11" version="1">MPNTKPLSISRQSLQRMPLYLEHLKKLRADGSSHVSAAFLAAELGLHPVQVRKDLAAVSKVDGNPRVGFALEGLIEDMAEFLGCKNAHEAVVAGVGNLGRALLSYKNFDRYGLSIIAGFDSDPAIIGTTVHDKEIFNVSRLSELCGRFAVHIGIITAPAQFAQDICDAMVLGGIKAIWNFAPVHLNIPDDVIITNENLAASFAALSSRLRQRGEGLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZNX0</accession>
    <name>A0A010ZNX0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="2">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Cloev_1082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="2"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442385.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1151"/>
    <dbReference type="HOGENOM" id="CLU_004620_5_0_0"/>
    <dbReference type="OrthoDB" id="70707at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG78927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="477" mass="50847" checksum="0EBF49E45810B645" modified="2014-06-11" version="1">MKLIYERSVPGRESAILPASALPFGGISAGMKREKPLRLPELSEVDVCRHYTALNKQVYGVNCGFYPLGSCTMKYNPAVNEEVAALPGFQNIHPLQPEETVQGCLEVLEALGSRLCELVGMDAMTFQPAAGAHGEFTGLLLIKAYLRDNGGAARNKIIVPDSAHGTNPASTSMTGFQIVNIPSAQDGSVDLDALRAAVGPDTAGLMLTNPNTLGMFDKNILEITRIVHEAGGLCYYDGANMNAIMGTARPGDMGFDVIHLNLHKTFSTPHGGGGPGAAAVGAKEILAKYLPGRSAVKTETGYAFKDDPASIGAVRSFYGNFLVCVRALCYVLSLGGKGLHEASQNAVLNANYLRVLLKKHCPTSNEGLCMHEFVLTLEELHKETGVSASDLAKGMLDCGMHPPTMYFPLIVHEALMFEPTETETKDTLDEAAEAVISLLKEARSNPEALHSAPVTTPIGRPDEVAAARTPIIRCALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZP19</accession>
    <name>A0A010ZP19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Cloev_1137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709819.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041895_0_0_0"/>
    <dbReference type="OrthoDB" id="1383921at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG78977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="454" mass="50949" checksum="9BB4A6377AA3AF67" modified="2014-06-11" version="1">MASVVARALVAIDADKASKQDLELLKKLVMEFKDELDALGVKVDKIDKRVAVLEDRLGGWKLSGQFWFDANFAGGDQAGSAYTSNGLDTDFEKDRFRLTLTKQISDTTSFYAQFRAGSEGSGGKSGYGDVDGFNIRQVYVDTVLPYGVGYRVGRFFLDFEGDHDLYIDNDAIYGDYRVDGFQFTKTWNTFSAKAVIGRNTFSGAYKSPAYRINGAGDVVMNSGNLYDTAQMHYALDLTWQPNEKFFIGANGVWVKDDSDLAAMEDMDYNTYSVYASYNFTPAVALQGTYYWQDLDEGIAGGFEDSPKAWRATLAVKQDLLKFTGLRFEYQQQDNTFNGVRDPYSFGVNSANAASISDNMPWNDGTTKLFFIYADQKWNDKWSSYLRYQQADFDTTGLDDAKGYGAGVTYQYTPAIAFRLAYDCVDYGDGNIFNHGDDFKDGKDHVFQFRTAINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A787</accession>
    <name>A0A011A787_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484731.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041771_1_0_0"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG77916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="369" mass="40821" checksum="3F91044CE4FF1CFF" modified="2014-06-11" version="1">MRPHEESVNFFGGDNMPFIIFFVLFAFLAWDITAPISTPILWAAVLSFISMPIYRLISRRLMRNRFPSVASGVTLALLLLICIVPVLYALSTLGSEAAGMGAKFSQLLAKIQHQAYSGRDFDFPAWLPLWAADYLTSFLENSDAVKTALQFFAQWSAKFLSSLSAHIIEQGSSFILNAMIATMISFFFIRDGEKIVNYVKSVVPLSPEENEAFFFRTGSILNSIVYGIILTVALQALVGGVGWWFVGLGSPALFGMLMFFFGMFPAGTAVVWVPGSIYLALTGDIKNAAILFVWGLLVVGTIDNLLRPFLISGGRSGRGEIPTLLIIMGLFGGVMVWGFLGIFVGPLILVLFVSVCDLYRKRWLRRQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7C6</accession>
    <name>A0A011A7C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate-binding protein similar to pyruvate phosphate dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG77956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484748.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015408_0_0_0"/>
    <dbReference type="OrthoDB" id="218209at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="1">
        <location>
            <begin position="31"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG77956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="584" mass="66582" checksum="1680D45598DAFFB1" modified="2014-06-11" version="1">MTSADRARELYFEWQPHDDPEFAPLICGRGTIGGKGRSLLFALRQLRDSGDEQMSRTKVPRSIYLSIEIFHQFLEKVPRLGTLLANNDPQEIERVFLETPLPETAGMYIRTFLADMHDPVVIRSSSRLEDDVKHSFAGKYLTNFLGNNCGNLEARAAAVENEVRRIYSRTFFPAAADYRARHDLGDDDMGIIIIRMAGRWRGRYYYPTMAGVGYSQNFRRWTTRVKQDDGLVRMVFGMGTMSTKRGYARTVSLTNPILRPEGFAPERISAIAQESFHVIDEERPNQITTLDIKKEWKQLLTYHPDFAAYAQIYRCDEGEGCFFQIMKNMASLSPGTKVCFTFDSFPRMYPDFYKRIKKTLKLLEGKMGVPVDMEFAFEPTEDSFCLIQARPFWSNNHLEGGIPALSPKQILLQADRMVTHGAIPQITKIVYVDFNLYYAQRDFYGTARLLGELNRASDGEPYLLVAPGRIGSSNPELGVPVQYSELTNCRGMVELGIPRLGFMPELSYGTHFFSDLEVDGVLYMPVFAGEDRNIFNTDWFESKSWEPWCSPAIRVYRGNFAAYMDGETNRGVIVDKDMGEENGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7H2</accession>
    <name>A0A011A7H2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441294.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_2_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="62"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="336" mass="37841" checksum="FA8F5BE6C92F678F" modified="2014-06-11" version="1">MEFRPHGANPEKLYQQFGIPMPERVFDFSTNTNAVAQRGGFSPDLRAALEDYPDDDCAALRAFLSKTTGAAPEDILVTSGSNESIYLIASYEKDRKNLILQPTYGEYLRALENFGAAPCNIFDLRAAKLPQGGSVWLCNPCNPTGSFIPDAELDEIAASHPRTLFIVDEAYRDFIWTEEEPLPYRPHPNVIRLRSLTKTYNLCGARIGYILADASVTERLKKRQPSWSVSGLAQQAALFFLADDALLRRTRDYYAAEMPRLISAVNGAGFATLPTCVNYFLARTDNDEKLIRFLLERALVVRHTRNFPGLEGKFVRIAARTREEDDLLTDALRDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7P4</accession>
    <name>A0A011A7P4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PLP-dependent enzyme possibly involved in cell wall biogenesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Cloev_0186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19522</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008709293.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.203"/>
    <dbReference type="HOGENOM" id="CLU_033332_7_2_0"/>
    <dbReference type="OrthoDB" id="1722208at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG78081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="387" mass="42492" checksum="6B00159E5D4F9069" modified="2014-06-11" version="1">MRKEFLPFAKPSVSEEAISDVADSIRSGWLAMGPKTIRFEETFAKYTGASYALSVNSATAGLHCALMALGLGPGDEVITTPMTFAATVNAILFTGAKPVFADIDRETLDIVPENIERAVTKATKAVIPVHFAGMPCDMDKIEAIAGAHGLAIVEDAAHALGASYKGRRIGADRGARRLSVFSFHPTKNITTGEGGMICTGDEELAEKIMVLRQNGMSKGAWNRYAAKGSANYDIFFPGLKYTMMDIQAAIGNSQMRELPEFNRRRAELAAFYLRELAGVKGLILPRRAPWEYEHSWHIFTPFVDIDRLGFSRDEFMARMKERNIGTALHYQALHLFTCYREVTGMDRGDLPEAEYVSDRIVSLPLFPAMTDGDARDAAAAIREVCGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A7R5</accession>
    <name>A0A011A7R5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441382.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053146_2_2_0"/>
    <dbReference type="OrthoDB" id="1906220at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="319" mass="35932" checksum="0D93002772A86C13" modified="2014-06-11" version="1">MTASFEREEKFFKYKKPRETKCGIKSRTARGHAYGSNWWSRRWVEIMEQCIDSGRLARGKSYARKGQVVNIHIEPGLVTAFVQGSRKTPYQIRFGFETLSQEARELILFRFGESAALAAKLLAGEMPEEIEAIFKEAGTPLFPARETLRRFKCTCPDDATPCKHIIAVLLILGEELEDDPFLLLKLRGLDKESLISLLTLENAPDDEIAEAGAEYEWESAGELSGGAEAEAETGAPVREEVPPADENWYGGGEFSFERAEPDVQRRAAALDVMNDFPFWRGEHPFRQTLAPFYEHAAIYAGEILTGEKKKPVGRPRKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8D9</accession>
    <name>A0A011A8D9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="1">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Cloev_0367</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="1"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051484817.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.402"/>
    <dbReference type="HOGENOM" id="CLU_002360_3_3_0"/>
    <dbReference type="OrthoDB" id="178322at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="696"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="722"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="764"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="795"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="832"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="862"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="11">
        <location>
            <begin position="12"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG78256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="891" mass="95404" checksum="7656151B7CB1FFA5" modified="2014-06-11" version="1">MQLNEKYPARREAFRESAAETLKRLGVDPRRGLSTEEAAQNRRRYGENSFTKKKPVSMLRRIAEAAREPMIIMLIAAALITLGVNIARGLSGGEADLIECAGIFAAISLSIAITVAMEGRSARAFEALNRITDDAKVRVIRDGEAELIPQREVVVGDIISVETGNKFPADARLIESSSLTADESALTGESMPAGKEAEAVFADPETPLAERANMLYSGCFATGGGGLAVVTAVGDATEFGKIAGELSAAESSATPLQEKLAKMGKRIALLATGTAAAVFLIQLASFIAKGAASLETVSEAFITSIVLIVAAVPEGLPTIVAVSLAINIIKMSKHNALVKKMAACETIGGINVICSDKTGTLTENRMTVTDVCGGGEPRGPRELGAGALIDNFCLNGTAEVRFEEGKAAFIGNPTECALLVAAHDAGFDYRALRRERNVLHTFPFSSETKNMTSVVTNGTSITAYTKGSPEKILSMCSMTDGERREAAARITEFQERARRVIAFAHRELSPGEDYGSSREAIESGMAFDGFAAIADPLRADVFEAVERCRGAGIDVKILTGDNLTTAAAIAGELGLLDEGHCAAEARELEKLSDAELAERLPAIRVIARSTPSIKTRVVRILKTLGNVVAVTGDGINDAPAIKNADVGIAMGISGTEVSKEASDIVLLDDSFATIVRAVQWGRGIYRNFQRFIQFQLTVNLSSVLVILLSVVAGFQAPFTAIQILWINMIMDGPPALTLGLEPVRGDLMDQPPIRRDANIVSRGMLWSITINGLYITAVFMAQHWTNFLGGTEAELSSILFTLFVVFQLFNAFNSRALGDVSILRSFGSNRLMLGVFALTFALQVLITQYADGLFRTVPLPLAMWLKIIALGFSVILLSELVKLARRRFRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8K1</accession>
    <name>A0A011A8K1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3042017_0_0_0"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="54" mass="6141" checksum="E6CA6A2F9A5201A3" modified="2014-06-11" version="1">MEQIAQSEFFYHHIAPNLMLVKAVFFFGIFGLIGVVAQSVRIGQEKEELEEKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A8V2</accession>
    <name>A0A011A8V2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DMT(Drug/metabolite transporter) superfamily permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_0566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_1_0"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="14"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="160"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="303" mass="33460" checksum="106EE27EF12C1171" modified="2014-06-11" version="1">MFSDMKKESFLQVYILATLTVVFWGASFAGAKVALEQADPLLVMFLRFVLSLAMLLPTAWYCGELALPTPRQALVLAFMGFMGFFFHIGIQTVAMRSSGSATANWQMAAAPAMTALLASFFLKERLPRVGILGIILAFLGVTVVLGLGTKGARGASSYNFGDFLISLSVINWAAFMVLTRWLFKENRYPPVFTIFWEIFFAVLMCLPALALTGTDISVSAGFSRRTWEALAFLGFLCSGLAYVFWYYAAANIPVAKLMVFQFLQPLVGVVVAYFVIGERFTPWLFLGGAMIVSGVWTVNRRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9A8</accession>
    <name>A0A011A9A8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Cloev_0739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034441985.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_0"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG78611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="334" mass="36777" checksum="76840CF037537C13" modified="2014-06-11" version="1">MKVLVTGSGGFIGYNMCLDLLRRGHSVVAAYRSSMPDDLARAAREYGGRLEPVKGDLLDPATYERLAPLGIEGVVHSAVITCPNISERDAYVYMVRNNIDSTVNLVEFCMKHEIMNFVYVSSSGVYGSLYGAGATVSEEAPLDLYSTYTVTKRSCELIVARFGAITGARAVSARISSPYGDFERVTNSRANMSPPYMMVHAALDKRRLVIHGPDLGRDWTYVDDIINGIYLLLTVPREQLRHTEYNVSCGEPGTNRDIAQAVLAAEPDFSYIFCKDTEEADMVLFPPITRGAMDIGRLKADTGFQPRFSLKEGIAKYCAHQKRQNERAGDGANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9N5</accession>
    <name>A0A011A9N5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diguanylate cyclase (GGDEF) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Cloev_0860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442086.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.918"/>
    <dbReference type="HOGENOM" id="CLU_021245_2_0_0"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="5">
        <location>
            <begin position="106"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="322"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG78731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="448" mass="49529" checksum="2001EC0404C0160A" modified="2014-06-11" version="1">MCINKETVAKKGAFAAVFLGTLMIVLAIGAAYVNNKFKMECAQMEQLVVIKSNKVNDVLCKLLYKTQVLSALVIQNNGGIRDFEKVAATIVDDPAIRNVILAPGGVVKKVYPLKGNEGVIGLDYFSAGKGNIEALQAKNGKRLVLGGPFDLVQGGQALVGRLPVYTGRDSVEEKFWGLVSVTLNYPEALNGAELDQLKAQGFAFEIWRINPDDGKRQVIAHSSYLYDKGANYVEKPLTILNAEWYFRLSPIRRFYQYPETWMFFFAGLLVSWLIASLVGHNHDLKKIKVELEELTGMDLLTGTLNRRGLFKELGALMGVPGTEFILCYIDLDKFKEVNDSYGHMVGDRVLKHVAAVIGRRIDAGSIFARIGGDEFVLIFKDTDDREMVKAFFDKIAGELLDSLNIAPNGDRLDITFSMGMAAYPSQAKDIDGLIGVADRAMYKDKKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9N9</accession>
    <name>A0A011A9N9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type spermidine/putrescine transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Cloev_0866</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442094.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.929"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG78736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="364" mass="39759" checksum="B23871FEA348CDB2" modified="2014-06-11" version="1">MAVDLHLKNITKTFIKDGVKFDAVERVDLEVAGGELVTFLGPSGCGKTTTLRMVAGFEAPTSGRILIDGADVTEVMVNKREIGFVFQNYALFPHMTIGDNVGYGLKMRSESSADIAGKVGEALEMVGLKGTERRYPNQLSGGEQQRVALARVLVMRPKVLLMDEPLSNLDAKLRLHMRTEIRSIQKQLDITCLYVTHDQKEALTMADRIMVMNRGKVEQIGSPFDIYTHPRTLFVADFIGQANAISGTLDAREGAERGTMRIGERRLPVKLISDAAYSAGDGISLILRPEAVTLRAGGEGLLSGKVTSAVFSGDRMEYVVELENGAPVSVMENYFPGAARYERGEEVALCFNSELTVALPLPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A9R7</accession>
    <name>A0A011A9R7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recA</name>
        <name evidence="11" type="ORF">Cloev_0877</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008710861.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.941"/>
    <dbReference type="HOGENOM" id="CLU_040469_3_2_0"/>
    <dbReference type="OrthoDB" id="1080436at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="9">
        <location>
            <begin position="38"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="10">
        <location>
            <begin position="206"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG78746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="378" mass="40471" checksum="3FF02837751E7B29" modified="2014-06-11" version="1">MAKKAVTKEDILAQALGEIRGKFGDGSIMRLGDEVQHAVEVIPSGILPLDVALGIGGVPRGRVVEIFGPEGGGKTTIALHILAEAQKAGGIAAFIDAEHALDPRLAAALGVDTANLYLSQPDSGEQAFYILDTLVRSGALDLVVVDSVAALTPQAEIDGKMGEGSNQVGLHARLMSYALRRLTSAIAKSKTTVIFINQLRAQISSGYSQGPTETTTGGRALKFYSSVRIEVRRGKQVSQGDVAIGHELYIKVVKNKQAPPFRTAHTTLIYGKGVPKGMAVLDMALDREVMKRKGSWIAYKGESIGQGKDTVASYIEEHPELMDEITKEVLRKVAEGLGLIDEPEHEEPEDSALDDNVEALLEEGVLKLDITEEPEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA70</accession>
    <name>A0A011AA70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Organic solvent tolerance protein OstA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Cloev_1070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19522</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008711170.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789177_0_0_0"/>
    <dbReference type="OrthoDB" id="1911918at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458465" evidence="2">
        <location>
            <begin position="28"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG78916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="351" mass="38199" checksum="EE6ED8C022EB8A37" modified="2014-06-11" version="1">MIIEKRLRRFCAVTAFCLICAALPAAAAPAETVKRQNTLSADDIQYNVNTGDARAKGRVVITRDGSVLKGDEAEGNTEKEVMTIRGNVDGSFPGQQATLKSESATWTGDKTKKTDGVVEAFGKVLLTRAPKDRLNADYVLWEIGTENYKARGNVDGILDNRILKAAEATRTGDKFWARDVRRYEDLVQKFVLSSKTMEGRLAKDAKSGQDTLQEMVADQNVVFDYVDKDGLKTRVTGDKAVYSKARGTIVVSGNTKAVRSDGKTVTADTMVVHEDTRNIEAKGNSKIVFVVEEKAKKEEDAKNTGTAKAGAPAKKGSPSAAETKPASEDKKPAAETKNSQLTDEEKNWVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AA75</accession>
    <name>A0A011AA75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">Cloev_1075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Cloacibacillus evryensis DSM 19522</name>
        <dbReference type="NCBI Taxonomy" id="866499"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Synergistetes</taxon>
            <taxon>Synergistia</taxon>
            <taxon>Synergistales</taxon>
            <taxon>Synergistaceae</taxon>
            <taxon>Cloacibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19522</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="JFBR01000001">
        <property type="protein sequence ID" value="EXG78921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034442365.1">
        <property type="nucleotide sequence ID" value="NZ_KK073872.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|866499.3.peg.1143"/>
    <dbReference type="HOGENOM" id="CLU_023208_0_2_0"/>
    <dbReference type="OrthoDB" id="1257362at2"/>
    <dbReference type="Proteomes" id="UP000023044">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="30"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="143"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG78921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000023044"/>
        </source>
    </evidence>
    <sequence length="343" mass="35793" checksum="85FE7FBDCA971824" modified="2014-06-11" version="1">MAEERDRFLTLGIETSCDDTALAVLEGGHNVLAEAISSQIDSHSAYGGVVPELASRMHQEAILPLLERVLAGAGIAEPARELDLIAVTSGPGLMGSLLVGVMTAKALSQGWGVPLIGVNHLEGHIFANAAVSEALKPPFISLIVSGGHTEVVLVRAFGDYELLGSTRDDAAGEAYDKVSKVLGLGYPGGPVIDRLAAGGDPRAFALPLPLASTKEIEFSFSGLKTAAMTLIGDKTALGEEFPLADICASFQKAVVDSLLVKIKLAVNRTGVKRLTVSGGVAANSGLRAALAEYSRAKGVELFLPPRGMCTDNAVMIAAAGYNSYMRGNRSGLRLSPNPSWSIW</sequence>
</entry>
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Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>